DONGLUDONG LU13461LU, DONGprns:coAuthorOfcoauthor ofFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressvivo:address1address line 1vivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provincevivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentDivisionvivo:hasResearchArearesearch areasvivo:hrJobTitleHR job titleInformation Resourcevivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonBreast Medical OncologyLeukemiaMolecular & Cellular OncologySystems BiologyMD AndersonMIEN-CHIEHUNGMIEN-CHIE HUNG8427HUNG, MIEN-CHIEProfessorJORGE ECORTESJORGE E CORTES8637CORTES, JORGE EProfessorHAGOP MKANTARJIANHAGOP M KANTARJIAN8501KANTARJIAN, HAGOP MProfessorGORDON BMILLSGORDON B MILLS8620MILLS, GORDON BProfessorAMAN UBUZDARAMAN U BUZDAR8609BUZDAR, AMAN UProfessor74Professor10Assistant Professor53Graduate StudentOne Baylor PlazaHouston, 77030TX0.7288330.0055297158research areas0.3386830.037541123coauthor of7.5161.0749460similar to118selected publicationsD044767Chemicals & Drugs4618560.659656Ubiquitin-Protein LigasesD055808Procedures2193220.788817Drug Discovery27959613Finn RS, Martin M, Rugo HS, Jones S, Im SA, Gelmon K, Harbeck N, Lipatov ON, Walshe JM, Moulder S, Gauthier E, Lu DR, Randolph S, Di?ras V, Slamon DJThe New England journal of medicinePalbociclib and Letrozole in Advanced Breast Cancer. N Engl J Med. 2016 11 17; 375(20):1925-1936.N Engl J Med2016-11-17T00:00:002016Palbociclib and Letrozole in Advanced Breast Cancer.Department of Molecular & Cellular BiologyMolecular & Cellular BiologyBaylor College of MedicineDAVIDLONARDDAVID LONARD0.000000000000000.000000000000003522LONARD, DAVIDProfessorD00007470247520.929624ProteostasisD00007624942510.963101Heat Shock Transcription FactorsD059748Physiology2613720.833636ProteolysisChemical, Physical & Structural BiologyXIAOLIQIXIAOLI QI14762QI, XIAOLIAssistant Professor71Postdoc Fellows and AssociatesPostDocAuthorship 998073832848159Guo WH, Qi X, Yu X, Liu Y, Chung CI, Bai F, Lin X, Lu D, Wang L, Chen J, Su LH, Nomie KJ, Li F, Wang MC, Shu X, Onuchic JN, Woyach JA, Wang ML, Wang JNature communicationsEnhancing intracellular accumulation and target engagement of PROTACs with reversible covalent chemistry. Nat Commun. 2020 08 26; 11(1):4268.Nat Commun2020-08-26T00:00:002020Enhancing intracellular accumulation and target engagement of PROTACs with reversible covalent chemistry.true1Postdoc Fellows and AssociatesPostdoc Fellows and AssociatesRishiPaudelRishi Ram Paudel16411Paudel, RishiPostdoc Fellows and Associatestrue1Graduate StudentGraduate StudentErikaMonroyErika Yvonne Monroy16742Monroy, ErikaGraduate StudentAuthorship 1026208334310341Qin L, Chen J, Lu D, Jain P, Yu Y, Cardenas D, Peng X, Yu X, Xu J, Wang J, O'Malley BW, Lonard DMEndocrine-related cancerDevelopment of improved SRC-3 inhibitors as breast cancer therapeutic agents. Endocr Relat Cancer. 2021 08 13; 28(10):657-670.Endocr Relat Cancer2021-08-13T00:00:002021Development of improved SRC-3 inhibitors as breast cancer therapeutic agents.Authorship 102769512true1Postdoc Fellows and AssociatesPostdoc Fellows and AssociatesRanChengRan Cheng17180Cheng, RanPostdoc Fellows and AssociatesAuthorship 10567342Authorship 1060238136285735Lu D, Yu X, Lin H, Cheng R, Monroy EY, Qi X, Wang MC, Wang JChemical Society reviewsApplications of covalent chemistry in targeted protein degradation. Chem Soc Rev. 2022 Nov 14; 51(22):9243-9261.Chem Soc Rev2022-11-14T00:00:002022Applications of covalent chemistry in targeted protein degradation.36130224Paudel RR, Lu D, Roy Chowdhury S, Monroy EY, Wang JBiochemistryTargeted Protein Degradation via Lysosomes. Biochemistry. 2023 02 07; 62(3):564-579.Biochemistry2022-09-21T00:00:002022Targeted Protein Degradation via Lysosomes.Authorship 1063057836712232Yu X, Guo WH, Lin H, Cheng R, Monroy EY, Jin F, Ding L, Lu D, Qi X, Wang MC, Wang JCurrent research in chemical biologyDiscovery of a potent BTK and IKZF1/3 triple degrader through reversible covalent BTK PROTAC development. Curr Res Chem Biol. 2022; 2.Curr Res Chem Biol2022-05-17T00:00:002022Discovery of a potent BTK and IKZF1/3 triple degrader through reversible covalent BTK PROTAC development.36945511Bijou I, Liu Y, Lu D, Chen J, Sloan S, Alinari L, Lonard DM, O'Malley BW, Wang M, Wang JResearch squareInhibition of SRC-3 as a potential therapeutic strategy for aggressive mantle cell lymphoma. Res Sq. 2023 Mar 10.Res Sq2023-03-10T00:00:002023Inhibition of SRC-3 as a potential therapeutic strategy for aggressive mantle cell lymphoma.true1Assistant ProfessorAssistant ProfessorDepartment of Biochemistry and Molecular PharmacologyBiochemistry & Mol PharmacologyAuthorship 1078886837676964Lv X, Lu X, Cao J, Luo Q, Ding Y, Peng F, Pataer A, Lu D, Han D, Malmberg E, Chan DW, Wang X, Savage SR, Mao S, Yu J, Peng F, Yan L, Meng H, Maneix L, Han Y, Chen Y, Yao W, Chang EC, Catic A, Lin X, Miles G, Huang P, Sun Z, Burt B, Wang H, Wang J, Yao QC, Zhang B, Roth JA, O'Malley BW, Ellis MJ, Rimawi MF, Ying H, Chen XScience (New York, N.Y.)Modulation of the proteostasis network promotes tumor resistance to oncogenic KRAS inhibitors. Science. 2023 09 08; 381(6662):eabn4180.Science2023-09-08T00:00:002023Modulation of the proteostasis network promotes tumor resistance to oncogenic KRAS inhibitors.Authorship 10814673true1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessor