D051928Chemicals & DrugsD12.776.395.550.014D12.776.543.550.14724260.976237CD47 AntigenFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:meshTreeNumberMeSH tree numberprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierDepartmentDivisionvivo:hrJobTitleHR job titleInformation ResourcePositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlevivo:researchAreaOfresearch area ofvivo:subjectAreaForsubject area forrdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonMELANIESAMUELMELANIE SAMUEL8206SAMUEL, MELANIEAssociate ProfessorGI Medical OncologyInvestigational Cancer TherapeuticsMD AndersonJAFFER AAJANIJAFFER A AJANI8473AJANI, JAFFER AProfessorDAVID SANGHYUNHONGDAVID SANGHYUN HONG9016HONG, DAVID SANGHYUNAssociate ProfessorMICHAELCURRANMICHAEL CURRAN9863CURRAN, MICHAELAssistant Professor74Professor10Assistant Professor14Associate Professor29891680Wu J, Wu H, An J, Ballantyne CM, Cyster JGProceedings of the National Academy of Sciences of the United States of AmericaCritical role of integrin CD11c in splenic dendritic cell capture of missing-self CD47 cells to induce adaptive immunity. Proc Natl Acad Sci U S A. 2018 06 26; 115(26):6786-6791.Proc Natl Acad Sci U S A2018-06-11T00:00:002018Critical role of integrin CD11c in splenic dendritic cell capture of missing-self CD47 cells to induce adaptive immunity.30291336Yan B, Chen Q, Shimada K, Tang M, Li H, Gurumurthy A, Khoury JD, Xu B, Huang S, Qiu YLeukemiaHistone deacetylase inhibitor targets CD123/CD47-positive cells and reverse chemoresistance phenotype in acute myeloid leukemia. Leukemia. 2019 04; 33(4):931-944.Leukemia2018-10-05T00:00:002018Histone deacetylase inhibitor targets CD123/CD47-positive cells and reverse chemoresistance phenotype in acute myeloid leukemia.0.9767440.0276824research area of0.9094760.11341513subject area forImmunologyDepartment of NeuroscienceNeuroscienceBaylor College of Medicine31547758Gholamin S, Youssef OA, Rafat M, Esparza R, Kahn S, Shahin M, Giaccia AJ, Graves EE, Weissman I, Mitra S, Cheshier SHInnate immunityIrradiation or temozolomide chemotherapy enhances anti-CD47 treatment of glioblastoma. Innate Immun. 2020 02; 26(2):130-137.Innate Immun2019-09-23T00:00:002019Irradiation or temozolomide chemotherapy enhances anti-CD47 treatment of glioblastoma.71Postdoc Fellows and AssociatesPostDoctrue1Postdoc Fellows and AssociatesPostdoc Fellows and AssociatesRobertMackinRobert Daniel Mackin16168Mackin, RobertPostdoc Fellows and Associatestrue1Associate ProfessorAssociate Professor35687697Hsieh RC, Krishnan S, Wu RC, Boda AR, Liu A, Winkler M, Hsu WH, Lin SH, Hung MC, Chan LC, Bhanu KR, Srinivasamani A, De Azevedo RA, Chou YC, DePinho RA, Gubin M, Vilar E, Chen CH, Slay R, Jayaprakash P, Hegde SM, Hartley G, Lea ST, Prasad R, Morrow B, Couillault CA, Steiner M, Wang CC, Venkatesulu BP, Taniguchi C, Kim YSB, Chen J, Rudqvist NP, Curran MAScience immunologyATR-mediated CD47 and PD-L1 up-regulation restricts radiotherapy-induced immune priming and abscopal responses in colorectal cancer. Sci Immunol. 2022 06 10; 7(72):eabl9330.Sci Immunol2022-06-10T00:00:002022ATR-mediated CD47 and PD-L1 up-regulation restricts radiotherapy-induced immune priming and abscopal responses in colorectal cancer.36379210Jiang D, Burger CA, Akhanov V, Liang JH, Mackin RD, Albrecht NE, Andrade P, Schafer DP, Samuel MAImmunityNeuronal signal-regulatory protein alpha drives microglial phagocytosis by limiting microglial interaction with CD47 in the retina. Immunity. 2022 12 13; 55(12):2318-2335.e7.Immunity2022-11-14T00:00:002022Neuronal signal-regulatory protein alpha drives microglial phagocytosis by limiting microglial interaction with CD47 in the retina.true1ProfessorProfessortrue1Associate ProfessorAssociate Professortrue1Assistant ProfessorAssistant Professor