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HIROKI TORIKAI

TitleInstructor
InstitutionMD Anderson
DepartmentPediatrics
Address1515 Holcombe Blvd.
Houston TX 77030
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Zong S, Mi T, Flores LG, Alpert A, Olivares S, Patel K, Maiti S, Mcnamara G, Cooper LJN, Torikai H. Very rapid cloning, expression and identifying specificity of T-cell receptors for T-cell engineering. PLoS One. 2020; 15(2):e0228112. PMID: 32040512; PMCID: PMC7010234.
      Citations: 3     Fields:    Translation:HumansCells
    2. Weng J, Baio FE, Moriarty KE, Torikai H, Wang H, Liu Z, Maiti SN, Gwak D, Popescu MS, Cha SC, Cooper LJ, Neelapu SS, Kwak LW. Targeting B-cell malignancies through human B-cell receptor specific CD4+ T cells. Oncoimmunology. 2016; 5(11):e1232220. PMID: 27999743; PMCID: PMC5139634.
      Citations: 2     Fields:    
    3. Thokala R, Olivares S, Mi T, Maiti S, Deniger D, Huls H, Torikai H, Singh H, Champlin RE, Laskowski T, McNamara G, Cooper LJ. Redirecting Specificity of T cells Using the Sleeping Beauty System to Express Chimeric Antigen Receptors by Mix-and-Matching of VL and VH Domains Targeting CD123+ Tumors. PLoS One. 2016; 11(8):e0159477. PMID: 27548616; PMCID: PMC4993583.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    4. Torikai H, Zhang L, Maiti S, Dai J, Do KA, Singh H, Huls H, Lee DA, Champlin RE, Heimberger AB, Cooper LJ, Caruso HG. Redirecting T-Cell Specificity to EGFR Using mRNA to Self-limit Expression of Chimeric Antigen Receptor. J Immunother. 2016 06; 39(5):205-17. PMID: 27163741; PMCID: PMC5847343.
      Citations: 17     Fields:    Translation:HumansCells
    5. Tian G, Courtney AN, Jena B, Heczey A, Liu D, Marinova E, Guo L, Xu X, Torikai H, Mo Q, Dotti G, Cooper LJ, Metelitsa LS. CD62L+ NKT cells have prolonged persistence and antitumor activity in vivo. J Clin Invest. 2016 06 01; 126(6):2341-55. PMID: 27183388; PMCID: PMC4887157.
      Citations: 64     Fields:    Translation:HumansAnimalsCells
    6. Torikai H, Cooper LJ. Translational Implications for Off-the-shelf Immune Cells Expressing Chimeric Antigen Receptors. Mol Ther. 2016 08; 24(7):1178-86. PMID: 27203439; PMCID: PMC5088751.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    7. Torikai H, Mi T, Gragert L, Maiers M, Najjar A, Ang S, Maiti S, Dai J, Switzer KC, Huls H, Dulay GP, Reik A, Rebar EJ, Holmes MC, Gregory PD, Champlin RE, Shpall EJ, Cooper LJ. Genetic editing of HLA expression in hematopoietic stem cells to broaden their human application. Sci Rep. 2016 Feb 23; 6:21757. PMID: 26902653; PMCID: PMC4763194.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    8. Torikai H, Reik A, Soldner F, Warren EH, Yuen C, Zhou Y, Crossland DL, Huls H, Littman N, Zhang Z, Tykodi SS, Kebriaei P, Lee DA, Miller JC, Rebar EJ, Holmes MC, Jaenisch R, Champlin RE, Gregory PD, Cooper LJ. Toward eliminating HLA class I expression to generate universal cells from allogeneic donors. Blood. 2013 Aug 22; 122(8):1341-9. PMID: 23741009; PMCID: PMC3750336.
      Citations: 124     Fields:    Translation:HumansCells
    9. Maiti SN, Huls H, Singh H, Dawson M, Figliola M, Olivares S, Rao P, Zhao YJ, Multani A, Yang G, Zhang L, Crossland D, Ang S, Torikai H, Rabinovich B, Lee DA, Kebriaei P, Hackett P, Champlin RE, Cooper LJ. Sleeping beauty system to redirect T-cell specificity for human applications. J Immunother. 2013 Feb; 36(2):112-23. PMID: 23377665; PMCID: PMC3568214.
      Citations: 41     Fields:    Translation:HumansAnimalsCells
    10. Demachi-Okamura A, Torikai H, Akatsuka Y, Miyoshi H, Yoshimori T, Kuzushima K. Autophagy creates a CTL epitope that mimics tumor-associated antigens. PLoS One. 2012; 7(10):e47126. PMID: 23071732; PMCID: PMC3469533.
      Citations: 5     Fields:    Translation:HumansCells
    11. Torikai H, Reik A, Liu PQ, Zhou Y, Zhang L, Maiti S, Huls H, Miller JC, Kebriaei P, Rabinovich B, Rabinovitch B, Lee DA, Champlin RE, Bonini C, Naldini L, Rebar EJ, Gregory PD, Holmes MC, Cooper LJ. A foundation for universal T-cell based immunotherapy: T cells engineered to express a CD19-specific chimeric-antigen-receptor and eliminate expression of endogenous TCR. Blood. 2012 Jun 14; 119(24):5697-705. PMID: 22535661; PMCID: PMC3382929.
      Citations: 212     Fields:    Translation:HumansCells
    12. Hirosawa T, Torikai H, Yanagisawa M, Kamei M, Imahashi N, Demachi-Okamura A, Tanimoto M, Shiraishi K, Ito M, Miyamura K, Shibata K, Kikkawa F, Morishima Y, Takahashi T, Emi N, Kuzushima K, Akatsuka Y. Mismatched human leukocyte antigen class II-restricted CD8? cytotoxic T cells may mediate selective graft-versus-leukemia effects following allogeneic hematopoietic cell transplantation. Cancer Sci. 2011 Jul; 102(7):1281-6. PMID: 21466613.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    13. Choi Y, Yuen C, Maiti SN, Olivares S, Gibbons H, Huls H, Raphael R, Killian TC, Stark DJ, Lee DA, Torikai H, Monticello D, Kelly SS, Kebriaei P, Champlin RE, Biswal SL, Cooper LJ. A high throughput microelectroporation device to introduce a chimeric antigen receptor to redirect the specificity of human T cells. Biomed Microdevices. 2010 Oct; 12(5):855-63. PMID: 20574820; PMCID: PMC4109048.
      Citations: 11     Fields:    Translation:HumansCells
    14. Kamei M, Nannya Y, Torikai H, Kawase T, Taura K, Inamoto Y, Takahashi T, Yazaki M, Morishima S, Tsujimura K, Miyamura K, Ito T, Togari H, Riddell SR, Kodera Y, Morishima Y, Takahashi T, Kuzushima K, Ogawa S, Akatsuka Y. HapMap scanning of novel human minor histocompatibility antigens. Blood. 2009 May 21; 113(21):5041-8. PMID: 18809759; PMCID: PMC3654783.
      Citations: 26     Fields:    Translation:HumansCells
    15. Torikai H, Akatsuka Y, Yatabe Y, Morishima Y, Kodera Y, Kuzushima K, Takahashi T. Aberrant expression of BCL2A1-restricted minor histocompatibility antigens in melanoma cells: application for allogeneic transplantation. Int J Hematol. 2008 Jun; 87(5):467-473. PMID: 18414982.
      Citations: 7     Fields:    Translation:HumansCells
    16. Kobayashi S, Sato K, Torikai H, Ogura K, Kobayashi A, Bamba Y, Ikeda T, Kimura F, Motoyoshi K. Transformation of myelodysplastic syndrome into myeloid/natural killer cell precursor acute leukemia involving mainly lymph nodes. Leuk Lymphoma. 2008 Feb; 49(2):342-5. PMID: 18231923.
      Citations: 1     Fields:    Translation:HumansCells
    17. Kawase T, Nannya Y, Torikai H, Yamamoto G, Onizuka M, Morishima S, Tsujimura K, Miyamura K, Kodera Y, Morishima Y, Takahashi T, Kuzushima K, Ogawa S, Akatsuka Y. Identification of human minor histocompatibility antigens based on genetic association with highly parallel genotyping of pooled DNA. Blood. 2008 Mar 15; 111(6):3286-94. PMID: 18178869.
      Citations: 24     Fields:    Translation:HumansCells
    18. Kobayashi S, Kimura F, Ogura K, Kobayashi A, Torikai H, Ikeda T, Sato K, Saionji K, Ito T, Saito D, Motoyoshi K. [Methicillin-resistant Staphylococcus aureus-induced pyomyositis that emerged during recovery from drug-induced pancytopenia]. Rinsho Ketsueki. 2008 Jan; 49(1):55-8. PMID: 18277598.
      Citations:    Fields:    Translation:HumansCells
    19. Kobayashi S, Kimura F, Hama Y, Ogura K, Torikai H, Kobayashi A, Ikeda T, Sato K, Aida S, Kosuda S, Motoyoshi K. Histiocytic sarcoma of the spleen: case report of asymptomatic onset of thrombocytopenia and complex imaging features. Int J Hematol. 2008 Jan; 87(1):83-7. PMID: 18224419.
      Citations: 10     Fields:    Translation:Humans
    20. Kawase T, Akatsuka Y, Torikai H, Morishima S, Oka A, Tsujimura A, Miyazaki M, Tsujimura K, Miyamura K, Ogawa S, Inoko H, Morishima Y, Kodera Y, Kuzushima K, Takahashi T. Alternative splicing due to an intronic SNP in HMSD generates a novel minor histocompatibility antigen. Blood. 2007 Aug 01; 110(3):1055-63. PMID: 17409267.
      Citations: 37     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    21. Morishima S, Akatsuka Y, Nawa A, Kondo E, Kiyono T, Torikai H, Nakanishi T, Ito Y, Tsujimura K, Iwata K, Ito K, Kodera Y, Morishima Y, Kuzushima K, Takahashi T. Identification of an HLA-A24-restricted cytotoxic T lymphocyte epitope from human papillomavirus type-16 E6: the combined effects of bortezomib and interferon-gamma on the presentation of a cryptic epitope. Int J Cancer. 2007 Feb 01; 120(3):594-604. PMID: 17096336.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    22. Akatsuka Y, Torikai H, Inamoto Y, Tsujimura K, Morishima Y, Kodera Y, Kuzushima K, Takahashi T. Bone marrow may be a reservoir of long-lived memory T cells specific for minor histocompatibility antigen. Br J Haematol. 2006 Nov; 135(3):413-4. PMID: 16978218.
      Citations: 3     Fields:    Translation:HumansCells
    23. Watanabe J, Ogura K, Kobayashi S, Torikai H, Ikeda T, Sato K, Kimura F, Motoyoshi K. [HHV-6 encephalitis after unrelated cord blood transplantation in a patient with acute lymphoblastic leukemia]. Nihon Naika Gakkai Zasshi. 2005 Nov 10; 94(11):2388-90. PMID: 16363745.
      Citations:    Fields:    Translation:HumansCells
    24. Ogura K, Kimura F, Kobayashi S, Torikai H, Ikeda T, Sato K, Motoyoshi K. Myeloid/NK cell precursor acute leukemia lost both CD13 and CD33 at first diagnosis. Leuk Res. 2006 Jun; 30(6):761-3. PMID: 16140376.
      Citations: 2     Fields:    Translation:HumansCells
    25. Torikai H, Akatsuka Y, Miyazaki M, Warren EH, Oba T, Tsujimura K, Motoyoshi K, Morishima Y, Kodera Y, Kuzushima K, Takahashi T. A novel HLA-A*3303-restricted minor histocompatibility antigen encoded by an unconventional open reading frame of human TMSB4Y gene. J Immunol. 2004 Dec 01; 173(11):7046-54. PMID: 15557202.
      Citations: 14     Fields:    Translation:HumansCells
    26. Kimura F, Kobayashi S, Ogura K, Kobayashi A, Torikai H, Ikeda T, Sato K, Motoyoshi K. [Emergence and decrement of Ph-negative clone with trisomy 8 in CML during imatinib therapy]. Rinsho Ketsueki. 2004 Sep; 45(9):1058-60. PMID: 15510836.
      Citations:    Fields:    Translation:HumansCells
    27. CD62L+ NKT cells have prolonged persistence and antitumor activity in vivo. Journal of Clinical Investigation. 126:2341-2355.
    28. Targeting B-cell malignancies through human B-cell receptor specific CD4+ T cells. OncoImmunology. 5.
    29. Redirecting T-cell specificity to EGFR using mRNA to self-limit expression of chimeric antigen receptor. Journal of Immunotherapy. 39:205-217.
    30. Redirecting specificity of t cells using the Sleeping Beauty system to express chimeric antigen receptors by mix-and-matching of VL and VH domains targeting CD123+ tumors. PLoS One. 11.
    31. Genetic editing of HLA expression in hematopoietic stem cells to broaden their human application. Scientific Reports. 6.
    32. Engineering T cells to target tumor cells. 71-101.
    33. Erratum. Blood. 126:2527.
    34. Combining gene therapy and nanomedicine to enhance the therapeutic potential of T cells. 376-379.
    35. Translational implications for off-the-shelf immune cells expressing chimeric antigen receptors. Molecular Therapy. 24:1178-1186.
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