KANG LIU to DNA-Binding Proteins
This is a "connection" page, showing publications KANG LIU has written about DNA-Binding Proteins.
Connection Strength
1.646
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Overexpression of TopBP1, a canonical ATR/Chk1 activator, paradoxically hinders ATR/Chk1 activation in cancer. J Biol Chem. 2021 Jan-Jun; 296:100382.
Score: 0.383
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Cell Cycle-Dependent Switch of TopBP1 Functions by Cdk2 and Akt. Mol Cell Biol. 2020 03 30; 40(8).
Score: 0.361
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Mutant p53 perturbs DNA replication checkpoint control through TopBP1 and Treslin. Proc Natl Acad Sci U S A. 2017 05 09; 114(19):E3766-E3775.
Score: 0.294
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Akt switches TopBP1 function from checkpoint activation to transcriptional regulation through phosphoserine binding-mediated oligomerization. Mol Cell Biol. 2013 Dec; 33(23):4685-700.
Score: 0.230
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TopBP1 mediates mutant p53 gain of function through NF-Y and p63/p73. Mol Cell Biol. 2011 Nov; 31(22):4464-81.
Score: 0.200
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A small-molecule inhibitor of TopBP1 exerts anti-MYC activity and synergy with PARP inhibitors. Proc Natl Acad Sci U S A. 2023 10 31; 120(44):e2307793120.
Score: 0.116
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Targeting TopBP1 at a convergent point of multiple oncogenic pathways for cancer therapy. Nat Commun. 2014 Nov 17; 5:5476.
Score: 0.062