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STEPHEN PFLUGFELDER to Epithelium, Corneal

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This is a "connection" page, showing publications STEPHEN PFLUGFELDER has written about Epithelium, Corneal.
STEPHEN PFLUGFELDER
Connection Strength
13.865
Epithelium, Corneal
  1. Induction of Innate Inflammatory Pathways in the Corneal Epithelium in the Desiccating Stress Dry Eye Model. Invest Ophthalmol Vis Sci. 2023 04 03; 64(4):8.
    View in: PubMed
    Score: 0.747
  2. Effects of L-carnitine, erythritol and betaine on pro-inflammatory markers in primary human corneal epithelial cells exposed to hyperosmotic stress. Curr Eye Res. 2015 Jul; 40(7):657-67.
    View in: PubMed
    Score: 0.414
  3. PROSE therapy used to minimize corneal trauma in patients with corneal epithelial defects. Am J Ophthalmol. 2013 Apr; 155(4):615-619, 619.e1-2.
    View in: PubMed
    Score: 0.365
  4. Desiccating stress induces CD4+ T-cell-mediated Sj?gren's syndrome-like corneal epithelial apoptosis via activation of the extrinsic apoptotic pathway by interferon-?. Am J Pathol. 2011 Oct; 179(4):1807-14.
    View in: PubMed
    Score: 0.334
  5. The successful use of Boston ocular surface prosthesis in the treatment of persistent corneal epithelial defect after herpes zoster ophthalmicus. Cornea. 2010 Dec; 29(12):1465-8.
    View in: PubMed
    Score: 0.318
  6. Suppressive effects of azithromycin on zymosan-induced production of proinflammatory mediators by human corneal epithelial cells. Invest Ophthalmol Vis Sci. 2010 Nov; 51(11):5623-9.
    View in: PubMed
    Score: 0.307
  7. Age-related T-cell cytokine profile parallels corneal disease severity in Sjogren's syndrome-like keratoconjunctivitis sicca in CD25KO mice. Rheumatology (Oxford). 2010 Feb; 49(2):246-58.
    View in: PubMed
    Score: 0.297
  8. Essential role for c-Jun N-terminal kinase 2 in corneal epithelial response to desiccating stress. Arch Ophthalmol. 2009 Dec; 127(12):1625-31.
    View in: PubMed
    Score: 0.296
  9. Association between high tear epidermal growth factor levels and corneal subepithelial fibrosis in dry eye conditions. Invest Ophthalmol Vis Sci. 2010 Feb; 51(2):844-9.
    View in: PubMed
    Score: 0.293
  10. Corneal epithelial opacity in dysfunctional tear syndrome. Am J Ophthalmol. 2009 Sep; 148(3):376-82.
    View in: PubMed
    Score: 0.288
  11. Glial cell-derived neurotrophic factor gene delivery enhances survival of human corneal epithelium in culture and the overexpression of GDNF in bioengineered constructs. Exp Eye Res. 2008 Dec; 87(6):580-6.
    View in: PubMed
    Score: 0.274
  12. Desiccating stress decreases apical corneal epithelial cell size--modulation by the metalloproteinase inhibitor doxycycline. Cornea. 2008 Sep; 27(8):935-40.
    View in: PubMed
    Score: 0.272
  13. Effects of contact lens multipurpose solutions on human corneal epithelial survival and barrier function. Eye Contact Lens. 2008 Sep; 34(5):281-6.
    View in: PubMed
    Score: 0.272
  14. Effects of osmoprotectants on hyperosmolar stress in cultured human corneal epithelial cells. Cornea. 2008 Jun; 27(5):574-9.
    View in: PubMed
    Score: 0.267
  15. Hyperosmolarity-induced cornification of human corneal epithelial cells is regulated by JNK MAPK. Invest Ophthalmol Vis Sci. 2008 Feb; 49(2):539-49.
    View in: PubMed
    Score: 0.261
  16. Nerve growth factor and its receptor TrkA serve as potential markers for human corneal epithelial progenitor cells. Exp Eye Res. 2008 Jan; 86(1):34-40.
    View in: PubMed
    Score: 0.254
  17. Strain-related cytokine profiles on the murine ocular surface in response to desiccating stress. Cornea. 2007 Jun; 26(5):579-84.
    View in: PubMed
    Score: 0.249
  18. Hyperosmolarity-induced apoptosis in human corneal epithelial cells is mediated by cytochrome c and MAPK pathways. Cornea. 2007 May; 26(4):452-60.
    View in: PubMed
    Score: 0.248
  19. Transglutaminase participates in UVB-induced cell death pathways in human corneal epithelial cells. Invest Ophthalmol Vis Sci. 2006 Oct; 47(10):4295-301.
    View in: PubMed
    Score: 0.238
  20. Is autologous serum a tonic for the ailing corneal epithelium? Am J Ophthalmol. 2006 Aug; 142(2):316-7.
    View in: PubMed
    Score: 0.235
  21. Desiccating stress stimulates expression of matrix metalloproteinases by the corneal epithelium. Invest Ophthalmol Vis Sci. 2006 Aug; 47(8):3293-302.
    View in: PubMed
    Score: 0.235
  22. Apical corneal barrier disruption in experimental murine dry eye is abrogated by methylprednisolone and doxycycline. Invest Ophthalmol Vis Sci. 2006 Jul; 47(7):2847-56.
    View in: PubMed
    Score: 0.234
  23. Expression and regulation of cornified envelope proteins in human corneal epithelium. Invest Ophthalmol Vis Sci. 2006 May; 47(5):1938-46.
    View in: PubMed
    Score: 0.231
  24. Corticosteroid and doxycycline suppress MMP-9 and inflammatory cytokine expression, MAPK activation in the corneal epithelium in experimental dry eye. Exp Eye Res. 2006 Sep; 83(3):526-35.
    View in: PubMed
    Score: 0.231
  25. Destructive and protective effects and therapeutic targets of IL-36 family cytokines in dry eye disease. Ocul Surf. 2025 Apr; 36:83-93.
    View in: PubMed
    Score: 0.211
  26. Matrix metalloproteinase-9 knockout confers resistance to corneal epithelial barrier disruption in experimental dry eye. Am J Pathol. 2005 Jan; 166(1):61-71.
    View in: PubMed
    Score: 0.211
  27. Stimulation of matrix metalloproteinases by hyperosmolarity via a JNK pathway in human corneal epithelial cells. Invest Ophthalmol Vis Sci. 2004 Dec; 45(12):4302-11.
    View in: PubMed
    Score: 0.210
  28. Ectoine protects corneal epithelial survival and barrier from hyperosmotic stress by promoting anti-inflammatory cytokine IL-37. Ocul Surf. 2024 Apr; 32:182-191.
    View in: PubMed
    Score: 0.199
  29. Corneal epitheliopathy of dry eye induces hyperesthesia to mechanical air jet stimulation. Am J Ophthalmol. 2004 Jan; 137(1):109-15.
    View in: PubMed
    Score: 0.197
  30. Regulated expression of collagenases MMP-1, -8, and -13 and stromelysins MMP-3, -10, and -11 by human corneal epithelial cells. Invest Ophthalmol Vis Sci. 2003 Jul; 44(7):2928-36.
    View in: PubMed
    Score: 0.190
  31. Imbalanced IL-37/TNF-a/CTSS signaling disrupts corneal epithelial barrier in a dry eye model in vitro. Ocul Surf. 2022 10; 26:234-243.
    View in: PubMed
    Score: 0.181
  32. Regulation of MMP-9 production by human corneal epithelial cells. Exp Eye Res. 2001 Oct; 73(4):449-59.
    View in: PubMed
    Score: 0.168
  33. IL-36a/IL-36RA/IL-38 signaling mediates inflammation and barrier disruption in human corneal epithelial cells under hyperosmotic stress. Ocul Surf. 2021 10; 22:163-171.
    View in: PubMed
    Score: 0.167
  34. Single-Cell Transcriptomics Identifies a Unique Entity and Signature Markers of Transit-Amplifying Cells in Human Corneal Limbus. Invest Ophthalmol Vis Sci. 2021 07 01; 62(9):36.
    View in: PubMed
    Score: 0.165
  35. Conjunctivochalasis and Tear Osmolarity Are Associated With Reduced Conjunctival Epithelial Thickness in Dry Eye. Am J Ophthalmol. 2021 07; 227:35-44.
    View in: PubMed
    Score: 0.161
  36. Expression of the receptor tyrosine kinases, epidermal growth factor receptor, ErbB2, and ErbB3, in human ocular surface epithelia. Cornea. 2001 Jan; 20(1):81-5.
    View in: PubMed
    Score: 0.160
  37. Single-cell transcriptomics identifies limbal stem cell population and cell types mapping its differentiation trajectory in limbal basal epithelium of human cornea. Ocul Surf. 2021 04; 20:20-32.
    View in: PubMed
    Score: 0.160
  38. Correlation of the Schirmer 1 and fluorescein clearance tests with the severity of corneal epithelial and eyelid disease. Arch Ophthalmol. 2000 Dec; 118(12):1632-8.
    View in: PubMed
    Score: 0.159
  39. Trehalose Induces Autophagy Against Inflammation by Activating TFEB Signaling Pathway in Human Corneal Epithelial Cells Exposed to Hyperosmotic Stress. Invest Ophthalmol Vis Sci. 2020 08 03; 61(10):26.
    View in: PubMed
    Score: 0.155
  40. Doxycycline inhibition of interleukin-1 in the corneal epithelium. Invest Ophthalmol Vis Sci. 2000 Aug; 41(9):2544-57.
    View in: PubMed
    Score: 0.155
  41. Regulation of MMP-9 activity in human tear fluid and corneal epithelial culture supernatant. Invest Ophthalmol Vis Sci. 2000 Jun; 41(7):1703-9.
    View in: PubMed
    Score: 0.153
  42. IL-33/ST2/IL-9/IL-9R signaling disrupts ocular surface barrier in allergic inflammation. Mucosal Immunol. 2020 11; 13(6):919-930.
    View in: PubMed
    Score: 0.153
  43. Detection of sialomucin complex (MUC4) in human ocular surface epithelium and tear fluid. Invest Ophthalmol Vis Sci. 2000 May; 41(6):1316-26.
    View in: PubMed
    Score: 0.153
  44. Topical Recombinant Human Nerve Growth Factor (Cenegermin) for Neurotrophic Keratopathy: A Multicenter Randomized Vehicle-Controlled Pivotal Trial. Ophthalmology. 2020 01; 127(1):14-26.
    View in: PubMed
    Score: 0.145
  45. Reduced intraepithelial corneal nerve density and sensitivity accompany desiccating stress and aging in C57BL/6 mice. Exp Eye Res. 2018 04; 169:91-98.
    View in: PubMed
    Score: 0.131
  46. The Pathophysiology of Dry Eye Disease: What We Know and Future Directions for Research. Ophthalmology. 2017 11; 124(11S):S4-S13.
    View in: PubMed
    Score: 0.128
  47. Identification for Differential Localization of Putative Corneal Epithelial Stem Cells in Mouse and Human. Sci Rep. 2017 07 12; 7(1):5169.
    View in: PubMed
    Score: 0.126
  48. Mitochondrial DNA oxidation induces imbalanced activity of NLRP3/NLRP6 inflammasomes by activation of caspase-8 and BRCC36 in dry eye. J Autoimmun. 2017 Jun; 80:65-76.
    View in: PubMed
    Score: 0.122
  49. A hyaluronan hydrogel scaffold-based xeno-free culture system for ex vivo expansion of human corneal epithelial stem cells. Eye (Lond). 2017 Jun; 31(6):962-971.
    View in: PubMed
    Score: 0.122
  50. Blueberry Component Pterostilbene Protects Corneal Epithelial Cells from Inflammation via Anti-oxidative Pathway. Sci Rep. 2016 Jan 14; 6:19408.
    View in: PubMed
    Score: 0.113
  51. Protective Effects of L-Carnitine Against Oxidative Injury by Hyperosmolarity in Human Corneal Epithelial Cells. Invest Ophthalmol Vis Sci. 2015 Aug; 56(9):5503-11.
    View in: PubMed
    Score: 0.110
  52. A Novel Innate Response of Human Corneal Epithelium to Heat-killed Candida albicans by Producing Peptidoglycan Recognition Proteins. PLoS One. 2015; 10(6):e0128039.
    View in: PubMed
    Score: 0.109
  53. Unique expression pattern and functional role of periostin in human limbal stem cells. PLoS One. 2015; 10(2):e0117139.
    View in: PubMed
    Score: 0.106
  54. Desiccating stress-induced chemokine expression in the epithelium is dependent on upregulation of NKG2D/RAE-1 and release of IFN-? in experimental dry eye. J Immunol. 2014 Nov 15; 193(10):5264-72.
    View in: PubMed
    Score: 0.104
  55. Human corneal epithelial cells produce antimicrobial peptides LL-37 and ?-defensins in response to heat-killed Candida albicans. Ophthalmic Res. 2014; 51(4):179-86.
    View in: PubMed
    Score: 0.100
  56. A novel interleukin 33/ST2 signaling regulates inflammatory response in human corneal epithelium. PLoS One. 2013; 8(4):e60963.
    View in: PubMed
    Score: 0.093
  57. A native-like corneal construct using donor corneal stroma for tissue engineering. PLoS One. 2012; 7(11):e49571.
    View in: PubMed
    Score: 0.091
  58. Resolvin E1 (RX-10001) reduces corneal epithelial barrier disruption and protects against goblet cell loss in a murine model of dry eye. Cornea. 2012 Nov; 31(11):1299-303.
    View in: PubMed
    Score: 0.091
  59. Identification of human fibroblast cell lines as a feeder layer for human corneal epithelial regeneration. PLoS One. 2012; 7(6):e38825.
    View in: PubMed
    Score: 0.088
  60. Transcription factor TCF4 maintains the properties of human corneal epithelial stem cells. Stem Cells. 2012 Apr; 30(4):753-61.
    View in: PubMed
    Score: 0.087
  61. Low humidity environmental challenge causes barrier disruption and cornification of the mouse corneal epithelium via a c-jun N-terminal kinase 2 (JNK2) pathway. Exp Eye Res. 2012 Jan; 94(1):150-6.
    View in: PubMed
    Score: 0.085
  62. TLR-mediated induction of pro-allergic cytokine IL-33 in ocular mucosal epithelium. Int J Biochem Cell Biol. 2011 Sep; 43(9):1383-91.
    View in: PubMed
    Score: 0.082
  63. The ?-catenin/Tcf4/survivin signaling maintains a less differentiated phenotype and high proliferative capacity of human corneal epithelial progenitor cells. Int J Biochem Cell Biol. 2011 May; 43(5):751-9.
    View in: PubMed
    Score: 0.080
  64. An immunoprotective privilege of corneal epithelial stem cells against Th17 inflammatory stress by producing glial cell-derived neurotrophic factor. Stem Cells. 2010 Dec; 28(12):2172-81.
    View in: PubMed
    Score: 0.079
  65. Altered morphology and function of the lacrimal functional unit in protein kinase C{alpha} knockout mice. Invest Ophthalmol Vis Sci. 2010 Nov; 51(11):5592-600.
    View in: PubMed
    Score: 0.077
  66. Molecular signatures and biological pathway profiles of human corneal epithelial progenitor cells. Int J Biochem Cell Biol. 2010 Jul; 42(7):1142-53.
    View in: PubMed
    Score: 0.076
  67. Induction of Th17 differentiation by corneal epithelial-derived cytokines. J Cell Physiol. 2010 Jan; 222(1):95-102.
    View in: PubMed
    Score: 0.075
  68. Toll-like receptors mediate induction of peptidoglycan recognition proteins in human corneal epithelial cells. Exp Eye Res. 2010 Jan; 90(1):130-6.
    View in: PubMed
    Score: 0.073
  69. Production and activity of matrix metalloproteinase-9 on the ocular surface increase in dysfunctional tear syndrome. Invest Ophthalmol Vis Sci. 2009 Jul; 50(7):3203-9.
    View in: PubMed
    Score: 0.070
  70. IL-17 disrupts corneal barrier following desiccating stress. Mucosal Immunol. 2009 May; 2(3):243-53.
    View in: PubMed
    Score: 0.070
  71. Human corneal epithelium-derived thymic stromal lymphopoietin links the innate and adaptive immune responses via TLRs and Th2 cytokines. Invest Ophthalmol Vis Sci. 2009 Jun; 50(6):2702-9.
    View in: PubMed
    Score: 0.070
  72. Expression of glial cell-derived neurotrophic factor and its receptor in the stem-cell-containing human limbal epithelium. Br J Ophthalmol. 2008 Sep; 92(9):1269-74.
    View in: PubMed
    Score: 0.068
  73. Improved transduction of human corneal epithelial progenitor cells with cell-targeting adenoviral vectors. Exp Eye Res. 2006 Oct; 83(4):798-806.
    View in: PubMed
    Score: 0.058
  74. Cell size correlates with phenotype and proliferative capacity in human corneal epithelial cells. Stem Cells. 2006 Feb; 24(2):368-75.
    View in: PubMed
    Score: 0.055
  75. Doxycycline inhibits TGF-beta1-induced MMP-9 via Smad and MAPK pathways in human corneal epithelial cells. Invest Ophthalmol Vis Sci. 2005 Mar; 46(3):840-8.
    View in: PubMed
    Score: 0.053
  76. Experimental dry eye stimulates production of inflammatory cytokines and MMP-9 and activates MAPK signaling pathways on the ocular surface. Invest Ophthalmol Vis Sci. 2004 Dec; 45(12):4293-301.
    View in: PubMed
    Score: 0.052
  77. TGF-beta1 stimulates production of gelatinase (MMP-9), collagenases (MMP-1, -13) and stromelysins (MMP-3, -10, -11) by human corneal epithelial cells. Exp Eye Res. 2004 Aug; 79(2):263-74.
    View in: PubMed
    Score: 0.051
  78. Phenotypic characterization of human corneal epithelial cells expanded ex vivo from limbal explant and single cell cultures. Exp Eye Res. 2004 Jul; 79(1):41-9.
    View in: PubMed
    Score: 0.051
  79. Ectoine Enhances Mucin Production Via Restoring IL-13/IFN-? Balance in a Murine Dry Eye Model. Invest Ophthalmol Vis Sci. 2024 Jun 03; 65(6):39.
    View in: PubMed
    Score: 0.051
  80. Characterization of putative stem cell phenotype in human limbal epithelia. Stem Cells. 2004; 22(3):355-66.
    View in: PubMed
    Score: 0.049
  81. A mouse model of keratoconjunctivitis sicca. Invest Ophthalmol Vis Sci. 2002 Mar; 43(3):632-8.
    View in: PubMed
    Score: 0.043
  82. Treatment of recalcitrant recurrent corneal erosions with inhibitors of matrix metalloproteinase-9, doxycycline and corticosteroids. Am J Ophthalmol. 2001 Jul; 132(1):8-13.
    View in: PubMed
    Score: 0.041
  83. Suppression of interleukin 1alpha and interleukin 1beta in human limbal epithelial cells cultured on the amniotic membrane stromal matrix. Br J Ophthalmol. 2001 Apr; 85(4):444-9.
    View in: PubMed
    Score: 0.041
  84. Autophagy Activation Protects Ocular Surface from Inflammation in a Dry Eye Model In Vitro. Int J Mol Sci. 2020 Nov 26; 21(23).
    View in: PubMed
    Score: 0.040
  85. Potential localization of putative stem/progenitor cells in human bulbar conjunctival epithelium. J Cell Physiol. 2010 Oct; 225(1):180-5.
    View in: PubMed
    Score: 0.020
  86. TSLP and downstream molecules in experimental mouse allergic conjunctivitis. Invest Ophthalmol Vis Sci. 2010 Jun; 51(6):3076-82.
    View in: PubMed
    Score: 0.019
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.