Connection

FRITZ SEDLAZECK to Humans

This is a "connection" page, showing publications FRITZ SEDLAZECK has written about Humans.
Connection Strength

0.794
  1. Identification of allele-specific KIV-2 repeats and impact on Lp(a) measurements for cardiovascular disease risk. BMC Med Genomics. 2024 10 24; 17(1):255.
    View in: PubMed
    Score: 0.026
  2. Impact and characterization of serial structural variations across humans and great apes. Nat Commun. 2024 Sep 13; 15(1):8007.
    View in: PubMed
    Score: 0.026
  3. MethPhaser: methylation-based long-read haplotype phasing of human genomes. Nat Commun. 2024 Jun 22; 15(1):5327.
    View in: PubMed
    Score: 0.026
  4. Unveiling microbial diversity: harnessing long-read sequencing technology. Nat Methods. 2024 Jun; 21(6):954-966.
    View in: PubMed
    Score: 0.025
  5. Utility of long-read sequencing for All of Us. Nat Commun. 2024 Jan 29; 15(1):837.
    View in: PubMed
    Score: 0.025
  6. Detection of mosaic and population-level structural variants with Sniffles2. Nat Biotechnol. 2024 Oct; 42(10):1571-1580.
    View in: PubMed
    Score: 0.025
  7. FixItFelix: improving genomic analysis by fixing reference errors. Genome Biol. 2023 02 21; 24(1):31.
    View in: PubMed
    Score: 0.023
  8. SVhound: detection of regions that harbor yet undetected structural variation. BMC Bioinformatics. 2023 Jan 20; 24(1):23.
    View in: PubMed
    Score: 0.023
  9. Truvari: refined structural variant comparison preserves allelic diversity. Genome Biol. 2022 12 27; 23(1):271.
    View in: PubMed
    Score: 0.023
  10. Fully resolved assembly of Cryptosporidium parvum. Gigascience. 2022 02 15; 11.
    View in: PubMed
    Score: 0.022
  11. PRINCESS: comprehensive detection of haplotype resolved SNVs, SVs, and methylation. Genome Biol. 2021 09 14; 22(1):268.
    View in: PubMed
    Score: 0.021
  12. Towards population-scale long-read sequencing. Nat Rev Genet. 2021 09; 22(9):572-587.
    View in: PubMed
    Score: 0.021
  13. Optimized sample selection for cost-efficient long-read population sequencing. Genome Res. 2021 05; 31(5):910-918.
    View in: PubMed
    Score: 0.020
  14. Parliament2: Accurate structural variant calling at scale. Gigascience. 2020 12 21; 9(12).
    View in: PubMed
    Score: 0.020
  15. PhaseME: Automatic rapid assessment of phasing quality and phasing improvement. Gigascience. 2020 07 01; 9(7).
    View in: PubMed
    Score: 0.019
  16. Evaluation of computational genotyping of structural variation for clinical diagnoses. Gigascience. 2019 09 01; 8(9).
    View in: PubMed
    Score: 0.018
  17. Piercing the dark matter: bioinformatics of long-range sequencing and mapping. Nat Rev Genet. 2018 06; 19(6):329-346.
    View in: PubMed
    Score: 0.017
  18. Accurate detection of complex structural variations using single-molecule sequencing. Nat Methods. 2018 06; 15(6):461-468.
    View in: PubMed
    Score: 0.017
  19. Updating benchtop sequencing performance comparison. Nat Biotechnol. 2013 Apr; 31(4):294-6.
    View in: PubMed
    Score: 0.012
  20. Benefit-of-doubt (BOD) scoring: a sequencing-based method for SNP candidate assessment from high to medium read number data sets. Genomics. 2013 Mar; 101(3):204-9.
    View in: PubMed
    Score: 0.011
  21. Long-read sequencing of 945 Han individuals identifies structural variants associated with phenotypic diversity and disease susceptibility. Nat Commun. 2025 Feb 10; 16(1):1494.
    View in: PubMed
    Score: 0.007
  22. Small variant benchmark from a complete assembly of X and Y chromosomes. Nat Commun. 2025 Jan 08; 16(1):497.
    View in: PubMed
    Score: 0.007
  23. Structural variant allelic heterogeneity in MECP2 duplication syndrome provides insight into clinical severity and variability of disease expression. Genome Med. 2024 Dec 18; 16(1):146.
    View in: PubMed
    Score: 0.007
  24. High-coverage nanopore sequencing of samples from the 1000 Genomes Project to build a comprehensive catalog of human genetic variation. Genome Res. 2024 Nov 20; 34(11):2061-2073.
    View in: PubMed
    Score: 0.007
  25. Leveraging the T2T assembly to resolve rare and pathogenic inversions in reference genome gaps. Genome Res. 2024 Nov 20; 34(11):1785-1797.
    View in: PubMed
    Score: 0.007
  26. The GIAB genomic stratifications resource for human reference genomes. Nat Commun. 2024 Oct 19; 15(1):9029.
    View in: PubMed
    Score: 0.007
  27. When less is more: sketching with minimizers in genomics. Genome Biol. 2024 Oct 14; 25(1):270.
    View in: PubMed
    Score: 0.007
  28. Long-read sequencing of an advanced cancer cohort resolves rearrangements, unravels haplotypes, and reveals methylation landscapes. Cell Genom. 2024 Nov 13; 4(11):100674.
    View in: PubMed
    Score: 0.007
  29. StratoMod: predicting sequencing and variant calling errors with interpretable machine learning. Commun Biol. 2024 Oct 13; 7(1):1316.
    View in: PubMed
    Score: 0.007
  30. Single-cell somatic copy number variants in brain using different amplification methods and reference genomes. Commun Biol. 2024 Oct 09; 7(1):1288.
    View in: PubMed
    Score: 0.007
  31. Unveiling novel genetic variants in 370 challenging medically relevant genes using the long read sequencing data of 41 samples from 19 global populations. Mol Genet Genomics. 2024 Jul 07; 299(1):65.
    View in: PubMed
    Score: 0.006
  32. Inverted triplications formed by iterative template switches generate structural variant diversity at genomic disorder loci. Cell Genom. 2024 Jul 10; 4(7):100590.
    View in: PubMed
    Score: 0.006
  33. Germline structural variation globally impacts the cancer transcriptome including disease-relevant genes. Cell Rep Med. 2024 Mar 19; 5(3):101446.
    View in: PubMed
    Score: 0.006
  34. Characterization and visualization of tandem repeats at genome scale. Nat Biotechnol. 2024 Oct; 42(10):1606-1614.
    View in: PubMed
    Score: 0.006
  35. Scalable Nanopore sequencing of human genomes provides a comprehensive view of haplotype-resolved variation and methylation. Nat Methods. 2023 10; 20(10):1483-1492.
    View in: PubMed
    Score: 0.006
  36. The complete sequence of a human Y chromosome. Nature. 2023 Sep; 621(7978):344-354.
    View in: PubMed
    Score: 0.006
  37. Beyond the exome: What's next in diagnostic testing for Mendelian conditions. Am J Hum Genet. 2023 08 03; 110(8):1229-1248.
    View in: PubMed
    Score: 0.006
  38. Multiscale analysis of pangenomes enables improved representation of genomic diversity for repetitive and clinically relevant genes. Nat Methods. 2023 08; 20(8):1213-1221.
    View in: PubMed
    Score: 0.006
  39. Variant calling and benchmarking in an era of complete human genome sequences. Nat Rev Genet. 2023 Jul; 24(7):464-483.
    View in: PubMed
    Score: 0.006
  40. Intratumoral Heterogeneity and Clonal Evolution Induced by HPV Integration. Cancer Discov. 2023 04 03; 13(4):910-927.
    View in: PubMed
    Score: 0.006
  41. Genome-Wide Analysis of Structural Variants in Parkinson Disease. Ann Neurol. 2023 05; 93(5):1012-1022.
    View in: PubMed
    Score: 0.006
  42. A biallelic frameshift indel in PPP1R35 as a cause of primary microcephaly. Am J Med Genet A. 2023 03; 191(3):794-804.
    View in: PubMed
    Score: 0.006
  43. Whole genome sequencing identifies structural variants contributing to hematologic traits in the NHLBI TOPMed program. Nat Commun. 2022 12 08; 13(1):7592.
    View in: PubMed
    Score: 0.006
  44. The multiple de novo copy number variant (MdnCNV) phenomenon presents with peri-zygotic DNA mutational signatures and multilocus pathogenic variation. Genome Med. 2022 10 27; 14(1):122.
    View in: PubMed
    Score: 0.006
  45. Long read sequencing and expression studies of AHDC1 deletions in Xia-Gibbs syndrome reveal a novel genetic regulatory mechanism. Hum Mutat. 2022 12; 43(12):2033-2053.
    View in: PubMed
    Score: 0.006
  46. Multiple genome alignment in the telomere-to-telomere assembly era. Genome Biol. 2022 08 29; 23(1):182.
    View in: PubMed
    Score: 0.006
  47. Comprehensive short and long read sequencing analysis for the Gaucher and Parkinson's disease-associated GBA gene. Commun Biol. 2022 07 06; 5(1):670.
    View in: PubMed
    Score: 0.006
  48. The third international hackathon for applying insights into large-scale genomic composition to use cases in a wide range of organisms. F1000Res. 2022; 11:530.
    View in: PubMed
    Score: 0.006
  49. TOP-LD: A tool to explore linkage disequilibrium with TOPMed whole-genome sequence data. Am J Hum Genet. 2022 06 02; 109(6):1175-1181.
    View in: PubMed
    Score: 0.006
  50. Searching thousands of genomes to classify somatic and novel structural variants using STIX. Nat Methods. 2022 04; 19(4):445-448.
    View in: PubMed
    Score: 0.005
  51. A complete reference genome improves analysis of human genetic variation. Science. 2022 04; 376(6588):eabl3533.
    View in: PubMed
    Score: 0.005
  52. The complete sequence of a human genome. Science. 2022 04; 376(6588):44-53.
    View in: PubMed
    Score: 0.005
  53. Accelerated identification of disease-causing variants with ultra-rapid nanopore genome sequencing. Nat Biotechnol. 2022 07; 40(7):1035-1041.
    View in: PubMed
    Score: 0.005
  54. Rescuing low frequency variants within intra-host viral populations directly from Oxford Nanopore sequencing data. Nat Commun. 2022 03 14; 13(1):1321.
    View in: PubMed
    Score: 0.005
  55. Ultra-Rapid Nanopore Whole Genome Genetic Diagnosis of Dilated Cardiomyopathy in an Adolescent With Cardiogenic Shock. Circ Genom Precis Med. 2022 04; 15(2):e003591.
    View in: PubMed
    Score: 0.005
  56. Curated variation benchmarks for challenging medically relevant autosomal genes. Nat Biotechnol. 2022 05; 40(5):672-680.
    View in: PubMed
    Score: 0.005
  57. Ultrarapid Nanopore Genome Sequencing in a Critical Care Setting. N Engl J Med. 2022 02 17; 386(7):700-702.
    View in: PubMed
    Score: 0.005
  58. Assessing reproducibility of inherited variants detected with short-read whole genome sequencing. Genome Biol. 2022 01 03; 23(1):2.
    View in: PubMed
    Score: 0.005
  59. High resolution copy number inference in cancer using short-molecule nanopore sequencing. Nucleic Acids Res. 2021 12 02; 49(21):e124.
    View in: PubMed
    Score: 0.005
  60. Accurate profiling of forensic autosomal STRs using the Oxford Nanopore Technologies MinION device. Forensic Sci Int Genet. 2022 01; 56:102629.
    View in: PubMed
    Score: 0.005
  61. Investigation of product-derived lymphoma following infusion of piggyBac-modified CD19 chimeric antigen receptor T cells. Blood. 2021 10 21; 138(16):1391-1405.
    View in: PubMed
    Score: 0.005
  62. Vulcan: Improved long-read mapping and structural variant calling via dual-mode alignment. Gigascience. 2021 09 24; 10(9).
    View in: PubMed
    Score: 0.005
  63. Performance assessment of DNA sequencing platforms in the ABRF Next-Generation Sequencing Study. Nat Biotechnol. 2021 09; 39(9):1129-1140.
    View in: PubMed
    Score: 0.005
  64. Oligonucleotide capture sequencing of the SARS-CoV-2 genome and subgenomic fragments from COVID-19 individuals. PLoS One. 2021; 16(8):e0244468.
    View in: PubMed
    Score: 0.005
  65. Intronic Haplotypes in the GBA Gene Do Not Predict Age at Diagnosis of Parkinson's Disease. Mov Disord. 2021 06; 36(6):1456-1460.
    View in: PubMed
    Score: 0.005
  66. muCNV: Genotyping Structural Variants for Population-level Sequencing. Bioinformatics. 2021 08 04; 37(14):2055?2057.
    View in: PubMed
    Score: 0.005
  67. Shotgun transcriptome, spatial omics, and isothermal profiling of SARS-CoV-2 infection reveals unique host responses, viral diversification, and drug interactions. Nat Commun. 2021 03 12; 12(1):1660.
    View in: PubMed
    Score: 0.005
  68. SARS-CoV-2 genomic diversity and the implications for qRT-PCR diagnostics and transmission. Genome Res. 2021 04; 31(4):635-644.
    View in: PubMed
    Score: 0.005
  69. Chromosome-scale, haplotype-resolved assembly of human genomes. Nat Biotechnol. 2021 03; 39(3):309-312.
    View in: PubMed
    Score: 0.005
  70. Simultaneous profiling of chromatin accessibility and methylation on human cell lines with nanopore sequencing. Nat Methods. 2020 12; 17(12):1191-1199.
    View in: PubMed
    Score: 0.005
  71. Complex mosaic structural variations in human fetal brains. Genome Res. 2020 12; 30(12):1695-1704.
    View in: PubMed
    Score: 0.005
  72. A diploid assembly-based benchmark for variants in the major histocompatibility complex. Nat Commun. 2020 09 22; 11(1):4794.
    View in: PubMed
    Score: 0.005
  73. Comprehensive analysis of structural variants in breast cancer genomes using single-molecule sequencing. Genome Res. 2020 09; 30(9):1258-1273.
    View in: PubMed
    Score: 0.005
  74. A robust benchmark for detection of germline large deletions and insertions. Nat Biotechnol. 2020 11; 38(11):1347-1355.
    View in: PubMed
    Score: 0.005
  75. Nanopore sequencing and the Shasta toolkit enable efficient de novo assembly of eleven human genomes. Nat Biotechnol. 2020 09; 38(9):1044-1053.
    View in: PubMed
    Score: 0.005
  76. Targeted nanopore sequencing with Cas9-guided adapter ligation. Nat Biotechnol. 2020 04; 38(4):433-438.
    View in: PubMed
    Score: 0.005
  77. Potential applications of nanopore sequencing for forensic analysis. Forensic Sci Rev. 2020 Jan; 32(1):23-54.
    View in: PubMed
    Score: 0.005
  78. Paragraph: a graph-based structural variant genotyper for short-read sequence data. Genome Biol. 2019 12 19; 20(1):291.
    View in: PubMed
    Score: 0.005
  79. Approaches to Whole Mitochondrial Genome Sequencing on the Oxford Nanopore MinION. Curr Protoc Hum Genet. 2019 12; 104(1):e94.
    View in: PubMed
    Score: 0.005
  80. Structural variant calling: the long and the short of it. Genome Biol. 2019 11 20; 20(1):246.
    View in: PubMed
    Score: 0.005
  81. A Genocentric Approach to Discovery of Mendelian Disorders. Am J Hum Genet. 2019 11 07; 105(5):974-986.
    View in: PubMed
    Score: 0.005
  82. Accurate circular consensus long-read sequencing improves variant detection and assembly of a human genome. Nat Biotechnol. 2019 10; 37(10):1155-1162.
    View in: PubMed
    Score: 0.005
  83. Atlas-CNV: a validated approach to call single-exon CNVs in the eMERGESeq gene panel. Genet Med. 2019 09; 21(9):2135-2144.
    View in: PubMed
    Score: 0.004
  84. A multi-task convolutional deep neural network for variant calling in single molecule sequencing. Nat Commun. 2019 03 01; 10(1):998.
    View in: PubMed
    Score: 0.004
  85. Megabase Length Hypermutation Accompanies Human Structural Variation at 17p11.2. Cell. 2019 03 07; 176(6):1310-1324.e10.
    View in: PubMed
    Score: 0.004
  86. Evaluation of the detection of GBA missense mutations and other variants using the Oxford Nanopore MinION. Mol Genet Genomic Med. 2019 03; 7(3):e564.
    View in: PubMed
    Score: 0.004
  87. Complex rearrangements and oncogene amplifications revealed by long-read DNA and RNA sequencing of a breast cancer cell line. Genome Res. 2018 08; 28(8):1126-1135.
    View in: PubMed
    Score: 0.004
  88. Phased diploid genome assembly with single-molecule real-time sequencing. Nat Methods. 2016 Dec; 13(12):1050-1054.
    View in: PubMed
    Score: 0.004
  89. ADAR2 induces reproducible changes in sequence and abundance of mature microRNAs in the mouse brain. Nucleic Acids Res. 2014 Oct 29; 42(19):12155-68.
    View in: PubMed
    Score: 0.003
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.