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Connection

MICHAEL LEWIS to Breast Neoplasms

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This is a "connection" page, showing publications MICHAEL LEWIS has written about Breast Neoplasms.
MICHAEL LEWIS
Connection Strength
4.375
Breast Neoplasms
  1. The Power and Promise of Patient-Derived Xenografts of Human Breast Cancer. Cold Spring Harb Perspect Med. 2024 04 01; 14(4).
    View in: PubMed
    Score: 0.388
  2. Surgical Procedure for Implantation of Human Tumor Tissue into the Epithelium-Free Mammary Fat Pad of Immunocompromised Mice to Generate Patient-Derived Xenografts (PDX). Methods Mol Biol. 2022; 2471:195-207.
    View in: PubMed
    Score: 0.332
  3. New paradigms for the Hedgehog signaling network in mammary gland development and breast Cancer. Biochim Biophys Acta Rev Cancer. 2017 Aug; 1868(1):315-332.
    View in: PubMed
    Score: 0.242
  4. The Terminal End Bud: the Little Engine that Could. J Mammary Gland Biol Neoplasia. 2017 06; 22(2):93-108.
    View in: PubMed
    Score: 0.236
  5. Identifying and targeting tumor-initiating cells in the treatment of breast cancer. Endocr Relat Cancer. 2015 Jun; 22(3):R135-55.
    View in: PubMed
    Score: 0.208
  6. STAT3 signaling is activated preferentially in tumor-initiating cells in claudin-low models of human breast cancer. Stem Cells. 2014 Oct; 32(10):2571-82.
    View in: PubMed
    Score: 0.201
  7. A renewable tissue resource of phenotypically stable, biologically and ethnically diverse, patient-derived human breast cancer xenograft models. Cancer Res. 2013 Aug 01; 73(15):4885-97.
    View in: PubMed
    Score: 0.183
  8. Selective small molecule Stat3 inhibitor reduces breast cancer tumor-initiating cells and improves recurrence free survival in a human-xenograft model. PLoS One. 2012; 7(8):e30207.
    View in: PubMed
    Score: 0.173
  9. Hedgehog signaling in the normal and neoplastic mammary gland. Curr Drug Targets. 2010 Sep; 11(9):1103-11.
    View in: PubMed
    Score: 0.151
  10. The more things change... the more things change: developmental plasticity of tumor-initiating mammary epithelial cells. Breast Cancer Res. 2010; 12(1):101.
    View in: PubMed
    Score: 0.144
  11. Methods in mammary gland biology and breast cancer research: an update. J Mammary Gland Biol Neoplasia. 2009 Dec; 14(4):365.
    View in: PubMed
    Score: 0.144
  12. Faith, heresy and the cancer stem cell hypothesis. Future Oncol. 2008 Oct; 4(5):585-9.
    View in: PubMed
    Score: 0.132
  13. Cyclopamine inhibition of human breast cancer cell growth independent of Smoothened (Smo). Breast Cancer Res Treat. 2009 Jun; 115(3):505-21.
    View in: PubMed
    Score: 0.130
  14. Embryogenesis and oncogenesis: Dr Jekyll and Mr Hyde. J Mammary Gland Biol Neoplasia. 2004 Apr; 9(2):105-7.
    View in: PubMed
    Score: 0.097
  15. Transcriptional Reprogramming Differentiates Active from Inactive ESR1 Fusions in Endocrine Therapy-Refractory Metastatic Breast Cancer. Cancer Res. 2021 12 15; 81(24):6259-6272.
    View in: PubMed
    Score: 0.082
  16. VEGF-C mediates tumor growth and metastasis through promoting EMT-epithelial breast cancer cell crosstalk. Oncogene. 2021 02; 40(5):964-979.
    View in: PubMed
    Score: 0.077
  17. Orthotopic Transplantation of Breast Tumors as Preclinical Models for Breast Cancer. J Vis Exp. 2020 05 18; (159).
    View in: PubMed
    Score: 0.074
  18. Two Sides of the Same Coin: The Role of Developmental pathways and pluripotency factors in normal mammary stem cells and breast cancer metastasis. J Mammary Gland Biol Neoplasia. 2020 06; 25(2):85-102.
    View in: PubMed
    Score: 0.074
  19. Homeobox genes in mammary gland development and neoplasia. Breast Cancer Res. 2000; 2(3):158-69.
    View in: PubMed
    Score: 0.073
  20. The Altered Transcriptome and DNA Methylation Profiles of Docetaxel Resistance in Breast Cancer PDX Models. Mol Cancer Res. 2019 10; 17(10):2063-2076.
    View in: PubMed
    Score: 0.070
  21. Circulating tumor cell investigation in breast cancer patient-derived xenograft models by automated immunofluorescence staining, image acquisition, and single cell retrieval and analysis. BMC Cancer. 2019 Mar 12; 19(1):220.
    View in: PubMed
    Score: 0.068
  22. C/EBPd links IL-6 and HIF-1 signaling to promote breast cancer stem cell-associated phenotypes. Oncogene. 2019 05; 38(20):3765-3780.
    View in: PubMed
    Score: 0.066
  23. Differentiation-state plasticity is a targetable resistance mechanism in basal-like breast cancer. Nat Commun. 2018 09 19; 9(1):3815.
    View in: PubMed
    Score: 0.066
  24. Pharmacological targeting of MYC-regulated IRE1/XBP1 pathway suppresses MYC-driven breast cancer. J Clin Invest. 2018 04 02; 128(4):1283-1299.
    View in: PubMed
    Score: 0.064
  25. EMT cells increase breast cancer metastasis via paracrine GLI activation in neighbouring tumour cells. Nat Commun. 2017 06 12; 8:15773.
    View in: PubMed
    Score: 0.060
  26. Patient-derived xenograft (PDX) models in basic and translational breast cancer research. Cancer Metastasis Rev. 2016 12; 35(4):547-573.
    View in: PubMed
    Score: 0.058
  27. Wild-Type N-Ras, Overexpressed in Basal-like Breast Cancer, Promotes Tumor Formation by Inducing IL-8 Secretion via JAK2 Activation. Cell Rep. 2015 Jul 21; 12(3):511-24.
    View in: PubMed
    Score: 0.053
  28. Patient-derived xenograft models of breast cancer and their predictive power. Breast Cancer Res. 2015 Feb 10; 17:17.
    View in: PubMed
    Score: 0.051
  29. Circulating and disseminated tumor cells from breast cancer patient-derived xenograft-bearing mice as a novel model to study metastasis. Breast Cancer Res. 2015 Jan 09; 17:3.
    View in: PubMed
    Score: 0.051
  30. Drug-repositioning screening identified piperlongumine as a direct STAT3 inhibitor with potent activity against breast cancer. Oncogene. 2015 Mar 12; 34(11):1341-53.
    View in: PubMed
    Score: 0.048
  31. Paracrine Wnt signaling both promotes and inhibits human breast tumor growth. Proc Natl Acad Sci U S A. 2013 Apr 23; 110(17):6991-6.
    View in: PubMed
    Score: 0.045
  32. Preclinical and clinical studies of gamma secretase inhibitors with docetaxel on human breast tumors. Clin Cancer Res. 2013 Mar 15; 19(6):1512-24.
    View in: PubMed
    Score: 0.045
  33. Estrogen promotes ER-negative tumor growth and angiogenesis through mobilization of bone marrow-derived monocytes. Cancer Res. 2012 Jun 01; 72(11):2705-13.
    View in: PubMed
    Score: 0.042
  34. Integrative physical oncology. Wiley Interdiscip Rev Syst Biol Med. 2012 Jan-Feb; 4(1):1-14.
    View in: PubMed
    Score: 0.040
  35. High IGF-IR activity in triple-negative breast cancer cell lines and tumorgrafts correlates with sensitivity to anti-IGF-IR therapy. Clin Cancer Res. 2011 Apr 15; 17(8):2314-27.
    View in: PubMed
    Score: 0.039
  36. Mesenchymal stem cells promote mammosphere formation and decrease E-cadherin in normal and malignant breast cells. PLoS One. 2010 Aug 16; 5(8):e12180.
    View in: PubMed
    Score: 0.038
  37. DNA repair signature is associated with anthracycline response in triple negative breast cancer patients. Breast Cancer Res Treat. 2010 Aug; 123(1):189-96.
    View in: PubMed
    Score: 0.037
  38. Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features. Proc Natl Acad Sci U S A. 2009 Aug 18; 106(33):13820-5.
    View in: PubMed
    Score: 0.035
  39. Androgen receptor overexpression induces tamoxifen resistance in human breast cancer cells. Breast Cancer Res Treat. 2010 May; 121(1):1-11.
    View in: PubMed
    Score: 0.035
  40. Decreased TGFbeta signaling and increased COX2 expression in high risk women with increased mammographic breast density. Breast Cancer Res Treat. 2010 Jan; 119(2):305-14.
    View in: PubMed
    Score: 0.034
  41. Evidence that an early pregnancy causes a persistent decrease in the number of functional mammary epithelial stem cells--implications for pregnancy-induced protection against breast cancer. Stem Cells. 2008 Dec; 26(12):3205-9.
    View in: PubMed
    Score: 0.033
  42. Intrinsic resistance of tumorigenic breast cancer cells to chemotherapy. J Natl Cancer Inst. 2008 May 07; 100(9):672-9.
    View in: PubMed
    Score: 0.032
  43. Patterns of resistance and incomplete response to docetaxel by gene expression profiling in breast cancer patients. J Clin Oncol. 2005 Feb 20; 23(6):1169-77.
    View in: PubMed
    Score: 0.026
  44. Next stop, the twilight zone: hedgehog network regulation of mammary gland development. J Mammary Gland Biol Neoplasia. 2004 Apr; 9(2):165-81.
    View in: PubMed
    Score: 0.024
  45. MAPK4 promotes triple negative breast cancer growth and reduces tumor sensitivity to PI3K blockade. Nat Commun. 2022 01 11; 13(1):245.
    View in: PubMed
    Score: 0.021
  46. Regulated expression patterns of IRX-2, an Iroquois-class homeobox gene, in the human breast. Cell Tissue Res. 1999 Jun; 296(3):549-54.
    View in: PubMed
    Score: 0.017
  47. Oncogenic mTOR signalling recruits myeloid-derived suppressor cells to promote tumour initiation. Nat Cell Biol. 2016 06; 18(6):632-44.
    View in: PubMed
    Score: 0.014
  48. Identification and Characterization of Separase Inhibitors (Sepins) for Cancer Therapy. J Biomol Screen. 2014 Jul; 19(6):878-89.
    View in: PubMed
    Score: 0.012
  49. Dicer-mediated upregulation of BCRP confers tamoxifen resistance in human breast cancer cells. Clin Cancer Res. 2011 Oct 15; 17(20):6510-21.
    View in: PubMed
    Score: 0.010
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.