ROLANDORUMBAUTROLANDO RUMBAUT29.70508570000000-95.40180870000000229RUMBAUT, ROLANDOProfessorprns:coAuthorOfcoauthor ofprns:endDateend dateFaculty Rankprns:fullNamefull nameprns:grantAwardedBygrant awarded byprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:physicalNeighborOfphysical neighborprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:principalInvestigatorNameprincipal investigator nameprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:startDatestart dateprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressvivo:address1address line 1vivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provinceAgreementvivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentDivisionGrantvivo:hasResearchArearesearch areasvivo:hasResearcherRoleresearch activitiesvivo:hrJobTitleHR job titleInformation Resourcevivo:linkAnchorTextlink anchor textvivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:personInPositionpositionsPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titleResearcher Rolevivo:researcherRoleOfresearcher role ofRolevivo:roleContributesTocontributes tovivo:sponsorAwardIdsponsor award idURLLinkvivo:webpagewebpagerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonAuthorship 156291825330904Khatlani T, Pradhan S, Da Q, Gushiken FC, Bergeron AL, Langlois KW, Molkentin JD, Rumbaut RE, Vijayan KVJournal of thrombosis and haemostasis : JTHThe ? isoform of the catalytic subunit of protein phosphatase 2B restrains platelet function by suppressing outside-in aII b ?3 integrin signaling. J Thromb Haemost. 2014 Dec; 12(12):2089-101.J Thromb Haemost2014-11-15T00:00:002014The ? isoform of the catalytic subunit of protein phosphatase 2B restrains platelet function by suppressing outside-in aII b ?3 integrin signaling.Authorship 831791Authorship 87251Authorship 912079Authorship 969414Authorship 962057Authorship 1099007Authorship 199138Authorship 16098614Authorship 162178625574801Casal RF, Lazarus DR, Kuhl K, Nogueras-Gonz?lez G, Perusich S, Green LK, Ost DE, Sarkiss M, Jimenez CA, Eapen GA, Morice RC, Cornwell L, Austria S, Sharafkanneh A, Rumbaut RE, Grosu H, Kheradmand FAmerican journal of respiratory and critical care medicineRandomized trial of endobronchial ultrasound-guided transbronchial needle aspiration under general anesthesia versus moderate sedation. Am J Respir Crit Care Med. 2015 Apr 01; 191(7):796-803.Am J Respir Crit Care Med2015-04-01T00:00:002015Randomized trial of endobronchial ultrasound-guided transbronchial needle aspiration under general anesthesia versus moderate sedation.25775402Lam FW, Phillips J, Landry P, Magadi S, Smith CW, Rumbaut RE, Burns ARPloS onePlatelet recruitment promotes keratocyte repopulation following corneal epithelial abrasion in the mouse. PLoS One. 2015; 10(3):e0118950.PLoS One2015-03-16T00:00:002015Platelet recruitment promotes keratocyte repopulation following corneal epithelial abrasion in the mouse.Authorship 322803Authorship 470631Authorship 626062Authorship 686276Authorship 7337048296805Rumbaut RE, Kroll MH, Gyorkey F, Schafer AIAmerican journal of hematologyAcquired platelet storage pool deficiency due to severe valvular disease corrected by prosthetic valve replacement. Am J Hematol. 1994 Mar; 45(3):272-3.Am J Hematol1994-03-01T00:00:001994Acquired platelet storage pool deficiency due to severe valvular disease corrected by prosthetic valve replacement.9887048Rumbaut RE, Harris NR, Sial AJ, Huxley VH, Granger DNThe American journal of physiologyLeakage responses to L-NAME differ with the fluorescent dye used to label albumin. Am J Physiol. 1999 01; 276(1):H333-9.Am J Physiol1999-01-01T00:00:001999Leakage responses to L-NAME differ with the fluorescent dye used to label albumin.Authorship 3008742Authorship 304614326140718Lam FW, Vijayan KV, Rumbaut REComprehensive PhysiologyPlatelets and Their Interactions with Other Immune Cells. Compr Physiol. 2015 Jul 01; 5(3):1265-80.Compr Physiol2015-07-01T00:00:002015Platelets and Their Interactions with Other Immune Cells.26450954Lam FW, Rumbaut REBloodPlatelets mediate acetaminophen hepatotoxicity. Blood. 2015 Oct 08; 126(15):1738-9.Blood2015-10-08T00:00:002015Platelets mediate acetaminophen hepatotoxicity.7200 CAMBRIDGEHouston, 77030TX10501094Rumbaut RE, Sial AJMicrocirculation (New York, N.Y. : 1994)Differential phototoxicity of fluorescent dye-labeled albumin conjugates. Microcirculation. 1999 Sep; 6(3):205-13.Microcirculation1999-09-01T00:00:001999Differential phototoxicity of fluorescent dye-labeled albumin conjugates.12080415Harris NR, Whitt SP, Zilberberg J, Alexander JS, Rumbaut REMicrocirculation (New York, N.Y. : 1994)Extravascular transport of fluorescently labeled albumins in the rat mesentery. Microcirculation. 2002 Jul; 9(3):177-87.Microcirculation2002-07-01T00:00:002002Extravascular transport of fluorescently labeled albumins in the rat mesentery.11009493Rumbaut RE, Wang J, Huxley VHAmerican journal of physiology. Heart and circulatory physiologyDifferential effects of L-NAME on rat venular hydraulic conductivity. Am J Physiol Heart Circ Physiol. 2000 Oct; 279(4):H2017-23.Am J Physiol Heart Circ Physiol2000-10-01T00:00:002000Differential effects of L-NAME on rat venular hydraulic conductivity.12700589Bingaman S, Huxley VH, Rumbaut REMicrocirculation (New York, N.Y. : 1994)Fluorescent dyes modify properties of proteins used in microvascular research. Microcirculation. 2003 Apr; 10(2):221-31.Microcirculation2003-04-01T00:00:002003Fluorescent dyes modify properties of proteins used in microvascular research.27013650Lam FW, Cruz MA, Parikh K, Rumbaut REHaematologicaHistones stimulate von Willebrand factor release in vitro and in vivo. Haematologica. 2016 07; 101(7):e277-9.Haematologica2016-03-24T00:00:002016Histones stimulate von Willebrand factor release in vitro and in vivo.74Professor10Assistant Professor33Clinical Professor14Associate Professor78Professor Emeritus6Adjunct Professor16210565Jiang X, Yang F, Tan H, Liao D, Bryan RM, Randhawa JK, Rumbaut RE, Durante W, Schafer AI, Yang X, Wang HArteriosclerosis, thrombosis, and vascular biologyHyperhomocystinemia impairs endothelial function and eNOS activity via PKC activation. Arterioscler Thromb Vasc Biol. 2005 Dec; 25(12):2515-21.Arterioscler Thromb Vasc Biol2005-10-06T00:00:002005Hyperhomocystinemia impairs endothelial function and eNOS activity via PKC activation.16284241Rumbaut RE, Bellera RV, Randhawa JK, Shrimpton CN, Dasgupta SK, Dong JF, Burns ARAmerican journal of physiology. Heart and circulatory physiologyEndotoxin enhances microvascular thrombosis in mouse cremaster venules via a TLR4-dependent, neutrophil-independent mechanism. Am J Physiol Heart Circ Physiol. 2006 Apr; 290(4):H1671-9.Am J Physiol Heart Circ Physiol2005-11-11T00:00:002005Endotoxin enhances microvascular thrombosis in mouse cremaster venules via a TLR4-dependent, neutrophil-independent mechanism.Authorship 3228764Authorship 326962527627652Dasgupta SK, Le A, Da Q, Cruz M, Rumbaut RE, Thiagarajan PPloS oneWdr1-Dependent Actin Reorganization in Platelet Activation. PLoS One. 2016; 11(9):e0162897.PLoS One2016-09-14T00:00:002016Wdr1-Dependent Actin Reorganization in Platelet Activation.17675580Li Z, Burns AR, Rumbaut RE, Smith CWThe American journal of pathologygamma delta T cells are necessary for platelet and neutrophil accumulation in limbal vessels and efficient epithelial repair after corneal abrasion. Am J Pathol. 2007 Sep; 171(3):838-45.Am J Pathol2007-08-03T00:00:002007gamma delta T cells are necessary for platelet and neutrophil accumulation in limbal vessels and efficient epithelial repair after corneal abrasion.17720767Burns AR, Zheng Z, Soubra SH, Chen J, Rumbaut REAmerican journal of physiology. Heart and circulatory physiologyTransendothelial flow inhibits neutrophil transmigration through a nitric oxide-dependent mechanism: potential role for cleft shear stress. Am J Physiol Heart Circ Physiol. 2007 Nov; 293(5):H2904-10.Am J Physiol Heart Circ Physiol2007-08-24T00:00:002007Transendothelial flow inhibits neutrophil transmigration through a nitric oxide-dependent mechanism: potential role for cleft shear stress.15280078Rumbaut RE, Randhawa JK, Smith CW, Burns ARMicrocirculation (New York, N.Y. : 1994)Mouse cremaster venules are predisposed to light/dye-induced thrombosis independent of wall shear rate, CD18, ICAM-1, or P-selectin. Microcirculation. 2004 Apr-May; 11(3):239-47.Microcirculation2004-04-01T00:00:002004Mouse cremaster venules are predisposed to light/dye-induced thrombosis independent of wall shear rate, CD18, ICAM-1, or P-selectin.18327404Guchhait P, Shrimpton CN, Honke K, Rumbaut RE, Lopez JA, Thiagarajan PThrombosis and haemostasisEffect of an anti-sulfatide single-chain antibody probe on platelet function. Thromb Haemost. 2008 Mar; 99(3):552-7.Thromb Haemost2008-03-01T00:00:002008Effect of an anti-sulfatide single-chain antibody probe on platelet function.15814432Rumbaut REMicrocirculation (New York, N.Y. : 1994)Platelet-microvessel interactions. Microcirculation. 2005 Apr-May; 12(3):233-4.Microcirculation2005-04-01T00:00:002005Platelet-microvessel interactions.15814435Rumbaut RE, Slaff DW, Burns ARMicrocirculation (New York, N.Y. : 1994)Microvascular thrombosis models in venules and arterioles in vivo. Microcirculation. 2005 Apr-May; 12(3):259-74.Microcirculation2005-04-01T00:00:002005Microvascular thrombosis models in venules and arterioles in vivo.19608878Byeseda SE, Burns AR, Dieffenbaugher S, Rumbaut RE, Smith CW, Li ZThe American journal of pathologyICAM-1 is necessary for epithelial recruitment of gammadelta T cells and efficient corneal wound healing. Am J Pathol. 2009 Aug; 175(2):571-9.Am J Pathol2009-07-16T00:00:002009ICAM-1 is necessary for epithelial recruitment of gammadelta T cells and efficient corneal wound healing.20345726Patel KN, Soubra SH, Lam FW, Rodriguez MA, Rumbaut REJournal of thrombosis and haemostasis : JTHPolymicrobial sepsis and endotoxemia promote microvascular thrombosis via distinct mechanisms. J Thromb Haemost. 2010 Jun; 8(6):1403-9.J Thromb Haemost2010-03-12T00:00:002010Polymicrobial sepsis and endotoxemia promote microvascular thrombosis via distinct mechanisms.16162778Dhillon SS, Mahadevan K, Bandi V, Zheng Z, Smith CW, Rumbaut REChestNeutrophils, nitric oxide, and microvascular permeability in severe sepsis. Chest. 2005 Sep; 128(3):1706-12.Chest2005-09-01T00:00:002005Neutrophils, nitric oxide, and microvascular permeability in severe sepsis.21356362Li Z, Burns AR, Han L, Rumbaut RE, Smith CWThe American journal of pathologyIL-17 and VEGF are necessary for efficient corneal nerve regeneration. Am J Pathol. 2011 Mar; 178(3):1106-16.Am J Pathol2011-03-01T00:00:002011IL-17 and VEGF are necessary for efficient corneal nerve regeneration.22388320Dasgupta SK, Le A, Chavakis T, Rumbaut RE, Thiagarajan PCirculationDevelopmental endothelial locus-1 (Del-1) mediates clearance of platelet microparticles by the endothelium. Circulation. 2012 Apr 03; 125(13):1664-72.Circulation2012-03-02T00:00:002012Developmental endothelial locus-1 (Del-1) mediates clearance of platelet microparticles by the endothelium.17065490Li Z, Rumbaut RE, Burns AR, Smith CWInvestigative ophthalmology & visual sciencePlatelet response to corneal abrasion is necessary for acute inflammation and efficient re-epithelialization. Invest Ophthalmol Vis Sci. 2006 Nov; 47(11):4794-802.Invest Ophthalmol Vis Sci2006-11-01T00:00:002006Platelet response to corneal abrasion is necessary for acute inflammation and efficient re-epithelialization.17512574Sorg H, Hoffmann JN, Rumbaut RE, Menger MD, Lindenblatt N, Vollmar BThrombosis researchEfficacy of antithrombin in the prevention of microvascular thrombosis during endotoxemia: an intravital microscopic study. Thromb Res. 2007; 121(2):241-8.Thromb Res2007-05-18T00:00:002007Efficacy of antithrombin in the prevention of microvascular thrombosis during endotoxemia: an intravital microscopic study.18032520Rumbaut RE, Mirkovic DAmerican journal of physiology. Heart and circulatory physiologyMagnetic therapy for edema in inflammation: a physiological assessment. Am J Physiol Heart Circ Physiol. 2008 Jan; 294(1):H19-20.Am J Physiol Heart Circ Physiol2007-11-21T00:00:002007Magnetic therapy for edema in inflammation: a physiological assessment.18802014Patel KN, Soubra SH, Bellera RV, Dong JF, McMullen CA, Burns AR, Rumbaut REArteriosclerosis, thrombosis, and vascular biologyDifferential role of von Willebrand factor and P-selectin on microvascular thrombosis in endotoxemia. Arterioscler Thromb Vasc Biol. 2008 Dec; 28(12):2225-2230.Arterioscler Thromb Vasc Biol2008-09-18T00:00:002008Differential role of von Willebrand factor and P-selectin on microvascular thrombosis in endotoxemia.19023116Dasgupta SK, Abdel-Monem H, Niravath P, Le A, Bellera RV, Langlois K, Nagata S, Rumbaut RE, Thiagarajan PBloodLactadherin and clearance of platelet-derived microvesicles. Blood. 2009 Feb 05; 113(6):1332-9.Blood2008-11-20T00:00:002008Lactadherin and clearance of platelet-derived microvesicles.19291167Gushiken FC, Han H, Li J, Rumbaut RE, Afshar-Kharghan VJournal of thrombosis and haemostasis : JTHAbnormal platelet function in C3-deficient mice. J Thromb Haemost. 2009 May; 7(5):865-70.J Thromb Haemost2009-03-05T00:00:002009Abnormal platelet function in C3-deficient mice.20016849Gushiken FC, Hyojeong H, Pradhan S, Langlois KW, Alrehani N, Cruz MA, Rumbaut RE, Vijayan KVPloS oneThe catalytic subunit of protein phosphatase 1 gamma regulates thrombin-induced murine platelet alpha(IIb)beta(3) function. PLoS One. 2009 Dec 15; 4(12):e8304.PLoS One2009-12-15T00:00:002009The catalytic subunit of protein phosphatase 1 gamma regulates thrombin-induced murine platelet alpha(IIb)beta(3) function.21169400Lam FW, Burns AR, Smith CW, Rumbaut REAmerican journal of physiology. Heart and circulatory physiologyPlatelets enhance neutrophil transendothelial migration via P-selectin glycoprotein ligand-1. Am J Physiol Heart Circ Physiol. 2011 Feb; 300(2):H468-75.Am J Physiol Heart Circ Physiol2010-12-17T00:00:002010Platelets enhance neutrophil transendothelial migration via P-selectin glycoprotein ligand-1.20807601Godin B, Driessen WH, Proneth B, Lee SY, Srinivasan S, Rumbaut R, Arap W, Pasqualini R, Ferrari M, Decuzzi PAdvances in geneticsAn integrated approach for the rational design of nanovectors for biomedical imaging and therapy. Adv Genet. 2010; 69:31-64.Adv Genet2010-01-01T00:00:002010An integrated approach for the rational design of nanovectors for biomedical imaging and therapy.23266857Zhou Z, Gushiken FC, Bolgiano D, Salsbery BJ, Aghakasiri N, Jing N, Wu X, Vijayan KV, Rumbaut RE, Adachi R, Lopez JA, Dong JFCirculationSignal transducer and activator of transcription 3 (STAT3) regulates collagen-induced platelet aggregation independently of its transcription factor activity. Circulation. 2013 Jan 29; 127(4):476-485.Circulation2012-12-24T00:00:002012Signal transducer and activator of transcription 3 (STAT3) regulates collagen-induced platelet aggregation independently of its transcription factor activity.7539589Rumbaut RE, McKay MK, Huxley VHThe American journal of physiologyCapillary hydraulic conductivity is decreased by nitric oxide synthase inhibition. Am J Physiol. 1995 May; 268(5 Pt 2):H1856-61.Am J Physiol1995-05-01T00:00:001995Capillary hydraulic conductivity is decreased by nitric oxide synthase inhibition.8653939King PD, Rumbaut R, Sanchez CDigestive diseases (Basel, Switzerland)Pulmonary manifestations of chronic liver disease. Dig Dis. 1996 Mar-Apr; 14(2):73-82.Dig Dis1996-03-01T00:00:001996Pulmonary manifestations of chronic liver disease.Authorship 103722511022981Huxley VH, Rumbaut REClinical and experimental pharmacology & physiologyThe microvasculature as a dynamic regulator of volume and solute exchange. Clin Exp Pharmacol Physiol. 2000 Oct; 27(10):847-54.Clin Exp Pharmacol Physiol2000-10-01T00:00:002000The microvasculature as a dynamic regulator of volume and solute exchange.28533893Royse KE, Chen L, Berger DH, Ittmann MM, El-Serag HB, Balentine CJ, Graham DY, Richardson PA, Rumbaut RE, Shen X, White DL, Jiao LInternational journal of molecular epidemiology and geneticsExpression of pattern recognition receptor genes and mortality in patients with colorectal adenocarcinoma. Int J Mol Epidemiol Genet. 2017; 8(2):8-18.Int J Mol Epidemiol Genet2017-04-15T00:00:002017Expression of pattern recognition receptor genes and mortality in patients with colorectal adenocarcinoma.16303946Andrade FH, McMullen CA, Rumbaut REInvestigative ophthalmology & visual scienceMitochondria are fast Ca2+ sinks in rat extraocular muscles: a novel regulatory influence on contractile function and metabolism. Invest Ophthalmol Vis Sci. 2005 Dec; 46(12):4541-7.Invest Ophthalmol Vis Sci2005-12-01T00:00:002005Mitochondria are fast Ca2+ sinks in rat extraocular muscles: a novel regulatory influence on contractile function and metabolism.22911769Stark RJ, Aghakasiri N, Rumbaut REPloS onePlatelet-derived Toll-like receptor 4 (Tlr-4) is sufficient to promote microvascular thrombosis in endotoxemia. PLoS One. 2012; 7(7):e41254.PLoS One2012-07-20T00:00:002012Platelet-derived Toll-like receptor 4 (Tlr-4) is sufficient to promote microvascular thrombosis in endotoxemia.Authorship 8789309Authorship 8822814Authorship 885685829674495Cardenas EI, Breaux K, Da Q, Flores JR, Ramos MA, Tuvim MJ, Burns AR, Rumbaut RE, Adachi RHaematologicaPlatelet Munc13-4 regulates hemostasis, thrombosis and airway inflammation. Haematologica. 2018 07; 103(7):1235-1244.Haematologica2018-04-19T00:00:002018Platelet Munc13-4 regulates hemostasis, thrombosis and airway inflammation.29701894Da Q, Derry PJ, Lam FW, Rumbaut REMicrocirculation (New York, N.Y. : 1994)Fluorescent labeling of endogenous platelets for intravital microscopy: Effects on platelet function. Microcirculation. 2018 08; 25(6):e12457.Microcirculation2018-05-30T00:00:002018Fluorescent labeling of endogenous platelets for intravital microscopy: Effects on platelet function.true1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1Assistant ProfessorAssistant Professor2ProfessorProfessortrue1Associate ProfessorAssociate Professortrue1Assistant ProfessorAssistant ProfessorD009504Anatomy4038310.703625NeutrophilsD014842Disorders30610.929949von Willebrand DiseasesAuthorship 1083204D014699Anatomy14270.982466VenulesAuthorship 940370930696774Cardenas EI, Gonzalez R, Breaux K, Da Q, Gutierrez BA, Ramos MA, Cardenas RA, Burns AR, Rumbaut RE, Adachi RThe Journal of biological chemistryMunc18-2, but not Munc18-1 or Munc18-3, regulates platelet exocytosis, hemostasis, and thrombosis. J Biol Chem. 2019 03 29; 294(13):4784-4792.J Biol Chem2019-01-29T00:00:002019Munc18-2, but not Munc18-1 or Munc18-3, regulates platelet exocytosis, hemostasis, and thrombosis.D013927AnatomyDisorders3747820.603758ThrombosisD001792Anatomy2817310.683535Blood Platelets2025-03-31NIHRUMBAUT, ROLANDO E2016-04-01Mechanisms of microvascular thrombosis in inflammationI01BX0025512023-07-31NIHCRUZ, MIGUEL ANGEL;RUMBAUT, ROLANDO E2018-08-01Collaborative Research Training in Thrombosis and InflammationT32HL1394252000-08-31NIHRUMBAUT, ROLANDO E1997-09-01REGULATION OF MICROVASCULAR PERMEABILITY BY NITRIC OXIDEK08HL0037382021-11-30NIHRUMBAUT, ROLANDO E2008-01-01Ocular Surface Injury: Inflammatory Cascade and Healing of Corneal WoundsR01EY0182392014-09-30NIHRUMBAUT, ROLANDO E2009-10-01The complement system links platelet activation to inflammationI01BX0005502012-03-31NIHRUMBAUT, ROLANDO E2006-04-01MECHANISMS OF MICROVASCULAR THROMBOSIS IN ENDOTOXEMIAR01HL0793682016-09-30NIHRUMBAUT, ROLANDO E2016-05-01LAMb Request for Laboratory Animal Major Vivarium EquipmentIS1BX0030822017-09-30NIHRUMBAUT, ROLANDO E2017-01-01ShEEP Request for Super Resolution Laser Scanning Confocal Microscopy SystemIS1BX0039672019-01-31NIHRUMBAUT, ROLANDO E2013-02-01Platelets and Their Microparticles in the Inflamed MicrocirculationR01HL1165242006-03-31NIHRUMBAUT, ROLANDO E2001-07-01Regulation of microvascular permeability by nitric oxideR01HL064721Principal InvestigatorPrincipal InvestigatorPrincipal InvestigatorPrincipal InvestigatorPrincipal InvestigatorPrincipal InvestigatorPrincipal InvestigatorPrincipal InvestigatorPrincipal InvestigatorDepartment of MedicineDepartment of OphthalmologyDepartment of PediatricsDepartment of Pathology & ImmunologyMedicine-CardiologyMedicine-General Med/VAMCMedicine-Hematology & OncologyMedicine-PulmonaryMedicine-Thrombosis ResearchOphthalmologyPathologyPediatrics-Critical CarePediatrics-Leukocyte BiologyBaylor College of MedicineKAMALHIRANIKAMAL HIRANI29.70508570000000-95.401808700000001173HIRANI, KAMALAssistant ProfessorELIZABETHGUYELIZABETH GUY29.70508570000000-95.40180870000000140GUY, ELIZABETHAssistant ProfessorSTEPHENPFLUGFELDERSTEPHEN PFLUGFELDER29.70508570000000-95.40180870000000167PFLUGFELDER, STEPHENProfessorROBERTSOLISROBERT SOLIS29.70508570000000-95.401808700000002521SOLIS, ROBERTClinical ProfessorAMIRSHARAFKHANEHAMIR SHARAFKHANEH29.70508570000000-95.401808700000002082SHARAFKHANEH, AMIRProfessorMIGUELCRUZMIGUEL CRUZ0.000000000000000.00000000000000235CRUZ, MIGUELProfessor4.319020.00528378332research areas3.896680.017373743coauthor of43.80067.9143760similar to1167selected publicationsNEALKLEIMANNEAL KLEIMAN29.70991060000000-95.401413900000002919KLEIMAN, NEALAdjunct ProfessorJOELMOAKEJOEL MOAKE29.70508570000000-95.401808700000003057MOAKE, JOELProfessor EmeritusPrincipal InvestigatorCHARLIELANCHARLIE LAN29.70508570000000-95.40180870000000460LAN, CHARLIEAssociate ProfessorFONGLAMFONG LAM0.000000000000000.000000000000003477LAM, FONGAssociate ProfessorPERUMALTHIAGARAJANPERUMAL THIAGARAJAN0.000000000000000.00000000000000396THIAGARAJAN, PERUMALProfessorSWAPANDASGUPTASWAPAN DASGUPTA0.000000000000000.00000000000000571DASGUPTA, SWAPANAssistant Professor2019-09-30NIHRUMBAUT, ROLANDO E2019-01-01ShEEP request for high-resolution flow cytometry systemIS1BX004798Principal InvestigatorAuthorship 126259623673386Lam FW, Cruz MA, Leung HC, Parikh KS, Smith CW, Rumbaut REThrombosis researchHistone induced platelet aggregation is inhibited by normal albumin. Thromb Res. 2013 Jul; 132(1):69-76.Thromb Res2013-05-11T00:00:002013Histone induced platelet aggregation is inhibited by normal albumin.true1Associate ProfessorAssociate ProfessorAuthorship 952181631319467Osae EA, Steven P, Redfern R, Hanlon S, Smith CW, Rumbaut RE, Burns ARInternational journal of molecular sciencesDyslipidemia and Meibomian Gland Dysfunction: Utility of Lipidomics and Experimental Prospects with a Diet-Induced Obesity Mouse Model. Int J Mol Sci. 2019 Jul 17; 20(14).Int J Mol Sci2019-07-17T00:00:002019Dyslipidemia and Meibomian Gland Dysfunction: Utility of Lipidomics and Experimental Prospects with a Diet-Induced Obesity Mouse Model.true1ProfessorProfessorAuthorship 960944831721785Courson JA, Smith I, Do T, Landry PT, Hargrave A, Behzad AR, Hanlon SD, Rumbaut RE, Smith CW, Burns ARPloS oneSerial block-face scanning electron microscopy reveals neuronal-epithelial cell fusion in the mouse cornea. PLoS One. 2019; 14(11):e0224434.PLoS One2019-11-13T00:00:002019Serial block-face scanning electron microscopy reveals neuronal-epithelial cell fusion in the mouse cornea.Authorship 9625712Authorship 96257211476967Harris NR, Rumbaut REPathophysiology : the official journal of the International Society for PathophysiologyAge-related responses of the microcirculation to ischemia-reperfusion and inflammation. Pathophysiology. 2001 Aug; 8(1):1-10.Pathophysiology2001-08-01T00:00:002001Age-related responses of the microcirculation to ischemia-reperfusion and inflammation.Rumbaut RE, Thiagarajan PPlatelet-Vessel Wall Interactions in Hemostasis and ThrombosisIntegrated Systems Physiology: from Molecule to Function to Disease. Platelet-Vessel Wall Interactions in Hemostasis and Thrombosis. 2010; 1-67.2010-01-01T00:00:002010Integrated Systems Physiology: from Molecule to Function to Disease71Postdoc Fellows and AssociatesPostDoctrue1Assistant ProfessorAssistant Professor32259201Valladolid C, Martinez-Vargas M, Sekhar N, Lam F, Brown C, Palzkill T, Tischer A, Auton M, Vijayan KV, Rumbaut RE, Nguyen TC, Cruz MABlood advancesModulating the rate of fibrin formation and clot structure attenuates microvascular thrombosis in systemic inflammation. Blood Adv. 2020 04 14; 4(7):1340-1349.Blood Adv2020-04-14T00:00:002020Modulating the rate of fibrin formation and clot structure attenuates microvascular thrombosis in systemic inflammation.Authorship 98664910Authorship 990236432454092Bray MA, Sartain SE, Gollamudi J, Rumbaut RETranslational research : the journal of laboratory and clinical medicineMicrovascular thrombosis: experimental and clinical implications. Transl Res. 2020 11; 225:105-130.Transl Res2020-05-23T00:00:002020Microvascular thrombosis: experimental and clinical implications.Authorship 998314932886728Hargrave A, Courson JA, Pham V, Landry P, Magadi S, Shankar P, Hanlon S, Das A, Rumbaut RE, Smith CW, Burns ARPloS oneCorneal dysfunction precedes the onset of hyperglycemia in a mouse model of diet-induced obesity. PLoS One. 2020; 15(9):e0238750.PLoS One2020-09-04T00:00:002020Corneal dysfunction precedes the onset of hyperglycemia in a mouse model of diet-induced obesity.https://www.bcm.edu/research/centers/translational-research-inflammatory-diseasesCenter for Translational Research on Inflammatory DiseasesAuthorship 1124071Authorship 1003503633099176Courson JA, Hanlon SD, Bray MA, Lam FW, Burns AR, Rumbaut REThrombosis researchSerial block-face scanning electron microscopy: A provocative technique to define 3-dimensional ultrastructure of microvascular thrombosis. Thromb Res. 2020 12; 196:519-522.Thromb Res2020-10-12T00:00:002020Serial block-face scanning electron microscopy: A provocative technique to define 3-dimensional ultrastructure of microvascular thrombosis.Authorship 1005642933233559Osae EA, Bullock T, Chintapalati M, Brodesser S, Hanlon S, Redfern R, Steven P, Smith CW, Rumbaut RE, Burns ARInternational journal of molecular sciencesObese Mice with Dyslipidemia Exhibit Meibomian Gland Hypertrophy and Alterations in Meibum Composition and Aqueous Tear Production. Int J Mol Sci. 2020 Nov 20; 21(22).Int J Mol Sci2020-11-20T00:00:002020Obese Mice with Dyslipidemia Exhibit Meibomian Gland Hypertrophy and Alterations in Meibum Composition and Aqueous Tear Production.Authorship 1006583433290884Hubbard WB, Dong JF, Cruz MA, Rumbaut REThrombosis researchLinks between thrombosis and inflammation in traumatic brain injury. Thromb Res. 2021 02; 198:62-71.Thromb Res2020-11-25T00:00:002020Links between thrombosis and inflammation in traumatic brain injury.Authorship 1016165733843931Courson JA, Landry PT, Do T, Spehlmann E, Lafontant PJ, Patel N, Rumbaut RE, Burns ARJournal of visualized experiments : JoVESerial Block-Face Scanning Electron Microscopy (SBF-SEM) of Biological Tissue Samples. J Vis Exp. 2021 03 26; (169).J Vis Exp2021-03-26T00:00:002021Serial Block-Face Scanning Electron Microscopy (SBF-SEM) of Biological Tissue Samples.true1Postdoc Fellows and AssociatesPostdoc Fellows and AssociatesJustinCoursonJustin Courson16789Courson, JustinPostdoc Fellows and AssociatesAuthorship 10259231134298979De La Cruz A, Hargrave A, Magadi S, Courson JA, Landry PT, Zhang W, Lam FW, Bray MA, Smith CW, Burns AR, Rumbaut REInternational journal of molecular sciencesPlatelet and Erythrocyte Extravasation across Inflamed Corneal Venules Depend on CD18, Neutrophils, and Mast Cell Degranulation. Int J Mol Sci. 2021 Jul 08; 22(14).Int J Mol Sci2021-07-08T00:00:002021Platelet and Erythrocyte Extravasation across Inflamed Corneal Venules Depend on CD18, Neutrophils, and Mast Cell Degranulation.Authorship 1037112335011018Akowuah PK, Hargrave A, Rumbaut RE, Burns ARNutrientsDissociation between Corneal and Cardiometabolic Changes in Response to a Time-Restricted Feeding of a High Fat Diet. Nutrients. 2021 Dec 29; 14(1).Nutrients2021-12-29T00:00:002021Dissociation between Corneal and Cardiometabolic Changes in Response to a Time-Restricted Feeding of a High Fat Diet.Authorship 1182581Authorship 1040029435037655Akowuah PK, De La Cruz A, Smith CW, Rumbaut RE, Burns ARJournal of visualized experiments : JoVEAn Epithelial Abrasion Model for Studying Corneal Wound Healing. J Vis Exp. 2021 12 29; (178).J Vis Exp2021-12-29T00:00:002021An Epithelial Abrasion Model for Studying Corneal Wound Healing.Authorship 136498524358370Dasgupta SK, Le A, Haudek SB, Entman ML, Rumbaut RE, Thiagarajan PPloS oneRho associated coiled-coil kinase-1 regulates collagen-induced phosphatidylserine exposure in platelets. PLoS One. 2013; 8(12):e84649.PLoS One2013-12-16T00:00:002013Rho associated coiled-coil kinase-1 regulates collagen-induced phosphatidylserine exposure in platelets.https://www.bcm.edu/people-search/fong-lam-25023Baylor College of MedicineAuthorship 1051266635881214Bray M, Guzel MA, Lam F, Yee A, Cruz MA, Rumbaut REJournal of thrombosis and thrombolysisHigh levels of von Willebrand factor with reduced specific activities in hospitalized patients with or without COVID-19. J Thromb Thrombolysis. 2022 Aug; 54(2):211-216.J Thromb Thrombolysis2022-07-26T00:00:002022High levels of von Willebrand factor with reduced specific activities in hospitalized patients with or without COVID-19.true1ProfessorProfessorAuthorship 10562753Authorship 10577694Authorship 1060490936056797Courson JA, Lam FW, Langlois KW, Rumbaut REMicrocirculation (New York, N.Y. : 1994)Histone-stimulated platelet adhesion to mouse cremaster venules in vivo is dependent on von Willebrand factor. Microcirculation. 2022 Nov; 29(8):e12782.Microcirculation2022-09-22T00:00:002022Histone-stimulated platelet adhesion to mouse cremaster venules in vivo is dependent on von Willebrand factor.36495717Martinez-Vargas M, Cebula A, Brubaker LS, Seshadri N, Lam FW, Loor M, Rosengart TK, Yee A, Rumbaut RE, Cruz MAThrombosis researchA novel interaction between extracellular vimentin and fibrinogen in fibrin formation. Thromb Res. 2023 01; 221:97-104.Thromb Res2022-12-07T00:00:002022A novel interaction between extracellular vimentin and fibrinogen in fibrin formation.36674448Akowuah PK, Lema C, Rumbaut RE, Burns ARInternational journal of molecular sciencesA Low-Fat/Sucrose Diet Rich in Complex Carbohydrates Reverses High-Fat/Sucrose Diet-Induced Corneal Dysregulation. Int J Mol Sci. 2023 Jan 04; 24(2).Int J Mol Sci2023-01-04T00:00:002023A Low-Fat/Sucrose Diet Rich in Complex Carbohydrates Reverses High-Fat/Sucrose Diet-Induced Corneal Dysregulation.true1Adjunct ProfessorAdjunct Professortrue1Professor EmeritusProfessor Emeritustrue1Clinical ProfessorClinical ProfessorAuthorship 12411Authorship 1082742537887268Khatlani T, Pradhan S, Langlois K, Subramanyam D, Rumbaut RE, Vijayan KVCellsOpposing Roles for the a Isoform of the Catalytic Subunit of Protein Phosphatase 1 in Inside-Out and Outside-In Integrin Signaling in Murine Platelets. Cells. 2023 10 10; 12(20).Cells2023-10-10T00:00:002023Opposing Roles for the a Isoform of the Catalytic Subunit of Protein Phosphatase 1 in Inside-Out and Outside-In Integrin Signaling in Murine Platelets.Authorship 161273Authorship 1087885538271349Dasgupta SK, Gollamudi J, Rivera S, Poche RA, Rumbaut RE, Thiagarajan PPloS one?2-glycoprotein I promotes the clearance of circulating mitochondria. PLoS One. 2024; 19(1):e0293304.PLoS One2024-01-25T00:00:002024?2-glycoprotein I promotes the clearance of circulating mitochondria.Authorship 238721Authorship 20823Authorship 261462Authorship 224453Authorship 478967Authorship 37041Authorship 395203Authorship 467905Authorship 496364Authorship 709661Authorship 743976Authorship 774575Authorship 549982Authorship 845864Authorship 859491Authorship 688724