JOSHUA SHULMAN to Animals
This is a "connection" page, showing publications JOSHUA SHULMAN has written about Animals.
Connection Strength
0.698
-
Alzheimer's disease risk gene CD2AP is a dose-sensitive determinant of synaptic structure and plasticity. Hum Mol Genet. 2024 10 07; 33(20):1815-1832.
Score: 0.054
-
Tau polarizes an aging transcriptional signature to excitatory neurons and glia. Elife. 2023 May 23; 12.
Score: 0.049
-
Functional screening of lysosomal storage disorder genes identifies modifiers of alpha-synuclein neurotoxicity. PLoS Genet. 2023 05; 19(5):e1010760.
Score: 0.049
-
Integrated analysis of the aging brain transcriptome and proteome in tauopathy. Mol Neurodegener. 2020 09 29; 15(1):56.
Score: 0.041
-
Retromer subunit, VPS29, regulates synaptic transmission and is required for endolysosomal function in the aging brain. Elife. 2020 04 14; 9.
Score: 0.040
-
Tau-Mediated Disruption of the Spliceosome Triggers Cryptic RNA Splicing and Neurodegeneration in Alzheimer's Disease. Cell Rep. 2019 10 08; 29(2):301-316.e10.
Score: 0.038
-
cindr, the Drosophila Homolog of the CD2AP Alzheimer's Disease Risk Gene, Is Required for Synaptic Transmission and Proteostasis. Cell Rep. 2019 08 13; 28(7):1799-1813.e5.
Score: 0.038
-
Tau Activates Transposable Elements in Alzheimer's Disease. Cell Rep. 2018 06 05; 23(10):2874-2880.
Score: 0.035
-
Drosophila and genome-wide association studies: a review and resource for the functional dissection of human complex traits. Dis Model Mech. 2017 02 01; 10(2):77-88.
Score: 0.032
-
Uncoupling neuronal death and dysfunction in Drosophila models of neurodegenerative disease. Acta Neuropathol Commun. 2016 06 23; 4(1):62.
Score: 0.030
-
Drosophila and experimental neurology in the post-genomic era. Exp Neurol. 2015 Dec; 274(Pt A):4-13.
Score: 0.028
-
Functional screening in Drosophila identifies Alzheimer's disease susceptibility genes and implicates Tau-mediated mechanisms. Hum Mol Genet. 2014 Feb 15; 23(4):870-7.
Score: 0.025
-
Functional screening of Alzheimer pathology genome-wide association signals in Drosophila. Am J Hum Genet. 2011 Feb 11; 88(2):232-8.
Score: 0.021
-
Parkinson's disease: genetics and pathogenesis. Annu Rev Pathol. 2011; 6:193-222.
Score: 0.021
-
Tau is required for glial lipid droplet formation and resistance to neuronal oxidative stress. Nat Neurosci. 2024 Oct; 27(10):1918-1933.
Score: 0.013
-
Genetic modifiers of tauopathy in Drosophila. Genetics. 2003 Nov; 165(3):1233-42.
Score: 0.013
-
From fruit fly to bedside: translating lessons from Drosophila models of neurodegenerative disease. Curr Opin Neurol. 2003 Aug; 16(4):443-9.
Score: 0.012
-
Integration of transcriptome-wide association study with neuronal dysfunction assays provides functional genomics evidence for Parkinson's disease genes. Hum Mol Genet. 2023 01 27; 32(4):685-695.
Score: 0.012
-
TBK1 interacts with tau and enhances neurodegeneration in tauopathy. J Biol Chem. 2021 Jan-Jun; 296:100760.
Score: 0.011
-
Meta-Analysis of the Alzheimer's Disease Human Brain Transcriptome and Functional Dissection in Mouse Models. Cell Rep. 2020 07 14; 32(2):107908.
Score: 0.010
-
The Drosophila homolog of C. elegans PAR-1 organizes the oocyte cytoskeleton and directs oskar mRNA localization to the posterior pole. Cell. 2000 May 12; 101(4):377-88.
Score: 0.010
-
Large-scale proteomic analysis of Alzheimer's disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation. Nat Med. 2020 05; 26(5):769-780.
Score: 0.010
-
Pattern formation in single cells. Trends Cell Biol. 1999 Dec; 9(12):M60-4.
Score: 0.010
-
Genetic architecture of subcortical brain structures in 38,851 individuals. Nat Genet. 2019 11; 51(11):1624-1636.
Score: 0.010
-
A Portal to Visualize Transcriptome Profiles in Mouse Models of Neurological Disorders. Genes (Basel). 2019 09 26; 10(10).
Score: 0.010
-
A Druggable Genome Screen Identifies Modifiers of a-Synuclein Levels via a Tiered Cross-Species Validation Approach. J Neurosci. 2018 10 24; 38(43):9286-9301.
Score: 0.009
-
An ultra-fast and scalable quantification pipeline for transposable elements from next generation sequencing data. Pac Symp Biocomput. 2018; 23:168-179.
Score: 0.008
-
Discovery and functional prioritization of Parkinson's disease candidate genes from large-scale whole exome sequencing. Genome Biol. 2017 01 30; 18(1):22.
Score: 0.008
-
Rare Functional Variant in TM2D3 is Associated with Late-Onset Alzheimer's Disease. PLoS Genet. 2016 Oct; 12(10):e1006327.
Score: 0.008
-
NMNAT2:HSP90 Complex Mediates Proteostasis in Proteinopathies. PLoS Biol. 2016 06; 14(6):e1002472.
Score: 0.008
-
A mitocentric view of Parkinson's disease. Annu Rev Neurosci. 2014; 37:137-59.
Score: 0.007
-
Functional links between A? toxicity, endocytic trafficking, and Alzheimer's disease risk factors in yeast. Science. 2011 Dec 02; 334(6060):1241-5.
Score: 0.006
-
S/P and T/P phosphorylation is critical for tau neurotoxicity in Drosophila. J Neurosci Res. 2007 May 01; 85(6):1271-8.
Score: 0.004
-
TOR-mediated cell-cycle activation causes neurodegeneration in a Drosophila tauopathy model. Curr Biol. 2006 Feb 07; 16(3):230-41.
Score: 0.004
-
The role of PAR-1 in regulating the polarised microtubule cytoskeleton in the Drosophila follicular epithelium. Development. 2003 Sep; 130(17):3965-75.
Score: 0.003
-
Prickle mediates feedback amplification to generate asymmetric planar cell polarity signaling. Cell. 2002 May 03; 109(3):371-81.
Score: 0.003
-
Tauopathy in Drosophila: neurodegeneration without neurofibrillary tangles. Science. 2001 Jul 27; 293(5530):711-4.
Score: 0.003
-
PAR-1 is required for the maintenance of oocyte fate in Drosophila. Development. 2001 Apr; 128(7):1201-9.
Score: 0.003
-
The shc adaptor protein forms interdependent phosphotyrosine-mediated protein complexes in mast cells stimulated with interleukin 3. Blood. 2000 Jul 01; 96(1):132-8.
Score: 0.003
-
Differential recruitment of Dishevelled provides signaling specificity in the planar cell polarity and Wingless signaling pathways. Genes Dev. 1998 Aug 15; 12(16):2610-22.
Score: 0.002