YI-CHENLAIYI-CHEN LAI0.000000000000000.000000000000001076LAI, YI-CHENAssociate Professorprns:coAuthorOfcoauthor ofprns:emailEncryptedemail addressprns:endDateend dateFaculty Rankprns:fullNamefull nameprns:grantAwardedBygrant awarded byprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:physicalNeighborOfphysical neighborprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:principalInvestigatorNameprincipal investigator nameprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:startDatestart dateprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressvivo:address1address line 1vivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provinceAgreementvivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentDivisionGrantvivo:hasResearchArearesearch areasvivo:hasResearcherRoleresearch activitiesvivo:hrJobTitleHR job titleInformation Resourcevivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:personInPositionpositionsPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titleResearcher Rolevivo:researcherRoleOfresearcher role ofRolevivo:roleContributesTocontributes tovivo:sponsorAwardIdsponsor award idrdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPerson25422023Valentine G, Thomas TA, Nguyen T, Lai YCPediatricsChronic granulomatous disease presenting as hemophagocytic lymphohistiocytosis: a case report. Pediatrics. 2014 Dec; 134(6):e1727-30.Pediatrics2014-12-01T00:00:002014Chronic granulomatous disease presenting as hemophagocytic lymphohistiocytosis: a case report.NANBINGLI-VILLARREALNANBING LI-VILLARREAL10361LI-VILLARREAL, NANBINGInstructor6621 FANNINHouston, 77030TXAuthorship 305209126039430Lai YCPediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care SocietiesSeizure Detection in the PICU: Can We "See" Seizures Better in Color? Pediatr Crit Care Med. 2015 Jun; 16(5):486-7.Pediatr Crit Care Med2015-06-01T00:00:002015Seizure Detection in the PICU: Can We "See" Seizures Better in Color?74Professor10Assistant Professor54Instructor14Associate Professor6Adjunct ProfessorPediatrics-Neur NRI CAIN27555091Brewster AL, Marzec K, Hairston A, Ho M, Anderson AE, Lai YCEpilepsiaEarly cardiac electrographic and molecular remodeling in a model of status epilepticus and acquired epilepsy. Epilepsia. 2016 11; 57(11):1907-1915.Epilepsia2016-08-24T00:00:002016Early cardiac electrographic and molecular remodeling in a model of status epilepticus and acquired epilepsy.Authorship 8726966Authorship 8726971Authorship 8726981Authorship 8726992Authorship 8727001Authorship 8727011Authorship 8727021Authorship 8727034Authorship 8727042Authorship 872705217996029Lai Y, Chen Y, Watkins SC, Nathaniel PD, Guo F, Kochanek PM, Jenkins LW, Szab? C, Clark RSJournal of neurochemistryIdentification of poly-ADP-ribosylated mitochondrial proteins after traumatic brain injury. J Neurochem. 2008 Mar; 104(6):1700-11.J Neurochem2007-11-06T00:00:002007Identification of poly-ADP-ribosylated mitochondrial proteins after traumatic brain injury.17786151Lai Y, Hickey RW, Chen Y, Bayir H, Sullivan ML, Chu CT, Kochanek PM, Dixon CE, Jenkins LW, Graham SH, Watkins SC, Clark RSJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and MetabolismAutophagy is increased after traumatic brain injury in mice and is partially inhibited by the antioxidant gamma-glutamylcysteinyl ethyl ester. J Cereb Blood Flow Metab. 2008 Mar; 28(3):540-50.J Cereb Blood Flow Metab2007-09-05T00:00:002007Autophagy is increased after traumatic brain injury in mice and is partially inhibited by the antioxidant gamma-glutamylcysteinyl ethyl ester.16943657Cousar JL, Lai Y, Marco CD, Bayir H, Adelson PD, Janesko-Feldman KL, Kochanek PM, Clark RSDevelopmental neuroscienceHeme oxygenase 1 in cerebrospinal fluid from infants and children after severe traumatic brain injury. Dev Neurosci. 2006; 28(4-5):342-7.Dev Neurosci2006-01-01T00:00:002006Heme oxygenase 1 in cerebrospinal fluid from infants and children after severe traumatic brain injury.16943656Lai Y, Stange C, Wisniewski SR, Adelson PD, Janesko-Feldman KL, Brown DS, Kochanek PM, Clark RSDevelopmental neuroscienceMitochondrial heat shock protein 60 is increased in cerebrospinal fluid following pediatric traumatic brain injury. Dev Neurosci. 2006; 28(4-5):336-41.Dev Neurosci2006-01-01T00:00:002006Mitochondrial heat shock protein 60 is increased in cerebrospinal fluid following pediatric traumatic brain injury.15998287Lai Y, Du L, Dunsmore KE, Jenkins LW, Wong HR, Clark RSJournal of neurochemistrySelectively increasing inducible heat shock protein 70 via TAT-protein transduction protects neurons from nitrosative stress and excitotoxicity. J Neurochem. 2005 Jul; 94(2):360-6.J Neurochem2005-07-01T00:00:002005Selectively increasing inducible heat shock protein 70 via TAT-protein transduction protects neurons from nitrosative stress and excitotoxicity.15115598Lai Y, Kochanek PM, Adelson PD, Janesko K, Ruppel RA, Clark RSJournal of neurotraumaInduction of the stress response after inflicted and non-inflicted traumatic brain injury in infants and children. J Neurotrauma. 2004 Mar; 21(3):229-37.J Neurotrauma2004-03-01T00:00:002004Induction of the stress response after inflicted and non-inflicted traumatic brain injury in infants and children.19114918Bayir H, Adelson PD, Wisniewski SR, Shore P, Lai Y, Brown D, Janesko-Feldman KL, Kagan VE, Kochanek PMCritical care medicineTherapeutic hypothermia preserves antioxidant defenses after severe traumatic brain injury in infants and children. Crit Care Med. 2009 Feb; 37(2):689-95.Crit Care Med2009-02-01T00:00:002009Therapeutic hypothermia preserves antioxidant defenses after severe traumatic brain injury in infants and children.18506195Fink EL, Lai Y, Zhang X, Janesko-Feldman K, Adelson PD, Szab? C, Berger RP, Sarnaik AA, Kochanek PM, Clark RSJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and MetabolismQuantification of poly(ADP-ribose)-modified proteins in cerebrospinal fluid from infants and children after traumatic brain injury. J Cereb Blood Flow Metab. 2008 Sep; 28(9):1523-9.J Cereb Blood Flow Metab2008-05-28T00:00:002008Quantification of poly(ADP-ribose)-modified proteins in cerebrospinal fluid from infants and children after traumatic brain injury.15744250Satchell MA, Lai Y, Kochanek PM, Wisniewski SR, Fink EL, Siedberg NA, Berger RP, DeKosky ST, Adelson PD, Clark RSJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and MetabolismCytochrome c, a biomarker of apoptosis, is increased in cerebrospinal fluid from infants with inflicted brain injury from child abuse. J Cereb Blood Flow Metab. 2005 Jul; 25(7):919-27.J Cereb Blood Flow Metab2005-07-01T00:00:002005Cytochrome c, a biomarker of apoptosis, is increased in cerebrospinal fluid from infants with inflicted brain injury from child abuse.28704930Lai YC, Baker JS, Donti T, Graham BH, Craigen WJ, Anderson AEInternational journal of molecular sciencesMitochondrial Dysfunction Mediated by Poly(ADP-Ribose) Polymerase-1 Activation Contributes to Hippocampal Neuronal Damage Following Status Epilepticus. Int J Mol Sci. 2017 Jul 12; 18(7).Int J Mol Sci2017-07-12T00:00:002017Mitochondrial Dysfunction Mediated by Poly(ADP-Ribose) Polymerase-1 Activation Contributes to Hippocampal Neuronal Damage Following Status Epilepticus.Authorship 876014128695501Lai YC, Aneja RK, Satchell MA, Clark RSBMethods in molecular biology (Clifton, N.J.)Detecting and Quantifying pADPr In Vivo. Methods Mol Biol. 2017; 1608:27-43.Methods Mol Biol2017-01-01T00:00:002017Detecting and Quantifying pADPr In Vivo.Authorship 876645121870258Lai YC, Aneja RK, Satchell MA, Clark RSMethods in molecular biology (Clifton, N.J.)Detecting and quantifying pADPr in vivo. Methods Mol Biol. 2011; 780:117-34.Methods Mol Biol2011-01-01T00:00:002011Detecting and quantifying pADPr in vivo.29430560Ali W, Bubolz BA, Nguyen L, Castro D, Coss-Bu J, Quach MM, Kennedy CE, Anderson AE, Lai YCEpilepsia openEpilepsy is associated with ventricular alterations following convulsive status epilepticus in children. Epilepsia Open. 2017 Dec; 2(4):432-440.Epilepsia Open2017-08-21T00:00:002017Epilepsy is associated with ventricular alterations following convulsive status epilepticus in children.28686803Hussain S, Egbenya DL, Lai YC, Dosa ZJ, S?rensen JB, Anderson AE, Davanger SHippocampusThe calcium sensor synaptotagmin 1 is expressed and regulated in hippocampal postsynaptic spines. Hippocampus. 2017 11; 27(11):1168-1177.Hippocampus2017-07-24T00:00:002017The calcium sensor synaptotagmin 1 is expressed and regulated in hippocampal postsynaptic spines.29643084S?nchez Fern?ndez I, Ga?nza-Lein M, Abend NS, Anderson AE, Arya R, Brenton JN, Carpenter JL, Chapman KE, Clark J, Gaillard WD, Glauser TA, Goldstein JL, Goodkin HP, Helseth AR, Jackson MC, Kapur K, Lai YC, McDonough TL, Mikati MA, Nayak A, Peariso K, Riviello JJ, Tasker RC, Tchapyjnikov D, Topjian AA, Wainwright MS, Wilfong A, Williams K, Loddenkemper T, Pediatric Status Epilepticus Research Group (pSERG)NeurologyFactors associated with treatment delays in pediatric refractory convulsive status epilepticus. Neurology. 2018 05 08; 90(19):e1692-e1701.Neurology2018-04-11T00:00:002018Factors associated with treatment delays in pediatric refractory convulsive status epilepticus.true1ProfessorProfessortrue1ProfessorProfessortrue1Assistant ProfessorAssistant Professortrue1Associate ProfessorAssociate Professortrue1Assistant ProfessorAssistant Professortrue1Assistant ProfessorAssistant Professortrue1ProfessorProfessorD053590Chemicals & Drugs601030.944501Interleukin 1 Receptor Antagonist ProteinAuthorship 8908361Authorship 8908379Authorship 89083818Authorship 890839929881800Lai YC, Li N, Lawrence W, Wang S, Levine A, Burchhardt DM, Pautler RG, Valderr?bano M, Wehrens XH, Anderson AEEpilepsia openMyocardial remodeling and susceptibility to ventricular tachycardia in a model of chronic epilepsy. Epilepsia Open. 2018 Jun; 3(2):213-223.Epilepsia Open2018-03-23T00:00:002018Myocardial remodeling and susceptibility to ventricular tachycardia in a model of chronic epilepsy.29727818Arya R, Peariso K, Ga?nza-Lein M, Harvey J, Bergin A, Brenton JN, Burrows BT, Glauser T, Goodkin HP, Lai YC, Mikati MA, Fern?ndez IS, Tchapyjnikov D, Wilfong AA, Williams K, Loddenkemper T, pediatric Status Epilepticus Research Group (pSERG)Epilepsy researchEfficacy and safety of ketogenic diet for treatment of pediatric convulsive refractory status epilepticus. Epilepsy Res. 2018 08; 144:1-6.Epilepsy Res2018-04-27T00:00:002018Efficacy and safety of ketogenic diet for treatment of pediatric convulsive refractory status epilepticus.D011065Chemicals & Drugs2043240.85046Poly(ADP-ribose) Polymerases30075875Vasquez A, Ga?nza-Lein M, S?nchez Fern?ndez I, Abend NS, Anderson A, Brenton JN, Carpenter JL, Chapman K, Clark J, Gaillard WD, Glauser T, Goldstein J, Goodkin HP, Lai YC, Loddenkemper T, McDonough TL, Mikati MA, Nayak A, Payne E, Riviello J, Tchapyjnikov D, Topjian AA, Wainwright MS, Tasker RC, Pediatric Status Epilepticus Research Group (pSERG)Pediatric neurologyHospital Emergency Treatment of Convulsive Status Epilepticus: Comparison of Pathways From Ten Pediatric Research Centers. Pediatr Neurol. 2018 09; 86:33-41.Pediatr Neurol2018-07-11T00:00:002018Hospital Emergency Treatment of Convulsive Status Epilepticus: Comparison of Pathways From Ten Pediatric Research Centers.D013226Disorders591440.856489Status Epilepticus30064010Egbenya DL, Hussain S, Lai YC, Xia J, Anderson AE, Davanger SMolecular and cellular neurosciencesChanges in synaptic AMPA receptor concentration and composition in chronic temporal lobe epilepsy. Mol Cell Neurosci. 2018 10; 92:93-103.Mol Cell Neurosci2018-07-29T00:00:002018Changes in synaptic AMPA receptor concentration and composition in chronic temporal lobe epilepsy.D004569Procedures2818900.706667Electroencephalography2014-04-30NIHLAI, YI-CHEN2009-05-15PARP-1 activation in seizures and status epilepticusK08NS063117Principal InvestigatorDepartment of MedicineDepartment of NeurologyDepartment of PediatricsPediatrics-RheumatologyMedicine-CardiologyMolecular Physiology & BiophysicsNeurologyPediatrics-Critical CarePediatrics-NeurologyBaylor College of Medicine4.008950.00212304257research areas2.088290.051991827coauthor of57.8945.9540560similar to1150selected publicationsYOCHAIBIRNBAUMYOCHAI BIRNBAUM0.000000000000000.000000000000001504BIRNBAUM, YOCHAIProfessorBRIANRISSMILLERBRIAN RISSMILLER0.000000000000000.000000000000004265RISSMILLER, BRIANAssistant ProfessorANNEANDERSONANNE ANDERSON32.31117320000000-90.076813400000003414ANDERSON, ANNEProfessorPATRICIABASTEROPATRICIA BASTERO0.000000000000000.000000000000004026BASTERO, PATRICIAAssistant ProfessorJAMESRIVIELLO JR.JAMES RIVIELLO JR.29.71073630000000-95.396604500000003888RIVIELLO JR., JAMESProfessorZULFIHANEEFZULFI HANEEF0.000000000000000.000000000000003975HANEEF, ZULFIAssociate ProfessorJENNIFERERKLAUERJENNIFER ERKLAUER0.000000000000000.000000000000004425ERKLAUER, JENNIFERAssistant ProfessorJEFFREYNOEBELSJEFFREY NOEBELS0.000000000000000.000000000000003151NOEBELS, JEFFREYProfessorLAURALOFTISLAURA LOFTIS0.000000000000000.00000000000000680LOFTIS, LAURAAssociate ProfessorEYALMUSCALEYAL MUSCAL0.000000000000000.00000000000000776MUSCAL, EYALProfessorD000069279681800.79264Drug Resistant Epilepsy31166226Sansevere AJ, Arya R, S?nchez Fern?ndez I, Gaillard WD, Tasker RC, Lai YC, Anderson AE, Tchapyjnikov D, Chapman KE, Brenton JN, Carpenter JL, Ga?nza-Lein M, Goldstein JL, Goodkin HP, Jackson MC, Kapur K, Mikati MA, Peariso K, Glauser TA, Topjian AA, Wainwright M, Wilfong AA, Williams KL, Loddenkemper T, Abend NS, Pediatric Status Epilepticus Research Group (pSERG)Journal of clinical neurophysiology : official publication of the American Electroencephalographic SocietyElectroencephalographic Reporting for Refractory Status Epilepticus. J Clin Neurophysiol. 2019 Sep; 36(5):365-370.J Clin Neurophysiol2019-09-01T00:00:002019Electroencephalographic Reporting for Refractory Status Epilepticus.Authorship 9518835Authorship 95188412Authorship 9518853Authorship 951886331323566S?nchez Fern?ndez I, Ga?nza-Lein M, Abend NS, Amengual-Gual M, Anderson A, Arya R, Brenton JN, Carpenter JL, Chapman KE, Clark J, Farias-Moeller R, Davis Gaillard W, Glauser TA, Goldstein J, Goodkin HP, Guerriero RM, Hecox K, Jackson M, Kapur K, Kelley SA, Kossoff EHW, Lai YC, McDonough TL, Mikati MA, Morgan LA, Novotny EJ, Ostendorf AP, Payne ET, Peariso K, Piantino J, Riviello JJ, Sannagowdara K, Stafstrom CE, Tasker RC, Tchapyjnikov D, Topjian AA, Vasquez A, Wainwright MS, Wilfong A, Williams K, Loddenkemper T, Pediatric Status Epilepticus Research GroupSeizureThe onset of pediatric refractory status epilepticus is not distributed uniformly during the day. Seizure. 2019 Aug; 70:90-96.Seizure2019-06-18T00:00:002019The onset of pediatric refractory status epilepticus is not distributed uniformly during the day.COREYCHARTANNaMx83HGLqv3RYKj5X/XCOREY CHARTAN0.000000000000000.000000000000006131CHARTAN, COREYAssociate ProfessorMATTHEWPESEKMATTHEW PESEK0.000000000000000.000000000000006151PESEK, MATTHEWAssociate ProfessorAuthorship 979778832132552Levine AT, Born HA, Landstrom AP, Larson S, Lee WL, Dao AT, Wehrens XH, Lai YC, Anderson AEScientific reportsCardiac dysregulation following intrahippocampal kainate-induced status epilepticus. Sci Rep. 2020 03 04; 10(1):4043.Sci Rep2020-03-04T00:00:002020Cardiac dysregulation following intrahippocampal kainate-induced status epilepticus.true1Associate ProfessorAssociate ProfessorAuthorship 99538119Authorship 9982811932611646S?nchez Fern?ndez I, Abend NS, Amengual-Gual M, Anderson A, Arya R, Barcia Aguilar C, Brenton JN, Carpenter JL, Chapman KE, Clark J, Farias-Moeller R, Gaillard WD, Ga?nza-Lein M, Glauser T, Goldstein J, Goodkin HP, Guerriero RM, Lai YC, McDonough T, Mikati MA, Morgan LA, Novotny E, Payne E, Peariso K, Piantino J, Ostendorf A, Sands TT, Sannagowdara K, Tasker RC, Tchapyjnikov D, Topjian AA, Vasquez A, Wainwright MS, Wilfong A, Williams K, Loddenkemper T, pSERGNeurologyAssociation of guideline publication and delays to treatment in pediatric status epilepticus. Neurology. 2020 09 01; 95(9):e1222-e1235.Neurology2020-07-01T00:00:002020Association of guideline publication and delays to treatment in pediatric status epilepticus.true1Associate ProfessorAssociate ProfessorAuthorship 10040341932913024Vasquez A, Ga?nza-Lein M, Abend NS, Amengual-Gual M, Anderson A, Arya R, Brenton JN, Carpenter JL, Chapman K, Clark J, Farias-Moeller R, Gaillard WD, Glauser T, Goldstein JL, Goodkin HP, Guerriero RM, Kapur K, Lai YC, McDonough TL, Mikati MA, Morgan LA, Novotny EJ, Ostendorf AP, Payne ET, Peariso K, Piantino J, Riviello JJ, Sannagowdara K, Tasker RC, Tchapyjnikov D, Topjian A, Wainwright MS, Wilfong A, Williams K, Loddenkemper T, Pediatric Status Epilepticus Research Group (pSERG)NeurologyFirst-line medication dosing in pediatric refractory status epilepticus. Neurology. 2020 11 10; 95(19):e2683-e2696.Neurology2020-09-10T00:00:002020First-line medication dosing in pediatric refractory status epilepticus.Authorship 1010027133506622Lai YC, Muscal E, Wells E, Shukla N, Eschbach K, Hyeong Lee K, Kaliakatsos M, Desai N, Wickstr?m R, Viri M, Freri E, Granata T, Nangia S, Dilena R, Brunklaus A, Wainwright MS, Gorman MP, Stredny CM, Asiri A, Hundallah K, Doja A, Payne E, Wirrell E, Koh S, Carpenter JL, Riviello JAnnals of clinical and translational neurologyAnakinra usage in febrile infection related epilepsy syndrome: an international cohort. Ann Clin Transl Neurol. 2020 12; 7(12):2467-2474.Ann Clin Transl Neurol2020-12-04T00:00:002020Anakinra usage in febrile infection related epilepsy syndrome: an international cohort.33681649Koh S, Wirrell E, Vezzani A, Nabbout R, Muscal E, Kaliakatsos M, Wickstr?m R, Riviello JJ, Brunklaus A, Payne E, Valentin A, Wells E, Carpenter JL, Lee K, Lai YC, Eschbach K, Press CA, Gorman M, Stredny CM, Roche W, Mangum TEpilepsia openProposal to optimize evaluation and treatment of Febrile infection-related epilepsy syndrome (FIRES): A Report from FIRES workshop. Epilepsia Open. 2021 03; 6(1):62-72.Epilepsia Open2021-01-13T00:00:002021Proposal to optimize evaluation and treatment of Febrile infection-related epilepsy syndrome (FIRES): A Report from FIRES workshop.true1Associate ProfessorAssociate Professor34091885Sculier C, Barcia Aguilar C, Gaspard N, Ga?nza-Lein M, S?nchez Fern?ndez I, Amengual-Gual M, Anderson A, Arya R, Burrows BT, Brenton JN, Carpenter JL, Chapman KE, Clark J, Gaillard WD, Glauser TA, Goldstein JL, Goodkin HP, Gorman M, Lai YC, McDonough TL, Mikati MA, Nayak A, Peariso K, Riviello J, Rusie A, Sperberg K, Stredny CM, Tasker RC, Tchapyjnikov D, Vasquez A, Wainwright MS, Wilfong AA, Williams K, Loddenkemper T, pSERGEpilepsiaClinical presentation of new onset refractory status epilepticus in children (the pSERG cohort). Epilepsia. 2021 07; 62(7):1629-1642.Epilepsia2021-06-06T00:00:002021Clinical presentation of new onset refractory status epilepticus in children (the pSERG cohort).Authorship 10210741634120133Vasquez A, Farias-Moeller R, S?nchez-Fern?ndez I, Abend NS, Amengual-Gual M, Anderson A, Arya R, Brenton JN, Carpenter JL, Chapman K, Clark J, Gaillard WD, Glauser T, Goldstein JL, Goodkin HP, Guerriero RM, Lai YC, McDonough TL, Mikati MA, Morgan LA, Novotny EJ, Ostendorf AP, Payne ET, Peariso K, Piantino J, Riviello JJ, Sands TT, Sannagowdara K, Tasker RC, Tchapyjnikov D, Topjian A, Wainwright MS, Wilfong A, Williams K, Loddenkemper T, Pediatric Status Epilepticus Research Group (pSERG)Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care SocietiesSuper-Refractory Status Epilepticus in Children: A Retrospective Cohort Study. Pediatr Crit Care Med. 2021 12 01; 22(12):e613-e625.Pediatr Crit Care Med2021-12-01T00:00:002021Super-Refractory Status Epilepticus in Children: A Retrospective Cohort Study.CHSA Pedi-Neurology2022-12-31NIHLAI, YI-CHEN2021-07-01Assessing determinants of electrocardiographic alterations and identifying exacerbating factors in pediatric epilepsyR21NS119929Principal InvestigatorAuthorship 10243832Authorship 1024624534215385Martinez LA, Lai YC, Holder JL, Anderson AENeurologic clinicsGenetics in Epilepsy. Neurol Clin. 2021 08; 39(3):743-777.Neurol Clin2021-08-01T00:00:002021Genetics in Epilepsy.34235879Chan SW, Dervan LA, Watson RS, Anderson AE, Lai YCEpilepsia openEpilepsy duration is an independent factor for electrocardiographic changes in pediatric epilepsy. Epilepsia Open. 2021 09; 6(3):588-596.Epilepsia Open2021-07-19T00:00:002021Epilepsy duration is an independent factor for electrocardiographic changes in pediatric epilepsy.34251039Ga?nza-Lein M, Barcia Aguilar C, Piantino J, Chapman KE, S?nchez Fern?ndez I, Amengual-Gual M, Anderson A, Appavu B, Arya R, Brenton JN, Carpenter JL, Clark J, Farias-Moeller R, Gaillard WD, Glauser TA, Goldstein JL, Goodkin HP, Huh L, Kahoud R, Kapur K, Lai YC, McDonough TL, Mikati MA, Morgan LA, Nayak A, Novotny E, Ostendorf AP, Payne ET, Peariso K, Reece L, Riviello J, Sannagowdara K, Sands TT, Sheehan T, Tasker RC, Tchapyjnikov D, Vasquez A, Wainwright MS, Wilfong A, Williams K, Zhang B, Loddenkemper T, Pediatric Status Epilepticus Research GroupEpilepsiaFactors associated with long-term outcomes in pediatric refractory status epilepticus. Epilepsia. 2021 09; 62(9):2190-2204.Epilepsia2021-07-12T00:00:002021Factors associated with long-term outcomes in pediatric refractory status epilepticus.Authorship 104785822Authorship 104785919Authorship 104786014Authorship 10478614Authorship 10478622Authorship 10478637Authorship 10478645Authorship 10478652Authorship 10478669Authorship 1047867Authorship 10478681714987343Fink EL, Alexander H, Marco CD, Dixon CE, Kochanek PM, Jenkins LW, Lai Y, Donovan HA, Hickey RW, Clark RSPediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care SocietiesExperimental model of pediatric asphyxial cardiopulmonary arrest in rats. Pediatr Crit Care Med. 2004 Mar; 5(2):139-44.Pediatr Crit Care Med2004-03-01T00:00:002004Experimental model of pediatric asphyxial cardiopulmonary arrest in rats.16943664Kochanek AR, Kline AE, Gao WM, Chadha M, Lai Y, Clark RS, Dixon CE, Jenkins LWDevelopmental neuroscienceGel-based hippocampal proteomic analysis 2 weeks following traumatic brain injury to immature rats using controlled cortical impact. Dev Neurosci. 2006; 28(4-5):410-9.Dev Neurosci2006-01-01T00:00:002006Gel-based hippocampal proteomic analysis 2 weeks following traumatic brain injury to immature rats using controlled cortical impact.31611646Ansorge R, Romano S, Sayavedra L, Porras M?G, Kupczok A, Tegetmeyer HE, Dubilier N, Petersen JNature microbiologyFunctional diversity enables multiple symbiont strains to coexist in deep-sea mussels. Nat Microbiol. 2019 12; 4(12):2487-2497.Nat Microbiol2019-10-14T00:00:002019Functional diversity enables multiple symbiont strains to coexist in deep-sea mussels.34418087Sheehan T, Amengual-Gual M, Vasquez A, Abend NS, Anderson A, Appavu B, Arya R, Barcia Aguilar C, Brenton JN, Carpenter JL, Chapman KE, Clark J, Farias-Moeller R, Gaillard WD, Ga?nza-Lein M, Glauser TA, Goldstein JL, Goodkin HP, Guerriero RM, Huh L, Jackson M, Kapur K, Kahoud R, Lai YC, McDonough TL, Mikati MA, Morgan LA, Novotny EJ, Ostendorf AP, Payne ET, Peariso K, Piantino J, Reece L, Riviello JJ, Sands TT, Sannagowdara K, Shellhaas R, Smith G, Tasker RC, Tchapyjnikov D, Topjian AA, Wainwright MS, Wilfong A, Williams K, Zhang B, Loddenkemper T, Pediatric Status Epilepticus Research GroupEpilepsiaBenzodiazepine administration patterns before escalation to second-line medications in pediatric refractory convulsive status epilepticus. Epilepsia. 2021 11; 62(11):2766-2777.Epilepsia2021-08-21T00:00:002021Benzodiazepine administration patterns before escalation to second-line medications in pediatric refractory convulsive status epilepticus.12558971Seidberg NA, Clark RS, Zhang X, Lai Y, Chen M, Graham SH, Kochanek PM, Watkins SC, Marion DWJournal of neurochemistryAlterations in inducible 72-kDa heat shock protein and the chaperone cofactor BAG-1 in human brain after head injury. J Neurochem. 2003 Feb; 84(3):514-21.J Neurochem2003-02-01T00:00:002003Alterations in inducible 72-kDa heat shock protein and the chaperone cofactor BAG-1 in human brain after head injury.17263671Shore PM, Berger RP, Varma S, Janesko KL, Wisniewski SR, Clark RS, Adelson PD, Thomas NJ, Lai YC, Bayir H, Kochanek PMJournal of neurotraumaCerebrospinal fluid biomarkers versus glasgow coma scale and glasgow outcome scale in pediatric traumatic brain injury: the role of young age and inflicted injury. J Neurotrauma. 2007 Jan; 24(1):75-86.J Neurotrauma2007-01-01T00:00:002007Cerebrospinal fluid biomarkers versus glasgow coma scale and glasgow outcome scale in pediatric traumatic brain injury: the role of young age and inflicted injury.17115134Di Filippo S, Lai Y, Manrique A, Pigula F, Mu?oz RIntensive care medicineIntensive care course after stage 1 Norwood procedure: are there early predictors of failure? Intensive Care Med. 2007 Jan; 33(1):111-9.Intensive Care Med2006-11-18T00:00:002006Intensive care course after stage 1 Norwood procedure: are there early predictors of failure?15234982Du L, Bayir H, Lai Y, Zhang X, Kochanek PM, Watkins SC, Graham SH, Clark RSThe Journal of biological chemistryInnate gender-based proclivity in response to cytotoxicity and programmed cell death pathway. J Biol Chem. 2004 Sep 10; 279(37):38563-70.J Biol Chem2004-07-01T00:00:002004Innate gender-based proclivity in response to cytotoxicity and programmed cell death pathway.true1ProfessorProfessortrue1InstructorInstructorDepartment of Integrative Physiology36029730Erklauer JC, Thammasitboon S, Shekerdemian LS, Riviello JJ, Lai YCPediatric neurologyCreating a Robust Community of Practice as a Foundation for the Successful Development of a Pediatric Neurocritical Care Program. Pediatr Neurol. 2022 11; 136:1-7.Pediatr Neurol2022-08-07T00:00:002022Creating a Robust Community of Practice as a Foundation for the Successful Development of a Pediatric Neurocritical Care Program.Authorship 10558511Authorship 10598115Authorship 1057815636200780Herman I, Nguyen T, Chan SW, Erklauer J, Riviello JJ, Lai YCPediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care SocietiesImplementation of a Pediatric Neurocritical Care Program for Children With Status Epilepticus: Adherence to Continuous Electroencephalogram Monitoring. Pediatr Crit Care Med. 2022 12 01; 23(12):1037-1046.Pediatr Crit Care Med2022-10-05T00:00:002022Implementation of a Pediatric Neurocritical Care Program for Children With Status Epilepticus: Adherence to Continuous Electroencephalogram Monitoring.36645080Lai YC, Abou-El-Kheir G, Nguyen T, Hanerhoff M, Riviello JJ, Muscal EAnnals of clinical and translational neurologySystemic inflammatory markers and EEG features of children with FIRES receiving anakinra. Ann Clin Transl Neurol. 2023 03; 10(3):440-446.Ann Clin Transl Neurol2023-01-16T00:00:002023Systemic inflammatory markers and EEG features of children with FIRES receiving anakinra.36325804Tlais D, Fetzko S, Gulati N, Tran HBD, Risen S, Lai YCPediatricsA Toddler With New Seizures, Progressive White Matter Lesions, and Multifocal Microhemorrhages. Pediatrics. 2022 12 01; 150(6).Pediatrics2022-12-01T00:00:002022A Toddler With New Seizures, Progressive White Matter Lesions, and Multifocal Microhemorrhages.Authorship 10760132537295955Peariso K, Arya R, Glauser T, Abend NS, Barcia Aguilar C, Amengual-Gual M, Anderson A, Appavu BL, Brenton JN, Carpenter J, Chapman KE, Clark J, Gaillard WD, Ga?nza-Lein M, Goldstein J, Goodkin H, Grinspan Z, Guerriero RM, Horn PS, Huh L, Kahoud R, Kelley SA, Kossoff EH, Kapur K, Lai YC, Marquis BO, McDonough T, Mikati MA, Morgan L, Novotny E, Ostendorf AP, Payne ET, Piantino J, Riviello J, Sands T, Stafstrom CE, Tasker RC, Tchapyjnikov D, Vasquez A, Wainwright MS, Wilfong A, Williams K, Loddenkemper T, for Pediatric Status Epilepticus Research Group (pSERG)NeurologyEarly Clinical Variables Associated With Refractory Convulsive Status Epilepticus in Children. Neurology. 2023 08 01; 101(5):e546-e557.Neurology2023-06-09T00:00:002023Early Clinical Variables Associated With Refractory Convulsive Status Epilepticus in Children.37544084Kannan V, Sandweiss AJ, Erickson TA, Yarimi JM, Ankar A, Hardwick VA, Shukla NM, Lotze TE, Risen SR, Riviello JJ, Lai YC, Moeller KK, Fisher KPediatric neurologyFulminant Anti-Myelin Oligodendrocyte Glycoprotein-Associated Cerebral Cortical Encephalitis: Case Series of a Severe Pediatric Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease Phenotype. Pediatr Neurol. 2023 10; 147:36-43.Pediatr Neurol2023-07-11T00:00:002023Fulminant Anti-Myelin Oligodendrocyte Glycoprotein-Associated Cerebral Cortical Encephalitis: Case Series of a Severe Pediatric Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease Phenotype.Authorship 10765476Authorship 1076548336535366Egbenya DL, Hussain S, Lai YC, Anderson AE, Davanger SNeuroscience researchSynapse-specific changes in Arc and BDNF in rat hippocampus following chronic temporal lobe epilepsy. Neurosci Res. 2023 Jun; 191:1-12.Neurosci Res2022-12-16T00:00:002022Synapse-specific changes in Arc and BDNF in rat hippocampus following chronic temporal lobe epilepsy.Authorship 107865411true1Adjunct ProfessorAdjunct ProfessorAuthorship 1081644237864125Erklauer JC, Lai YCNeurocritical careThe State of the Field of Pediatric Multimodality Neuromonitoring. Neurocrit Care. 2023 Oct 20.Neurocrit Care2023-10-20T00:00:002023The State of the Field of Pediatric Multimodality Neuromonitoring.true1ProfessorProfessortrue1Associate ProfessorAssociate ProfessorYU-TZENGYU-TZE NG7903NG, YU-TZEAdjunct ProfessorAuthorship 950081Authorship 1548494