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JOSHUA SHULMAN to Humans

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This is a "connection" page, showing publications JOSHUA SHULMAN has written about Humans.
JOSHUA SHULMAN
Connection Strength
0.608
Humans
  1. Alzheimer's disease risk gene CD2AP is a dose-sensitive determinant of synaptic structure and plasticity. Hum Mol Genet. 2024 10 07; 33(20):1815-1832.
    View in: PubMed
    Score: 0.025
  2. Tau polarizes an aging transcriptional signature to excitatory neurons and glia. Elife. 2023 May 23; 12.
    View in: PubMed
    Score: 0.023
  3. Functional screening of lysosomal storage disorder genes identifies modifiers of alpha-synuclein neurotoxicity. PLoS Genet. 2023 05; 19(5):e1010760.
    View in: PubMed
    Score: 0.023
  4. Genetics and Pathogenesis of Parkinson's Syndrome. Annu Rev Pathol. 2023 01 24; 18:95-121.
    View in: PubMed
    Score: 0.022
  5. Quantitative mobility measures complement the MDS-UPDRS for characterization of Parkinson's disease heterogeneity. Parkinsonism Relat Disord. 2021 03; 84:105-111.
    View in: PubMed
    Score: 0.020
  6. Integrated analysis of the aging brain transcriptome and proteome in tauopathy. Mol Neurodegener. 2020 09 29; 15(1):56.
    View in: PubMed
    Score: 0.019
  7. Tau-Mediated Disruption of the Spliceosome Triggers Cryptic RNA Splicing and Neurodegeneration in Alzheimer's Disease. Cell Rep. 2019 10 08; 29(2):301-316.e10.
    View in: PubMed
    Score: 0.018
  8. cindr, the Drosophila Homolog of the CD2AP Alzheimer's Disease Risk Gene, Is Required for Synaptic Transmission and Proteostasis. Cell Rep. 2019 08 13; 28(7):1799-1813.e5.
    View in: PubMed
    Score: 0.018
  9. Reply: Lysosomal storage disorder gene variants in multiple system atrophy. Brain. 2018 07 01; 141(7):e54.
    View in: PubMed
    Score: 0.016
  10. Tau Activates Transposable Elements in Alzheimer's Disease. Cell Rep. 2018 06 05; 23(10):2874-2880.
    View in: PubMed
    Score: 0.016
  11. Drosophila and genome-wide association studies: a review and resource for the functional dissection of human complex traits. Dis Model Mech. 2017 02 01; 10(2):77-88.
    View in: PubMed
    Score: 0.015
  12. Uncoupling neuronal death and dysfunction in Drosophila models of neurodegenerative disease. Acta Neuropathol Commun. 2016 06 23; 4(1):62.
    View in: PubMed
    Score: 0.014
  13. Drosophila and experimental neurology in the post-genomic era. Exp Neurol. 2015 Dec; 274(Pt A):4-13.
    View in: PubMed
    Score: 0.013
  14. Association of Parkinson disease risk loci with mild parkinsonian signs in older persons. JAMA Neurol. 2014 Apr; 71(4):429-35.
    View in: PubMed
    Score: 0.012
  15. Structural variation and the expanding genomic architecture of Parkinson disease. JAMA Neurol. 2013 Nov; 70(11):1355-6.
    View in: PubMed
    Score: 0.012
  16. Functional screening in Drosophila identifies Alzheimer's disease susceptibility genes and implicates Tau-mediated mechanisms. Hum Mol Genet. 2014 Feb 15; 23(4):870-7.
    View in: PubMed
    Score: 0.012
  17. Genetic susceptibility for Alzheimer disease neuritic plaque pathology. JAMA Neurol. 2013 Sep 01; 70(9):1150-7.
    View in: PubMed
    Score: 0.012
  18. Molecular mechanisms of cortical degeneration in Parkinson disease. Neurology. 2012 Oct 23; 79(17):1750-1.
    View in: PubMed
    Score: 0.011
  19. A coding variant in CR1 interacts with APOE-e4 to influence cognitive decline. Hum Mol Genet. 2012 May 15; 21(10):2377-88.
    View in: PubMed
    Score: 0.011
  20. Functional screening of Alzheimer pathology genome-wide association signals in Drosophila. Am J Hum Genet. 2011 Feb 11; 88(2):232-8.
    View in: PubMed
    Score: 0.010
  21. Parkinson's disease: genetics and pathogenesis. Annu Rev Pathol. 2011; 6:193-222.
    View in: PubMed
    Score: 0.010
  22. Intermediate phenotypes identify divergent pathways to Alzheimer's disease. PLoS One. 2010 Jun 21; 5(6):e11244.
    View in: PubMed
    Score: 0.009
  23. Evidence for a common pathway linking neurodegenerative diseases. Nat Genet. 2009 Dec; 41(12):1261-2.
    View in: PubMed
    Score: 0.009
  24. Dilemmas in diagnosing Alzheimer's disease: The peril and promise of self-fulfilling prophecies. J Alzheimers Dis. 2025 Jun; 105(3):736-739.
    View in: PubMed
    Score: 0.007
  25. Computational and functional prioritization identifies genes that rescue behavior and reduce tau protein in fly and human cell models of Alzheimer disease. Am J Hum Genet. 2025 May 01; 112(5):1081-1096.
    View in: PubMed
    Score: 0.007
  26. Racial Disparities in Parkinson Disease Clinical Phenotype, Management, and Genetics: Protocol for a Prospective Observational Study. JMIR Res Protoc. 2025 Apr 07; 14:e60587.
    View in: PubMed
    Score: 0.007
  27. Haploinsufficiency of ITSN1 is associated with a substantial increased risk of Parkinson's disease. Cell Rep. 2025 Mar 25; 44(3):115355.
    View in: PubMed
    Score: 0.007
  28. Emergency Department Patients with Para-Fluorofentanyl Overdose. J Emerg Med. 2025 May; 72:56-69.
    View in: PubMed
    Score: 0.006
  29. Trends in chlorine and chloramine gas exposures reported to United States poison centers. Clin Toxicol (Phila). 2024 Sep; 62(9):589-595.
    View in: PubMed
    Score: 0.006
  30. Prevalence and predictors of HIV among patients presenting to US emergency departments with opioid overdose. Drug Alcohol Depend. 2024 Nov 01; 264:112423.
    View in: PubMed
    Score: 0.006
  31. Tau is required for glial lipid droplet formation and resistance to neuronal oxidative stress. Nat Neurosci. 2024 Oct; 27(10):1918-1933.
    View in: PubMed
    Score: 0.006
  32. Surgical lessons from Shakespeare. Curr Surg. 2004 Jan-Feb; 61(1):96-7.
    View in: PubMed
    Score: 0.006
  33. Research Participants' Perspectives on Precision Diagnostics for Alzheimer's Disease. J Alzheimers Dis. 2024; 97(3):1261-1274.
    View in: PubMed
    Score: 0.006
  34. Parkinson's Disease and Other Alzheimer's Disease and Related Dementia Pathologies and the Progression of Parkinsonism in Older Adults. J Alzheimers Dis. 2024; 100(s1):S197-S209.
    View in: PubMed
    Score: 0.006
  35. From fruit fly to bedside: translating lessons from Drosophila models of neurodegenerative disease. Curr Opin Neurol. 2003 Aug; 16(4):443-9.
    View in: PubMed
    Score: 0.006
  36. Contribution of a positive psychology-based conceptual framework in reducing physician burnout and improving well-being: a systematic review. BMC Med Educ. 2021 Nov 25; 21(1):593.
    View in: PubMed
    Score: 0.005
  37. Frequency of Parkinsonism and Parkinson Disease in African Americans in the Chicago Community. J Gerontol A Biol Sci Med Sci. 2021 06 14; 76(7):1340-1345.
    View in: PubMed
    Score: 0.005
  38. TBK1 interacts with tau and enhances neurodegeneration in tauopathy. J Biol Chem. 2021 Jan-Jun; 296:100760.
    View in: PubMed
    Score: 0.005
  39. Proteomic Profiling of the Substantia Nigra to Identify Determinants of Lewy Body Pathology and Dopaminergic Neuronal Loss. J Proteome Res. 2021 05 07; 20(5):2266-2282.
    View in: PubMed
    Score: 0.005
  40. Quantifying cognitive resilience in Alzheimer's Disease: The Alzheimer's Disease Cognitive Resilience Score. PLoS One. 2020; 15(11):e0241707.
    View in: PubMed
    Score: 0.005
  41. Meta-Analysis of the Alzheimer's Disease Human Brain Transcriptome and Functional Dissection in Mouse Models. Cell Rep. 2020 07 14; 32(2):107908.
    View in: PubMed
    Score: 0.005
  42. Large-scale proteomic analysis of Alzheimer's disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation. Nat Med. 2020 05; 26(5):769-780.
    View in: PubMed
    Score: 0.005
  43. Genetic modifiers of risk and age at onset in GBA associated Parkinson's disease and Lewy body dementia. Brain. 2020 01 01; 143(1):234-248.
    View in: PubMed
    Score: 0.005
  44. Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies. Lancet Neurol. 2019 12; 18(12):1091-1102.
    View in: PubMed
    Score: 0.005
  45. Genetic architecture of subcortical brain structures in 38,851 individuals. Nat Genet. 2019 11; 51(11):1624-1636.
    View in: PubMed
    Score: 0.004
  46. Quantitative mobility metrics from a wearable sensor predict incident parkinsonism in older adults. Parkinsonism Relat Disord. 2019 08; 65:190-196.
    View in: PubMed
    Score: 0.004
  47. Parkinson's disease age at onset genome-wide association study: Defining heritability, genetic loci, and a-synuclein mechanisms. Mov Disord. 2019 06; 34(6):866-875.
    View in: PubMed
    Score: 0.004
  48. Progressive parkinsonism in older adults is related to the burden of mixed brain pathologies. Neurology. 2019 04 16; 92(16):e1821-e1830.
    View in: PubMed
    Score: 0.004
  49. Emerging links between pediatric lysosomal storage diseases and adult parkinsonism. Mov Disord. 2019 05; 34(5):614-624.
    View in: PubMed
    Score: 0.004
  50. A Druggable Genome Screen Identifies Modifiers of a-Synuclein Levels via a Tiered Cross-Species Validation Approach. J Neurosci. 2018 10 24; 38(43):9286-9301.
    View in: PubMed
    Score: 0.004
  51. An ultra-fast and scalable quantification pipeline for transposable elements from next generation sequencing data. Pac Symp Biocomput. 2018; 23:168-179.
    View in: PubMed
    Score: 0.004
  52. Excessive burden of lysosomal storage disorder gene variants in Parkinson's disease. Brain. 2017 12 01; 140(12):3191-3203.
    View in: PubMed
    Score: 0.004
  53. NeuroChip, an updated version of the NeuroX genotyping platform to rapidly screen for variants associated with neurological diseases. Neurobiol Aging. 2017 09; 57:247.e9-247.e13.
    View in: PubMed
    Score: 0.004
  54. Susceptibility to neurofibrillary tangles: role of the PTPRD locus and limited pleiotropy with other neuropathologies. Mol Psychiatry. 2018 06; 23(6):1521-1529.
    View in: PubMed
    Score: 0.004
  55. Discovery and functional prioritization of Parkinson's disease candidate genes from large-scale whole exome sequencing. Genome Biol. 2017 01 30; 18(1):22.
    View in: PubMed
    Score: 0.004
  56. Changes in the detergent-insoluble brain proteome linked to amyloid and tau in Alzheimer's Disease progression. Proteomics. 2016 12; 16(23):3042-3053.
    View in: PubMed
    Score: 0.004
  57. Rare Functional Variant in TM2D3 is Associated with Late-Onset Alzheimer's Disease. PLoS Genet. 2016 Oct; 12(10):e1006327.
    View in: PubMed
    Score: 0.004
  58. Genome-wide association study in essential tremor identifies three new loci. Brain. 2016 12; 139(Pt 12):3163-3169.
    View in: PubMed
    Score: 0.004
  59. Lack of evidence for a role of genetic variation in TMEM230 in the risk for Parkinson's disease in the Caucasian population. Neurobiol Aging. 2017 02; 50:167.e11-167.e13.
    View in: PubMed
    Score: 0.004
  60. Incident parkinsonism in older adults without Parkinson disease. Neurology. 2016 Sep 06; 87(10):1036-44.
    View in: PubMed
    Score: 0.004
  61. The Role of MAPT Haplotype H2 and Isoform 1N/4R in Parkinsonism of Older Adults. PLoS One. 2016; 11(7):e0157452.
    View in: PubMed
    Score: 0.004
  62. NMNAT2:HSP90 Complex Mediates Proteostasis in Proteinopathies. PLoS Biol. 2016 06; 14(6):e1002472.
    View in: PubMed
    Score: 0.004
  63. Whole-Exome Sequencing in Familial Parkinson Disease. JAMA Neurol. 2016 Jan; 73(1):68-75.
    View in: PubMed
    Score: 0.003
  64. Parkinsonism in Older Adults and Its Association With Adverse Health Outcomes and Neuropathology. J Gerontol A Biol Sci Med Sci. 2016 Apr; 71(4):549-56.
    View in: PubMed
    Score: 0.003
  65. GWAS for executive function and processing speed suggests involvement of the CADM2 gene. Mol Psychiatry. 2016 Feb; 21(2):189-197.
    View in: PubMed
    Score: 0.003
  66. Genome-wide studies of verbal declarative memory in nondemented older people: the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium. Biol Psychiatry. 2015 Apr 15; 77(8):749-63.
    View in: PubMed
    Score: 0.003
  67. A mitocentric view of Parkinson's disease. Annu Rev Neurosci. 2014; 37:137-59.
    View in: PubMed
    Score: 0.003
  68. Harm avoidance is associated with progression of parkinsonism in community-dwelling older adults: a prospective cohort study. BMC Geriatr. 2014 Apr 23; 14:54.
    View in: PubMed
    Score: 0.003
  69. Genetic susceptibility for ischemic infarction and arteriolosclerosis based on neuropathologic evaluations. Cerebrovasc Dis. 2013; 36(3):181-188.
    View in: PubMed
    Score: 0.003
  70. GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer's disease. Neuron. 2013 Apr 24; 78(2):256-68.
    View in: PubMed
    Score: 0.003
  71. Genome-wide association study of the rate of cognitive decline in Alzheimer's disease. Alzheimers Dement. 2014 Jan; 10(1):45-52.
    View in: PubMed
    Score: 0.003
  72. Heart transplantation for adults with congenital heart disease: results in the modern era. J Heart Lung Transplant. 2013 May; 32(5):499-504.
    View in: PubMed
    Score: 0.003
  73. A genome-wide association study of depressive symptoms. Biol Psychiatry. 2013 Apr 01; 73(7):667-78.
    View in: PubMed
    Score: 0.003
  74. Locus coeruleus neuron density and parkinsonism in older adults without Parkinson's disease. Mov Disord. 2012 Nov; 27(13):1625-31.
    View in: PubMed
    Score: 0.003
  75. A common polymorphism near PER1 and the timing of human behavioral rhythms. Ann Neurol. 2012 Sep; 72(3):324-34.
    View in: PubMed
    Score: 0.003
  76. Common variants at 12q14 and 12q24 are associated with hippocampal volume. Nat Genet. 2012 Apr 15; 44(5):545-51.
    View in: PubMed
    Score: 0.003
  77. Alzheimer disease susceptibility loci: evidence for a protein network under natural selection. Am J Hum Genet. 2012 Apr 06; 90(4):720-6.
    View in: PubMed
    Score: 0.003
  78. Nigral pathology and parkinsonian signs in elders without Parkinson disease. Ann Neurol. 2012 Feb; 71(2):258-66.
    View in: PubMed
    Score: 0.003
  79. Genetic variation at CR1 increases risk of cerebral amyloid angiopathy. Neurology. 2012 Jan 31; 78(5):334-41.
    View in: PubMed
    Score: 0.003
  80. The CETP I405V polymorphism is associated with an increased risk of Alzheimer's disease. Aging Cell. 2012 Apr; 11(2):228-33.
    View in: PubMed
    Score: 0.003
  81. A genome-wide scan for common variants affecting the rate of age-related cognitive decline. Neurobiol Aging. 2012 May; 33(5):1017.e1-15.
    View in: PubMed
    Score: 0.003
  82. Functional links between A? toxicity, endocytic trafficking, and Alzheimer's disease risk factors in yeast. Science. 2011 Dec 02; 334(6060):1241-5.
    View in: PubMed
    Score: 0.003
  83. CR1 is associated with amyloid plaque burden and age-related cognitive decline. Ann Neurol. 2011 Mar; 69(3):560-9.
    View in: PubMed
    Score: 0.002
  84. A putative Alzheimer's disease risk allele in PCK1 influences brain atrophy in multiple sclerosis. PLoS One. 2010 Nov 30; 5(11):e14169.
    View in: PubMed
    Score: 0.002
  85. Association of CR1, CLU and PICALM with Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals. Hum Mol Genet. 2010 Aug 15; 19(16):3295-301.
    View in: PubMed
    Score: 0.002
  86. Ramsay Hunt syndrome in a patient with metastatic lung cancer to brain. J Neurooncol. 2008 Jan; 86(1):55-6.
    View in: PubMed
    Score: 0.002
  87. Prickle mediates feedback amplification to generate asymmetric planar cell polarity signaling. Cell. 2002 May 03; 109(3):371-81.
    View in: PubMed
    Score: 0.001
  88. Tauopathy in Drosophila: neurodegeneration without neurofibrillary tangles. Science. 2001 Jul 27; 293(5530):711-4.
    View in: PubMed
    Score: 0.001
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.