SOPHIA TSAI to Humans
This is a "connection" page, showing publications SOPHIA TSAI has written about Humans.
Connection Strength
0.344
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Nuclear receptors regulate alternative lengthening of telomeres through a novel noncanonical FANCD2 pathway. Sci Adv. 2019 10; 5(10):eaax6366.
Score: 0.018
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The Role of COUP-TFII in Striated Muscle Development and Disease. Curr Top Dev Biol. 2017; 125:375-403.
Score: 0.015
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Preface. Curr Top Dev Biol. 2017; 125:xv-xvi.
Score: 0.015
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COUP-TFII inhibits TGF-?-induced growth barrier to promote prostate tumorigenesis. Nature. 2013 Jan 10; 493(7431):236-40.
Score: 0.011
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COUP-TFII is a major regulator of cell cycle and Notch signaling pathways. Mol Endocrinol. 2012 Aug; 26(8):1268-77.
Score: 0.011
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Nuclear receptor COUP-TFII controls pancreatic islet tumor angiogenesis by regulating vascular endothelial growth factor/vascular endothelial growth factor receptor-2 signaling. Cancer Res. 2010 Nov 01; 70(21):8812-21.
Score: 0.010
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Artery and vein formation: a tug of war between different forces. EMBO Rep. 2007 Oct; 8(10):920-4.
Score: 0.008
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The regulation of COUP-TFII gene expression by Ets-1 is enhanced by the steroid receptor co-activators. Mech Ageing Dev. 2004 Oct-Nov; 125(10-11):719-32.
Score: 0.006
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Cdc25B as a steroid receptor coactivator. Vitam Horm. 2004; 68:231-56.
Score: 0.006
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Overexpression of Cdc25B, an androgen receptor coactivator, in prostate cancer. Oncogene. 2003 Feb 06; 22(5):734-9.
Score: 0.006
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Induction of chicken ovalbumin upstream promoter-transcription factor I (COUP-TFI ) gene expression is mediated by ETS factor binding sites. Eur J Biochem. 2002 Jan; 269(1):317-25.
Score: 0.005
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Targeted gene regulation and gene ablation. Trends Endocrinol Metab. 2001 Oct; 12(8):348-53.
Score: 0.005
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COUP-TF orphan nuclear receptors in development and differentiation. Cell Mol Life Sci. 2000 Sep; 57(10):1388-98.
Score: 0.005
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Elevated COUP-TFII expression in dopaminergic neurons accelerates the progression of Parkinson's disease through mitochondrial dysfunction. PLoS Genet. 2020 06; 16(6):e1008868.
Score: 0.005
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Opposing Functions of BRD4 Isoforms in Breast Cancer. Mol Cell. 2020 06 18; 78(6):1114-1132.e10.
Score: 0.005
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Small-molecule inhibitor targeting orphan nuclear receptor COUP-TFII for prostate cancer treatment. Sci Adv. 2020 05; 6(18):eaaz8031.
Score: 0.005
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Small molecule JQ1 promotes prostate cancer invasion via BET-independent inactivation of FOXA1. J Clin Invest. 2020 04 01; 130(4):1782-1792.
Score: 0.005
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Induction of mammary gland hyperplasia in transgenic mice over-expressing human Cdc25B. Oncogene. 1999 Aug 12; 18(32):4564-76.
Score: 0.004
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Suppression of gene expression by tethering KRAB domain to promoter of ER target genes. J Steroid Biochem Mol Biol. 1999 Apr-Jun; 69(1-6):155-63.
Score: 0.004
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SRC-3 Coactivator Governs Dynamic Estrogen-Induced Chromatin Looping Interactions during Transcription. Mol Cell. 2018 05 17; 70(4):679-694.e7.
Score: 0.004
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Metabolic enzyme PFKFB4 activates transcriptional coactivator SRC-3 to drive breast cancer. Nature. 2018 04; 556(7700):249-254.
Score: 0.004
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A regulatory system for target gene expression. Front Biosci. 1998 Jan 01; 3:c1-7.
Score: 0.004
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Acetylation on histone H3 lysine 9 mediates a switch from transcription initiation to elongation. J Biol Chem. 2017 09 01; 292(35):14456-14472.
Score: 0.004
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Positive and negative regulation of gene expression in eukaryotic cells with an inducible transcriptional regulator. Gene Ther. 1997 May; 4(5):432-41.
Score: 0.004
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Chick ovalbumin upstream promoter-transcription factors (COUP-TFs): coming of age. Endocr Rev. 1997 Apr; 18(2):229-40.
Score: 0.004
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Dysregulation of miRNAs-COUP-TFII-FOXM1-CENPF axis contributes to the metastasis of prostate cancer. Nat Commun. 2016 04 25; 7:11418.
Score: 0.004
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MPC1, a key gene in cancer metabolism, is regulated by COUPTFII in human prostate cancer. Oncotarget. 2016 Mar 22; 7(12):14673-83.
Score: 0.004
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Choose your destiny: Make a cell fate decision with COUP-TFII. J Steroid Biochem Mol Biol. 2016 Mar; 157:7-12.
Score: 0.003
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Sequence and characterization of a coactivator for the steroid hormone receptor superfamily. Science. 1995 Nov 24; 270(5240):1354-7.
Score: 0.003
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Estrogen Receptor ? Modulates Apoptosis Complexes and the Inflammasome to Drive the Pathogenesis of Endometriosis. Cell. 2015 Nov 05; 163(4):960-74.
Score: 0.003
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Stimulation of human insulin receptor gene expression by retinoblastoma gene product. J Biol Chem. 1995 Sep 01; 270(35):20525-9.
Score: 0.003
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Isolation, characterization, and chromosomal localization of mouse and human COUP-TF I and II genes. Genomics. 1995 Sep 01; 29(1):240-6.
Score: 0.003
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CAPER is vital for energy and redox homeostasis by integrating glucose-induced mitochondrial functions via ERR-a-Gabpa and stress-induced adaptive responses via NF-?B-cMYC. PLoS Genet. 2015 Apr; 11(4):e1005116.
Score: 0.003
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E1a activation of insulin receptor gene expression is mediated by Sp1-binding sites. Mol Endocrinol. 1995 Feb; 9(2):178-86.
Score: 0.003
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Androgen deprivation-induced NCoA2 promotes metastatic and castration-resistant prostate cancer. J Clin Invest. 2014 Nov; 124(11):5013-26.
Score: 0.003
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The role of the orphan nuclear receptor COUP-TFII in tumorigenesis. Acta Pharmacol Sin. 2015 Jan; 36(1):32-6.
Score: 0.003
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Perturbing the cellular levels of steroid receptor coactivator-2 impairs murine endometrial function. PLoS One. 2014; 9(6):e98664.
Score: 0.003
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COUP-TFs and eye development. Biochim Biophys Acta. 2015 Feb; 1849(2):201-9.
Score: 0.003
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Multiple hormone response elements can confer glucocorticoid regulation on the human insulin receptor gene. Mol Endocrinol. 1994 May; 8(5):625-34.
Score: 0.003
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E2/Estrogen receptor/sjogren syndrome-associated autoantigen relieves coactivator activator-induced G1/S arrest to promote breast tumorigenicity. Mol Cell Biol. 2014 May; 34(9):1670-81.
Score: 0.003
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NR2F1 mutations cause optic atrophy with intellectual disability. Am J Hum Genet. 2014 Feb 06; 94(2):303-9.
Score: 0.003
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Suppression of COUP-TFII by proinflammatory cytokines contributes to the pathogenesis of endometriosis. J Clin Endocrinol Metab. 2014 Mar; 99(3):E427-37.
Score: 0.003
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COUP-TFII regulates human endometrial stromal genes involved in inflammation. Mol Endocrinol. 2013 Dec; 27(12):2041-54.
Score: 0.003
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Regulatory potential of COUP-TFs in development: stem/progenitor cells. Semin Cell Dev Biol. 2013 Dec; 24(10-12):687-93.
Score: 0.003
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Proteomic analysis of coregulators bound to ERa on DNA and nucleosomes reveals coregulator dynamics. Mol Cell. 2013 Jul 25; 51(2):185-99.
Score: 0.003
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COUP-TFII, a prognostic marker and therapeutic target for prostate cancer. Asian J Androl. 2013 May; 15(3):360-1.
Score: 0.003
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Analysis of the mechanism of steroid hormone receptor-dependent gene activation in cell-free systems. Endocr Rev. 1992 Aug; 13(3):525-35.
Score: 0.003
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ERK3 signals through SRC-3 coactivator to promote human lung cancer cell invasion. J Clin Invest. 2012 May; 122(5):1869-80.
Score: 0.003
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Identification of cis- and trans-acting factors regulating the expression of the human insulin receptor gene. J Biol Chem. 1992 Mar 05; 267(7):4638-45.
Score: 0.003
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Recombinant human glucocorticoid receptor induces transcription of hormone response genes in vitro. J Biol Chem. 1990 Oct 05; 265(28):17055-61.
Score: 0.002
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Generation of ES cells for conditional expression of nuclear receptors and coregulators in vivo. Mol Endocrinol. 2010 Jun; 24(6):1297-304.
Score: 0.002
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Research resource: expression profiling reveals unexpected targets and functions of the human steroid receptor RNA activator (SRA) gene. Mol Endocrinol. 2010 May; 24(5):1090-105.
Score: 0.002
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SRC-3Delta4 mediates the interaction of EGFR with FAK to promote cell migration. Mol Cell. 2010 Feb 12; 37(3):321-32.
Score: 0.002
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Biochemical control of CARM1 enzymatic activity by phosphorylation. J Biol Chem. 2009 Dec 25; 284(52):36167-36174.
Score: 0.002
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Mig-6 modulates uterine steroid hormone responsiveness and exhibits altered expression in endometrial disease. Proc Natl Acad Sci U S A. 2009 May 26; 106(21):8677-82.
Score: 0.002
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A germline mutation (A339V) in thyroid transcription factor-1 (TITF-1/NKX2.1) in patients with multinodular goiter and papillary thyroid carcinoma. J Natl Cancer Inst. 2009 Feb 04; 101(3):162-75.
Score: 0.002
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Chicken Ovalbumin Upstream Promoter-Transcription Factor II (COUP-TFII) regulates growth and patterning of the postnatal mouse cerebellum. Dev Biol. 2009 Feb 15; 326(2):378-91.
Score: 0.002
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Dual roles for coactivator activator and its counterbalancing isoform coactivator modulator in human kidney cell tumorigenesis. Cancer Res. 2008 Oct 01; 68(19):7887-96.
Score: 0.002
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Essential phosphatases and a phospho-degron are critical for regulation of SRC-3/AIB1 coactivator function and turnover. Mol Cell. 2008 Sep 26; 31(6):835-49.
Score: 0.002
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Identification of COUP-TFII orphan nuclear receptor as a retinoic acid-activated receptor. PLoS Biol. 2008 Sep 16; 6(9):e227.
Score: 0.002
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Steroid receptor coactivator-3/AIB1 promotes cell migration and invasiveness through focal adhesion turnover and matrix metalloproteinase expression. Cancer Res. 2008 Jul 01; 68(13):5460-8.
Score: 0.002
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Atypical protein kinase C regulates dual pathways for degradation of the oncogenic coactivator SRC-3/AIB1. Mol Cell. 2008 Feb 29; 29(4):465-76.
Score: 0.002
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In vivo analysis of progesterone receptor action in the uterus during embryo implantation. Semin Cell Dev Biol. 2008 Apr; 19(2):178-86.
Score: 0.002
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Bmp2 is critical for the murine uterine decidual response. Mol Cell Biol. 2007 Aug; 27(15):5468-78.
Score: 0.002
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Deregulated CDC25A expression promotes mammary tumorigenesis with genomic instability. Cancer Res. 2007 Feb 01; 67(3):984-91.
Score: 0.002
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Specific amino acid residues in the basic helix-loop-helix domain of SRC-3 are essential for its nuclear localization and proteasome-dependent turnover. Mol Cell Biol. 2007 Feb; 27(4):1296-308.
Score: 0.002
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Steroid receptor coactivator-3 and activator protein-1 coordinately regulate the transcription of components of the insulin-like growth factor/AKT signaling pathway. Cancer Res. 2006 Nov 15; 66(22):11039-46.
Score: 0.002
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Oncogenic steroid receptor coactivator-3 is a key regulator of the white adipogenic program. Proc Natl Acad Sci U S A. 2006 Nov 21; 103(47):17868-73.
Score: 0.002
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SRC-3/AIB1: transcriptional coactivator in oncogenesis. Acta Pharmacol Sin. 2006 Apr; 27(4):387-94.
Score: 0.002
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The SRC-3/AIB1 coactivator is degraded in a ubiquitin- and ATP-independent manner by the REGgamma proteasome. Cell. 2006 Jan 27; 124(2):381-92.
Score: 0.002
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Peptidyl-prolyl isomerase 1 (Pin1) serves as a coactivator of steroid receptor by regulating the activity of phosphorylated steroid receptor coactivator 3 (SRC-3/AIB1). Mol Cell Biol. 2005 Nov; 25(21):9687-99.
Score: 0.002
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SRC-3 is required for prostate cancer cell proliferation and survival. Cancer Res. 2005 Sep 01; 65(17):7976-83.
Score: 0.002
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Selective phosphorylations of the SRC-3/AIB1 coactivator integrate genomic reponses to multiple cellular signaling pathways. Mol Cell. 2004 Sep 24; 15(6):937-49.
Score: 0.002
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Selective estrogen receptor modulators 4-hydroxytamoxifen and raloxifene impact the stability and function of SRC-1 and SRC-3 coactivator proteins. Mol Cell Biol. 2004 Jan; 24(1):14-24.
Score: 0.002
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Molecular mechanism of chicken ovalbumin upstream promoter-transcription factor (COUP-TF) actions. Keio J Med. 2003 Sep; 52(3):174-81.
Score: 0.001
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Progesterone and glucocorticoid receptors recruit distinct coactivator complexes and promote distinct patterns of local chromatin modification. Mol Cell Biol. 2003 Jun; 23(11):3763-73.
Score: 0.001
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Regulation of human Clara cell 10 kD protein expression by chicken ovalbumin upstream promoter transcription factors (COUP-TFs). Am J Respir Cell Mol Biol. 2002 Sep; 27(3):273-85.
Score: 0.001
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The epidermis as a bioreactor: topically regulated cutaneous delivery into the circulation. Hum Gene Ther. 2002 Jun 10; 13(9):1075-80.
Score: 0.001
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Coactivator/corepressor ratios modulate PR-mediated transcription by the selective receptor modulator RU486. Proc Natl Acad Sci U S A. 2002 Jun 11; 99(12):7940-4.
Score: 0.001
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Regulation of SRC-3 (pCIP/ACTR/AIB-1/RAC-3/TRAM-1) Coactivator activity by I kappa B kinase. Mol Cell Biol. 2002 May; 22(10):3549-61.
Score: 0.001
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Ligand-inducible transgene regulation for gene therapy. Methods Enzymol. 2002; 346:551-61.
Score: 0.001
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Sequential recruitment of steroid receptor coactivator-1 (SRC-1) and p300 enhances progesterone receptor-dependent initiation and reinitiation of transcription from chromatin. Proc Natl Acad Sci U S A. 2001 Oct 23; 98(22):12426-31.
Score: 0.001
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Physiological function of the orphans GCNF and COUP-TF. Trends Endocrinol Metab. 2001 Aug; 12(6):247-51.
Score: 0.001
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An antiprogestin regulable gene switch for induction of gene expression in vivo. Adv Pharmacol. 2000; 47:343-55.
Score: 0.001
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Molecular mechanisms of androgen-independent growth of human prostate cancer LNCaP-AI cells. Endocrinology. 1999 Nov; 140(11):5054-9.
Score: 0.001
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Steroid receptor coactivator-1 (SRC-1) enhances ligand-dependent and receptor-dependent cell-free transcription of chromatin. Proc Natl Acad Sci U S A. 1999 Aug 17; 96(17):9485-90.
Score: 0.001
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A steroid receptor coactivator, SRA, functions as an RNA and is present in an SRC-1 complex. Cell. 1999 Apr 02; 97(1):17-27.
Score: 0.001
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Nuclear receptor coactivators: multiple enzymes, multiple complexes, multiple functions. J Steroid Biochem Mol Biol. 1999 Apr-Jun; 69(1-6):3-12.
Score: 0.001
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Androgen regulation of the cyclin-dependent kinase inhibitor p21 gene through an androgen response element in the proximal promoter. Mol Endocrinol. 1999 Mar; 13(3):376-84.
Score: 0.001
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The Angelman syndrome-associated protein, E6-AP, is a coactivator for the nuclear hormone receptor superfamily. Mol Cell Biol. 1999 Feb; 19(2):1182-9.
Score: 0.001
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Adenovirus-mediated regulable target gene expression in vivo. Proc Natl Acad Sci U S A. 1999 Jan 19; 96(2):355-60.
Score: 0.001
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Distinct steady-state nuclear receptor coregulator complexes exist in vivo. Proc Natl Acad Sci U S A. 1998 Sep 29; 95(20):11697-702.
Score: 0.001
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The steroid receptor coactivator-1 contains multiple receptor interacting and activation domains that cooperatively enhance the activation function 1 (AF1) and AF2 domains of steroid receptors. J Biol Chem. 1998 May 15; 273(20):12101-8.
Score: 0.001
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Regulation of androgen-dependent prostatic cancer cell growth: androgen regulation of CDK2, CDK4, and CKI p16 genes. Cancer Res. 1997 Oct 15; 57(20):4511-6.
Score: 0.001
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Steroid receptor coactivator-1 is a histone acetyltransferase. Nature. 1997 Sep 11; 389(6647):194-8.
Score: 0.001
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Steroid receptor induction of gene transcription: a two-step model. Proc Natl Acad Sci U S A. 1997 Jul 22; 94(15):7879-84.
Score: 0.001
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Gene silencing by chicken ovalbumin upstream promoter-transcription factor I (COUP-TFI) is mediated by transcriptional corepressors, nuclear receptor-corepressor (N-CoR) and silencing mediator for retinoic acid receptor and thyroid hormone receptor (SMRT). Mol Endocrinol. 1997 Jun; 11(6):714-24.
Score: 0.001
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Role of co-activators and co-repressors in the mechanism of steroid/thyroid receptor action. Recent Prog Horm Res. 1997; 52:141-64; discussion 164-5.
Score: 0.001
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The extreme C terminus of progesterone receptor contains a transcriptional repressor domain that functions through a putative corepressor. Proc Natl Acad Sci U S A. 1996 Oct 29; 93(22):12195-9.
Score: 0.001
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Molecular mechanisms of COUP-TF-mediated transcriptional repression: evidence for transrepression and active repression. Mol Cell Biol. 1996 May; 16(5):2332-40.
Score: 0.001
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Chicken ovalbumin upstream promoter-transcription factors and their regulation. J Steroid Biochem Mol Biol. 1996 Jan; 56(1-6 Spec No):81-5.
Score: 0.001
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The tau 4 activation domain of the thyroid hormone receptor is required for release of a putative corepressor(s) necessary for transcriptional silencing. Mol Cell Biol. 1995 Jan; 15(1):76-86.
Score: 0.001
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A rapid one-step method to purify baculovirus-expressed human estrogen receptor to be used in the analysis of the oxytocin promoter. Gene. 1994 Sep 02; 146(2):285-9.
Score: 0.001
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A regulatory system for use in gene transfer. Proc Natl Acad Sci U S A. 1994 Aug 16; 91(17):8180-4.
Score: 0.001
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Detection of potential ligands for nuclear receptors in cellular extracts. Endocrinology. 1994 Jul; 135(1):248-52.
Score: 0.001
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Spatiotemporal expression patterns of chicken ovalbumin upstream promoter-transcription factors in the developing mouse central nervous system: evidence for a role in segmental patterning of the diencephalon. Proc Natl Acad Sci U S A. 1994 May 10; 91(10):4451-5.
Score: 0.001
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Functional characterization of a unique liver gene promoter. J Biol Chem. 1994 Mar 25; 269(12):9137-46.
Score: 0.001
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Differentiation-specific expression of human keratin 1 is mediated by a composite AP-1/steroid hormone element. J Biol Chem. 1994 Mar 11; 269(10):7443-9.
Score: 0.001
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Developmental regulation of the orphan receptor COUP-TF II gene in spinal motor neurons. Development. 1994 Jan; 120(1):25-36.
Score: 0.001
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Ligand-dependent conformational changes in thyroid hormone and retinoic acid receptors are potentially enhanced by heterodimerization with retinoic X receptor. J Steroid Biochem Mol Biol. 1993 Dec; 46(6):643-61.
Score: 0.001
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Transcriptional activation by the estrogen receptor requires a conformational change in the ligand binding domain. Mol Endocrinol. 1993 Oct; 7(10):1266-74.
Score: 0.001
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Ligand-dependent conformational changes in the progesterone receptor are necessary for events that follow DNA binding. Proc Natl Acad Sci U S A. 1992 Dec 15; 89(24):11750-4.
Score: 0.001
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Kindred S thyroid hormone receptor is an active and constitutive silencer and a repressor for thyroid hormone and retinoic acid responses. Proc Natl Acad Sci U S A. 1992 Nov 15; 89(22):10633-7.
Score: 0.001
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Hormone and antihormone induce distinct conformational changes which are central to steroid receptor activation. J Biol Chem. 1992 Sep 25; 267(27):19513-20.
Score: 0.001
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Members of the steroid hormone receptor superfamily interact with TFIIB (S300-II). J Biol Chem. 1992 Sep 05; 267(25):17617-23.
Score: 0.001
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Ligand and DNA-dependent phosphorylation of human progesterone receptor in vitro. Proc Natl Acad Sci U S A. 1992 Apr 01; 89(7):2664-8.
Score: 0.001
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Hormone activation of baculovirus expressed progesterone receptors. J Biol Chem. 1992 Mar 15; 267(8):5193-8.
Score: 0.001
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Progesterone enhances target gene transcription by receptor free of heat shock proteins hsp90, hsp56, and hsp70. Mol Cell Biol. 1991 Oct; 11(10):4998-5004.
Score: 0.001
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Chicken ovalbumin upstream promoter transcription factor binds to a negative regulatory region in the human immunodeficiency virus type 1 long terminal repeat. J Virol. 1991 Jun; 65(6):2853-60.
Score: 0.001
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The COUP-TFs compose a family of functionally related transcription factors. Gene Expr. 1991; 1(3):207-16.
Score: 0.001
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Identification of a functional intermediate in receptor activation in progesterone-dependent cell-free transcription. Nature. 1990 Jun 07; 345(6275):547-50.
Score: 0.001
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Regulation of in vitro transcription by progesterone receptor. Characterization and kinetic studies. J Biol Chem. 1990 Mar 25; 265(9):5129-34.
Score: 0.001
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The progesterone receptor stimulates cell-free transcription by enhancing the formation of a stable preinitiation complex. Cell. 1990 Jan 26; 60(2):247-57.
Score: 0.001
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Steroid hormone-dependent interaction of human progesterone receptor with its target enhancer element. Mol Endocrinol. 1988 Dec; 2(12):1221-9.
Score: 0.001
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The COUP transcription factor binds to an upstream promoter element of the rat insulin II gene. Mol Cell Biol. 1988 May; 8(5):2070-7.
Score: 0.001
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The studies of COUP transcription factor from HeLa cells: purification and partial characterization. Prog Clin Biol Res. 1988; 284:37-51.
Score: 0.000
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Purification and characterization of chicken ovalbumin upstream promoter transcription factor from HeLa cells. J Biol Chem. 1987 Nov 25; 262(33):16080-6.
Score: 0.000
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Tissue-specific expression of the human alpha 1-antitrypsin gene is controlled by multiple cis-regulatory elements. Nucleic Acids Res. 1987 Oct 26; 15(20):8399-415.
Score: 0.000