EDWARDWEINMANEDWARD WEINMAN11006WEINMAN, EDWARDClinical Professorprns:coAuthorOfcoauthor ofprns:endDateend dateFaculty Rankprns:fullNamefull nameprns:grantAwardedBygrant awarded byprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:principalInvestigatorNameprincipal investigator nameprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:startDatestart dateprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressvivo:address1address line 1vivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provinceAgreementvivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentDivisionGrantvivo:hasResearchArearesearch areasvivo:hasResearcherRoleresearch activitiesvivo:hrJobTitleHR job titleInformation Resourcevivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:personInPositionpositionsPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titleResearcher Rolevivo:researcherRoleOfresearcher role ofRolevivo:roleContributesTocontributes tovivo:sponsorAwardIdsponsor award idrdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonExperimental Radiation OncologyMolecular & Cellular OncologyPain MedicineSystems BiologyMD AndersonMIEN-CHIEHUNGMIEN-CHIE HUNG8427HUNG, MIEN-CHIEProfessorGORDON BMILLSGORDON B MILLS8620MILLS, GORDON BProfessorJUNJIECHENJUNJIE CHEN8830CHEN, JUNJIEProfessorZHIZHONG ZPANZHIZHONG Z PAN8885PAN, ZHIZHONG ZProfessor20410114Bie B, Zhang Z, Cai YQ, Zhu W, Zhang Y, Dai J, Lowenstein CJ, Weinman EJ, Pan ZZThe Journal of neuroscience : the official journal of the Society for NeuroscienceNerve growth factor-regulated emergence of functional delta-opioid receptors. J Neurosci. 2010 Apr 21; 30(16):5617-28.J Neurosci2010-04-21T00:00:002010Nerve growth factor-regulated emergence of functional delta-opioid receptors.One Baylor PlazaHouston, 77030TX7.050650.0028197277research areas0.09519180.09519181coauthor of34.19776.3413760similar to1152selected publicationsAuthorship 2815294Authorship 28165713Authorship 2818651Authorship 2819195Authorship 2819897Authorship 2820474Authorship 2821082Authorship 28220013Authorship 2829599Authorship 2832661Authorship 2836711Authorship 2838976Authorship 2839018Authorship 2840055Authorship 2840561Authorship 2843263Authorship 2843721Authorship 2843972Authorship 2846322Authorship 2851611Authorship 2857291Authorship 2859024Authorship 2861698Authorship 2972704Authorship 3044426Authorship 3048886Authorship 3126561Authorship 3126997Authorship 3128803Authorship 3130499Authorship 3130507Authorship 3131051Authorship 3133641Authorship 3135195Authorship 3136433Authorship 3137697Authorship 3139764Authorship 3141901Authorship 3142372Authorship 3143081Authorship 3143115Authorship 3143125Authorship 3143968Authorship 3145391Authorship 3147151Authorship 3148467Authorship 3150587Authorship 3152841212586353Weinman EJ, Steplock D, Shenolikar SFEBS lettersNHERF-1 uniquely transduces the cAMP signals that inhibit sodium-hydrogen exchange in mouse renal apical membranes. FEBS Lett. 2003 Feb 11; 536(1-3):141-4.FEBS Lett2003-02-11T00:00:002003NHERF-1 uniquely transduces the cAMP signals that inhibit sodium-hydrogen exchange in mouse renal apical membranes.12606316Khadeer MA, Tang Z, Tenenhouse HS, Eiden MV, Murer H, Hernando N, Weinman EJ, Chellaiah MA, Gupta AAmerican journal of physiology. Cell physiologyNa+-dependent phosphate transporters in the murine osteoclast: cellular distribution and protein interactions. Am J Physiol Cell Physiol. 2003 Jun; 284(6):C1633-44.Am J Physiol Cell Physiol2003-02-26T00:00:002003Na+-dependent phosphate transporters in the murine osteoclast: cellular distribution and protein interactions.12819230Lederer ED, Khundmiri SJ, Weinman EJJournal of the American Society of Nephrology : JASNRole of NHERF-1 in regulation of the activity of Na-K ATPase and sodium-phosphate co-transport in epithelial cells. J Am Soc Nephrol. 2003 Jul; 14(7):1711-9.J Am Soc Nephrol2003-07-01T00:00:002003Role of NHERF-1 in regulation of the activity of Na-K ATPase and sodium-phosphate co-transport in epithelial cells.12917102Wade JB, Liu J, Coleman RA, Cunningham R, Steplock DA, Lee-Kwon W, Pallone TL, Shenolikar S, Weinman EJAmerican journal of physiology. Cell physiologyLocalization and interaction of NHERF isoforms in the renal proximal tubule of the mouse. Am J Physiol Cell Physiol. 2003 Dec; 285(6):C1494-503.Am J Physiol Cell Physiol2003-08-13T00:00:002003Localization and interaction of NHERF isoforms in the renal proximal tubule of the mouse.12920119Sneddon WB, Syme CA, Bisello A, Magyar CE, Rochdi MD, Parent JL, Weinman EJ, Abou-Samra AB, Friedman PAThe Journal of biological chemistryActivation-independent parathyroid hormone receptor internalization is regulated by NHERF1 (EBP50). J Biol Chem. 2003 Oct 31; 278(44):43787-96.J Biol Chem2003-08-14T00:00:002003Activation-independent parathyroid hormone receptor internalization is regulated by NHERF1 (EBP50).12952857Weinman EJ, Boddeti A, Cunningham R, Akom M, Wang F, Wang Y, Liu J, Steplock D, Shenolikar S, Wade JBAmerican journal of physiology. Renal physiologyNHERF-1 is required for renal adaptation to a low-phosphate diet. Am J Physiol Renal Physiol. 2003 Dec; 285(6):F1225-32.Am J Physiol Renal Physiol2003-09-02T00:00:002003NHERF-1 is required for renal adaptation to a low-phosphate diet.14580213Weinman EJ, Wang Y, Wang F, Greer C, Steplock D, Shenolikar SBiochemistryA C-terminal PDZ motif in NHE3 binds NHERF-1 and enhances cAMP inhibition of sodium-hydrogen exchange. Biochemistry. 2003 Nov 04; 42(43):12662-8.Biochemistry2003-11-04T00:00:002003A C-terminal PDZ motif in NHE3 binds NHERF-1 and enhances cAMP inhibition of sodium-hydrogen exchange.14706641Boehmer C, Embark HM, Bauer A, Palmada M, Yun CH, Weinman EJ, Endou H, Cohen P, Lahme S, Bichler KH, Lang FBiochemical and biophysical research communicationsStimulation of renal Na+ dicarboxylate cotransporter 1 by Na+/H+ exchanger regulating factor 2, serum and glucocorticoid inducible kinase isoforms, and protein kinase B. Biochem Biophys Res Commun. 2004 Jan 23; 313(4):998-1003.Biochem Biophys Res Commun2004-01-23T00:00:002004Stimulation of renal Na+ dicarboxylate cotransporter 1 by Na+/H+ exchanger regulating factor 2, serum and glucocorticoid inducible kinase isoforms, and protein kinase B.15070904Huang P, Steplock D, Weinman EJ, Hall RA, Ding Z, Li J, Wang Y, Liu-Chen LYThe Journal of biological chemistrykappa Opioid receptor interacts with Na(+)/H(+)-exchanger regulatory factor-1/Ezrin-radixin-moesin-binding phosphoprotein-50 (NHERF-1/EBP50) to stimulate Na(+)/H(+) exchange independent of G(i)/G(o) proteins. J Biol Chem. 2004 Jun 11; 279(24):25002-9.J Biol Chem2004-04-07T00:00:002004kappa Opioid receptor interacts with Na(+)/H(+)-exchanger regulatory factor-1/Ezrin-radixin-moesin-binding phosphoprotein-50 (NHERF-1/EBP50) to stimulate Na(+)/H(+) exchange independent of G(i)/G(o) proteins.15218020Cunningham R, Steplock D, Wang F, Huang H, E X, Shenolikar S, Weinman EJThe Journal of biological chemistryDefective parathyroid hormone regulation of NHE3 activity and phosphate adaptation in cultured NHERF-1-/- renal proximal tubule cells. J Biol Chem. 2004 Sep 03; 279(36):37815-21.J Biol Chem2004-06-24T00:00:002004Defective parathyroid hormone regulation of NHE3 activity and phosphate adaptation in cultured NHERF-1-/- renal proximal tubule cells.15546854Shenolikar S, Voltz JW, Cunningham R, Weinman EJPhysiology (Bethesda, Md.)Regulation of ion transport by the NHERF family of PDZ proteins. Physiology (Bethesda). 2004 Dec; 19:362-9.Physiology (Bethesda)2004-12-01T00:00:002004Regulation of ion transport by the NHERF family of PDZ proteins.15742180Weinman EJ, Cunningham R, Shenolikar SPflugers Archiv : European journal of physiologyNHERF and regulation of the renal sodium-hydrogen exchanger NHE3. Pflugers Arch. 2005 Jun; 450(3):137-44.Pflugers Arch2005-03-02T00:00:002005NHERF and regulation of the renal sodium-hydrogen exchanger NHE3.15932893Weinman EJ, Cunningham R, Wade JB, Shenolikar SThe Journal of physiologyThe role of NHERF-1 in the regulation of renal proximal tubule sodium-hydrogen exchanger 3 and sodium-dependent phosphate cotransporter 2a. J Physiol. 2005 Aug 15; 567(Pt 1):27-32.J Physiol2005-06-02T00:00:002005The role of NHERF-1 in the regulation of renal proximal tubule sodium-hydrogen exchanger 3 and sodium-dependent phosphate cotransporter 2a.15942052Wang Y, Cai H, Cebotaru L, Hryciw DH, Weinman EJ, Donowitz M, Guggino SE, Guggino WBAmerican journal of physiology. Renal physiologyClC-5: role in endocytosis in the proximal tubule. Am J Physiol Renal Physiol. 2005 Oct; 289(4):F850-62.Am J Physiol Renal Physiol2005-06-07T00:00:002005ClC-5: role in endocytosis in the proximal tubule.15942053Cunningham R, E X, Steplock D, Shenolikar S, Weinman EJAmerican journal of physiology. Renal physiologyDefective PTH regulation of sodium-dependent phosphate transport in NHERF-1-/- renal proximal tubule cells and wild-type cells adapted to low-phosphate media. Am J Physiol Renal Physiol. 2005 Oct; 289(4):F933-8.Am J Physiol Renal Physiol2005-06-07T00:00:002005Defective PTH regulation of sodium-dependent phosphate transport in NHERF-1-/- renal proximal tubule cells and wild-type cells adapted to low-phosphate media.16000700Khundmiri SJ, Weinman EJ, Steplock D, Cole J, Ahmad A, Baumann PD, Barati M, Rane MJ, Lederer EJournal of the American Society of Nephrology : JASNParathyroid hormone regulation of NA+,K+-ATPase requires the PDZ 1 domain of sodium hydrogen exchanger regulatory factor-1 in opossum kidney cells. J Am Soc Nephrol. 2005 Sep; 16(9):2598-607.J Am Soc Nephrol2005-07-06T00:00:002005Parathyroid hormone regulation of NA+,K+-ATPase requires the PDZ 1 domain of sodium hydrogen exchanger regulatory factor-1 in opossum kidney cells.16203733Guerra L, Fanelli T, Favia M, Riccardi SM, Busco G, Cardone RA, Carrabino S, Weinman EJ, Reshkin SJ, Conese M, Casavola VThe Journal of biological chemistryNa+/H+ exchanger regulatory factor isoform 1 overexpression modulates cystic fibrosis transmembrane conductance regulator (CFTR) expression and activity in human airway 16HBE14o- cells and rescues DeltaF508 CFTR functional expression in cystic fibrosis cells. J Biol Chem. 2005 Dec 09; 280(49):40925-33.J Biol Chem2005-10-03T00:00:002005Na+/H+ exchanger regulatory factor isoform 1 overexpression modulates cystic fibrosis transmembrane conductance regulator (CFTR) expression and activity in human airway 16HBE14o- cells and rescues DeltaF508 CFTR functional expression in cystic fibrosis cells.16249272Weinman EJ, Mohanlal V, Stoycheff N, Wang F, Steplock D, Shenolikar S, Cunningham RAmerican journal of physiology. Renal physiologyLongitudinal study of urinary excretion of phosphate, calcium, and uric acid in mutant NHERF-1 null mice. Am J Physiol Renal Physiol. 2006 Apr; 290(4):F838-43.Am J Physiol Renal Physiol2005-10-25T00:00:002005Longitudinal study of urinary excretion of phosphate, calcium, and uric acid in mutant NHERF-1 null mice.16460281Weinman EJ, Hall RA, Friedman PA, Liu-Chen LY, Shenolikar SAnnual review of physiologyThe association of NHERF adaptor proteins with g protein-coupled receptors and receptor tyrosine kinases. Annu Rev Physiol. 2006; 68:491-505.Annu Rev Physiol2006-01-01T00:00:002006The association of NHERF adaptor proteins with g protein-coupled receptors and receptor tyrosine kinases.16705152Cunningham R, Steplock D, E X, Biswas RS, Wang F, Shenolikar S, Weinman EJAmerican journal of physiology. Renal physiologyAdenoviral expression of NHERF-1 in NHERF-1 null mouse renal proximal tubule cells restores Npt2a regulation by low phosphate media and parathyroid hormone. Am J Physiol Renal Physiol. 2006 Oct; 291(4):F896-901.Am J Physiol Renal Physiol2006-05-16T00:00:002006Adenoviral expression of NHERF-1 in NHERF-1 null mouse renal proximal tubule cells restores Npt2a regulation by low phosphate media and parathyroid hormone.16987995Capuano P, Bacic D, Roos M, Gisler SM, Stange G, Biber J, Kaissling B, Weinman EJ, Shenolikar S, Wagner CA, Murer HAmerican journal of physiology. Cell physiologyDefective coupling of apical PTH receptors to phospholipase C prevents internalization of the Na+-phosphate cotransporter NaPi-IIa in Nherf1-deficient mice. Am J Physiol Cell Physiol. 2007 Feb; 292(2):C927-34.Am J Physiol Cell Physiol2006-09-20T00:00:002006Defective coupling of apical PTH receptors to phospholipase C prevents internalization of the Na+-phosphate cotransporter NaPi-IIa in Nherf1-deficient mice.17332506Cardone RA, Bellizzi A, Busco G, Weinman EJ, Dell'Aquila ME, Casavola V, Azzariti A, Mangia A, Paradiso A, Reshkin SJMolecular biology of the cellThe NHERF1 PDZ2 domain regulates PKA-RhoA-p38-mediated NHE1 activation and invasion in breast tumor cells. Mol Biol Cell. 2007 May; 18(5):1768-80.Mol Biol Cell2007-03-01T00:00:002007The NHERF1 PDZ2 domain regulates PKA-RhoA-p38-mediated NHE1 activation and invasion in breast tumor cells.17409311Cunningham R, Brazie M, Kanumuru S, E X, Biswas R, Wang F, Steplock D, Wade JB, Anzai N, Endou H, Shenolikar S, Weinman EJJournal of the American Society of Nephrology : JASNSodium-hydrogen exchanger regulatory factor-1 interacts with mouse urate transporter 1 to regulate renal proximal tubule uric acid transport. J Am Soc Nephrol. 2007 May; 18(5):1419-25.J Am Soc Nephrol2007-04-04T00:00:002007Sodium-hydrogen exchanger regulatory factor-1 interacts with mouse urate transporter 1 to regulate renal proximal tubule uric acid transport.17580307Murtazina R, Kovbasnjuk O, Zachos NC, Li X, Chen Y, Hubbard A, Hogema BM, Steplock D, Seidler U, Hoque KM, Tse CM, De Jonge HR, Weinman EJ, Donowitz MThe Journal of biological chemistryTissue-specific regulation of sodium/proton exchanger isoform 3 activity in Na(+)/H(+) exchanger regulatory factor 1 (NHERF1) null mice. cAMP inhibition is differentially dependent on NHERF1 and exchange protein directly activated by cAMP in ileum versus proximal tubule. J Biol Chem. 2007 Aug 24; 282(34):25141-51.J Biol Chem2007-06-19T00:00:002007Tissue-specific regulation of sodium/proton exchanger isoform 3 activity in Na(+)/H(+) exchanger regulatory factor 1 (NHERF1) null mice. cAMP inhibition is differentially dependent on NHERF1 and exchange protein directly activated by cAMP in ileum versus proximal tubule.17895247Voltz JW, Brush M, Sikes S, Steplock D, Weinman EJ, Shenolikar SThe Journal of biological chemistryPhosphorylation of PDZ1 domain attenuates NHERF-1 binding to cellular targets. J Biol Chem. 2007 Nov 16; 282(46):33879-33887.J Biol Chem2007-09-25T00:00:002007Phosphorylation of PDZ1 domain attenuates NHERF-1 binding to cellular targets.17947234Broere N, Hillesheim J, Tuo B, Jorna H, Houtsmuller AB, Shenolikar S, Weinman EJ, Donowitz M, Seidler U, de Jonge HR, Hogema BMThe Journal of biological chemistryCystic fibrosis transmembrane conductance regulator activation is reduced in the small intestine of Na+/H+ exchanger 3 regulatory factor 1 (NHERF-1)- but Not NHERF-2-deficient mice. J Biol Chem. 2007 Dec 28; 282(52):37575-84.J Biol Chem2007-10-18T00:00:002007Cystic fibrosis transmembrane conductance regulator activation is reduced in the small intestine of Na+/H+ exchanger 3 regulatory factor 1 (NHERF-1)- but Not NHERF-2-deficient mice.17975671Weinman EJ, Biswas RS, Peng G, Peng Q, Shen L, Turner CL, E X, Steplock D, Shenolikar S, Cunningham RThe Journal of clinical investigationParathyroid hormone inhibits renal phosphate transport by phosphorylation of serine 77 of sodium-hydrogen exchanger regulatory factor-1. J Clin Invest. 2007 Nov; 117(11):3412-20.J Clin Invest2007-11-01T00:00:002007Parathyroid hormone inhibits renal phosphate transport by phosphorylation of serine 77 of sodium-hydrogen exchanger regulatory factor-1.18190691Pan Y, Weinman EJ, Dai JLBreast cancer research : BCRNa+/H+ exchanger regulatory factor 1 inhibits platelet-derived growth factor signaling in breast cancer cells. Breast Cancer Res. 2008; 10(1):R5.Breast Cancer Res2008-01-11T00:00:002008Na+/H+ exchanger regulatory factor 1 inhibits platelet-derived growth factor signaling in breast cancer cells.18216150Khundmiri SJ, Ahmad A, Bennett RE, Weinman EJ, Steplock D, Cole J, Baumann PD, Lewis J, Singh S, Clark BJ, Lederer EDAmerican journal of physiology. Renal physiologyNovel regulatory function for NHERF-1 in Npt2a transcription. Am J Physiol Renal Physiol. 2008 Apr; 294(4):F840-9.Am J Physiol Renal Physiol2008-01-23T00:00:002008Novel regulatory function for NHERF-1 in Npt2a transcription.18256311Cunningham R, Esmaili A, Brown E, Biswas RS, Murtazina R, Donowitz M, Dijkman HB, van der Vlag J, Hogema BM, De Jonge HR, Shenolikar S, Wade JB, Weinman EJAmerican journal of physiology. Renal physiologyUrine electrolyte, mineral, and protein excretion in NHERF-2 and NHERF-1 null mice. Am J Physiol Renal Physiol. 2008 Apr; 294(4):F1001-7.Am J Physiol Renal Physiol2008-02-06T00:00:002008Urine electrolyte, mineral, and protein excretion in NHERF-2 and NHERF-1 null mice.19221439Singh AK, Riederer B, Krabbenh?ft A, Rausch B, Bonhagen J, Lehmann U, de Jonge HR, Donowitz M, Yun C, Weinman EJ, Kocher O, Hogema BM, Seidler UThe Journal of clinical investigationDifferential roles of NHERF1, NHERF2, and PDZK1 in regulating CFTR-mediated intestinal anion secretion in mice. J Clin Invest. 2009 Mar; 119(3):540-50.J Clin Invest2009-02-16T00:00:002009Differential roles of NHERF1, NHERF2, and PDZK1 in regulating CFTR-mediated intestinal anion secretion in mice.19794105Weinman EJ, Steplock D, Cha B, Kovbasnjuk O, Frost NA, Cunningham R, Shenolikar S, Blanpied TA, Donowitz MAmerican journal of physiology. Renal physiologyPTH transiently increases the percent mobile fraction of Npt2a in OK cells as determined by FRAP. Am J Physiol Renal Physiol. 2009 Dec; 297(6):F1560-5.Am J Physiol Renal Physiol2009-09-30T00:00:002009PTH transiently increases the percent mobile fraction of Npt2a in OK cells as determined by FRAP.20200151Weinman EJ, Biswas R, Steplock D, Douglass TS, Cunningham R, Shenolikar SThe Journal of biological chemistrySodium-hydrogen exchanger regulatory factor 1 (NHERF-1) transduces signals that mediate dopamine inhibition of sodium-phosphate co-transport in mouse kidney. J Biol Chem. 2010 Apr 30; 285(18):13454-60.J Biol Chem2010-03-03T00:00:002010Sodium-hydrogen exchanger regulatory factor 1 (NHERF-1) transduces signals that mediate dopamine inhibition of sodium-phosphate co-transport in mouse kidney.20404332Li M, Wang W, Soroka CJ, Mennone A, Harry K, Weinman EJ, Boyer JLThe Journal of biological chemistryNHERF-1 binds to Mrp2 and regulates hepatic Mrp2 expression and function. J Biol Chem. 2010 Jun 18; 285(25):19299-307.J Biol Chem2010-04-19T00:00:002010NHERF-1 binds to Mrp2 and regulates hepatic Mrp2 expression and function.20571032Weinman EJ, Steplock D, Zhang Y, Biswas R, Bloch RJ, Shenolikar SThe Journal of biological chemistryCooperativity between the phosphorylation of Thr95 and Ser77 of NHERF-1 in the hormonal regulation of renal phosphate transport. J Biol Chem. 2010 Aug 13; 285(33):25134-8.J Biol Chem2010-06-22T00:00:002010Cooperativity between the phosphorylation of Thr95 and Ser77 of NHERF-1 in the hormonal regulation of renal phosphate transport.20632170Cunningham R, Biswas R, Steplock D, Shenolikar S, Weinman EUrological researchRole of NHERF and scaffolding proteins in proximal tubule transport. Urol Res. 2010 Aug; 38(4):257-62.Urol Res2010-07-15T00:00:002010Role of NHERF and scaffolding proteins in proximal tubule transport.21048030Weinman EJ, Steplock D, Shenolikar S, Blanpied TAAmerican journal of physiology. Renal physiologyDynamics of PTH-induced disassembly of Npt2a/NHERF-1 complexes in living OK cells. Am J Physiol Renal Physiol. 2011 Jan; 300(1):F231-5.Am J Physiol Renal Physiol2010-11-03T00:00:002010Dynamics of PTH-induced disassembly of Npt2a/NHERF-1 complexes in living OK cells.21063698Evan AP, Weinman EJ, Wu XR, Lingeman JE, Worcester EM, Coe FLUrological researchComparison of the pathology of interstitial plaque in human ICSF stone patients to NHERF-1 and THP-null mice. Urol Res. 2010 Dec; 38(6):439-52.Urol Res2010-11-10T00:00:002010Comparison of the pathology of interstitial plaque in human ICSF stone patients to NHERF-1 and THP-null mice.21160026Salyer S, Lesousky N, Weinman EJ, Clark BJ, Lederer ED, Khundmiri SJAmerican journal of physiology. Cell physiologyDopamine regulation of Na+-K+-ATPase requires the PDZ-2 domain of sodium hydrogen regulatory factor-1 (NHERF-1) in opossum kidney cells. Am J Physiol Cell Physiol. 2011 Mar; 300(3):C425-34.Am J Physiol Cell Physiol2010-12-15T00:00:002010Dopamine regulation of Na+-K+-ATPase requires the PDZ-2 domain of sodium hydrogen regulatory factor-1 (NHERF-1) in opossum kidney cells.21406291Blaine J, Weinman EJ, Cunningham RAdvances in chronic kidney diseaseThe regulation of renal phosphate transport. Adv Chronic Kidney Dis. 2011 Mar; 18(2):77-84.Adv Chronic Kidney Dis2011-03-01T00:00:002011The regulation of renal phosphate transport.21908609Weinman EJ, Steplock D, Shenolikar S, Biswas RThe Journal of biological chemistryFibroblast growth factor-23-mediated inhibition of renal phosphate transport in mice requires sodium-hydrogen exchanger regulatory factor-1 (NHERF-1) and synergizes with parathyroid hormone. J Biol Chem. 2011 Oct 28; 286(43):37216-21.J Biol Chem2011-09-09T00:00:002011Fibroblast growth factor-23-mediated inhibition of renal phosphate transport in mice requires sodium-hydrogen exchanger regulatory factor-1 (NHERF-1) and synergizes with parathyroid hormone.22496422Cardone RA, Greco MR, Capulli M, Weinman EJ, Busco G, Bellizzi A, Casavola V, Antelmi E, Ambruosi B, Dell'Aquila ME, Paradiso A, Teti A, Rucci N, Reshkin SJMolecular biology of the cellNHERF1 acts as a molecular switch to program metastatic behavior and organotropism via its PDZ domains. Mol Biol Cell. 2012 Jun; 23(11):2028-40.Mol Biol Cell2012-04-11T00:00:002012NHERF1 acts as a molecular switch to program metastatic behavior and organotropism via its PDZ domains.22535796Weinman EJ, Lederer EDAmerican journal of physiology. Renal physiologyNHERF-1 and the regulation of renal phosphate reabsoption: a tale of three hormones. Am J Physiol Renal Physiol. 2012 Aug 01; 303(3):F321-7.Am J Physiol Renal Physiol2012-04-25T00:00:002012NHERF-1 and the regulation of renal phosphate reabsoption: a tale of three hormones.22904329Giral H, Cranston D, Lanzano L, Caldas Y, Sutherland E, Rachelson J, Dobrinskikh E, Weinman EJ, Doctor RB, Gratton E, Levi MThe Journal of biological chemistryNHE3 regulatory factor 1 (NHERF1) modulates intestinal sodium-dependent phosphate transporter (NaPi-2b) expression in apical microvilli. J Biol Chem. 2012 Oct 12; 287(42):35047-35056.J Biol Chem2012-08-17T00:00:002012NHE3 regulatory factor 1 (NHERF1) modulates intestinal sodium-dependent phosphate transporter (NaPi-2b) expression in apical microvilli.25995109Ketchem CJ, Khundmiri SJ, Gaweda AE, Murray R, Clark BJ, Weinman EJ, Lederer EDAmerican journal of physiology. Renal physiologyRole of Na+/H+ exchanger regulatory factor 1 in forward trafficking of the type IIa Na+-Pi cotransporter. Am J Physiol Renal Physiol. 2015 Jul 15; 309(2):F109-19.Am J Physiol Renal Physiol2015-07-15T00:00:002015Role of Na+/H+ exchanger regulatory factor 1 in forward trafficking of the type IIa Na+-Pi cotransporter.26108984Li M, Mennone A, Soroka CJ, Hagey LR, Ouyang X, Weinman EJ, Boyer JLHepatology (Baltimore, Md.)Na(+) /H(+) exchanger regulatory factor 1 knockout mice have an attenuated hepatic inflammatory response and are protected from cholestatic liver injury. Hepatology. 2015 Oct; 62(4):1227-36.Hepatology2015-08-22T00:00:002015Na(+) /H(+) exchanger regulatory factor 1 knockout mice have an attenuated hepatic inflammatory response and are protected from cholestatic liver injury.26258413He P, Zhao L, Zhu L, Weinman EJ, De Giorgio R, Koval M, Srinivasan S, Yun CCThe Journal of clinical investigationRestoration of Na+/H+ exchanger NHE3-containing macrocomplexes ameliorates diabetes-associated fluid loss. J Clin Invest. 2015 Sep; 125(9):3519-31.J Clin Invest2015-08-10T00:00:002015Restoration of Na+/H+ exchanger NHE3-containing macrocomplexes ameliorates diabetes-associated fluid loss.74Professor33Clinical Professor84Research Assistant ProfessorAuthorship 868920628392297Ritter-Makinson SL, Paquet M, Bogenpohl JW, Rodin RE, Chris Yun C, Weinman EJ, Smith Y, Hall RANeuroscienceGroup II metabotropic glutamate receptor interactions with NHERF scaffold proteins: Implications for receptor localization in brain. Neuroscience. 2017 06 14; 353:58-75.Neuroscience2017-04-07T00:00:002017Group II metabotropic glutamate receptor interactions with NHERF scaffold proteins: Implications for receptor localization in brain.Authorship 869875628515088Barati MT, Ketchem CJ, Merchant ML, Kusiak WB, Jose PA, Weinman EJ, LeBlanc AJ, Lederer ED, Khundmiri SJAmerican journal of physiology. Cell physiologyLoss of NHERF-1 expression prevents dopamine-mediated Na-K-ATPase regulation in renal proximal tubule cells from rat models of hypertension: aged F344 rats and spontaneously hypertensive rats. Am J Physiol Cell Physiol. 2017 Aug 01; 313(2):C197-C206.Am J Physiol Cell Physiol2017-05-17T00:00:002017Loss of NHERF-1 expression prevents dopamine-mediated Na-K-ATPase regulation in renal proximal tubule cells from rat models of hypertension: aged F344 rats and spontaneously hypertensive rats.true1Research Assistant ProfessorResearch Assistant Professortrue1ProfessorProfessorD017923Chemicals & Drugs381340.91689Sodium-Hydrogen ExchangersD007687Anatomy421420.904398Kidney Tubules, ProximalD010750Chemicals & Drugs51711550.647269PhosphoproteinsD010281Chemicals & Drugs831940.904752Parathyroid HormoneD010710Chemicals & Drugs1181910.904259Phosphates2014-03-31VAWEINMAN, EDWARD J2009-10-01NHERF-1 and dopamine-mediated regulation of renal phosphate transport.I01BX0001031996-09-29NIH/NIDDKWEINMAN, EDWARD J1987-04-01SODIUM/HYDROGEN ION TRANSPORT IN RENAL APICAL MEMBRANESR01DK0373192014-06-30NIH/NIDDKWEINMAN, EDWARD J1999-05-01NHERF-1 and PTH regulation of the renal transport of phosphate.R01DK055881Principal InvestigatorPrincipal InvestigatorPrincipal InvestigatorPharmacological & Pharmaceutical SciencesDepartment of MedicineMedicine-NephrologyBaylor College of MedicineUniversity of Houston College of PharmacyANEESBANDAYANEES AHMAD BANDAY43.05925700000000-89.468872800000004635BANDAY, ANEESResearch Assistant ProfessorMUSTAFALOKHANDWALAMUSTAFA F. LOKHANDWALA29.72602660000000-95.348164100000004614LOKHANDWALA, MUSTAFAProfessorAuthorship 945994631042404Pera T, Tompkins E, Katz M, Wang B, Deshpande DA, Weinman EJ, Penn RBFASEB journal : official publication of the Federation of American Societies for Experimental BiologySpecificity of NHERF1 regulation of GPCR signaling and function in human airway smooth muscle. FASEB J. 2019 08; 33(8):9008-9016.FASEB J2019-05-01T00:00:002019Specificity of NHERF1 regulation of GPCR signaling and function in human airway smooth muscle.Authorship 985164531904366Pushpakumar S, Ahmad A, Ketchem CJ, Jose PA, Weinman EJ, Sen U, Lederer ED, Khundmiri SJLife sciencesSodium-hydrogen exchanger regulatory factor-1 (NHERF1) confers salt sensitivity in both male and female models of hypertension in aging. Life Sci. 2020 Feb 15; 243:117226.Life Sci2020-01-03T00:00:002020Sodium-hydrogen exchanger regulatory factor-1 (NHERF1) confers salt sensitivity in both male and female models of hypertension in aging.true1Clinical ProfessorClinical Professortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessor