STEPHENPFLUGFELDERSTEPHEN PFLUGFELDER29.70508570000000-95.40180870000000167PFLUGFELDER, STEPHENProfessorprns:coAuthorOfcoauthor ofprns:endDateend dateFaculty Rankprns:fullNamefull nameprns:grantAwardedBygrant awarded byprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:physicalNeighborOfphysical neighborprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:principalInvestigatorNameprincipal investigator nameprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:startDatestart dateprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressvivo:address1address line 1vivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provinceAgreementvivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentDivisionGrantvivo:hasResearchArearesearch areasvivo:hasResearcherRoleresearch activitiesvivo:hrJobTitleHR job titleInformation Resourcevivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:personInPositionpositionsPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titleResearcher Rolevivo:researcherRoleOfresearcher role ofRolevivo:roleContributesTocontributes tovivo:sponsorAwardIdsponsor award idrdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonAuthorship 156519625072832Vo RC, Stafeeva K, Aldave AJ, Stulting RD, Moore Q, Pflugfelder SC, Chungfat NC, Holsclaw DS, Margolis TP, Deng SXAmerican journal of ophthalmologyComplications related to a cosmetic eye-whitening procedure. Am J Ophthalmol. 2014 Nov; 158(5):967-73.Am J Ophthalmol2014-07-27T00:00:002014Complications related to a cosmetic eye-whitening procedure.25284773Pflugfelder SC, Karpecki PM, Perez VLThe ocular surfaceTreatment of blepharitis: recent clinical trials. Ocul Surf. 2014 Oct; 12(4):273-84.Ocul Surf2014-07-22T00:00:002014Treatment of blepharitis: recent clinical trials.25288568Coursey TG, Bohat R, Barbosa FL, Pflugfelder SC, de Paiva CSJournal of immunology (Baltimore, Md. : 1950)Desiccating stress-induced chemokine expression in the epithelium is dependent on upregulation of NKG2D/RAE-1 and release of IFN-? in experimental dry eye. J Immunol. 2014 Nov 15; 193(10):5264-72.J Immunol2014-10-06T00:00:002014Desiccating stress-induced chemokine expression in the epithelium is dependent on upregulation of NKG2D/RAE-1 and release of IFN-? in experimental dry eye.25352733Deng R, Su Z, Hua X, Zhang Z, Li DQ, Pflugfelder SCMolecular visionOsmoprotectants suppress the production and activity of matrix metalloproteinases induced by hyperosmolarity in primary human corneal epithelial cells. Mol Vis. 2014; 20:1243-52.Mol Vis2014-09-12T00:00:002014Osmoprotectants suppress the production and activity of matrix metalloproteinases induced by hyperosmolarity in primary human corneal epithelial cells.Authorship 81191Authorship 828111Authorship 832056Authorship 838646Authorship 843319Authorship 865374Authorship 865704Authorship 860441Authorship 920492Authorship 923305Authorship 92893Authorship 914851Authorship 940264Authorship 943708Authorship 972093Authorship 964335Authorship 990761Authorship 97306Authorship 984833Authorship 998392Authorship 1008426Authorship 1018851Authorship 1020313Authorship 1022511Authorship 1022903Authorship 1025692Authorship 1028184Authorship 1037687Authorship 1039136Authorship 106112Authorship 1072501Authorship 1080817Authorship 109732Authorship 111294Authorship 1120855Authorship 1157752Authorship 122046Authorship 129512Authorship 153621Authorship 17917Authorship 179711Authorship 182311Authorship 184542Authorship 194809Authorship 19992Authorship 206643Authorship 223983Authorship 1607027Authorship 1624746Authorship 162998625585134Yuan X, Marcano DC, Shin CS, Hua X, Isenhart LC, Pflugfelder SC, Acharya GACS nanoOcular drug delivery nanowafer with enhanced therapeutic efficacy. ACS Nano. 2015 Feb 24; 9(2):1749-58.ACS Nano2015-01-27T00:00:002015Ocular drug delivery nanowafer with enhanced therapeutic efficacy.25658308Qu Y, Chi W, Hua X, Deng R, Li J, Liu Z, Pflugfelder SC, Li DQPloS oneUnique expression pattern and functional role of periostin in human limbal stem cells. PLoS One. 2015; 10(2):e0117139.PLoS One2015-02-06T00:00:002015Unique expression pattern and functional role of periostin in human limbal stem cells.25889094Bian F, Barbosa FL, Corrales RM, Pelegrino FS, Volpe EA, Pflugfelder SC, de Paiva CSArthritis research & therapyAltered balance of interleukin-13/interferon-gamma contributes to lacrimal gland destruction and secretory dysfunction in CD25 knockout model of Sj?gren's syndrome. Arthritis Res Ther. 2015 Mar 10; 17:53.Arthritis Res Ther2015-03-10T00:00:002015Altered balance of interleukin-13/interferon-gamma contributes to lacrimal gland destruction and secretory dysfunction in CD25 knockout model of Sj?gren's syndrome.Authorship 260183Authorship 271021Authorship 313646Authorship 323241Authorship 338942Authorship 368223Authorship 368571Authorship 372454MD AndersonAuthorship 405603BITAESMAELIBITA ESMAELI8801ESMAELI, BITAProfessorAuthorship 416282Authorship 448852Authorship 490665Authorship 493762Authorship 508623Authorship 530192Authorship 534456Authorship 586076Authorship 586811Authorship 599826Authorship 653959Authorship 68771Authorship 704131Authorship 722068Authorship 744981Authorship 748792Authorship 762651Authorship 794774Authorship 7972612Authorship 814278Authorship 816533Authorship 836061Authorship 846682Authorship 861006Authorship 8626110Authorship 86331Authorship 2793728Authorship 879836Authorship 889263Authorship 889424Authorship 898282Authorship 899656Authorship 922347Authorship 972704Authorship 98158Authorship 9861415Authorship 9944862847623Pflugfelder SC, Suelflow J, Pflugfelder ME, Parke DWAnnals of ophthalmologySerum and vitreous herpes simplex antibodies in noninfected eyes. Ann Ophthalmol. 1988 Sep; 20(9):355-7.Ann Ophthalmol1988-09-01T00:00:001988Serum and vitreous herpes simplex antibodies in noninfected eyes.3062531Buus DR, Pflugfelder SC, Schachter J, Miller D, Forster RKOphthalmologyLymphogranuloma venereum conjunctivitis with a marginal corneal perforation. Ophthalmology. 1988 Jun; 95(6):799-802.Ophthalmology1988-06-01T00:00:001988Lymphogranuloma venereum conjunctivitis with a marginal corneal perforation.3099579Ullman S, Pflugfelder SC, Hughes R, Forster RKAmerican journal of ophthalmologyBacillus cereus panophthalmitis manifesting as an orbital cellulitis. Am J Ophthalmol. 1987 Jan 15; 103(1):105-6.Am J Ophthalmol1987-01-15T00:00:001987Bacillus cereus panophthalmitis manifesting as an orbital cellulitis.QUIANTAMOOREQUIANTA MOORE10312MOORE, QUIANTAAdjunct Assistant Professor3377043Heidemann DG, Pflugfelder SC, Kronish J, Alfonso EC, Dunn SP, Ullman SAmerican journal of ophthalmologyNecrotizing keratitis caused by Capnocytophaga ochracea. Am J Ophthalmol. 1988 Jun 15; 105(6):655-60.Am J Ophthalmol1988-06-15T00:00:001988Necrotizing keratitis caused by Capnocytophaga ochracea.3195669Duerksen KM, Albert DW, Saulson RM, Pflugfelder SCAmerican journal of ophthalmologySoda pop top ophthalmopathy. Am J Ophthalmol. 1988 Dec 15; 106(6):761-2.Am J Ophthalmol1988-12-15T00:00:001988Soda pop top ophthalmopathy.3265776Davis JL, Koidou-Tsiligianni A, Pflugfelder SC, Miller D, Flynn HW, Forster RKOphthalmologyCoagulase-negative staphylococcal endophthalmitis. Increase in antimicrobial resistance. Ophthalmology. 1988 Oct; 95(10):1404-10.Ophthalmology1988-10-01T00:00:001988Coagulase-negative staphylococcal endophthalmitis. Increase in antimicrobial resistance.3277610Pflugfelder SC, Parel JM, Denham D, Mandelbaum SArchives of ophthalmology (Chicago, Ill. : 1960)A suction trephine block for marking donor corneal buttons. Arch Ophthalmol. 1988 Feb; 106(2):276-81.Arch Ophthalmol1988-02-01T00:00:001988A suction trephine block for marking donor corneal buttons.3674189Pflugfelder SC, Saulson R, Ullman SAmerican journal of ophthalmologyPeripheral corneal ulceration in a patient with AIDS-related complex. Am J Ophthalmol. 1987 Nov 15; 104(5):542-3.Am J Ophthalmol1987-11-15T00:00:001987Peripheral corneal ulceration in a patient with AIDS-related complex.3495255Pflugfelder SC, Hern?ndez E, Fliesler SJ, Alvarez J, Pflugfelder ME, Forster RKArchives of ophthalmology (Chicago, Ill. : 1960)Intravitreal vancomycin. Retinal toxicity, clearance, and interaction with gentamicin. Arch Ophthalmol. 1987 Jun; 105(6):831-7.Arch Ophthalmol1987-06-01T00:00:001987Intravitreal vancomycin. Retinal toxicity, clearance, and interaction with gentamicin.3806887Pflugfelder SC, Roussel TJ, Culbertson WWJAMAPrimary Sj?gren's syndrome after infectious mononucleosis. JAMA. 1987 Feb 27; 257(8):1049-50.JAMA1987-02-27T00:00:001987Primary Sj?gren's syndrome after infectious mononucleosis.3808613Pflugfelder SC, Wilhelmus KR, Osato MS, Matoba AY, Font RLOphthalmologyThe autoimmune nature of aqueous tear deficiency. Ophthalmology. 1986 Dec; 93(12):1513-7.Ophthalmology1986-12-01T00:00:001986The autoimmune nature of aqueous tear deficiency.3826245Ullman S, Pflugfelder SCAmerican journal of ophthalmologyA supplemental labeling system for topical medications. Am J Ophthalmol. 1987 Mar 15; 103(3 Pt 1):335.Am J Ophthalmol1987-03-15T00:00:001987A supplemental labeling system for topical medications.7777270Tu EY, Culbertson WW, Pflugfelder SC, Huang A, Chodosh JCOphthalmologyTherapy of nonnecrotizing anterior scleritis with subconjunctival corticosteroid injection. Ophthalmology. 1995 May; 102(5):718-24.Ophthalmology1995-05-01T00:00:001995Therapy of nonnecrotizing anterior scleritis with subconjunctival corticosteroid injection.26184051Coursey TG, Henriksson JT, Marcano DC, Shin CS, Isenhart LC, Ahmed F, De Paiva CS, Pflugfelder SC, Acharya GJournal of controlled release : official journal of the Controlled Release SocietyDexamethasone nanowafer as an effective therapy for dry eye disease. J Control Release. 2015 Sep 10; 213:168-174.J Control Release2015-07-13T00:00:002015Dexamethasone nanowafer as an effective therapy for dry eye disease.8030548Pflugfelder SC, Crouse CA, Atherton SSAdvances in experimental medicine and biologyEpstein-Barr virus and the lacrimal gland pathology of Sj?gren's syndrome. Adv Exp Med Biol. 1994; 350:641-6.Adv Exp Med Biol1994-01-01T00:00:001994Epstein-Barr virus and the lacrimal gland pathology of Sj?gren's syndrome.8371924Culbertson WW, Huang AJ, Mandelbaum SH, Pflugfelder SC, Boozalis GT, Miller DOphthalmologyEffective treatment of phlyctenular keratoconjunctivitis with oral tetracycline. Ophthalmology. 1993 Sep; 100(9):1358-66.Ophthalmology1993-09-01T00:00:001993Effective treatment of phlyctenular keratoconjunctivitis with oral tetracycline.8670763Gupta A, Monroy D, Ji Z, Yoshino K, Huang A, Pflugfelder SCCurrent eye researchTransforming growth factor beta-1 and beta-2 in human tear fluid. Curr Eye Res. 1996 Jun; 15(6):605-14.Curr Eye Res1996-06-01T00:00:001996Transforming growth factor beta-1 and beta-2 in human tear fluid.6501 Fannin StHouston, 77030TX7743800Chodosh J, Miller D, Stroop WG, Pflugfelder SCCorneaAdenovirus epithelial keratitis. Cornea. 1995 Mar; 14(2):167-74.Cornea1995-03-01T00:00:001995Adenovirus epithelial keratitis.8942882Scott IU, Flynn HW, Feuer W, Pflugfelder SC, Alfonso EC, Forster RK, Miller DOphthalmologyEndophthalmitis associated with microbial keratitis. Ophthalmology. 1996 Nov; 103(11):1864-70.Ophthalmology1996-11-01T00:00:001996Endophthalmitis associated with microbial keratitis.8925660Heigle TJ, Pflugfelder SCCorneaAqueous tear production in patients with neurotrophic keratitis. Cornea. 1996 Mar; 15(2):135-8.Cornea1996-03-01T00:00:001996Aqueous tear production in patients with neurotrophic keratitis.9071524Hoft RH, Pflugfelder SC, Forster RK, Ullman S, Polack FM, Schiff ERCorneaClinical evidence for hepatitis B transmission resulting from corneal transplantation. Cornea. 1997 Mar; 16(2):132-7.Cornea1997-03-01T00:00:001997Clinical evidence for hepatitis B transmission resulting from corneal transplantation.9071540Barton K, Miller D, Pflugfelder SCCorneaCorneal chromoblastomycosis. Cornea. 1997 Mar; 16(2):235-9.Cornea1997-03-01T00:00:001997Corneal chromoblastomycosis.9373119Barton K, Monroy DC, Nava A, Pflugfelder SCOphthalmologyInflammatory cytokines in the tears of patients with ocular rosacea. Ophthalmology. 1997 Nov; 104(11):1868-74.Ophthalmology1997-11-01T00:00:001997Inflammatory cytokines in the tears of patients with ocular rosacea.9436879Pflugfelder SC, Tseng SC, Sanabria O, Kell H, Garcia CG, Felix C, Feuer W, Reis BLCorneaEvaluation of subjective assessments and objective diagnostic tests for diagnosing tear-film disorders known to cause ocular irritation. Cornea. 1998 Jan; 17(1):38-56.Cornea1998-01-01T00:00:001998Evaluation of subjective assessments and objective diagnostic tests for diagnosing tear-film disorders known to cause ocular irritation.8056525Jones DT, Monroy D, Ji Z, Atherton SS, Pflugfelder SCInvestigative ophthalmology & visual scienceSj?gren's syndrome: cytokine and Epstein-Barr viral gene expression within the conjunctival epithelium. Invest Ophthalmol Vis Sci. 1994 Aug; 35(9):3493-504.Invest Ophthalmol Vis Sci1994-08-01T00:00:001994Sj?gren's syndrome: cytokine and Epstein-Barr viral gene expression within the conjunctival epithelium.9220241Nava A, Barton K, Monroy DC, Pflugfelder SCCorneaThe effects of age, gender, and fluid dynamics on the concentration of tear film epidermal growth factor. Cornea. 1997 Jul; 16(4):430-8.Cornea1997-07-01T00:00:001997The effects of age, gender, and fluid dynamics on the concentration of tear film epidermal growth factor.8238218Mao LK, Flynn HW, Miller D, Pflugfelder SCAmerican journal of ophthalmologyEndophthalmitis caused by Staphylococcus aureus. Am J Ophthalmol. 1993 Nov 15; 116(5):584-9.Am J Ophthalmol1993-11-15T00:00:001993Endophthalmitis caused by Staphylococcus aureus.9395874Gupta A, Heigle T, Pflugfelder SCCorneaNasolacrimal stimulation of aqueous tear production. Cornea. 1997 Nov; 16(6):645-8.Cornea1997-11-01T00:00:001997Nasolacrimal stimulation of aqueous tear production.1328982Simon MW, Miller D, Pflugfelder SC, Murchison JF, Huang AJ, Atherton SSOphthalmologyComparison of immunocytology to tissue culture for diagnosis of presumed herpesvirus dendritic epithelial keratitis. Ophthalmology. 1992 Sep; 99(9):1408-13.Ophthalmology1992-09-01T00:00:001992Comparison of immunocytology to tissue culture for diagnosis of presumed herpesvirus dendritic epithelial keratitis.10201607Marsh P, Pflugfelder SCOphthalmologyTopical nonpreserved methylprednisolone therapy for keratoconjunctivitis sicca in Sj?gren syndrome. Ophthalmology. 1999 Apr; 106(4):811-6.Ophthalmology1999-04-01T00:00:001999Topical nonpreserved methylprednisolone therapy for keratoconjunctivitis sicca in Sj?gren syndrome.8394294Pflugfelder SC, Crouse CA, Atherton SSInternational ophthalmology clinicsOphthalmic manifestations of Epstein-Barr virus infection. Int Ophthalmol Clin. 1993; 33(1):95-101.Int Ophthalmol Clin1993-01-01T00:00:001993Ophthalmic manifestations of Epstein-Barr virus infection.10387469Pflugfelder SCCurrent opinion in ophthalmologyAdvances in the diagnosis and management of keratoconjunctivitis sicca. Curr Opin Ophthalmol. 1998 Aug; 9(4):50-3.Curr Opin Ophthalmol1998-08-01T00:00:001998Advances in the diagnosis and management of keratoconjunctivitis sicca.9634922Barton K, Nava A, Monroy DC, Pflugfelder SCAdvances in experimental medicine and biologyCytokines and tear function in ocular surface disease. Adv Exp Med Biol. 1998; 438:461-9.Adv Exp Med Biol1998-01-01T00:00:001998Cytokines and tear function in ocular surface disease.10647727Liu Z, Pflugfelder SCOphthalmologyThe effects of long-term contact lens wear on corneal thickness, curvature, and surface regularity. Ophthalmology. 2000 Jan; 107(1):105-11.Ophthalmology2000-01-01T00:00:002000The effects of long-term contact lens wear on corneal thickness, curvature, and surface regularity.10764856Liu Z, Carvajal M, Carothers Carraway CA, Carraway KL, Pflugfelder SCAmerican journal of ophthalmologyIncreased expression of the type 1 growth factor receptor family in the conjunctival epithelium of patients with keratoconjunctivitis sicca. Am J Ophthalmol. 2000 Apr; 129(4):472-80.Am J Ophthalmol2000-04-01T00:00:002000Increased expression of the type 1 growth factor receptor family in the conjunctival epithelium of patients with keratoconjunctivitis sicca.10798646Pflugfelder SC, Liu Z, Monroy D, Li DQ, Carvajal ME, Price-Schiavi SA, Idris N, Solomon A, Perez A, Carraway KLInvestigative ophthalmology & visual scienceDetection of sialomucin complex (MUC4) in human ocular surface epithelium and tear fluid. Invest Ophthalmol Vis Sci. 2000 May; 41(6):1316-26.Invest Ophthalmol Vis Sci2000-05-01T00:00:002000Detection of sialomucin complex (MUC4) in human ocular surface epithelium and tear fluid.Authorship 2921256Authorship 2955869Authorship 2959395Authorship 2959996Authorship 2964763Authorship 2967973Authorship 2971846Authorship 29824612Authorship 2986705Authorship 2988867Authorship 2998865Authorship 30140019Authorship 3022621Authorship 3026527Authorship 3037978Authorship 3038895Authorship 305817510928778Wang MX, Shen DJ, Liu JC, Pflugfelder SC, Alfonso EC, Forster RKCorneaRecurrent fungal keratitis and endophthalmitis. Cornea. 2000 Jul; 19(4):558-60.Cornea2000-07-01T00:00:002000Recurrent fungal keratitis and endophthalmitis.25271595Hua X, Su Z, Deng R, Lin J, Li DQ, Pflugfelder SCCurrent eye researchEffects of L-carnitine, erythritol and betaine on pro-inflammatory markers in primary human corneal epithelial cells exposed to hyperosmotic stress. Curr Eye Res. 2015 Jul; 40(7):657-67.Curr Eye Res2014-10-01T00:00:002014Effects of L-carnitine, erythritol and betaine on pro-inflammatory markers in primary human corneal epithelial cells exposed to hyperosmotic stress.25758816You IC, Bian F, Volpe EA, de Paiva CS, Pflugfelder SCInvestigative ophthalmology & visual scienceAge-Related Conjunctival Disease in the C57BL/6.NOD-Aec1Aec2 Mouse Model of Sj?gren Syndrome Develops Independent of Lacrimal Dysfunction. Invest Ophthalmol Vis Sci. 2015 Apr; 56(4):2224-33.Invest Ophthalmol Vis Sci2015-04-01T00:00:002015Age-Related Conjunctival Disease in the C57BL/6.NOD-Aec1Aec2 Mouse Model of Sj?gren Syndrome Develops Independent of Lacrimal Dysfunction.25772203You IC, Coursey TG, Bian F, Barbosa FL, de Paiva CS, Pflugfelder SCArchivum immunologiae et therapiae experimentalisMacrophage Phenotype in the Ocular Surface of Experimental Murine Dry Eye Disease. Arch Immunol Ther Exp (Warsz). 2015 Aug; 63(4):299-304.Arch Immunol Ther Exp (Warsz)2015-03-13T00:00:002015Macrophage Phenotype in the Ocular Surface of Experimental Murine Dry Eye Disease.25868759Moore QL, De Paiva CS, Pflugfelder SCAmerican journal of ophthalmologyEffects of Dry Eye Therapies on Environmentally Induced Ocular Surface Disease. Am J Ophthalmol. 2015 Jul; 160(1):135-42.e1.Am J Ophthalmol2015-04-11T00:00:002015Effects of Dry Eye Therapies on Environmentally Induced Ocular Surface Disease.25881996Foulks GN, Forstot SL, Donshik PC, Forstot JZ, Goldstein MH, Lemp MA, Nelson JD, Nichols KK, Pflugfelder SC, Tanzer JM, Asbell P, Hammitt K, Jacobs DSThe ocular surfaceClinical guidelines for management of dry eye associated with Sj?gren disease. Ocul Surf. 2015 Apr; 13(2):118-32.Ocul Surf2015-01-15T00:00:002015Clinical guidelines for management of dry eye associated with Sj?gren disease.26024535Deng R, Hua X, Li J, Chi W, Zhang Z, Lu F, Zhang L, Pflugfelder SC, Li DQPloS oneOxidative stress markers induced by hyperosmolarity in primary human corneal epithelial cells. PLoS One. 2015; 10(5):e0126561.PLoS One2015-05-29T00:00:002015Oxidative stress markers induced by hyperosmolarity in primary human corneal epithelial cells.26039076Hua X, Yuan X, Li Z, Coursey TG, Pflugfelder SC, Li DQPloS oneA Novel Innate Response of Human Corneal Epithelium to Heat-killed Candida albicans by Producing Peptidoglycan Recognition Proteins. PLoS One. 2015; 10(6):e0128039.PLoS One2015-06-03T00:00:002015A Novel Innate Response of Human Corneal Epithelium to Heat-killed Candida albicans by Producing Peptidoglycan Recognition Proteins.26132778Tukler Henriksson J, Coursey TG, Corry DB, De Paiva CS, Pflugfelder SCInvestigative ophthalmology & visual scienceIL-13 Stimulates Proliferation and Expression of Mucin and Immunomodulatory Genes in Cultured Conjunctival Goblet Cells. Invest Ophthalmol Vis Sci. 2015 Jul; 56(8):4186-97.Invest Ophthalmol Vis Sci2015-07-01T00:00:002015IL-13 Stimulates Proliferation and Expression of Mucin and Immunomodulatory Genes in Cultured Conjunctival Goblet Cells.26204109Zhang L, Su Z, Zhang Z, Lin J, Li DQ, Pflugfelder SCJAMA ophthalmologyEffects of azithromycin on gene expression profiles of proinflammatory and anti-inflammatory mediators in the eyelid margin and conjunctiva of patients with meibomian gland disease. JAMA Ophthalmol. 2015 Oct; 133(10):1117-23.JAMA Ophthalmol2015-10-01T00:00:002015Effects of azithromycin on gene expression profiles of proinflammatory and anti-inflammatory mediators in the eyelid margin and conjunctiva of patients with meibomian gland disease.26225631Bian F, Pelegrino FS, Pflugfelder SC, Volpe EA, Li DQ, de Paiva CSInvestigative ophthalmology & visual scienceDesiccating Stress-Induced MMP Production and Activity Worsens Wound Healing in Alkali-Burned Corneas. Invest Ophthalmol Vis Sci. 2015 Jul; 56(8):4908-18.Invest Ophthalmol Vis Sci2015-07-01T00:00:002015Desiccating Stress-Induced MMP Production and Activity Worsens Wound Healing in Alkali-Burned Corneas.26255576Rahman EZ, Lam PK, Chu CK, Moore Q, Pflugfelder SCAmerican journal of ophthalmologyCorneal Sensitivity in Tear Dysfunction and its Correlation With Clinical Parameters and Blink Rate. Am J Ophthalmol. 2015 Nov; 160(5):858-866.e5.Am J Ophthalmol2015-08-06T00:00:002015Corneal Sensitivity in Tear Dysfunction and its Correlation With Clinical Parameters and Blink Rate.26284556Hua X, Deng R, Li J, Chi W, Su Z, Lin J, Pflugfelder SC, Li DQInvestigative ophthalmology & visual scienceProtective Effects of L-Carnitine Against Oxidative Injury by Hyperosmolarity in Human Corneal Epithelial Cells. Invest Ophthalmol Vis Sci. 2015 Aug; 56(9):5503-11.Invest Ophthalmol Vis Sci2015-08-01T00:00:002015Protective Effects of L-Carnitine Against Oxidative Injury by Hyperosmolarity in Human Corneal Epithelial Cells.26348638Krauss AH, Corrales RM, Pelegrino FS, Tukler-Henriksson J, Pflugfelder SC, de Paiva CSInvestigative ophthalmology & visual scienceImprovement of Outcome Measures of Dry Eye by a Novel Integrin Antagonist in the Murine Desiccating Stress Model. Invest Ophthalmol Vis Sci. 2015 Sep; 56(10):5888-95.Invest Ophthalmol Vis Sci2015-09-01T00:00:002015Improvement of Outcome Measures of Dry Eye by a Novel Integrin Antagonist in the Murine Desiccating Stress Model.26402857Bauskar A, Mack WJ, Mauris J, Arg?eso P, Heur M, Nagel BA, Kolar GR, Gleave ME, Nakamura T, Kinoshita S, Moradian-Oldak J, Panjwani N, Pflugfelder SC, Wilson MR, Fini ME, Jeong SPloS oneClusterin Seals the Ocular Surface Barrier in Mouse Dry Eye. PLoS One. 2015; 10(9):e0138958.PLoS One2015-09-24T00:00:002015Clusterin Seals the Ocular Surface Barrier in Mouse Dry Eye.26549248Kohanim S, Palioura S, Saeed HN, Akpek EK, Amescua G, Basu S, Blomquist PH, Bouchard CS, Dart JK, Gai X, Gomes JA, Gregory DG, Iyer G, Jacobs DS, Johnson AJ, Kinoshita S, Mantagos IS, Mehta JS, Perez VL, Pflugfelder SC, Sangwan VS, Sippel KC, Sotozono C, Srinivasan B, Tan DT, Tandon R, Tseng SC, Ueta M, Chodosh JThe ocular surfaceStevens-Johnson Syndrome/Toxic Epidermal Necrolysis--A Comprehensive Review and Guide to Therapy. I. Systemic Disease. Ocul Surf. 2016 Jan; 14(1):2-19.Ocul Surf2015-11-05T00:00:002015Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis--A Comprehensive Review and Guide to Therapy. I. Systemic Disease.26618646Pflugfelder SC, De Paiva CS, Moore QL, Volpe EA, Li DQ, Gumus K, Zaheer ML, Corrales RMInvestigative ophthalmology & visual scienceAqueous Tear Deficiency Increases Conjunctival Interferon-? (IFN-?) 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Curr Eye Res. 1996 Jun; 15(6):615-24.Curr Eye Res1996-06-01T00:00:001996Production and secretion of transforming growth factor beta (TGF-beta) by the human lacrimal gland.11009316Pflugfelder SC, Solomon A, Stern MECorneaThe diagnosis and management of dry eye: a twenty-five-year review. Cornea. 2000 Sep; 19(5):644-9.Cornea2000-09-01T00:00:002000The diagnosis and management of dry eye: a twenty-five-year review.9820935Stern ME, Beuerman RW, Fox RI, Gao J, Mircheff AK, Pflugfelder SCCorneaThe pathology of dry eye: the interaction between the ocular surface and lacrimal glands. Cornea. 1998 Nov; 17(6):584-9.Cornea1998-11-01T00:00:001998The pathology of dry eye: the interaction between the ocular surface and lacrimal glands.1497532Pflugfelder SC, Roussel TJ, Denham D, Feuer W, Mandelbaum S, Parel JMArchives of ophthalmology (Chicago, Ill. : 1960)Photogrammetric analysis of corneal trephination. 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Invest Ophthalmol Vis Sci. 2010 Feb; 51(2):844-9.Invest Ophthalmol Vis Sci2009-10-08T00:00:002009Association between high tear epidermal growth factor levels and corneal subepithelial fibrosis in dry eye conditions.19878594De Paiva CS, Yoon KC, Pangelinan SB, Pham S, Puthenparambil LM, Chuang EY, Farley WJ, Stern ME, Li DQ, Pflugfelder SCJournal of inflammation (London, England)Cleavage of functional IL-2 receptor alpha chain (CD25) from murine corneal and conjunctival epithelia by MMP-9. J Inflamm (Lond). 2009 Oct 31; 6:31.J Inflamm (Lond)2009-10-31T00:00:002009Cleavage of functional IL-2 receptor alpha chain (CD25) from murine corneal and conjunctival epithelia by MMP-9.19965821Rao K, Leveque C, Pflugfelder SCThe British journal of ophthalmologyCorneal nerve regeneration in neurotrophic keratopathy following autologous plasma therapy. Br J Ophthalmol. 2010 May; 94(5):584-91.Br J Ophthalmol2009-12-03T00:00:002009Corneal nerve regeneration in neurotrophic keratopathy following autologous plasma therapy.20505191Chen Z, Li Z, Basti S, Farley WJ, Pflugfelder SCInvestigative ophthalmology & visual scienceAltered morphology and function of the lacrimal functional unit in protein kinase C{alpha} knockout mice. Invest Ophthalmol Vis Sci. 2010 Nov; 51(11):5592-600.Invest Ophthalmol Vis Sci2010-05-26T00:00:002010Altered morphology and function of the lacrimal functional unit in protein kinase C{alpha} knockout mice.20566743Rahimy E, Pitcher JD, Pangelinan SB, Chen W, Farley WJ, Niederkorn JY, Stern ME, Li DQ, Pflugfelder SC, De Paiva CSThe American journal of pathologySpontaneous autoimmune dacryoadenitis in aged CD25KO mice. Am J Pathol. 2010 Aug; 177(2):744-53.Am J Pathol2010-06-21T00:00:002010Spontaneous autoimmune dacryoadenitis in aged CD25KO mice.20631241Gumus K, Crockett CH, Rao K, Yeu E, Weikert MP, Shirayama M, Hada S, Pflugfelder SCInvestigative ophthalmology & visual scienceNoninvasive assessment of tear stability with the tear stability analysis system in tear dysfunction patients. Invest Ophthalmol Vis Sci. 2011 Jan; 52(1):456-61.Invest Ophthalmol Vis Sci2011-01-21T00:00:002011Noninvasive assessment of tear stability with the tear stability analysis system in tear dysfunction patients.Authorship 101157321820713Li DQ, Zhang L, Pflugfelder SC, De Paiva CS, Zhang X, Zhao G, Zheng X, Su Z, Qu YThe Journal of allergy and clinical immunologyShort ragweed pollen triggers allergic inflammation through Toll-like receptor 4-dependent thymic stromal lymphopoietin/OX40 ligand/OX40 signaling pathways. J Allergy Clin Immunol. 2011 Dec; 128(6):1318-1325.e2.J Allergy Clin Immunol2011-08-06T00:00:002011Short ragweed pollen triggers allergic inflammation through Toll-like receptor 4-dependent thymic stromal lymphopoietin/OX40 ligand/OX40 signaling pathways.21843497Zhang X, Chen W, De Paiva CS, Volpe EA, Gandhi NB, Farley WJ, Li DQ, Niederkorn JY, Stern ME, Pflugfelder SCThe American journal of pathologyDesiccating stress induces CD4+ T-cell-mediated Sj?gren's syndrome-like corneal epithelial apoptosis via activation of the extrinsic apoptotic pathway by interferon-?. Am J Pathol. 2011 Oct; 179(4):1807-14.Am J Pathol2011-08-16T00:00:002011Desiccating stress induces CD4+ T-cell-mediated Sj?gren's syndrome-like corneal epithelial apoptosis via activation of the extrinsic apoptotic pathway by interferon-?.22257864de Paiva CS, Schwartz CE, Gj?rstrup P, Pflugfelder SCCorneaResolvin E1 (RX-10001) reduces corneal epithelial barrier disruption and protects against goblet cell loss in a murine model of dry eye. Cornea. 2012 Nov; 31(11):1299-303.Cornea2012-11-01T00:00:002012Resolvin E1 (RX-10001) reduces corneal epithelial barrier disruption and protects against goblet cell loss in a murine model of dry eye.22723892Lu R, Bian F, Lin J, Su Z, Qu Y, Pflugfelder SC, Li DQPloS oneIdentification of human fibroblast cell lines as a feeder layer for human corneal epithelial regeneration. PLoS One. 2012; 7(6):e38825.PLoS One2012-06-18T00:00:002012Identification of human fibroblast cell lines as a feeder layer for human corneal epithelial regeneration.23218704Ling JD, Gire A, Pflugfelder SCAmerican journal of ophthalmologyPROSE therapy used to minimize corneal trauma in patients with corneal epithelial defects. Am J Ophthalmol. 2013 Apr; 155(4):615-619, 619.e1-2.Am J Ophthalmol2012-12-04T00:00:002012PROSE therapy used to minimize corneal trauma in patients with corneal epithelial defects.Authorship 8792701Authorship 8802412Authorship 8803317Authorship 8807695Authorship 8807855Authorship 8820195Authorship 8822415Authorship 8831057Authorship 106355428701781Li J, Xiao Y, Coursey TG, Chen X, Deng R, Lu F, Pflugfelder SC, Li DQScientific reportsIdentification for Differential Localization of Putative Corneal Epithelial Stem Cells in Mouse and Human. Sci Rep. 2017 07 12; 7(1):5169.Sci Rep2017-07-12T00:00:002017Identification for Differential Localization of Putative Corneal Epithelial Stem Cells in Mouse and Human.29055361Pflugfelder SC, de Paiva CSOphthalmologyThe Pathophysiology of Dry Eye Disease: What We Know and Future Directions for Research. Ophthalmology. 2017 11; 124(11S):S4-S13.Ophthalmology2017-11-01T00:00:002017The Pathophysiology of Dry Eye Disease: What We Know and Future Directions for Research.29284427McDonnell PJ, Pflugfelder SC, Stern ME, Hardten DR, Conway T, Villanueva L, Hollander DABMC ophthalmologyStudy design and baseline findings from the progression of ocular findings (PROOF) natural history study of dry eye. BMC Ophthalmol. 2017 Dec 28; 17(1):265.BMC Ophthalmol2017-12-28T00:00:002017Study design and baseline findings from the progression of ocular findings (PROOF) natural history study of dry eye.29407221Stepp MA, Pal-Ghosh S, Tadvalkar G, Williams A, Pflugfelder SC, de Paiva CSExperimental eye researchReduced intraepithelial corneal nerve density and sensitivity accompany desiccating stress and aging in C57BL/6 mice. Exp Eye Res. 2018 04; 169:91-98.Exp Eye Res2018-01-31T00:00:002018Reduced intraepithelial corneal nerve density and sensitivity accompany desiccating stress and aging in C57BL/6 mice.29415888Ko BY, Xiao Y, Barbosa FL, de Paiva CS, Pflugfelder SCJCI insightGoblet cell loss abrogates ocular surface immune tolerance. JCI Insight. 2018 02 08; 3(3).JCI Insight2018-02-08T00:00:002018Goblet cell loss abrogates ocular surface immune tolerance.29425812Parra AS, Roth BM, Nguyen TM, Wang L, Pflugfelder SC, Al-Mohtaseb ZThe ocular surfaceAssessment of the Prosthetic Replacement of Ocular Surface Ecosystem (PROSE) scleral lens on visual acuity for corneal irregularity and ocular surface disease. Ocul Surf. 2018 04; 16(2):254-258.Ocul Surf2018-02-06T00:00:002018Assessment of the Prosthetic Replacement of Ocular Surface Ecosystem (PROSE) scleral lens on visual acuity for corneal irregularity and ocular surface disease.29497112Yang J, Chandwani R, Gopinatth V, Boyce T, Pflugfelder SC, Huang D, Liu GScientific reportsNear-infrared laser thermal conjunctivoplasty. Sci Rep. 2018 03 01; 8(1):3863.Sci Rep2018-03-01T00:00:002018Near-infrared laser thermal conjunctivoplasty.29438346Wang C, Zaheer M, Bian F, Quach D, Swennes AG, Britton RA, Pflugfelder SC, de Paiva CSInternational journal of molecular sciencesSj?gren-Like Lacrimal Keratoconjunctivitis in Germ-Free Mice. Int J Mol Sci. 2018 Feb 13; 19(2).Int J Mol Sci2018-02-13T00:00:002018Sj?gren-Like Lacrimal Keratoconjunctivitis in Germ-Free Mice.Authorship 10639432674411Thompson KP, Barraquer E, Parel JM, Loertscher H, Pflugfelder S, Roussel T, Holland S, Hanna KJournal of cataract and refractive surgeryPotential use of lasers for penetrating keratoplasty. J Cataract Refract Surg. 1989 Jul; 15(4):397-403.J Cataract Refract Surg1989-07-01T00:00:001989Potential use of lasers for penetrating keratoplasty.true1Assistant ProfessorAssistant Professortrue1Associate ProfessorAssociate Professortrue1ProfessorProfessortrue1Associate ProfessorAssociate Professortrue1ProfessorProfessorAuthorship 1066506Authorship 1064953D015352Disorders372850.735023Dry Eye SyndromesD003315Anatomy986370.678787CorneaD003228Anatomy512430.833074ConjunctivaD019573Anatomy322230.824982Epithelium, CornealAuthorship 9207026Authorship 9290854Authorship 9304911Authorship 9322989Authorship 93304910Authorship 9348985Authorship 9376453Authorship 9403797Authorship 108298529934134Zaheer M, Wang C, Bian F, Yu Z, Hernandez H, de Souza RG, Simmons KT, Schady D, Swennes AG, Pflugfelder SC, Britton RA, de Paiva CSJournal of autoimmunityProtective role of commensal bacteria in Sj?gren Syndrome. J Autoimmun. 2018 09; 93:45-56.J Autoimmun2018-06-20T00:00:002018Protective role of commensal bacteria in Sj?gren Syndrome.30010888Xiao Y, de Paiva CS, Yu Z, de Souza RG, Li DQ, Pflugfelder SCInternational immunologyGoblet cell-produced retinoic acid suppresses CD86 expression and IL-12 production in bone marrow-derived cells. Int Immunol. 2018 09 25; 30(10):457-470.Int Immunol2018-09-25T00:00:002018Goblet cell-produced retinoic acid suppresses CD86 expression and IL-12 production in bone marrow-derived cells.29958030Guimaraes de Souza R, Yu Z, Stern ME, Pflugfelder SC, de Paiva CSJournal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and TherapeuticsSuppression of Th1-Mediated Keratoconjunctivitis Sicca by Lifitegrast. J Ocul Pharmacol Ther. 2018 09; 34(7):543-549.J Ocul Pharmacol Ther2018-06-29T00:00:002018Suppression of Th1-Mediated Keratoconjunctivitis Sicca by Lifitegrast.30223431Pflugfelder SC, Bian F, Gumus K, Farley W, Stern ME, De Paiva CSInternational journal of molecular sciencesSeverity of Sj?gren's Syndrome Keratoconjunctivitis Sicca Increases with Increased Percentage of Conjunctival Antigen-Presenting Cells. Int J Mol Sci. 2018 Sep 14; 19(9).Int J Mol Sci2018-09-14T00:00:002018Severity of Sj?gren's Syndrome Keratoconjunctivitis Sicca Increases with Increased Percentage of Conjunctival Antigen-Presenting Cells.30513621Stepp MA, Pal-Ghosh S, Tadvalkar G, Williams AR, Pflugfelder SC, de Paiva CSInternational journal of molecular sciencesReduced Corneal Innervation in the CD25 Null Model of Sj?gren Syndrome. Int J Mol Sci. 2018 Nov 30; 19(12).Int J Mol Sci2018-11-30T00:00:002018Reduced Corneal Innervation in the CD25 Null Model of Sj?gren Syndrome.30515838Chen X, Deng R, Chi W, Hua X, Lu F, Bian F, Gao N, Li Z, Pflugfelder SC, de Paiva CS, Li DQAllergyIL-27 signaling deficiency develops Th17-enhanced Th2-dominant inflammation in murine allergic conjunctivitis model. Allergy. 2019 05; 74(5):910-921.Allergy2019-01-04T00:00:002019IL-27 signaling deficiency develops Th17-enhanced Th2-dominant inflammation in murine allergic conjunctivitis model.30696983Bian F, Xiao Y, Barbosa FL, de Souza RG, Hernandez H, Yu Z, Pflugfelder SC, de Paiva CSMucosal immunologyAge-associated antigen-presenting cell alterations promote dry-eye inducing Th1 cells. Mucosal Immunol. 2019 07; 12(4):897-908.Mucosal Immunol2019-01-29T00:00:002019Age-associated antigen-presenting cell alterations promote dry-eye inducing Th1 cells.30304462Stamer WD, Williams AM, Pflugfelder S, Coupland SEInvestigative ophthalmology & visual scienceAccessibility to and Quality of Human Eye Tissue for Research: A Cross-Sectional Survey of ARVO Members. Invest Ophthalmol Vis Sci. 2018 10 01; 59(12):4783-4792.Invest Ophthalmol Vis Sci2018-10-01T00:00:002018Accessibility to and Quality of Human Eye Tissue for Research: A Cross-Sectional Survey of ARVO Members.Authorship 1049601Authorship 10976552024-06-30NIHPFLUGFELDER, STEPHEN C1997-08-01Pathogenesis of Conjunctival Squamous MetaplasiaR01EY0119151990-02-28NIHPFLUGFELDER, STEPHEN CARL1989-03-01DETECTION OF EPSTEIN-BARR VIRAL DNA IN OCULAR SPECIMENSR03EY0081932011-07-31NIHPFLUGFELDER, STEPHEN CARL2009-08-01Environmentally-Induced Ocular Surface Inflammation Mimicking Sjogren's SyndromeR01EY0180901994-07-31NIHPFLUGFELDER, STEPHEN CARL1990-08-01EBV AND OCULAR PATHOLOGY IN SJOGREN'S SYNDROMER01EY008711Principal InvestigatorPrincipal InvestigatorPrincipal InvestigatorPrincipal InvestigatorD013666Anatomy291800.867813TearsPlastic SurgeryDepartment of AnesthesiologyDepartment of OphthalmologyDepartment of PediatricsDepartment of Molecular Virology & MicrobiologyAnesthesiologyMolecular Virology & MicrobiologyOphthalmologyPediatrics-Academic GeneralBaylor College of Medicine32.92040.002496781029research areas20.58540.020407129coauthor of1331.539.790960similar to11391selected publicationsERICHOLZERIC HOLZ29.70508570000000-95.401808700000003110HOLZ, ERICClinical Associate ProfessorDOUGLASKOCHDOUGLAS KOCH29.70508570000000-95.401808700000002413KOCH, DOUGLASProfessorTHOMASKOHNENTHOMAS KOHNEN29.70508570000000-95.401808700000002647KOHNEN, THOMASVisiting ProfessorDE-QUANLIDE-QUAN LI29.70508570000000-95.40180870000000283LI, DE-QUANAssociate ProfessorJANEEDMONDJANE EDMOND29.70508570000000-95.401808700000002935EDMOND, JANEAdjunct ProfessorALICEMATOBAALICE MATOBA29.70508570000000-95.401808700000002958MATOBA, ALICEAssociate ProfessorMICHELLEDALTONMICHELLE DALTON0.000000000000000.00000000000000928DALTON, MICHELLEAssistant ProfessorCINTIADE PAIVACINTIA DE PAIVA29.70508570000000-95.40180870000000305DE PAIVA, CINTIAProfessorMICHAELYENMICHAEL YEN29.70508570000000-95.40180870000000441YEN, MICHAELProfessorAuthorship 943759330502998Patel SN, Shetlar DJ, Pflugfelder SCCanadian journal of ophthalmology. Journal canadien d'ophtalmologieBilateral Candida parapsilosis infiltration of nonhealing indolent epithelial defects in a diabetic patient with neurotrophic keratopathy. Can J Ophthalmol. 2018 12; 53(6):e224-e226.Can J Ophthalmol2018-03-09T00:00:002018Bilateral Candida parapsilosis infiltration of nonhealing indolent epithelial defects in a diabetic patient with neurotrophic keratopathy.Authorship 1095477Authorship 1062072Authorship 1275788Authorship 129277323299617Su Z, Lin J, Lu F, Zhang X, Zhang L, Gandhi NB, de Paiva CS, Pflugfelder SC, Li DQMucosal immunologyPotential autocrine regulation of interleukin-33/ST2 signaling of dendritic cells in allergic inflammation. Mucosal Immunol. 2013 Sep; 6(5):921-30.Mucosal Immunol2013-01-09T00:00:002013Potential autocrine regulation of interleukin-33/ST2 signaling of dendritic cells in allergic inflammation.23499361Dimit R, Gire A, Pflugfelder SC, Bergmanson JPContact lens & anterior eye : the journal of the British Contact Lens AssociationPatient ocular conditions and clinical outcomes using a PROSE scleral device. Cont Lens Anterior Eye. 2013 Aug; 36(4):159-63.Cont Lens Anterior Eye2013-03-15T00:00:002013Patient ocular conditions and clinical outcomes using a PROSE scleral device.Authorship 9527021031350466Deng R, Chen X, Zhang Y, Bian F, Gao N, Hu J, Wang C, de Souza RG, Lu F, Pflugfelder SC, Li DQMucosal immunologyShort ragweed pollen promotes M2 macrophage polarization via TSLP/TSLPR/OX40L signaling in allergic inflammation. Mucosal Immunol. 2019 09; 12(5):1141-1149.Mucosal Immunol2019-07-26T00:00:002019Short ragweed pollen promotes M2 macrophage polarization via TSLP/TSLPR/OX40L signaling in allergic inflammation.Authorship 1120415Authorship 955486231517988de Paiva CS, Pflugfelder SC, Ng SM, Akpek EKThe Cochrane database of systematic reviewsTopical cyclosporine A therapy for dry eye syndrome. Cochrane Database Syst Rev. 2019 09 13; 9:CD010051.Cochrane Database Syst Rev2019-09-13T00:00:002019Topical cyclosporine A therapy for dry eye syndrome.Authorship 956468131585826Pflugfelder SC, Massaro-Giordano M, Perez VL, Hamrah P, Deng SX, Espandar L, Foster CS, Affeldt J, Seedor JA, Afshari NA, Chao W, Allegretti M, Mantelli F, Dana ROphthalmologyTopical Recombinant Human Nerve Growth Factor (Cenegermin) for Neurotrophic Keratopathy: A Multicenter Randomized Vehicle-Controlled Pivotal Trial. Ophthalmology. 2020 01; 127(1):14-26.Ophthalmology2019-08-26T00:00:002019Topical Recombinant Human Nerve Growth Factor (Cenegermin) for Neurotrophic Keratopathy: A Multicenter Randomized Vehicle-Controlled Pivotal Trial.Authorship 957331531618426Wang C, Schaefer L, Bian F, Yu Z, Pflugfelder SC, Britton RA, de Paiva CSInvestigative ophthalmology & visual scienceDysbiosis Modulates Ocular Surface Inflammatory Response to Liposaccharide. Invest Ophthalmol Vis Sci. 2019 10 01; 60(13):4224-4233.Invest Ophthalmol Vis Sci2019-10-01T00:00:002019Dysbiosis Modulates Ocular Surface Inflammatory Response to Liposaccharide.Authorship 957751431644955Trujillo-Vargas CM, Schaefer L, Alam J, Pflugfelder SC, Britton RA, de Paiva CSThe ocular surfaceThe gut-eye-lacrimal gland-microbiome axis in Sj?gren Syndrome. Ocul Surf. 2020 04; 18(2):335-344.Ocul Surf2019-10-20T00:00:002019The gut-eye-lacrimal gland-microbiome axis in Sj?gren Syndrome.Authorship 958247231675394Hsu JI, Pflugfelder SC, Kim SJCutisOcular complications of atopic dermatitis. Cutis. 2019 Sep; 104(3):189-193.Cutis2019-09-01T00:00:002019Ocular complications of atopic dermatitis.true1ProfessorProfessorAuthorship 1130152Authorship 976000331953222Alam J, de Paiva CS, Pflugfelder SCThe ocular surfaceImmune - Goblet cell interaction in the conjunctiva. Ocul Surf. 2020 04; 18(2):326-334.Ocul Surf2020-01-14T00:00:002020Immune - Goblet cell interaction in the conjunctiva.Authorship 976163231963817de Paiva CS, Pflugfelder SCInternational journal of molecular sciencesMechanisms of Disease in Sj?gren Syndrome-New Developments and Directions. Int J Mol Sci. 2020 Jan 19; 21(2).Int J Mol Sci2020-01-19T00:00:002020Mechanisms of Disease in Sj?gren Syndrome-New Developments and Directions.Authorship 1143312Authorship 1098886Authorship 978090832076085Khimani KS, Go JA, De Souza RG, Mitchell T, Yu Z, de Paiva CS, Saumur M, Pflugfelder SCScientific reportsRegional Comparison of Goblet Cell Number and Area in Exposed and Covered Dry Eyes and Their Correlation with Tear MUC5AC. Sci Rep. 2020 02 19; 10(1):2933.Sci Rep2020-02-19T00:00:002020Regional Comparison of Goblet Cell Number and Area in Exposed and Covered Dry Eyes and Their Correlation with Tear MUC5AC.Authorship 1105185true1Clinical Associate ProfessorClinical Associate Professortrue1Adjunct Assistant ProfessorAdjunct Assistant Professortrue1Visiting ProfessorVisiting ProfessorAuthorship 9884931032358573Hu J, Gao N, Zhang Y, Chen X, Li J, Bian F, Chi W, Liu Z, de Paiva CS, Pflugfelder SC, Li DQMucosal immunologyIL-33/ST2/IL-9/IL-9R signaling disrupts ocular surface barrier in allergic inflammation. Mucosal Immunol. 2020 11; 13(6):919-930.Mucosal Immunol2020-05-01T00:00:002020IL-33/ST2/IL-9/IL-9R signaling disrupts ocular surface barrier in allergic inflammation.Authorship 989956432439390Utine CA, Li G, Asbell P, Pflugfelder S, Akpek EThe ocular surfaceOcular surface disease associated with dupilumab treatment for atopic diseases. Ocul Surf. 2021 01; 19:151-156.Ocul Surf2020-05-18T00:00:002020Ocular surface disease associated with dupilumab treatment for atopic diseases.Authorship 992188132561483Pflugfelder SC, Stern MEExperimental eye researchBiological functions of tear film. Exp Eye Res. 2020 08; 197:108115.Exp Eye Res2020-06-16T00:00:002020Biological functions of tear film.Authorship 993187132616838Pflugfelder SC, de Paiva CSMucosal immunologyGoblet cells promote tolerance induction in the conjunctiva. Mucosal Immunol. 2020 09; 13(5):717-718.Mucosal Immunol2020-07-02T00:00:002020Goblet cells promote tolerance induction in the conjunctiva.Authorship 995562632721249Alam J, de Souza RG, Yu Z, Stern ME, de Paiva CS, Pflugfelder SCJournal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and TherapeuticsCalcineurin Inhibitor Voclosporin Preserves Corneal Barrier and Conjunctival Goblet Cells in Experimental Dry Eye. J Ocul Pharmacol Ther. 2020 11; 36(9):679-685.J Ocul Pharmacol Ther2020-07-23T00:00:002020Calcineurin Inhibitor Voclosporin Preserves Corneal Barrier and Conjunctival Goblet Cells in Experimental Dry Eye.Authorship 996872932785678Liu Z, Chen D, Chen X, Bian F, Qin W, Gao N, Xiao Y, Li J, Pflugfelder SC, Li DQInvestigative ophthalmology & visual scienceTrehalose Induces Autophagy Against Inflammation by Activating TFEB Signaling Pathway in Human Corneal Epithelial Cells Exposed to Hyperosmotic Stress. Invest Ophthalmol Vis Sci. 2020 08 03; 61(10):26.Invest Ophthalmol Vis Sci2020-08-03T00:00:002020Trehalose Induces Autophagy Against Inflammation by Activating TFEB Signaling Pathway in Human Corneal Epithelial Cells Exposed to Hyperosmotic Stress.Authorship 1173393Authorship 999499632923645Ganugula R, Arora M, Lepiz MA, Niu Y, Mallick BK, Pflugfelder SC, Scott EM, Kumar MNVRScience advancesSystemic anti-inflammatory therapy aided by double-headed nanoparticles in a canine model of acute intraocular inflammation. Sci Adv. 2020 08; 6(35):eabb7878.Sci Adv2020-08-26T00:00:002020Systemic anti-inflammatory therapy aided by double-headed nanoparticles in a canine model of acute intraocular inflammation.Authorship 1126595Authorship 1190955Authorship 10026061Authorship 1002624333038387Pflugfelder SC, Stern MEExperimental eye researchThe cornea in keratoconjunctivitis sicca. Exp Eye Res. 2020 12; 201:108295.Exp Eye Res2020-10-07T00:00:002020The cornea in keratoconjunctivitis sicca.33039458Perez VL, Stern ME, Pflugfelder SCExperimental eye researchInflammatory basis for dry eye disease flares. Exp Eye Res. 2020 12; 201:108294.Exp Eye Res2020-10-08T00:00:002020Inflammatory basis for dry eye disease flares.Authorship 10033715Authorship 119332133094195Kamal SM, Riccobono K, Kwok A, Edmond JC, Pflugfelder SCAmerican journal of ophthalmology case reportsUnilateral pediatric neurotrophic keratitis due to congenital left trigeminal nerve aplasia with PROSE (prosthetic replacement of the ocular surface ecosystem) treatment. Am J Ophthalmol Case Rep. 2020 Dec; 20:100854.Am J Ophthalmol Case Rep2020-08-03T00:00:002020Unilateral pediatric neurotrophic keratitis due to congenital left trigeminal nerve aplasia with PROSE (prosthetic replacement of the ocular surface ecosystem) treatment.Authorship 10061286Authorship 1006141733255287Trujillo-Vargas CM, Kutlehria S, Hernandez H, de Souza RG, Lee A, Yu Z, Pflugfelder SC, Singh M, de Paiva CSInternational journal of molecular sciencesRapamycin Eyedrops Increased CD4+Foxp3+ Cells and Prevented Goblet Cell Loss in the Aged Ocular Surface. Int J Mol Sci. 2020 Nov 24; 21(23).Int J Mol Sci2020-11-24T00:00:002020Rapamycin Eyedrops Increased CD4+Foxp3+ Cells and Prevented Goblet Cell Loss in the Aged Ocular Surface.33255884Liu Z, Chen D, Chen X, Bian F, Gao N, Li J, Pflugfelder SC, Li DQInternational journal of molecular sciencesAutophagy Activation Protects Ocular Surface from Inflammation in a Dry Eye Model In Vitro. 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Ocul Surf. 2021 04; 20:20-32.Ocul Surf2021-01-01T00:00:002021Single-cell transcriptomics identifies limbal stem cell population and cell types mapping its differentiation trajectory in limbal basal epithelium of human cornea.Authorship 1009957433499199Alam J, Yu Z, de Paiva CS, Pflugfelder SCInternational journal of molecular sciencesRetinoid Regulation of Ocular Surface Innate Inflammation. Int J Mol Sci. 2021 Jan 22; 22(3).Int J Mol Sci2021-01-22T00:00:002021Retinoid Regulation of Ocular Surface Innate Inflammation.Authorship 1011169233571473Gumus K, Pflugfelder SCAmerican journal of ophthalmologyConjunctivochalasis and Tear Osmolarity Are Associated With Reduced Conjunctival Epithelial Thickness in Dry Eye. 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BMC Ophthalmol. 2021 Sep 08; 21(1):327.BMC Ophthalmol2021-09-08T00:00:002021Expert consensus on the identification, diagnosis, and treatment of neurotrophic keratopathy.Authorship 1030040734537416Wang M, Yennam S, McMillin J, Chen HH, de la Sen-Corcuera B, Hemmati R, Pflugfelder SThe ocular surfaceCombined therapy of ocular surface disease with plasma rich in growth factors and scleral contact lenses. Ocul Surf. 2022 01; 23:162-168.Ocul Surf2021-09-17T00:00:002021Combined therapy of ocular surface disease with plasma rich in growth factors and scleral contact lenses.Authorship 1187054Authorship 10384485Authorship 10417254Authorship 1041797735296712Schaefer L, Hernandez H, Coats RA, Yu Z, Pflugfelder SC, Britton RA, de Paiva CSScientific reportsGut-derived butyrate suppresses ocular surface inflammation. Sci Rep. 2022 03 16; 12(1):4512.Sci Rep2022-03-16T00:00:002022Gut-derived butyrate suppresses ocular surface inflammation.35361907Alam J, Yazdanpanah G, Ratnapriya R, Borcherding N, de Paiva CS, Li D, Pflugfelder SCMucosal immunologySingle-cell transcriptional profiling of murine conjunctival immune cells reveals distinct populations expressing homeostatic and regulatory genes. Mucosal Immunol. 2022 04; 15(4):620-628.Mucosal Immunol2022-03-31T00:00:002022Single-cell transcriptional profiling of murine conjunctival immune cells reveals distinct populations expressing homeostatic and regulatory genes.35355610Schaefer L, Trujillo-Vargas CM, Midani FS, Pflugfelder SC, Britton RA, de Paiva CSFrontiers in medicineGut Microbiota From Sj?gren syndrome Patients Causes Decreased T Regulatory Cells in the Lymphoid Organs and Desiccation-Induced Corneal Barrier Disruption in Mice. Front Med (Lausanne). 2022; 9:852918.Front Med (Lausanne)2022-03-09T00:00:002022Gut Microbiota From Sj?gren syndrome Patients Causes Decreased T Regulatory Cells in the Lymphoid Organs and Desiccation-Induced Corneal Barrier Disruption in Mice.Authorship 1186964Authorship 149111Authorship 10436609Authorship 1044287535402439Alam J, Yazdanpanah G, Ratnapriya R, Borcherding N, de Paiva CS, Li D, Guimaraes de Souza R, Yu Z, Pflugfelder SCFrontiers in medicineIL-17 Producing Lymphocytes Cause Dry Eye and Corneal Disease With Aging in RXRa Mutant Mouse. Front Med (Lausanne). 2022; 9:849990.Front Med (Lausanne)2022-03-23T00:00:002022IL-17 Producing Lymphocytes Cause Dry Eye and Corneal Disease With Aging in RXRa Mutant Mouse.35449441Schaefer L, Hernandez H, Coats RA, Yu Z, Pflugfelder SC, Britton RA, de Paiva CSScientific reportsAuthor Correction: Gut-derived butyrate suppresses ocular surface inflammation. Sci Rep. 2022 Apr 21; 12(1):6581.Sci Rep2022-04-21T00:00:002022Author Correction: Gut-derived butyrate suppresses ocular surface inflammation.Authorship 1365548Authorship 1369601Authorship 1382814Authorship 1383676Authorship 1044835735489588Soifer M, Tovar A, Wang M, Mousa HM, Yennam S, Sabater AL, Pflugfelder SC, Perez VLThe ocular surfaceA multicenter report of the use of plasma rich in growth factors (PRGF) for the treatment of patients with ocular surface diseases in North America. Ocul Surf. 2022 07; 25:40-48.Ocul Surf2022-04-27T00:00:002022A multicenter report of the use of plasma rich in growth factors (PRGF) for the treatment of patients with ocular surface diseases in North America.23983225Gandhi NB, Su Z, Zhang X, Volpe EA, Pelegrino FS, Rahman SA, Li DQ, Pflugfelder SC, de Paiva CSJournal of leukocyte biologyDendritic cell-derived thrombospondin-1 is critical for the generation of the ocular surface Th17 response to desiccating stress. 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Ocul Surf. 2022 10; 26:200-208.Ocul Surf2022-09-18T00:00:002022Multicenter prospective validation study for international chronic ocular graft-versus-host disease consensus diagnostic criteria.Authorship 1223087Authorship 1224512Authorship 1063979436796014Perez VL, Mah FS, Willcox M, Pflugfelder SJournal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and TherapeuticsAnti-Inflammatories in the Treatment of Dry Eye Disease: A Review. J Ocul Pharmacol Ther. 2023 03; 39(2):89-101.J Ocul Pharmacol Ther2023-02-16T00:00:002023Anti-Inflammatories in the Treatment of Dry Eye Disease: A Review.Authorship 1065194836875531Farid M, Ayres BD, Donnenfeld E, Gaddie IB, Gupta PK, Holland E, Lindstrom R, Pflugfelder SC, Karpecki PM, Nichols KK, Starr CE, Yeu EClinical ophthalmology (Auckland, N.Z.)Delphi Panel Consensus Regarding Current Clinical Practice Management Options for Demodex blepharitis. Clin Ophthalmol. 2023; 17:667-679.Clin Ophthalmol2023-02-27T00:00:002023Delphi Panel Consensus Regarding Current Clinical Practice Management Options for Demodex blepharitis.Authorship 1065908436913382Kikukawa Y, Tanaka S, Kosugi T, Pflugfelder SCPloS oneNon-invasive and objective tear film breakup detection on interference color images using convolutional neural networks. PLoS One. 2023; 18(3):e0282973.PLoS One2023-03-13T00:00:002023Non-invasive and objective tear film breakup detection on interference color images using convolutional neural networks.Authorship 179424Authorship 10661451036964261Ayres BD, Donnenfeld E, Farid M, Gaddie IB, Gupta PK, Holland E, Karpecki PM, Lindstrom R, Nichols KK, Pflugfelder SC, Starr CE, Yeu EEye (London, England)Clinical diagnosis and management of Demodex blepharitis: the Demodex Expert Panel on Treatment and Eyelid Health (DEPTH). Eye (Lond). 2023 Oct; 37(15):3249-3255.Eye (Lond)2023-03-24T00:00:002023Clinical diagnosis and management of Demodex blepharitis: the Demodex Expert Panel on Treatment and Eyelid Health (DEPTH).Authorship 1066923536982810de Souza RG, Huang D, Prahl S, Nakhleh L, Pflugfelder SCInternational journal of molecular sciencesComparison of Efficacy and Inflammatory Response to Thermoconjunctivoplasty Performed with Cautery or Pulsed 1460 nm Laser. Int J Mol Sci. 2023 Mar 17; 24(6).Int J Mol Sci2023-03-17T00:00:002023Comparison of Efficacy and Inflammatory Response to Thermoconjunctivoplasty Performed with Cautery or Pulsed 1460 nm Laser.Authorship 1067738537036417Yu Z, Yazdanpanah G, Alam J, de Paiva CS, Pflugfelder SInvestigative ophthalmology & visual scienceInduction of Innate Inflammatory Pathways in the Corneal Epithelium in the Desiccating Stress Dry Eye Model. Invest Ophthalmol Vis Sci. 2023 04 03; 64(4):8.Invest Ophthalmol Vis Sci2023-04-03T00:00:002023Induction of Innate Inflammatory Pathways in the Corneal Epithelium in the Desiccating Stress Dry Eye Model.Authorship 183731Authorship 10722175Authorship 1072608337310735Yoon SP, Yu Z, Pflugfelder SC, de Paiva CSTranslational vision science & technologyDifferentially Expressed Tear Proteins in Sj?gren's Syndrome Keratoconjunctivitis Sicca. Transl Vis Sci Technol. 2023 06 01; 12(6):8.Transl Vis Sci Technol2023-06-01T00:00:002023Differentially Expressed Tear Proteins in Sj?gren's Syndrome Keratoconjunctivitis Sicca.37257694Oganov A, Yazdanpanah G, Jabbehdari S, Belamkar A, Pflugfelder SThe ocular surfaceDry eye disease and blinking behaviors: A narrative review of methodologies for measuring blink dynamics and inducing blink response. Ocul Surf. 2023 Jul; 29:166-174.Ocul Surf2023-05-29T00:00:002023Dry eye disease and blinking behaviors: A narrative review of methodologies for measuring blink dynamics and inducing blink response.Authorship 1074961337458425Ammassam Veettil R, Li W, Pflugfelder SC, Koch DDJournal of visualized experiments : JoVEA Mouse Model for Corneal Neovascularization by Alkali Burn. J Vis Exp. 2023 06 30; (196).J Vis Exp2023-06-30T00:00:002023A Mouse Model for Corneal Neovascularization by Alkali Burn.Authorship 12764Authorship 14736Authorship 202672Authorship 148134Authorship 2083182026-06-30NIHDE PAIVA, CINTIA S.2023-07-01Multi-method investigation and characterization of the ocular microbiomeU24EY035067Co-Principal Investigatortrue1ProfessorProfessorAuthorship 177853Authorship 1781711Authorship 186197Authorship 230571Authorship 23166Authorship 10891748Authorship 1089391938395195Stern ME, Theofilopoulos AN, Steven P, Niederkorn JY, Fox R, Calonge M, Scheid C, Pflugfelder SCThe ocular surfaceImmunologic basis for development of keratoconjunctivitis sicca in systemic autoimmune diseases: Role of innate immune sensors. Ocul Surf. 2024 Feb 22; 32:130-138.Ocul Surf2024-02-22T00:00:002024Immunologic basis for development of keratoconjunctivitis sicca in systemic autoimmune diseases: Role of innate immune sensors.38399289Chen X, Lin N, Li JM, Liu H, Abu-Romman A, Yaman E, Bian F, de Paiva CS, Pflugfelder SC, Li DQPharmaceuticsEctoine, from a Natural Bacteria Protectant to a New Treatment of Dry Eye Disease. Pharmaceutics. 2024 Feb 05; 16(2).Pharmaceutics2024-02-05T00:00:002024Ectoine, from a Natural Bacteria Protectant to a New Treatment of Dry Eye Disease.Authorship 235002Authorship 235184Authorship 1090735938490477Li JM, Lin N, Zhang Y, Chen X, Liu Z, Lu R, Bian F, Liu H, Pflugfelder SC, Li DQThe ocular surfaceEctoine protects corneal epithelial survival and barrier from hyperosmotic stress by promoting anti-inflammatory cytokine IL-37. Ocul Surf. 2024 Mar 13.Ocul Surf2024-03-13T00:00:002024Ectoine protects corneal epithelial survival and barrier from hyperosmotic stress by promoting anti-inflammatory cytokine IL-37.true1ProfessorProfessorAuthorship 20084Authorship 183478Authorship 217984Authorship 224491Authorship 23244Authorship 20431Authorship 218126Authorship 263204Authorship 265954Authorship 34592Authorship 267723Authorship 369242Authorship 369861Authorship 392413Authorship 282581Authorship 410605Authorship 411924Authorship 295587Authorship 285712Authorship 434171Authorship 450022Authorship 306203Authorship 456315Authorship 311573Authorship 326833Authorship 14094110Authorship 1412664Authorship 1416944Authorship 1418556Authorship 1421967Authorship 1423366Authorship 1423751Authorship 142488824022789Zhang X, Schaumburg CS, Coursey TG, Siemasko KF, Volpe EA, Gandhi NB, Li DQ, Niederkorn JY, Stern ME, Pflugfelder SC, de Paiva CSMucosal immunologyCD8? cells regulate the T helper-17 response in an experimental murine model of Sj?gren syndrome. Mucosal Immunol. 2014 Mar; 7(2):417-27.Mucosal Immunol2013-09-11T00:00:002013CD8? cells regulate the T helper-17 response in an experimental murine model of Sj?gren syndrome.24215436Villani E, Baudouin C, Efron N, Hamrah P, Kojima T, Patel SV, Pflugfelder SC, Zhivov A, Dogru MCurrent eye researchIn vivo confocal microscopy of the ocular surface: from bench to bedside. Curr Eye Res. 2014 Mar; 39(3):213-31.Curr Eye Res2013-11-11T00:00:002013In vivo confocal microscopy of the ocular surface: from bench to bedside.24315297Tung CI, Perin AF, Gumus K, Pflugfelder SCAmerican journal of ophthalmologyTear meniscus dimensions in tear dysfunction and their correlation with clinical parameters. Am J Ophthalmol. 2014 Feb; 157(2):301-310.e1.Am J Ophthalmol2013-09-28T00:00:002013Tear meniscus dimensions in tear dysfunction and their correlation with clinical parameters.24342754Chen JJ, Applebaum DS, Sun GS, Pflugfelder SCJournal of the American Academy of DermatologyAtopic keratoconjunctivitis: A review. J Am Acad Dermatol. 2014 Mar; 70(3):569-75.J Am Acad Dermatol2013-12-15T00:00:002013Atopic keratoconjunctivitis: A review.24389165McClellan AJ, Volpe EA, Zhang X, Darlington GJ, Li DQ, Pflugfelder SC, de Paiva CSThe American journal of pathologyOcular surface disease and dacryoadenitis in aging C57BL/6 mice. Am J Pathol. 2014 Mar; 184(3):631-43.Am J Pathol2014-01-03T00:00:002014Ocular surface disease and dacryoadenitis in aging C57BL/6 mice.24439047Suhalim JL, Parfitt GJ, Xie Y, De Paiva CS, De Pavia CS, Pflugfelder SC, Shah TN, Potma EO, Brown DJ, Jester JVThe ocular surfaceEffect of desiccating stress on mouse meibomian gland function. 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Expert Rev Clin Immunol. 2014 Apr; 10(4):425-7.Expert Rev Clin Immunol2014-02-25T00:00:002014What causes dryness in Sj?gren's syndrome patients and how can it be targeted?Authorship 335283Authorship 350781Authorship 505261Authorship 352252Authorship 531835Authorship 362102Authorship 379831Authorship 370673Authorship 549045Authorship 393235Authorship 386473Authorship 38655Authorship 388386Authorship 392812Authorship 398697Authorship 402537Authorship 420194Authorship 1459772Authorship 145990524631478Foulks GN, Pflugfelder SCAmerican journal of ophthalmologyNew testing options for diagnosing and grading dry eye disease. Am J Ophthalmol. 2014 Jun; 157(6):1122-9.Am J Ophthalmol2014-03-12T00:00:002014New testing options for diagnosing and grading dry eye disease.24662332Hua X, Yuan X, Tang X, Li Z, Pflugfelder SC, Li DQOphthalmic researchHuman corneal epithelial cells produce antimicrobial peptides LL-37 and ?-defensins in response to heat-killed Candida albicans. Ophthalmic Res. 2014; 51(4):179-86.Ophthalmic Res2014-03-18T00:00:002014Human corneal epithelial cells produce antimicrobial peptides LL-37 and ?-defensins in response to heat-killed Candida albicans.Authorship 420917Authorship 452721Authorship 455962Authorship 64464Authorship 477791Authorship 478274Authorship 4869210Authorship 497338Authorship 6978912Authorship 70056Authorship 499156Authorship 507724Authorship 148252523116218Pelegrino FS, Volpe EA, Gandhi NB, Li DQ, Pflugfelder SC, de Paiva CSArthritis research & therapyDeletion of interferon-? delays onset and severity of dacryoadenitis in CD25KO mice. Arthritis Res Ther. 2012 Nov 01; 14(6):R234.Arthritis Res Ther2012-11-01T00:00:002012Deletion of interferon-? delays onset and severity of dacryoadenitis in CD25KO mice.Authorship 521406Authorship 528873Authorship 529923Authorship 743692Authorship 744223Authorship 538444Authorship 533126Authorship 541614Authorship 548965Authorship 544217Authorship 547467Authorship 561001Authorship 568056Authorship 572073Authorship 582013Authorship 583532Authorship 833926Authorship 834226Authorship 593610Authorship 843101Authorship 843618Authorship 844303Authorship 846224Authorship 604656Authorship 1508231Authorship 150829925075545Pflugfelder SC, Stern MEExpert review of clinical immunologyMucosal environmental sensors in the pathogenesis of dry eye. Expert Rev Clin Immunol. 2014 Sep; 10(9):1137-40.Expert Rev Clin Immunol2014-07-30T00:00:002014Mucosal environmental sensors in the pathogenesis of dry eye.25083776Sheppard JD, Donnenfeld ED, Holland EJ, Slonim CB, Solomon R, Solomon KD, McDonald MB, Perry HD, Lane SS, Pflugfelder SC, Samudre SSEye & contact lensEffect of loteprednol etabonate 0.5% on initiation of dry eye treatment with topical cyclosporine 0.05%. Eye Contact Lens. 2014 Sep; 40(5):289-96.Eye Contact Lens2014-09-01T00:00:002014Effect of loteprednol etabonate 0.5% on initiation of dry eye treatment with topical cyclosporine 0.05%.Authorship 617186Authorship 8636811Authorship 642232Authorship 90281Authorship 652298Authorship 911875Authorship 915722Authorship 917212Authorship 9434011Authorship 664884Authorship 68292Authorship 954785Authorship 685486Authorship 700353Authorship 983837Authorship 988631Authorship 68696Authorship 722817Authorship 722823Authorship 714541Authorship 730807Authorship 735834Authorship 724703Authorship 730435Authorship 751253Authorship 7768613Authorship 1549151Authorship 1549174Authorship 1555046