Connection

LANLAN SHEN to DNA Methylation

This is a "connection" page, showing publications LANLAN SHEN has written about DNA Methylation.
Connection Strength

5.066
  1. Postnatal epigenetic regulation of intestinal stem cells requires DNA methylation and is guided by the microbiome. Genome Biol. 2015 Sep 30; 16:211.
    View in: PubMed
    Score: 0.319
  2. Developmentally programmed 3' CpG island methylation confers tissue- and cell-type-specific transcriptional activation. Mol Cell Biol. 2013 May; 33(9):1845-58.
    View in: PubMed
    Score: 0.267
  3. DNA methylation predicts survival and response to therapy in patients with myelodysplastic syndromes. J Clin Oncol. 2010 Feb 01; 28(4):605-13.
    View in: PubMed
    Score: 0.214
  4. Epigenomic profiling indicates a role for DNA methylation in early postnatal liver development. Hum Mol Genet. 2009 Aug 15; 18(16):3026-38.
    View in: PubMed
    Score: 0.205
  5. Drug sensitivity prediction by CpG island methylation profile in the NCI-60 cancer cell line panel. Cancer Res. 2007 Dec 01; 67(23):11335-43.
    View in: PubMed
    Score: 0.186
  6. Association between DNA methylation and shortened survival in patients with advanced colorectal cancer treated with 5-fluorouracil based chemotherapy. Clin Cancer Res. 2007 Oct 15; 13(20):6093-8.
    View in: PubMed
    Score: 0.184
  7. Genome-wide profiling of DNA methylation reveals a class of normally methylated CpG island promoters. PLoS Genet. 2007 Oct; 3(10):2023-36.
    View in: PubMed
    Score: 0.183
  8. Methods of DNA methylation analysis. Curr Opin Clin Nutr Metab Care. 2007 Sep; 10(5):576-81.
    View in: PubMed
    Score: 0.182
  9. Optimizing annealing temperature overcomes bias in bisulfite PCR methylation analysis. Biotechniques. 2007 Jan; 42(1):48, 50, 52 passim.
    View in: PubMed
    Score: 0.174
  10. MGMT promoter methylation and field defect in sporadic colorectal cancer. J Natl Cancer Inst. 2005 Sep 21; 97(18):1330-8.
    View in: PubMed
    Score: 0.159
  11. The DNA methylome of pediatric brain tumors appears shaped by structural variation and predicts survival. Nat Commun. 2024 Aug 08; 15(1):6775.
    View in: PubMed
    Score: 0.148
  12. Functional characterization of age-dependent p16 epimutation reveals biological drivers and therapeutic targets for colorectal cancer. J Exp Clin Cancer Res. 2023 May 04; 42(1):113.
    View in: PubMed
    Score: 0.135
  13. P14 methylation in human colon cancer is associated with microsatellite instability and wild-type p53. Gastroenterology. 2003 Mar; 124(3):626-33.
    View in: PubMed
    Score: 0.134
  14. Aberrant DNA methylation of p57KIP2 identifies a cell-cycle regulatory pathway with prognostic impact in adult acute lymphocytic leukemia. Blood. 2003 May 15; 101(10):4131-6.
    View in: PubMed
    Score: 0.133
  15. Lack of p21(CIP1) DNA methylation in acute lymphocytic leukemia. Blood. 2002 Nov 01; 100(9):3432-3; author reply 3433-4.
    View in: PubMed
    Score: 0.131
  16. DNA methylation and environmental exposures in human hepatocellular carcinoma. J Natl Cancer Inst. 2002 May 15; 94(10):755-61.
    View in: PubMed
    Score: 0.126
  17. The concurrence of DNA methylation and demethylation is associated with transcription regulation. Nat Commun. 2021 09 06; 12(1):5285.
    View in: PubMed
    Score: 0.120
  18. Maternal folate genes and aberrant DNA hypermethylation in pediatric acute lymphoblastic leukemia. PLoS One. 2018; 13(5):e0197408.
    View in: PubMed
    Score: 0.096
  19. Regulation of AURKC expression by CpG island methylation in human cancer cells. Tumour Biol. 2015 Sep; 36(10):8147-58.
    View in: PubMed
    Score: 0.078
  20. Comparison and quantitative verification of mapping algorithms for whole-genome bisulfite sequencing. Nucleic Acids Res. 2014 Apr; 42(6):e43.
    View in: PubMed
    Score: 0.071
  21. Repetitive elements and enforced transcriptional repression co-operate to enhance DNA methylation spreading into a promoter CpG-island. Nucleic Acids Res. 2012 Aug; 40(15):7257-68.
    View in: PubMed
    Score: 0.063
  22. Effects of TET2 mutations on DNA methylation in chronic myelomonocytic leukemia. Epigenetics. 2012 Feb; 7(2):201-7.
    View in: PubMed
    Score: 0.062
  23. DNA methylation profiles of primary colorectal carcinoma and matched liver metastasis. PLoS One. 2011; 6(11):e27889.
    View in: PubMed
    Score: 0.061
  24. Association between folate levels and CpG Island hypermethylation in normal colorectal mucosa. Cancer Prev Res (Phila). 2010 Dec; 3(12):1552-64.
    View in: PubMed
    Score: 0.057
  25. Characteristic methylation profile in CpG island methylator phenotype-negative distal colorectal cancers. Int J Cancer. 2010 Nov 01; 127(9):2095-105.
    View in: PubMed
    Score: 0.057
  26. Genome architecture marked by retrotransposons modulates predisposition to DNA methylation in cancer. Genome Res. 2010 Oct; 20(10):1369-82.
    View in: PubMed
    Score: 0.056
  27. Epigenetic maturation in colonic mucosa continues beyond infancy in mice. Hum Mol Genet. 2010 Jun 01; 19(11):2168-76.
    View in: PubMed
    Score: 0.054
  28. Widespread and tissue specific age-related DNA methylation changes in mice. Genome Res. 2010 Mar; 20(3):332-40.
    View in: PubMed
    Score: 0.054
  29. Concordant DNA methylation in synchronous colorectal carcinomas. Cancer Prev Res (Phila). 2009 Sep; 2(9):814-22.
    View in: PubMed
    Score: 0.052
  30. IGFBP7 is a p53-responsive gene specifically silenced in colorectal cancer with CpG island methylator phenotype. Carcinogenesis. 2010 Mar; 31(3):342-9.
    View in: PubMed
    Score: 0.052
  31. CpG island methylation profiling in human melanoma cell lines. Melanoma Res. 2009 Jun; 19(3):146-55.
    View in: PubMed
    Score: 0.051
  32. Sensitive and specific detection of early gastric cancer with DNA methylation analysis of gastric washes. Gastroenterology. 2009 Jun; 136(7):2149-58.
    View in: PubMed
    Score: 0.051
  33. Global DNA hypomethylation (LINE-1) in the normal colon and lifestyle characteristics and dietary and genetic factors. Cancer Epidemiol Biomarkers Prev. 2009 Apr; 18(4):1041-9.
    View in: PubMed
    Score: 0.051
  34. Hypomethylation of long interspersed nuclear element-1 in hepatocellular carcinomas. Mod Pathol. 2009 Mar; 22(3):442-9.
    View in: PubMed
    Score: 0.050
  35. An Sp1/Sp3 binding polymorphism confers methylation protection. PLoS Genet. 2008 Aug 22; 4(8):e1000162.
    View in: PubMed
    Score: 0.049
  36. Variable DNA methylation patterns associated with progression of disease in hepatocellular carcinomas. Carcinogenesis. 2008 Oct; 29(10):1901-10.
    View in: PubMed
    Score: 0.048
  37. Aberrant CpG island methylation in acute myeloid leukemia is accentuated at relapse. Blood. 2008 Aug 15; 112(4):1366-73.
    View in: PubMed
    Score: 0.048
  38. Gene silencing in cancer by histone H3 lysine 27 trimethylation independent of promoter DNA methylation. Nat Genet. 2008 Jun; 40(6):741-50.
    View in: PubMed
    Score: 0.048
  39. Epigenetic-genetic interactions in the APC/WNT, RAS/RAF, and P53 pathways in colorectal carcinoma. Clin Cancer Res. 2008 May 01; 14(9):2560-9.
    View in: PubMed
    Score: 0.048
  40. Identification of novel tumor markers in prostate, colon and breast cancer by unbiased methylation profiling. PLoS One. 2008 Apr 30; 3(4):e2079.
    View in: PubMed
    Score: 0.048
  41. Induction of hypomethylation and molecular response after decitabine therapy in patients with chronic myelomonocytic leukemia. Blood. 2008 Feb 15; 111(4):2382-4.
    View in: PubMed
    Score: 0.046
  42. Delta DNMT3B variants regulate DNA methylation in a promoter-specific manner. Cancer Res. 2007 Nov 15; 67(22):10647-52.
    View in: PubMed
    Score: 0.046
  43. Integrated genetic and epigenetic analysis identifies three different subclasses of colon cancer. Proc Natl Acad Sci U S A. 2007 Nov 20; 104(47):18654-9.
    View in: PubMed
    Score: 0.046
  44. High-throughput methylation profiling by MCA coupled to CpG island microarray. Genome Res. 2007 Oct; 17(10):1529-36.
    View in: PubMed
    Score: 0.046
  45. Age-related DNA methylation changes in normal human prostate tissues. Clin Cancer Res. 2007 Jul 01; 13(13):3796-802.
    View in: PubMed
    Score: 0.045
  46. LINE-1 hypomethylation in cancer is highly variable and inversely correlated with microsatellite instability. PLoS One. 2007 May 02; 2(5):e399.
    View in: PubMed
    Score: 0.045
  47. RIL, a LIM gene on 5q31, is silenced by methylation in cancer and sensitizes cancer cells to apoptosis. Cancer Res. 2007 Mar 01; 67(5):1997-2005.
    View in: PubMed
    Score: 0.044
  48. Rare CpG island methylator phenotype in ulcerative colitis-associated neoplasias. Gastroenterology. 2007 Apr; 132(4):1254-60.
    View in: PubMed
    Score: 0.044
  49. Correlation between CpG methylation profiles and hormone receptor status in breast cancers. Breast Cancer Res. 2007; 9(4):R57.
    View in: PubMed
    Score: 0.044
  50. Epigenetic inactivation of EGFR by CpG island hypermethylation in cancer. Cancer Biol Ther. 2006 Nov; 5(11):1494-501.
    View in: PubMed
    Score: 0.043
  51. Silencing of bidirectional promoters by DNA methylation in tumorigenesis. Cancer Res. 2006 May 15; 66(10):5077-84.
    View in: PubMed
    Score: 0.042
  52. DNA methylation changes after 5-aza-2'-deoxycytidine therapy in patients with leukemia. Cancer Res. 2006 May 15; 66(10):5495-503.
    View in: PubMed
    Score: 0.042
  53. CIMP, at last. Gastroenterology. 2005 Sep; 129(3):1121-4.
    View in: PubMed
    Score: 0.040
  54. Phenotype of microsatellite-stable colorectal carcinomas with CpG island methylation. Am J Surg Pathol. 2005 Apr; 29(4):429-36.
    View in: PubMed
    Score: 0.039
  55. Chromatin immunoprecipitation microarrays for identification of genes silenced by histone H3 lysine 9 methylation. Proc Natl Acad Sci U S A. 2004 May 11; 101(19):7398-403.
    View in: PubMed
    Score: 0.036
  56. Major epigenetic development distinguishing neuronal and non-neuronal cells occurs postnatally in the murine hypothalamus. Hum Mol Genet. 2014 Mar 15; 23(6):1579-90.
    View in: PubMed
    Score: 0.017
  57. Frequent alteration of MLL3 frameshift mutations in microsatellite deficient colorectal cancer. PLoS One. 2011; 6(8):e23320.
    View in: PubMed
    Score: 0.015
  58. Season of conception in rural gambia affects DNA methylation at putative human metastable epialleles. PLoS Genet. 2010 Dec 23; 6(12):e1001252.
    View in: PubMed
    Score: 0.014
  59. Foxa1 functions as a pioneer transcription factor at transposable elements to activate Afp during differentiation of embryonic stem cells. J Biol Chem. 2010 May 21; 285(21):16135-44.
    View in: PubMed
    Score: 0.014
  60. Epigenetic profiles distinguish malignant pleural mesothelioma from lung adenocarcinoma. Cancer Res. 2009 Dec 01; 69(23):9073-82.
    View in: PubMed
    Score: 0.013
  61. 15-Lipoxygenase-1 transcriptional silencing by DNA methyltransferase-1 independently of DNA methylation. FASEB J. 2008 Jun; 22(6):1981-92.
    View in: PubMed
    Score: 0.012
  62. Decitabine improves patient outcomes in myelodysplastic syndromes: results of a phase III randomized study. Cancer. 2006 Apr 15; 106(8):1794-803.
    View in: PubMed
    Score: 0.010
  63. Critical role of histone methylation in tumor suppressor gene silencing in colorectal cancer. Mol Cell Biol. 2003 Jan; 23(1):206-15.
    View in: PubMed
    Score: 0.008
  64. HLTF gene silencing in human colon cancer. Proc Natl Acad Sci U S A. 2002 Apr 02; 99(7):4562-7.
    View in: PubMed
    Score: 0.008
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.