Connection

MARGARET SPITZ to Genotype

This is a "connection" page, showing publications MARGARET SPITZ has written about Genotype.
Connection Strength

1.530
  1. Genetic Risk Can Be Decreased: Quitting Smoking Decreases and Delays Lung Cancer for Smokers With High and Low CHRNA5 Risk Genotypes - A Meta-Analysis. EBioMedicine. 2016 Sep; 11:219-226.
    View in: PubMed
    Score: 0.082
  2. Multistage analysis of variants in the inflammation pathway and lung cancer risk in smokers. Cancer Epidemiol Biomarkers Prev. 2012 Jul; 21(7):1213-21.
    View in: PubMed
    Score: 0.061
  3. Variants in inflammation genes are implicated in risk of lung cancer in never smokers exposed to second-hand smoke. Cancer Discov. 2011 Oct; 1(5):420-9.
    View in: PubMed
    Score: 0.058
  4. Mutagen sensitivity and genetic variants in nucleotide excision repair pathway: genotype-phenotype correlation. Cancer Epidemiol Biomarkers Prev. 2007 Oct; 16(10):2065-71.
    View in: PubMed
    Score: 0.045
  5. Combined effects of the p53 and p73 polymorphisms on lung cancer risk. Cancer Epidemiol Biomarkers Prev. 2006 Jan; 15(1):158-61.
    View in: PubMed
    Score: 0.040
  6. CYP2E1 G1532C, NQO1 Pro187Ser, and CYP1B1 Val432Leu polymorphisms are not associated with risk of squamous cell carcinoma of the head and neck. Cancer Epidemiol Biomarkers Prev. 2005 Apr; 14(4):1034-6.
    View in: PubMed
    Score: 0.038
  7. Opposing effects of emphysema, hay fever, and select genetic variants on lung cancer risk. Am J Epidemiol. 2005 Mar 01; 161(5):412-22.
    View in: PubMed
    Score: 0.037
  8. Genetic susceptibility to lung cancer: the role of DNA damage and repair. Cancer Epidemiol Biomarkers Prev. 2003 Aug; 12(8):689-98.
    View in: PubMed
    Score: 0.033
  9. XPA polymorphism associated with reduced lung cancer risk and a modulating effect on nucleotide excision repair capacity. Carcinogenesis. 2003 Mar; 24(3):505-9.
    View in: PubMed
    Score: 0.032
  10. Myeloperoxidase promoter region polymorphism and lung cancer risk. Methods Mol Med. 2003; 75:121-33.
    View in: PubMed
    Score: 0.032
  11. Association between asbestos exposure, cigarette smoking, myeloperoxidase (MPO) genotypes, and lung cancer risk. Am J Ind Med. 2002 Jul; 42(1):29-37.
    View in: PubMed
    Score: 0.031
  12. p53 Genotypes and Haplotypes Associated With Lung Cancer Susceptibility and Ethnicity. J Natl Cancer Inst. 2002 May 01; 94(9):681-90.
    View in: PubMed
    Score: 0.031
  13. Modulation of nucleotide excision repair capacity by XPD polymorphisms in lung cancer patients. Cancer Res. 2001 Feb 15; 61(4):1354-7.
    View in: PubMed
    Score: 0.028
  14. Dietary intake of isothiocyanates: evidence of a joint effect with glutathione S-transferase polymorphisms in lung cancer risk. Cancer Epidemiol Biomarkers Prev. 2000 Oct; 9(10):1017-20.
    View in: PubMed
    Score: 0.027
  15. Deletion in poly(ADP-ribose)polymerase pseudogene and lung cancer risk. Carcinogenesis. 1998 Jan; 19(1):93-8.
    View in: PubMed
    Score: 0.023
  16. Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes. Nat Genet. 2017 Jul; 49(7):1126-1132.
    View in: PubMed
    Score: 0.022
  17. Associations between cytochrome P4502E1 genotype, mutagen sensitivity, cigarette smoking and susceptibility to lung cancer. Carcinogenesis. 1997 May; 18(5):967-73.
    View in: PubMed
    Score: 0.022
  18. Clinical and genetic investigation of a Brazilian family with Huntington's disease. Funct Neurol. 2016 Jul-Sep; 31(3):135-42.
    View in: PubMed
    Score: 0.020
  19. Higher lung cancer risk for younger African-Americans with the Pro/Pro p53 genotype. Carcinogenesis. 1995 Sep; 16(9):2205-8.
    View in: PubMed
    Score: 0.019
  20. Characterization of large structural genetic mosaicism in human autosomes. Am J Hum Genet. 2015 Mar 05; 96(3):487-97.
    View in: PubMed
    Score: 0.019
  21. CYP2A6 reduced activity gene variants confer reduction in lung cancer risk in African American smokers--findings from two independent populations. Carcinogenesis. 2015 Jan; 36(1):99-103.
    View in: PubMed
    Score: 0.018
  22. A race-specific genetic polymorphism in the CYP1A1 gene is not associated with lung cancer in African Americans. Carcinogenesis. 1994 Jun; 15(6):1121-4.
    View in: PubMed
    Score: 0.018
  23. Inflammation-related genetic variations and survival in patients with advanced non-small cell lung cancer receiving first-line chemotherapy. Clin Pharmacol Ther. 2014 Sep; 96(3):360-369.
    View in: PubMed
    Score: 0.018
  24. Genetic variation in the PNPLA3 gene and hepatocellular carcinoma in USA: risk and prognosis prediction. Mol Carcinog. 2013 Nov; 52 Suppl 1:E139-47.
    View in: PubMed
    Score: 0.017
  25. Pilot study of CYP2B6 genetic variation to explore the contribution of nitrosamine activation to lung carcinogenesis. Int J Mol Sci. 2013 Apr 16; 14(4):8381-92.
    View in: PubMed
    Score: 0.016
  26. Hierarchical modeling identifies novel lung cancer susceptibility variants in inflammation pathways among 10,140 cases and 11,012 controls. Hum Genet. 2013 05; 132(5):579-89.
    View in: PubMed
    Score: 0.016
  27. Cigarette experimentation and the population attributable fraction for associated genetic and non-genetic risk factors. PLoS One. 2013; 8(1):e53868.
    View in: PubMed
    Score: 0.016
  28. Association study of nicotinic acetylcholine receptor genes identifies a novel lung cancer susceptibility locus near CHRNA1 in African-Americans. Oncotarget. 2012 Nov; 3(11):1428-38.
    View in: PubMed
    Score: 0.016
  29. Genome-wide association study reveals novel genetic determinants of DNA repair capacity in lung cancer. Cancer Res. 2013 Jan 01; 73(1):256-64.
    View in: PubMed
    Score: 0.016
  30. Roles of genetic variants in the PI3K and RAS/RAF pathways in susceptibility to endometrial cancer and clinical outcomes. J Cancer Res Clin Oncol. 2012 Mar; 138(3):377-85.
    View in: PubMed
    Score: 0.015
  31. A case-control study of a sex-specific association between a 15q25 variant and lung cancer risk. Cancer Epidemiol Biomarkers Prev. 2011 Dec; 20(12):2603-9.
    View in: PubMed
    Score: 0.015
  32. Novel genetic variants in the chromosome 5p15.33 region associate with lung cancer risk. Carcinogenesis. 2011 Oct; 32(10):1493-9.
    View in: PubMed
    Score: 0.015
  33. Relationship between CYP2A6 and CHRNA5-CHRNA3-CHRNB4 variation and smoking behaviors and lung cancer risk. J Natl Cancer Inst. 2011 Sep 07; 103(17):1342-6.
    View in: PubMed
    Score: 0.014
  34. The PhenX Toolkit: get the most from your measures. Am J Epidemiol. 2011 Aug 01; 174(3):253-60.
    View in: PubMed
    Score: 0.014
  35. Genome-wide association study of survival in non-small cell lung cancer patients receiving platinum-based chemotherapy. J Natl Cancer Inst. 2011 May 18; 103(10):817-25.
    View in: PubMed
    Score: 0.014
  36. An analysis of single nucleotide polymorphisms of 125 DNA repair genes in the Texas genome-wide association study of lung cancer with a replication for the XRCC4 SNPs. DNA Repair (Amst). 2011 Apr 03; 10(4):398-407.
    View in: PubMed
    Score: 0.014
  37. Global assessment of genetic variation influencing response to retinoid chemoprevention in head and neck cancer patients. Cancer Prev Res (Phila). 2011 Feb; 4(2):185-93.
    View in: PubMed
    Score: 0.014
  38. Admixture mapping of lung cancer in 1812 African-Americans. Carcinogenesis. 2011 Mar; 32(3):312-7.
    View in: PubMed
    Score: 0.014
  39. MicroRNA-related genetic variations as predictors for risk of second primary tumor and/or recurrence in patients with early-stage head and neck cancer. Carcinogenesis. 2010 Dec; 31(12):2118-23.
    View in: PubMed
    Score: 0.014
  40. Replication of lung cancer susceptibility loci at chromosomes 15q25, 5p15, and 6p21: a pooled analysis from the International Lung Cancer Consortium. J Natl Cancer Inst. 2010 Jul 07; 102(13):959-71.
    View in: PubMed
    Score: 0.013
  41. A functional variant of tandem repeats in human telomerase gene was associated with survival of patients with early stages of non-small cell lung cancer. Clin Cancer Res. 2010 Jul 15; 16(14):3779-85.
    View in: PubMed
    Score: 0.013
  42. A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma. Am J Hum Genet. 2009 11; 85(5):679-91.
    View in: PubMed
    Score: 0.013
  43. Novel susceptibility loci for second primary tumors/recurrence in head and neck cancer patients: large-scale evaluation of genetic variants. Cancer Prev Res (Phila). 2009 Jul; 2(7):617-24.
    View in: PubMed
    Score: 0.013
  44. Genetic variations in cell-cycle pathway and the risk of oral premalignant lesions. Cancer. 2008 Nov 01; 113(9):2488-95.
    View in: PubMed
    Score: 0.012
  45. The influence of tumor necrosis factor-alpha -308 G/A and IL-6 -174 G/C on pain and analgesia response in lung cancer patients receiving supportive care. Cancer Epidemiol Biomarkers Prev. 2008 Nov; 17(11):3262-7.
    View in: PubMed
    Score: 0.012
  46. Familial aggregation of common sequence variants on 15q24-25.1 in lung cancer. J Natl Cancer Inst. 2008 Sep 17; 100(18):1326-30.
    View in: PubMed
    Score: 0.012
  47. ATM sequence variants associate with susceptibility to non-small cell lung cancer. Int J Cancer. 2007 Nov 15; 121(10):2254-9.
    View in: PubMed
    Score: 0.011
  48. Characterizing the cancer genome in lung adenocarcinoma. Nature. 2007 Dec 06; 450(7171):893-8.
    View in: PubMed
    Score: 0.011
  49. Genetic polymorphisms in DNA base-excision repair genes ADPRT, XRCC1, and APE1 and the risk of squamous cell carcinoma of the head and neck. Cancer. 2007 Aug 15; 110(4):867-75.
    View in: PubMed
    Score: 0.011
  50. Potentially functional single nucleotide polymorphisms in the core nucleotide excision repair genes and risk of squamous cell carcinoma of the head and neck. Cancer Epidemiol Biomarkers Prev. 2007 Aug; 16(8):1633-8.
    View in: PubMed
    Score: 0.011
  51. Myeloperoxidase G-463A polymorphism and lung cancer: a HuGE genetic susceptibility to environmental carcinogens pooled analysis. Genet Med. 2007 Feb; 9(2):67-73.
    View in: PubMed
    Score: 0.011
  52. Association of genetic variants of O6-methylguanine-DNA methyltransferase with risk of lung cancer in non-Hispanic Whites. Cancer Epidemiol Biomarkers Prev. 2006 Dec; 15(12):2364-9.
    View in: PubMed
    Score: 0.011
  53. 172G>T variant in the 5' untranslated region of DNA repair gene RAD51 reduces risk of squamous cell carcinoma of the head and neck and interacts with a P53 codon 72 variant. Carcinogenesis. 2007 May; 28(5):988-94.
    View in: PubMed
    Score: 0.011
  54. Meta- and pooled analysis of GSTT1 and lung cancer: a HuGE-GSEC review. Am J Epidemiol. 2006 Dec 01; 164(11):1027-42.
    View in: PubMed
    Score: 0.010
  55. Polymorphisms of STK15 (Aurora-A) gene and lung cancer risk in Caucasians. Carcinogenesis. 2007 Feb; 28(2):350-5.
    View in: PubMed
    Score: 0.010
  56. Evaluation of glutathione S-transferase polymorphisms and mutagen sensitivity as risk factors for the development of second primary tumors in patients previously diagnosed with early-stage head and neck cancer. Cancer. 2006 Jun 15; 106(12):2636-44.
    View in: PubMed
    Score: 0.010
  57. MDM2 gene promoter polymorphisms and risk of lung cancer: a case-control analysis. Carcinogenesis. 2006 Oct; 27(10):2028-33.
    View in: PubMed
    Score: 0.010
  58. Cyclin D1 gene polymorphism as a risk factor for oral premalignant lesions. Carcinogenesis. 2006 Oct; 27(10):2034-7.
    View in: PubMed
    Score: 0.010
  59. Polymorphisms of methionine synthase and methionine synthase reductase and risk of lung cancer: a case-control analysis. Pharmacogenet Genomics. 2005 Aug; 15(8):547-55.
    View in: PubMed
    Score: 0.010
  60. Sex differences in risk of lung cancer associated with methylene-tetrahydrofolate reductase polymorphisms. Cancer Epidemiol Biomarkers Prev. 2005 Jun; 14(6):1477-84.
    View in: PubMed
    Score: 0.009
  61. Methylenetetrahydrofolate reductase polymorphisms and risk of squamous cell carcinoma of the head and neck: a case-control analysis. Int J Cancer. 2005 May 20; 115(1):131-6.
    View in: PubMed
    Score: 0.009
  62. Genetic polymorphisms of p21 are associated with risk of squamous cell carcinoma of the head and neck. Carcinogenesis. 2005 Sep; 26(9):1596-602.
    View in: PubMed
    Score: 0.009
  63. Polymorphisms of methionine synthase and methionine synthase reductase and risk of squamous cell carcinoma of the head and neck: a case-control analysis. Cancer Epidemiol Biomarkers Prev. 2005 May; 14(5):1188-93.
    View in: PubMed
    Score: 0.009
  64. Polymorphisms of vitamin D receptor gene protect against the risk of head and neck cancer. Pharmacogenet Genomics. 2005 Mar; 15(3):159-65.
    View in: PubMed
    Score: 0.009
  65. Thymidylate synthase 5'- and 3'-untranslated region polymorphisms associated with risk and progression of squamous cell carcinoma of the head and neck. Clin Cancer Res. 2004 Dec 01; 10(23):7903-10.
    View in: PubMed
    Score: 0.009
  66. Androgen receptor polymorphisms and risk of biochemical failure among prostatectomy patients. Prostate. 2004 Sep 01; 60(4):343-51.
    View in: PubMed
    Score: 0.009
  67. Assessing the function of genetic variants in candidate gene association studies. Nat Rev Genet. 2004 Aug; 5(8):589-97.
    View in: PubMed
    Score: 0.009
  68. Association between the V109G polymorphism of the p27 gene and the risk and progression of oral squamous cell carcinoma. Clin Cancer Res. 2004 Jun 15; 10(12 Pt 1):3996-4002.
    View in: PubMed
    Score: 0.009
  69. Association of a p73 exon 2 G4C14-to-A4T14 polymorphism with risk of squamous cell carcinoma of the head and neck. Carcinogenesis. 2004 Oct; 25(10):1911-6.
    View in: PubMed
    Score: 0.009
  70. No Association between hOGG1 Ser326Cys polymorphism and risk of squamous cell carcinoma of the head and neck. Cancer Epidemiol Biomarkers Prev. 2004 Jun; 13(6):1081-3.
    View in: PubMed
    Score: 0.009
  71. Polymorphisms of folate metabolic genes and susceptibility to bladder cancer: a case-control study. Carcinogenesis. 2004 Sep; 25(9):1639-47.
    View in: PubMed
    Score: 0.009
  72. An evolutionary perspective on single-nucleotide polymorphism screening in molecular cancer epidemiology. Cancer Res. 2004 Mar 15; 64(6):2251-7.
    View in: PubMed
    Score: 0.009
  73. Comparison of haplotype inference methods using genotypic data from unrelated individuals. Hum Hered. 2004; 58(2):63-8.
    View in: PubMed
    Score: 0.009
  74. p53 codon 72 Arg homozygotes are associated with an increased risk of cutaneous melanoma. J Invest Dermatol. 2003 Dec; 121(6):1510-4.
    View in: PubMed
    Score: 0.009
  75. Fas A670G polymorphism, apoptotic capacity in lymphocyte cultures, and risk of lung cancer. Lung Cancer. 2003 Oct; 42(1):1-8.
    View in: PubMed
    Score: 0.008
  76. Genetic instability in bladder cancer assessed by the comet assay. J Natl Cancer Inst. 2003 Apr 02; 95(7):540-7.
    View in: PubMed
    Score: 0.008
  77. Association between glutathione S-transferase p1 polymorphisms and lung cancer risk in Caucasians: a case-control study. Lung Cancer. 2003 Apr; 40(1):25-32.
    View in: PubMed
    Score: 0.008
  78. Death receptor 4 and bladder cancer risk. Cancer Res. 2003 Mar 15; 63(6):1157-9.
    View in: PubMed
    Score: 0.008
  79. Rapid assessment of repair of ultraviolet DNA damage with a modified host-cell reactivation assay using a luciferase reporter gene and correlation with polymorphisms of DNA repair genes in normal human lymphocytes. Mutat Res. 2002 Nov 30; 509(1-2):165-74.
    View in: PubMed
    Score: 0.008
  80. P53 codon 72 polymorphism and risk of squamous cell carcinoma of the head and neck: a case-control study. Cancer Lett. 2002 Sep 26; 183(2):123-30.
    View in: PubMed
    Score: 0.008
  81. DNA repair gene ERCC1 and ERCC2/XPD polymorphisms and risk of squamous cell carcinoma of the head and neck. Arch Otolaryngol Head Neck Surg. 2002 Sep; 128(9):1084-8.
    View in: PubMed
    Score: 0.008
  82. XPD/ERCC2 EXON 8 Polymorphisms: rarity and lack of significance in risk of squamous cell carcinoma of the head and neck. Oral Oncol. 2002 Jul; 38(5):475-7.
    View in: PubMed
    Score: 0.008
  83. A variant of the DNA repair gene XRCC3 and risk of squamous cell carcinoma of the head and neck: a case-control analysis. Int J Cancer. 2002 Jun 20; 99(6):869-72.
    View in: PubMed
    Score: 0.008
  84. Polymorphism of DNA ligase I and risk of lung cancer--a case-control analysis. Lung Cancer. 2002 Jun; 36(3):243-7.
    View in: PubMed
    Score: 0.008
  85. Modulation of repair of ultraviolet damage in the host-cell reactivation assay by polymorphic XPC and XPD/ERCC2 genotypes. Carcinogenesis. 2002 Feb; 23(2):295-9.
    View in: PubMed
    Score: 0.008
  86. Polymorphic hCHK2/hCds1 codon 84 allele and risk of squamous cell carcinoma of the head and neck--a case-control analysis. Carcinogenesis. 2001 Dec; 22(12):2005-8.
    View in: PubMed
    Score: 0.007
  87. A single nucleotide polymorphism in the matrix metalloproteinase-1 promoter enhances lung cancer susceptibility. Cancer Res. 2001 Nov 01; 61(21):7825-9.
    View in: PubMed
    Score: 0.007
  88. Polymorphisms of 5,10-methylenetetrahydrofolate reductase and risk of gastric cancer in a Chinese population: a case-control study. Int J Cancer. 2001 Sep 20; 95(5):332-6.
    View in: PubMed
    Score: 0.007
  89. An intronic poly (AT) polymorphism of the DNA repair gene XPC and risk of squamous cell carcinoma of the head and neck: a case-control study. Cancer Res. 2001 Apr 15; 61(8):3321-5.
    View in: PubMed
    Score: 0.007
  90. Alcohol dehydrogenase 3 genotype is not associated with risk of squamous cell carcinoma of the oral cavity and pharynx. Cancer Epidemiol Biomarkers Prev. 2001 Mar; 10(3):273-5.
    View in: PubMed
    Score: 0.007
  91. XPD/ERCC2 polymorphisms and risk of head and neck cancer: a case-control analysis. Carcinogenesis. 2000 Dec; 21(12):2219-23.
    View in: PubMed
    Score: 0.007
  92. Ethnic differences in poly(ADP-ribose) polymerase pseudogene genotype distribution and association with lung cancer risk. Carcinogenesis. 1999 Aug; 20(8):1465-9.
    View in: PubMed
    Score: 0.006
  93. Glutathione-S-transferase polymorphisms and risk of squamous-cell carcinoma of the head and neck. Int J Cancer. 1999 Jun 21; 84(3):220-4.
    View in: PubMed
    Score: 0.006
  94. Polymorphisms in the glutathione S-transferase class mu and theta genes interact and increase susceptibility to lung cancer in minority populations (Texas, United States). Cancer Causes Control. 1997 Jul; 8(4):554-9.
    View in: PubMed
    Score: 0.005
  95. Molecular epidemiology and retinoid chemoprevention of head and neck cancer. J Natl Cancer Inst. 1997 Feb 05; 89(3):199-211.
    View in: PubMed
    Score: 0.005
  96. Lung cancer in Mexican-Americans and African-Americans is associated with the wild-type genotype of the NAD(P)H: quinone oxidoreductase polymorphism. Cancer Epidemiol Biomarkers Prev. 1997 Feb; 6(2):87-92.
    View in: PubMed
    Score: 0.005
  97. Ethnic variation in the prevalence of a common NAD(P)H quinone oxidoreductase polymorphism and its implications for anti-cancer chemotherapy. Br J Cancer. 1997; 76(7):852-4.
    View in: PubMed
    Score: 0.005
  98. Glutathione s-transferase genotypes as risk factors for head and neck cancer. Am J Surg. 1995 Nov; 170(5):499-501.
    View in: PubMed
    Score: 0.005
  99. Ethnic differences in the prevalence of the homozygous deleted genotype of glutathione S-transferase theta. Carcinogenesis. 1995 May; 16(5):1243-5.
    View in: PubMed
    Score: 0.005
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.