Connection

FRITZ SEDLAZECK to Genome, Human

This is a "connection" page, showing publications FRITZ SEDLAZECK has written about Genome, Human.
Connection Strength

8.092
  1. Closing the gaps, and improving somatic structural variant analysis and benchmarking using CHM13-T2T. Genome Res. 2025 Apr 14; 35(4):621-631.
    View in: PubMed
    Score: 0.566
  2. A Hitchhiker's Guide to long-read genomic analysis. Genome Res. 2025 Apr 14; 35(4):545-558.
    View in: PubMed
    Score: 0.566
  3. Comprehensive genome analysis and variant detection at scale using DRAGEN. Nat Biotechnol. 2025 Jul; 43(7):1177-1191.
    View in: PubMed
    Score: 0.548
  4. Impact and characterization of serial structural variations across humans and great apes. Nat Commun. 2024 09 13; 15(1):8007.
    View in: PubMed
    Score: 0.544
  5. MethPhaser: methylation-based long-read haplotype phasing of human genomes. Nat Commun. 2024 Jun 22; 15(1):5327.
    View in: PubMed
    Score: 0.535
  6. Analysis and benchmarking of small and large genomic variants across tandem repeats. Nat Biotechnol. 2025 Mar; 43(3):431-442.
    View in: PubMed
    Score: 0.529
  7. FixItFelix: improving genomic analysis by fixing reference errors. Genome Biol. 2023 02 21; 24(1):31.
    View in: PubMed
    Score: 0.488
  8. Towards population-scale long-read sequencing. Nat Rev Genet. 2021 09; 22(9):572-587.
    View in: PubMed
    Score: 0.433
  9. Optimized sample selection for cost-efficient long-read population sequencing. Genome Res. 2021 05; 31(5):910-918.
    View in: PubMed
    Score: 0.428
  10. Development and extensive sequencing of a broadly-consented Genome in a Bottle matched tumor-normal pair. Sci Data. 2025 Jul 16; 12(1):1195.
    View in: PubMed
    Score: 0.144
  11. Long-read sequencing of 945 Han individuals identifies structural variants associated with phenotypic diversity and disease susceptibility. Nat Commun. 2025 Feb 10; 16(1):1494.
    View in: PubMed
    Score: 0.140
  12. High-coverage nanopore sequencing of samples from the 1000 Genomes Project to build a comprehensive catalog of human genetic variation. Genome Res. 2024 Nov 20; 34(11):2061-2073.
    View in: PubMed
    Score: 0.138
  13. Leveraging the T2T assembly to resolve rare and pathogenic inversions in reference genome gaps. Genome Res. 2024 Nov 20; 34(11):1785-1797.
    View in: PubMed
    Score: 0.138
  14. The GIAB genomic stratifications resource for human reference genomes. Nat Commun. 2024 10 19; 15(1):9029.
    View in: PubMed
    Score: 0.137
  15. Single-cell somatic copy number variants in brain using different amplification methods and reference genomes. Commun Biol. 2024 Oct 09; 7(1):1288.
    View in: PubMed
    Score: 0.137
  16. Unveiling novel genetic variants in 370 challenging medically relevant genes using the long read sequencing data of 41 samples from 19 global populations. Mol Genet Genomics. 2024 Jul 07; 299(1):65.
    View in: PubMed
    Score: 0.134
  17. Utility of long-read sequencing for All of Us. Nat Commun. 2024 Jan 29; 15(1):837.
    View in: PubMed
    Score: 0.130
  18. Scalable Nanopore sequencing of human genomes provides a comprehensive view of haplotype-resolved variation and methylation. Nat Methods. 2023 10; 20(10):1483-1492.
    View in: PubMed
    Score: 0.127
  19. Multiscale analysis of pangenomes enables improved representation of genomic diversity for repetitive and clinically relevant genes. Nat Methods. 2023 08; 20(8):1213-1221.
    View in: PubMed
    Score: 0.125
  20. Variant calling and benchmarking in an era of complete human genome sequences. Nat Rev Genet. 2023 07; 24(7):464-483.
    View in: PubMed
    Score: 0.123
  21. SVhound: detection of regions that harbor yet undetected structural variation. BMC Bioinformatics. 2023 Jan 20; 24(1):23.
    View in: PubMed
    Score: 0.121
  22. Truvari: refined structural variant comparison preserves allelic diversity. Genome Biol. 2022 12 27; 23(1):271.
    View in: PubMed
    Score: 0.121
  23. Multiple genome alignment in the telomere-to-telomere assembly era. Genome Biol. 2022 08 29; 23(1):182.
    View in: PubMed
    Score: 0.118
  24. A complete reference genome improves analysis of human genetic variation. Science. 2022 04; 376(6588):eabl3533.
    View in: PubMed
    Score: 0.115
  25. The complete sequence of a human genome. Science. 2022 04; 376(6588):44-53.
    View in: PubMed
    Score: 0.115
  26. Curated variation benchmarks for challenging medically relevant autosomal genes. Nat Biotechnol. 2022 05; 40(5):672-680.
    View in: PubMed
    Score: 0.114
  27. Assessing reproducibility of inherited variants detected with short-read whole genome sequencing. Genome Biol. 2022 01 03; 23(1):2.
    View in: PubMed
    Score: 0.113
  28. PRINCESS: comprehensive detection of haplotype resolved SNVs, SVs, and methylation. Genome Biol. 2021 09 14; 22(1):268.
    View in: PubMed
    Score: 0.110
  29. Parliament2: Accurate structural variant calling at scale. Gigascience. 2020 12 21; 9(12).
    View in: PubMed
    Score: 0.105
  30. Chromosome-scale, haplotype-resolved assembly of human genomes. Nat Biotechnol. 2021 03; 39(3):309-312.
    View in: PubMed
    Score: 0.105
  31. Nanopore sequencing and the Shasta toolkit enable efficient de novo assembly of eleven human genomes. Nat Biotechnol. 2020 09; 38(9):1044-1053.
    View in: PubMed
    Score: 0.100
  32. Accurate circular consensus long-read sequencing improves variant detection and assembly of a human genome. Nat Biotechnol. 2019 10; 37(10):1155-1162.
    View in: PubMed
    Score: 0.096
  33. Atlas-CNV: a validated approach to call single-exon CNVs in the eMERGESeq gene panel. Genet Med. 2019 09; 21(9):2135-2144.
    View in: PubMed
    Score: 0.093
  34. A multi-task convolutional deep neural network for variant calling in single molecule sequencing. Nat Commun. 2019 03 01; 10(1):998.
    View in: PubMed
    Score: 0.093
  35. Accurate detection of complex structural variations using single-molecule sequencing. Nat Methods. 2018 06; 15(6):461-468.
    View in: PubMed
    Score: 0.087
  36. Unraveling the hidden complexity of cancer through long-read sequencing. Genome Res. 2025 Apr 14; 35(4):599-620.
    View in: PubMed
    Score: 0.035
  37. Small variant benchmark from a complete assembly of X and Y chromosomes. Nat Commun. 2025 Jan 08; 16(1):497.
    View in: PubMed
    Score: 0.035
  38. StratoMod: predicting sequencing and variant calling errors with interpretable machine learning. Commun Biol. 2024 Oct 13; 7(1):1316.
    View in: PubMed
    Score: 0.034
  39. Inverted triplications formed by iterative template switches generate structural variant diversity at genomic disorder loci. Cell Genom. 2024 Jul 10; 4(7):100590.
    View in: PubMed
    Score: 0.033
  40. Characterization and visualization of tandem repeats at genome scale. Nat Biotechnol. 2024 Oct; 42(10):1606-1614.
    View in: PubMed
    Score: 0.032
  41. Genome-Wide Analysis of Structural Variants in Parkinson Disease. Ann Neurol. 2023 05; 93(5):1012-1022.
    View in: PubMed
    Score: 0.030
  42. Vulcan: Improved long-read mapping and structural variant calling via dual-mode alignment. Gigascience. 2021 09 24; 10(9).
    View in: PubMed
    Score: 0.028
  43. Performance assessment of DNA sequencing platforms in the ABRF Next-Generation Sequencing Study. Nat Biotechnol. 2021 09; 39(9):1129-1140.
    View in: PubMed
    Score: 0.028
  44. Simultaneous profiling of chromatin accessibility and methylation on human cell lines with nanopore sequencing. Nat Methods. 2020 12; 17(12):1191-1199.
    View in: PubMed
    Score: 0.026
  45. A diploid assembly-based benchmark for variants in the major histocompatibility complex. Nat Commun. 2020 09 22; 11(1):4794.
    View in: PubMed
    Score: 0.026
  46. Paragraph: a graph-based structural variant genotyper for short-read sequence data. Genome Biol. 2019 12 19; 20(1):291.
    View in: PubMed
    Score: 0.024
  47. Megabase Length Hypermutation Accompanies Human Structural Variation at 17p11.2. Cell. 2019 03 07; 176(6):1310-1324.e10.
    View in: PubMed
    Score: 0.023
  48. Complex rearrangements and oncogene amplifications revealed by long-read DNA and RNA sequencing of a breast cancer cell line. Genome Res. 2018 08; 28(8):1126-1135.
    View in: PubMed
    Score: 0.022
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.