JOSHUA SHULMAN to Drosophila
This is a "connection" page, showing publications JOSHUA SHULMAN has written about Drosophila.
Connection Strength
2.219
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Tau-Mediated Disruption of the Spliceosome Triggers Cryptic RNA Splicing and Neurodegeneration in Alzheimer's Disease. Cell Rep. 2019 10 08; 29(2):301-316.e10.
Score: 0.469
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Functional screening of Alzheimer pathology genome-wide association signals in Drosophila. Am J Hum Genet. 2011 Feb 11; 88(2):232-8.
Score: 0.257
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Genetic modifiers of tauopathy in Drosophila. Genetics. 2003 Nov; 165(3):1233-42.
Score: 0.155
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From fruit fly to bedside: translating lessons from Drosophila models of neurodegenerative disease. Curr Opin Neurol. 2003 Aug; 16(4):443-9.
Score: 0.153
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Tau polarizes an aging transcriptional signature to excitatory neurons and glia. Elife. 2023 May 23; 12.
Score: 0.151
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Functional screening of lysosomal storage disorder genes identifies modifiers of alpha-synuclein neurotoxicity. PLoS Genet. 2023 05; 19(5):e1010760.
Score: 0.151
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Integrated analysis of the aging brain transcriptome and proteome in tauopathy. Mol Neurodegener. 2020 09 29; 15(1):56.
Score: 0.125
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The Drosophila homolog of C. elegans PAR-1 organizes the oocyte cytoskeleton and directs oskar mRNA localization to the posterior pole. Cell. 2000 May 12; 101(4):377-88.
Score: 0.122
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Retromer subunit, VPS29, regulates synaptic transmission and is required for endolysosomal function in the aging brain. Elife. 2020 04 14; 9.
Score: 0.122
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Uncoupling neuronal death and dysfunction in Drosophila models of neurodegenerative disease. Acta Neuropathol Commun. 2016 06 23; 4(1):62.
Score: 0.093
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Drosophila and experimental neurology in the post-genomic era. Exp Neurol. 2015 Dec; 274(Pt A):4-13.
Score: 0.086
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Computational and functional prioritization identifies genes that rescue behavior and reduce tau protein in fly and human cell models of Alzheimer disease. Am J Hum Genet. 2025 May 01; 112(5):1081-1096.
Score: 0.043
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Haploinsufficiency of ITSN1 is associated with a substantial increased risk of Parkinson's disease. Cell Rep. 2025 Mar 25; 44(3):115355.
Score: 0.043
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Tau is required for glial lipid droplet formation and resistance to neuronal oxidative stress. Nat Neurosci. 2024 Oct; 27(10):1918-1933.
Score: 0.041
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The role of PAR-1 in regulating the polarised microtubule cytoskeleton in the Drosophila follicular epithelium. Development. 2003 Sep; 130(17):3965-75.
Score: 0.038
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Integration of transcriptome-wide association study with neuronal dysfunction assays provides functional genomics evidence for Parkinson's disease genes. Hum Mol Genet. 2023 01 27; 32(4):685-695.
Score: 0.037
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Prickle mediates feedback amplification to generate asymmetric planar cell polarity signaling. Cell. 2002 May 03; 109(3):371-81.
Score: 0.035
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TBK1 interacts with tau and enhances neurodegeneration in tauopathy. J Biol Chem. 2021 Jan-Jun; 296:100760.
Score: 0.033
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A Druggable Genome Screen Identifies Modifiers of a-Synuclein Levels via a Tiered Cross-Species Validation Approach. J Neurosci. 2018 10 24; 38(43):9286-9301.
Score: 0.027
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S/P and T/P phosphorylation is critical for tau neurotoxicity in Drosophila. J Neurosci Res. 2007 May 01; 85(6):1271-8.
Score: 0.012
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TOR-mediated cell-cycle activation causes neurodegeneration in a Drosophila tauopathy model. Curr Biol. 2006 Feb 07; 16(3):230-41.
Score: 0.011
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PAR-1 is required for the maintenance of oocyte fate in Drosophila. Development. 2001 Apr; 128(7):1201-9.
Score: 0.008
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Differential recruitment of Dishevelled provides signaling specificity in the planar cell polarity and Wingless signaling pathways. Genes Dev. 1998 Aug 15; 12(16):2610-22.
Score: 0.007