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Connection

CHRIS AMOS to Genetic Predisposition to Disease

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This is a "connection" page, showing publications CHRIS AMOS has written about Genetic Predisposition to Disease.
CHRIS AMOS
Connection Strength
5.125
Genetic Predisposition to Disease
  1. The OncoArray Consortium: A Network for Understanding the Genetic Architecture of Common Cancers. Cancer Epidemiol Biomarkers Prev. 2017 01; 26(1):126-135.
    View in: PubMed
    Score: 0.377
  2. Fine-mapping of the 5p15.33, 6p22.1-p21.31, and 15q25.1 regions identifies functional and histology-specific lung cancer susceptibility loci in African-Americans. Cancer Epidemiol Biomarkers Prev. 2013 Feb; 22(2):251-60.
    View in: PubMed
    Score: 0.289
  3. Genome-wide association study identifies novel loci predisposing to cutaneous melanoma. Hum Mol Genet. 2011 Dec 15; 20(24):5012-23.
    View in: PubMed
    Score: 0.266
  4. Ordered subset analysis identifies loci influencing lung cancer risk on chromosomes 6q and 12q. Cancer Epidemiol Biomarkers Prev. 2010 Dec; 19(12):3157-66.
    View in: PubMed
    Score: 0.250
  5. Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1. Nat Genet. 2008 May; 40(5):616-22.
    View in: PubMed
    Score: 0.209
  6. Genome-wide association study for lung cancer in 6531 African Americans reveals new susceptibility loci. Hum Mol Genet. 2025 Jul 03; 34(14):1227-1237.
    View in: PubMed
    Score: 0.173
  7. Cross-ancestry genome-wide meta-analysis of 61,047 cases and 947,237 controls identifies new susceptibility loci contributing to lung cancer. Nat Genet. 2022 08; 54(8):1167-1177.
    View in: PubMed
    Score: 0.141
  8. Genetic Variation and Recurrent Haplotypes on Chromosome 6q23-25 Risk Locus in Familial Lung Cancer. Cancer Res. 2021 06 15; 81(12):3162-3173.
    View in: PubMed
    Score: 0.129
  9. A Genome-Wide Association Study Identifies Two Novel Susceptible Regions for Squamous Cell Carcinoma of the Head and Neck. Cancer Res. 2020 06 15; 80(12):2451-2460.
    View in: PubMed
    Score: 0.120
  10. Whole Exome Sequencing of Highly Aggregated Lung Cancer Families Reveals Linked Loci for Increased Cancer Risk on Chromosomes 12q, 7p, and 4q. Cancer Epidemiol Biomarkers Prev. 2020 02; 29(2):434-442.
    View in: PubMed
    Score: 0.117
  11. Fine mapping of MHC region in lung cancer highlights independent susceptibility loci by ethnicity. Nat Commun. 2018 09 25; 9(1):3927.
    View in: PubMed
    Score: 0.108
  12. Genome-wide association study of familial lung cancer. Carcinogenesis. 2018 09 21; 39(9):1135-1140.
    View in: PubMed
    Score: 0.108
  13. Identification of susceptibility pathways for the role of chromosome 15q25.1 in modifying lung cancer risk. Nat Commun. 2018 08 13; 9(1):3221.
    View in: PubMed
    Score: 0.107
  14. Genome-wide association study of glioma subtypes identifies specific differences in genetic susceptibility to glioblastoma and non-glioblastoma tumors. Nat Genet. 2017 May; 49(5):789-794.
    View in: PubMed
    Score: 0.097
  15. Focused Analysis of Exome Sequencing Data for Rare Germline Mutations in Familial and Sporadic Lung Cancer. J Thorac Oncol. 2016 Jan; 11(1):52-61.
    View in: PubMed
    Score: 0.089
  16. The role of haplotype in 15q25.1 locus in lung cancer risk: results of scanning chromosome 15. Carcinogenesis. 2015 Nov; 36(11):1275-83.
    View in: PubMed
    Score: 0.087
  17. A recurrent mutation in PARK2 is associated with familial lung cancer. Am J Hum Genet. 2015 Feb 05; 96(2):301-8.
    View in: PubMed
    Score: 0.084
  18. Informed genome-wide association analysis with family history as a secondary phenotype identifies novel loci of lung cancer. Genet Epidemiol. 2015 Mar; 39(3):197-206.
    View in: PubMed
    Score: 0.084
  19. SNP characteristics predict replication success in association studies. Hum Genet. 2014 Dec; 133(12):1477-86.
    View in: PubMed
    Score: 0.082
  20. Joint effect of multiple common SNPs predicts melanoma susceptibility. PLoS One. 2013; 8(12):e85642.
    View in: PubMed
    Score: 0.078
  21. Genome-wide association study of dermatomyositis reveals genetic overlap with other autoimmune disorders. Arthritis Rheum. 2013 Dec; 65(12):3239-47.
    View in: PubMed
    Score: 0.077
  22. Natural and orthogonal model for estimating gene-gene interactions applied to cutaneous melanoma. Hum Genet. 2014 May; 133(5):559-74.
    View in: PubMed
    Score: 0.077
  23. Association between putative functional variants in the PSMB9 gene and risk of melanoma--re-analysis of published melanoma genome-wide association studies. Pigment Cell Melanoma Res. 2013 May; 26(3):392-401.
    View in: PubMed
    Score: 0.074
  24. A variant in FTO shows association with melanoma risk not due to BMI. Nat Genet. 2013 Apr; 45(4):428-32, 432e1.
    View in: PubMed
    Score: 0.073
  25. Variants in melanocortin 1 receptor gene contribute to risk of melanoma--a direct sequencing analysis in a Texas population. Pigment Cell Melanoma Res. 2013 May; 26(3):422-5.
    View in: PubMed
    Score: 0.073
  26. Insight in glioma susceptibility through an analysis of 6p22.3, 12p13.33-12.1, 17q22-23.2 and 18q23 SNP genotypes in familial and non-familial glioma. Hum Genet. 2012 Sep; 131(9):1507-17.
    View in: PubMed
    Score: 0.070
  27. Derived SNP alleles are used more frequently than ancestral alleles as risk-associated variants in common human diseases. J Bioinform Comput Biol. 2012 Apr; 10(2):1241008.
    View in: PubMed
    Score: 0.069
  28. Exonuclease 1 (EXO1) gene variation and melanoma risk. DNA Repair (Amst). 2012 Mar 01; 11(3):304-9.
    View in: PubMed
    Score: 0.068
  29. A case-control study of a sex-specific association between a 15q25 variant and lung cancer risk. Cancer Epidemiol Biomarkers Prev. 2011 Dec; 20(12):2603-9.
    View in: PubMed
    Score: 0.067
  30. Genome-wide association study identifies three new melanoma susceptibility loci. Nat Genet. 2011 Oct 09; 43(11):1108-13.
    View in: PubMed
    Score: 0.067
  31. Novel genetic variants in the chromosome 5p15.33 region associate with lung cancer risk. Carcinogenesis. 2011 Oct; 32(10):1493-9.
    View in: PubMed
    Score: 0.066
  32. Genome-wide association study identifies novel alleles associated with risk of cutaneous basal cell carcinoma and squamous cell carcinoma. Hum Mol Genet. 2011 Sep 15; 20(18):3718-24.
    View in: PubMed
    Score: 0.065
  33. Genome-wide association study identifies nidogen 1 (NID1) as a susceptibility locus to cutaneous nevi and melanoma risk. Hum Mol Genet. 2011 Jul 01; 20(13):2673-9.
    View in: PubMed
    Score: 0.064
  34. A genome-wide association study identifies a locus on chromosome 14q21 as a predictor of leukocyte telomere length and as a marker of susceptibility for bladder cancer. Cancer Prev Res (Phila). 2011 Apr; 4(4):514-21.
    View in: PubMed
    Score: 0.064
  35. Forward-time simulation of realistic samples for genome-wide association studies. BMC Bioinformatics. 2010 Sep 01; 11:442.
    View in: PubMed
    Score: 0.062
  36. Nicotinic acetylcholine receptor region on chromosome 15q25 and lung cancer risk among African Americans: a case-control study. J Natl Cancer Inst. 2010 Aug 04; 102(15):1199-205.
    View in: PubMed
    Score: 0.061
  37. A susceptibility locus on chromosome 6q greatly increases lung cancer risk among light and never smokers. Cancer Res. 2010 Mar 15; 70(6):2359-67.
    View in: PubMed
    Score: 0.060
  38. Genetic variation in the prostate stem cell antigen gene PSCA confers susceptibility to urinary bladder cancer. Nat Genet. 2009 Sep; 41(9):991-5.
    View in: PubMed
    Score: 0.057
  39. Common 5p15.33 and 6p21.33 variants influence lung cancer risk. Nat Genet. 2008 Dec; 40(12):1407-9.
    View in: PubMed
    Score: 0.054
  40. PNPLA3, Obesity, and Heavy Alcohol Use in Cirrhosis Patients May Exert a Synergistic Increase Hepatocellular Carcinoma Risk. Clin Gastroenterol Hepatol. 2024 Sep; 22(9):1858-1866.e4.
    View in: PubMed
    Score: 0.040
  41. Genetic susceptibility to lung cancer: the role of DNA damage and repair. Cancer Epidemiol Biomarkers Prev. 2003 Aug; 12(8):689-98.
    View in: PubMed
    Score: 0.038
  42. Genetic susceptibility for lung cancer: interactions with gender and smoking history and impact on early detection policies. Hum Hered. 2003; 56(1-3):139-45.
    View in: PubMed
    Score: 0.036
  43. Genome-wide interaction analysis identified low-frequency variants with sex disparity in lung cancer risk. Hum Mol Genet. 2022 08 23; 31(16):2831-2843.
    View in: PubMed
    Score: 0.035
  44. The association of microsomal epoxide hydrolase polymorphisms and lung cancer risk in African-Americans and Mexican-Americans. Carcinogenesis. 2001 Jun; 22(6):923-8.
    View in: PubMed
    Score: 0.033
  45. Age-associated risk of cancer among individuals with N-acetyltransferase 2 (NAT2) mutations and mutations in DNA mismatch repair genes. Cancer Res. 2001 Feb 15; 61(4):1269-71.
    View in: PubMed
    Score: 0.032
  46. Lung Cancer Risk in Never-Smokers of European Descent is Associated With Genetic Variation in the 5p15.33 TERT-CLPTM1Ll Region. J Thorac Oncol. 2019 08; 14(8):1360-1369.
    View in: PubMed
    Score: 0.028
  47. Genome-wide interaction study of smoking behavior and non-small cell lung cancer risk in Caucasian population. Carcinogenesis. 2018 03 08; 39(3):336-346.
    View in: PubMed
    Score: 0.026
  48. Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes. Nat Genet. 2017 Jul; 49(7):1126-1132.
    View in: PubMed
    Score: 0.025
  49. Fine mapping of chromosome 5p15.33 based on a targeted deep sequencing and high density genotyping identifies novel lung cancer susceptibility loci. Carcinogenesis. 2016 Jan; 37(1):96-105.
    View in: PubMed
    Score: 0.022
  50. Identification of lung cancer histology-specific variants applying Bayesian framework variant prioritization approaches within the TRICL and ILCCO consortia. Carcinogenesis. 2015 Nov; 36(11):1314-26.
    View in: PubMed
    Score: 0.022
  51. Genome-wide association study identifies HLA 8.1 ancestral haplotype alleles as major genetic risk factors for myositis phenotypes. Genes Immun. 2015 Oct; 16(7):470-80.
    View in: PubMed
    Score: 0.022
  52. Germline mutations in shelterin complex genes are associated with familial glioma. J Natl Cancer Inst. 2015 Jan; 107(1):384.
    View in: PubMed
    Score: 0.021
  53. Identification of a melanoma susceptibility locus and somatic mutation in TET2. Carcinogenesis. 2014 Sep; 35(9):2097-101.
    View in: PubMed
    Score: 0.020
  54. Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer. Nat Genet. 2014 Jul; 46(7):736-41.
    View in: PubMed
    Score: 0.020
  55. A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry. Nat Genet. 2013 Jun; 45(6):690-6.
    View in: PubMed
    Score: 0.019
  56. Role of selected genetic variants in lung cancer risk in African Americans. J Thorac Oncol. 2013 Apr; 8(4):391-7.
    View in: PubMed
    Score: 0.018
  57. Genome-wide association studies identify several new loci associated with pigmentation traits and skin cancer risk in European Americans. Hum Mol Genet. 2013 Jul 15; 22(14):2948-59.
    View in: PubMed
    Score: 0.018
  58. Association between functional polymorphisms in genes involved in the MAPK signaling pathways and cutaneous melanoma risk. Carcinogenesis. 2013 Apr; 34(4):885-92.
    View in: PubMed
    Score: 0.018
  59. On the interplay of telomeres, nevi and the risk of melanoma. PLoS One. 2012; 7(12):e52466.
    View in: PubMed
    Score: 0.018
  60. Identification of the NF-?B activating protein-like locus as a risk locus for rheumatoid arthritis. Ann Rheum Dis. 2013 Jul; 72(7):1249-54.
    View in: PubMed
    Score: 0.018
  61. PGC-1 coactivators regulate MITF and the tanning response. Mol Cell. 2013 Jan 10; 49(1):145-57.
    View in: PubMed
    Score: 0.018
  62. Association study of nicotinic acetylcholine receptor genes identifies a novel lung cancer susceptibility locus near CHRNA1 in African-Americans. Oncotarget. 2012 Nov; 3(11):1428-38.
    View in: PubMed
    Score: 0.018
  63. Immunochip analyses identify a novel risk locus for primary biliary cirrhosis at 13q14, multiple independent associations at four established risk loci and epistasis between 1p31 and 7q32 risk variants. Hum Mol Genet. 2012 Dec 01; 21(23):5209-21.
    View in: PubMed
    Score: 0.018
  64. Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers. Arch Gen Psychiatry. 2012 Aug; 69(8):854-60.
    View in: PubMed
    Score: 0.018
  65. No association between Parkinson disease alleles and the risk of melanoma. Cancer Epidemiol Biomarkers Prev. 2012 Jan; 21(1):243-5.
    View in: PubMed
    Score: 0.017
  66. Variants in inflammation genes are implicated in risk of lung cancer in never smokers exposed to second-hand smoke. Cancer Discov. 2011 Oct; 1(5):420-9.
    View in: PubMed
    Score: 0.017
  67. Susceptibility locus for lung cancer at 15q25.1 is not associated with risk of pancreatic cancer. Pancreas. 2011 Aug; 40(6):872-5.
    View in: PubMed
    Score: 0.016
  68. An analysis of single nucleotide polymorphisms of 125 DNA repair genes in the Texas genome-wide association study of lung cancer with a replication for the XRCC4 SNPs. DNA Repair (Amst). 2011 Apr 03; 10(4):398-407.
    View in: PubMed
    Score: 0.016
  69. A genetic variant near the PMAIP1/Noxa gene is associated with increased bleomycin sensitivity. Hum Mol Genet. 2011 Feb 15; 20(4):820-6.
    View in: PubMed
    Score: 0.016
  70. Replication of lung cancer susceptibility loci at chromosomes 15q25, 5p15, and 6p21: a pooled analysis from the International Lung Cancer Consortium. J Natl Cancer Inst. 2010 Jul 07; 102(13):959-71.
    View in: PubMed
    Score: 0.015
  71. Primary biliary cirrhosis associated with HLA, IL12A, and IL12RB2 variants. N Engl J Med. 2009 Jun 11; 360(24):2544-55.
    View in: PubMed
    Score: 0.014
  72. CTLA4/ICOS gene variants and haplotypes are associated with rheumatoid arthritis and primary biliary cirrhosis in the Canadian population. Arthritis Rheum. 2009 Apr; 60(4):931-7.
    View in: PubMed
    Score: 0.014
  73. The CHRNA5-A3 region on chromosome 15q24-25.1 is a risk factor both for nicotine dependence and for lung cancer. J Natl Cancer Inst. 2008 Nov 05; 100(21):1552-6.
    View in: PubMed
    Score: 0.014
  74. Familial aggregation of common sequence variants on 15q24-25.1 in lung cancer. J Natl Cancer Inst. 2008 Sep 17; 100(18):1326-30.
    View in: PubMed
    Score: 0.013
  75. Mitochondrial DNA content: its genetic heritability and association with renal cell carcinoma. J Natl Cancer Inst. 2008 Aug 06; 100(15):1104-12.
    View in: PubMed
    Score: 0.013
  76. Mutagen sensitivity has high heritability: evidence from a twin study. Cancer Res. 2006 Jun 15; 66(12):5993-6.
    View in: PubMed
    Score: 0.012
  77. Bladder cancer predisposition: a multigenic approach to DNA-repair and cell-cycle-control genes. Am J Hum Genet. 2006 Mar; 78(3):464-79.
    View in: PubMed
    Score: 0.011
  78. In vitro sensitivity to ultraviolet B light and skin cancer risk: a case-control analysis. J Natl Cancer Inst. 2005 Dec 21; 97(24):1822-31.
    View in: PubMed
    Score: 0.011
  79. p73 G4C14-to-A4T14 polymorphism and risk of lung cancer. Cancer Res. 2004 Oct 01; 64(19):6863-6.
    View in: PubMed
    Score: 0.010
  80. Association of a p73 exon 2 G4C14-to-A4T14 polymorphism with risk of squamous cell carcinoma of the head and neck. Carcinogenesis. 2004 Oct; 25(10):1911-6.
    View in: PubMed
    Score: 0.010
  81. An evolutionary perspective on single-nucleotide polymorphism screening in molecular cancer epidemiology. Cancer Res. 2004 Mar 15; 64(6):2251-7.
    View in: PubMed
    Score: 0.010
  82. Telomere dysfunction: a potential cancer predisposition factor. J Natl Cancer Inst. 2003 Aug 20; 95(16):1211-8.
    View in: PubMed
    Score: 0.009
  83. Repair of UV light-induced DNA damage and risk of cutaneous malignant melanoma. J Natl Cancer Inst. 2003 Feb 19; 95(4):308-15.
    View in: PubMed
    Score: 0.009
  84. Associations among telomerase activity, p53 protein overexpression, and genetic instability in lung cancer. Br J Cancer. 1999 May; 80(3-4):453-7.
    View in: PubMed
    Score: 0.007
  85. Mutagen sensitivity as a biological marker of lung cancer risk in African Americans. Cancer Epidemiol Biomarkers Prev. 1995 Mar; 4(2):99-103.
    View in: PubMed
    Score: 0.005
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.