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PETER HOTEZ to Chagas Disease

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This is a "connection" page, showing publications PETER HOTEZ has written about Chagas Disease.
PETER HOTEZ
Connection Strength
9.365
Chagas Disease
  1. Vaccine-linked chemotherapy improves cardiac structure and function in a mouse model of chronic Chagas disease. Front Cell Infect Microbiol. 2023; 13:1106315.
    View in: PubMed
    Score: 0.592
  2. Preclinical advances and the immunophysiology of a new therapeutic Chagas disease vaccine. Expert Rev Vaccines. 2022 09; 21(9):1185-1203.
    View in: PubMed
    Score: 0.568
  3. A new patient registry for Chagas disease. PLoS Negl Trop Dis. 2020 10; 14(10):e0008418.
    View in: PubMed
    Score: 0.503
  4. In Search of Congenital Chagas Disease in the Sierra Nevada de Santa Marta, Colombia. Am J Trop Med Hyg. 2019 09; 101(3):482-483.
    View in: PubMed
    Score: 0.466
  5. Cysteine mutagenesis improves the production without abrogating antigenicity of a recombinant protein vaccine candidate for human chagas disease. Hum Vaccin Immunother. 2017 03 04; 13(3):621-633.
    View in: PubMed
    Score: 0.382
  6. The BENEFIT Trial: Where Do We Go from Here? PLoS Negl Trop Dis. 2016 Feb; 10(2):e0004343.
    View in: PubMed
    Score: 0.365
  7. The 1899 United States Kissing Bug Epidemic. PLoS Negl Trop Dis. 2015 Dec; 9(12):e0004117.
    View in: PubMed
    Score: 0.361
  8. An unfolding tragedy of Chagas disease in North America. PLoS Negl Trop Dis. 2013; 7(10):e2300.
    View in: PubMed
    Score: 0.311
  9. Global economic burden of Chagas disease: a computational simulation model. Lancet Infect Dis. 2013 Apr; 13(4):342-8.
    View in: PubMed
    Score: 0.296
  10. Modeling the economic value of a Chagas' disease therapeutic vaccine. Hum Vaccin Immunother. 2012 Sep; 8(9):1293-301.
    View in: PubMed
    Score: 0.286
  11. Chagas disease: "the new HIV/AIDS of the Americas". PLoS Negl Trop Dis. 2012; 6(5):e1498.
    View in: PubMed
    Score: 0.282
  12. The neglected tropical diseases of Latin America and the Caribbean: a review of disease burden and distribution and a roadmap for control and elimination. PLoS Negl Trop Dis. 2008 Sep 24; 2(9):e300.
    View in: PubMed
    Score: 0.218
  13. Immunotherapy of TSA-1.C4 or in combination with BNZ confers protection against Trypanosoma cruzi infection with a distinct cytokine response. Vaccine. 2026 Mar 19; 76:128296.
    View in: PubMed
    Score: 0.182
  14. Different responses involving Tfh cells delay parasite-specific antibody production in Trypanosoma cruzi acute experimental models. Front Immunol. 2025; 16:1487317.
    View in: PubMed
    Score: 0.172
  15. Immunopeptidomic MHC-I profiling and immunogenicity testing identifies Tcj2 as a new Chagas disease mRNA vaccine candidate. PLoS Pathog. 2024 Dec; 20(12):e1012764.
    View in: PubMed
    Score: 0.168
  16. Harnessing RNA Technology to Advance Therapeutic Vaccine Antigens against Chagas Disease. ACS Appl Mater Interfaces. 2024 Apr 03; 16(13):15832-15846.
    View in: PubMed
    Score: 0.160
  17. The impact of vaccine-linked chemotherapy on liver health in a mouse model of chronic Trypanosoma cruzi infection. PLoS Negl Trop Dis. 2023 11; 17(11):e0011519.
    View in: PubMed
    Score: 0.156
  18. Localized cardiac small molecule trajectories and persistent chemical sequelae in experimental Chagas disease. Nat Commun. 2023 10 25; 14(1):6769.
    View in: PubMed
    Score: 0.155
  19. Development of chimeric protein as a multivalent vaccine for human Kinetoplastid infections: Chagas disease and leishmaniasis. Vaccine. 2023 08 23; 41(37):5400-5411.
    View in: PubMed
    Score: 0.153
  20. Microbiome Alterations Driven by Trypanosoma cruzi Infection in Two Disjunctive Murine Models. Microbiol Spectr. 2023 06 15; 11(3):e0019923.
    View in: PubMed
    Score: 0.150
  21. A novel multi-epitope recombinant protein elicits an antigen-specific CD8+?T cells response in Trypanosoma cruzi-infected mice. Vaccine. 2022 10 26; 40(45):6445-6449.
    View in: PubMed
    Score: 0.144
  22. Vaccine-linked chemotherapy with a low dose of benznidazole plus a bivalent recombinant protein vaccine prevents the development of cardiac fibrosis caused by Trypanosoma cruzi in chronically-infected BALB/c mice. PLoS Negl Trop Dis. 2022 09; 16(9):e0010258.
    View in: PubMed
    Score: 0.144
  23. Signal Transducer and Activator of Transcription-3 Modulation of Cardiac Pathology in Chronic Chagasic Cardiomyopathy. Front Cell Infect Microbiol. 2021; 11:708325.
    View in: PubMed
    Score: 0.134
  24. Alterations to the Cardiac Metabolome Induced by Chronic T. cruzi Infection Relate to the Degree of Cardiac Pathology. ACS Infect Dis. 2021 06 11; 7(6):1638-1649.
    View in: PubMed
    Score: 0.130
  25. Vaccine-linked chemotherapy induces IL-17 production and reduces cardiac pathology during acute Trypanosoma cruzi infection. Sci Rep. 2021 02 05; 11(1):3222.
    View in: PubMed
    Score: 0.129
  26. Risk of Chronic Cardiomyopathy Among Patients With the Acute Phase or Indeterminate Form of Chagas Disease: A Systematic Review and Meta-analysis. JAMA Netw Open. 2020 08 03; 3(8):e2015072.
    View in: PubMed
    Score: 0.124
  27. TLR4 agonist protects against Trypanosoma cruzi acute lethal infection by decreasing cardiac parasite burdens. Parasite Immunol. 2020 10; 42(10):e12769.
    View in: PubMed
    Score: 0.124
  28. Safety and immunogenicity of a recombinant vaccine against Trypanosoma cruzi in Rhesus macaques. Vaccine. 2020 06 15; 38(29):4584-4591.
    View in: PubMed
    Score: 0.122
  29. Reproductive Outcomes in Rhesus Macaques (Macaca mulatta) with Naturally-acquired Trypanosoma cruzi Infection. Comp Med. 2020 04 01; 70(2):152-159.
    View in: PubMed
    Score: 0.121
  30. The potential economic value of a therapeutic Chagas disease vaccine for pregnant women to prevent congenital transmission. Vaccine. 2020 04 03; 38(16):3261-3270.
    View in: PubMed
    Score: 0.121
  31. Response to `letter to the editor: 'Strategies to enhance access to diagnosis and treatment for Chagas disease patients in Latin America'?. Expert Rev Anti Infect Ther. 2019 09; 17(9):673-675.
    View in: PubMed
    Score: 0.116
  32. Economic value of a therapeutic Chagas vaccine for indeterminate and Chagasic cardiomyopathy patients. Vaccine. 2019 06 19; 37(28):3704-3714.
    View in: PubMed
    Score: 0.114
  33. Strategies to enhance access to diagnosis and treatment for Chagas disease patients in Latin America. Expert Rev Anti Infect Ther. 2019 03; 17(3):145-157.
    View in: PubMed
    Score: 0.112
  34. Covalent vaccination with Trypanosoma cruzi Tc24 induces catalytic antibody production. Parasite Immunol. 2018 Nov; 40(11):e12585.
    View in: PubMed
    Score: 0.109
  35. Production of recombinant TSA-1 and evaluation of its potential for the immuno-therapeutic control of Trypanosoma cruzi infection in mice. Hum Vaccin Immunother. 2019; 15(1):210-219.
    View in: PubMed
    Score: 0.109
  36. Vaccine-Linked Chemotherapy Improves Benznidazole Efficacy for Acute Chagas Disease. Infect Immun. 2018 04; 86(4).
    View in: PubMed
    Score: 0.105
  37. Trypanosoma cruzi vaccine candidate antigens Tc24 and TSA-1 recall memory immune response associated with HLA-A and -B supertypes in Chagasic chronic patients from Mexico. PLoS Negl Trop Dis. 2018 01; 12(1):e0006240.
    View in: PubMed
    Score: 0.104
  38. Ten failings in global neglected tropical diseases control. PLoS Negl Trop Dis. 2017 12; 11(12):e0005896.
    View in: PubMed
    Score: 0.104
  39. Status of vaccine research and development of vaccines for Chagas disease. Vaccine. 2016 06 03; 34(26):2996-3000.
    View in: PubMed
    Score: 0.092
  40. A therapeutic nanoparticle vaccine against Trypanosoma cruzi in a BALB/c mouse model of Chagas disease. Hum Vaccin Immunother. 2016 04 02; 12(4):976-87.
    View in: PubMed
    Score: 0.091
  41. Historical Perspectives on the Epidemiology of Human Chagas Disease in Texas and Recommendations for Enhanced Understanding of Clinical Chagas Disease in the Southern United States. PLoS Negl Trop Dis. 2015 Nov; 9(11):e0003981.
    View in: PubMed
    Score: 0.089
  42. New Vaccines for the World's Poorest People. Annu Rev Med. 2016; 67:405-17.
    View in: PubMed
    Score: 0.088
  43. Expression, purification, immunogenicity, and protective efficacy of a recombinant Tc24 antigen as a vaccine against Trypanosoma cruzi infection in mice. Vaccine. 2015 Aug 26; 33(36):4505-12.
    View in: PubMed
    Score: 0.088
  44. Limited antigenic variation in the Trypanosoma cruzi candidate vaccine antigen TSA-1. Parasite Immunol. 2014 Dec; 36(12):708-12.
    View in: PubMed
    Score: 0.084
  45. Evidence of autochthonous Chagas disease in southeastern Texas. Am J Trop Med Hyg. 2015 Feb; 92(2):325-30.
    View in: PubMed
    Score: 0.083
  46. Development of chagas cardiac manifestations among Texas blood donors. Am J Cardiol. 2015 Jan 01; 115(1):113-7.
    View in: PubMed
    Score: 0.083
  47. Trypanosoma cruzi screening in Texas blood donors, 2008-2012. Epidemiol Infect. 2016 Apr; 144(5):1010-3.
    View in: PubMed
    Score: 0.082
  48. Potential novel risk factors for autochthonous and sylvatic transmission of human Chagas disease in the United States. Parasit Vectors. 2014 Jul 04; 7:311.
    View in: PubMed
    Score: 0.081
  49. Accelerating the development of a therapeutic vaccine for human Chagas disease: rationale and prospects. Expert Rev Vaccines. 2012 Sep; 11(9):1043-55.
    View in: PubMed
    Score: 0.072
  50. A plan to defeat neglected tropical diseases. Sci Am. 2010 Jan; 302(1):90-4, 96.
    View in: PubMed
    Score: 0.060
  51. The unfinished public health agenda of chagas disease in the era of globalization. PLoS Negl Trop Dis. 2009 Jul 07; 3(7):e470.
    View in: PubMed
    Score: 0.058
  52. Location and expression kinetics of Tc24 in different life stages of Trypanosoma cruzi. PLoS Negl Trop Dis. 2021 09; 15(9):e0009689.
    View in: PubMed
    Score: 0.033
  53. Identification of vaccine targets in pathogens and design of a vaccine using computational approaches. Sci Rep. 2021 09 02; 11(1):17626.
    View in: PubMed
    Score: 0.033
  54. Characterization and Stability of Trypanosoma cruzi 24-C4 (Tc24-C4), a Candidate Antigen for a Therapeutic Vaccine Against Chagas Disease. J Pharm Sci. 2018 05; 107(5):1468-1473.
    View in: PubMed
    Score: 0.026
  55. Mutations to Cysteine Residues in the Trypanosoma cruzi B-Cell Superantigen Tc24 Diminish Susceptibility to IgM-Mediated Hydrolysis. J Parasitol. 2017 10; 103(5):579-583.
    View in: PubMed
    Score: 0.025
  56. Impact of vectorborne parasitic neglected tropical diseases on child health. Arch Dis Child. 2016 07; 101(7):640-7.
    View in: PubMed
    Score: 0.023
  57. Identification and Characterization of the Trypanosoma cruzi B-cell Superantigen Tc24. Am J Trop Med Hyg. 2016 Jan; 94(1):114-121.
    View in: PubMed
    Score: 0.022
  58. Neglected parasitic infections in the United States: needs and opportunities. Am J Trop Med Hyg. 2014 May; 90(5):783-785.
    View in: PubMed
    Score: 0.020
  59. Childhood parasitic infections endemic to the United States. Pediatr Clin North Am. 2013 Apr; 60(2):471-85.
    View in: PubMed
    Score: 0.018
  60. Neglected infections of poverty in Texas and the rest of the United States: management and treatment options. Clin Pharmacol Ther. 2012 Aug; 92(2):170-81.
    View in: PubMed
    Score: 0.018
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.