Connection

JOSHUA SHULMAN to Alzheimer Disease

This is a "connection" page, showing publications JOSHUA SHULMAN has written about Alzheimer Disease.
Connection Strength

4.707
  1. Alzheimer's disease risk gene CD2AP is a dose-sensitive determinant of synaptic structure and plasticity. Hum Mol Genet. 2024 10 07; 33(20):1815-1832.
    View in: PubMed
    Score: 0.518
  2. Tau polarizes an aging transcriptional signature to excitatory neurons and glia. Elife. 2023 05 23; 12.
    View in: PubMed
    Score: 0.471
  3. Tau-Mediated Disruption of the Spliceosome Triggers Cryptic RNA Splicing and Neurodegeneration in Alzheimer's Disease. Cell Rep. 2019 10 08; 29(2):301-316.e10.
    View in: PubMed
    Score: 0.366
  4. cindr, the Drosophila Homolog of the CD2AP Alzheimer's Disease Risk Gene, Is Required for Synaptic Transmission and Proteostasis. Cell Rep. 2019 08 13; 28(7):1799-1813.e5.
    View in: PubMed
    Score: 0.362
  5. Tau Activates Transposable Elements in Alzheimer's Disease. Cell Rep. 2018 06 05; 23(10):2874-2880.
    View in: PubMed
    Score: 0.334
  6. Functional screening in Drosophila identifies Alzheimer's disease susceptibility genes and implicates Tau-mediated mechanisms. Hum Mol Genet. 2014 Feb 15; 23(4):870-7.
    View in: PubMed
    Score: 0.241
  7. Genetic susceptibility for Alzheimer disease neuritic plaque pathology. JAMA Neurol. 2013 Sep 01; 70(9):1150-7.
    View in: PubMed
    Score: 0.240
  8. Functional screening of Alzheimer pathology genome-wide association signals in Drosophila. Am J Hum Genet. 2011 Feb 11; 88(2):232-8.
    View in: PubMed
    Score: 0.201
  9. Intermediate phenotypes identify divergent pathways to Alzheimer's disease. PLoS One. 2010 Jun 21; 5(6):e11244.
    View in: PubMed
    Score: 0.192
  10. Dilemmas in diagnosing Alzheimer's disease: The peril and promise of self-fulfilling prophecies. J Alzheimers Dis. 2025 Jun; 105(3):736-739.
    View in: PubMed
    Score: 0.134
  11. Computational and functional prioritization identifies genes that rescue behavior and reduce tau protein in fly and human cell models of Alzheimer disease. Am J Hum Genet. 2025 May 01; 112(5):1081-1096.
    View in: PubMed
    Score: 0.134
  12. Research Participants' Perspectives on Precision Diagnostics for Alzheimer's Disease. J Alzheimers Dis. 2024; 97(3):1261-1274.
    View in: PubMed
    Score: 0.123
  13. Parkinson's Disease and Other Alzheimer's Disease and Related Dementia Pathologies and the Progression of Parkinsonism in Older Adults. J Alzheimers Dis. 2024; 100(s1):S197-S209.
    View in: PubMed
    Score: 0.123
  14. TBK1 interacts with tau and enhances neurodegeneration in tauopathy. J Biol Chem. 2021 Jan-Jun; 296:100760.
    View in: PubMed
    Score: 0.102
  15. Quantifying cognitive resilience in Alzheimer's Disease: The Alzheimer's Disease Cognitive Resilience Score. PLoS One. 2020; 15(11):e0241707.
    View in: PubMed
    Score: 0.099
  16. Meta-Analysis of the Alzheimer's Disease Human Brain Transcriptome and Functional Dissection in Mouse Models. Cell Rep. 2020 07 14; 32(2):107908.
    View in: PubMed
    Score: 0.097
  17. Large-scale proteomic analysis of Alzheimer's disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation. Nat Med. 2020 05; 26(5):769-780.
    View in: PubMed
    Score: 0.095
  18. Changes in the detergent-insoluble brain proteome linked to amyloid and tau in Alzheimer's Disease progression. Proteomics. 2016 12; 16(23):3042-3053.
    View in: PubMed
    Score: 0.075
  19. Rare Functional Variant in TM2D3 is Associated with Late-Onset Alzheimer's Disease. PLoS Genet. 2016 Oct; 12(10):e1006327.
    View in: PubMed
    Score: 0.075
  20. NMNAT2:HSP90 Complex Mediates Proteostasis in Proteinopathies. PLoS Biol. 2016 06; 14(6):e1002472.
    View in: PubMed
    Score: 0.073
  21. GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer's disease. Neuron. 2013 Apr 24; 78(2):256-68.
    View in: PubMed
    Score: 0.058
  22. Genome-wide association study of the rate of cognitive decline in Alzheimer's disease. Alzheimers Dement. 2014 Jan; 10(1):45-52.
    View in: PubMed
    Score: 0.058
  23. Alzheimer disease susceptibility loci: evidence for a protein network under natural selection. Am J Hum Genet. 2012 Apr 06; 90(4):720-6.
    View in: PubMed
    Score: 0.054
  24. A coding variant in CR1 interacts with APOE-e4 to influence cognitive decline. Hum Mol Genet. 2012 May 15; 21(10):2377-88.
    View in: PubMed
    Score: 0.054
  25. The CETP I405V polymorphism is associated with an increased risk of Alzheimer's disease. Aging Cell. 2012 Apr; 11(2):228-33.
    View in: PubMed
    Score: 0.053
  26. A genome-wide scan for common variants affecting the rate of age-related cognitive decline. Neurobiol Aging. 2012 May; 33(5):1017.e1-15.
    View in: PubMed
    Score: 0.053
  27. Functional links between A? toxicity, endocytic trafficking, and Alzheimer's disease risk factors in yeast. Science. 2011 Dec 02; 334(6060):1241-5.
    View in: PubMed
    Score: 0.053
  28. CR1 is associated with amyloid plaque burden and age-related cognitive decline. Ann Neurol. 2011 Mar; 69(3):560-9.
    View in: PubMed
    Score: 0.050
  29. A putative Alzheimer's disease risk allele in PCK1 influences brain atrophy in multiple sclerosis. PLoS One. 2010 Nov 30; 5(11):e14169.
    View in: PubMed
    Score: 0.050
  30. Association of CR1, CLU and PICALM with Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals. Hum Mol Genet. 2010 Aug 15; 19(16):3295-301.
    View in: PubMed
    Score: 0.048
  31. Evidence for a common pathway linking neurodegenerative diseases. Nat Genet. 2009 Dec; 41(12):1261-2.
    View in: PubMed
    Score: 0.046
  32. Genetic modifiers of tauopathy in Drosophila. Genetics. 2003 Nov; 165(3):1233-42.
    View in: PubMed
    Score: 0.030
  33. Susceptibility to neurofibrillary tangles: role of the PTPRD locus and limited pleiotropy with other neuropathologies. Mol Psychiatry. 2018 06; 23(6):1521-1529.
    View in: PubMed
    Score: 0.019
  34. Common variants at 12q14 and 12q24 are associated with hippocampal volume. Nat Genet. 2012 Apr 15; 44(5):545-51.
    View in: PubMed
    Score: 0.014
  35. Genetic variation at CR1 increases risk of cerebral amyloid angiopathy. Neurology. 2012 Jan 31; 78(5):334-41.
    View in: PubMed
    Score: 0.013
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.