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SHAVALI SHAIK

TitleInstructor
InstitutionMD Anderson
DepartmentPediatrics
Address1515 Holcombe Blvd.
Houston TX 77030
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Swaminathan J, Maegawa S, Shaik S, Sharma A, Bravo-Alegria J, Guo L, Xu L, Harmanci A, Gopalakrishnan V. Cross-Talk Between Histone Methyltransferases and Demethylases Regulate REST Transcription During Neurogenesis. Front Oncol. 2022; 12:855167. PMID: 35600406; PMCID: PMC9120943.
      Citations:    
    2. Shaik S, Maegawa S, Gopalakrishnan V. Medulloblastoma: novel insights into emerging therapeutic targets. Expert Opin Ther Targets. 2021 08; 25(8):615-619. PMID: 34602009; PMCID: PMC8552961.
      Citations:    Fields:    Translation:Humans
    3. Shaik S, Maegawa S, Haltom AR, Wang F, Xiao X, Dobson T, Sharma A, Yang Y, Swaminathan J, Kundra V, Li XN, Schadler K, Harmanci A, Xu L, Gopalakrishnan V. REST promotes ETS1-dependent vascular growth in medulloblastoma. Mol Oncol. 2021 05; 15(5):1486-1506. PMID: 33469989; PMCID: PMC8096796.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    4. Dobson THW, Tao RH, Swaminathan J, Maegawa S, Shaik S, Bravo-Alegria J, Sharma A, Kennis B, Yang Y, Callegari K, Haltom AR, Taylor P, Kogiso M, Qi L, Khatua S, Goldman S, Lulla RR, Fangusaro J, MacDonald TJ, Li XN, Hawkins C, Rajaram V, Gopalakrishnan V. Transcriptional repressor REST drives lineage stage-specific chromatin compaction at Ptch1 and increases AKT activation in a mouse model of medulloblastoma. Sci Signal. 2019 01 22; 12(565). PMID: 30670636; PMCID: PMC8939892.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    5. Shaik S, Kennis B, Maegawa S, Schadler K, Yanwen Y, Callegari K, Lulla RR, Goldman S, Nazarian J, Rajaram V, Fangusaro J, Gopalakrishnan V. REST upregulates gremlin to modulate diffuse intrinsic pontine glioma vasculature. Oncotarget. 2018 Jan 12; 9(4):5233-5250. PMID: 29435175; PMCID: PMC5797046.
      Citations: 7     Fields:    
    6. Dobson THW, Hatcher RJ, Swaminathan J, Das CM, Shaik S, Tao RH, Taylor PH, Gopalakrishnan V, Milite C, Castellano S, Sbardella G. Regulation of USP37 Expression by REST-Associated G9a-Dependent Histone Methylation. Mol Cancer Res. 2017 08; 15(8):1073-1084. PMID: 28483947; PMCID: PMC5540785.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    7. Li N, Fassl A, Chick J, Inuzuka H, Li X, Mansour MR, Liu L, Wang H, King B, Shaik S, Gutierrez A, Ordureau A, Otto T, Kreslavsky T, Baitsch L, Bury L, Meyer CA, Ke N, Mulry KA, Kluk MJ, Roy M, Kim S, Zhang X, Geng Y, Zagozdzon A, Jenkinson S, Gale RE, Linch DC, Zhao JJ, Mullighan CG, Harper JW, Aster JC, Aifantis I, von Boehmer H, Gygi SP, Wei W, Look AT, Sicinski P. Cyclin C is a haploinsufficient tumour suppressor. Nat Cell Biol. 2014 Nov; 16(11):1080-91. PMID: 25344755; PMCID: PMC4235773.
      Citations: 56     Fields:    Translation:HumansAnimalsCells
    8. Zhong J, Shaik S, Wan L, Tron AE, Wang Z, Sun L, Inuzuka H, Wei W. SCF ?-TRCP targets MTSS1 for ubiquitination-mediated destruction to regulate cancer cell proliferation and migration. Oncotarget. 2013 Dec; 4(12):2339-53. PMID: 24318128; PMCID: PMC3926831.
      Citations: 32     Fields:    Translation:HumansCells
    9. Shaik S, Nucera C, Inuzuka H, Gao D, Garnaas M, Frechette G, Harris L, Wan L, Fukushima H, Husain A, Nose V, Fadda G, Sadow PM, Goessling W, North T, Lawler J, Wei W. SCF(?-TRCP) suppresses angiogenesis and thyroid cancer cell migration by promoting ubiquitination and destruction of VEGF receptor 2. J Exp Med. 2012 Jul 02; 209(7):1289-307. PMID: 22711876; PMCID: PMC3405505.
      Citations: 45     Fields:    Translation:HumansAnimalsCells
    10. Fukushima H, Matsumoto A, Inuzuka H, Zhai B, Lau AW, Wan L, Gao D, Shaik S, Yuan M, Gygi SP, Jimi E, Asara JM, Nakayama K, Nakayama KI, Wei W. SCF(Fbw7) modulates the NFkB signaling pathway by targeting NFkB2 for ubiquitination and destruction. Cell Rep. 2012 May 31; 1(5):434-43. PMID: 22708077; PMCID: PMC3375724.
      Citations: 46     Fields:    Translation:HumansAnimalsCells
    11. Inuzuka H, Fukushima H, Shaik S, Liu P, Lau AW, Wei W. Mcl-1 ubiquitination and destruction. Oncotarget. 2011 Mar; 2(3):239-44. PMID: 21608150; PMCID: PMC3260810.
      Citations: 45     Fields:    Translation:HumansCells
    12. Inuzuka H, Fukushima H, Shaik S, Wei W, Inuzuka H. Novel insights into the molecular mechanisms governing Mdm2 ubiquitination and destruction. Oncotarget. 2010 Nov; 1(7):685-690. PMID: 21317463; PMCID: PMC3248122.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    13. Systems biology approaches in breast cancer studies. 329-340.
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