DONALDPARSONSDONALD PARSONS0.000000000000000.000000000000001458PARSONS, DONALD0000-0002-8775-3501Professorplugins:TwitterTwitterprns:coAuthorOfcoauthor ofprns:endDateend dateFaculty Rankprns:fullNamefull nameprns:grantAwardedBygrant awarded byprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:physicalNeighborOfphysical neighborprns:pluginSearchableDataProfilesRNS Plugin Searchable Dataprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:principalInvestigatorNameprincipal investigator nameprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:startDatestart dateprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressvivo:address1address line 1vivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provinceAgreementvivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentDivisionGrantvivo:hasMemberRolemember ofvivo:hasResearchArearesearch areasvivo:hasResearcherRoleresearch activitiesvivo:hrJobTitleHR job titleInformation Resourcevivo:linkAnchorTextlink anchor textvivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressMember Rolevivo:memberRoleOfmember role ofvivo:orcidIdORCID idvivo:personInPositionpositionsPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titleResearcher Rolevivo:researcherRoleOfresearcher role ofRolevivo:roleContributesTocontributes tovivo:sponsorAwardIdsponsor award idURLLinkvivo:webpagewebpagerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst nameGroupfoaf:lastNamelast nameOrganizationPerson25482530Bainbridge MN, Armstrong GN, Gramatges MM, Bertuch AA, Jhangiani SN, Doddapaneni H, Lewis L, Tombrello J, Tsavachidis S, Liu Y, Jalali A, Plon SE, Lau CC, Parsons DW, Claus EB, Barnholtz-Sloan J, Il'yasova D, Schildkraut J, Ali-Osman F, Sadetzki S, Johansen C, Houlston RS, Jenkins RB, Lachance D, Olson SH, Bernstein JL, Merrell RT, Wrensch MR, Walsh KM, Davis FG, Lai R, Shete S, Aldape K, Amos CI, Thompson PA, Muzny DM, Gibbs RA, Melin BS, Bondy ML, Gliogene ConsortiumJournal of the National Cancer InstituteGermline mutations in shelterin complex genes are associated with familial glioma. J Natl Cancer Inst. 2015 Jan; 107(1):384.J Natl Cancer Inst2014-12-07T00:00:002014Germline mutations in shelterin complex genes are associated with familial glioma.Authorship 15669516Authorship 1566962Authorship 1566971Authorship 156698125360585Peters TL, Kumar V, Polikepahad S, Lin FY, Sarabia SF, Liang Y, Wang WL, Lazar AJ, Doddapaneni H, Chao H, Muzny DM, Wheeler DA, Okcu MF, Plon SE, Hicks MJ, L?pez-Terrada D, Parsons DW, Roy AModern pathology : an official journal of the United States and Canadian Academy of Pathology, IncBCOR-CCNB3 fusions are frequent in undifferentiated sarcomas of male children. Mod Pathol. 2015 Apr; 28(4):575-86.Mod Pathol2014-10-31T00:00:002014BCOR-CCNB3 fusions are frequent in undifferentiated sarcomas of male children.19350208Holdhoff M, Parsons DW, Diaz LAJournal of neuro-oncologyMutations of IDH1 and IDH2 are not detected in brain metastases of colorectal cancer. J Neurooncol. 2009 Sep; 94(2):297.J Neurooncol2009-04-07T00:00:002009Mutations of IDH1 and IDH2 are not detected in brain metastases of colorectal cancer.18772396Parsons DW, Jones S, Zhang X, Lin JC, Leary RJ, Angenendt P, Mankoo P, Carter H, Siu IM, Gallia GL, Olivi A, McLendon R, Rasheed BA, Keir S, Nikolskaya T, Nikolsky Y, Busam DA, Tekleab H, Diaz LA, Hartigan J, Smith DR, Strausberg RL, Marie SK, Shinjo SM, Yan H, Riggins GJ, Bigner DD, Karchin R, Papadopoulos N, Parmigiani G, Vogelstein B, Velculescu VE, Kinzler KWScience (New York, N.Y.)An integrated genomic analysis of human glioblastoma multiforme. Science. 2008 Sep 26; 321(5897):1807-12.Science2008-09-04T00:00:002008An integrated genomic analysis of human glioblastoma multiforme.16094359Parsons DW, Wang TL, Samuels Y, Bardelli A, Cummins JM, DeLong L, Silliman N, Ptak J, Szabo S, Willson JK, Markowitz S, Kinzler KW, Vogelstein B, Lengauer C, Velculescu VENatureColorectal cancer: mutations in a signalling pathway. Nature. 2005 Aug 11; 436(7052):792.Nature2005-08-11T00:00:002005Colorectal cancer: mutations in a signalling pathway.Authorship 826282SARAHSCOLLONSARAH SCOLLON8216SCOLLON, SARAHAssistant ProfessorAuthorship 951034Authorship 971645Authorship 993926Authorship 310042Authorship 335111Investigational Cancer TherapeuticsLeukemiaPalliative Care & Rehabilitation MedicineSystems BiologyMD AndersonHAGOP MKANTARJIANHAGOP M KANTARJIAN8501KANTARJIAN, HAGOP MProfessorGORDON BMILLSGORDON B MILLS8620MILLS, GORDON BProfessorEDUARDOBRUERAEDUARDO BRUERA8804BRUERA, EDUARDOProfessorFUNDAMERIC-BERNSTAMFUNDA MERIC-BERNSTAM8778MERIC-BERNSTAM, FUNDAProfessorAuthorship 424652Authorship 448985Authorship 64612Authorship 677334Authorship 844497Authorship 8841Authorship 966112Authorship 2801372Authorship 2801383726181361Berg SL, Parsons DWJAMA oncologyThe Pharmacogenomics of Vincristine-Induced Neuropathy: On Pins and Needles. JAMA Oncol. 2015 Oct; 1(7):975-6.JAMA Oncol2015-10-01T00:00:002015The Pharmacogenomics of Vincristine-Induced Neuropathy: On Pins and Needles.26061751Cancer Genome Atlas Research Network, Brat DJ, Verhaak RG, Aldape KD, Yung WK, Salama SR, Cooper LA, Rheinbay E, Miller CR, Vitucci M, Morozova O, Robertson AG, Noushmehr H, Laird PW, Cherniack AD, Akbani R, Huse JT, Ciriello G, Poisson LM, Barnholtz-Sloan JS, Berger MS, Brennan C, Colen RR, Colman H, Flanders AE, Giannini C, Grifford M, Iavarone A, Jain R, Joseph I, Kim J, Kasaian K, Mikkelsen T, Murray BA, O'Neill BP, Pachter L, Parsons DW, Sougnez C, Sulman EP, Vandenberg SR, Van Meir EG, von Deimling A, Zhang H, Crain D, Lau K, Mallery D, Morris S, Paulauskis J, Penny R, Shelton T, Sherman M, Yena P, Black A, Bowen J, Dicostanzo K, Gastier-Foster J, Leraas KM, Lichtenberg TM, Pierson CR, Ramirez NC, Taylor C, Weaver S, Wise L, Zmuda E, Davidsen T, Demchok JA, Eley G, Ferguson ML, Hutter CM, Mills Shaw KR, Ozenberger BA, Sheth M, Sofia HJ, Tarnuzzer R, Wang Z, Yang L, Zenklusen JC, Ayala B, Baboud J, Chudamani S, Jensen MA, Liu J, Pihl T, Raman R, Wan Y, Wu Y, Ally A, Auman JT, Balasundaram M, Balu S, Baylin SB, Beroukhim R, Bootwalla MS, Bowlby R, Bristow CA, Brooks D, Butterfield Y, Carlsen R, Carter S, Chin L, Chu A, Chuah E, Cibulskis K, Clarke A, Coetzee SG, Dhalla N, Fennell T, Fisher S, Gabriel S, Getz G, Gibbs R, Guin R, Hadjipanayis A, Hayes DN, Hinoue T, Hoadley K, Holt RA, Hoyle AP, Jefferys SR, Jones S, Jones CD, Kucherlapati R, Lai PH, Lander E, Lee S, Lichtenstein L, Ma Y, Maglinte DT, Mahadeshwar HS, Marra MA, Mayo M, Meng S, Meyerson ML, Mieczkowski PA, Moore RA, Mose LE, Mungall AJ, Pantazi A, Parfenov M, Park PJ, Parker JS, Perou CM, Protopopov A, Ren X, Roach J, Sabedot TS, Schein J, Schumacher SE, Seidman JG, Seth S, Shen H, Simons JV, Sipahimalani P, Soloway MG, Song X, Sun H, Tabak B, Tam A, Tan D, Tang J, Thiessen N, Triche T, Van Den Berg DJ, Veluvolu U, Waring S, Weisenberger DJ, Wilkerson MD, Wong T, Wu J, Xi L, Xu AW, Yang L, Zack TI, Zhang J, Aksoy BA, Arachchi H, Benz C, Bernard B, Carlin D, Cho J, DiCara D, Frazer S, Fuller GN, Gao J, Gehlenborg N, Haussler D, Heiman DI, Iype L, Jacobsen A, Ju Z, Katzman S, Kim H, Knijnenburg T, Kreisberg RB, Lawrence MS, Lee W, Leinonen K, Lin P, Ling S, Liu W, Liu Y, Liu Y, Lu Y, Mills G, Ng S, Noble MS, Paull E, Rao A, Reynolds S, Saksena G, Sanborn Z, Sander C, Schultz N, Senbabaoglu Y, Shen R, Shmulevich I, Sinha R, Stuart J, Sumer SO, Sun Y, Tasman N, Taylor BS, Voet D, Weinhold N, Weinstein JN, Yang D, Yoshihara K, Zheng S, Zhang W, Zou L, Abel T, Sadeghi S, Cohen ML, Eschbacher J, Hattab EM, Raghunathan A, Schniederjan MJ, Aziz D, Barnett G, Barrett W, Bigner DD, Boice L, Brewer C, Calatozzolo C, Campos B, Carlotti CG, Chan TA, Cuppini L, Curley E, Cuzzubbo S, Devine K, DiMeco F, Duell R, Elder JB, Fehrenbach A, Finocchiaro G, Friedman W, Fulop J, Gardner J, Hermes B, Herold-Mende C, Jungk C, Kendler A, Lehman NL, Lipp E, Liu O, Mandt R, McGraw M, Mclendon R, McPherson C, Neder L, Nguyen P, Noss A, Nunziata R, Ostrom QT, Palmer C, Perin A, Pollo B, Potapov A, Potapova O, Rathmell WK, Rotin D, Scarpace L, Schilero C, Senecal K, Shimmel K, Shurkhay V, Sifri S, Singh R, Sloan AE, Smolenski K, Staugaitis SM, Steele R, Thorne L, Tirapelli DP, Unterberg A, Vallurupalli M, Wang Y, Warnick R, Williams F, Wolinsky Y, Bell S, Rosenberg M, Stewart C, Huang F, Grimsby JL, Radenbaugh AJ, Zhang JThe New England journal of medicineComprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas. N Engl J Med. 2015 Jun 25; 372(26):2481-98.N Engl J Med2015-06-10T00:00:002015Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas.1102 BATESHouston, 77030TX9199562McAndrew PE, Parsons DW, Simard LR, Rochette C, Ray PN, Mendell JR, Prior TW, Burghes AHAmerican journal of human geneticsIdentification of proximal spinal muscular atrophy carriers and patients by analysis of SMNT and SMNC gene copy number. Am J Hum Genet. 1997 Jun; 60(6):1411-22.Am J Hum Genet1997-06-01T00:00:001997Identification of proximal spinal muscular atrophy carriers and patients by analysis of SMNT and SMNC gene copy number.Authorship 28138219837824Parsons DW, McAndrew PE, Iannaccone ST, Mendell JR, Burghes AH, Prior TWAmerican journal of human geneticsIntragenic telSMN mutations: frequency, distribution, evidence of a founder effect, and modification of the spinal muscular atrophy phenotype by cenSMN copy number. Am J Hum Genet. 1998 Dec; 63(6):1712-23.Am J Hum Genet1998-12-01T00:00:001998Intragenic telSMN mutations: frequency, distribution, evidence of a founder effect, and modification of the spinal muscular atrophy phenotype by cenSMN copy number.26822237Parsons DW, Roy A, Yang Y, Wang T, Scollon S, Bergstrom K, Kerstein RA, Gutierrez S, Petersen AK, Bavle A, Lin FY, L?pez-Terrada DH, Monzon FA, Hicks MJ, Eldin KW, Quintanilla NM, Adesina AM, Mohila CA, Whitehead W, Jea A, Vasudevan SA, Nuchtern JG, Ramamurthy U, McGuire AL, Hilsenbeck SG, Reid JG, Muzny DM, Wheeler DA, Berg SL, Chintagumpala MM, Eng CM, Gibbs RA, Plon SEJAMA oncologyDiagnostic Yield of Clinical Tumor and Germline Whole-Exome Sequencing for Children With Solid Tumors. JAMA Oncol. 2016 May 01; 2(5):616-624.JAMA Oncol2016-05-01T00:00:002016Diagnostic Yield of Clinical Tumor and Germline Whole-Exome Sequencing for Children With Solid Tumors.10655541Monani UR, Sendtner M, Coovert DD, Parsons DW, Andreassi C, Le TT, Jablonka S, Schrank B, Rossoll W, Rossol W, Prior TW, Morris GE, Burghes AHHuman molecular geneticsThe human centromeric survival motor neuron gene (SMN2) rescues embryonic lethality in Smn(-/-) mice and results in a mouse with spinal muscular atrophy. Hum Mol Genet. 2000 Feb 12; 9(3):333-9.Hum Mol Genet2000-02-12T00:00:002000The human centromeric survival motor neuron gene (SMN2) rescues embryonic lethality in Smn(-/-) mice and results in a mouse with spinal muscular atrophy.Authorship 2994497Authorship 30063422Authorship 3021526Authorship 302326226477867Brothers KB, Holm IA, Childerhose JE, Antommaria AHM, Bernhardt BA, Clayton EW, Gelb BD, Joffe S, Lynch JA, McCormick JB, McCullough LB, Parsons DW, Sundaresan AS, Wolf WA, Yu JH, Wilfond BS, Pediatrics Workgroup of the Clinical Sequencing Exploratory Research (CSER) ConsortiumThe Journal of pediatricsWhen Participants in Genomic Research Grow Up: Contact and Consent at the Age of Majority. J Pediatr. 2016 Jan; 168:226-231.e1.J Pediatr2015-10-23T00:00:002015When Participants in Genomic Research Grow Up: Contact and Consent at the Age of Majority.26479562Scollon S, Bergstrom K, McCullough LB, McGuire AL, Gutierrez S, Kerstein R, Parsons DW, Plon SEThe Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & EthicsPediatric Cancer Genetics Research and an Evolving Preventive Ethics Approach for Return of Results after Death of the Subject. J Law Med Ethics. 2015; 43(3):529-37.J Law Med Ethics2015-01-01T00:00:002015Pediatric Cancer Genetics Research and an Evolving Preventive Ethics Approach for Return of Results after Death of the Subject.26505993McCullough LB, Slashinski MJ, McGuire AL, Street RL, Eng CM, Gibbs RA, Parsons DW, Plon SEPediatric blood & cancerIs Whole-Exome Sequencing an Ethically Disruptive Technology? Perspectives of Pediatric Oncologists and Parents of Pediatric Patients With Solid Tumors. Pediatr Blood Cancer. 2016 Mar; 63(3):511-5.Pediatr Blood Cancer2015-10-27T00:00:002015Is Whole-Exome Sequencing an Ethically Disruptive Technology? Perspectives of Pediatric Oncologists and Parents of Pediatric Patients With Solid Tumors.26573325Roy A, Kumar V, Zorman B, Fang E, Haines KM, Doddapaneni H, Hampton OA, White S, Bavle AA, Patel NR, Eldin KW, John Hicks M, Rakheja D, Leavey PJ, Skapek SX, Amatruda JF, Nuchtern JG, Chintagumpala MM, Wheeler DA, Plon SE, Sumazin P, Parsons DWNature communicationsRecurrent internal tandem duplications of BCOR in clear cell sarcoma of the kidney. Nat Commun. 2015 Nov 17; 6:8891.Nat Commun2015-11-17T00:00:002015Recurrent internal tandem duplications of BCOR in clear cell sarcoma of the kidney.26590952Raymond VM, Gray SW, Roychowdhury S, Joffe S, Chinnaiyan AM, Parsons DW, Plon SE, Clinical Sequencing Exploratory Research Consortium Tumor Working GroupJournal of the National Cancer InstituteGermline Findings in Tumor-Only Sequencing: Points to Consider for Clinicians and Laboratories. J Natl Cancer Inst. 2016 Apr; 108(4).J Natl Cancer Inst2015-11-20T00:00:002015Germline Findings in Tumor-Only Sequencing: Points to Consider for Clinicians and Laboratories.26637772Allen CE, Parsons DWHematology. American Society of Hematology. Education ProgramBiological and clinical significance of somatic mutations in Langerhans cell histiocytosis and related histiocytic neoplastic disorders. Hematology Am Soc Hematol Educ Program. 2015; 2015:559-64.Hematology Am Soc Hematol Educ Program2015-01-01T00:00:002015Biological and clinical significance of somatic mutations in Langerhans cell histiocytosis and related histiocytic neoplastic disorders.8922999Parsons DW, McAndrew PE, Monani UR, Mendell JR, Burghes AH, Prior TWHuman molecular geneticsAn 11 base pair duplication in exon 6 of the SMN gene produces a type I spinal muscular atrophy (SMA) phenotype: further evidence for SMN as the primary SMA-determining gene. Hum Mol Genet. 1996 Nov; 5(11):1727-32.Hum Mol Genet1996-11-01T00:00:001996An 11 base pair duplication in exon 6 of the SMN gene produces a type I spinal muscular atrophy (SMA) phenotype: further evidence for SMN as the primary SMA-determining gene.12738854Bardelli A, Parsons DW, Silliman N, Ptak J, Szabo S, Saha S, Markowitz S, Willson JK, Parmigiani G, Kinzler KW, Vogelstein B, Velculescu VEScience (New York, N.Y.)Mutational analysis of the tyrosine kinome in colorectal cancers. Science. 2003 May 09; 300(5621):949.Science2003-05-09T00:00:002003Mutational analysis of the tyrosine kinome in colorectal cancers.10369862Monani UR, Lorson CL, Parsons DW, Prior TW, Androphy EJ, Burghes AH, McPherson JDHuman molecular geneticsA single nucleotide difference that alters splicing patterns distinguishes the SMA gene SMN1 from the copy gene SMN2. Hum Mol Genet. 1999 Jul; 8(7):1177-83.Hum Mol Genet1999-07-01T00:00:001999A single nucleotide difference that alters splicing patterns distinguishes the SMA gene SMN1 from the copy gene SMN2.27117591Bissig-Choisat B, Kettlun-Leyton C, Legras XD, Zorman B, Barzi M, Chen LL, Amin MD, Huang YH, Pautler RG, Hampton OA, Prakash MM, Yang D, Borowiak M, Muzny D, Doddapaneni HV, Hu J, Shi Y, Gaber MW, Hicks MJ, Thompson PA, Lu Y, Mills GB, Finegold M, Goss JA, Parsons DW, Vasudevan SA, Sumazin P, L?pez-Terrada D, Bissig KDJournal of hepatologyNovel patient-derived xenograft and cell line models for therapeutic testing of pediatric liver cancer. J Hepatol. 2016 08; 65(2):325-33.J Hepatol2016-04-23T00:00:002016Novel patient-derived xenograft and cell line models for therapeutic testing of pediatric liver cancer.Authorship 31563744Authorship 31563818Authorship 3156391227181682Green RC, Goddard KAB, Jarvik GP, Amendola LM, Appelbaum PS, Berg JS, Bernhardt BA, Biesecker LG, Biswas S, Blout CL, Bowling KM, Brothers KB, Burke W, Caga-Anan CF, Chinnaiyan AM, Chung WK, Clayton EW, Cooper GM, East K, Evans JP, Fullerton SM, Garraway LA, Garrett JR, Gray SW, Henderson GE, Hindorff LA, Holm IA, Lewis MH, Hutter CM, Janne PA, Joffe S, Kaufman D, Knoppers BM, Koenig BA, Krantz ID, Manolio TA, McCullough L, McEwen J, McGuire A, Muzny D, Myers RM, Nickerson DA, Ou J, Parsons DW, Petersen GM, Plon SE, Rehm HL, Roberts JS, Robinson D, Salama JS, Scollon S, Sharp RR, Shirts B, Spinner NB, Tabor HK, Tarczy-Hornoch P, Veenstra DL, Wagle N, Weck K, Wilfond BS, Wilhelmsen K, Wolf SM, Wynn J, Yu JH, CSER ConsortiumAmerican journal of human geneticsClinical Sequencing Exploratory Research Consortium: Accelerating Evidence-Based Practice of Genomic Medicine. Am J Hum Genet. 2016 06 02; 98(6):1051-1066.Am J Hum Genet2016-05-12T00:00:002016Clinical Sequencing Exploratory Research Consortium: Accelerating Evidence-Based Practice of Genomic Medicine.27132463Hingorani P, Janeway K, Crompton BD, Kadoch C, Mackall CL, Khan J, Shern JF, Schiffman J, Mirabello L, Savage SA, Ladanyi M, Meltzer P, Bult CJ, Adamson PC, Lupo PJ, Mody R, DuBois SG, Parsons DW, Khanna C, Lau C, Hawkins DS, Randall RL, Smith M, Sorensen PH, Plon SE, Skapek SX, Lessnick S, Gorlick R, Reed DRCancer geneticsCurrent state of pediatric sarcoma biology and opportunities for future discovery: A report from the sarcoma translational research workshop. Cancer Genet. 2016 05; 209(5):182-94.Cancer Genet2016-04-05T00:00:002016Current state of pediatric sarcoma biology and opportunities for future discovery: A report from the sarcoma translational research workshop.Authorship 3163432574Professor10Assistant Professor54Instructor14Associate Professor3Adjunct Associate Professor27188671Bavle AA, Lin FY, Parsons DWOncology (Williston Park, N.Y.)Applications of Genomic Sequencing in Pediatric CNS Tumors. Oncology (Williston Park). 2016 May; 30(5):411-23.Oncology (Williston Park)2016-05-01T00:00:002016Applications of Genomic Sequencing in Pediatric CNS Tumors.27626068Lin FY, Bergstrom K, Person R, Bavle A, Ballester LY, Scollon S, Raesz-Martinez R, Jea A, Birchansky S, Wheeler DA, Berg SL, Chintagumpala MM, Adesina AM, Eng C, Roy A, Plon SE, Parsons DWCold Spring Harbor molecular case studiesIntegrated tumor and germline whole-exome sequencing identifies mutations in MAPK and PI3K pathway genes in an adolescent with rosette-forming glioneuronal tumor of the fourth ventricle. Cold Spring Harb Mol Case Stud. 2016 Sep; 2(5):a001057.Cold Spring Harb Mol Case Stud2016-09-01T00:00:002016Integrated tumor and germline whole-exome sequencing identifies mutations in MAPK and PI3K pathway genes in an adolescent with rosette-forming glioneuronal tumor of the fourth ventricle.17693572Lin J, Gan CM, Zhang X, Jones S, Sj?blom T, Wood LD, Parsons DW, Papadopoulos N, Kinzler KW, Vogelstein B, Parmigiani G, Velculescu VEGenome researchA multidimensional analysis of genes mutated in breast and colorectal cancers. Genome Res. 2007 Sep; 17(9):1304-18.Genome Res2007-08-10T00:00:002007A multidimensional analysis of genes mutated in breast and colorectal cancers.15155950Wang Z, Shen D, Parsons DW, Bardelli A, Sager J, Szabo S, Ptak J, Silliman N, Peters BA, van der Heijden MS, Parmigiani G, Yan H, Wang TL, Riggins G, Powell SM, Willson JK, Markowitz S, Kinzler KW, Vogelstein B, Velculescu VEScience (New York, N.Y.)Mutational analysis of the tyrosine phosphatome in colorectal cancers. Science. 2004 May 21; 304(5674):1164-6.Science2004-05-21T00:00:002004Mutational analysis of the tyrosine phosphatome in colorectal cancers.19351817Blackford A, Parmigiani G, Kensler TW, Wolfgang C, Jones S, Zhang X, Parsons DW, Lin JC, Leary RJ, Eshleman JR, Goggins M, Jaffee EM, Iacobuzio-Donahue CA, Maitra A, Klein A, Cameron JL, Olino K, Schulick R, Winter J, Vogelstein B, Velculescu VE, Kinzler KW, Hruban RHCancer researchGenetic mutations associated with cigarette smoking in pancreatic cancer. Cancer Res. 2009 Apr 15; 69(8):3681-8.Cancer Res2009-04-07T00:00:002009Genetic mutations associated with cigarette smoking in pancreatic cancer.21314958Joshi AD, Parsons DW, Velculescu VE, Riggins GJMolecular cancerSodium ion channel mutations in glioblastoma patients correlate with shorter survival. Mol Cancer. 2011 Feb 11; 10:17.Mol Cancer2011-02-11T00:00:002011Sodium ion channel mutations in glioblastoma patients correlate with shorter survival.Authorship 32783715Authorship 32783817Authorship 32783944Authorship 3278403Authorship 327841727729324Chakraborty R, Burke TM, Hampton OA, Zinn DJ, Lim KP, Abhyankar H, Scull B, Kumar V, Kakkar N, Wheeler DA, Roy A, Poulikakos PI, Merad M, McClain KL, Parsons DW, Allen CEBloodAlternative genetic mechanisms of BRAF activation in Langerhans cell histiocytosis. Blood. 2016 11 24; 128(21):2533-2537.Blood2016-10-11T00:00:002016Alternative genetic mechanisms of BRAF activation in Langerhans cell histiocytosis.27748010Potter SL, Venkatramani R, Wenderfer S, Graham BH, Vasudevan SA, Sher A, Wu H, Wheeler DA, Yang Y, Eng CM, Gibbs RA, Roy A, Plon SE, Parsons DWPediatric blood & cancerRenal cell carcinoma harboring somatic TSC2 mutations in a child with methylmalonic acidemia. Pediatr Blood Cancer. 2017 05; 64(5).Pediatr Blood Cancer2016-10-17T00:00:002016Renal cell carcinoma harboring somatic TSC2 mutations in a child with methylmalonic acidemia.Authorship 37490617Authorship 3749121427775819Sumazin P, Chen Y, Trevi?o LR, Sarabia SF, Hampton OA, Patel K, Mistretta TA, Zorman B, Thompson P, Heczey A, Comerford S, Wheeler DA, Chintagumpala M, Meyers R, Rakheja D, Finegold MJ, Tomlinson G, Parsons DW, L?pez-Terrada DHepatology (Baltimore, Md.)Genomic analysis of hepatoblastoma identifies distinct molecular and prognostic subgroups. Hepatology. 2017 01; 65(1):104-121.Hepatology2016-11-29T00:00:002016Genomic analysis of hepatoblastoma identifies distinct molecular and prognostic subgroups.27814769Ritter DI, Roychowdhury S, Roy A, Rao S, Landrum MJ, Sonkin D, Shekar M, Davis CF, Hart RK, Micheel C, Weaver M, Van Allen EM, Parsons DW, McLeod HL, Watson MS, Plon SE, Kulkarni S, Madhavan S, ClinGen Somatic Cancer Working GroupGenome medicineSomatic cancer variant curation and harmonization through consensus minimum variant level data. Genome Med. 2016 11 04; 8(1):117.Genome Med2016-11-04T00:00:002016Somatic cancer variant curation and harmonization through consensus minimum variant level data.18245491Segal NH, Parsons DW, Peggs KS, Velculescu V, Kinzler KW, Vogelstein B, Allison JPCancer researchEpitope landscape in breast and colorectal cancer. Cancer Res. 2008 Feb 01; 68(3):889-92.Cancer Res2008-02-01T00:00:002008Epitope landscape in breast and colorectal cancer.17932254Wood LD, Parsons DW, Jones S, Lin J, Sj?blom T, Leary RJ, Shen D, Boca SM, Barber T, Ptak J, Silliman N, Szabo S, Dezso Z, Ustyanksky V, Nikolskaya T, Nikolsky Y, Karchin R, Wilson PA, Kaminker JS, Zhang Z, Croshaw R, Willis J, Dawson D, Shipitsin M, Willson JK, Sukumar S, Polyak K, Park BH, Pethiyagoda CL, Pant PV, Ballinger DG, Sparks AB, Hartigan J, Smith DR, Suh E, Papadopoulos N, Buckhaults P, Markowitz SD, Parmigiani G, Kinzler KW, Velculescu VE, Vogelstein BScience (New York, N.Y.)The genomic landscapes of human breast and colorectal cancers. Science. 2007 Nov 16; 318(5853):1108-13.Science2007-10-11T00:00:002007The genomic landscapes of human breast and colorectal cancers.18772397Jones S, Zhang X, Parsons DW, Lin JC, Leary RJ, Angenendt P, Mankoo P, Carter H, Kamiyama H, Jimeno A, Hong SM, Fu B, Lin MT, Calhoun ES, Kamiyama M, Walter K, Nikolskaya T, Nikolsky Y, Hartigan J, Smith DR, Hidalgo M, Leach SD, Klein AP, Jaffee EM, Goggins M, Maitra A, Iacobuzio-Donahue C, Eshleman JR, Kern SE, Hruban RH, Karchin R, Papadopoulos N, Parmigiani G, Vogelstein B, Velculescu VE, Kinzler KWScience (New York, N.Y.)Core signaling pathways in human pancreatic cancers revealed by global genomic analyses. Science. 2008 Sep 26; 321(5897):1801-6.Science2008-09-04T00:00:002008Core signaling pathways in human pancreatic cancers revealed by global genomic analyses.18852474Leary RJ, Lin JC, Cummins J, Boca S, Wood LD, Parsons DW, Jones S, Sj?blom T, Park BH, Parsons R, Willis J, Dawson D, Willson JK, Nikolskaya T, Nikolsky Y, Kopelovich L, Papadopoulos N, Pennacchio LA, Wang TL, Markowitz SD, Parmigiani G, Kinzler KW, Vogelstein B, Velculescu VEProceedings of the National Academy of Sciences of the United States of AmericaIntegrated analysis of homozygous deletions, focal amplifications, and sequence alterations in breast and colorectal cancers. Proc Natl Acad Sci U S A. 2008 Oct 21; 105(42):16224-9.Proc Natl Acad Sci U S A2008-10-13T00:00:002008Integrated analysis of homozygous deletions, focal amplifications, and sequence alterations in breast and colorectal cancers.19584151Blackford A, Serrano OK, Wolfgang CL, Parmigiani G, Jones S, Zhang X, Parsons DW, Lin JC, Leary RJ, Eshleman JR, Goggins M, Jaffee EM, Iacobuzio-Donahue CA, Maitra A, Cameron JL, Olino K, Schulick R, Winter J, Herman JM, Laheru D, Klein AP, Vogelstein B, Kinzler KW, Velculescu VE, Hruban RHClinical cancer research : an official journal of the American Association for Cancer ResearchSMAD4 gene mutations are associated with poor prognosis in pancreatic cancer. Clin Cancer Res. 2009 Jul 15; 15(14):4674-9.Clin Cancer Res2009-07-07T00:00:002009SMAD4 gene mutations are associated with poor prognosis in pancreatic cancer.Authorship 653416228010789Heikamp EB, Parsons DW, Plon SEThe Journal of pediatrics50 Years Ago in The Journal of Pediatrics: Adrenocortical Neoplasms with Hemihypertrophy, Brain Tumors, and Other Disorders. J Pediatr. 2017 01; 180:115.J Pediatr2017-01-01T00:00:00201750 Years Ago in The Journal of Pediatrics: Adrenocortical Neoplasms with Hemihypertrophy, Brain Tumors, and Other Disorders.19996293Yan H, Bigner DD, Velculescu V, Parsons DWCancer researchMutant metabolic enzymes are at the origin of gliomas. Cancer Res. 2009 Dec 15; 69(24):9157-9.Cancer Res2009-12-15T00:00:002009Mutant metabolic enzymes are at the origin of gliomas.21304175Parsons DWOncotargetThe evolving picture of the glioblastoma genome. Oncotarget. 2010 Aug; 1(4):237-8.Oncotarget2010-08-01T00:00:002010The evolving picture of the glioblastoma genome.22009941Jones S, Li M, Parsons DW, Zhang X, Wesseling J, Kristel P, Schmidt MK, Markowitz S, Yan H, Bigner D, Hruban RH, Eshleman JR, Iacobuzio-Donahue CA, Goggins M, Maitra A, Malek SN, Powell S, Vogelstein B, Kinzler KW, Velculescu VE, Papadopoulos NHuman mutationSomatic mutations in the chromatin remodeling gene ARID1A occur in several tumor types. Hum Mutat. 2012 Jan; 33(1):100-3.Hum Mutat2011-11-23T00:00:002011Somatic mutations in the chromatin remodeling gene ARID1A occur in several tumor types.Authorship 7851004Authorship 7854191327392080Green RC, Goddard KA, Jarvik GP, Amendola LM, Appelbaum PS, Berg JS, Bernhardt BA, Biesecker LG, Biswas S, Blout CL, Bowling KM, Brothers KB, Burke W, Caga-Anan CF, Chinnaiyan AM, Chung WK, Clayton EW, Cooper GM, East K, Evans JP, Fullerton SM, Garraway LA, Garrett JR, Gray SW, Henderson GE, Hindorff LA, Holm IA, Lewis MH, Hutter CM, Janne PA, Joffe S, Kaufman D, Knoppers BM, Koenig BA, Krantz ID, Manolio TA, McCullough L, McEwen J, McGuire A, Muzny D, Myers RM, Nickerson DA, Ou J, Parsons DW, Petersen GM, Plon SE, Rehm HL, Roberts JS, Robinson D, Salama JS, Scollon S, Sharp RR, Shirts B, Spinner NB, Tabor HK, Tarczy-Hornoch P, Veenstra DL, Wagle N, Weck K, Wilfond BS, Wilhelmsen K, Wolf SM, Wynn J, Yu JH, CSER ConsortiumAmerican journal of human geneticsClinical Sequencing Exploratory Research Consortium: Accelerating Evidence-Based Practice of Genomic Medicine. Am J Hum Genet. 2016 07 07; 99(1):246.Am J Hum Genet2016-07-07T00:00:002016Clinical Sequencing Exploratory Research Consortium: Accelerating Evidence-Based Practice of Genomic Medicine.27748023Mody RJ, Prensner JR, Everett J, Parsons DW, Chinnaiyan AMPediatric blood & cancerPrecision medicine in pediatric oncology: Lessons learned and next steps. Pediatr Blood Cancer. 2017 03; 64(3).Pediatr Blood Cancer2016-10-17T00:00:002016Precision medicine in pediatric oncology: Lessons learned and next steps.Authorship 8686521128343740Seibel NL, Janeway K, Allen CE, Chi SN, Cho YJ, Glade Bender JL, Kim A, Laetsch TW, Irwin MS, Takebe N, Tricoli JV, Parsons DWCurrent problems in cancerPediatric oncology enters an era of precision medicine. Curr Probl Cancer. 2017 May - Jun; 41(3):194-200.Curr Probl Cancer2017-02-01T00:00:002017Pediatric oncology enters an era of precision medicine.Authorship 868896828376230Allen CE, Laetsch TW, Mody R, Irwin MS, Lim MS, Adamson PC, Seibel NL, Parsons DW, Cho YJ, Janeway K, Pediatric MATCH Target and Agent Prioritization CommitteeJournal of the National Cancer InstituteTarget and Agent Prioritization for the Children's Oncology Group-National Cancer Institute Pediatric MATCH Trial. J Natl Cancer Inst. 2017 05 01; 109(5).J Natl Cancer Inst2017-05-01T00:00:002017Target and Agent Prioritization for the Children's Oncology Group-National Cancer Institute Pediatric MATCH Trial.Authorship 8698541928512266Chakraborty R, Hampton OA, Abhyankar H, Zinn DJ, Grimes A, Skull B, Eckstein O, Mahmood N, Wheeler DA, Lopez-Terrada D, Peters TL, Hicks JM, Elghetany T, Krance R, Poulikakos PI, Merad M, McClain KL, Allen CE, Parsons DWOncotargetActivating MAPK1 (ERK2) mutation in an aggressive case of disseminated juvenile xanthogranuloma. Oncotarget. 2017 Jul 11; 8(28):46065-46070.Oncotarget2017-07-11T00:00:002017Activating MAPK1 (ERK2) mutation in an aggressive case of disseminated juvenile xanthogranuloma.9719377Parsons DW, McAndrew PE, Allinson PS, Parker WD, Burghes AH, Prior TWJournal of medical geneticsDiagnosis of spinal muscular atrophy in an SMN non-deletion patient using a quantitative PCR screen and mutation analysis. J Med Genet. 1998 Aug; 35(8):674-6.J Med Genet1998-08-01T00:00:001998Diagnosis of spinal muscular atrophy in an SMN non-deletion patient using a quantitative PCR screen and mutation analysis.Authorship 872761228609651Bavle A, Parsons DWCancer cellFrom One to Many: Further Refinement of Medulloblastoma Subtypes Offers Promise for Personalized Therapy. Cancer Cell. 2017 06 12; 31(6):727-729.Cancer Cell2017-06-12T00:00:002017From One to Many: Further Refinement of Medulloblastoma Subtypes Offers Promise for Personalized Therapy.15126332Wang Z, Cummins JM, Shen D, Cahill DP, Jallepalli PV, Wang TL, Parsons DW, Traverso G, Awad M, Silliman N, Ptak J, Szabo S, Willson JK, Markowitz SD, Goldberg ML, Karess R, Kinzler KW, Vogelstein B, Velculescu VE, Lengauer CCancer researchThree classes of genes mutated in colorectal cancers with chromosomal instability. Cancer Res. 2004 May 01; 64(9):2998-3001.Cancer Res2004-05-01T00:00:002004Three classes of genes mutated in colorectal cancers with chromosomal instability.16959974Sj?blom T, Jones S, Wood LD, Parsons DW, Lin J, Barber TD, Mandelker D, Leary RJ, Ptak J, Silliman N, Szabo S, Buckhaults P, Farrell C, Meeh P, Markowitz SD, Willis J, Dawson D, Willson JK, Gazdar AF, Hartigan J, Wu L, Liu C, Parmigiani G, Park BH, Bachman KE, Papadopoulos N, Vogelstein B, Kinzler KW, Velculescu VEScience (New York, N.Y.)The consensus coding sequences of human breast and colorectal cancers. Science. 2006 Oct 13; 314(5797):268-74.Science2006-09-07T00:00:002006The consensus coding sequences of human breast and colorectal cancers.19228619Yan H, Parsons DW, Jin G, McLendon R, Rasheed BA, Yuan W, Kos I, Batinic-Haberle I, Jones S, Riggins GJ, Friedman H, Friedman A, Reardon D, Herndon J, Kinzler KW, Velculescu VE, Vogelstein B, Bigner DDThe New England journal of medicineIDH1 and IDH2 mutations in gliomas. N Engl J Med. 2009 Feb 19; 360(8):765-73.N Engl J Med2009-02-19T00:00:002009IDH1 and IDH2 mutations in gliomas.19264984Jones S, Hruban RH, Kamiyama M, Borges M, Zhang X, Parsons DW, Lin JC, Palmisano E, Brune K, Jaffee EM, Iacobuzio-Donahue CA, Maitra A, Parmigiani G, Kern SE, Velculescu VE, Kinzler KW, Vogelstein B, Eshleman JR, Goggins M, Klein APScience (New York, N.Y.)Exomic sequencing identifies PALB2 as a pancreatic cancer susceptibility gene. Science. 2009 Apr 10; 324(5924):217.Science2009-03-05T00:00:002009Exomic sequencing identifies PALB2 as a pancreatic cancer susceptibility gene.20227034Reitman ZJ, Parsons DW, Yan HCancer cellIDH1 and IDH2: not your typical oncogenes. Cancer Cell. 2010 Mar 16; 17(3):215-6.Cancer Cell2010-03-16T00:00:002010IDH1 and IDH2: not your typical oncogenes.21163964Parsons DW, Li M, Zhang X, Jones S, Leary RJ, Lin JC, Boca SM, Carter H, Samayoa J, Bettegowda C, Gallia GL, Jallo GI, Binder ZA, Nikolsky Y, Hartigan J, Smith DR, Gerhard DS, Fults DW, VandenBerg S, Berger MS, Marie SK, Shinjo SM, Clara C, Phillips PC, Minturn JE, Biegel JA, Judkins AR, Resnick AC, Storm PB, Curran T, He Y, Rasheed BA, Friedman HS, Keir ST, McLendon R, Northcott PA, Taylor MD, Burger PC, Riggins GJ, Karchin R, Parmigiani G, Bigner DD, Yan H, Papadopoulos N, Vogelstein B, Kinzler KW, Velculescu VEScience (New York, N.Y.)The genetic landscape of the childhood cancer medulloblastoma. Science. 2011 Jan 28; 331(6016):435-9.Science2010-12-16T00:00:002010The genetic landscape of the childhood cancer medulloblastoma.22134537Taylor MD, Northcott PA, Korshunov A, Remke M, Cho YJ, Clifford SC, Eberhart CG, Parsons DW, Rutkowski S, Gajjar A, Ellison DW, Lichter P, Gilbertson RJ, Pomeroy SL, Kool M, Pfister SMActa neuropathologicaMolecular subgroups of medulloblastoma: the current consensus. Acta Neuropathol. 2012 Apr; 123(4):465-72.Acta Neuropathol2011-12-02T00:00:002011Molecular subgroups of medulloblastoma: the current consensus.22183980Chavan RS, Patel KU, Roy A, Thompson PA, Chintagumpala M, Goss JA, Nuchtern JG, Finegold MJ, Parsons DW, L?pez-Terrada DHPediatric blood & cancerMutations of PTCH1, MLL2, and MLL3 are not frequent events in hepatoblastoma. Pediatr Blood Cancer. 2012 Jun; 58(6):1006-7.Pediatr Blood Cancer2011-12-19T00:00:002011Mutations of PTCH1, MLL2, and MLL3 are not frequent events in hepatoblastoma.28935696Peckham-Gregory EC, Chakraborty R, Scheurer ME, Belmont JW, Abhyankar H, Sengal AG, Scull BP, Eckstein O, Zinn DJ, Mayer L, Shih A, Merad M, Parsons DW, McClain KL, Lupo PJ, Allen CEBloodA genome-wide association study of LCH identifies a variant in SMAD6 associated with susceptibility. Blood. 2017 11 16; 130(20):2229-2232.Blood2017-09-21T00:00:002017A genome-wide association study of LCH identifies a variant in SMAD6 associated with susceptibility.Authorship 87945213Authorship 88207811Authorship 8832452428942966Stankiewicz P, Khan TN, Szafranski P, Slattery L, Streff H, Vetrini F, Bernstein JA, Brown CW, Rosenfeld JA, Rednam S, Scollon S, Bergstrom KL, Parsons DW, Plon SE, Vieira MW, Quaio CRDC, Baratela WAR, Acosta Guio JC, Armstrong R, Mehta SG, Rump P, Pfundt R, Lewandowski R, Fernandes EM, Shinde DN, Tang S, Hoyer J, Zweier C, Reis A, Bacino CA, Xiao R, Breman AM, Smith JL, Deciphering Developmental Disorders Study, Katsanis N, Bostwick B, Popp B, Davis EE, Yang YAmerican journal of human geneticsHaploinsufficiency of the Chromatin Remodeler BPTF Causes Syndromic Developmental and Speech Delay, Postnatal Microcephaly, and Dysmorphic Features. Am J Hum Genet. 2017 Oct 05; 101(4):503-515.Am J Hum Genet2017-09-21T00:00:002017Haploinsufficiency of the Chromatin Remodeler BPTF Causes Syndromic Developmental and Speech Delay, Postnatal Microcephaly, and Dysmorphic Features.29152094Kogiso M, Qi L, Lindsay H, Huang Y, Zhao X, Liu Z, Braun FK, Du Y, Zhang H, Bae G, Zhao S, Injac SG, Sobieski M, Brunell D, Mehta V, Tran D, Murray J, Baxter PA, Yuan XJ, Su JM, Adesina A, Perlaky L, Chintagumpala M, Parsons DW, Lau CC, Stephan CC, Lu X, Li XNOncotargetXenotransplantation of pediatric low grade gliomas confirms the enrichment of BRAF V600E mutation and preservation of CDKN2A deletion in a novel orthotopic xenograft mouse model of progressive pleomorphic xanthoastrocytoma. Oncotarget. 2017 Oct 20; 8(50):87455-87471.Oncotarget2017-09-08T00:00:002017Xenotransplantation of pediatric low grade gliomas confirms the enrichment of BRAF V600E mutation and preservation of CDKN2A deletion in a novel orthotopic xenograft mouse model of progressive pleomorphic xanthoastrocytoma.29691299Laetsch TW, Roy A, Xu L, Black JO, Coffin CM, Chi YY, Tian J, Spunt SL, Hawkins DS, Bridge JA, Parsons DW, Skapek SXClinical cancer research : an official journal of the American Association for Cancer ResearchUndifferentiated Sarcomas in Children Harbor Clinically Relevant Oncogenic Fusions and Gene Copy-Number Alterations: A Report from the Children's Oncology Group. Clin Cancer Res. 2018 08 15; 24(16):3888-3897.Clin Cancer Res2018-04-24T00:00:002018Undifferentiated Sarcomas in Children Harbor Clinically Relevant Oncogenic Fusions and Gene Copy-Number Alterations: A Report from the Children's Oncology Group.true1ProfessorProfessortrue1ProfessorProfessortrue1Associate ProfessorAssociate Professortrue1InstructorInstructorAuthorship 89000813D009154Physiology2018151490.239339MutationD016543Disorders2295020.685613Central Nervous System Neoplasms29624648McClain KL, Picarsic J, Chakraborty R, Zinn D, Lin H, Abhyankar H, Scull B, Shih A, Lim KPH, Eckstein O, Lubega J, Peters TL, Olea W, Burke T, Ahmed N, Hicks MJ, Tran B, Jones J, Dauser R, Jeng M, Baiocchi R, Schiff D, Goldman S, Heym KM, Wilson H, Carcamo B, Kumar A, Rodriguez-Galindo C, Whipple NS, Campbell P, Murdoch G, Kofler J, Heales S, Malone M, Woltjer R, Quinn JF, Orchard P, Kruer MC, Jaffe R, Manz MG, Lira SA, Parsons DW, Merad M, Man TK, Allen CECancerCNS Langerhans cell histiocytosis: Common hematopoietic origin for LCH-associated neurodegeneration and mass lesions. Cancer. 2018 06 15; 124(12):2607-2620.Cancer2018-04-06T00:00:002018CNS Langerhans cell histiocytosis: Common hematopoietic origin for LCH-associated neurodegeneration and mass lesions.Authorship 8906714229749861Gutierrez AM, Robinson JO, Statham EE, Scollon S, Bergstrom KL, Slashinski MJ, Parsons DW, Plon SE, McGuire AL, Street RLPersonalized medicinePortero versus portador: Spanish interpretation of genomic terminology during whole exome sequencing results disclosure. Per Med. 2017 11; 14(6):503-514.Per Med2017-11-21T00:00:002017Portero versus portador: Spanish interpretation of genomic terminology during whole exome sequencing results disclosure.D014972Disorders23380.949505Xanthogranuloma, JuvenileAuthorship 9279027Authorship 93482211Authorship 93640626Authorship 9380208D006646Disorders832600.770818Histiocytosis, Langerhans-Cell30193136Amendola LM, Berg JS, Horowitz CR, Angelo F, Bensen JT, Biesecker BB, Biesecker LG, Cooper GM, East K, Filipski K, Fullerton SM, Gelb BD, Goddard KAB, Hailu B, Hart R, Hassmiller-Lich K, Joseph G, Kenny EE, Koenig BA, Knight S, Kwok PY, Lewis KL, McGuire AL, Norton ME, Ou J, Parsons DW, Powell BC, Risch N, Robinson M, Rini C, Scollon S, Slavotinek AM, Veenstra DL, Wasserstein MP, Wilfond BS, Hindorff LA, CSER consortium, Plon SE, Jarvik GPAmerican journal of human geneticsThe Clinical Sequencing Evidence-Generating Research Consortium: Integrating Genomic Sequencing in Diverse and Medically Underserved Populations. Am J Hum Genet. 2018 09 06; 103(3):319-327.Am J Hum Genet2018-09-06T00:00:002018The Clinical Sequencing Evidence-Generating Research Consortium: Integrating Genomic Sequencing in Diverse and Medically Underserved Populations.30482469Scollon S, Majumder MA, Bergstrom K, Wang T, McGuire AL, Robinson JO, Gutierrez AM, Lee CH, Hilsenbeck SG, Plon SE, Parsons DW, Street RLPatient education and counselingExome sequencing disclosures in pediatric cancer care: Patterns of communication among oncologists, genetic counselors, and parents. Patient Educ Couns. 2019 04; 102(4):680-686.Patient Educ Couns2018-11-12T00:00:002018Exome sequencing disclosures in pediatric cancer care: Patterns of communication among oncologists, genetic counselors, and parents.30581014Gutierrez AM, Statham EE, Robinson JO, Slashinski MJ, Scollon S, Bergstrom KL, Street RL, Parsons DW, Plon SE, McGuire ALPatient education and counselingAgents of empathy: How medical interpreters bridge sociocultural gaps in genomic sequencing disclosures with Spanish-speaking families. Patient Educ Couns. 2019 05; 102(5):895-901.Patient Educ Couns2018-12-10T00:00:002018Agents of empathy: How medical interpreters bridge sociocultural gaps in genomic sequencing disclosures with Spanish-speaking families.D008527Disorders1705380.66774Medulloblastoma2022-05-31NIHPLON, SHARON E.2011-12-05Evaluating utility and improving implementation of genomic sequencing for pediatric cancer patients in the diverse population and healthcare settings of Texas: The KidsCanSeq StudyU01HG006485Co-Principal InvestigatorDepartment of PediatricsDepartment of Molecular & Human GeneticsDepartment of Pathology & ImmunologyHuman Genome Sequencing CenterHuman Genome Sequencing CenterMolecular & Human GeneticsPathologyPediatrics-OncologyBaylor College of Medicine111groups1.28880.00385902449research areas3.130980.032573117coauthor of76.320816.840459similar to11106selected publicationsDOLORESLOPEZ-TERRADADOLORES LOPEZ-TERRADA0.000000000000000.000000000000002067LOPEZ-TERRADA, DOLORESProfessorMARIAGRAMATGESMARIA GRAMATGES0.000000000000000.000000000000001586GRAMATGES, MARIAProfessorHEIDIRUSSELLHEIDI RUSSELL0.000000000000000.000000000000002613RUSSELL, HEIDIAdjunct Associate ProfessorJAMESLUPSKIJAMES LUPSKI29.71073630000000-95.396604500000003140LUPSKI, JAMESProfessorANGSHUMOYROYANGSHUMOY ROY0.000000000000000.000000000000004422ROY, ANGSHUMOYAssociate ProfessorMICHELEREDELLMICHELE REDELL0.000000000000000.000000000000002094REDELL, MICHELEAssociate ProfessorMARGARETPARMETERMARGARET PARMETER0.000000000000000.00000000000000278PARMETER, MARGARETInstructorSHARONPLONSHARON PLON0.000000000000000.000000000000003410PLON, SHARON0000-0002-9626-0936ProfessorEVELINEBARBIERIEVELINE BARBIERI0.000000000000000.000000000000004792BARBIERI, EVELINEAssociate ProfessorCARLALLENCARL ALLEN0.000000000000000.00000000000000909ALLEN, CARL0000-0002-6625-739XProfessorAuthorship 944338930977242Haines K, Sarabia SF, Alvarez KR, Tomlinson G, Vasudevan SA, Heczey AA, Roy A, Finegold MJ, Parsons DW, Plon SE, L?pez-Terrada DPediatric blood & cancerCharacterization of pediatric hepatocellular carcinoma reveals genomic heterogeneity and diverse signaling pathway activation. Pediatr Blood Cancer. 2019 07; 66(7):e27745.Pediatr Blood Cancer2019-04-11T00:00:002019Characterization of pediatric hepatocellular carcinoma reveals genomic heterogeneity and diverse signaling pathway activation.Authorship 106474231186522Malek J, Pereira S, Robinson JO, Gutierrez AM, Slashinski MJ, Parsons DW, Plon SE, McGuire ALGenetics in medicine : official journal of the American College of Medical GeneticsResponsibility, culpability, and parental views on genomic testing for seriously ill children. Genet Med. 2019 12; 21(12):2791-2797.Genet Med2019-06-12T00:00:002019Responsibility, culpability, and parental views on genomic testing for seriously ill children.Dr. Shaulsky's GroupMember31624068Lindsay H, Scollon S, Reuther J, Voicu H, Rednam SP, Lin FY, Fisher KE, Chintagumpala M, Adesina AM, Parsons DW, Plon SE, Roy ACold Spring Harbor molecular case studiesGermline POLE mutation in a child with hypermutated medulloblastoma and features of constitutional mismatch repair deficiency. Cold Spring Harb Mol Case Stud. 2019 10; 5(5).Cold Spring Harb Mol Case Stud2019-10-23T00:00:002019Germline POLE mutation in a child with hypermutated medulloblastoma and features of constitutional mismatch repair deficiency.31645346Hassan M, Butler E, Wilson R, Roy A, Zheng Y, Liem P, Rakheja D, Pavlick D, Young LL, Rosenzweig M, Erlich R, Ali SM, Leavey PJ, Parsons DW, Skapek SX, Laetsch TWCold Spring Harbor molecular case studiesNovel PDGFRB rearrangement in multifocal infantile myofibromatosis is tumorigenic and sensitive to imatinib. Cold Spring Harb Mol Case Stud. 2019 10; 5(5).Cold Spring Harb Mol Case Stud2019-10-23T00:00:002019Novel PDGFRB rearrangement in multifocal infantile myofibromatosis is tumorigenic and sensitive to imatinib.true1ProfessorProfessortrue1Associate ProfessorAssociate Professor31886451Malek J, Slashinski MJ, Robinson JO, Gutierrez AM, Parsons DW, Plon SE, McCullough LB, McGuire ALJCO precision oncologyParental Perspectives on Whole Exome Sequencing in Pediatric Cancer: A Typology of Perceived Utility. JCO Precis Oncol. 2017; 1.JCO Precis Oncol2017-05-31T00:00:002017Parental Perspectives on Whole Exome Sequencing in Pediatric Cancer: A Typology of Perceived Utility.Authorship 9792761732179872Burns AM, Ackerman KG, Thammasitboon S, Rassbach CE, Ward MA, Blankenburg RL, Forster CS, McPhillips HA, Wenger TL, Powell WT, Heyman MB, Hogarty MD, Boyer D, Hostetter M, Weiss P, Nguyen ST, Parsons DW, Moore DJ, Byrne BJ, French AR, Orange JSPediatric researchFixing the leaky pipeline: identifying solutions for improving pediatrician-scientist training during pediatric residency. Pediatr Res. 2020 08; 88(2):163-167.Pediatr Res2020-03-16T00:00:002020Fixing the leaky pipeline: identifying solutions for improving pediatrician-scientist training during pediatric residency.Authorship 982570224976606Kragh JF, Steinbaugh J, Parsons DL, Mabry RL, Kheirabadi BS, Dubick MAThe American journal of emergency medicineA manikin model for study of wound-packing interventions to control out-of-hospital hemorrhage. Am J Emerg Med. 2014 Sep; 32(9):1130-1.Am J Emerg Med2014-05-21T00:00:002014A manikin model for study of wound-packing interventions to control out-of-hospital hemorrhage.Authorship 989288832393959Goldman S, Pollack IF, Jakacki RI, Billups CA, Poussaint TY, Adesina AM, Panigrahy A, Parsons DW, Broniscer A, Robinson GW, Robison NJ, Partap S, Kilburn LB, Onar-Thomas A, Dunkel IJ, Fouladi MNeuro-oncologyPhase II study of peginterferon alpha-2b for patients with unresectable or recurrent craniopharyngiomas: a Pediatric Brain Tumor Consortium report. Neuro Oncol. 2020 11 26; 22(11):1696-1704.Neuro Oncol2020-11-26T00:00:002020Phase II study of peginterferon alpha-2b for patients with unresectable or recurrent craniopharyngiomas: a Pediatric Brain Tumor Consortium report.Authorship 9948082Authorship 99480914Authorship 99481010Authorship 9948116Authorship 99481218Authorship 994813531757314Vo KT, Parsons DW, Seibel NLSurgical oncology clinics of North AmericaPrecision Medicine in Pediatric Oncology. Surg Oncol Clin N Am. 2020 01; 29(1):63-72.Surg Oncol Clin N Am2019-10-29T00:00:002019Precision Medicine in Pediatric Oncology.30805642Miklja Z, Pasternak A, Stallard S, Nicolaides T, Kline-Nunnally C, Cole B, Beroukhim R, Bandopadhayay P, Chi S, Ramkissoon SH, Mullan B, Bruzek AK, Gauthier A, Garcia T, Atchison C, Marini B, Fouladi M, Parsons DW, Leary S, Mueller S, Ligon KL, Koschmann CNeuro-oncologyMolecular profiling and targeted therapy in pediatric gliomas: review and consensus recommendations. Neuro Oncol. 2019 08 05; 21(8):968-980.Neuro Oncol2019-08-05T00:00:002019Molecular profiling and targeted therapy in pediatric gliomas: review and consensus recommendations.true1ProfessorProfessor32821910Chandramohan R, Kakkar N, Roy A, Parsons DWBioinformatics (Oxford, England)reconCNV: interactive visualization of copy number data from high-throughput sequencing. Bioinformatics. 2021 05 23; 37(8):1164-1167.Bioinformatics2021-05-23T00:00:002021reconCNV: interactive visualization of copy number data from high-throughput sequencing.Authorship 9980031232843649Manica M, Kim HR, Mathis R, Chouvarine P, Rutishauser D, De Vargas Roditi L, Szalai B, Wagner U, Oehl K, Saba K, Pati A, Saez-Rodriguez J, Roy A, Parsons DW, Wild PJ, Mart?nez MR, Sumazin PNPJ systems biology and applicationsInferring clonal composition from multiple tumor biopsies. NPJ Syst Biol Appl. 2020 08 25; 6(1):27.NPJ Syst Biol Appl2020-08-25T00:00:002020Inferring clonal composition from multiple tumor biopsies.32876512Yost CM, Gaikwad AS, Parsons DW, Rabin KR, Gant VU, Fisher KE, Marcogliese AN, Schafer ESLeukemia & lymphomaAberrant leukemia-associated immunophenotype as potential harbinger of lineage switch in KMT2A-rearranged leukemia: a case series. Leuk Lymphoma. 2020 12; 61(14):3515-3518.Leuk Lymphoma2020-09-02T00:00:002020Aberrant leukemia-associated immunophenotype as potential harbinger of lineage switch in KMT2A-rearranged leukemia: a case series.http://www.texaschildrens.org/departments/cancer-genetics-clinic/our-teamTexas Children's Cancer Genetics Clinichttps://www.bcm.edu/people-search/sharon-plon-28865My Research Sitesplon33009870Potter SL, Reuther J, Chandramohan R, Gandhi I, Hollingsworth F, Sayeed H, Voicu H, Kakkar N, Baksi KS, Sarabia SF, Lopez ME, Chelius DC, Athanassaki ID, Mahajan P, Venkatramani R, Quintanilla NM, Lopez-Terrada DH, Roy A, Parsons DWPediatric blood & cancerIntegrated DNA and RNA sequencing reveals targetable alterations in metastatic pediatric papillary thyroid carcinoma. Pediatr Blood Cancer. 2021 01; 68(1):e28741.Pediatr Blood Cancer2020-10-03T00:00:002020Integrated DNA and RNA sequencing reveals targetable alterations in metastatic pediatric papillary thyroid carcinoma.33067228Li J, Zhao S, Lee M, Yin Y, Li J, Zhou Y, Ballester LY, Esquenazi Y, Dashwood RH, Davies PJA, Parsons DW, Li XN, Huang Y, Sun DScience advancesReliable tumor detection by whole-genome methylation sequencing of cell-free DNA in cerebrospinal fluid of pediatric medulloblastoma. Sci Adv. 2020 10; 6(42).Sci Adv2020-10-16T00:00:002020Reliable tumor detection by whole-genome methylation sequencing of cell-free DNA in cerebrospinal fluid of pediatric medulloblastoma.Authorship 10141283133741710Arabzade A, Zhao Y, Varadharajan S, Chen HC, Jessa S, Rivas B, Stuckert AJ, Solis M, Kardian A, Tlais D, Golbourn BJ, Stanton AJ, Chan YS, Olson C, Karlin KL, Kong K, Kupp R, Hu B, Injac SG, Ngo M, Wang PR, De Le?n LA, Sahm F, Kawauchi D, Pfister SM, Lin CY, Hodges HC, Singh I, Westbrook TF, Chintagumpala MM, Blaney SM, Parsons DW, Pajtler KW, Agnihotri S, Gilbertson RJ, Yi J, Jabado N, Kleinman CL, Bertrand KC, Deneen B, Mack SCCancer discoveryZFTA-RELA Dictates Oncogenic Transcriptional Programs to Drive Aggressive Supratentorial Ependymoma. Cancer Discov. 2021 09; 11(9):2200-2215.Cancer Discov2021-03-19T00:00:002021ZFTA-RELA Dictates Oncogenic Transcriptional Programs to Drive Aggressive Supratentorial Ependymoma.Authorship 121632834086347Ting MA, Reuther J, Chandramohan R, Voicu H, Gandhi I, Liu M, Cortes-Santiago N, Foster JH, Hicks J, Nuchtern J, Scollon S, Plon SE, Chintagumpala M, Rainusso N, Roy A, Parsons DWThe Journal of pathologyGenomic analysis and preclinical xenograft model development identify potential therapeutic targets for MYOD1-mutant soft-tissue sarcoma of childhood. J Pathol. 2021 09; 255(1):52-61.J Pathol2021-07-07T00:00:002021Genomic analysis and preclinical xenograft model development identify potential therapeutic targets for MYOD1-mutant soft-tissue sarcoma of childhood.34207141Hsu RL, Gutierrez AM, Schellhammer SK, Robinson JO, Scollon S, Street RL, Salisbury AN, Pereira S, Plon SE, Malek J, Parsons DW, McGuire ALJournal of personalized medicinePediatric Oncologists' Experiences Returning and Incorporating Genomic Sequencing Results into Cancer Care. J Pers Med. 2021 Jun 18; 11(6).J Pers Med2021-06-18T00:00:002021Pediatric Oncologists' Experiences Returning and Incorporating Genomic Sequencing Results into Cancer Care.Authorship 10256221734280401Burns AM, Moore DJ, Forster CS, Powell W, Thammasitboon S, Hostetter MK, Weiss P, Boyer D, Ward MA, Blankenburg R, Heyman MB, Rassbach CE, McPhillips H, French A, Nguyen S, Byrne BJ, Parsons DW, Gonzalez F, Nowalk AJ, Ho J, Kumar S, Orange JS, Ackerman KGThe Journal of pediatricsPhysician-Scientist Training and Programming in Pediatric Residency Programs: A National Survey. J Pediatr. 2022 02; 241:5-9.e3.J Pediatr2021-07-16T00:00:002021Physician-Scientist Training and Programming in Pediatric Residency Programs: A National Survey.Authorship 102602611Authorship 102602716Authorship 102602811Authorship 102602919Authorship 10260303Authorship 1026031434651095Mangum R, Reuther J, Bertrand KC, Chandramohan R, Kukreja MK, Paulino AC, Muzny D, Hu J, Gibbs RA, Curry DJ, Malbari F, Chintagumpala MM, Adesina AM, Fisher KE, Mack SC, Plon SE, Roy A, Parsons DW, Lin FYJCO precision oncologyDurable Response to Larotrectinib in a Child With Histologic Diagnosis of Recurrent Disseminated Ependymoma Discovered to Harbor an NTRK2 Fusion: The Impact of Integrated Genomic Profiling. JCO Precis Oncol. 2021; 5.JCO Precis Oncol2021-07-28T00:00:002021Durable Response to Larotrectinib in a Child With Histologic Diagnosis of Recurrent Disseminated Ependymoma Discovered to Harbor an NTRK2 Fusion: The Impact of Integrated Genomic Profiling.35026696Garcia A, Desrosiers L, Scollon S, Gruner S, Reuther J, Gandhi I, Patil N, Fuller MY, Dai H, Muzny D, Gibbs RA, Bercaw-Pratt JL, Rao SL, Rainusso N, Fisher KE, Lin FY, Plon SE, Parsons DW, Roy ACancer geneticsDistinct somatic DICER1 hotspot mutations in three metachronous ovarian Sertoli-Leydig cell tumors in a patient with DICER1 syndrome. Cancer Genet. 2022 04; 262-263:53-56.Cancer Genet2022-01-05T00:00:002022Distinct somatic DICER1 hotspot mutations in three metachronous ovarian Sertoli-Leydig cell tumors in a patient with DICER1 syndrome.35182954Kogiso M, Qi L, Du Y, Braun FK, Zhang H, Huang LF, Guo L, Huang Y, Teo WY, Lindsay H, Zhao S, Injac SG, Liu Z, Mehta V, Tran D, Li F, Baxter PA, Su JM, Perlaky L, Parsons DW, Chintagumpala M, Adesina A, Song Y, Li XNTranslational oncologySynergistic anti-tumor efficacy of mutant isocitrate dehydrogenase 1 inhibitor SYC-435 with standard therapy in patient-derived xenograft mouse models of glioma. Transl Oncol. 2022 Apr; 18:101368.Transl Oncol2022-02-16T00:00:002022Synergistic anti-tumor efficacy of mutant isocitrate dehydrogenase 1 inhibitor SYC-435 with standard therapy in patient-derived xenograft mouse models of glioma.35363510Eckstein OS, Allen CE, Williams PM, Roy-Chowdhuri S, Patton DR, Coffey B, Reid JM, Piao J, Saguilig L, Alonzo TA, Berg SL, Ramirez NC, Jaju A, Mhlanga J, Fox E, Hawkins DS, Mooney MM, Takebe N, Tricoli JV, Janeway KA, Seibel NL, Parsons DWJournal of clinical oncology : official journal of the American Society of Clinical OncologyPhase II Study of Selumetinib in Children and Young Adults With Tumors Harboring Activating Mitogen-Activated Protein Kinase Pathway Genetic Alterations: Arm E of the NCI-COG Pediatric MATCH Trial. J Clin Oncol. 2022 07 10; 40(20):2235-2245.J Clin Oncol2022-04-01T00:00:002022Phase II Study of Selumetinib in Children and Young Adults With Tumors Harboring Activating Mitogen-Activated Protein Kinase Pathway Genetic Alterations: Arm E of the NCI-COG Pediatric MATCH Trial.35353553Parsons DW, Janeway KA, Patton DR, Winter CL, Coffey B, Williams PM, Roy-Chowdhuri S, Tsongalis GJ, Routbort M, Ramirez NC, Saguilig L, Piao J, Alonzo TA, Berg SL, Fox E, Hawkins DS, Abrams JS, Mooney M, Takebe N, Tricoli JV, Seibel NL, NCI-COG Pediatric MATCH TeamJournal of clinical oncology : official journal of the American Society of Clinical OncologyActionable Tumor Alterations and Treatment Protocol Enrollment of Pediatric and Young Adult Patients With Refractory Cancers in the National Cancer Institute-Children's Oncology Group Pediatric MATCH Trial. J Clin Oncol. 2022 07 10; 40(20):2224-2234.J Clin Oncol2022-03-30T00:00:002022Actionable Tumor Alterations and Treatment Protocol Enrollment of Pediatric and Young Adult Patients With Refractory Cancers in the National Cancer Institute-Children's Oncology Group Pediatric MATCH Trial.Authorship 10431339Authorship 104313422Authorship 10431351Authorship 104313620Authorship 10431372Authorship 104313818Authorship 10431391835487348Chandramohan R, Reuther J, Gandhi I, Voicu H, Alvarez KR, Plon SE, Lopez-Terrada DH, Fisher KE, Parsons DW, Roy AThe Journal of molecular diagnostics : JMDA Validation Framework for Somatic Copy Number Detection in Targeted Sequencing Panels. J Mol Diagn. 2022 07; 24(7):760-774.J Mol Diagn2022-04-26T00:00:002022A Validation Framework for Somatic Copy Number Detection in Targeted Sequencing Panels.35178549Mangum R, Parsons DWNeuro-oncologyTRK inhibition for pediatric and adult central nervous system tumors: Early promise and future questions. Neuro Oncol. 2022 06 01; 24(6):1008-1009.Neuro Oncol2022-06-01T00:00:002022TRK inhibition for pediatric and adult central nervous system tumors: Early promise and future questions.Authorship 1047261721455908Kragh JF, O'Neill ML, Beebe DF, Fox CJ, Beekley AC, Cain JS, Parsons DL, Mabry RL, Blackbourne LHJournal of special operations medicine : a peer reviewed journal for SOF medical professionalsSurvey of the indications for use of emergency tourniquets. J Spec Oper Med. 2011; 11(1):30-34.J Spec Oper Med2011-01-01T00:00:002011Survey of the indications for use of emergency tourniquets.35713195Scollon S, Eldomery MK, Reuther J, Lin FY, Potter SL, Desrosiers L, McClain KL, Smith V, Su JM, Venkatramani R, Hu J, Korchina V, Zarrin-Khameh N, Gibbs RA, Muzny DM, Eng C, Roy A, Parsons DW, Plon SEPediatric blood & cancerClinical and molecular features of pediatric cancer patients with Lynch syndrome. Pediatr Blood Cancer. 2022 11; 69(11):e29859.Pediatr Blood Cancer2022-06-30T00:00:002022Clinical and molecular features of pediatric cancer patients with Lynch syndrome.Authorship 104828618true1Assistant ProfessorAssistant ProfessorAuthorship 121873Authorship 105724728Authorship 106044828Authorship 10604624836550163Zhao S, Li J, Zhang H, Qi L, Du Y, Kogiso M, Braun FK, Xiao S, Huang Y, Li J, Teo WY, Lindsay H, Baxter P, Su JMF, Adesina A, Laczik M, Genevini P, Veillard AC, Schvartzman S, Berguet G, Ding SR, Du L, Stephan C, Yang J, Davies PJA, Lu X, Chintagumpala M, Parsons DW, Perlaky L, Xia YF, Man TK, Huang Y, Sun D, Li XNNature communicationsPublisher Correction: Epigenetic alterations of repeated relapses in patient-matched childhood ependymomas. Nat Commun. 2022 Dec 22; 13(1):7871.Nat Commun2022-12-22T00:00:002022Publisher Correction: Epigenetic alterations of repeated relapses in patient-matched childhood ependymomas.36595372Gutierrez AM, Robinson JO, Raesz-Martinez R, Canfield I, Majumder MA, Scollon S, Desrosiers LR, Hsu RL, Allen-Rhoades W, Parsons DW, Plon SE, McGuire AL, Malek JJournal of adolescent and young adult oncologyViews of Adolescents and Young Adults with Cancer and Their Oncologists Toward Patients' Participation in Genomic Research. J Adolesc Young Adult Oncol. 2023 10; 12(5):773-781.J Adolesc Young Adult Oncol2023-01-02T00:00:002023Views of Adolescents and Young Adults with Cancer and Their Oncologists Toward Patients' Participation in Genomic Research.36335125Zhao S, Li J, Zhang H, Qi L, Du Y, Kogiso M, Braun FK, Xiao S, Huang Y, Li J, Teo WY, Lindsay H, Baxter P, Su JMF, Adesina A, Laczik M, Genevini P, Veillard AC, Schvartzman S, Berguet G, Ding SR, Du L, Stephan C, Yang J, Davies PJA, Lu X, Chintagumpala M, Parsons DW, Perlaky L, Xia YF, Man TK, Huang Y, Sun D, Li XNNature communicationsEpigenetic Alterations of Repeated Relapses in Patient-matched Childhood Ependymomas. Nat Commun. 2022 11 05; 13(1):6689.Nat Commun2022-11-05T00:00:002022Epigenetic Alterations of Repeated Relapses in Patient-matched Childhood Ependymomas.36335802Lilly JV, Rokita JL, Mason JL, Patton T, Stefankiewiz S, Higgins D, Trooskin G, Larouci CA, Arya K, Appert E, Heath AP, Zhu Y, Brown MA, Zhang B, Farrow BK, Robins S, Morgan AM, Nguyen TQ, Frenkel E, Lehmann K, Drake E, Sullivan C, Plisiewicz A, Coleman N, Patterson L, Koptyra M, Helili Z, Van Kuren N, Young N, Kim MC, Friedman C, Lubneuski A, Blackden C, Williams M, Baubet V, Tauhid L, Galanaugh J, Boucher K, Ijaz H, Cole KA, Choudhari N, Santi M, Moulder RW, Waller J, Rife W, Diskin SJ, Mateos M, Parsons DW, Pollack IF, Goldman S, Leary S, Caporalini C, Buccoliero AM, Scagnet M, Haussler D, Hanson D, Firestein R, Cain J, Phillips JJ, Gupta N, Mueller S, Grant G, Monje-Deisseroth M, Partap S, Greenfield JP, Hashizume R, Smith A, Zhu S, Johnston JM, Fangusaro JR, Miller M, Wood MD, Gardner S, Carter CL, Prolo LM, Pisapia J, Pehlivan K, Franson A, Niazi T, Rubin J, Abdelbaki M, Ziegler DS, Lindsay HB, Stucklin AG, Gerber N, Vaske OM, Quinsey C, Rood BR, Nazarian J, Raabe E, Jackson EM, Stapleton S, Lober RM, Kram DE, Koschmann C, Storm PB, Lulla RR, Prados M, Resnick AC, Waanders AJNeoplasia (New York, N.Y.)The children's brain tumor network (CBTN) - Accelerating research in pediatric central nervous system tumors through collaboration and open science. Neoplasia. 2023 01; 35:100846.Neoplasia2022-11-03T00:00:002022The children's brain tumor network (CBTN) - Accelerating research in pediatric central nervous system tumors through collaboration and open science.true1ProfessorProfessor2ProfessorProfessor3ProfessorProfessorAuthorship 106559710Authorship 10717452Authorship 107174625Authorship 10717471437366551Mangum R, Reuther J, Sen Baksi K, Gandhi I, Zabriskie RC, Recinos A, Raesz-Martinez R, Lin FY, Potter SL, Sher AC, Kralik SF, Mohila CA, Chintagumpala MM, Muzny D, Hu J, Gibbs RA, Fisher KE, Bernini JC, Gill J, Griffin TC, Tomlinson GE, Vallance KL, Plon SE, Roy A, Parsons DWPediatric hematology and oncologyCirculating tumor DNA sequencing of pediatric solid and brain tumor patients: An institutional feasibility study. Pediatr Hematol Oncol. 2023; 40(8):719-738.Pediatr Hematol Oncol2023-06-27T00:00:002023Circulating tumor DNA sequencing of pediatric solid and brain tumor patients: An institutional feasibility study.37430453Fox E, Parsons DW, Weigel BJ, Developmental Therapeutics CommitteePediatric blood & cancerChildren's Oncology Group's 2023 blueprint for research: Developmental therapeutics. Pediatr Blood Cancer. 2023 09; 70 Suppl 6:e30563.Pediatr Blood Cancer2023-07-10T00:00:002023Children's Oncology Group's 2023 blueprint for research: Developmental therapeutics.37228094Chi SN, Yi JS, Williams PM, Roy-Chowdhuri S, Patton DR, Coffey BD, Reid JM, Piao J, Saguilig L, Alonzo TA, Berg SL, Ramirez NC, Jaju A, Mhlanga JC, Fox E, Hawkins DS, Mooney MM, Takebe N, Tricoli JV, Janeway KA, Seibel NL, Parsons DWJournal of the National Cancer InstituteTazemetostat for tumors harboring SMARCB1/SMARCA4 or EZH2 alterations: results from NCI-COG pediatric MATCH APEC1621C. J Natl Cancer Inst. 2023 11 08; 115(11):1355-1363.J Natl Cancer Inst2023-11-08T00:00:002023Tazemetostat for tumors harboring SMARCB1/SMARCA4 or EZH2 alterations: results from NCI-COG pediatric MATCH APEC1621C.https://www.texaschildrens.org/find-a-doctor/sharon-e-plon-md-phd-facmgTexas Children's Hospital Profiletrue1Associate ProfessorAssociate Professortrue1Adjunct Associate ProfessorAdjunct Associate Professortrue1ProfessorProfessorAuthorship 1084165537961416Hirschi OR, Felker SA, Rednam SP, Vallance KL, Parsons DW, Roy A, Cooper GM, Plon SEmedRxiv : the preprint server for health sciencesCombined Bioinformatic and Splicing Analysis of Likely Benign Intronic and Synonymous Variants Reveals Evidence for Pathogenicity. medRxiv. 2023 Nov 01.medRxiv2023-11-01T00:00:002023Combined Bioinformatic and Splicing Analysis of Likely Benign Intronic and Synonymous Variants Reveals Evidence for Pathogenicity.Authorship 166352Authorship 10869861338225886Vuocolo B, Gutierrez AM, Robinson JO, Recinos AM, Desrosiers LR, Majumder MA, Bernini JC, Gill J, Griffin T, Tomlinson GE, Vallance K, McGuire AL, Parsons DW, Plon SE, Scollon SJournal of genetic counselingFamilies' experiences accessing care after genomic sequencing in the pediatric cancer context: "It's just been a big juggle". J Genet Couns. 2024 Jan 15.J Genet Couns2024-01-15T00:00:002024Families' experiences accessing care after genomic sequencing in the pediatric cancer context: "It's just been a big juggle".true1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessorAuthorship 234062Authorship 320542Authorship 388322Authorship 411141Authorship 478921Authorship 437781Authorship 149022124958819Parsons DW, Roy A, Plon SE, Roychowdhury S, Chinnaiyan AMJournal of clinical oncology : official journal of the American Society of Clinical OncologyClinical tumor sequencing: an incidental casualty of the American College of Medical Genetics and Genomics recommendations for reporting of incidental findings. J Clin Oncol. 2014 Jul 20; 32(21):2203-5.J Clin Oncol2014-06-23T00:00:002014Clinical tumor sequencing: an incidental casualty of the American College of Medical Genetics and Genomics recommendations for reporting of incidental findings.Authorship 81255625202140Chakraborty R, Hampton OA, Shen X, Simko SJ, Shih A, Abhyankar H, Lim KP, Covington KR, Trevino L, Dewal N, Muzny DM, Doddapaneni H, Hu J, Wang L, Lupo PJ, Hicks MJ, Bonilla DL, Dwyer KC, Berres ML, Poulikakos PI, Merad M, McClain KL, Wheeler DA, Allen CE, Parsons DWBloodMutually exclusive recurrent somatic mutations in MAP2K1 and BRAF support a central role for ERK activation in LCH pathogenesis. Blood. 2014 Nov 06; 124(19):3007-15.Blood2014-09-08T00:00:002014Mutually exclusive recurrent somatic mutations in MAP2K1 and BRAF support a central role for ERK activation in LCH pathogenesis.Authorship 605119Authorship 1530761425317207Scollon S, Bergstrom K, Kerstein RA, Wang T, Hilsenbeck SG, Ramamurthy U, Gibbs RA, Eng CM, Chintagumpala MM, Berg SL, McCullough LB, McGuire AL, Plon SE, Parsons DWGenome medicineObtaining informed consent for clinical tumor and germline exome sequencing of newly diagnosed childhood cancer patients. Genome Med. 2014; 6(9):69.Genome Med2014-09-17T00:00:002014Obtaining informed consent for clinical tumor and germline exome sequencing of newly diagnosed childhood cancer patients.Authorship 921936Authorship 15341925Authorship 73563Authorship 15581814