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STEPHEN PFLUGFELDER to Mice, Inbred C57BL

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This is a "connection" page, showing publications STEPHEN PFLUGFELDER has written about Mice, Inbred C57BL.
STEPHEN PFLUGFELDER
Connection Strength
3.239
Mice, Inbred C57BL
  1. Changes in conjunctival mononuclear phagocytes and suppressive activity of regulatory macrophages in desiccation induced dry eye. Ocul Surf. 2024 Oct; 34:348-362.
    View in: PubMed
    Score: 0.480
  2. Mouse Corneal Immune Cell Heterogeneity Revealed by Single-Cell RNA Sequencing. Invest Ophthalmol Vis Sci. 2024 Oct 01; 65(12):29.
    View in: PubMed
    Score: 0.120
  3. Ectoine Enhances Mucin Production Via Restoring IL-13/IFN-? Balance in a Murine Dry Eye Model. Invest Ophthalmol Vis Sci. 2024 Jun 03; 65(6):39.
    View in: PubMed
    Score: 0.118
  4. Induction of Innate Inflammatory Pathways in the Corneal Epithelium in the Desiccating Stress Dry Eye Model. Invest Ophthalmol Vis Sci. 2023 04 03; 64(4):8.
    View in: PubMed
    Score: 0.108
  5. Comparison of Efficacy and Inflammatory Response to Thermoconjunctivoplasty Performed with Cautery or Pulsed 1460 nm Laser. Int J Mol Sci. 2023 Mar 17; 24(6).
    View in: PubMed
    Score: 0.108
  6. Desiccation Induced Conjunctival Monocyte Recruitment and Activation - Implications for Keratoconjunctivitis. Front Immunol. 2021; 12:701415.
    View in: PubMed
    Score: 0.096
  7. Retinoid Regulation of Ocular Surface Innate Inflammation. Int J Mol Sci. 2021 Jan 22; 22(3).
    View in: PubMed
    Score: 0.093
  8. Calcineurin Inhibitor Voclosporin Preserves Corneal Barrier and Conjunctival Goblet Cells in Experimental Dry Eye. J Ocul Pharmacol Ther. 2020 11; 36(9):679-685.
    View in: PubMed
    Score: 0.090
  9. Goblet cell-produced retinoic acid suppresses CD86 expression and IL-12 production in bone marrow-derived cells. Int Immunol. 2018 09 25; 30(10):457-470.
    View in: PubMed
    Score: 0.079
  10. Goblet cell loss abrogates ocular surface immune tolerance. JCI Insight. 2018 02 08; 3(3).
    View in: PubMed
    Score: 0.076
  11. Goblet Cells Contribute to Ocular Surface Immune Tolerance-Implications for Dry Eye Disease. Int J Mol Sci. 2017 May 05; 18(5).
    View in: PubMed
    Score: 0.072
  12. Altered Mucosal Microbiome Diversity and Disease Severity in Sj?gren Syndrome. Sci Rep. 2016 Apr 18; 6:23561.
    View in: PubMed
    Score: 0.067
  13. Interferon-?-Induced Unfolded Protein Response in Conjunctival Goblet Cells as a Cause of Mucin Deficiency in Sj?gren Syndrome. Am J Pathol. 2016 06; 186(6):1547-58.
    View in: PubMed
    Score: 0.067
  14. IL-13 Stimulates Proliferation and Expression of Mucin and Immunomodulatory Genes in Cultured Conjunctival Goblet Cells. Invest Ophthalmol Vis Sci. 2015 Jul; 56(8):4186-97.
    View in: PubMed
    Score: 0.063
  15. Age-Related Conjunctival Disease in the C57BL/6.NOD-Aec1Aec2 Mouse Model of Sj?gren Syndrome Develops Independent of Lacrimal Dysfunction. Invest Ophthalmol Vis Sci. 2015 Apr; 56(4):2224-33.
    View in: PubMed
    Score: 0.062
  16. Macrophage Phenotype in the Ocular Surface of Experimental Murine Dry Eye Disease. Arch Immunol Ther Exp (Warsz). 2015 Aug; 63(4):299-304.
    View in: PubMed
    Score: 0.062
  17. Topical interferon-gamma neutralization prevents conjunctival goblet cell loss in experimental murine dry eye. Exp Eye Res. 2014 Jan; 118:117-24.
    View in: PubMed
    Score: 0.057
  18. Autoantibodies contribute to the immunopathogenesis of experimental dry eye disease. Invest Ophthalmol Vis Sci. 2012 Apr 24; 53(4):2062-75.
    View in: PubMed
    Score: 0.051
  19. Desiccating stress induces CD4+ T-cell-mediated Sj?gren's syndrome-like corneal epithelial apoptosis via activation of the extrinsic apoptotic pathway by interferon-?. Am J Pathol. 2011 Oct; 179(4):1807-14.
    View in: PubMed
    Score: 0.048
  20. Interferon-? exacerbates dry eye-induced apoptosis in conjunctiva through dual apoptotic pathways. Invest Ophthalmol Vis Sci. 2011 Aug 09; 52(9):6279-85.
    View in: PubMed
    Score: 0.048
  21. Entrapment of conjunctival goblet cells by desiccation-induced cornification. Invest Ophthalmol Vis Sci. 2011 Jun 01; 52(6):3492-9.
    View in: PubMed
    Score: 0.048
  22. Pharmacological cholinergic blockade stimulates inflammatory cytokine production and lymphocytic infiltration in the mouse lacrimal gland. Invest Ophthalmol Vis Sci. 2011 May 16; 52(6):3221-7.
    View in: PubMed
    Score: 0.048
  23. Homeostatic control of conjunctival mucosal goblet cells by NKT-derived IL-13. Mucosal Immunol. 2011 Jul; 4(4):397-408.
    View in: PubMed
    Score: 0.046
  24. Desiccating stress promotion of Th17 differentiation by ocular surface tissues through a dendritic cell-mediated pathway. Invest Ophthalmol Vis Sci. 2010 Jun; 51(6):3083-91.
    View in: PubMed
    Score: 0.044
  25. Age-related T-cell cytokine profile parallels corneal disease severity in Sjogren's syndrome-like keratoconjunctivitis sicca in CD25KO mice. Rheumatology (Oxford). 2010 Feb; 49(2):246-58.
    View in: PubMed
    Score: 0.043
  26. Essential role for c-Jun N-terminal kinase 2 in corneal epithelial response to desiccating stress. Arch Ophthalmol. 2009 Dec; 127(12):1625-31.
    View in: PubMed
    Score: 0.043
  27. Spontaneous T cell mediated keratoconjunctivitis in Aire-deficient mice. Br J Ophthalmol. 2009 Sep; 93(9):1260-4.
    View in: PubMed
    Score: 0.041
  28. IL-17 disrupts corneal barrier following desiccating stress. Mucosal Immunol. 2009 May; 2(3):243-53.
    View in: PubMed
    Score: 0.041
  29. Desiccating stress decreases apical corneal epithelial cell size--modulation by the metalloproteinase inhibitor doxycycline. Cornea. 2008 Sep; 27(8):935-40.
    View in: PubMed
    Score: 0.039
  30. Interleukin-1 receptor-1-deficient mice show attenuated production of ocular surface inflammatory cytokines in experimental dry eye. Cornea. 2008 Aug; 27(7):811-7.
    View in: PubMed
    Score: 0.039
  31. Dry eye-induced conjunctival epithelial squamous metaplasia is modulated by interferon-gamma. Invest Ophthalmol Vis Sci. 2007 Jun; 48(6):2553-60.
    View in: PubMed
    Score: 0.036
  32. Expression of Th-1 chemokines and chemokine receptors on the ocular surface of C57BL/6 mice: effects of desiccating stress. Invest Ophthalmol Vis Sci. 2007 Jun; 48(6):2561-9.
    View in: PubMed
    Score: 0.036
  33. Strain-related cytokine profiles on the murine ocular surface in response to desiccating stress. Cornea. 2007 Jun; 26(5):579-84.
    View in: PubMed
    Score: 0.036
  34. Effect of topical ophthalmic epinastine and olopatadine on tear volume in mice. Eye Contact Lens. 2006 Dec; 32(6):272-6.
    View in: PubMed
    Score: 0.035
  35. Desiccating stress stimulates expression of matrix metalloproteinases by the corneal epithelium. Invest Ophthalmol Vis Sci. 2006 Aug; 47(8):3293-302.
    View in: PubMed
    Score: 0.034
  36. Apical corneal barrier disruption in experimental murine dry eye is abrogated by methylprednisolone and doxycycline. Invest Ophthalmol Vis Sci. 2006 Jul; 47(7):2847-56.
    View in: PubMed
    Score: 0.034
  37. Corticosteroid and doxycycline suppress MMP-9 and inflammatory cytokine expression, MAPK activation in the corneal epithelium in experimental dry eye. Exp Eye Res. 2006 Sep; 83(3):526-35.
    View in: PubMed
    Score: 0.034
  38. Effect of experimental dry eye on tear sodium concentration in the mouse. Eye Contact Lens. 2005 Jul; 31(4):175-8.
    View in: PubMed
    Score: 0.032
  39. Destructive and protective effects and therapeutic targets of IL-36 family cytokines in dry eye disease. Ocul Surf. 2025 Apr; 36:83-93.
    View in: PubMed
    Score: 0.031
  40. Topical cyclosporine inhibits conjunctival epithelial apoptosis in experimental murine keratoconjunctivitis sicca. Cornea. 2005 Jan; 24(1):80-5.
    View in: PubMed
    Score: 0.031
  41. Dysbiosis Modulates Ocular Surface Inflammatory Response to Liposaccharide. Invest Ophthalmol Vis Sci. 2019 10 01; 60(13):4224-4233.
    View in: PubMed
    Score: 0.021
  42. Suppression of Th1-Mediated Keratoconjunctivitis Sicca by Lifitegrast. J Ocul Pharmacol Ther. 2018 09; 34(7):543-549.
    View in: PubMed
    Score: 0.019
  43. Protective role of commensal bacteria in Sj?gren Syndrome. J Autoimmun. 2018 09; 93:45-56.
    View in: PubMed
    Score: 0.019
  44. Sj?gren-Like Lacrimal Keratoconjunctivitis in Germ-Free Mice. Int J Mol Sci. 2018 Feb 13; 19(2).
    View in: PubMed
    Score: 0.019
  45. Reduced intraepithelial corneal nerve density and sensitivity accompany desiccating stress and aging in C57BL/6 mice. Exp Eye Res. 2018 04; 169:91-98.
    View in: PubMed
    Score: 0.019
  46. Inhibition of NLRP3 Inflammasome Pathway by Butyrate Improves Corneal Wound Healing in Corneal Alkali Burn. Int J Mol Sci. 2017 Mar 05; 18(3).
    View in: PubMed
    Score: 0.018
  47. Mitochondrial DNA oxidation induces imbalanced activity of NLRP3/NLRP6 inflammasomes by activation of caspase-8 and BRCC36 in dry eye. J Autoimmun. 2017 Jun; 80:65-76.
    View in: PubMed
    Score: 0.018
  48. Age-related spontaneous lacrimal keratoconjunctivitis is accompanied by dysfunctional T regulatory cells. Mucosal Immunol. 2017 05; 10(3):743-756.
    View in: PubMed
    Score: 0.017
  49. Interferon-gamma deficiency protects against aging-related goblet cell loss. Oncotarget. 2016 10 04; 7(40):64605-64614.
    View in: PubMed
    Score: 0.017
  50. Synergistic Cysteamine Delivery Nanowafer as an Efficacious Treatment Modality for Corneal Cystinosis. Mol Pharm. 2016 10 03; 13(10):3468-3477.
    View in: PubMed
    Score: 0.017
  51. Dexamethasone Drug Eluting Nanowafers Control Inflammation in Alkali-Burned Corneas Associated With Dry Eye. Invest Ophthalmol Vis Sci. 2016 06 01; 57(7):3222-30.
    View in: PubMed
    Score: 0.017
  52. Inflammatory Response to Lipopolysaccharide on the Ocular Surface in a Murine Dry Eye Model. Invest Ophthalmol Vis Sci. 2016 05 01; 57(6):2443-51.
    View in: PubMed
    Score: 0.017
  53. MMP-8 Is Critical for Dexamethasone Therapy in Alkali-Burned Corneas Under Dry Eye Conditions. J Cell Physiol. 2016 11; 231(11):2506-16.
    View in: PubMed
    Score: 0.017
  54. Differential Effects of Dexamethasone and Doxycycline on Inflammation and MMP Production in Murine Alkali-Burned Corneas Associated with Dry Eye. Ocul Surf. 2016 04; 14(2):242-54.
    View in: PubMed
    Score: 0.016
  55. Clusterin Seals the Ocular Surface Barrier in Mouse Dry Eye. PLoS One. 2015; 10(9):e0138958.
    View in: PubMed
    Score: 0.016
  56. Improvement of Outcome Measures of Dry Eye by a Novel Integrin Antagonist in the Murine Desiccating Stress Model. Invest Ophthalmol Vis Sci. 2015 Sep; 56(10):5888-95.
    View in: PubMed
    Score: 0.016
  57. Dexamethasone nanowafer as an effective therapy for dry eye disease. J Control Release. 2015 Sep 10; 213:168-174.
    View in: PubMed
    Score: 0.016
  58. Desiccating Stress-Induced MMP Production and Activity Worsens Wound Healing in Alkali-Burned Corneas. Invest Ophthalmol Vis Sci. 2015 Jul; 56(8):4908-18.
    View in: PubMed
    Score: 0.016
  59. Ocular drug delivery nanowafer with enhanced therapeutic efficacy. ACS Nano. 2015 Feb 24; 9(2):1749-58.
    View in: PubMed
    Score: 0.015
  60. Desiccating stress-induced chemokine expression in the epithelium is dependent on upregulation of NKG2D/RAE-1 and release of IFN-? in experimental dry eye. J Immunol. 2014 Nov 15; 193(10):5264-72.
    View in: PubMed
    Score: 0.015
  61. A potential link between bacterial pathogens and allergic conjunctivitis by dendritic cells. Exp Eye Res. 2014 Mar; 120:118-26.
    View in: PubMed
    Score: 0.014
  62. Ocular surface disease and dacryoadenitis in aging C57BL/6 mice. Am J Pathol. 2014 Mar; 184(3):631-43.
    View in: PubMed
    Score: 0.014
  63. Effect of desiccating stress on mouse meibomian gland function. Ocul Surf. 2014 Jan; 12(1):59-68.
    View in: PubMed
    Score: 0.014
  64. Morphologic alterations of the palpebral conjunctival epithelium in a dry eye model. Cornea. 2013 Apr; 32(4):483-90.
    View in: PubMed
    Score: 0.014
  65. Toll-like receptor expression and activation in mice with experimental dry eye. Invest Ophthalmol Vis Sci. 2013 Feb 28; 54(2):1554-63.
    View in: PubMed
    Score: 0.013
  66. Potential autocrine regulation of interleukin-33/ST2 signaling of dendritic cells in allergic inflammation. Mucosal Immunol. 2013 Sep; 6(5):921-30.
    View in: PubMed
    Score: 0.013
  67. Resolvin E1 (RX-10001) reduces corneal epithelial barrier disruption and protects against goblet cell loss in a murine model of dry eye. Cornea. 2012 Nov; 31(11):1299-303.
    View in: PubMed
    Score: 0.013
  68. Deletion of interferon-? delays onset and severity of dacryoadenitis in CD25KO mice. Arthritis Res Ther. 2012 Nov 01; 14(6):R234.
    View in: PubMed
    Score: 0.013
  69. Low humidity environmental challenge causes barrier disruption and cornification of the mouse corneal epithelium via a c-jun N-terminal kinase 2 (JNK2) pathway. Exp Eye Res. 2012 Jan; 94(1):150-6.
    View in: PubMed
    Score: 0.012
  70. Ocular surface APCs are necessary for autoreactive T cell-mediated experimental autoimmune lacrimal keratoconjunctivitis. J Immunol. 2011 Oct 01; 187(7):3653-62.
    View in: PubMed
    Score: 0.012
  71. Spontaneous autoimmune dacryoadenitis in aged CD25KO mice. Am J Pathol. 2010 Aug; 177(2):744-53.
    View in: PubMed
    Score: 0.011
  72. In vitro expanded CD4+CD25+Foxp3+ regulatory T cells maintain a normal phenotype and suppress immune-mediated ocular surface inflammation. Invest Ophthalmol Vis Sci. 2008 Dec; 49(12):5434-40.
    View in: PubMed
    Score: 0.010
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