Connection

ARUN SREEKUMAR to Humans

This is a "connection" page, showing publications ARUN SREEKUMAR has written about Humans.
Connection Strength

0.504
  1. DHODH links mitochondrial bioenergetics, one-carbon metabolism, and DNA repair to sustain aggressive prostate adenocarcinoma. Cell Commun Signal. 2026 Jan 29; 24(1).
    View in: PubMed
    Score: 0.026
  2. Integrative spatial omics reveals distinct tumor-promoting multicellular niches and immunosuppressive mechanisms in Black American and White American patients with TNBC. Nat Commun. 2025 Jul 17; 16(1):6584.
    View in: PubMed
    Score: 0.025
  3. Crafting effective health appeals: Language and source credibility in amplifying tobacco control messages on social media. Health Mark Q. 2025 Jul-Sep; 42(3):257-281.
    View in: PubMed
    Score: 0.024
  4. Uridine Diphosphate Glucuronosyl Transferase 2B28 (UGT2B28) Promotes Tumor Progression and Is Elevated in African American Prostate Cancer Patients. Cells. 2022 07 29; 11(15).
    View in: PubMed
    Score: 0.020
  5. UDP-glucose 6-dehydrogenase regulates hyaluronic acid production and promotes breast cancer progression. Oncogene. 2020 04; 39(15):3089-3101.
    View in: PubMed
    Score: 0.016
  6. ERR1 and PGC1a associated mitochondrial alterations correlate with pan-cancer disparity in African Americans. J Clin Invest. 2019 03 28; 129(6):2351-2356.
    View in: PubMed
    Score: 0.016
  7. A Bottom-Up Approach to Understanding Low-Income Patients: Implications for Health-Related Policy. J Law Med Ethics. 2018 Sep; 46(3):658-664.
    View in: PubMed
    Score: 0.015
  8. Inhibition of the hexosamine biosynthetic pathway promotes castration-resistant prostate cancer. Nat Commun. 2016 05 19; 7:11612.
    View in: PubMed
    Score: 0.013
  9. Genomic Aberrations Drive Clonal Evolution of Neuroendocrine Tumors. Trends Endocrinol Metab. 2016 05; 27(5):242-244.
    View in: PubMed
    Score: 0.013
  10. Metabolomic profiling of hormone-dependent cancers: a bird's eye view. Trends Endocrinol Metab. 2015 Sep; 26(9):477-85.
    View in: PubMed
    Score: 0.012
  11. Pathway-centric integrative analysis identifies RRM2 as a prognostic marker in breast cancer associated with poor survival and tamoxifen resistance. Neoplasia. 2014 May; 16(5):390-402.
    View in: PubMed
    Score: 0.011
  12. Metabolomic profiling reveals potential markers and bioprocesses altered in bladder cancer progression. Cancer Res. 2011 Dec 15; 71(24):7376-86.
    View in: PubMed
    Score: 0.010
  13. Metabolomic profiling reveals a role for androgen in activating amino acid metabolism and methylation in prostate cancer cells. PLoS One. 2011; 6(7):e21417.
    View in: PubMed
    Score: 0.009
  14. Metabolites of purine nucleoside phosphorylase (NP) in serum have the potential to delineate pancreatic adenocarcinoma. PLoS One. 2011 Mar 23; 6(3):e17177.
    View in: PubMed
    Score: 0.009
  15. Re: Florian Jentzmik, Carsten Stephan, Kurt Miller, et al. Sarcosine in urine after digital rectal examination fails as a marker in prostate cancer detection and identification of aggressive tumours. Eur Urol 2010;58:12-8. Eur Urol. 2010 Sep; 58(3):e29-30; author reply e31-2.
    View in: PubMed
    Score: 0.009
  16. Quantitative proteomic profiling of prostate cancer reveals a role for miR-128 in prostate cancer. Mol Cell Proteomics. 2010 Feb; 9(2):298-312.
    View in: PubMed
    Score: 0.008
  17. Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression. Nature. 2009 Feb 12; 457(7231):910-4.
    View in: PubMed
    Score: 0.008
  18. Humoral response profiling reveals pathways to prostate cancer progression. Mol Cell Proteomics. 2008 Mar; 7(3):600-11.
    View in: PubMed
    Score: 0.007
  19. Cigarette smoke induces FASN-dependent fatty acid metabolic rewiring to drive bladder cancer progression. Cancer Lett. 2026 Aug 10; 653:218562.
    View in: PubMed
    Score: 0.007
  20. The hexosamine biosynthetic pathway alters the cytoskeleton to modulate cell proliferation and migration in aggressive prostate cancer. Cell Commun Signal. 2026 Mar 28; 24(1).
    View in: PubMed
    Score: 0.007
  21. PARP inhibitor response is enhanced in prostate cancer when XRCC1 expression is reduced. NAR Cancer. 2025 Jun; 7(2):zcaf015.
    View in: PubMed
    Score: 0.006
  22. Mitochondrial reprogramming by activating OXPHOS via glutamine metabolism in African American patients with bladder cancer. JCI Insight. 2024 09 10; 9(17).
    View in: PubMed
    Score: 0.006
  23. MYC Induces Oncogenic Stress through RNA Decay and Ribonucleotide Catabolism in Breast Cancer. Cancer Discov. 2024 Sep 04; 14(9):1699-1716.
    View in: PubMed
    Score: 0.006
  24. Humoral immune response to alpha-methylacyl-CoA racemase and prostate cancer. J Natl Cancer Inst. 2004 Jun 02; 96(11):834-43.
    View in: PubMed
    Score: 0.006
  25. The IL6/JAK/STAT3 signaling axis is a therapeutic vulnerability in SMARCB1-deficient bladder cancer. Nat Commun. 2024 02 14; 15(1):1373.
    View in: PubMed
    Score: 0.006
  26. Proteogenomic Approaches for the Identification of NF1/Neurofibromin-depleted Estrogen Receptor-positive Breast Cancers for Targeted Treatment. Cancer Res Commun. 2023 07; 3(7):1366-1377.
    View in: PubMed
    Score: 0.005
  27. Spatial mapping of the DNA adducts in cancer. DNA Repair (Amst). 2023 08; 128:103529.
    View in: PubMed
    Score: 0.005
  28. Histone H2A Lys130 acetylation epigenetically regulates androgen production in prostate cancer. Nat Commun. 2023 06 09; 14(1):3357.
    View in: PubMed
    Score: 0.005
  29. Conjugated bile acids are nutritionally re-programmable antihypertensive metabolites. J Hypertens. 2023 06 01; 41(6):979-994.
    View in: PubMed
    Score: 0.005
  30. Using protein microarrays to study cancer. Biotechniques. 2002 Dec; Suppl:46-53.
    View in: PubMed
    Score: 0.005
  31. Protein microarrays: a powerful tool to study cancer. Curr Opin Mol Ther. 2002 Dec; 4(6):587-93.
    View in: PubMed
    Score: 0.005
  32. Profiling of cancer cells using protein microarrays: discovery of novel radiation-regulated proteins. Cancer Res. 2001 Oct 15; 61(20):7585-93.
    View in: PubMed
    Score: 0.005
  33. Pancreatic Differentiation of Stem Cells Reveals Pathogenesis of a Syndrome of Ketosis-Prone Diabetes. Diabetes. 2021 10; 70(10):2419-2429.
    View in: PubMed
    Score: 0.005
  34. Neuropeptide Y nerve paracrine regulation of prostate cancer oncogenesis and therapy resistance. Prostate. 2021 01; 81(1):58-71.
    View in: PubMed
    Score: 0.004
  35. Dnmt3a loss and Idh2 neomorphic mutations mutually potentiate malignant hematopoiesis. Blood. 2020 03 12; 135(11):845-856.
    View in: PubMed
    Score: 0.004
  36. DNA methylation patterns in bladder tumors of African American patients point to distinct alterations in xenobiotic metabolism. Carcinogenesis. 2019 11 25; 40(11):1332-1340.
    View in: PubMed
    Score: 0.004
  37. Epigenetic loss of AOX1 expression via EZH2 leads to metabolic deregulations and promotes bladder cancer progression. Oncogene. 2020 10; 39(40):6265-6285.
    View in: PubMed
    Score: 0.004
  38. Oncogenic lncRNA downregulates cancer cell antigen presentation and intrinsic tumor suppression. Nat Immunol. 2019 07; 20(7):835-851.
    View in: PubMed
    Score: 0.004
  39. Multi-omics Integration Analysis Robustly Predicts High-Grade Patient Survival and Identifies CPT1B Effect on Fatty Acid Metabolism in Bladder Cancer. Clin Cancer Res. 2019 06 15; 25(12):3689-3701.
    View in: PubMed
    Score: 0.004
  40. Molecular Profiling Reveals Unique Immune and Metabolic Features of Melanoma Brain Metastases. Cancer Discov. 2019 05; 9(5):628-645.
    View in: PubMed
    Score: 0.004
  41. Serum Metabolic Profiling Identified a Distinct Metabolic Signature in Bladder Cancer Smokers: A Key Metabolic Enzyme Associated with Patient Survival. Cancer Epidemiol Biomarkers Prev. 2019 04; 28(4):770-781.
    View in: PubMed
    Score: 0.004
  42. Large-scale profiling of serum metabolites in African American and European American patients with bladder cancer reveals metabolic pathways associated with patient survival. Cancer. 2019 03 15; 125(6):921-932.
    View in: PubMed
    Score: 0.004
  43. Mitochondrial pyruvate import is a metabolic vulnerability in androgen receptor-driven prostate cancer. Nat Metab. 2019 01; 1(1):70-85.
    View in: PubMed
    Score: 0.004
  44. Analysis of cerebrospinal fluid metabolites in patients with primary or metastatic central nervous system tumors. Acta Neuropathol Commun. 2018 08 31; 6(1):85.
    View in: PubMed
    Score: 0.004
  45. Expression of Long Noncoding RNA YIYA Promotes Glycolysis in Breast Cancer. Cancer Res. 2018 08 15; 78(16):4524-4532.
    View in: PubMed
    Score: 0.004
  46. Cisplatin generates oxidative stress which is accompanied by rapid shifts in central carbon metabolism. Sci Rep. 2018 03 09; 8(1):4306.
    View in: PubMed
    Score: 0.004
  47. GLUT12 promotes prostate cancer cell growth and is regulated by androgens and CaMKK2 signaling. Endocr Relat Cancer. 2018 04; 25(4):453-469.
    View in: PubMed
    Score: 0.004
  48. Potential role of Plasmodium falciparum exported protein 1 in the chloroquine mode of action. Int J Parasitol Drugs Drug Resist. 2018 04; 8(1):31-35.
    View in: PubMed
    Score: 0.004
  49. ADHFE1 is a breast cancer oncogene and induces metabolic reprogramming. J Clin Invest. 2018 01 02; 128(1):323-340.
    View in: PubMed
    Score: 0.004
  50. Tobacco-Specific Carcinogens Induce Hypermethylation, DNA Adducts, and DNA Damage in Bladder Cancer. Cancer Prev Res (Phila). 2017 Oct; 10(10):588-597.
    View in: PubMed
    Score: 0.004
  51. Distinct Lipidomic Landscapes Associated with Clinical Stages of Urothelial Cancer of the Bladder. Eur Urol Focus. 2018 12; 4(6):907-915.
    View in: PubMed
    Score: 0.003
  52. Mutual regulation of tumour vessel normalization and immunostimulatory reprogramming. Nature. 2017 04 13; 544(7649):250-254.
    View in: PubMed
    Score: 0.003
  53. Promoter Methylation Modulates Indoleamine 2,3-Dioxygenase 1 Induction by Activated T Cells in Human Breast Cancers. Cancer Immunol Res. 2017 04; 5(4):330-344.
    View in: PubMed
    Score: 0.003
  54. Circadian Homeostasis of Liver Metabolism Suppresses Hepatocarcinogenesis. Cancer Cell. 2016 Dec 12; 30(6):909-924.
    View in: PubMed
    Score: 0.003
  55. MNX1 Is Oncogenically Upregulated in African-American Prostate Cancer. Cancer Res. 2016 11 01; 76(21):6290-6298.
    View in: PubMed
    Score: 0.003
  56. High throughput microscopy identifies bisphenol AP, a bisphenol A analog, as a novel AR down-regulator. Oncotarget. 2016 Mar 29; 7(13):16962-74.
    View in: PubMed
    Score: 0.003
  57. Fatty Acid Oxidation-Driven Src Links Mitochondrial Energy Reprogramming and Oncogenic Properties in Triple-Negative Breast Cancer. Cell Rep. 2016 Mar 08; 14(9):2154-2165.
    View in: PubMed
    Score: 0.003
  58. Integrative Pathway Analysis of Metabolic Signature in Bladder Cancer: A Linkage to The Cancer Genome Atlas Project and Prediction of Survival. J Urol. 2016 06; 195(6):1911-9.
    View in: PubMed
    Score: 0.003
  59. An Immune-Inflammation Gene Expression Signature in Prostate Tumors of Smokers. Cancer Res. 2016 Mar 01; 76(5):1055-1065.
    View in: PubMed
    Score: 0.003
  60. EMT-induced metabolite signature identifies poor clinical outcome. Oncotarget. 2015 Dec 15; 6(40):42651-60.
    View in: PubMed
    Score: 0.003
  61. Differential regulation of metabolic pathways by androgen receptor (AR) and its constitutively active splice variant, AR-V7, in prostate cancer cells. Oncotarget. 2015 Oct 13; 6(31):31997-2012.
    View in: PubMed
    Score: 0.003
  62. Platelet-Synthesized Testosterone in Men with Prostate Cancer Induces Androgen Receptor Signaling. Neoplasia. 2015 Jun; 17(6):490-6.
    View in: PubMed
    Score: 0.003
  63. CAPER is vital for energy and redox homeostasis by integrating glucose-induced mitochondrial functions via ERR-a-Gabpa and stress-induced adaptive responses via NF-?B-cMYC. PLoS Genet. 2015 Apr; 11(4):e1005116.
    View in: PubMed
    Score: 0.003
  64. Proteomic profiling of na?ve multiple myeloma patient plasma cells identifies pathways associated with favourable response to bortezomib-based treatment regimens. Br J Haematol. 2015 Jul; 170(1):66-79.
    View in: PubMed
    Score: 0.003
  65. Coactivator SRC-2-dependent metabolic reprogramming mediates prostate cancer survival and metastasis. J Clin Invest. 2015 Mar 02; 125(3):1174-88.
    View in: PubMed
    Score: 0.003
  66. Metabolomic profiling identifies biochemical pathways associated with castration-resistant prostate cancer. J Proteome Res. 2014 Feb 07; 13(2):1088-100.
    View in: PubMed
    Score: 0.003
  67. MYC-driven accumulation of 2-hydroxyglutarate is associated with breast cancer prognosis. J Clin Invest. 2014 Jan; 124(1):398-412.
    View in: PubMed
    Score: 0.003
  68. Application of 13C isotope labeling using liquid chromatography mass spectrometry (LC-MS) to determining phosphate-containing metabolic incorporation. J Mass Spectrom. 2013 Dec; 48(12):1270-5.
    View in: PubMed
    Score: 0.003
  69. Acceleration of the glycolytic flux by steroid receptor coactivator-2 is essential for endometrial decidualization. PLoS Genet. 2013 Oct; 9(10):e1003900.
    View in: PubMed
    Score: 0.003
  70. The role of sarcosine metabolism in prostate cancer progression. Neoplasia. 2013 May; 15(5):491-501.
    View in: PubMed
    Score: 0.003
  71. A dual role for receptor-interacting protein kinase 2 (RIP2) kinase activity in nucleotide-binding oligomerization domain 2 (NOD2)-dependent autophagy. J Biol Chem. 2012 Jul 20; 287(30):25565-76.
    View in: PubMed
    Score: 0.002
  72. Pathway-directed weighted testing procedures for the integrative analysis of gene expression and metabolomic data. Genomics. 2012 May; 99(5):265-74.
    View in: PubMed
    Score: 0.002
  73. The nucleotide synthesis enzyme CAD inhibits NOD2 antibacterial function in human intestinal epithelial cells. Gastroenterology. 2012 Jun; 142(7):1483-92.e6.
    View in: PubMed
    Score: 0.002
  74. Novel role of androgens in mitochondrial fission and apoptosis. Mol Cancer Res. 2011 Aug; 9(8):1067-77.
    View in: PubMed
    Score: 0.002
  75. Genome-wide DNA methylation maps in follicular lymphoma cells determined by methylation-enriched bisulfite sequencing. PLoS One. 2010 Sep 29; 5(9).
    View in: PubMed
    Score: 0.002
  76. "Topological significance" analysis of gene expression and proteomic profiles from prostate cancer cells reveals key mechanisms of androgen response. PLoS One. 2010 Jun 03; 5(6):e10936.
    View in: PubMed
    Score: 0.002
  77. Proteomic interrogation of androgen action in prostate cancer cells reveals roles of aminoacyl tRNA synthetases. PLoS One. 2009 Sep 18; 4(9):e7075.
    View in: PubMed
    Score: 0.002
  78. Combined epigenetic therapy with the histone methyltransferase EZH2 inhibitor 3-deazaneplanocin A and the histone deacetylase inhibitor panobinostat against human AML cells. Blood. 2009 Sep 24; 114(13):2733-43.
    View in: PubMed
    Score: 0.002
  79. Golgi protein GOLM1 is a tissue and urine biomarker of prostate cancer. Neoplasia. 2008 Nov; 10(11):1285-94.
    View in: PubMed
    Score: 0.002
  80. Copper & biological health. Indian J Med Res. 2008 Oct; 128(4):448-61.
    View in: PubMed
    Score: 0.002
  81. A role for the MLL fusion partner ENL in transcriptional elongation and chromatin modification. Blood. 2007 Dec 15; 110(13):4445-54.
    View in: PubMed
    Score: 0.002
  82. Differential phosphoprotein mapping in cancer cells using protein microarrays produced from 2-D liquid fractionation. Anal Chem. 2006 Feb 01; 78(3):702-10.
    View in: PubMed
    Score: 0.002
  83. Trisomy 12-associated, t(11;14)-negative mature B-cell leukemia with gene expression profile resembling mantle cell lymphoma. Leuk Lymphoma. 2006 Jan; 47(1):121-7.
    View in: PubMed
    Score: 0.002
  84. Autoantibody signatures in prostate cancer. N Engl J Med. 2005 Sep 22; 353(12):1224-35.
    View in: PubMed
    Score: 0.002
  85. Serum antibodies to huntingtin interacting protein-1: a new blood test for prostate cancer. Cancer Res. 2005 May 15; 65(10):4126-33.
    View in: PubMed
    Score: 0.002
  86. Radiosensitization by pan ErbB inhibitor CI-1033 in vitro and in vivo. Clin Cancer Res. 2004 Jan 15; 10(2):691-700.
    View in: PubMed
    Score: 0.001
  87. Development of a sensitive microarray immunoassay and comparison with standard enzyme-linked immunoassay for cytokine analysis. Shock. 2004 Jan; 21(1):26-30.
    View in: PubMed
    Score: 0.001
  88. Protein microarrays using liquid phase fractionation of cell lysates. Proteomics. 2003 Jul; 3(7):1228-35.
    View in: PubMed
    Score: 0.001
  89. Pentoxifylline induced signalling events during capacitation of hamster spermatozoa: significance of protein tyrosine phosphorylation. Cell Mol Biol (Noisy-le-grand). 2003 May; 49(3):371-80.
    View in: PubMed
    Score: 0.001
  90. High and selective expression of yeast cytosine deaminase under a carcinoembryonic antigen promoter-enhancer. Cancer Res. 2002 Apr 15; 62(8):2337-42.
    View in: PubMed
    Score: 0.001
  91. Molecular cross-talk between the TRAIL and interferon signaling pathways. J Biol Chem. 2002 Jan 04; 277(1):575-85.
    View in: PubMed
    Score: 0.001
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.