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LANLAN SHEN to DNA Methylation

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This is a "connection" page, showing publications LANLAN SHEN has written about DNA Methylation.
LANLAN SHEN
Connection Strength
5.388
DNA Methylation
  1. DNA methylation profiling at base-pair resolution reveals unique epigenetic features of early-onset colorectal cancer in underrepresented populations. Clin Epigenetics. 2025 Jan 22; 17(1):11.
    View in: PubMed
    Score: 0.563
  2. Postnatal epigenetic regulation of intestinal stem cells requires DNA methylation and is guided by the microbiome. Genome Biol. 2015 Sep 30; 16:211.
    View in: PubMed
    Score: 0.295
  3. Developmentally programmed 3' CpG island methylation confers tissue- and cell-type-specific transcriptional activation. Mol Cell Biol. 2013 May; 33(9):1845-58.
    View in: PubMed
    Score: 0.247
  4. DNA methylation predicts survival and response to therapy in patients with myelodysplastic syndromes. J Clin Oncol. 2010 Feb 01; 28(4):605-13.
    View in: PubMed
    Score: 0.198
  5. Epigenomic profiling indicates a role for DNA methylation in early postnatal liver development. Hum Mol Genet. 2009 Aug 15; 18(16):3026-38.
    View in: PubMed
    Score: 0.190
  6. Drug sensitivity prediction by CpG island methylation profile in the NCI-60 cancer cell line panel. Cancer Res. 2007 Dec 01; 67(23):11335-43.
    View in: PubMed
    Score: 0.172
  7. Association between DNA methylation and shortened survival in patients with advanced colorectal cancer treated with 5-fluorouracil based chemotherapy. Clin Cancer Res. 2007 Oct 15; 13(20):6093-8.
    View in: PubMed
    Score: 0.170
  8. Genome-wide profiling of DNA methylation reveals a class of normally methylated CpG island promoters. PLoS Genet. 2007 Oct; 3(10):2023-36.
    View in: PubMed
    Score: 0.169
  9. Methods of DNA methylation analysis. Curr Opin Clin Nutr Metab Care. 2007 Sep; 10(5):576-81.
    View in: PubMed
    Score: 0.169
  10. Optimizing annealing temperature overcomes bias in bisulfite PCR methylation analysis. Biotechniques. 2007 Jan; 42(1):48, 50, 52 passim.
    View in: PubMed
    Score: 0.161
  11. MGMT promoter methylation and field defect in sporadic colorectal cancer. J Natl Cancer Inst. 2005 Sep 21; 97(18):1330-8.
    View in: PubMed
    Score: 0.147
  12. Global DNA methylation differences involving germline structural variation impact gene expression in pediatric brain tumors. Nat Commun. 2025 May 21; 16(1):4713.
    View in: PubMed
    Score: 0.144
  13. The DNA methylome of pediatric brain tumors appears shaped by structural variation and predicts survival. Nat Commun. 2024 Aug 08; 15(1):6775.
    View in: PubMed
    Score: 0.136
  14. Functional characterization of age-dependent p16 epimutation reveals biological drivers and therapeutic targets for colorectal cancer. J Exp Clin Cancer Res. 2023 May 04; 42(1):113.
    View in: PubMed
    Score: 0.125
  15. P14 methylation in human colon cancer is associated with microsatellite instability and wild-type p53. Gastroenterology. 2003 Mar; 124(3):626-33.
    View in: PubMed
    Score: 0.123
  16. Aberrant DNA methylation of p57KIP2 identifies a cell-cycle regulatory pathway with prognostic impact in adult acute lymphocytic leukemia. Blood. 2003 May 15; 101(10):4131-6.
    View in: PubMed
    Score: 0.123
  17. Lack of p21(CIP1) DNA methylation in acute lymphocytic leukemia. Blood. 2002 Nov 01; 100(9):3432-3; author reply 3433-4.
    View in: PubMed
    Score: 0.121
  18. DNA methylation and environmental exposures in human hepatocellular carcinoma. J Natl Cancer Inst. 2002 May 15; 94(10):755-61.
    View in: PubMed
    Score: 0.117
  19. The concurrence of DNA methylation and demethylation is associated with transcription regulation. Nat Commun. 2021 09 06; 12(1):5285.
    View in: PubMed
    Score: 0.111
  20. Maternal folate genes and aberrant DNA hypermethylation in pediatric acute lymphoblastic leukemia. PLoS One. 2018; 13(5):e0197408.
    View in: PubMed
    Score: 0.089
  21. Regulation of AURKC expression by CpG island methylation in human cancer cells. Tumour Biol. 2015 Sep; 36(10):8147-58.
    View in: PubMed
    Score: 0.072
  22. Comparison and quantitative verification of mapping algorithms for whole-genome bisulfite sequencing. Nucleic Acids Res. 2014 Apr; 42(6):e43.
    View in: PubMed
    Score: 0.065
  23. Repetitive elements and enforced transcriptional repression co-operate to enhance DNA methylation spreading into a promoter CpG-island. Nucleic Acids Res. 2012 Aug; 40(15):7257-68.
    View in: PubMed
    Score: 0.058
  24. Effects of TET2 mutations on DNA methylation in chronic myelomonocytic leukemia. Epigenetics. 2012 Feb; 7(2):201-7.
    View in: PubMed
    Score: 0.057
  25. DNA methylation profiles of primary colorectal carcinoma and matched liver metastasis. PLoS One. 2011; 6(11):e27889.
    View in: PubMed
    Score: 0.056
  26. Association between folate levels and CpG Island hypermethylation in normal colorectal mucosa. Cancer Prev Res (Phila). 2010 Dec; 3(12):1552-64.
    View in: PubMed
    Score: 0.053
  27. Characteristic methylation profile in CpG island methylator phenotype-negative distal colorectal cancers. Int J Cancer. 2010 Nov 01; 127(9):2095-105.
    View in: PubMed
    Score: 0.052
  28. Genome architecture marked by retrotransposons modulates predisposition to DNA methylation in cancer. Genome Res. 2010 Oct; 20(10):1369-82.
    View in: PubMed
    Score: 0.052
  29. Epigenetic maturation in colonic mucosa continues beyond infancy in mice. Hum Mol Genet. 2010 Jun 01; 19(11):2168-76.
    View in: PubMed
    Score: 0.050
  30. Widespread and tissue specific age-related DNA methylation changes in mice. Genome Res. 2010 Mar; 20(3):332-40.
    View in: PubMed
    Score: 0.050
  31. Concordant DNA methylation in synchronous colorectal carcinomas. Cancer Prev Res (Phila). 2009 Sep; 2(9):814-22.
    View in: PubMed
    Score: 0.048
  32. IGFBP7 is a p53-responsive gene specifically silenced in colorectal cancer with CpG island methylator phenotype. Carcinogenesis. 2010 Mar; 31(3):342-9.
    View in: PubMed
    Score: 0.048
  33. CpG island methylation profiling in human melanoma cell lines. Melanoma Res. 2009 Jun; 19(3):146-55.
    View in: PubMed
    Score: 0.048
  34. Sensitive and specific detection of early gastric cancer with DNA methylation analysis of gastric washes. Gastroenterology. 2009 Jun; 136(7):2149-58.
    View in: PubMed
    Score: 0.047
  35. Global DNA hypomethylation (LINE-1) in the normal colon and lifestyle characteristics and dietary and genetic factors. Cancer Epidemiol Biomarkers Prev. 2009 Apr; 18(4):1041-9.
    View in: PubMed
    Score: 0.047
  36. Hypomethylation of long interspersed nuclear element-1 in hepatocellular carcinomas. Mod Pathol. 2009 Mar; 22(3):442-9.
    View in: PubMed
    Score: 0.046
  37. An Sp1/Sp3 binding polymorphism confers methylation protection. PLoS Genet. 2008 Aug 22; 4(8):e1000162.
    View in: PubMed
    Score: 0.045
  38. Variable DNA methylation patterns associated with progression of disease in hepatocellular carcinomas. Carcinogenesis. 2008 Oct; 29(10):1901-10.
    View in: PubMed
    Score: 0.045
  39. Aberrant CpG island methylation in acute myeloid leukemia is accentuated at relapse. Blood. 2008 Aug 15; 112(4):1366-73.
    View in: PubMed
    Score: 0.044
  40. Gene silencing in cancer by histone H3 lysine 27 trimethylation independent of promoter DNA methylation. Nat Genet. 2008 Jun; 40(6):741-50.
    View in: PubMed
    Score: 0.044
  41. Epigenetic-genetic interactions in the APC/WNT, RAS/RAF, and P53 pathways in colorectal carcinoma. Clin Cancer Res. 2008 May 01; 14(9):2560-9.
    View in: PubMed
    Score: 0.044
  42. Identification of novel tumor markers in prostate, colon and breast cancer by unbiased methylation profiling. PLoS One. 2008 Apr 30; 3(4):e2079.
    View in: PubMed
    Score: 0.044
  43. Induction of hypomethylation and molecular response after decitabine therapy in patients with chronic myelomonocytic leukemia. Blood. 2008 Feb 15; 111(4):2382-4.
    View in: PubMed
    Score: 0.043
  44. Delta DNMT3B variants regulate DNA methylation in a promoter-specific manner. Cancer Res. 2007 Nov 15; 67(22):10647-52.
    View in: PubMed
    Score: 0.043
  45. Integrated genetic and epigenetic analysis identifies three different subclasses of colon cancer. Proc Natl Acad Sci U S A. 2007 Nov 20; 104(47):18654-9.
    View in: PubMed
    Score: 0.043
  46. High-throughput methylation profiling by MCA coupled to CpG island microarray. Genome Res. 2007 Oct; 17(10):1529-36.
    View in: PubMed
    Score: 0.042
  47. Age-related DNA methylation changes in normal human prostate tissues. Clin Cancer Res. 2007 Jul 01; 13(13):3796-802.
    View in: PubMed
    Score: 0.042
  48. LINE-1 hypomethylation in cancer is highly variable and inversely correlated with microsatellite instability. PLoS One. 2007 May 02; 2(5):e399.
    View in: PubMed
    Score: 0.041
  49. RIL, a LIM gene on 5q31, is silenced by methylation in cancer and sensitizes cancer cells to apoptosis. Cancer Res. 2007 Mar 01; 67(5):1997-2005.
    View in: PubMed
    Score: 0.041
  50. Rare CpG island methylator phenotype in ulcerative colitis-associated neoplasias. Gastroenterology. 2007 Apr; 132(4):1254-60.
    View in: PubMed
    Score: 0.040
  51. Correlation between CpG methylation profiles and hormone receptor status in breast cancers. Breast Cancer Res. 2007; 9(4):R57.
    View in: PubMed
    Score: 0.040
  52. Epigenetic inactivation of EGFR by CpG island hypermethylation in cancer. Cancer Biol Ther. 2006 Nov; 5(11):1494-501.
    View in: PubMed
    Score: 0.040
  53. Silencing of bidirectional promoters by DNA methylation in tumorigenesis. Cancer Res. 2006 May 15; 66(10):5077-84.
    View in: PubMed
    Score: 0.039
  54. DNA methylation changes after 5-aza-2'-deoxycytidine therapy in patients with leukemia. Cancer Res. 2006 May 15; 66(10):5495-503.
    View in: PubMed
    Score: 0.039
  55. CIMP, at last. Gastroenterology. 2005 Sep; 129(3):1121-4.
    View in: PubMed
    Score: 0.037
  56. Phenotype of microsatellite-stable colorectal carcinomas with CpG island methylation. Am J Surg Pathol. 2005 Apr; 29(4):429-36.
    View in: PubMed
    Score: 0.036
  57. Chromatin immunoprecipitation microarrays for identification of genes silenced by histone H3 lysine 9 methylation. Proc Natl Acad Sci U S A. 2004 May 11; 101(19):7398-403.
    View in: PubMed
    Score: 0.033
  58. Major epigenetic development distinguishing neuronal and non-neuronal cells occurs postnatally in the murine hypothalamus. Hum Mol Genet. 2014 Mar 15; 23(6):1579-90.
    View in: PubMed
    Score: 0.016
  59. Frequent alteration of MLL3 frameshift mutations in microsatellite deficient colorectal cancer. PLoS One. 2011; 6(8):e23320.
    View in: PubMed
    Score: 0.014
  60. Season of conception in rural gambia affects DNA methylation at putative human metastable epialleles. PLoS Genet. 2010 Dec 23; 6(12):e1001252.
    View in: PubMed
    Score: 0.013
  61. Foxa1 functions as a pioneer transcription factor at transposable elements to activate Afp during differentiation of embryonic stem cells. J Biol Chem. 2010 May 21; 285(21):16135-44.
    View in: PubMed
    Score: 0.013
  62. Epigenetic profiles distinguish malignant pleural mesothelioma from lung adenocarcinoma. Cancer Res. 2009 Dec 01; 69(23):9073-82.
    View in: PubMed
    Score: 0.012
  63. 15-Lipoxygenase-1 transcriptional silencing by DNA methyltransferase-1 independently of DNA methylation. FASEB J. 2008 Jun; 22(6):1981-92.
    View in: PubMed
    Score: 0.011
  64. Decitabine improves patient outcomes in myelodysplastic syndromes: results of a phase III randomized study. Cancer. 2006 Apr 15; 106(8):1794-803.
    View in: PubMed
    Score: 0.010
  65. Critical role of histone methylation in tumor suppressor gene silencing in colorectal cancer. Mol Cell Biol. 2003 Jan; 23(1):206-15.
    View in: PubMed
    Score: 0.008
  66. HLTF gene silencing in human colon cancer. Proc Natl Acad Sci U S A. 2002 Apr 02; 99(7):4562-7.
    View in: PubMed
    Score: 0.007
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Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.