Connection

CHAD CREIGHTON to Gene Expression Profiling

This is a "connection" page, showing publications CHAD CREIGHTON has written about Gene Expression Profiling.
Connection Strength

5.700
  1. An essential gene signature of breast cancer metastasis reveals targetable pathways. Breast Cancer Res. 2024 06 12; 26(1):98.
    View in: PubMed
    Score: 0.525
  2. Molecular Correlates of Metastasis by Systematic Pan-Cancer Analysis Across The Cancer Genome Atlas. Mol Cancer Res. 2019 02; 17(2):476-487.
    View in: PubMed
    Score: 0.356
  3. Molecular classification and drug response prediction in cancer. Curr Drug Targets. 2012 Nov; 13(12):1488-94.
    View in: PubMed
    Score: 0.235
  4. A gene transcription signature of obesity in breast cancer. Breast Cancer Res Treat. 2012 Apr; 132(3):993-1000.
    View in: PubMed
    Score: 0.215
  5. Proteomic and transcriptomic profiling reveals a link between the PI3K pathway and lower estrogen-receptor (ER) levels and activity in ER+ breast cancer. Breast Cancer Res. 2010; 12(3):R40.
    View in: PubMed
    Score: 0.199
  6. Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features. Proc Natl Acad Sci U S A. 2009 Aug 18; 106(33):13820-5.
    View in: PubMed
    Score: 0.188
  7. Expression profiling of microRNAs by deep sequencing. Brief Bioinform. 2009 Sep; 10(5):490-7.
    View in: PubMed
    Score: 0.183
  8. A bioinformatics tool for linking gene expression profiling results with public databases of microRNA target predictions. RNA. 2008 Nov; 14(11):2290-6.
    View in: PubMed
    Score: 0.177
  9. Insulin-like growth factor-I activates gene transcription programs strongly associated with poor breast cancer prognosis. J Clin Oncol. 2008 Sep 01; 26(25):4078-85.
    View in: PubMed
    Score: 0.176
  10. Molecular profiles of progesterone receptor loss in human breast tumors. Breast Cancer Res Treat. 2009 Mar; 114(2):287-99.
    View in: PubMed
    Score: 0.172
  11. Multiple oncogenic pathway signatures show coordinate expression patterns in human prostate tumors. PLoS One. 2008 Mar 19; 3(3):e1816.
    View in: PubMed
    Score: 0.171
  12. A gene transcription signature of the Akt/mTOR pathway in clinical breast tumors. Oncogene. 2007 Jul 12; 26(32):4648-55.
    View in: PubMed
    Score: 0.157
  13. When will tumor gene expression profiling be incorporated into clinical breast cancer decision making? Breast Cancer Res. 2006; 8(4):302.
    View in: PubMed
    Score: 0.146
  14. Gene expression patterns define pathways correlated with loss of differentiation in lung adenocarcinomas. FEBS Lett. 2003 Apr 10; 540(1-3):167-70.
    View in: PubMed
    Score: 0.121
  15. Mining gene expression databases for association rules. Bioinformatics. 2003 Jan; 19(1):79-86.
    View in: PubMed
    Score: 0.119
  16. Making sense of microarray data to classify cancer. Pharmacogenomics J. 2003; 3(6):308-11.
    View in: PubMed
    Score: 0.119
  17. Gene Expression Profiles in Cancers and Their Therapeutic Implications. Cancer J. 2023 Jan-Feb 01; 29(1):9-14.
    View in: PubMed
    Score: 0.119
  18. Global molecular alterations involving recurrence or progression of pediatric brain tumors. Neoplasia. 2022 01; 24(1):22-33.
    View in: PubMed
    Score: 0.110
  19. Constitutive expression of progesterone receptor isoforms promotes the development of hormone-dependent ovarian neoplasms. Sci Signal. 2020 10 06; 13(652).
    View in: PubMed
    Score: 0.102
  20. Pan-cancer molecular subtypes revealed by mass-spectrometry-based proteomic characterization of more than 500 human cancers. Nat Commun. 2019 12 12; 10(1):5679.
    View in: PubMed
    Score: 0.096
  21. Pan-Cancer Molecular Classes Transcending Tumor Lineage Across 32 Cancer Types, Multiple Data Platforms, and over 10,000 Cases. Clin Cancer Res. 2018 05 01; 24(9):2182-2193.
    View in: PubMed
    Score: 0.085
  22. Pan-urologic cancer genomic subtypes that transcend tissue of origin. Nat Commun. 2017 08 04; 8(1):199.
    View in: PubMed
    Score: 0.082
  23. A Pan-Cancer Proteogenomic Atlas of PI3K/AKT/mTOR Pathway Alterations. Cancer Cell. 2017 06 12; 31(6):820-832.e3.
    View in: PubMed
    Score: 0.080
  24. Multiplatform-based molecular subtypes of non-small-cell lung cancer. Oncogene. 2017 03; 36(10):1384-1393.
    View in: PubMed
    Score: 0.077
  25. Multilevel Genomics-Based Taxonomy of Renal Cell Carcinoma. Cell Rep. 2016 Mar 15; 14(10):2476-89.
    View in: PubMed
    Score: 0.074
  26. Effects of TP53 mutational status on gene expression patterns across 10 human cancer types. J Pathol. 2014 Apr; 232(5):522-33.
    View in: PubMed
    Score: 0.064
  27. Gene expression profile of A549 cells from tissue of 4D model predicts poor prognosis in lung cancer patients. Int J Cancer. 2014 Feb 15; 134(4):789-98.
    View in: PubMed
    Score: 0.062
  28. MicroRNA expression profiling reveals the potential function of microRNA-31 in chordomas. J Neurooncol. 2013 Nov; 115(2):143-51.
    View in: PubMed
    Score: 0.062
  29. Comprehensive molecular characterization of clear cell renal cell carcinoma. Nature. 2013 Jul 04; 499(7456):43-9.
    View in: PubMed
    Score: 0.061
  30. Prognostically relevant gene signatures of high-grade serous ovarian carcinoma. J Clin Invest. 2013 Jan; 123(1):517-25.
    View in: PubMed
    Score: 0.059
  31. Comprehensive molecular portraits of human breast tumours. Nature. 2012 Oct 04; 490(7418):61-70.
    View in: PubMed
    Score: 0.058
  32. Comprehensive genomic characterization of squamous cell lung cancers. Nature. 2012 Sep 27; 489(7417):519-25.
    View in: PubMed
    Score: 0.058
  33. Comprehensive molecular characterization of human colon and rectal cancer. Nature. 2012 Jul 18; 487(7407):330-7.
    View in: PubMed
    Score: 0.058
  34. Integrated genomic analyses of ovarian carcinoma. Nature. 2011 Jun 29; 474(7353):609-15.
    View in: PubMed
    Score: 0.053
  35. Molecular profiling uncovers a p53-associated role for microRNA-31 in inhibiting the proliferation of serous ovarian carcinomas and other cancers. Cancer Res. 2010 Mar 01; 70(5):1906-15.
    View in: PubMed
    Score: 0.049
  36. Genomic profiling of plasmablastic lymphoma using array comparative genomic hybridization (aCGH): revealing significant overlapping genomic lesions with diffuse large B-cell lymphoma. J Hematol Oncol. 2009 Nov 12; 2:47.
    View in: PubMed
    Score: 0.048
  37. Global gene expression analysis of reactive stroma in prostate cancer. Clin Cancer Res. 2009 Jun 15; 15(12):3979-89.
    View in: PubMed
    Score: 0.046
  38. Genomic profiling of prostate cancers from African American men. Neoplasia. 2009 Mar; 11(3):305-12.
    View in: PubMed
    Score: 0.046
  39. Development of resistance to targeted therapies transforms the clinically associated molecular profile subtype of breast tumor xenografts. Cancer Res. 2008 Sep 15; 68(18):7493-501.
    View in: PubMed
    Score: 0.044
  40. Transcriptional response of the murine mammary gland to acute progesterone exposure. Endocrinology. 2008 Dec; 149(12):6236-50.
    View in: PubMed
    Score: 0.044
  41. Transcriptional profiling of non-small cell lung cancer cells with activating EGFR somatic mutations. PLoS One. 2007 Nov 21; 2(11):e1226.
    View in: PubMed
    Score: 0.042
  42. A gene transcription signature associated with hormone independence in a subset of both breast and prostate cancers. BMC Genomics. 2007 Jun 28; 8:199.
    View in: PubMed
    Score: 0.041
  43. Genes regulated by estrogen in breast tumor cells in vitro are similarly regulated in vivo in tumor xenografts and human breast tumors. Genome Biol. 2006; 7(4):R28.
    View in: PubMed
    Score: 0.037
  44. Molecular profiling of human prostate tissues: insights into gene expression patterns of prostate development during puberty. FASEB J. 2005 Feb; 19(2):243-5.
    View in: PubMed
    Score: 0.034
  45. Transcriptomic analyses of ovarian clear-cell carcinoma with concurrent endometriosis. Front Endocrinol (Lausanne). 2023; 14:1162786.
    View in: PubMed
    Score: 0.031
  46. Profiling of pathway-specific changes in gene expression following growth of human cancer cell lines transplanted into mice. Genome Biol. 2003; 4(7):R46.
    View in: PubMed
    Score: 0.031
  47. Expression of matrix metalloproteinase 9 (MMP-9/gelatinase B) in adenocarcinomas strongly correlated with expression of immune response genes. In Silico Biol. 2003; 3(3):301-11.
    View in: PubMed
    Score: 0.030
  48. UALCAN: An update to the integrated cancer data analysis platform. Neoplasia. 2022 03; 25:18-27.
    View in: PubMed
    Score: 0.028
  49. Contextual cues from cancer cells govern cancer-associated fibroblast heterogeneity. Cell Rep. 2021 04 20; 35(3):109009.
    View in: PubMed
    Score: 0.026
  50. A Role for Progesterone-Regulated sFRP4 Expression in Uterine Leiomyomas. J Clin Endocrinol Metab. 2017 09 01; 102(9):3316-3326.
    View in: PubMed
    Score: 0.021
  51. UALCAN: A Portal for Facilitating Tumor Subgroup Gene Expression and Survival Analyses. Neoplasia. 2017 Aug; 19(8):649-658.
    View in: PubMed
    Score: 0.020
  52. The SWI/SNF Protein PBRM1 Restrains VHL-Loss-Driven Clear Cell Renal Cell Carcinoma. Cell Rep. 2017 03 21; 18(12):2893-2906.
    View in: PubMed
    Score: 0.020
  53. Identification of microRNA profile specific to cancer stem-like cells directly isolated from human larynx cancer specimens. BMC Cancer. 2016 11 05; 16(1):853.
    View in: PubMed
    Score: 0.019
  54. An Integrated Metabolic Atlas of Clear Cell Renal Cell Carcinoma. Cancer Cell. 2016 Jan 11; 29(1):104-116.
    View in: PubMed
    Score: 0.018
  55. Uterine ALK3 is essential during the window of implantation. Proc Natl Acad Sci U S A. 2016 Jan 19; 113(3):E387-95.
    View in: PubMed
    Score: 0.018
  56. HDAC Inhibition for the Treatment of Epithelioid Sarcoma: Novel Cross Talk Between Epigenetic Components. Mol Cancer Res. 2016 Jan; 14(1):35-43.
    View in: PubMed
    Score: 0.018
  57. Insights Into SMAD4 Loss in Pancreatic Cancer From Inducible Restoration of TGF-? Signaling. Mol Endocrinol. 2015 Oct; 29(10):1440-53.
    View in: PubMed
    Score: 0.018
  58. Circulating and disseminated tumor cells from breast cancer patient-derived xenograft-bearing mice as a novel model to study metastasis. Breast Cancer Res. 2015 Jan 09; 17:3.
    View in: PubMed
    Score: 0.017
  59. The Cancer Genome Atlas Pan-Cancer analysis project. Nat Genet. 2013 Oct; 45(10):1113-20.
    View in: PubMed
    Score: 0.016
  60. A dosage-dependent pleiotropic role of Dicer in prostate cancer growth and metastasis. Oncogene. 2014 Jun 12; 33(24):3099-108.
    View in: PubMed
    Score: 0.015
  61. MLH1-silenced and non-silenced subgroups of hypermutated colorectal carcinomas have distinct mutational landscapes. J Pathol. 2013 Jan; 229(1):99-110.
    View in: PubMed
    Score: 0.015
  62. Cancer stem cell markers are enriched in normal tissue adjacent to triple negative breast cancer and inversely correlated with DNA repair deficiency. Breast Cancer Res. 2013; 15(5):R77.
    View in: PubMed
    Score: 0.015
  63. A small-molecule inhibitor targeting the mitotic spindle checkpoint impairs the growth of uterine leiomyosarcoma. Clin Cancer Res. 2012 Jun 15; 18(12):3352-65.
    View in: PubMed
    Score: 0.014
  64. A SUMOylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis. Science. 2012 Jan 20; 335(6066):348-53.
    View in: PubMed
    Score: 0.014
  65. Stem cell antigen-1 (sca-1) regulates mammary tumor development and cell migration. PLoS One. 2011; 6(11):e27841.
    View in: PubMed
    Score: 0.014
  66. Targets of the tumor suppressor miR-200 in regulation of the epithelial-mesenchymal transition in cancer. Cancer Res. 2011 Dec 15; 71(24):7670-82.
    View in: PubMed
    Score: 0.014
  67. Increased midkine expression correlates with desmoid tumour recurrence: a potential biomarker and therapeutic target. J Pathol. 2011 Dec; 225(4):574-82.
    View in: PubMed
    Score: 0.013
  68. FGFR-4 Arg?88 enhances prostate cancer progression via extracellular signal-related kinase and serum response factor signaling. Clin Cancer Res. 2011 Jul 01; 17(13):4355-66.
    View in: PubMed
    Score: 0.013
  69. Estrogen and insulin-like growth factor-I (IGF-I) independently down-regulate critical repressors of breast cancer growth. Breast Cancer Res Treat. 2012 Feb; 132(1):61-73.
    View in: PubMed
    Score: 0.013
  70. Functional microRNA involved in endometriosis. Mol Endocrinol. 2011 May; 25(5):821-32.
    View in: PubMed
    Score: 0.013
  71. Molecular and functional characteristics of ovarian surface epithelial cells transformed by KrasG12D and loss of Pten in a mouse model in vivo. Oncogene. 2011 Aug 11; 30(32):3522-36.
    View in: PubMed
    Score: 0.013
  72. The Notch ligand Jagged2 promotes lung adenocarcinoma metastasis through a miR-200-dependent pathway in mice. J Clin Invest. 2011 Apr; 121(4):1373-85.
    View in: PubMed
    Score: 0.013
  73. High IGF-IR activity in triple-negative breast cancer cell lines and tumorgrafts correlates with sensitivity to anti-IGF-IR therapy. Clin Cancer Res. 2011 Apr 15; 17(8):2314-27.
    View in: PubMed
    Score: 0.013
  74. Suppression of relaxin receptor RXFP1 decreases prostate cancer growth and metastasis. Endocr Relat Cancer. 2010 Dec; 17(4):1021-33.
    View in: PubMed
    Score: 0.013
  75. Fibroblast growth factor receptor signaling dramatically accelerates tumorigenesis and enhances oncoprotein translation in the mouse mammary tumor virus-Wnt-1 mouse model of breast cancer. Cancer Res. 2010 Jun 15; 70(12):4868-79.
    View in: PubMed
    Score: 0.012
  76. CCAAT/enhancer binding protein beta regulates stem cell activity and specifies luminal cell fate in the mammary gland. Stem Cells. 2010 Mar 31; 28(3):535-44.
    View in: PubMed
    Score: 0.012
  77. A link between mir-100 and FRAP1/mTOR in clear cell ovarian cancer. Mol Endocrinol. 2010 Feb; 24(2):447-63.
    View in: PubMed
    Score: 0.012
  78. Large-scale integration of MicroRNA and gene expression data for identification of enriched microRNA-mRNA associations in biological systems. Methods Mol Biol. 2010; 667:297-315.
    View in: PubMed
    Score: 0.012
  79. SAFB1 mediates repression of immune regulators and apoptotic genes in breast cancer cells. J Biol Chem. 2010 Feb 05; 285(6):3608-3616.
    View in: PubMed
    Score: 0.012
  80. Contextual extracellular cues promote tumor cell EMT and metastasis by regulating miR-200 family expression. Genes Dev. 2009 Sep 15; 23(18):2140-51.
    View in: PubMed
    Score: 0.012
  81. Expression signatures of metastatic capacity in a genetic mouse model of lung adenocarcinoma. PLoS One. 2009; 4(4):e5401.
    View in: PubMed
    Score: 0.012
  82. Distinct biological roles for the notch ligands Jagged-1 and Jagged-2. J Biol Chem. 2009 Jun 26; 284(26):17766-74.
    View in: PubMed
    Score: 0.012
  83. Widespread deregulation of microRNA expression in human prostate cancer. Oncogene. 2008 Mar 13; 27(12):1788-93.
    View in: PubMed
    Score: 0.010
  84. Identification of genes modulated in rheumatoid arthritis using complementary DNA microarray analysis of lymphoblastoid B cell lines from disease-discordant monozygotic twins. Arthritis Rheum. 2006 Jul; 54(7):2047-60.
    View in: PubMed
    Score: 0.009
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.