Connection

WEEI-CHIN LIN to Nuclear Proteins

This is a "connection" page, showing publications WEEI-CHIN LIN has written about Nuclear Proteins.
Connection Strength

2.901
  1. Overexpression of TopBP1, a canonical ATR/Chk1 activator, paradoxically hinders ATR/Chk1 activation in cancer. J Biol Chem. 2021 Jan-Jun; 296:100382.
    View in: PubMed
    Score: 0.468
  2. Cell Cycle-Dependent Switch of TopBP1 Functions by Cdk2 and Akt. Mol Cell Biol. 2020 03 30; 40(8).
    View in: PubMed
    Score: 0.441
  3. Mutant p53 perturbs DNA replication checkpoint control through TopBP1 and Treslin. Proc Natl Acad Sci U S A. 2017 05 09; 114(19):E3766-E3775.
    View in: PubMed
    Score: 0.360
  4. Targeting TopBP1 at a convergent point of multiple oncogenic pathways for cancer therapy. Nat Commun. 2014 Nov 17; 5:5476.
    View in: PubMed
    Score: 0.304
  5. Akt switches TopBP1 function from checkpoint activation to transcriptional regulation through phosphoserine binding-mediated oligomerization. Mol Cell Biol. 2013 Dec; 33(23):4685-700.
    View in: PubMed
    Score: 0.281
  6. TopBP1 mediates mutant p53 gain of function through NF-Y and p63/p73. Mol Cell Biol. 2011 Nov; 31(22):4464-81.
    View in: PubMed
    Score: 0.244
  7. Regulation of p53 by TopBP1: a potential mechanism for p53 inactivation in cancer. Mol Cell Biol. 2009 May; 29(10):2673-93.
    View in: PubMed
    Score: 0.205
  8. TopBP1 recruits Brg1/Brm to repress E2F1-induced apoptosis, a novel pRb-independent and E2F1-specific control for cell survival. Genes Dev. 2004 Mar 15; 18(6):673-86.
    View in: PubMed
    Score: 0.145
  9. A small-molecule inhibitor of TopBP1 exerts anti-MYC activity and synergy with PARP inhibitors. Proc Natl Acad Sci U S A. 2023 Oct 31; 120(44):e2307793120.
    View in: PubMed
    Score: 0.141
  10. Mismatch repair system decreases cell survival by stabilizing the tetraploid G1 arrest in response to SN-38. Int J Cancer. 2010 Jun 15; 126(12):2813-25.
    View in: PubMed
    Score: 0.056
  11. Regulation of E2F1-induced apoptosis by the nucleolar protein RRP1B. J Biol Chem. 2010 Feb 26; 285(9):6348-63.
    View in: PubMed
    Score: 0.054
  12. MCPH1/BRIT1 cooperates with E2F1 in the activation of checkpoint, DNA repair and apoptosis. EMBO Rep. 2008 Sep; 9(9):907-15.
    View in: PubMed
    Score: 0.049
  13. Regulation of TopBP1 oligomerization by Akt/PKB for cell survival. EMBO J. 2006 Oct 18; 25(20):4795-807.
    View in: PubMed
    Score: 0.043
  14. ATM-mediated stabilization of hMutL DNA mismatch repair proteins augments p53 activation during DNA damage. Mol Cell Biol. 2004 Jul; 24(14):6430-44.
    View in: PubMed
    Score: 0.037
  15. Regulation of E2F1 by BRCT domain-containing protein TopBP1. Mol Cell Biol. 2003 May; 23(9):3287-304.
    View in: PubMed
    Score: 0.034
  16. V(D)J recombination and the cell cycle. Immunol Today. 1995 Jun; 16(6):279-89.
    View in: PubMed
    Score: 0.020
  17. Regulation of V(D)J recombination activator protein RAG-2 by phosphorylation. Science. 1993 May 14; 260(5110):953-9.
    View in: PubMed
    Score: 0.017
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.