WILLIAMDECKERWILLIAM DECKER29.71073630000000-95.3966045000000036DECKER, WILLIAMProfessorprns:coAuthorOfcoauthor ofprns:endDateend dateFaculty Rankprns:fullNamefull nameprns:grantAwardedBygrant awarded byprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:physicalNeighborOfphysical neighborprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:principalInvestigatorNameprincipal investigator nameprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:startDatestart dateprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressAgreementvivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentDivisionGrantvivo:hasResearchArearesearch areasvivo:hasResearcherRoleresearch activitiesvivo:hrJobTitleHR job titleInformation Resourcevivo:linkAnchorTextlink anchor textvivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:personInPositionpositionsPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titleResearcher Rolevivo:researcherRoleOfresearcher role ofRolevivo:roleContributesTocontributes tovivo:sponsorAwardIdsponsor award idURLLinkvivo:webpagewebpagerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonAuthorship 957304Authorship 1016121Authorship 1029913Authorship 1061441Authorship 162741525376389Ni X, Jorgensen JL, Goswami M, Challagundla P, Decker WK, Kim YH, Duvic MAClinical cancer research : an official journal of the American Association for Cancer ResearchReduction of regulatory T cells by Mogamulizumab, a defucosylated anti-CC chemokine receptor 4 antibody, in patients with aggressive/refractory mycosis fungoides and S?zary syndrome. Clin Cancer Res. 2015 Jan 15; 21(2):274-85.Clin Cancer Res2014-11-05T00:00:002014Reduction of regulatory T cells by Mogamulizumab, a defucosylated anti-CC chemokine receptor 4 antibody, in patients with aggressive/refractory mycosis fungoides and S?zary syndrome.Melanoma Medical OncologyStem Cell TransplantationMD AndersonJAMES PALLISONJAMES P ALLISON8659ALLISON, JAMES PProfessorELIZABETHSHPALLELIZABETH SHPALL9025SHPALL, ELIZABETHProfessorPATRICKHWUPATRICK HWU9108HWU, PATRICKProfessorAuthorship 654411Authorship 689441Authorship 825172Authorship 97989710430654Xu X, Decker W, Sampson MJ, Craigen WJ, Colombini MThe Journal of membrane biologyMouse VDAC isoforms expressed in yeast: channel properties and their roles in mitochondrial outer membrane permeability. J Membr Biol. 1999 Jul 15; 170(2):89-102.J Membr Biol1999-07-15T00:00:001999Mouse VDAC isoforms expressed in yeast: channel properties and their roles in mitochondrial outer membrane permeability.10444329Pan Y, Decker WK, Huq AH, Craigen WJGenomicsRetrotransposition of glycerol kinase-related genes from the X chromosome to autosomes: functional and evolutionary aspects. Genomics. 1999 Aug 01; 59(3):282-90.Genomics1999-08-01T00:00:001999Retrotransposition of glycerol kinase-related genes from the X chromosome to autosomes: functional and evolutionary aspects.Authorship 2949526Authorship 2977384Authorship 2980051Authorship 30215041Authorship 30441115825818339Vinay DS, Ryan EP, Pawelec G, Talib WH, Stagg J, Elkord E, Lichtor T, Decker WK, Whelan RL, Kumara HMCS, Signori E, Honoki K, Georgakilas AG, Amin A, Helferich WG, Boosani CS, Guha G, Ciriolo MR, Chen S, Mohammed SI, Azmi AS, Keith WN, Bilsland A, Bhakta D, Halicka D, Fujii H, Aquilano K, Ashraf SS, Nowsheen S, Yang X, Choi BK, Kwon BSSeminars in cancer biologyImmune evasion in cancer: Mechanistic basis and therapeutic strategies. Semin Cancer Biol. 2015 Dec; 35 Suppl:S185-S198.Semin Cancer Biol2015-03-25T00:00:002015Immune evasion in cancer: Mechanistic basis and therapeutic strategies.26106142Goodson WH, Lowe L, Carpenter DO, Gilbertson M, Manaf Ali A, Lopez de Cerain Salsamendi A, Lasfar A, Carnero A, Azqueta A, Amedei A, Charles AK, Collins AR, Ward A, Salzberg AC, Colacci A, Olsen AK, Berg A, Barclay BJ, Zhou BP, Blanco-Aparicio C, Baglole CJ, Dong C, Mondello C, Hsu CW, Naus CC, Yedjou C, Curran CS, Laird DW, Koch DC, Carlin DJ, Felsher DW, Roy D, Brown DG, Ratovitski E, Ryan EP, Corsini E, Rojas E, Moon EY, Laconi E, Marongiu F, Al-Mulla F, Chiaradonna F, Darroudi F, Martin FL, Van Schooten FJ, Goldberg GS, Wagemaker G, Nangami GN, Calaf GM, Williams G, Wolf GT, Koppen G, Brunborg G, Lyerly HK, Krishnan H, Ab Hamid H, Yasaei H, Sone H, Kondoh H, Salem HK, Hsu HY, Park HH, Koturbash I, Miousse IR, Scovassi AI, Klaunig JE, Vondr?cek J, Raju J, Roman J, Wise JP, Whitfield JR, Woodrick J, Christopher JA, Ochieng J, Martinez-Leal JF, Weisz J, Kravchenko J, Sun J, Prudhomme KR, Narayanan KB, Cohen-Solal KA, Moorwood K, Gonzalez L, Soucek L, Jian L, D'Abronzo LS, Lin LT, Li L, Gulliver L, McCawley LJ, Memeo L, Vermeulen L, Leyns L, Zhang L, Valverde M, Khatami M, Romano MF, Chapellier M, Williams MA, Wade M, Manjili MH, Lleonart ME, Xia M, Gonzalez MJ, Karamouzis MV, Kirsch-Volders M, Vaccari M, Kuemmerle NB, Singh N, Cruickshanks N, Kleinstreuer N, van Larebeke N, Ahmed N, Ogunkua O, Krishnakumar PK, Vadgama P, Marignani PA, Ghosh PM, Ostrosky-Wegman P, Thompson PA, Dent P, Heneberg P, Darbre P, Sing Leung P, Nangia-Makker P, Cheng QS, Robey RB, Al-Temaimi R, Roy R, Andrade-Vieira R, Sinha RK, Mehta R, Vento R, Di Fiore R, Ponce-Cusi R, Dornetshuber-Fleiss R, Nahta R, Castellino RC, Palorini R, Abd Hamid R, Langie SA, Eltom SE, Brooks SA, Ryeom S, Wise SS, Bay SN, Harris SA, Papagerakis S, Romano S, Pavanello S, Eriksson S, Forte S, Casey SC, Luanpitpong S, Lee TJ, Otsuki T, Chen T, Massfelder T, Sanderson T, Guarnieri T, Hultman T, Dormoy V, Odero-Marah V, Sabbisetti V, Maguer-Satta V, Rathmell WK, Engstr?m W, Decker WK, Bisson WH, Rojanasakul Y, Luqmani Y, Chen Z, Hu ZCarcinogenesisAssessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead. Carcinogenesis. 2015 Jun; 36 Suppl 1:S254-96.Carcinogenesis2015-06-01T00:00:002015Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead.26325028Liang D, Halpert MM, Konduri V, Decker WKInternational reviews of immunologyStepping Out of the Cytosol: AIMp1/p43 Potentiates the Link Between Innate and Adaptive Immunity. Int Rev Immunol. 2015; 34(5):367-81.Int Rev Immunol2015-09-01T00:00:002015Stepping Out of the Cytosol: AIMp1/p43 Potentiates the Link Between Innate and Adaptive Immunity.26366482Decker WKInternational reviews of immunologyIn This Issue: Cellular Stress and the Interface of Innate and Adaptive Immunity, and Other Topics. Int Rev Immunol. 2015; 34(5):365-6.Int Rev Immunol2015-01-01T00:00:002015In This Issue: Cellular Stress and the Interface of Innate and Adaptive Immunity, and Other Topics.26590477Block KI, Gyllenhaal C, Lowe L, Amedei A, Amin ARMR, Amin A, Aquilano K, Arbiser J, Arreola A, Arzumanyan A, Ashraf SS, Azmi AS, Benencia F, Bhakta D, Bilsland A, Bishayee A, Blain SW, Block PB, Boosani CS, Carey TE, Carnero A, Carotenuto M, Casey SC, Chakrabarti M, Chaturvedi R, Chen GZ, Chen H, Chen S, Chen YC, Choi BK, Ciriolo MR, Coley HM, Collins AR, Connell M, Crawford S, Curran CS, Dabrosin C, Damia G, Dasgupta S, DeBerardinis RJ, Decker WK, Dhawan P, Diehl AME, Dong JT, Dou QP, Drew JE, Elkord E, El-Rayes B, Feitelson MA, Felsher DW, Ferguson LR, Fimognari C, Firestone GL, Frezza C, Fujii H, Fuster MM, Generali D, Georgakilas AG, Gieseler F, Gilbertson M, Green MF, Grue B, Guha G, Halicka D, Helferich WG, Heneberg P, Hentosh P, Hirschey MD, Hofseth LJ, Holcombe RF, Honoki K, Hsu HY, Huang GS, Jensen LD, Jiang WG, Jones LW, Karpowicz PA, Keith WN, Kerkar SP, Khan GN, Khatami M, Ko YH, Kucuk O, Kulathinal RJ, Kumar NB, Kwon BS, Le A, Lea MA, Lee HY, Lichtor T, Lin LT, Locasale JW, Lokeshwar BL, Longo VD, Lyssiotis CA, MacKenzie KL, Malhotra M, Marino M, Martinez-Chantar ML, Matheu A, Maxwell C, McDonnell E, Meeker AK, Mehrmohamadi M, Mehta K, Michelotti GA, Mohammad RM, Mohammed SI, Morre DJ, Muralidhar V, Muqbil I, Murphy MP, Nagaraju GP, Nahta R, Niccolai E, Nowsheen S, Panis C, Pantano F, Parslow VR, Pawelec G, Pedersen PL, Poore B, Poudyal D, Prakash S, Prince M, Raffaghello L, Rathmell JC, Rathmell WK, Ray SK, Reichrath J, Rezazadeh S, Ribatti D, Ricciardiello L, Robey RB, Rodier F, Rupasinghe HPV, Russo GL, Ryan EP, Samadi AK, Sanchez-Garcia I, Sanders AJ, Santini D, Sarkar M, Sasada T, Saxena NK, Shackelford RE, Shantha Kumara HMC, Sharma D, Shin DM, Sidransky D, Siegelin MD, Signori E, Singh N, Sivanand S, Sliva D, Smythe C, Spagnuolo C, Stafforini DM, Stagg J, Subbarayan PR, Sundin T, Talib WH, Thompson SK, Tran PT, Ungefroren H, Vander Heiden MG, Venkateswaran V, Vinay DS, Vlachostergios PJ, Wang Z, Wellen KE, Whelan RL, Yang ES, Yang H, Yang X, Yaswen P, Yedjou C, Yin X, Zhu J, Zollo MSeminars in cancer biologyDesigning a broad-spectrum integrative approach for cancer prevention and treatment. Semin Cancer Biol. 2015 Dec; 35 Suppl:S276-S304.Semin Cancer Biol2015-12-01T00:00:002015Designing a broad-spectrum integrative approach for cancer prevention and treatment.9804816Sampson MJ, Ross L, Decker WK, Craigen WJThe Journal of biological chemistryA novel isoform of the mitochondrial outer membrane protein VDAC3 via alternative splicing of a 3-base exon. Functional characteristics and subcellular localization. J Biol Chem. 1998 Nov 13; 273(46):30482-6.J Biol Chem1998-11-13T00:00:001998A novel isoform of the mitochondrial outer membrane protein VDAC3 via alternative splicing of a 3-base exon. Functional characteristics and subcellular localization.10525161Wu S, Sampson MJ, Decker WK, Craigen WJBiochimica et biophysica actaEach mammalian mitochondrial outer membrane porin protein is dispensable: effects on cellular respiration. Biochim Biophys Acta. 1999 Oct 13; 1452(1):68-78.Biochim Biophys Acta1999-10-13T00:00:001999Each mammalian mitochondrial outer membrane porin protein is dispensable: effects on cellular respiration.10501981Decker WK, Bowles KR, Schatte EC, Towbin JA, Craigen WJMammalian genome : official journal of the International Mammalian Genome SocietyRevised fine mapping of the human voltage-dependent anion channel loci by radiation hybrid analysis. Mamm Genome. 1999 Oct; 10(10):1041-2.Mamm Genome1999-10-01T00:00:001999Revised fine mapping of the human voltage-dependent anion channel loci by radiation hybrid analysis.10833333Decker WK, Craigen WJMolecular genetics and metabolismThe tissue-specific, alternatively spliced single ATG exon of the type 3 voltage-dependent anion channel gene does not create a truncated protein isoform in vivo. Mol Genet Metab. 2000 May; 70(1):69-74.Mol Genet Metab2000-05-01T00:00:002000The tissue-specific, alternatively spliced single ATG exon of the type 3 voltage-dependent anion channel gene does not create a truncated protein isoform in vivo.26979751Halpert MM, Konduri V, Liang D, Chen Y, Wing JB, Paust S, Levitt JM, Decker WKStem cells and developmentDendritic Cell-Secreted Cytotoxic T-Lymphocyte-Associated Protein-4 Regulates the T-cell Response by Downmodulating Bystander Surface B7. Stem Cells Dev. 2016 05 15; 25(10):774-87.Stem Cells Dev2016-05-02T00:00:002016Dendritic Cell-Secreted Cytotoxic T-Lymphocyte-Associated Protein-4 Regulates the T-cell Response by Downmodulating Bystander Surface B7.74Professor37Dean10Assistant Professor21Chair14Associate ProfessorAuthorship 321230818166249Zhang Y, Qiu J, Zhou Y, Farhangfar F, Hester J, Lin AY, Decker WKVaccinePlasmid-based vaccination with candidate anthrax vaccine antigens induces durable type 1 and type 2 T-helper immune responses. Vaccine. 2008 Jan 30; 26(5):614-22.Vaccine2007-12-18T00:00:002007Plasmid-based vaccination with candidate anthrax vaccine antigens induces durable type 1 and type 2 T-helper immune responses.18481385Decker WK, Li S, Xing D, Robinson SN, Yang H, Steiner D, Komanduri KV, Bollard CM, Shpall EJJournal of immunotherapy (Hagerstown, Md. : 1997)Deficient T(H)-1 responses from TNF-alpha-matured and alpha-CD40-matured dendritic cells. J Immunother. 2008 Feb-Mar; 31(2):157-65.J Immunother2008-02-01T00:00:002008Deficient T(H)-1 responses from TNF-alpha-matured and alpha-CD40-matured dendritic cells.53Graduate Student19443656Hanley PJ, Cruz CR, Savoldo B, Leen AM, Stanojevic M, Khalil M, Decker W, Molldrem JJ, Liu H, Gee AP, Rooney CM, Heslop HE, Dotti G, Brenner MK, Shpall EJ, Bollard CMBloodFunctionally active virus-specific T cells that target CMV, adenovirus, and EBV can be expanded from naive T-cell populations in cord blood and will target a range of viral epitopes. Blood. 2009 Aug 27; 114(9):1958-67.Blood2009-05-14T00:00:002009Functionally active virus-specific T cells that target CMV, adenovirus, and EBV can be expanded from naive T-cell populations in cord blood and will target a range of viral epitopes.19544439Steiner D, Gelovani J, Savoldo B, Robinson SN, Decker WK, Brouard N, Najjar A, Xing D, Yang H, Li S, Marini F, Zweidler-McKay PA, Bollard CM, Shpall EJ, Dotti G, Simmons PJStem cells (Dayton, Ohio)Noninvasive bioluminescent imaging demonstrates long-term multilineage engraftment of ex vivo-expanded CD34-selected umbilical cord blood cells. Stem Cells. 2009 Aug; 27(8):1932-40.Stem Cells2009-08-01T00:00:002009Noninvasive bioluminescent imaging demonstrates long-term multilineage engraftment of ex vivo-expanded CD34-selected umbilical cord blood cells.21862380Decker WK, Safdar ACytokine & growth factor reviewsCytokine adjuvants for vaccine therapy of neoplastic and infectious disease. Cytokine Growth Factor Rev. 2011 Aug; 22(4):177-87.Cytokine Growth Factor Rev2011-08-20T00:00:002011Cytokine adjuvants for vaccine therapy of neoplastic and infectious disease.22303459Shahi P, Park D, Pond AC, Seethammagari M, Chiou SH, Cho K, Carstens JL, Decker WK, McCrea PD, Ittmann MM, Rosen JM, Spencer DMPloS oneActivation of Wnt signaling by chemically induced dimerization of LRP5 disrupts cellular homeostasis. PLoS One. 2012; 7(1):e30814.PLoS One2012-01-27T00:00:002012Activation of Wnt signaling by chemically induced dimerization of LRP5 disrupts cellular homeostasis.23239987Couch RB, Decker WK, Utama B, Atmar RL, Ni?o D, Feng JQ, Halpert MM, Air GMPloS oneEvaluations for in vitro correlates of immunogenicity of inactivated influenza a H5, H7 and H9 vaccines in humans. PLoS One. 2012; 7(12):e50830.PLoS One2012-12-11T00:00:002012Evaluations for in vitro correlates of immunogenicity of inactivated influenza a H5, H7 and H9 vaccines in humans.16443510Decker WK, Xing D, Shpall EJBiology of blood and marrow transplantation : journal of the American Society for Blood and Marrow TransplantationDendritic cell immunotherapy for the treatment of neoplastic disease. Biol Blood Marrow Transplant. 2006 Feb; 12(2):113-25.Biol Blood Marrow Transplant2006-02-01T00:00:002006Dendritic cell immunotherapy for the treatment of neoplastic disease.23460750Konduri V, Decker WK, Halpert MM, Gilbert B, Safdar AThe Journal of infectious diseasesModeling dendritic cell vaccination for influenza prophylaxis: potential applications for niche populations. J Infect Dis. 2013 Jun 01; 207(11):1764-72.J Infect Dis2013-03-04T00:00:002013Modeling dendritic cell vaccination for influenza prophylaxis: potential applications for niche populations.16698688Parmar S, Robinson SN, Komanduri K, St John L, Decker W, Xing D, Yang H, McMannis J, Champlin R, de Lima M, Molldrem J, Rieber A, Bonyhadi M, Berenson R, Shpall EJCytotherapyEx vivo expanded umbilical cord blood T cells maintain naive phenotype and TCR diversity. Cytotherapy. 2006; 8(2):149-57.Cytotherapy2006-01-01T00:00:002006Ex vivo expanded umbilical cord blood T cells maintain naive phenotype and TCR diversity.19171878Decker WK, Xing D, Li S, Robinson SN, Yang H, Steiner D, Komanduri KV, Shpall EJBloodTh-1 polarization is regulated by dendritic-cell comparison of MHC class I and class II antigens. Blood. 2009 Apr 30; 113(18):4213-23.Blood2009-01-26T00:00:002009Th-1 polarization is regulated by dendritic-cell comparison of MHC class I and class II antigens.19185049Safdar A, Decker WK, Li S, Xing D, Robinson SN, Yang H, Steiner D, Rodriguez G, Shpall EJ, Bollard CVaccineDe novo T-lymphocyte responses against baculovirus-derived recombinant influenzavirus hemagglutinin generated by a naive umbilical cord blood model of dendritic cell vaccination. Vaccine. 2009 Mar 04; 27(10):1479-84.Vaccine2009-02-06T00:00:002009De novo T-lymphocyte responses against baculovirus-derived recombinant influenzavirus hemagglutinin generated by a naive umbilical cord blood model of dendritic cell vaccination.Authorship 6535191127757308Konduri V, Li D, Halpert MM, Liang D, Liang Z, Chen Y, Fisher WE, Paust S, Levitt JM, Yao QC, Decker WKOncoimmunologyChemo-immunotherapy mediates durable cure of orthotopic KrasG12D/p53-/- pancreatic ductal adenocarcinoma. Oncoimmunology. 2016; 5(9):e1213933.Oncoimmunology2016-07-22T00:00:002016Chemo-immunotherapy mediates durable cure of orthotopic KrasG12D/p53-/- pancreatic ductal adenocarcinoma.19838220Yang H, Robinson SN, Lu J, Decker WK, Xing D, Steiner D, Parmar S, Shah N, Champlin RE, Munsell M, Leen A, Bollard C, Simmons PJ, Shpall EJBone marrow transplantationCD3(+) and/or CD14(+) depletion from cord blood mononuclear cells before ex vivo expansion culture improves total nucleated cell and CD34(+) cell yields. Bone Marrow Transplant. 2010 Jun; 45(6):1000-7.Bone Marrow Transplant2009-10-19T00:00:002009CD3(+) and/or CD14(+) depletion from cord blood mononuclear cells before ex vivo expansion culture improves total nucleated cell and CD34(+) cell yields.20624046Decker WK, Safdar AExpert review of vaccinesDendritic cell vaccines for the immunocompromised patient: prevention of influenza virus infection. Expert Rev Vaccines. 2010 Jul; 9(7):721-30.Expert Rev Vaccines2010-07-01T00:00:002010Dendritic cell vaccines for the immunocompromised patient: prevention of influenza virus infection.20664358Xing D, Ramsay AG, Gribben JG, Decker WK, Burks JK, Munsell M, Li S, Robinson SN, Yang H, Steiner D, Shah N, McMannis JD, Champlin RE, Hosing C, Zweidler-McKay PA, Shpall EJ, Bollard CMJournal of immunotherapy (Hagerstown, Md. : 1997)Cord blood natural killer cells exhibit impaired lytic immunological synapse formation that is reversed with IL-2 exvivo expansion. J Immunother. 2010 Sep; 33(7):684-96.J Immunother2010-09-01T00:00:002010Cord blood natural killer cells exhibit impaired lytic immunological synapse formation that is reversed with IL-2 exvivo expansion.21912635Perin EC, Tian M, Marini FC, Silva GV, Zheng Y, Baimbridge F, Quan X, Fernandes MR, Gahremanpour A, Young D, Paolillo V, Mukhopadhyay U, Borne AT, Uthamanthil R, Brammer D, Jackson J, Decker WK, Najjar AM, Thomas MW, Volgin A, Rabinovich B, Soghomonyan S, Jeong HJ, Rios JM, Steiner D, Robinson S, Mawlawi O, Pan T, Stafford J, Kundra V, Li C, Alauddin MM, Willerson JT, Shpall E, Gelovani JGPloS oneImaging long-term fate of intramyocardially implanted mesenchymal stem cells in a porcine myocardial infarction model. PLoS One. 2011; 6(9):e22949.PLoS One2011-09-01T00:00:002011Imaging long-term fate of intramyocardially implanted mesenchymal stem cells in a porcine myocardial infarction model.22306295Robinson SN, Simmons PJ, Thomas MW, Brouard N, Javni JA, Trilok S, Shim JS, Yang H, Steiner D, Decker WK, Xing D, Shultz LD, Savoldo B, Dotti G, Bollard CM, Miller L, Champlin RE, Shpall EJ, Zweidler-McKay PAExperimental hematologyEx?vivo fucosylation improves human cord blood engraftment in NOD-SCID IL-2R?(null) mice. Exp Hematol. 2012 Jun; 40(6):445-56.Exp Hematol2012-02-02T00:00:002012Ex?vivo fucosylation improves human cord blood engraftment in NOD-SCID IL-2R?(null) mice.23284688Decker WK, Shah N, Xing D, Lapushin R, Li S, Robinson SN, Yang H, Parmar S, Halpert MM, Keating MJ, Gribben JG, Molldrem JJ, Shpall EJ, Wierda WGPloS oneGeneration of functional CLL-specific cord blood CTL using CD40-ligated CLL APC. PLoS One. 2012; 7(12):e51390.PLoS One2012-12-19T00:00:002012Generation of functional CLL-specific cord blood CTL using CD40-ligated CLL APC.28371798Tian L, Goldstein A, Wang H, Ching Lo H, Sun Kim I, Welte T, Sheng K, Dobrolecki LE, Zhang X, Putluri N, Phung TL, Mani SA, Stossi F, Sreekumar A, Mancini MA, Decker WK, Zong C, Lewis MT, Zhang XHNatureMutual regulation of tumour vessel normalization and immunostimulatory reprogramming. Nature. 2017 04 13; 544(7649):250-254.Nature2017-04-03T00:00:002017Mutual regulation of tumour vessel normalization and immunostimulatory reprogramming.Authorship 869089168884278Huq AH, Lovell RS, Sampson MJ, Decker WK, Dinulos MB, Disteche CM, Craigen WJGenomicsIsolation, mapping, and functional expression of the mouse X chromosome glycerol kinase gene. Genomics. 1996 Sep 15; 36(3):530-4.Genomics1996-09-15T00:00:001996Isolation, mapping, and functional expression of the mouse X chromosome glycerol kinase gene.28674032Konduri V, Halpert MM, Liang D, Levitt JM, Cruz-Chan JV, Zhan B, Bottazzi ME, Hotez PJ, Jones KM, Decker WKInfection and immunityGenetic Adjuvantation of a Cell-Based Therapeutic Vaccine for Amelioration of Chagasic Cardiomyopathy. Infect Immun. 2017 09; 85(9).Infect Immun2017-08-18T00:00:002017Genetic Adjuvantation of a Cell-Based Therapeutic Vaccine for Amelioration of Chagasic Cardiomyopathy.Authorship 8753231016019131Decker WK, Qiu J, Farhangfar F, Hester JH, Altieri DC, Lin AYCancer lettersA retrogen plasmid-based vaccine generates high titer antibody responses against the autologous cancer antigen survivin and demonstrates anti-tumor efficacy. Cancer Lett. 2006 Jun 08; 237(1):45-55.Cancer Lett2005-07-12T00:00:002005A retrogen plasmid-based vaccine generates high titer antibody responses against the autologous cancer antigen survivin and demonstrates anti-tumor efficacy.16400333Robinson SN, Ng J, Niu T, Yang H, McMannis JD, Karandish S, Kaur I, Fu P, Del Angel M, Messinger R, Flagge F, de Lima M, Decker W, Xing D, Champlin R, Shpall EJBone marrow transplantationSuperior ex vivo cord blood expansion following co-culture with bone marrow-derived mesenchymal stem cells. Bone Marrow Transplant. 2006 Feb; 37(4):359-66.Bone Marrow Transplant2006-02-01T00:00:002006Superior ex vivo cord blood expansion following co-culture with bone marrow-derived mesenchymal stem cells.16435011Yang H, Eaves C, de Lima M, Lee MS, Champlin RE, McMannis JD, Robinson SN, Niu T, Decker WK, Xing D, Ng J, Li S, Yao X, Eaves AC, Jones R, Andersson BS, Shpall EJBone marrow transplantationA novel triple purge strategy for eliminating chronic myelogenous leukemia (CML) cells from autografts. Bone Marrow Transplant. 2006 Mar; 37(6):575-82.Bone Marrow Transplant2006-03-01T00:00:002006A novel triple purge strategy for eliminating chronic myelogenous leukemia (CML) cells from autografts.16480795Decker WK, Xing D, Li S, Robinson SN, Yang H, Yao X, Segall H, McMannis JD, Komanduri KV, Champlin RE, Shpall EJVaccineDouble loading of dendritic cell MHC class I and MHC class II with an AML antigen repertoire enhances correlates of T-cell immunity in vitro via amplification of T-cell help. Vaccine. 2006 Apr 12; 24(16):3203-16.Vaccine2006-01-23T00:00:002006Double loading of dendritic cell MHC class I and MHC class II with an AML antigen repertoire enhances correlates of T-cell immunity in vitro via amplification of T-cell help.16698683Xing D, Decker WK, Li S, Robinson SN, Yang H, Segal H, O'Connor S, Yao X, Komanduri KV, McMannis JD, Jones RB, de Lima M, Champlin RE, Shpall EJCytotherapyAML-loaded DC generate Th1-type cellular immune responses in vitro. Cytotherapy. 2006; 8(2):95-104.Cytotherapy2006-01-01T00:00:002006AML-loaded DC generate Th1-type cellular immune responses in vitro.18382128Decker WK, Shpall EJHuman vaccinesProgress in dendritic cell immunotherapy: elucidating the enigma of Th-1 polarization. Hum Vaccin. 2008 Mar-Apr; 4(2):162-4.Hum Vaccin2007-09-26T00:00:002007Progress in dendritic cell immunotherapy: elucidating the enigma of Th-1 polarization.18480841Ni X, Richmond HM, Liao XM, Decker WK, Shiue LH, Shpall EJ, Duvic MThe Journal of investigative dermatologyInduction of T-cell responses against cutaneous T-cell lymphomas ex vivo by autologous dendritic cells transfected with amplified tumor mRNA. J Invest Dermatol. 2008 Nov; 128(11):2631-2639.J Invest Dermatol2008-05-15T00:00:002008Induction of T-cell responses against cutaneous T-cell lymphomas ex vivo by autologous dendritic cells transfected with amplified tumor mRNA.19656718Decker WK, Safdar ACytokine & growth factor reviewsBioimmunoadjuvants for the treatment of neoplastic and infectious disease: Coley's legacy revisited. Cytokine Growth Factor Rev. 2009 Aug; 20(4):271-81.Cytokine Growth Factor Rev2009-08-04T00:00:002009Bioimmunoadjuvants for the treatment of neoplastic and infectious disease: Coley's legacy revisited.21646477Yang H, Robinson SN, Nieto Y, Jones RJ, Gocke CD, Lu J, Giralt SA, Jones RB, Decker WK, Xing D, Steiner D, Champlin RE, McMannis JD, Ng J, Thomas MW, Shah N, Andersson BS, Parmar S, Shpall EJCancer researchEx vivo graft purging and expansion of autologous blood progenitor cell products from patients with multiple myeloma. Cancer Res. 2011 Jul 15; 71(14):5040-9.Cancer Res2011-06-06T00:00:002011Ex vivo graft purging and expansion of autologous blood progenitor cell products from patients with multiple myeloma.Authorship 87943117Authorship 885251128824608Decker WK, da Silva RF, Sanabria MH, Angelo LS, Guimar?es F, Burt BM, Kheradmand F, Paust SFrontiers in immunologyCancer Immunotherapy: Historical Perspective of a Clinical Revolution and Emerging Preclinical Animal Models. Front Immunol. 2017; 8:829.Front Immunol2017-08-02T00:00:002017Cancer Immunotherapy: Historical Perspective of a Clinical Revolution and Emerging Preclinical Animal Models.29379495Liang D, Tian L, You R, Halpert MM, Konduri V, Baig YC, Paust S, Kim D, Kim S, Jia F, Huang S, Zhang X, Kheradmand F, Corry DB, Gilbert BE, Levitt JM, Decker WKFrontiers in immunologyAIMp1 Potentiates TH1 Polarization and Is Critical for Effective Antitumor and Antiviral Immunity. Front Immunol. 2017; 8:1801.Front Immunol2018-01-15T00:00:002018AIMp1 Potentiates TH1 Polarization and Is Critical for Effective Antitumor and Antiviral Immunity.true1Associate ProfessorAssociate ProfessorD003713Anatomy36310800.616455Dendritic CellsD018417Anatomy1492500.872155Th1 CellsD018414Anatomy56915760.568005CD8-Positive T-LymphocytesD019496Chemicals & Drugs2336960.647037Cancer VaccinesAuthorship 9384541530670791Konduri V, Halpert MM, Baig YC, Coronado R, Rodgers JR, Levitt JM, Cerroni B, Piscoya S, Wilson N, DiBernardi L, Omarbekov Z, Seelhoff L, Ravi V, Douglass L, Decker WKCancer gene therapyDendritic cell vaccination plus low-dose doxorubicin for the treatment of spontaneous canine hemangiosarcoma. Cancer Gene Ther. 2019 09; 26(9-10):282-291.Cancer Gene Ther2019-01-23T00:00:002019Dendritic cell vaccination plus low-dose doxorubicin for the treatment of spontaneous canine hemangiosarcoma.2022-02-28NIHDECKER, WILLIAM KARL2017-03-13Regulation of Innate Dendritic Cell CTLA-4R01AI127387Principal InvestigatorD007156Physiology1993740.828112Immunologic MemoryImmunologyDepartment of NeurologyDepartment of PediatricsDepartment of Molecular & Human GeneticsDepartment of Pathology & ImmunologyPediatrics-Tropical MedicineImmunologyMolecular & Human GeneticsNeurologyPathologyPediatrics-Hem/Onc Cell & Gene TheBaylor College of MedicineCAROLINAGUTIERREZCAROLINA GUTIERREZ29.71073630000000-95.39660450000000100GUTIERREZ, CAROLINAProfessorJENNIFERSPINLERJENNIFER SPINLER29.71073630000000-95.396604500000001036SPINLER, JENNIFERAssistant ProfessorAuthorship 1102251PETERHOTEZPETER HOTEZ0.000000000000000.000000000000001900HOTEZ, PETERProfessor2.470460.0048313389research areas4.78150.02229475coauthor of36.65558.5291860similar to1157selected publicationsWILLIAMCRAIGENWILLIAM CRAIGEN29.70508570000000-95.401808700000002934CRAIGEN, WILLIAMProfessorCLIONAROONEYCLIONA ROONEY0.000000000000000.000000000000003578ROONEY, CLIONAProfessorMINCHENMIN CHEN29.71073630000000-95.39660450000000366CHEN, MINAssociate ProfessorROYSILLITOEROY SILLITOE29.71073630000000-95.396604500000004100SILLITOE, ROYProfessorELIMIZRAHIELI MIZRAHI29.71073630000000-95.396604500000002944MIZRAHI, ELIProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessorCancer & Cell BiologyAuthorship 112972Authorship 1117812Authorship 1124239VANAJAKONDURIVANAJA KONDURI0.000000000000000.000000000000006100KONDURI, VANAJAAssistant ProfessorAuthorship 9874661032298026Halpert MM, Konduri V, Liang D, Vazquez-Perez J, Hofferek CJ, Weldon SA, Baig Y, Vedula I, Levitt JM, Decker WKFASEB journal : official publication of the Federation of American Societies for Experimental BiologyMHC class I and II peptide homology regulates the cellular immune response. FASEB J. 2020 06; 34(6):8082-8101.FASEB J2020-04-16T00:00:002020MHC class I and II peptide homology regulates the cellular immune response.Authorship 988285932345916Verrico CD, Wesson S, Konduri V, Hofferek CJ, Vazquez-Perez J, Blair E, Dunner K, Salimpour P, Decker WK, Halpert MMPainA randomized, double-blind, placebo-controlled study of daily cannabidiol for the treatment of canine osteoarthritis pain. Pain. 2020 09 01; 161(9):2191-2202.Pain2020-09-01T00:00:002020A randomized, double-blind, placebo-controlled study of daily cannabidiol for the treatment of canine osteoarthritis pain.JonathanVazquez-PerezJonathan Vazquez-Perez15881Vazquez-Perez, JonathanGraduate StudentAuthorship 1165651true1Graduate StudentGraduate Studenthttp://peterhotez.orgpeterhotez.orghttps://www.bcm.edu/people/view/peter-hotez-m-d-ph-d/b1846a47-ffed-11e2-be68-080027880ca6Biohttps://www.bcm.edu/education/schools/national-school-of-tropical-medicineNational School of Tropical MedicineAuthorship 1184904Authorship 1129515Authorship 1007533633384695Oyewole-Said D, Konduri V, Vazquez-Perez J, Weldon SA, Levitt JM, Decker WKFrontiers in immunologyBeyond T-Cells: Functional Characterization of CTLA-4 Expression in Immune and Non-Immune Cell Types. Front Immunol. 2020; 11:608024.Front Immunol2020-12-15T00:00:002020Beyond T-Cells: Functional Characterization of CTLA-4 Expression in Immune and Non-Immune Cell Types.Authorship 1134893Authorship 12031517Authorship 1011730733597948Konduri V, Oyewole-Said D, Vazquez-Perez J, Weldon SA, Halpert MM, Levitt JM, Decker WKFrontiers in immunologyCD8+CD161+ T-Cells: Cytotoxic Memory Cells With High Therapeutic Potential. Front Immunol. 2020; 11:613204.Front Immunol2021-02-01T00:00:002021CD8+CD161+ T-Cells: Cytotoxic Memory Cells With High Therapeutic Potential.2025-04-30NIHDECKER, WILLIAM KARL2021-05-01Innate DC Govern TH Polarization through the Novel Regulator AIMp1R01AI153326Principal InvestigatorAuthorship 10177602033952672Konduri V, Joseph SK, Byrd TT, Nawas Z, Vazquez-Perez J, Hofferek CJ, Halpert MM, Liu D, Liang Z, Baig Y, Salsman VS, Oyewole-Said D, Tsimelzon A, Burns BA, Chen C, Levitt JM, Yao Q, Ahmed NM, Hegde M, Decker WKScience translational medicineA subset of cytotoxic effector memory T cells enhances CAR T cell efficacy in a model of pancreatic ductal adenocarcinoma. Sci Transl Med. 2021 05 05; 13(592).Sci Transl Med2021-05-05T00:00:002021A subset of cytotoxic effector memory T cells enhances CAR T cell efficacy in a model of pancreatic ductal adenocarcinoma.true1Assistant ProfessorAssistant ProfessorAuthorship 10236312634244308Li F, Deng L, Jackson KR, Talukder AH, Katailiha AS, Bradley SD, Zou Q, Chen C, Huo C, Chiu Y, Stair M, Feng W, Bagaev A, Kotlov N, Svekolkin V, Ataullakhanov R, Miheecheva N, Frenkel F, Wang Y, Zhang M, Hawke D, Han L, Zhou S, Zhang Y, Wang Z, Decker WK, Sonnemann HM, Roszik J, Forget MA, Davies MA, Bernatchez C, Yee C, Bassett R, Hwu P, Du X, Lizee GJournal for immunotherapy of cancerNeoantigen vaccination induces clinical and immunologic responses in non-small cell lung cancer patients harboring EGFR mutations. J Immunother Cancer. 2021 07; 9(7).J Immunother Cancer2021-07-01T00:00:002021Neoantigen vaccination induces clinical and immunologic responses in non-small cell lung cancer patients harboring EGFR mutations.Authorship 137378724204673Shah N, Martin-Antonio B, Yang H, Ku S, Lee DA, Cooper LJ, Decker WK, Li S, Robinson SN, Sekine T, Parmar S, Gribben J, Wang M, Rezvani K, Yvon E, Najjar A, Burks J, Kaur I, Champlin RE, Bollard CM, Shpall EJPloS oneAntigen presenting cell-mediated expansion of human umbilical cord blood yields log-scale expansion of natural killer cells with anti-myeloma activity. PLoS One. 2013; 8(10):e76781.PLoS One2013-10-18T00:00:002013Antigen presenting cell-mediated expansion of human umbilical cord blood yields log-scale expansion of natural killer cells with anti-myeloma activity.true1Graduate StudentGraduate StudentColbyHofferekColby James Hofferek17584Hofferek, ColbyGraduate Studenttrue1ProfessorProfessortrue1ProfessorProfessortrue1Assistant ProfessorAssistant ProfessorAuthorship 1054783836002187Ahmed KM, Veeramachaneni R, Deng D, Putluri N, Putluri V, Cardenas MF, Wheeler DA, Decker WK, Frederick AI, Kazi S, Sikora AG, Sandulache VC, Frederick MJJournal for immunotherapy of cancerGlutathione peroxidase 2 is a metabolic driver of the tumor immune microenvironment and immune checkpoint inhibitor response. J Immunother Cancer. 2022 08; 10(8).J Immunother Cancer2022-08-01T00:00:002022Glutathione peroxidase 2 is a metabolic driver of the tumor immune microenvironment and immune checkpoint inhibitor response.true1ProfessorProfessorAuthorship 200275Authorship 10870881238239430Jones KM, Zhan B, Ernste KJ, Villar MJ, Bisht N, Nguyen D, Chang LY, Poveda C, Robinson GJ, Trivedi AJ, Hofferek CJ, Decker WK, Konduri VFrontiers in parasitologyImmunomodulatory proteins from hookworms reduce cardiac inflammation and modulate regulatory responses in a mouse model of chronic Trypanosoma cruzi infection. Front Parasitol. 2023; 2.Front Parasitol2023-10-12T00:00:002023Immunomodulatory proteins from hookworms reduce cardiac inflammation and modulate regulatory responses in a mouse model of chronic Trypanosoma cruzi infection.Authorship 10884601238312352Sobhani N, Tardiel-Cyril DR, Chai D, Generali D, Li JR, Vazquez-Perez J, Lim JM, Morris R, Bullock ZN, Davtyan A, Cheng C, Decker WK, Li YBJC reportsArtificial intelligence-powered discovery of small molecules inhibiting CTLA-4 in cancer. BJC Rep. 2024; 2.BJC Rep2024-01-23T00:00:002024Artificial intelligence-powered discovery of small molecules inhibiting CTLA-4 in cancer.true1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessorAuthorship 232012Authorship 277384Authorship 291101Authorship 300221Authorship 336202Authorship 515461Authorship 373081Authorship 549621Authorship 380808Authorship 389332Authorship 609421Authorship 4620510Authorship 561974Authorship 8251413Authorship 909189Authorship 752837