SHUJUFENGSHUJU FENG9673FENG, SHUJUAssistant Professorprns:coAuthorOfcoauthor ofFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressvivo:address1address line 1vivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provincevivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentDivisionvivo:hasResearchArearesearch areasvivo:hrJobTitleHR job titleInformation Resourcevivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:personInPositionpositionsPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPerson25395424Feng S, Liang X, Kroll MH, Chung DW, Afshar-Kharghan VBloodvon Willebrand factor is a cofactor in complement regulation. Blood. 2015 Feb 05; 125(6):1034-7.Blood2014-11-13T00:00:002014von Willebrand factor is a cofactor in complement regulation.2121 Holcombe BlvdHouston77030-4244TXAuthorship 1677751Authorship 1682631Authorship 1688173Authorship 1688471Authorship 1698561Authorship 1705442Authorship 1714731Authorship 1723901Authorship 1730821Authorship 1737631Authorship 1739942Authorship 1767941Authorship 1902572Authorship 1920601Authorship 1925581Authorship 1926353Authorship 19395419537256Matsubara A, Kan M, Feng S, McKeehan WLCancer researchInhibition of growth of malignant rat prostate tumor cells by restoration of fibroblast growth factor receptor 2. Cancer Res. 1998 Apr 01; 58(7):1509-14.Cancer Res1998-04-01T00:00:001998Inhibition of growth of malignant rat prostate tumor cells by restoration of fibroblast growth factor receptor 2.Pulmonary MedicineSystems BiologyMD AndersonGORDON BMILLSGORDON B MILLS8620MILLS, GORDON BProfessorMICHAELKROLLMICHAEL KROLL9534KROLL, MICHAELProfessorVAHIDAFSHAR-KHARGHANVAHID AFSHAR-KHARGHAN9499AFSHAR-KHARGHAN, VAHIDProfessor1.418880.00444682151research areas1.961920.03536945coauthor of23.05591.9084960similar to1123selected publicationsAuthorship 21800719393762Feng S, Wang F, Matsubara A, Kan M, McKeehan WLCancer researchFibroblast growth factor receptor 2 limits and receptor 1 accelerates tumorigenicity of prostate epithelial cells. Cancer Res. 1997 Dec 01; 57(23):5369-78.Cancer Res1997-12-01T00:00:001997Fibroblast growth factor receptor 2 limits and receptor 1 accelerates tumorigenicity of prostate epithelial cells.Authorship 26408859295338Wang F, Kan M, McKeehan K, Jang JH, Feng S, McKeehan WLThe Journal of biological chemistryA homeo-interaction sequence in the ectodomain of the fibroblast growth factor receptor. J Biol Chem. 1997 Sep 19; 272(38):23887-95.J Biol Chem1997-09-19T00:00:001997A homeo-interaction sequence in the ectodomain of the fibroblast growth factor receptor.9244177Feng S, Xu J, Wang F, Kan M, McKeehan WLBiochimica et biophysica actaNuclear localization of a complex of fibroblast growth factor(FGF)-1 and an NH2-terminal fragment of FGF receptor isoforms R4 and R1alpha in human liver cells. Biochim Biophys Acta. 1996 Jan 10; 1310(1):67-73.Biochim Biophys Acta1996-01-10T00:00:001996Nuclear localization of a complex of fibroblast growth factor(FGF)-1 and an NH2-terminal fragment of FGF receptor isoforms R4 and R1alpha in human liver cells.10627461Feng S, Christodoulides N, Res?ndiz JC, Berndt MC, Kroll MHBloodCytoplasmic domains of GpIbalpha and GpIbbeta regulate 14-3-3zeta binding to GpIb/IX/V. Blood. 2000 Jan 15; 95(2):551-7.Blood2000-01-15T00:00:002000Cytoplasmic domains of GpIbalpha and GpIbbeta regulate 14-3-3zeta binding to GpIb/IX/V.10361123Feng S, Christodoulides N, Kroll MHBloodThe glycoprotein Ib/IX complex regulates cell proliferation. Blood. 1999 Jun 15; 93(12):4256-63.Blood1999-06-15T00:00:001999The glycoprotein Ib/IX complex regulates cell proliferation.14717980Res?ndiz JC, Feng S, Ji G, Kroll MHJournal of thrombosis and haemostasis : JTHvon Willebrand factor binding to platelet glycoprotein Ib-IX-V stimulates the assembly of an alpha-actinin-based signaling complex. J Thromb Haemost. 2004 Jan; 2(1):161-9.J Thromb Haemost2004-01-01T00:00:002004von Willebrand factor binding to platelet glycoprotein Ib-IX-V stimulates the assembly of an alpha-actinin-based signaling complex.15623510Feng S, Lu X, Kroll MHThe Journal of biological chemistryFilamin A binding stabilizes nascent glycoprotein Ibalpha trafficking and thereby enhances its surface expression. J Biol Chem. 2005 Feb 25; 280(8):6709-15.J Biol Chem2004-12-28T00:00:002004Filamin A binding stabilizes nascent glycoprotein Ibalpha trafficking and thereby enhances its surface expression.74Professor10Assistant Professor78Professor Emeritus6Adjunct Professor11802708Feng S, Res?ndiz JC, Christodoulides N, Lu X, Arboleda D, Berndt MC, Kroll MHBiochemistryPathological shear stress stimulates the tyrosine phosphorylation of alpha-actinin associated with the glycoprotein Ib-IX complex. Biochemistry. 2002 Jan 29; 41(4):1100-8.Biochemistry2002-01-29T00:00:002002Pathological shear stress stimulates the tyrosine phosphorylation of alpha-actinin associated with the glycoprotein Ib-IX complex.12606772Res?ndiz JC, Feng S, Ji G, Francis KA, Berndt MC, Kroll MHMolecular pharmacologyPurinergic P2Y12 receptor blockade inhibits shear-induced platelet phosphatidylinositol 3-kinase activation. Mol Pharmacol. 2003 Mar; 63(3):639-45.Mol Pharmacol2003-03-01T00:00:002003Purinergic P2Y12 receptor blockade inhibits shear-induced platelet phosphatidylinositol 3-kinase activation.Authorship 373983116822941Feng S, Lu X, Res?ndiz JC, Kroll MHAmerican journal of physiology. Cell physiologyPathological shear stress directly regulates platelet alphaIIbbeta3 signaling. Am J Physiol Cell Physiol. 2006 Dec; 291(6):C1346-54.Am J Physiol Cell Physiol2006-07-05T00:00:002006Pathological shear stress directly regulates platelet alphaIIbbeta3 signaling.23116127Feng S, Kroll MH, Nolasco L, Moake J, Afshar-Kharghan VBritish journal of haematologyComplement activation in thrombotic microangiopathies. Br J Haematol. 2013 Feb; 160(3):404-6.Br J Haematol2012-11-01T00:00:002012Complement activation in thrombotic microangiopathies.Authorship 852404Authorship 865533Authorship 866403BloodAlpha actinin binds to glycoprotein (GP) IBA and functions as an adapter for phosphoinositide (PI) 3-kinase in shear stress-activated platelets. Blood. 96.Alpha actinin binds to glycoprotein (GP) IBA and functions as an adapter for phosphoinositide (PI) 3-kinase in shear stress-activated plateletsPlateletsPlatelets are not hyperreactive in patients with ovarian cancer. Platelets. 1-3.Platelets are not hyperreactive in patients with ovarian cancerBloodPhosphoinositide 3-kinase (pi3-k) is activated and associates with glycoprotein (gp) iba in platelets exposed to pathological shear stress. Blood. 96.Phosphoinositide 3-kinase (pi3-k) is activated and associates with glycoprotein (gp) iba in platelets exposed to pathological shear stress11323024Christodoulides N, Feng S, Res?ndiz JC, Berndt MC, Kroll MHThrombosis researchGlycoprotein Ib/IX/V binding to the membrane skeleton maintains shear-induced platelet aggregation. Thromb Res. 2001 Apr 15; 102(2):133-42.Thromb Res2001-04-15T00:00:002001Glycoprotein Ib/IX/V binding to the membrane skeleton maintains shear-induced platelet aggregation.12791664Feng S, Res?ndiz JC, Lu X, Kroll MHBloodFilamin A binding to the cytoplasmic tail of glycoprotein Ibalpha regulates von Willebrand factor-induced platelet activation. Blood. 2003 Sep 15; 102(6):2122-9.Blood2003-06-05T00:00:002003Filamin A binding to the cytoplasmic tail of glycoprotein Ibalpha regulates von Willebrand factor-induced platelet activation.15493507Sun L, Feng S, Res?ndiz JC, Lu X, Durante W, Kroll MHAnnals of biomedical engineeringRole of the Pyk2-MAP kinase-cPLA2 signaling pathway in shear-dependent platelet aggregation. Ann Biomed Eng. 2004 Sep; 32(9):1193-201.Ann Biomed Eng2004-09-01T00:00:002004Role of the Pyk2-MAP kinase-cPLA2 signaling pathway in shear-dependent platelet aggregation.16181038Kroll MH, Feng SExpert review of cardiovascular therapyTargeting shear stress-induced platelet activation: is lesion-specific antiplatelet therapy a realistic clinical goal? Expert Rev Cardiovasc Ther. 2005 Sep; 3(5):941-51.Expert Rev Cardiovasc Ther2005-09-01T00:00:002005Targeting shear stress-induced platelet activation: is lesion-specific antiplatelet therapy a realistic clinical goal?true1ProfessorProfessorD014841Chemicals & Drugs823350.817364von Willebrand FactorD003167Physiology68940.942171Complement ActivationD019038Chemicals & Drugs18730.961334Platelet Glycoprotein GPIb-IX ComplexD003165Chemicals & Drugs961390.917075Complement System ProteinsD001792Anatomy2827320.683567Blood PlateletsDepartment of MedicineDepartment of Molecular & Cellular BiologyMedicine-CardiologyMedicine-Hematology & OncologyMedicine-Thrombosis ResearchMolecular & Cellular BiologyBaylor College of MedicineJIANMINGXUJIANMING XU0.000000000000000.000000000000003458XU, JIANMINGProfessorMIGUELCRUZMIGUEL CRUZ0.000000000000000.00000000000000235CRUZ, MIGUELProfessorNEALKLEIMANNEAL KLEIMAN29.70991060000000-95.401413900000002919KLEIMAN, NEALAdjunct ProfessorJOELMOAKEJOEL MOAKE29.70508570000000-95.401808700000003057MOAKE, JOELProfessor Emeritus23847193Feng S, Eyler SJ, Zhang Y, Maga T, Nester CM, Kroll MH, Smith RJ, Afshar-Kharghan VBloodPartial ADAMTS13 deficiency in atypical hemolytic uremic syndrome. Blood. 2013 Aug 22; 122(8):1487-93.Blood2013-07-11T00:00:002013Partial ADAMTS13 deficiency in atypical hemolytic uremic syndrome.23991205Feng S, Liang X, Cruz MA, Vu H, Zhou Z, Pemmaraju N, Dong JF, Kroll MH, Afshar-Kharghan VPloS oneThe interaction between factor H and Von Willebrand factor. PLoS One. 2013; 8(8):e73715.PLoS One2013-08-26T00:00:002013The interaction between factor H and Von Willebrand factor.24008159Nolasco L, Nolasco J, Feng S, Afshar-Kharghan V, Moake JArteriosclerosis, thrombosis, and vascular biologyHuman complement factor H is a reductase for large soluble von Willebrand factor multimers--brief report. Arterioscler Thromb Vasc Biol. 2013 Nov; 33(11):2524-8.Arterioscler Thromb Vasc Biol2013-09-05T00:00:002013Human complement factor H is a reductase for large soluble von Willebrand factor multimers--brief report.true1ProfessorProfessortrue1Adjunct ProfessorAdjunct Professortrue1Professor EmeritusProfessor Emeritustrue1ProfessorProfessortrue1ProfessorProfessortrue1Assistant ProfessorAssistant Professortrue1ProfessorProfessor