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PHILIPP MAXIMOV

TitleAssistant Professor
InstitutionMD Anderson
DepartmentBreast Medical Oncology
Address1901 East Road
Houston TX 77054-3005
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Maximov PY, Fan P, Abderrahman B, Curpan R, Jordan VC. Estrogen Receptor Complex to Trigger or Delay Estrogen-Induced Apoptosis in Long-Term Estrogen Deprived Breast Cancer. Front Endocrinol (Lausanne). 2022; 13:869562. PMID: 35360069; PMCID: PMC8960923.
      Citations:    Fields:    Translation:Humans
    2. Abderrahman B, Maximov PY, Curpan RF, Fanning SW, Hanspal JS, Fan P, Foulds CE, Chen Y, Malovannaya A, Jain A, Xiong R, Greene GL, Tonetti DA, Thatcher GRJ, Jordan VC. Rapid Induction of the Unfolded Protein Response and Apoptosis by Estrogen Mimic TTC-352 for the Treatment of Endocrine-Resistant Breast Cancer. Mol Cancer Ther. 2021 01; 20(1):11-25. PMID: 33177154; PMCID: PMC7790886.
      Citations: 5     Fields:    Translation:HumansCells
    3. Volpato M, Cummings M, Shaaban AM, Abderrahman B, Hull MA, Maximov PY, Broom BM, Fan P, Jordan VC, Speirs V, Hoppe R, Brauch H. Downregulation of 15-hydroxyprostaglandin dehydrogenase during acquired tamoxifen resistance and association with poor prognosis in ERa-positive breast cancer. Explor Target Antitumor Ther. 2020; 1:355-371. PMID: 33210098; PMCID: PMC7116369.
      Citations: 3     
    4. Abderrahman B, Maximov PY, Curpan RF, Hanspal JS, Fan P, Xiong R, Tonetti DA, Thatcher GRJ, Jordan VC. Pharmacology and Molecular Mechanisms of Clinically Relevant Estrogen Estetrol and Estrogen Mimic BMI-135 for the Treatment of Endocrine-Resistant Breast Cancer. Mol Pharmacol. 2020 10; 98(4):364-381. PMID: 32788222; PMCID: PMC7491312.
      Citations: 7     Fields:    Translation:HumansCells
    5. Maximov PY, Abderrahman B, Hawsawi YM, Chen Y, Foulds CE, Jain A, Malovannaya A, Fan P, Curpan RF, Han R, Fanning SW, Broom BM, Quintana Rincon DM, Greenland JA, Greene GL, Jordan VC. The Structure-Function Relationship of Angular Estrogens and Estrogen Receptor Alpha to Initiate Estrogen-Induced Apoptosis in Breast Cancer Cells. Mol Pharmacol. 2020 07; 98(1):24-37. PMID: 32362585; PMCID: PMC7294906.
      Citations: 9     Fields:    Translation:HumansCells
    6. Maximov PY, Abderrahman B, Fanning SW, Sengupta S, Fan P, Curpan RF, Rincon DMQ, Greenland JA, Rajan SS, Greene GL, Jordan VC. Endoxifen, 4-Hydroxytamoxifen and an Estrogenic Derivative Modulate Estrogen Receptor Complex Mediated Apoptosis in Breast Cancer. Mol Pharmacol. 2018 08; 94(2):812-822. PMID: 29739819; PMCID: PMC6022805.
      Citations: 4     Fields:    Translation:HumansCells
    7. Maximov PY, Abderrahman B, Curpan RF, Hawsawi YM, Fan P, Jordan VC. A unifying biology of sex steroid-induced apoptosis in prostate and breast cancers. Endocr Relat Cancer. 2018 02; 25(2):R83-R113. PMID: 29162647; PMCID: PMC5771961.
      Citations: 11     Fields:    Translation:HumansAnimals
    8. Jordan VC, Fan P, Abderrahman B, Maximov PY, Hawsawi YM, Bhattacharya P, Pokharel N. Sex steroid induced apoptosis as a rational strategy to treat anti-hormone resistant breast and prostate cancer. Discov Med. 2016 05; 21(117):411-27. PMID: 27355337.
      Citations: 11     Fields:    Translation:Humans
    9. Jordan VC, Maximov PY, Fan P. Progesterone and Synthetic Progestin Controversies. JAMA Oncol. 2015 Oct; 1(7):986-7. PMID: 26448286.
      Citations: 1     Fields:    Translation:Humans
    10. Fan P, Cunliffe HE, Maximov PY, Agboke FA, McDaniel RE, Zou X, Ramos P, Russell ML, Jordan VC. Integration of Downstream Signals of Insulin-like Growth Factor-1 Receptor by Endoplasmic Reticulum Stress for Estrogen-Induced Growth or Apoptosis in Breast Cancer Cells. Mol Cancer Res. 2015 Oct; 13(10):1367-76. PMID: 26116171; PMCID: PMC4763612.
      Citations: 19     Fields:    Translation:HumansCells
    11. Fan P, Maximov PY, Curpan RF, Abderrahman B, Jordan VC. The molecular, cellular and clinical consequences of targeting the estrogen receptor following estrogen deprivation therapy. Mol Cell Endocrinol. 2015 Dec 15; 418 Pt 3:245-63. PMID: 26052034; PMCID: PMC4760743.
      Citations: 16     Fields:    Translation:Humans
    12. Jordan VC, Curpan R, Maximov PY. Estrogen receptor mutations found in breast cancer metastases integrated with the molecular pharmacology of selective ER modulators. J Natl Cancer Inst. 2015 Jun; 107(6):djv075. PMID: 25838462; PMCID: PMC6390275.
      Citations: 16     Fields:    Translation:Humans
    13. Maximov PY, McDaniel RE, Fernandes DJ, Korostyshevskiy VR, Bhatta P, Flockhart DA, Jordan VC, M?rdter TE. Simulation with cells in vitro of tamoxifen treatment in premenopausal breast cancer patients with different CYP2D6 genotypes. Br J Pharmacol. 2014 Dec; 171(24):5624-35. PMID: 25073551; PMCID: PMC4290706.
      Citations: 17     Fields:    Translation:HumansCells
    14. Maximov PY, McDaniel RE, Fernandes DJ, Bhatta P, Korostyshevskiy VR, Curpan RF, Jordan VC. Pharmacological relevance of endoxifen in a laboratory simulation of breast cancer in postmenopausal patients. J Natl Cancer Inst. 2014 Oct; 106(10). PMID: 25258390; PMCID: PMC4271116.
      Citations: 11     Fields:    Translation:HumansCells
    15. Molloy ME, White BE, Gherezghiher T, Michalsen BT, Xiong R, Patel H, Zhao H, Maximov PY, Jordan VC, Thatcher GR, Tonetti DA. Novel selective estrogen mimics for the treatment of tamoxifen-resistant breast cancer. Mol Cancer Ther. 2014 Nov; 13(11):2515-26. PMID: 25205655; PMCID: PMC4221411.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    16. Craig Jordan V, McDaniel R, Agboke F, Maximov PY. The evolution of nonsteroidal antiestrogens to become selective estrogen receptor modulators. Steroids. 2014 Nov; 90:3-12. PMID: 24949934; PMCID: PMC4192084.
      Citations: 4     Fields:    Translation:HumansAnimals
    17. Maximov PY, Fernandes DJ, McDaniel RE, Myers CB, Curpan RF, Jordan VC. Influence of the length and positioning of the antiestrogenic side chain of endoxifen and 4-hydroxytamoxifen on gene activation and growth of estrogen receptor positive cancer cells. J Med Chem. 2014 Jun 12; 57(11):4569-83. PMID: 24805199; PMCID: PMC4059272.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    18. Maximov PY, Lee TM, Jordan VC. The discovery and development of selective estrogen receptor modulators (SERMs) for clinical practice. Curr Clin Pharmacol. 2013 May; 8(2):135-55. PMID: 23062036; PMCID: PMC3624793.
      Citations: 98     Fields:    Translation:HumansAnimals
    19. McDaniel RE, Maximov PY, Jordan VC. Estrogen-mediated mechanisms to control the growth and apoptosis of breast cancer cells: a translational research success story. Vitam Horm. 2013; 93:1-49. PMID: 23810002.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    20. Sweeney EE, McDaniel RE, Maximov PY, Fan P, Jordan VC. Models and Mechanisms of Acquired Antihormone Resistance in Breast Cancer: Significant Clinical Progress Despite Limitations. Horm Mol Biol Clin Investig. 2012 Feb; 9(2):143-163. PMID: 23308083; PMCID: PMC3539798.
      Citations: 30     Fields:    
    21. Maximov P, Sengupta S, Lewis-Wambi JS, Kim HR, Curpan RF, Jordan VC. The Conformation of the Estrogen Receptor Directs Estrogen-Induced Apoptosis in Breast Cancer: A Hypothesis. Horm Mol Biol Clin Investig. 2011 Mar 01; 5(1):27-34. PMID: 21660224; PMCID: PMC3109984.
      Citations: 12     Fields:    
    22. Maximov PY, Myers CB, Curpan RF, Lewis-Wambi JS, Jordan VC. Structure-function relationships of estrogenic triphenylethylenes related to endoxifen and 4-hydroxytamoxifen. J Med Chem. 2010 Apr 22; 53(8):3273-83. PMID: 20334368; PMCID: PMC2867604.
      Citations: 24     Fields:    Translation:HumansCells
    23. Maximov PY, Lewis-Wambi JS, Jordan VC. The Paradox of Oestradiol-Induced Breast Cancer Cell Growth and Apoptosis. Curr Signal Transduct Ther. 2009 May 01; 4(2):88-102. PMID: 19809537; PMCID: PMC2757321.
      Citations: 12     
    24. The paradox of oestradiol-induced breast cancer cell growth and apoptosis. Current Signal Transduction Therapy. 4:88-102.
    25. Is there a role for raloxifene and tamoxifen for the prevention of breast cancer?. 83-101.
    26. Sex steroid induced apoptosis as a rational strategy to treat anti-hormone resistant breast and prostate cancer. Discovery medicine. 21:321-337.
    27. Integration of downstream signals of insulin-like growth factor-1 receptor by endoplasmic reticulum stress for estrogen-induced growth or apoptosis in breast cancer cells. Molecular Cancer Research. 13:1367-1376.
    28. The molecular, cellular and clinical consequences of targeting the estrogen receptor following estrogen deprivation therapy. Molecular and Cellular Endocrinology.
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