Connection

PETER HOTEZ to Helminth Proteins

This is a "connection" page, showing publications PETER HOTEZ has written about Helminth Proteins.
Connection Strength

5.426
  1. Molecular cloning and characterization of Ac-TMP-2, a tissue inhibitor of metalloproteinase secreted by adult Ancylostoma caninum. Mol Biochem Parasitol. 2008 Dec; 162(2):142-8.
    View in: PubMed
    Score: 0.274
  2. Randomized, placebo-controlled, double-blind trial of the Na-ASP-2 hookworm vaccine in unexposed adults. Vaccine. 2008 May 02; 26(19):2408-17.
    View in: PubMed
    Score: 0.266
  3. Molecular cloning and characterization of Ac-MTP-2, an astacin-like metalloprotease released by adult Ancylostoma caninum. Mol Biochem Parasitol. 2007 Apr; 152(2):132-8.
    View in: PubMed
    Score: 0.245
  4. Expression of the Necator americanus hookworm larval antigen Na-ASP-2 in Pichia pastoris and purification of the recombinant protein for use in human clinical trials. Vaccine. 2005 Sep 15; 23(39):4754-64.
    View in: PubMed
    Score: 0.224
  5. Antibodies against a secreted protein from hookworm larvae reduce the intensity of hookworm infection in humans and vaccinated laboratory animals. FASEB J. 2005 Oct; 19(12):1743-5.
    View in: PubMed
    Score: 0.221
  6. Effect of combining the larval antigens Ancylostoma secreted protein 2 (ASP-2) and metalloprotease 1 (MTP-1) in protecting hamsters against hookworm infection and disease caused by Ancylostoma ceylanicum. Vaccine. 2005 May 02; 23(24):3123-30.
    View in: PubMed
    Score: 0.218
  7. X-ray structure of Na-ASP-2, a pathogenesis-related-1 protein from the nematode parasite, Necator americanus, and a vaccine antigen for human hookworm infection. J Mol Biol. 2005 Feb 25; 346(3):801-14.
    View in: PubMed
    Score: 0.213
  8. Altering the intracellular trafficking of Necator americanus GST-1 antigen yields novel hookworm mRNA vaccine candidates. PLoS Negl Trop Dis. 2025 Jan; 19(1):e0012809.
    View in: PubMed
    Score: 0.213
  9. Cloning, yeast expression, isolation, and vaccine testing of recombinant Ancylostoma-secreted protein (ASP)-1 and ASP-2 from Ancylostoma ceylanicum. J Infect Dis. 2004 Mar 01; 189(5):919-29.
    View in: PubMed
    Score: 0.200
  10. Molecular characterisation of the Ancylostoma-secreted protein family from the adult stage of Ancylostoma caninum. Int J Parasitol. 2003 Aug; 33(9):897-907.
    View in: PubMed
    Score: 0.193
  11. Ac-FAR-1, a 20 kDa fatty acid- and retinol-binding protein secreted by adult Ancylostoma caninum hookworms: gene transcription pattern, ligand binding properties and structural characterisation. Mol Biochem Parasitol. 2003 Jan; 126(1):63-71.
    View in: PubMed
    Score: 0.185
  12. Molecular cloning and characterization of Ac-mep-1, a developmentally regulated gut luminal metalloendopeptidase from adult Ancylostoma caninum hookworms. Mol Biochem Parasitol. 2002 Jan; 119(1):107-16.
    View in: PubMed
    Score: 0.173
  13. [Studies on immunological reaction of the antiserum of recombinant secreted protein from Ancylostoma caninum]. Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 2001; 19(3):166-8.
    View in: PubMed
    Score: 0.161
  14. Protective immunity elicited by the nematode-conserved As37 recombinant protein against Ascaris suum infection. PLoS Negl Trop Dis. 2020 02; 14(2):e0008057.
    View in: PubMed
    Score: 0.152
  15. Hookworm burden reductions in BALB/c mice vaccinated with recombinant Ancylostoma secreted proteins (ASPs) from Ancylostoma duodenale, Ancylostoma caninum and Necator americanus. Vaccine. 2000 Jan 06; 18(11-12):1096-102.
    View in: PubMed
    Score: 0.151
  16. Antibody-dependent reductions in mouse hookworm burden after vaccination with Ancylostoma caninum secreted protein 1. J Infect Dis. 1999 Nov; 180(5):1674-81.
    View in: PubMed
    Score: 0.149
  17. Ancylostoma secreted protein 2: cloning and characterization of a second member of a family of nematode secreted proteins from Ancylostoma caninum. Mol Biochem Parasitol. 1999 Apr 30; 99(2):149-65.
    View in: PubMed
    Score: 0.144
  18. Ancylostoma secreted protein 1 (ASP-1) homologues in human hookworms. Mol Biochem Parasitol. 1999 Jan 05; 98(1):143-9.
    View in: PubMed
    Score: 0.141
  19. Progress in the development of a vaccine against schistosomiasis in China. Int J Infect Dis. 1998 Jan-Mar; 2(3):176-80.
    View in: PubMed
    Score: 0.131
  20. Vaccines for hookworm infection. Pediatr Infect Dis J. 1997 Oct; 16(10):935-40.
    View in: PubMed
    Score: 0.129
  21. Hookworm recombinant protein promotes regulatory T cell responses that suppress experimental asthma. Sci Transl Med. 2016 10 26; 8(362):362ra143.
    View in: PubMed
    Score: 0.121
  22. Molecular approaches to vaccinating against hookworm disease. Pediatr Res. 1996 Oct; 40(4):515-21.
    View in: PubMed
    Score: 0.120
  23. Hookworm: developmental biology of the infectious process. Curr Opin Genet Dev. 1996 Oct; 6(5):618-23.
    View in: PubMed
    Score: 0.120
  24. Ancylostoma caninum anticoagulant peptide: cloning by PCR and expression of soluble, active protein in E. coli. Mol Biochem Parasitol. 1996 Sep; 80(1):113-7.
    View in: PubMed
    Score: 0.120
  25. Cloning and characterization of Ancylostoma-secreted protein. A novel protein associated with the transition to parasitism by infective hookworm larvae. J Biol Chem. 1996 Mar 22; 271(12):6672-8.
    View in: PubMed
    Score: 0.116
  26. Ancylostoma caninum anticoagulant peptide: a hookworm-derived inhibitor of human coagulation factor Xa. Proc Natl Acad Sci U S A. 1995 Jun 20; 92(13):6152-6.
    View in: PubMed
    Score: 0.110
  27. Vaccines to combat river blindness: expression, selection and formulation of vaccines against infection with Onchocerca volvulus in a mouse model. Int J Parasitol. 2014 Aug; 44(9):637-46.
    View in: PubMed
    Score: 0.102
  28. Expression at a 20L scale and purification of the extracellular domain of the Schistosoma mansoni TSP-2 recombinant protein: a vaccine candidate for human intestinal schistosomiasis. Hum Vaccin Immunother. 2013 Nov; 9(11):2342-50.
    View in: PubMed
    Score: 0.096
  29. Biophysical and formulation studies of the Schistosoma mansoni TSP-2 extracellular domain recombinant protein, a lead vaccine candidate antigen for intestinal schistosomiasis. Hum Vaccin Immunother. 2013 Nov; 9(11):2351-61.
    View in: PubMed
    Score: 0.096
  30. Molecular mechanisms of hookworm disease: stealth, virulence, and vaccines. J Allergy Clin Immunol. 2012 Jul; 130(1):13-21.
    View in: PubMed
    Score: 0.090
  31. Generalized urticaria induced by the Na-ASP-2 hookworm vaccine: implications for the development of vaccines against helminths. J Allergy Clin Immunol. 2012 Jul; 130(1):169-76.e6.
    View in: PubMed
    Score: 0.089
  32. Expression, purification, and molecular analysis of the Necator americanus glutathione S-transferase 1 (Na-GST-1): a production process developed for a lead candidate recombinant hookworm vaccine antigen. Protein Expr Purif. 2012 Jun; 83(2):145-51.
    View in: PubMed
    Score: 0.088
  33. Reduction of worm fecundity and canine host blood loss mediates protection against hookworm infection elicited by vaccination with recombinant Ac-16. Clin Vaccine Immunol. 2007 Mar; 14(3):281-7.
    View in: PubMed
    Score: 0.062
  34. Saturation of the secretory pathway by overexpression of a hookworm (Necator americanus) Protein (Na-ASP1). Methods Mol Biol. 2007; 389:65-76.
    View in: PubMed
    Score: 0.061
  35. The impact of concurrent and treated Ancylostoma ceylanicum hookworm infections on the immunogenicity of a recombinant hookworm vaccine in hamsters. J Infect Dis. 2006 Jan 01; 193(1):155-62.
    View in: PubMed
    Score: 0.057
  36. Hookworm: "the great infection of mankind". PLoS Med. 2005 Mar; 2(3):e67.
    View in: PubMed
    Score: 0.054
  37. Variation between ASP-1 molecules from Ancylostoma caninum in China and the United States. J Parasitol. 2000 Feb; 86(1):181-5.
    View in: PubMed
    Score: 0.038
  38. Experimental approaches to the development of a recombinant hookworm vaccine. Immunol Rev. 1999 Oct; 171:163-71.
    View in: PubMed
    Score: 0.037
  39. Advancing a vaccine to prevent human schistosomiasis. Vaccine. 2016 06 03; 34(26):2988-2991.
    View in: PubMed
    Score: 0.029
  40. Anticoagulant repertoire of the hookworm Ancylostoma caninum. Proc Natl Acad Sci U S A. 1996 Mar 05; 93(5):2149-54.
    View in: PubMed
    Score: 0.029
  41. Histochemical alterations of infective third-stage hookworm larvae (L3) in vaccinated mice. Southeast Asian J Trop Med Public Health. 1999 Jun; 30(2):356-64.
    View in: PubMed
    Score: 0.009
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.