Connection

Co-Authors

This is a "connection" page, showing publications co-authored by DAVID TWEARDY and MOSES MAKOKHA KASEMBELI.
Connection Strength

5.710
  1. Aberrant function of pathogenic STAT3 mutant proteins is linked to altered stability of monomers and homodimers. Blood. 2023 03 23; 141(12):1411-1424.
    View in: PubMed
    Score: 0.886
  2. Corrigendum to "TTI-101: A competitive inhibitor of STAT3 that spares oxidative phosphorylation and reverses mechanical allodynia in mouse models of neuropathic pain" [Biochem. Pharmacol. 192 (2021) 114688]. Biochem Pharmacol. 2022 Jan; 195:114860.
    View in: PubMed
    Score: 0.809
  3. TTI-101: A competitive inhibitor of STAT3 that spares oxidative phosphorylation and reverses mechanical allodynia in mouse models of neuropathic pain. Biochem Pharmacol. 2021 10; 192:114688.
    View in: PubMed
    Score: 0.788
  4. Contribution of STAT3 to Inflammatory and Fibrotic Diseases and Prospects for its Targeting for Treatment. Int J Mol Sci. 2018 Aug 05; 19(8).
    View in: PubMed
    Score: 0.643
  5. Modulation of STAT3 folding and function by TRiC/CCT chaperonin. PLoS Biol. 2014 Apr; 12(4):e1001844.
    View in: PubMed
    Score: 0.477
  6. SH2 domain binding to phosphopeptide ligands: potential for drug targeting. Front Biosci (Landmark Ed). 2009 01 01; 14(3):1010-22.
    View in: PubMed
    Score: 0.331
  7. Novel STAT3 small-molecule inhibitors identified by structure-based virtual ligand screening incorporating SH2 domain flexibility. Pharmacol Res. 2021 07; 169:105637.
    View in: PubMed
    Score: 0.194
  8. Targeting Janus Kinases and Signal Transducer and Activator of Transcription 3 to Treat Inflammation, Fibrosis, and Cancer: Rationale, Progress, and Caution. Pharmacol Rev. 2020 04; 72(2):486-526.
    View in: PubMed
    Score: 0.180
  9. Correction: Small-molecule inhibition of STAT3 in radioresistant head and neck squamous cell carcinoma. Oncotarget. 2019 02 22; 10(16):1603.
    View in: PubMed
    Score: 0.167
  10. Protein stabilization improves STAT3 function in autosomal dominant hyper-IgE syndrome. Blood. 2016 12 29; 128(26):3061-3072.
    View in: PubMed
    Score: 0.142
  11. Small-molecule inhibition of STAT3 in radioresistant head and neck squamous cell carcinoma. Oncotarget. 2016 May 03; 7(18):26307-30.
    View in: PubMed
    Score: 0.137
  12. Substance P Receptor Signaling Mediates Doxorubicin-Induced Cardiomyocyte Apoptosis and Triple-Negative Breast Cancer Chemoresistance. Biomed Res Int. 2016; 2016:1959270.
    View in: PubMed
    Score: 0.135
  13. Contribution of the Type II Chaperonin, TRiC/CCT, to Oncogenesis. Int J Mol Sci. 2015 Nov 06; 16(11):26706-20.
    View in: PubMed
    Score: 0.133
  14. Small-molecule targeting of signal transducer and activator of transcription (STAT) 3 to treat non-small cell lung cancer. Lung Cancer. 2015 Nov; 90(2):182-90.
    View in: PubMed
    Score: 0.131
  15. Contribution of chaperones to STAT pathway signaling. JAKSTAT. 2014; 3(3):e970459.
    View in: PubMed
    Score: 0.124
  16. Monoclonal Antibodies Specific for STAT3? Reveal Its Contribution to Constitutive STAT3 Phosphorylation in Breast Cancer. Cancers (Basel). 2014 Sep 29; 6(4):2012-34.
    View in: PubMed
    Score: 0.123
  17. Chemical probes that competitively and selectively inhibit Stat3 activation. PLoS One. 2009; 4(3):e4783.
    View in: PubMed
    Score: 0.084
  18. Pharmacokinetics and pharmacodynamics of TTI-101, a STAT3 inhibitor that blocks muscle proteolysis in rats with chronic kidney disease. Am J Physiol Renal Physiol. 2020 07 01; 319(1):F84-F92.
    View in: PubMed
    Score: 0.046
  19. Targeting STAT3 anti-apoptosis pathways with organic and hybrid organic-inorganic inhibitors. Org Biomol Chem. 2020 05 06; 18(17):3288-3296.
    View in: PubMed
    Score: 0.045
  20. Chaperonin TRiC/CCT Recognizes Fusion Oncoprotein AML1-ETO through Subunit-Specific Interactions. Biophys J. 2016 06 07; 110(11):2377-2385.
    View in: PubMed
    Score: 0.035
  21. PARP Inhibition Suppresses Growth of EGFR-Mutant Cancers by Targeting Nuclear PKM2. Cell Rep. 2016 Apr 26; 15(4):843-856.
    View in: PubMed
    Score: 0.034
  22. Chaperonin TRiC/CCT Modulates the Folding and Activity of Leukemogenic Fusion Oncoprotein AML1-ETO. J Biol Chem. 2016 Feb 26; 291(9):4732-41.
    View in: PubMed
    Score: 0.034
  23. Rhodium(II) Proximity-Labeling Identifies a Novel Target Site on STAT3 for Inhibitors with Potent Anti-Leukemia Activity. Angew Chem Int Ed Engl. 2015 Oct 26; 54(44):13085-9.
    View in: PubMed
    Score: 0.033
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.