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STEPHEN PFLUGFELDER to Conjunctiva

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This is a "connection" page, showing publications STEPHEN PFLUGFELDER has written about Conjunctiva.
STEPHEN PFLUGFELDER
Connection Strength
16.639
Conjunctiva
  1. Changes in conjunctival mononuclear phagocytes and suppressive activity of regulatory macrophages in desiccation induced dry eye. Ocul Surf. 2024 Oct; 34:348-362.
    View in: PubMed
    Score: 0.793
  2. Differentially Expressed Gene Pathways in the Conjunctiva of Sj?gren Syndrome Keratoconjunctivitis Sicca. Front Immunol. 2021; 12:702755.
    View in: PubMed
    Score: 0.636
  3. Desiccation Induced Conjunctival Monocyte Recruitment and Activation - Implications for Keratoconjunctivitis. Front Immunol. 2021; 12:701415.
    View in: PubMed
    Score: 0.635
  4. Conjunctivochalasis and Tear Osmolarity Are Associated With Reduced Conjunctival Epithelial Thickness in Dry Eye. Am J Ophthalmol. 2021 07; 227:35-44.
    View in: PubMed
    Score: 0.617
  5. Goblet cells promote tolerance induction in the conjunctiva. Mucosal Immunol. 2020 09; 13(5):717-718.
    View in: PubMed
    Score: 0.592
  6. Immune - Goblet cell interaction in the conjunctiva. Ocul Surf. 2020 04; 18(2):326-334.
    View in: PubMed
    Score: 0.573
  7. Goblet cell loss abrogates ocular surface immune tolerance. JCI Insight. 2018 02 08; 3(3).
    View in: PubMed
    Score: 0.501
  8. Goblet Cells Contribute to Ocular Surface Immune Tolerance-Implications for Dry Eye Disease. Int J Mol Sci. 2017 May 05; 18(5).
    View in: PubMed
    Score: 0.476
  9. Randomized Controlled Crossover Trial Comparing the Impact of Sham or Intranasal Tear Neurostimulation on Conjunctival Goblet Cell Degranulation. Am J Ophthalmol. 2017 May; 177:159-168.
    View in: PubMed
    Score: 0.471
  10. Altered Mucosal Microbiome Diversity and Disease Severity in Sj?gren Syndrome. Sci Rep. 2016 Apr 18; 6:23561.
    View in: PubMed
    Score: 0.442
  11. Aqueous Tear Deficiency Increases Conjunctival Interferon-? (IFN-?) Expression and Goblet Cell Loss. Invest Ophthalmol Vis Sci. 2015 Nov; 56(12):7545-50.
    View in: PubMed
    Score: 0.428
  12. IL-13 Stimulates Proliferation and Expression of Mucin and Immunomodulatory Genes in Cultured Conjunctival Goblet Cells. Invest Ophthalmol Vis Sci. 2015 Jul; 56(8):4186-97.
    View in: PubMed
    Score: 0.418
  13. Macrophage Phenotype in the Ocular Surface of Experimental Murine Dry Eye Disease. Arch Immunol Ther Exp (Warsz). 2015 Aug; 63(4):299-304.
    View in: PubMed
    Score: 0.410
  14. Topical interferon-gamma neutralization prevents conjunctival goblet cell loss in experimental murine dry eye. Exp Eye Res. 2014 Jan; 118:117-24.
    View in: PubMed
    Score: 0.375
  15. Factors predicting the ocular surface response to desiccating environmental stress. Invest Ophthalmol Vis Sci. 2013 May 07; 54(5):3325-32.
    View in: PubMed
    Score: 0.361
  16. Interferon-? exacerbates dry eye-induced apoptosis in conjunctiva through dual apoptotic pathways. Invest Ophthalmol Vis Sci. 2011 Aug 09; 52(9):6279-85.
    View in: PubMed
    Score: 0.319
  17. Entrapment of conjunctival goblet cells by desiccation-induced cornification. Invest Ophthalmol Vis Sci. 2011 Jun 01; 52(6):3492-9.
    View in: PubMed
    Score: 0.315
  18. Homeostatic control of conjunctival mucosal goblet cells by NKT-derived IL-13. Mucosal Immunol. 2011 Jul; 4(4):397-408.
    View in: PubMed
    Score: 0.306
  19. Anterior segment optical coherence tomography: a diagnostic instrument for conjunctivochalasis. Am J Ophthalmol. 2010 Dec; 150(6):798-806.
    View in: PubMed
    Score: 0.305
  20. Desiccating stress promotion of Th17 differentiation by ocular surface tissues through a dendritic cell-mediated pathway. Invest Ophthalmol Vis Sci. 2010 Jun; 51(6):3083-91.
    View in: PubMed
    Score: 0.288
  21. Expression of CXCL9, -10, -11, and CXCR3 in the tear film and ocular surface of patients with dry eye syndrome. Invest Ophthalmol Vis Sci. 2010 Feb; 51(2):643-50.
    View in: PubMed
    Score: 0.282
  22. Immunoregulation on the ocular surface: 2nd Cullen Symposium. Ocul Surf. 2009 Apr; 7(2):67-77.
    View in: PubMed
    Score: 0.271
  23. Effects of sequential artificial tear and cyclosporine emulsion therapy on conjunctival goblet cell density and transforming growth factor-beta2 production. Cornea. 2008 Jan; 27(1):64-9.
    View in: PubMed
    Score: 0.249
  24. Dry eye-induced conjunctival epithelial squamous metaplasia is modulated by interferon-gamma. Invest Ophthalmol Vis Sci. 2007 Jun; 48(6):2553-60.
    View in: PubMed
    Score: 0.239
  25. Expression of Th-1 chemokines and chemokine receptors on the ocular surface of C57BL/6 mice: effects of desiccating stress. Invest Ophthalmol Vis Sci. 2007 Jun; 48(6):2561-9.
    View in: PubMed
    Score: 0.239
  26. Strain-related cytokine profiles on the murine ocular surface in response to desiccating stress. Cornea. 2007 Jun; 26(5):579-84.
    View in: PubMed
    Score: 0.239
  27. JNK and ERK MAP kinases mediate induction of IL-1beta, TNF-alpha and IL-8 following hyperosmolar stress in human limbal epithelial cells. Exp Eye Res. 2006 Apr; 82(4):588-96.
    View in: PubMed
    Score: 0.213
  28. Hyperosmolar saline is a proinflammatory stress on the mouse ocular surface. Eye Contact Lens. 2005 Sep; 31(5):186-93.
    View in: PubMed
    Score: 0.212
  29. Topical cyclosporine inhibits conjunctival epithelial apoptosis in experimental murine keratoconjunctivitis sicca. Cornea. 2005 Jan; 24(1):80-5.
    View in: PubMed
    Score: 0.202
  30. Immunologic basis for development of keratoconjunctivitis sicca in systemic autoimmune diseases: Role of innate immune sensors. Ocul Surf. 2024 Apr; 32:130-138.
    View in: PubMed
    Score: 0.190
  31. Comparison of Efficacy and Inflammatory Response to Thermoconjunctivoplasty Performed with Cautery or Pulsed 1460 nm Laser. Int J Mol Sci. 2023 Mar 17; 24(6).
    View in: PubMed
    Score: 0.179
  32. Apoptosis of ocular surface cells in experimentally induced dry eye. Invest Ophthalmol Vis Sci. 2003 Jan; 44(1):124-9.
    View in: PubMed
    Score: 0.176
  33. Non-Invasive Tear Break-Up Detection with the Kowa DR-1a and Its Relationship to Dry Eye Clinical Severity. Int J Mol Sci. 2022 Nov 25; 23(23).
    View in: PubMed
    Score: 0.175
  34. Single-cell transcriptional profiling of murine conjunctival immune cells reveals distinct populations expressing homeostatic and regulatory genes. Mucosal Immunol. 2022 04; 15(4):620-628.
    View in: PubMed
    Score: 0.167
  35. Pro- and anti-inflammatory forms of interleukin-1 in the tear fluid and conjunctiva of patients with dry-eye disease. Invest Ophthalmol Vis Sci. 2001 Sep; 42(10):2283-92.
    View in: PubMed
    Score: 0.160
  36. Retinoid Regulation of Ocular Surface Innate Inflammation. Int J Mol Sci. 2021 Jan 22; 22(3).
    View in: PubMed
    Score: 0.154
  37. Expression of the receptor tyrosine kinases, epidermal growth factor receptor, ErbB2, and ErbB3, in human ocular surface epithelia. Cornea. 2001 Jan; 20(1):81-5.
    View in: PubMed
    Score: 0.153
  38. Inflammatory basis for dry eye disease flares. Exp Eye Res. 2020 12; 201:108294.
    View in: PubMed
    Score: 0.151
  39. Calcineurin Inhibitor Voclosporin Preserves Corneal Barrier and Conjunctival Goblet Cells in Experimental Dry Eye. J Ocul Pharmacol Ther. 2020 11; 36(9):679-685.
    View in: PubMed
    Score: 0.149
  40. Detection of sialomucin complex (MUC4) in human ocular surface epithelium and tear fluid. Invest Ophthalmol Vis Sci. 2000 May; 41(6):1316-26.
    View in: PubMed
    Score: 0.146
  41. Increased expression of the type 1 growth factor receptor family in the conjunctival epithelium of patients with keratoconjunctivitis sicca. Am J Ophthalmol. 2000 Apr; 129(4):472-80.
    View in: PubMed
    Score: 0.145
  42. Dysbiosis Modulates Ocular Surface Inflammatory Response to Liposaccharide. Invest Ophthalmol Vis Sci. 2019 10 01; 60(13):4224-4233.
    View in: PubMed
    Score: 0.140
  43. Altered cytokine balance in the tear fluid and conjunctiva of patients with Sj?gren's syndrome keratoconjunctivitis sicca. Curr Eye Res. 1999 Sep; 19(3):201-11.
    View in: PubMed
    Score: 0.140
  44. The pathology of dry eye: the interaction between the ocular surface and lacrimal glands. Cornea. 1998 Nov; 17(6):584-9.
    View in: PubMed
    Score: 0.132
  45. Near-infrared laser thermal conjunctivoplasty. Sci Rep. 2018 03 01; 8(1):3863.
    View in: PubMed
    Score: 0.126
  46. Alterations of ocular surface gene expression in Sj?gren's syndrome. Adv Exp Med Biol. 1998; 438:533-6.
    View in: PubMed
    Score: 0.124
  47. Tear fluid influence on the ocular surface. Adv Exp Med Biol. 1998; 438:611-7.
    View in: PubMed
    Score: 0.124
  48. A unified theory of the role of the ocular surface in dry eye. Adv Exp Med Biol. 1998; 438:643-51.
    View in: PubMed
    Score: 0.124
  49. Study design and baseline findings from the progression of ocular findings (PROOF) natural history study of dry eye. BMC Ophthalmol. 2017 Dec 28; 17(1):265.
    View in: PubMed
    Score: 0.124
  50. The Pathophysiology of Dry Eye Disease: What We Know and Future Directions for Research. Ophthalmology. 2017 11; 124(11S):S4-S13.
    View in: PubMed
    Score: 0.123
  51. Correlation of goblet cell density and mucosal epithelial membrane mucin expression with rose bengal staining in patients with ocular irritation. Ophthalmology. 1997 Feb; 104(2):223-35.
    View in: PubMed
    Score: 0.117
  52. Anterior Segment Optical Coherence Tomography (AS-OCT) in the Management of Dry Eye. Int Ophthalmol Clin. 2017; 57(2):13-22.
    View in: PubMed
    Score: 0.116
  53. Interferon-gamma deficiency protects against aging-related goblet cell loss. Oncotarget. 2016 10 04; 7(40):64605-64614.
    View in: PubMed
    Score: 0.114
  54. Inflammatory Response to Lipopolysaccharide on the Ocular Surface in a Murine Dry Eye Model. Invest Ophthalmol Vis Sci. 2016 05 01; 57(6):2443-51.
    View in: PubMed
    Score: 0.111
  55. Interferon-?-Induced Unfolded Protein Response in Conjunctival Goblet Cells as a Cause of Mucin Deficiency in Sj?gren Syndrome. Am J Pathol. 2016 06; 186(6):1547-58.
    View in: PubMed
    Score: 0.110
  56. Effects of Dry Eye Therapies on Environmentally Induced Ocular Surface Disease. Am J Ophthalmol. 2015 Jul; 160(1):135-42.e1.
    View in: PubMed
    Score: 0.103
  57. Sj?gren's syndrome: cytokine and Epstein-Barr viral gene expression within the conjunctival epithelium. Invest Ophthalmol Vis Sci. 1994 Aug; 35(9):3493-504.
    View in: PubMed
    Score: 0.098
  58. Complications related to a cosmetic eye-whitening procedure. Am J Ophthalmol. 2014 Nov; 158(5):967-73.
    View in: PubMed
    Score: 0.098
  59. Tear meniscus dimensions in tear dysfunction and their correlation with clinical parameters. Am J Ophthalmol. 2014 Feb; 157(2):301-310.e1.
    View in: PubMed
    Score: 0.093
  60. Disruption of TGF-? signaling improves ocular surface epithelial disease in experimental autoimmune keratoconjunctivitis sicca. PLoS One. 2011; 6(12):e29017.
    View in: PubMed
    Score: 0.082
  61. Potential localization of putative stem/progenitor cells in human bulbar conjunctival epithelium. J Cell Physiol. 2010 Oct; 225(1):180-5.
    View in: PubMed
    Score: 0.075
  62. Conjunctival cytologic features of primary Sj?gren's syndrome. Ophthalmology. 1990 Aug; 97(8):985-91.
    View in: PubMed
    Score: 0.074
  63. Age-related T-cell cytokine profile parallels corneal disease severity in Sjogren's syndrome-like keratoconjunctivitis sicca in CD25KO mice. Rheumatology (Oxford). 2010 Feb; 49(2):246-58.
    View in: PubMed
    Score: 0.071
  64. Corneal epithelial opacity in dysfunctional tear syndrome. Am J Ophthalmol. 2009 Sep; 148(3):376-82.
    View in: PubMed
    Score: 0.069
  65. Production and activity of matrix metalloproteinase-9 on the ocular surface increase in dysfunctional tear syndrome. Invest Ophthalmol Vis Sci. 2009 Jul; 50(7):3203-9.
    View in: PubMed
    Score: 0.067
  66. IL-17 disrupts corneal barrier following desiccating stress. Mucosal Immunol. 2009 May; 2(3):243-53.
    View in: PubMed
    Score: 0.067
  67. Future directions in therapeutic interventions for conjunctival inflammatory disorders. Curr Opin Allergy Clin Immunol. 2007 Oct; 7(5):450-3.
    View in: PubMed
    Score: 0.061
  68. Experimental dry eye stimulates production of inflammatory cytokines and MMP-9 and activates MAPK signaling pathways on the ocular surface. Invest Ophthalmol Vis Sci. 2004 Dec; 45(12):4293-301.
    View in: PubMed
    Score: 0.050
  69. Ectoine Enhances Mucin Production Via Restoring IL-13/IFN-? Balance in a Murine Dry Eye Model. Invest Ophthalmol Vis Sci. 2024 Jun 03; 65(6):39.
    View in: PubMed
    Score: 0.049
  70. Differentially Expressed Tear Proteins in Sj?gren's Syndrome Keratoconjunctivitis Sicca. Transl Vis Sci Technol. 2023 06 01; 12(6):8.
    View in: PubMed
    Score: 0.045
  71. A mouse model of keratoconjunctivitis sicca. Invest Ophthalmol Vis Sci. 2002 Mar; 43(3):632-8.
    View in: PubMed
    Score: 0.042
  72. Experimentally induced dry eye produces ocular surface inflammation and epithelial disease. Adv Exp Med Biol. 2002; 506(Pt A):647-55.
    View in: PubMed
    Score: 0.041
  73. The effect of punctal occlusion on tear production, tear clearance, and ocular surface sensation in normal subjects. Am J Ophthalmol. 2001 Mar; 131(3):314-23.
    View in: PubMed
    Score: 0.039
  74. Rapamycin Eyedrops Increased CD4+Foxp3+ Cells and Prevented Goblet Cell Loss in the Aged Ocular Surface. Int J Mol Sci. 2020 Nov 24; 21(23).
    View in: PubMed
    Score: 0.038
  75. A standardized visual scale for evaluation of tear fluorescein clearance. Ophthalmology. 2000 Jul; 107(7):1338-43.
    View in: PubMed
    Score: 0.037
  76. Interleukin-6 levels in the conjunctival epithelium of patients with dry eye disease treated with cyclosporine ophthalmic emulsion. Cornea. 2000 Jul; 19(4):492-6.
    View in: PubMed
    Score: 0.037
  77. Pollen/TLR4 Innate Immunity Signaling Initiates IL-33/ST2/Th2 Pathways in Allergic Inflammation. Sci Rep. 2016 10 31; 6:36150.
    View in: PubMed
    Score: 0.029
  78. Desiccating stress-induced chemokine expression in the epithelium is dependent on upregulation of NKG2D/RAE-1 and release of IFN-? in experimental dry eye. J Immunol. 2014 Nov 15; 193(10):5264-72.
    View in: PubMed
    Score: 0.025
  79. Chemokine receptors CCR6 and CXCR3 are necessary for CD4(+) T cell mediated ocular surface disease in experimental dry eye disease. PLoS One. 2013; 8(11):e78508.
    View in: PubMed
    Score: 0.023
  80. Long-term Supplementation With n-6 and n-3 PUFAs Improves Moderate-to-Severe Keratoconjunctivitis Sicca: A Randomized Double-Blind Clinical Trial. Cornea. 2013 Oct; 32(10):1297-304.
    View in: PubMed
    Score: 0.023
  81. Dendritic cell-derived thrombospondin-1 is critical for the generation of the ocular surface Th17 response to desiccating stress. J Leukoc Biol. 2013 Dec; 94(6):1293-301.
    View in: PubMed
    Score: 0.023
  82. Morphologic alterations of the palpebral conjunctival epithelium in a dry eye model. Cornea. 2013 Apr; 32(4):483-90.
    View in: PubMed
    Score: 0.022
  83. Cytoskeletal antigen expression in ocular mucosa-associated lymphoid tissue. Invest Ophthalmol Vis Sci. 1992 Oct; 33(11):3235-41.
    View in: PubMed
    Score: 0.022
  84. NK cells promote Th-17 mediated corneal barrier disruption in dry eye. PLoS One. 2012; 7(5):e36822.
    View in: PubMed
    Score: 0.021
  85. TSLP and downstream molecules in experimental mouse allergic conjunctivitis. Invest Ophthalmol Vis Sci. 2010 Jun; 51(6):3076-82.
    View in: PubMed
    Score: 0.018
  86. Therapy of nonnecrotizing anterior scleritis with subconjunctival corticosteroid injection. Ophthalmology. 1995 May; 102(5):718-24.
    View in: PubMed
    Score: 0.006
  87. Detection of the complement (CD21)/Epstein-Barr virus receptor in human lacrimal gland and ocular surface epithelia. Reg Immunol. 1990-1991; 3(4):164-70.
    View in: PubMed
    Score: 0.004
  88. Lymphogranuloma venereum conjunctivitis with a marginal corneal perforation. Ophthalmology. 1988 Jun; 95(6):799-802.
    View in: PubMed
    Score: 0.004
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The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.