UDDALAKBHARADWAJUDDALAK BHARADWAJ11942BHARADWAJ, UDDALAKAssistant Professorprns:coAuthorOfcoauthor ofFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressvivo:address1address line 1vivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provincevivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentDivisionvivo:hasResearchArearesearch areasvivo:hrJobTitleHR job titleInformation Resourcevivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:personInPositionpositionsPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonInfectious Diseases, Infection Control, and Employee HealthLeukemiaMolecular & Cellular OncologySystems BiologyMD AndersonMIEN-CHIEHUNGMIEN-CHIE HUNG8427HUNG, MIEN-CHIEProfessorANIRBANMAITRAANIRBAN MAITRA9915MAITRA, ANIRBANProfessorHAGOP MKANTARJIANHAGOP M KANTARJIAN8501KANTARJIAN, HAGOP MProfessorGORDON BMILLSGORDON B MILLS8620MILLS, GORDON BProfessor26410177Lewis KM, Bharadwaj U, Eckols TK, Kolosov M, Kasembeli MM, Fridley C, Siller R, Tweardy DJLung cancer (Amsterdam, Netherlands)Small-molecule targeting of signal transducer and activator of transcription (STAT) 3 to treat non-small cell lung cancer. Lung Cancer. 2015 Nov; 90(2):182-90.Lung Cancer2015-09-15T00:00:002015Small-molecule targeting of signal transducer and activator of transcription (STAT) 3 to treat non-small cell lung cancer.26645674Yuan H, Houck KL, Tian Y, Bharadwaj U, Hull K, Zhou Z, Zhu M, Zhou M, Wu X, Tweardy DJ, Romo D, Fu X, Zhang Y, Zhang J, Dong JFPloS onePiperlongumine Blocks JAK2-STAT3 to Inhibit Collagen-Induced Platelet Reactivity Independent of Reactive Oxygen Species. PLoS One. 2015; 10(12):e0143964.PLoS One2015-12-08T00:00:002015Piperlongumine Blocks JAK2-STAT3 to Inhibit Collagen-Induced Platelet Reactivity Independent of Reactive Oxygen Species.12713150Agrawal S, M?ller B, Bharadwaj U, Bhatnagar S, Sharma A, Khan F, Agarwal SSHuman biologyMicrosatellite variation at 24 STR loci in three endogamous groups of Uttar Pradesh, India. Hum Biol. 2003 Feb; 75(1):97-104.Hum Biol2003-02-01T00:00:002003Microsatellite variation at 24 STR loci in three endogamous groups of Uttar Pradesh, India.12051365Agrawal S, M?ller B, Bharadwaj U, Bhatnagar S, Khan FJournal of forensic sciencesAllele frequencies of microsatellite repeat loci in Bhargavas, Chaturvedis, and Brahmins of North India. J Forensic Sci. 2002 May; 47(3):678-81.J Forensic Sci2002-05-01T00:00:002002Allele frequencies of microsatellite repeat loci in Bhargavas, Chaturvedis, and Brahmins of North India.12051366Agrawal S, M?ller B, Bharadwaj U, Bhatnagar S, Khan FJournal of forensic sciencesDistribution of allele frequencies of six STR markers in north Indians. J Forensic Sci. 2002 May; 47(3):682-5.J Forensic Sci2002-05-01T00:00:002002Distribution of allele frequencies of six STR markers in north Indians.74Professor10Assistant Professor14Associate Professor6767 Bertner StHouston77030-2603TXDAVIDTWEARDYDAVID TWEARDY11776TWEARDY, DAVIDProfessor1.602830.00724075288research areas3.871830.021092233coauthor of26.06756.0885360similar to1152selected publicationsMOSES MAKOKHAKASEMBELIMOSES MAKOKHA KASEMBELI11943KASEMBELI, MOSES MAKOKHAAssistant ProfessorPREMAROBINSONPREMA ROBINSON11944ROBINSON, PREMAAssociate Professor26981525Robinson P, Kasembeli M, Bharadwaj U, Engineer N, Eckols KT, Tweardy DJBioMed research internationalSubstance P Receptor Signaling Mediates Doxorubicin-Induced Cardiomyocyte Apoptosis and Triple-Negative Breast Cancer Chemoresistance. Biomed Res Int. 2016; 2016:1959270.Biomed Res Int2016-02-11T00:00:002016Substance P Receptor Signaling Mediates Doxorubicin-Induced Cardiomyocyte Apoptosis and Triple-Negative Breast Cancer Chemoresistance.27027445Bharadwaj U, Eckols TK, Xu X, Kasembeli MM, Chen Y, Adachi M, Song Y, Mo Q, Lai SY, Tweardy DJOncotargetSmall-molecule inhibition of STAT3 in radioresistant head and neck squamous cell carcinoma. Oncotarget. 2016 May 03; 7(18):26307-30.Oncotarget2016-05-03T00:00:002016Small-molecule inhibition of STAT3 in radioresistant head and neck squamous cell carcinoma.17118780Feurino LW, Fisher WE, Bharadwaj U, Yao Q, Chen C, Li MCancer investigationCurrent update of cytokines in pancreatic cancer: pathogenic mechanisms, clinical indication, and therapeutic values. Cancer Invest. 2006 Nov; 24(7):696-703.Cancer Invest2006-11-01T00:00:002006Current update of cytokines in pancreatic cancer: pathogenic mechanisms, clinical indication, and therapeutic values.17568185Feurino LW, Zhang Y, Bharadwaj U, Zhang R, Li F, Fisher WE, Brunicardi FC, Chen C, Yao Q, Min LCancer biology & therapyIL-6 stimulates Th2 type cytokine secretion and upregulates VEGF and NRP-1 expression in pancreatic cancer cells. Cancer Biol Ther. 2007 Jul; 6(7):1096-100.Cancer Biol Ther2007-07-01T00:00:002007IL-6 stimulates Th2 type cytokine secretion and upregulates VEGF and NRP-1 expression in pancreatic cancer cells.18003899Li M, Zhang Y, Liu Z, Bharadwaj U, Wang H, Wang X, Zhang S, Liuzzi JP, Chang SM, Cousins RJ, Fisher WE, Brunicardi FC, Logsdon CD, Chen C, Yao QProceedings of the National Academy of Sciences of the United States of AmericaAberrant expression of zinc transporter ZIP4 (SLC39A4) significantly contributes to human pancreatic cancer pathogenesis and progression. Proc Natl Acad Sci U S A. 2007 Nov 20; 104(47):18636-41.Proc Natl Acad Sci U S A2007-11-14T00:00:002007Aberrant expression of zinc transporter ZIP4 (SLC39A4) significantly contributes to human pancreatic cancer pathogenesis and progression.19755388Li M, Zhang Y, Bharadwaj U, Zhai QJ, Ahern CH, Fisher WE, Brunicardi FC, Logsdon CD, Chen C, Yao QClinical cancer research : an official journal of the American Association for Cancer ResearchDown-regulation of ZIP4 by RNA interference inhibits pancreatic cancer growth and increases the survival of nude mice with pancreatic cancer xenografts. Clin Cancer Res. 2009 Oct 01; 15(19):5993-6001.Clin Cancer Res2009-09-15T00:00:002009Down-regulation of ZIP4 by RNA interference inhibits pancreatic cancer growth and increases the survival of nude mice with pancreatic cancer xenografts.Authorship 3726573Authorship 3726581Authorship 3726593Authorship 3726602Authorship 3726619Authorship 3726622Authorship 3726632Authorship 3726643Authorship 3726652Authorship 3726669Authorship 3726674Authorship 3726683Authorship 3726693Authorship 3727802Authorship 3727811Authorship 3727821Authorship 3727832Authorship 3727843Authorship 3728061Authorship 3728464Authorship 3728473Authorship 3728483Authorship 3728493Authorship 3728502Authorship 3728514Authorship 3728521Authorship 372853415964302Bharadwaj U, Zhang R, Yang H, Li M, Doan LX, Chen C, Yao QThe Journal of surgical researchEffects of cyclophilin A on myeloblastic cell line KG-1 derived dendritic like cells (DLC) through p38 MAP kinase activation. J Surg Res. 2005 Jul 01; 127(1):29-38.J Surg Res2005-04-21T00:00:002005Effects of cyclophilin A on myeloblastic cell line KG-1 derived dendritic like cells (DLC) through p38 MAP kinase activation.17240359Aggarwal BB, Banerjee S, Bharadwaj U, Sung B, Shishodia S, Sethi GBiochemical pharmacologyCurcumin induces the degradation of cyclin E expression through ubiquitin-dependent pathway and up-regulates cyclin-dependent kinase inhibitors p21 and p27 in multiple human tumor cell lines. Biochem Pharmacol. 2007 Apr 01; 73(7):1024-32.Biochem Pharmacol2006-12-15T00:00:002006Curcumin induces the degradation of cyclin E expression through ubiquitin-dependent pathway and up-regulates cyclin-dependent kinase inhibitors p21 and p27 in multiple human tumor cell lines.16604531Li M, Zhai Q, Bharadwaj U, Wang H, Li F, Fisher WE, Chen C, Yao QCancerCyclophilin A is overexpressed in human pancreatic cancer cells and stimulates cell proliferation through CD147. Cancer. 2006 May 15; 106(10):2284-94.Cancer2006-05-15T00:00:002006Cyclophilin A is overexpressed in human pancreatic cancer cells and stimulates cell proliferation through CD147.17532057Yao Q, Doan LX, Zhang R, Bharadwaj U, Li M, Chen CImmunology lettersThymosin-alpha1 modulates dendritic cell differentiation and functional maturation from human peripheral blood CD14+ monocytes. Immunol Lett. 2007 Jun 15; 110(2):110-20.Immunol Lett2007-05-15T00:00:002007Thymosin-alpha1 modulates dendritic cell differentiation and functional maturation from human peripheral blood CD14+ monocytes.17198087Zhang R, Bharadwaj U, Li M, Chen C, Yao QJournal of immunotherapy (Hagerstown, Md. : 1997)Effects of pentoxifylline on differentiation, maturation, and function of human CD14+ monocyte-derived dendritic cells. J Immunother. 2007 Jan; 30(1):89-95.J Immunother2007-01-01T00:00:002007Effects of pentoxifylline on differentiation, maturation, and function of human CD14+ monocyte-derived dendritic cells.18096828Wang X, Liao D, Bharadwaj U, Li M, Yao Q, Chen CArteriosclerosis, thrombosis, and vascular biologyC-reactive protein inhibits cholesterol efflux from human macrophage-derived foam cells. Arterioscler Thromb Vasc Biol. 2008 Mar; 28(3):519-26.Arterioscler Thromb Vasc Biol2007-12-20T00:00:002007C-reactive protein inhibits cholesterol efflux from human macrophage-derived foam cells.17545630Bharadwaj U, Li M, Zhang R, Chen C, Yao QCancer researchElevated interleukin-6 and G-CSF in human pancreatic cancer cell conditioned medium suppress dendritic cell differentiation and activation. Cancer Res. 2007 Jun 01; 67(11):5479-88.Cancer Res2007-06-01T00:00:002007Elevated interleukin-6 and G-CSF in human pancreatic cancer cell conditioned medium suppress dendritic cell differentiation and activation.18281514Li M, Bharadwaj U, Zhang R, Zhang S, Mu H, Fisher WE, Brunicardi FC, Chen C, Yao QMolecular cancer therapeuticsMesothelin is a malignant factor and therapeutic vaccine target for pancreatic cancer. Mol Cancer Ther. 2008 Feb; 7(2):286-96.Mol Cancer Ther2008-02-01T00:00:002008Mesothelin is a malignant factor and therapeutic vaccine target for pancreatic cancer.18658029Chen C, Chai H, Wang X, Jiang J, Jamaluddin MS, Liao D, Zhang Y, Wang H, Bharadwaj U, Zhang S, Li M, Lin P, Yao QBloodSoluble CD40 ligand induces endothelial dysfunction in human and porcine coronary artery endothelial cells. Blood. 2008 Oct 15; 112(8):3205-16.Blood2008-07-24T00:00:002008Soluble CD40 ligand induces endothelial dysfunction in human and porcine coronary artery endothelial cells.19010822Bharadwaj U, Li M, Chen C, Yao QMolecular cancer research : MCRMesothelin-induced pancreatic cancer cell proliferation involves alteration of cyclin E via activation of signal transducer and activator of transcription protein 3. Mol Cancer Res. 2008 Nov; 6(11):1755-65.Mol Cancer Res2008-11-01T00:00:002008Mesothelin-induced pancreatic cancer cell proliferation involves alteration of cyclin E via activation of signal transducer and activator of transcription protein 3.19030926Li M, Marin-Muller C, Bharadwaj U, Chow KH, Yao Q, Chen CWorld journal of surgeryMicroRNAs: control and loss of control in human physiology and disease. World J Surg. 2009 Apr; 33(4):667-84.World J Surg2009-04-01T00:00:002009MicroRNAs: control and loss of control in human physiology and disease.21515913Bharadwaj U, Marin-Muller C, Li M, Chen C, Yao QCarcinogenesisMesothelin overexpression promotes autocrine IL-6/sIL-6R trans-signaling to stimulate pancreatic cancer cell proliferation. Carcinogenesis. 2011 Jul; 32(7):1013-24.Carcinogenesis2011-04-23T00:00:002011Mesothelin overexpression promotes autocrine IL-6/sIL-6R trans-signaling to stimulate pancreatic cancer cell proliferation.21880146Bharadwaj U, Marin-Muller C, Li M, Chen C, Yao QMolecular cancerMesothelin confers pancreatic cancer cell resistance to TNF-a-induced apoptosis through Akt/PI3K/NF-?B activation and IL-6/Mcl-1 overexpression. Mol Cancer. 2011 Aug 31; 10:106.Mol Cancer2011-08-31T00:00:002011Mesothelin confers pancreatic cancer cell resistance to TNF-a-induced apoptosis through Akt/PI3K/NF-?B activation and IL-6/Mcl-1 overexpression.Authorship 841276Authorship 841339Authorship 849105Authorship 852239Authorship 861499Authorship 862493Authorship 863510Authorship 863638Authorship 864425Current ScienceSignificance of human leukocyte antigens in immunobiology of renal transplantation. Current Science. 78:974-988.Significance of human leukocyte antigens in immunobiology of renal transplantationCancersMonoclonal antibodies specific for Stat3β reveal its contribution to constitutive Stat3 phosphorylation in breast cancer. Cancers. 6:2012-2034.Monoclonal antibodies specific for Stat3β reveal its contribution to constitutive Stat3 phosphorylation in breast cancerAllergy: European Journal of Allergy and Clinical ImmunologySTAT3 inhibition prevents lung inflammation, remodeling, and accumulation of Th2 and Th17 cells in a murine asthma model. Allergy: European Journal of Allergy and Clinical Immunology. STAT3 inhibition prevents lung inflammation, remodeling, and accumulation of Th2 and Th17 cells in a murine asthma modelOncogenesisMieap-regulated mitochondrial quality control is frequently inactivated in human colorectal cancer. Oncogenesis. 5:e181.Mieap-regulated mitochondrial quality control is frequently inactivated in human colorectal cancerPLoS OneErratum. PLoS One. 11.ErratumBioMed Research InternationalSubstance P Receptor Signaling Mediates Doxorubicin-Induced Cardiomyocyte Apoptosis and Triple-Negative Breast Cancer Chemoresistance. BioMed Research International. 2016.Substance P Receptor Signaling Mediates Doxorubicin-Induced Cardiomyocyte Apoptosis and Triple-Negative Breast Cancer ChemoresistanceOncotargetSmall-molecule inhibition of STAT3 in radioresistant head and neck squamous cell carcinoma. Oncotarget. 7:26307-26330.Small-molecule inhibition of STAT3 in radioresistant head and neck squamous cell carcinomaLung CancerSmall-molecule targeting of signal transducer and activator of transcription (STAT) 3 to treat non-small cell lung cancer. Lung Cancer. Small-molecule targeting of signal transducer and activator of transcription (STAT) 3 to treat non-small cell lung cancerBiochemical PharmacologyErratum. Biochemical Pharmacology. 102:147.Erratum23572509Elsarraj HS, Hong Y, Valdez K, Carletti M, Salah SM, Raimo M, Taverna D, Prochasson P, Bharadwaj U, Tweardy DJ, Christenson LK, Behbod FJournal of cell scienceA novel role of microRNA146b in promoting mammary alveolar progenitor cell maintenance. J Cell Sci. 2013 Jun 01; 126(Pt 11):2446-58.J Cell Sci2013-04-09T00:00:002013A novel role of microRNA146b in promoting mammary alveolar progenitor cell maintenance.28533225Jung KH, Yoo W, Stevenson HL, Deshpande D, Shen H, Gagea M, Yoo SY, Wang J, Eckols TK, Bharadwaj U, Tweardy DJ, Beretta LClinical cancer research : an official journal of the American Association for Cancer ResearchMultifunctional Effects of a Small-Molecule STAT3 Inhibitor on NASH and Hepatocellular Carcinoma in Mice. Clin Cancer Res. 2017 Sep 15; 23(18):5537-5546.Clin Cancer Res2017-05-22T00:00:002017Multifunctional Effects of a Small-Molecule STAT3 Inhibitor on NASH and Hepatocellular Carcinoma in Mice.12051367Agrawal S, M?ller B, Bharadwaj U, Bhatnagar S, Khan FJournal of forensic sciencesEvaluation of six short tandem repeat loci in forensics: north Indian populations. J Forensic Sci. 2002 May; 47(3):686-9.J Forensic Sci2002-05-01T00:00:002002Evaluation of six short tandem repeat loci in forensics: north Indian populations.20160059Zhang Y, Bharadwaj U, Logsdon CD, Chen C, Yao Q, Li MClinical cancer research : an official journal of the American Association for Cancer ResearchZIP4 regulates pancreatic cancer cell growth by activating IL-6/STAT3 pathway through zinc finger transcription factor CREB. Clin Cancer Res. 2010 Mar 01; 16(5):1423-30.Clin Cancer Res2010-02-16T00:00:002010ZIP4 regulates pancreatic cancer cell growth by activating IL-6/STAT3 pathway through zinc finger transcription factor CREB.20667573Lay MK, Atmar RL, Guix S, Bharadwaj U, He H, Neill FH, Sastry KJ, Yao Q, Estes MKVirologyNorwalk virus does not replicate in human macrophages or dendritic cells derived from the peripheral blood of susceptible humans. Virology. 2010 Oct 10; 406(1):1-11.Virology2010-07-29T00:00:002010Norwalk virus does not replicate in human macrophages or dendritic cells derived from the peripheral blood of susceptible humans.29129918Singh M, Vianden C, Cantwell MJ, Dai Z, Xiao Z, Sharma M, Khong H, Jaiswal AR, Faak F, Hailemichael Y, Janssen LME, Bharadwaj U, Curran MA, Diab A, Bassett RL, Tweardy DJ, Hwu P, Overwijk WWNature communicationsIntratumoral CD40 activation and checkpoint blockade induces T cell-mediated eradication of melanoma in the brain. Nat Commun. 2017 11 13; 8(1):1447.Nat Commun2017-11-13T00:00:002017Intratumoral CD40 activation and checkpoint blockade induces T cell-mediated eradication of melanoma in the brain.true1ProfessorProfessorAuthorship 8868081Authorship 8874103Authorship 8878501Authorship 88805310Authorship 8882412Authorship 88978012D009284Chemicals & Drugs17250.958828NaphtholsD050796Chemicals & Drugs38311200.601299STAT3 Transcription FactorD015850Chemicals & Drugs51210360.694649Interleukin-6Surgery-Surgical ResearchAuthorship 9288636Authorship 932759229149493Economides MP, Amit M, Mahale PS, Hosry JJ, Jiang Y, Bharadwaj U, Sturgis EM, Torres HACancerImpact of chronic hepatitis C virus infection on the survival of patients with oropharyngeal cancer. Cancer. 2018 03 01; 124(5):960-965.Cancer2017-11-17T00:00:002017Impact of chronic hepatitis C virus infection on the survival of patients with oropharyngeal cancer.30081609Kasembeli MM, Bharadwaj U, Robinson P, Tweardy DJInternational journal of molecular sciencesContribution of STAT3 to Inflammatory and Fibrotic Diseases and Prospects for its Targeting for Treatment. Int J Mol Sci. 2018 Aug 05; 19(8).Int J Mol Sci2018-08-05T00:00:002018Contribution of STAT3 to Inflammatory and Fibrotic Diseases and Prospects for its Targeting for Treatment.D053612Chemicals & Drugs871740.879594Janus KinasesPathologyDepartment of SurgeryBaylor College of MedicineQIZHIYAOQIZHI YAO29.71073630000000-95.39660450000000423YAO, QIZHIProfessorCHANGYICHENCHANGYI CHEN29.71073630000000-95.39660450000000426CHEN, CHANGYIProfessorAuthorship 943324130899429Bharadwaj U, Eckols TK, Xu X, Kasembeli MM, Chen Y, Adachi M, Song Y, Mo Q, Lai SY, Tweardy DJOncotargetCorrection: Small-molecule inhibition of STAT3 in radioresistant head and neck squamous cell carcinoma. Oncotarget. 2019 02 22; 10(16):1603.Oncotarget2019-02-22T00:00:002019Correction: Small-molecule inhibition of STAT3 in radioresistant head and neck squamous cell carcinoma.D058851Chemicals & Drugs1422230.922423GPI-Linked ProteinsAuthorship 9768551532005826Sharma M, Khong H, Fa'ak F, Bentebibel SE, Janssen LME, Chesson BC, Creasy CA, Forget MA, Kahn LMS, Pazdrak B, Karki B, Hailemichael Y, Singh M, Vianden C, Vennam S, Bharadwaj U, Tweardy DJ, Haymaker C, Bernatchez C, Huang S, Rajapakshe K, Coarfa C, Hurwitz ME, Sznol M, Hwu P, Hoch U, Addepalli M, Charych DH, Zalevsky J, Diab A, Overwijk WWNature communicationsBempegaldesleukin selectively depletes intratumoral Tregs and potentiates T cell-mediated cancer therapy. Nat Commun. 2020 01 31; 11(1):661.Nat Commun2020-01-31T00:00:002020Bempegaldesleukin selectively depletes intratumoral Tregs and potentiates T cell-mediated cancer therapy.Authorship 979539132198236Bharadwaj U, Kasembeli MM, Robinson P, Tweardy DJPharmacological reviewsTargeting Janus Kinases and Signal Transducer and Activator of Transcription 3 to Treat Inflammation, Fibrosis, and Cancer: Rationale, Progress, and Caution. Pharmacol Rev. 2020 04; 72(2):486-526.Pharmacol Rev2020-04-01T00:00:002020Targeting Janus Kinases and Signal Transducer and Activator of Transcription 3 to Treat Inflammation, Fibrosis, and Cancer: Rationale, Progress, and Caution.Authorship 1017473233932608Kong R, Bharadwaj U, Eckols TK, Kolosov M, Wu H, Cruz-Pavlovich FJS, Shaw A, Ifelayo OI, Zhao H, Kasembeli MM, Wong STC, Tweardy DJPharmacological researchNovel STAT3 small-molecule inhibitors identified by structure-based virtual ligand screening incorporating SH2 domain flexibility. Pharmacol Res. 2021 07; 169:105637.Pharmacol Res2021-04-29T00:00:002021Novel STAT3 small-molecule inhibitors identified by structure-based virtual ligand screening incorporating SH2 domain flexibility.Authorship 1041522335251033Wurster S, Albert ND, Bharadwaj U, Kasembeli MM, Tarrand JJ, Daver N, Kontoyiannis DPFrontiers in immunologyBlockade of the PD-1/PD-L1 Immune Checkpoint Pathway Improves Infection Outcomes and Enhances Fungicidal Host Defense in a Murine Model of Invasive Pulmonary Mucormycosis. Front Immunol. 2022; 13:838344.Front Immunol2022-02-18T00:00:002022Blockade of the PD-1/PD-L1 Immune Checkpoint Pathway Improves Infection Outcomes and Enhances Fungicidal Host Defense in a Murine Model of Invasive Pulmonary Mucormycosis.23989979Marin-Muller C, Li D, Bharadwaj U, Li M, Chen C, Hodges SE, Fisher WE, Mo Q, Hung MC, Yao QClinical cancer research : an official journal of the American Association for Cancer ResearchA tumorigenic factor interactome connected through tumor suppressor microRNA-198 in human pancreatic cancer. Clin Cancer Res. 2013 Nov 01; 19(21):5901-13.Clin Cancer Res2013-08-29T00:00:002013A tumorigenic factor interactome connected through tumor suppressor microRNA-198 in human pancreatic cancer.Authorship 1059128336240433Kasembeli MM, Kaparos E, Bharadwaj U, Allaw A, Khouri A, Acot B, Tweardy DJBloodAberrant function of pathogenic STAT3 mutant proteins is linked to altered stability of monomers and homodimers. Blood. 2023 03 23; 141(12):1411-1424.Blood2023-03-23T00:00:002023Aberrant function of pathogenic STAT3 mutant proteins is linked to altered stability of monomers and homodimers.Authorship 1073184837296943Robinson P, Montoya K, Magness E, Rodriguez E, Villalobos V, Engineer N, Yang P, Bharadwaj U, Eckols TK, Tweardy DJCancersTherapeutic Potential of a Small-Molecule STAT3 Inhibitor in a Mouse Model of Colitis. Cancers (Basel). 2023 May 30; 15(11).Cancers (Basel)2023-05-30T00:00:002023Therapeutic Potential of a Small-Molecule STAT3 Inhibitor in a Mouse Model of Colitis.true1ProfessorProfessorAuthorship 1089628838415653Kumaresan PR, Wurster S, Bavisi K, da Silva TA, Hauser P, Kinnitt J, Albert ND, Bharadwaj U, Neelapu S, Kontoyiannis DPmBioA novel lentiviral vector-based approach to generate chimeric antigen receptor T cells targeting Aspergillus fumigatus. mBio. 2024 Feb 28; e0341323.mBio2024-02-28T00:00:002024A novel lentiviral vector-based approach to generate chimeric antigen receptor T cells targeting Aspergillus fumigatus.true1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1Assistant ProfessorAssistant Professortrue1Assistant ProfessorAssistant Professortrue1Associate ProfessorAssociate Professortrue1ProfessorProfessor24912006Prakash S, Alam S, Bharadwaj U, Aggarwal A, Mishra RN, Agrawal SHuman immunologyAssociations of killer cell immunoglobulin like receptors with rheumatoid arthritis among North Indian population. Hum Immunol. 2014 Aug; 75(8):802-7.Hum Immunol2014-06-06T00:00:002014Associations of killer cell immunoglobulin like receptors with rheumatoid arthritis among North Indian population.25268166Bharadwaj U, Kasembeli MM, Eckols TK, Kolosov M, Lang P, Christensen K, Edwards DP, Tweardy DJCancersMonoclonal Antibodies Specific for STAT3? Reveal Its Contribution to Constitutive STAT3 Phosphorylation in Breast Cancer. Cancers (Basel). 2014 Sep 29; 6(4):2012-34.Cancers (Basel)2014-09-29T00:00:002014Monoclonal Antibodies Specific for STAT3? Reveal Its Contribution to Constitutive STAT3 Phosphorylation in Breast Cancer.