Connection

LANLAN SHEN to Humans

This is a "connection" page, showing publications LANLAN SHEN has written about Humans.
Connection Strength

0.299
  1. DNA methylation profiling at base-pair resolution reveals unique epigenetic features of early-onset colorectal cancer in underrepresented populations. Clin Epigenetics. 2025 Jan 22; 17(1):11.
    View in: PubMed
    Score: 0.025
  2. Dietary Folate and Cofactors Accelerate Age-dependent p16 Epimutation to Promote Intestinal Tumorigenesis. Cancer Res Commun. 2024 01 19; 4(1):164-169.
    View in: PubMed
    Score: 0.023
  3. Functional characterization of age-dependent p16 epimutation reveals biological drivers and therapeutic targets for colorectal cancer. J Exp Clin Cancer Res. 2023 May 04; 42(1):113.
    View in: PubMed
    Score: 0.022
  4. Epigenome - A mediator for host-microbiome crosstalk. Semin Perinatol. 2021 10; 45(6):151455.
    View in: PubMed
    Score: 0.019
  5. Developmentally programmed 3' CpG island methylation confers tissue- and cell-type-specific transcriptional activation. Mol Cell Biol. 2013 May; 33(9):1845-58.
    View in: PubMed
    Score: 0.011
  6. DNA methylation predicts survival and response to therapy in patients with myelodysplastic syndromes. J Clin Oncol. 2010 Feb 01; 28(4):605-13.
    View in: PubMed
    Score: 0.009
  7. Drug sensitivity prediction by CpG island methylation profile in the NCI-60 cancer cell line panel. Cancer Res. 2007 Dec 01; 67(23):11335-43.
    View in: PubMed
    Score: 0.007
  8. Integrated genetic and epigenetic analysis identifies three different subclasses of colon cancer. Proc Natl Acad Sci U S A. 2007 Nov 20; 104(47):18654-9.
    View in: PubMed
    Score: 0.007
  9. Association between DNA methylation and shortened survival in patients with advanced colorectal cancer treated with 5-fluorouracil based chemotherapy. Clin Cancer Res. 2007 Oct 15; 13(20):6093-8.
    View in: PubMed
    Score: 0.007
  10. Genome-wide profiling of DNA methylation reveals a class of normally methylated CpG island promoters. PLoS Genet. 2007 Oct; 3(10):2023-36.
    View in: PubMed
    Score: 0.007
  11. Methods of DNA methylation analysis. Curr Opin Clin Nutr Metab Care. 2007 Sep; 10(5):576-81.
    View in: PubMed
    Score: 0.007
  12. MGMT promoter methylation and field defect in sporadic colorectal cancer. J Natl Cancer Inst. 2005 Sep 21; 97(18):1330-8.
    View in: PubMed
    Score: 0.006
  13. Global DNA methylation differences involving germline structural variation impact gene expression in pediatric brain tumors. Nat Commun. 2025 May 21; 16(1):4713.
    View in: PubMed
    Score: 0.006
  14. The DNA methylome of pediatric brain tumors appears shaped by structural variation and predicts survival. Nat Commun. 2024 Aug 08; 15(1):6775.
    View in: PubMed
    Score: 0.006
  15. P14 methylation in human colon cancer is associated with microsatellite instability and wild-type p53. Gastroenterology. 2003 Mar; 124(3):626-33.
    View in: PubMed
    Score: 0.005
  16. Aberrant DNA methylation of p57KIP2 identifies a cell-cycle regulatory pathway with prognostic impact in adult acute lymphocytic leukemia. Blood. 2003 May 15; 101(10):4131-6.
    View in: PubMed
    Score: 0.005
  17. Lack of p21(CIP1) DNA methylation in acute lymphocytic leukemia. Blood. 2002 Nov 01; 100(9):3432-3; author reply 3433-4.
    View in: PubMed
    Score: 0.005
  18. DNA methylation and environmental exposures in human hepatocellular carcinoma. J Natl Cancer Inst. 2002 May 15; 94(10):755-61.
    View in: PubMed
    Score: 0.005
  19. The concurrence of DNA methylation and demethylation is associated with transcription regulation. Nat Commun. 2021 09 06; 12(1):5285.
    View in: PubMed
    Score: 0.005
  20. Predict multicategory causes of death in lung cancer patients using clinicopathologic factors. Comput Biol Med. 2021 02; 129:104161.
    View in: PubMed
    Score: 0.005
  21. Study of Environmental Enteropathy and Malnutrition (SEEM) in Pakistan: protocols for biopsy based biomarker discovery and validation. BMC Pediatr. 2019 07 22; 19(1):247.
    View in: PubMed
    Score: 0.004
  22. Maternal folate genes and aberrant DNA hypermethylation in pediatric acute lymphoblastic leukemia. PLoS One. 2018; 13(5):e0197408.
    View in: PubMed
    Score: 0.004
  23. Regulation of AURKC expression by CpG island methylation in human cancer cells. Tumour Biol. 2015 Sep; 36(10):8147-58.
    View in: PubMed
    Score: 0.003
  24. CDC42 inhibition suppresses progression of incipient intestinal tumors. Cancer Res. 2014 Oct 01; 74(19):5480-92.
    View in: PubMed
    Score: 0.003
  25. Comparison and quantitative verification of mapping algorithms for whole-genome bisulfite sequencing. Nucleic Acids Res. 2014 Apr; 42(6):e43.
    View in: PubMed
    Score: 0.003
  26. Repetitive elements and enforced transcriptional repression co-operate to enhance DNA methylation spreading into a promoter CpG-island. Nucleic Acids Res. 2012 Aug; 40(15):7257-68.
    View in: PubMed
    Score: 0.003
  27. Effects of TET2 mutations on DNA methylation in chronic myelomonocytic leukemia. Epigenetics. 2012 Feb; 7(2):201-7.
    View in: PubMed
    Score: 0.003
  28. DNA methylation profiles of primary colorectal carcinoma and matched liver metastasis. PLoS One. 2011; 6(11):e27889.
    View in: PubMed
    Score: 0.002
  29. Frequent alteration of MLL3 frameshift mutations in microsatellite deficient colorectal cancer. PLoS One. 2011; 6(8):e23320.
    View in: PubMed
    Score: 0.002
  30. Season of conception in rural gambia affects DNA methylation at putative human metastable epialleles. PLoS Genet. 2010 Dec 23; 6(12):e1001252.
    View in: PubMed
    Score: 0.002
  31. Association between folate levels and CpG Island hypermethylation in normal colorectal mucosa. Cancer Prev Res (Phila). 2010 Dec; 3(12):1552-64.
    View in: PubMed
    Score: 0.002
  32. Characteristic methylation profile in CpG island methylator phenotype-negative distal colorectal cancers. Int J Cancer. 2010 Nov 01; 127(9):2095-105.
    View in: PubMed
    Score: 0.002
  33. Genome architecture marked by retrotransposons modulates predisposition to DNA methylation in cancer. Genome Res. 2010 Oct; 20(10):1369-82.
    View in: PubMed
    Score: 0.002
  34. Characterization of microRNAs involved in embryonic stem cell states. Stem Cells Dev. 2010 Jul; 19(7):935-50.
    View in: PubMed
    Score: 0.002
  35. Epigenetic profiles distinguish malignant pleural mesothelioma from lung adenocarcinoma. Cancer Res. 2009 Dec 01; 69(23):9073-82.
    View in: PubMed
    Score: 0.002
  36. Concordant DNA methylation in synchronous colorectal carcinomas. Cancer Prev Res (Phila). 2009 Sep; 2(9):814-22.
    View in: PubMed
    Score: 0.002
  37. IGFBP7 is a p53-responsive gene specifically silenced in colorectal cancer with CpG island methylator phenotype. Carcinogenesis. 2010 Mar; 31(3):342-9.
    View in: PubMed
    Score: 0.002
  38. CpG island methylation profiling in human melanoma cell lines. Melanoma Res. 2009 Jun; 19(3):146-55.
    View in: PubMed
    Score: 0.002
  39. Sensitive and specific detection of early gastric cancer with DNA methylation analysis of gastric washes. Gastroenterology. 2009 Jun; 136(7):2149-58.
    View in: PubMed
    Score: 0.002
  40. Histone deacetylase inhibition elicits an evolutionarily conserved self-renewal program in embryonic stem cells. Cell Stem Cell. 2009 Apr 03; 4(4):359-69.
    View in: PubMed
    Score: 0.002
  41. Global DNA hypomethylation (LINE-1) in the normal colon and lifestyle characteristics and dietary and genetic factors. Cancer Epidemiol Biomarkers Prev. 2009 Apr; 18(4):1041-9.
    View in: PubMed
    Score: 0.002
  42. Hypomethylation of long interspersed nuclear element-1 in hepatocellular carcinomas. Mod Pathol. 2009 Mar; 22(3):442-9.
    View in: PubMed
    Score: 0.002
  43. An Sp1/Sp3 binding polymorphism confers methylation protection. PLoS Genet. 2008 Aug 22; 4(8):e1000162.
    View in: PubMed
    Score: 0.002
  44. Variable DNA methylation patterns associated with progression of disease in hepatocellular carcinomas. Carcinogenesis. 2008 Oct; 29(10):1901-10.
    View in: PubMed
    Score: 0.002
  45. Aberrant CpG island methylation in acute myeloid leukemia is accentuated at relapse. Blood. 2008 Aug 15; 112(4):1366-73.
    View in: PubMed
    Score: 0.002
  46. Gene silencing in cancer by histone H3 lysine 27 trimethylation independent of promoter DNA methylation. Nat Genet. 2008 Jun; 40(6):741-50.
    View in: PubMed
    Score: 0.002
  47. Understanding the development of human bladder cancer by using a whole-organ genomic mapping strategy. Lab Invest. 2008 Jul; 88(7):694-721.
    View in: PubMed
    Score: 0.002
  48. Epigenetic-genetic interactions in the APC/WNT, RAS/RAF, and P53 pathways in colorectal carcinoma. Clin Cancer Res. 2008 May 01; 14(9):2560-9.
    View in: PubMed
    Score: 0.002
  49. Downregulation of histone H3 lysine 9 methyltransferase G9a induces centrosome disruption and chromosome instability in cancer cells. PLoS One. 2008 Apr 30; 3(4):e2037.
    View in: PubMed
    Score: 0.002
  50. Identification of novel tumor markers in prostate, colon and breast cancer by unbiased methylation profiling. PLoS One. 2008 Apr 30; 3(4):e2079.
    View in: PubMed
    Score: 0.002
  51. 15-Lipoxygenase-1 transcriptional silencing by DNA methyltransferase-1 independently of DNA methylation. FASEB J. 2008 Jun; 22(6):1981-92.
    View in: PubMed
    Score: 0.002
  52. Induction of hypomethylation and molecular response after decitabine therapy in patients with chronic myelomonocytic leukemia. Blood. 2008 Feb 15; 111(4):2382-4.
    View in: PubMed
    Score: 0.002
  53. Delta DNMT3B variants regulate DNA methylation in a promoter-specific manner. Cancer Res. 2007 Nov 15; 67(22):10647-52.
    View in: PubMed
    Score: 0.002
  54. High-throughput methylation profiling by MCA coupled to CpG island microarray. Genome Res. 2007 Oct; 17(10):1529-36.
    View in: PubMed
    Score: 0.002
  55. Forerunner genes contiguous to RB1 contribute to the development of in situ neoplasia. Proc Natl Acad Sci U S A. 2007 Aug 21; 104(34):13732-7.
    View in: PubMed
    Score: 0.002
  56. Age-related DNA methylation changes in normal human prostate tissues. Clin Cancer Res. 2007 Jul 01; 13(13):3796-802.
    View in: PubMed
    Score: 0.002
  57. LINE-1 hypomethylation in cancer is highly variable and inversely correlated with microsatellite instability. PLoS One. 2007 May 02; 2(5):e399.
    View in: PubMed
    Score: 0.002
  58. RIL, a LIM gene on 5q31, is silenced by methylation in cancer and sensitizes cancer cells to apoptosis. Cancer Res. 2007 Mar 01; 67(5):1997-2005.
    View in: PubMed
    Score: 0.002
  59. Rare CpG island methylator phenotype in ulcerative colitis-associated neoplasias. Gastroenterology. 2007 Apr; 132(4):1254-60.
    View in: PubMed
    Score: 0.002
  60. Correlation between CpG methylation profiles and hormone receptor status in breast cancers. Breast Cancer Res. 2007; 9(4):R57.
    View in: PubMed
    Score: 0.002
  61. Epigenetic inactivation of EGFR by CpG island hypermethylation in cancer. Cancer Biol Ther. 2006 Nov; 5(11):1494-501.
    View in: PubMed
    Score: 0.002
  62. Silencing of bidirectional promoters by DNA methylation in tumorigenesis. Cancer Res. 2006 May 15; 66(10):5077-84.
    View in: PubMed
    Score: 0.002
  63. DNA methylation changes after 5-aza-2'-deoxycytidine therapy in patients with leukemia. Cancer Res. 2006 May 15; 66(10):5495-503.
    View in: PubMed
    Score: 0.002
  64. Decitabine improves patient outcomes in myelodysplastic syndromes: results of a phase III randomized study. Cancer. 2006 Apr 15; 106(8):1794-803.
    View in: PubMed
    Score: 0.002
  65. Vascular endothelial growth factor receptor-1 activation mediates epithelial to mesenchymal transition in human pancreatic carcinoma cells. Cancer Res. 2006 Jan 01; 66(1):46-51.
    View in: PubMed
    Score: 0.002
  66. CIMP, at last. Gastroenterology. 2005 Sep; 129(3):1121-4.
    View in: PubMed
    Score: 0.002
  67. Phenotype of microsatellite-stable colorectal carcinomas with CpG island methylation. Am J Surg Pathol. 2005 Apr; 29(4):429-36.
    View in: PubMed
    Score: 0.002
  68. Chromatin immunoprecipitation microarrays for identification of genes silenced by histone H3 lysine 9 methylation. Proc Natl Acad Sci U S A. 2004 May 11; 101(19):7398-403.
    View in: PubMed
    Score: 0.001
  69. Critical role of histone methylation in tumor suppressor gene silencing in colorectal cancer. Mol Cell Biol. 2003 Jan; 23(1):206-15.
    View in: PubMed
    Score: 0.001
  70. HLTF gene silencing in human colon cancer. Proc Natl Acad Sci U S A. 2002 Apr 02; 99(7):4562-7.
    View in: PubMed
    Score: 0.001
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.