LANLAN SHEN to DNA Methylation
This is a "connection" page, showing publications LANLAN SHEN has written about DNA Methylation.
Connection Strength
5.066
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Postnatal epigenetic regulation of intestinal stem cells requires DNA methylation and is guided by the microbiome. Genome Biol. 2015 Sep 30; 16:211.
Score: 0.319
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Developmentally programmed 3' CpG island methylation confers tissue- and cell-type-specific transcriptional activation. Mol Cell Biol. 2013 May; 33(9):1845-58.
Score: 0.267
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DNA methylation predicts survival and response to therapy in patients with myelodysplastic syndromes. J Clin Oncol. 2010 Feb 01; 28(4):605-13.
Score: 0.214
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Epigenomic profiling indicates a role for DNA methylation in early postnatal liver development. Hum Mol Genet. 2009 Aug 15; 18(16):3026-38.
Score: 0.205
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Drug sensitivity prediction by CpG island methylation profile in the NCI-60 cancer cell line panel. Cancer Res. 2007 Dec 01; 67(23):11335-43.
Score: 0.186
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Association between DNA methylation and shortened survival in patients with advanced colorectal cancer treated with 5-fluorouracil based chemotherapy. Clin Cancer Res. 2007 Oct 15; 13(20):6093-8.
Score: 0.184
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Genome-wide profiling of DNA methylation reveals a class of normally methylated CpG island promoters. PLoS Genet. 2007 Oct; 3(10):2023-36.
Score: 0.183
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Methods of DNA methylation analysis. Curr Opin Clin Nutr Metab Care. 2007 Sep; 10(5):576-81.
Score: 0.182
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Optimizing annealing temperature overcomes bias in bisulfite PCR methylation analysis. Biotechniques. 2007 Jan; 42(1):48, 50, 52 passim.
Score: 0.174
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MGMT promoter methylation and field defect in sporadic colorectal cancer. J Natl Cancer Inst. 2005 Sep 21; 97(18):1330-8.
Score: 0.159
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The DNA methylome of pediatric brain tumors appears shaped by structural variation and predicts survival. Nat Commun. 2024 Aug 08; 15(1):6775.
Score: 0.148
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Functional characterization of age-dependent p16 epimutation reveals biological drivers and therapeutic targets for colorectal cancer. J Exp Clin Cancer Res. 2023 May 04; 42(1):113.
Score: 0.135
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P14 methylation in human colon cancer is associated with microsatellite instability and wild-type p53. Gastroenterology. 2003 Mar; 124(3):626-33.
Score: 0.134
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Aberrant DNA methylation of p57KIP2 identifies a cell-cycle regulatory pathway with prognostic impact in adult acute lymphocytic leukemia. Blood. 2003 May 15; 101(10):4131-6.
Score: 0.133
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Lack of p21(CIP1) DNA methylation in acute lymphocytic leukemia. Blood. 2002 Nov 01; 100(9):3432-3; author reply 3433-4.
Score: 0.131
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DNA methylation and environmental exposures in human hepatocellular carcinoma. J Natl Cancer Inst. 2002 May 15; 94(10):755-61.
Score: 0.126
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The concurrence of DNA methylation and demethylation is associated with transcription regulation. Nat Commun. 2021 09 06; 12(1):5285.
Score: 0.120
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Maternal folate genes and aberrant DNA hypermethylation in pediatric acute lymphoblastic leukemia. PLoS One. 2018; 13(5):e0197408.
Score: 0.096
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Regulation of AURKC expression by CpG island methylation in human cancer cells. Tumour Biol. 2015 Sep; 36(10):8147-58.
Score: 0.078
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Comparison and quantitative verification of mapping algorithms for whole-genome bisulfite sequencing. Nucleic Acids Res. 2014 Apr; 42(6):e43.
Score: 0.071
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Repetitive elements and enforced transcriptional repression co-operate to enhance DNA methylation spreading into a promoter CpG-island. Nucleic Acids Res. 2012 Aug; 40(15):7257-68.
Score: 0.063
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Effects of TET2 mutations on DNA methylation in chronic myelomonocytic leukemia. Epigenetics. 2012 Feb; 7(2):201-7.
Score: 0.062
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DNA methylation profiles of primary colorectal carcinoma and matched liver metastasis. PLoS One. 2011; 6(11):e27889.
Score: 0.061
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Association between folate levels and CpG Island hypermethylation in normal colorectal mucosa. Cancer Prev Res (Phila). 2010 Dec; 3(12):1552-64.
Score: 0.057
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Characteristic methylation profile in CpG island methylator phenotype-negative distal colorectal cancers. Int J Cancer. 2010 Nov 01; 127(9):2095-105.
Score: 0.057
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Genome architecture marked by retrotransposons modulates predisposition to DNA methylation in cancer. Genome Res. 2010 Oct; 20(10):1369-82.
Score: 0.056
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Epigenetic maturation in colonic mucosa continues beyond infancy in mice. Hum Mol Genet. 2010 Jun 01; 19(11):2168-76.
Score: 0.054
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Widespread and tissue specific age-related DNA methylation changes in mice. Genome Res. 2010 Mar; 20(3):332-40.
Score: 0.054
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Concordant DNA methylation in synchronous colorectal carcinomas. Cancer Prev Res (Phila). 2009 Sep; 2(9):814-22.
Score: 0.052
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IGFBP7 is a p53-responsive gene specifically silenced in colorectal cancer with CpG island methylator phenotype. Carcinogenesis. 2010 Mar; 31(3):342-9.
Score: 0.052
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CpG island methylation profiling in human melanoma cell lines. Melanoma Res. 2009 Jun; 19(3):146-55.
Score: 0.051
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Sensitive and specific detection of early gastric cancer with DNA methylation analysis of gastric washes. Gastroenterology. 2009 Jun; 136(7):2149-58.
Score: 0.051
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Global DNA hypomethylation (LINE-1) in the normal colon and lifestyle characteristics and dietary and genetic factors. Cancer Epidemiol Biomarkers Prev. 2009 Apr; 18(4):1041-9.
Score: 0.051
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Hypomethylation of long interspersed nuclear element-1 in hepatocellular carcinomas. Mod Pathol. 2009 Mar; 22(3):442-9.
Score: 0.050
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An Sp1/Sp3 binding polymorphism confers methylation protection. PLoS Genet. 2008 Aug 22; 4(8):e1000162.
Score: 0.049
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Variable DNA methylation patterns associated with progression of disease in hepatocellular carcinomas. Carcinogenesis. 2008 Oct; 29(10):1901-10.
Score: 0.048
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Aberrant CpG island methylation in acute myeloid leukemia is accentuated at relapse. Blood. 2008 Aug 15; 112(4):1366-73.
Score: 0.048
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Gene silencing in cancer by histone H3 lysine 27 trimethylation independent of promoter DNA methylation. Nat Genet. 2008 Jun; 40(6):741-50.
Score: 0.048
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Epigenetic-genetic interactions in the APC/WNT, RAS/RAF, and P53 pathways in colorectal carcinoma. Clin Cancer Res. 2008 May 01; 14(9):2560-9.
Score: 0.048
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Identification of novel tumor markers in prostate, colon and breast cancer by unbiased methylation profiling. PLoS One. 2008 Apr 30; 3(4):e2079.
Score: 0.048
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Induction of hypomethylation and molecular response after decitabine therapy in patients with chronic myelomonocytic leukemia. Blood. 2008 Feb 15; 111(4):2382-4.
Score: 0.046
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Delta DNMT3B variants regulate DNA methylation in a promoter-specific manner. Cancer Res. 2007 Nov 15; 67(22):10647-52.
Score: 0.046
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Integrated genetic and epigenetic analysis identifies three different subclasses of colon cancer. Proc Natl Acad Sci U S A. 2007 Nov 20; 104(47):18654-9.
Score: 0.046
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High-throughput methylation profiling by MCA coupled to CpG island microarray. Genome Res. 2007 Oct; 17(10):1529-36.
Score: 0.046
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Age-related DNA methylation changes in normal human prostate tissues. Clin Cancer Res. 2007 Jul 01; 13(13):3796-802.
Score: 0.045
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LINE-1 hypomethylation in cancer is highly variable and inversely correlated with microsatellite instability. PLoS One. 2007 May 02; 2(5):e399.
Score: 0.045
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RIL, a LIM gene on 5q31, is silenced by methylation in cancer and sensitizes cancer cells to apoptosis. Cancer Res. 2007 Mar 01; 67(5):1997-2005.
Score: 0.044
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Rare CpG island methylator phenotype in ulcerative colitis-associated neoplasias. Gastroenterology. 2007 Apr; 132(4):1254-60.
Score: 0.044
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Correlation between CpG methylation profiles and hormone receptor status in breast cancers. Breast Cancer Res. 2007; 9(4):R57.
Score: 0.044
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Epigenetic inactivation of EGFR by CpG island hypermethylation in cancer. Cancer Biol Ther. 2006 Nov; 5(11):1494-501.
Score: 0.043
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Silencing of bidirectional promoters by DNA methylation in tumorigenesis. Cancer Res. 2006 May 15; 66(10):5077-84.
Score: 0.042
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DNA methylation changes after 5-aza-2'-deoxycytidine therapy in patients with leukemia. Cancer Res. 2006 May 15; 66(10):5495-503.
Score: 0.042
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CIMP, at last. Gastroenterology. 2005 Sep; 129(3):1121-4.
Score: 0.040
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Phenotype of microsatellite-stable colorectal carcinomas with CpG island methylation. Am J Surg Pathol. 2005 Apr; 29(4):429-36.
Score: 0.039
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Chromatin immunoprecipitation microarrays for identification of genes silenced by histone H3 lysine 9 methylation. Proc Natl Acad Sci U S A. 2004 May 11; 101(19):7398-403.
Score: 0.036
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Major epigenetic development distinguishing neuronal and non-neuronal cells occurs postnatally in the murine hypothalamus. Hum Mol Genet. 2014 Mar 15; 23(6):1579-90.
Score: 0.017
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Frequent alteration of MLL3 frameshift mutations in microsatellite deficient colorectal cancer. PLoS One. 2011; 6(8):e23320.
Score: 0.015
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Season of conception in rural gambia affects DNA methylation at putative human metastable epialleles. PLoS Genet. 2010 Dec 23; 6(12):e1001252.
Score: 0.014
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Foxa1 functions as a pioneer transcription factor at transposable elements to activate Afp during differentiation of embryonic stem cells. J Biol Chem. 2010 May 21; 285(21):16135-44.
Score: 0.014
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Epigenetic profiles distinguish malignant pleural mesothelioma from lung adenocarcinoma. Cancer Res. 2009 Dec 01; 69(23):9073-82.
Score: 0.013
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15-Lipoxygenase-1 transcriptional silencing by DNA methyltransferase-1 independently of DNA methylation. FASEB J. 2008 Jun; 22(6):1981-92.
Score: 0.012
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Decitabine improves patient outcomes in myelodysplastic syndromes: results of a phase III randomized study. Cancer. 2006 Apr 15; 106(8):1794-803.
Score: 0.010
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Critical role of histone methylation in tumor suppressor gene silencing in colorectal cancer. Mol Cell Biol. 2003 Jan; 23(1):206-15.
Score: 0.008
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HLTF gene silencing in human colon cancer. Proc Natl Acad Sci U S A. 2002 Apr 02; 99(7):4562-7.
Score: 0.008