DE PEILIDE PEI LI9325LI, DE PEIAssociate Professorprns:coAuthorOfcoauthor ofFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressvivo:address1address line 1vivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provincevivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentDivisionvivo:hasResearchArearesearch areasvivo:hrJobTitleHR job titleInformation Resourcevivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:personInPositionpositionsPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPerson1515 Holcombe BlvdHouston77030-4009TXAuthorship 1681791Authorship 1687383Authorship 1711752Authorship 1730601Authorship 1738581Authorship 1745732Authorship 1749623Authorship 1796681Authorship 1858052Authorship 1890493Authorship 1901781Authorship 1904371Authorship 1911405Authorship 1911618Authorship 1916715Authorship 1945634Authorship 1947952Authorship 194840710571655Li D, Zhang W, Sahin AA, Hittelman WNCancer detection and preventionDNA adducts in normal tissue adjacent to breast cancer: a review. Cancer Detect Prev. 1999; 23(6):454-62.Cancer Detect Prev1999-01-01T00:00:001999DNA adducts in normal tissue adjacent to breast cancer: a review.10828497Tong QC, Zhang Y, Li DP, Zhou ZN, Ji YHRegulatory peptidesThe blocking effect of BmP02, one novel short-chain scorpion peptide on transient outward K(+) channel of adult rat ventricular myocyte. Regul Pept. 2000 Jun 30; 90(1-3):85-92.Regul Pept2000-06-30T00:00:002000The blocking effect of BmP02, one novel short-chain scorpion peptide on transient outward K(+) channel of adult rat ventricular myocyte.12424303Pan YZ, Li DP, Chen SR, Pan HLJournal of neurophysiologyActivation of delta-opioid receptors excites spinally projecting locus coeruleus neurons through inhibition of GABAergic inputs. J Neurophysiol. 2002 Nov; 88(5):2675-83.J Neurophysiol2002-11-01T00:00:002002Activation of delta-opioid receptors excites spinally projecting locus coeruleus neurons through inhibition of GABAergic inputs.14678495Li DP, Chen SR, Finnegan TF, Pan HLThe Journal of physiologySignalling pathway of nitric oxide in synaptic GABA release in the rat paraventricular nucleus. J Physiol. 2004 Jan 01; 554(Pt 1):100-10.J Physiol2004-01-01T00:00:002004Signalling pathway of nitric oxide in synaptic GABA release in the rat paraventricular nucleus.15356178Li DP, Atnip LM, Chen SR, Pan HLJournal of neurophysiologyRegulation of synaptic inputs to paraventricular-spinal output neurons by alpha2 adrenergic receptors. J Neurophysiol. 2005 Jan; 93(1):393-402.J Neurophysiol2004-09-08T00:00:002004Regulation of synaptic inputs to paraventricular-spinal output neurons by alpha2 adrenergic receptors.15681656Li DP, Pan HLThe Journal of pharmacology and experimental therapeuticsAngiotensin II attenuates synaptic GABA release and excites paraventricular-rostral ventrolateral medulla output neurons. J Pharmacol Exp Ther. 2005 Jun; 313(3):1035-45.J Pharmacol Exp Ther2005-01-28T00:00:002005Angiotensin II attenuates synaptic GABA release and excites paraventricular-rostral ventrolateral medulla output neurons.16249372Chen Q, Li DP, Pan HLThe Journal of pharmacology and experimental therapeuticsPresynaptic alpha1 adrenergic receptors differentially regulate synaptic glutamate and GABA release to hypothalamic presympathetic neurons. J Pharmacol Exp Ther. 2006 Feb; 316(2):733-42.J Pharmacol Exp Ther2005-10-25T00:00:002005Presynaptic alpha1 adrenergic receptors differentially regulate synaptic glutamate and GABA release to hypothalamic presympathetic neurons.16410279Wang XL, Zhang HM, Li DP, Chen SR, Pan HLThe Journal of physiologyDynamic regulation of glycinergic input to spinal dorsal horn neurones by muscarinic receptor subtypes in rats. J Physiol. 2006 Mar 01; 571(Pt 2):403-13.J Physiol2006-01-12T00:00:002006Dynamic regulation of glycinergic input to spinal dorsal horn neurones by muscarinic receptor subtypes in rats.18567709Li DP, Yang Q, Pan HM, Pan HLAmerican journal of physiology. Heart and circulatory physiologyPlasticity of pre- and postsynaptic GABAB receptor function in the paraventricular nucleus in spontaneously hypertensive rats. Am J Physiol Heart Circ Physiol. 2008 Aug; 295(2):H807-15.Am J Physiol Heart Circ Physiol2008-06-20T00:00:002008Plasticity of pre- and postsynaptic GABAB receptor function in the paraventricular nucleus in spontaneously hypertensive rats.19850918Wu ZZ, Li DP, Chen SR, Pan HLThe Journal of biological chemistryAminopyridines potentiate synaptic and neuromuscular transmission by targeting the voltage-activated calcium channel beta subunit. J Biol Chem. 2009 Dec 25; 284(52):36453-36461.J Biol Chem2009-10-22T00:00:002009Aminopyridines potentiate synaptic and neuromuscular transmission by targeting the voltage-activated calcium channel beta subunit.22219297Li DP, Byan HS, Pan HLThe Journal of neuroscience : the official journal of the Society for NeuroscienceSwitch to glutamate receptor 2-lacking AMPA receptors increases neuronal excitability in hypothalamus and sympathetic drive in hypertension. J Neurosci. 2012 Jan 04; 32(1):372-80.J Neurosci2012-01-04T00:00:002012Switch to glutamate receptor 2-lacking AMPA receptors increases neuronal excitability in hypothalamus and sympathetic drive in hypertension.22474321Ye ZY, Li L, Li DP, Pan HLThe Journal of biological chemistryCasein kinase 2-mediated synaptic GluN2A up-regulation increases N-methyl-D-aspartate receptor activity and excitability of hypothalamic neurons in hypertension. J Biol Chem. 2012 May 18; 287(21):17438-17446.J Biol Chem2012-04-03T00:00:002012Casein kinase 2-mediated synaptic GluN2A up-regulation increases N-methyl-D-aspartate receptor activity and excitability of hypothalamic neurons in hypertension.22848558Cui F, Gao L, Yuan F, Dong ZF, Zhou ZN, Kline DD, Zhang Y, Li DPPloS oneHypobaric intermittent hypoxia attenuates hypoxia-induced depressor response. PLoS One. 2012; 7(7):e41656.PLoS One2012-07-27T00:00:002012Hypobaric intermittent hypoxia attenuates hypoxia-induced depressor response.24390226Xiong W, Chen SR, He L, Cheng K, Zhao YL, Chen H, Li DP, Homanics GE, Peever J, Rice KC, Wu LG, Pan HL, Zhang LNature neurosciencePresynaptic glycine receptors as a potential therapeutic target for hyperekplexia disease. Nat Neurosci. 2014 Feb; 17(2):232-9.Nat Neurosci2014-01-05T00:00:002014Presynaptic glycine receptors as a potential therapeutic target for hyperekplexia disease.24806793Pachuau J, Li DP, Chen SR, Lee HA, Pan HLJournal of neurochemistryProtein kinase CK2 contributes to diminished small conductance Ca2+-activated K+ channel activity of hypothalamic pre-sympathetic neurons in hypertension. J Neurochem. 2014 Sep; 130(5):657-67.J Neurochem2014-05-24T00:00:002014Protein kinase CK2 contributes to diminished small conductance Ca2+-activated K+ channel activity of hypothalamic pre-sympathetic neurons in hypertension.Anesthesiology & PeriOperative MedicineCritical CareGI Medical OncologyMD AndersonHUI-LINPANHUI-LIN PAN9317PAN, HUI-LINProfessorDONGHUILIDONGHUI LI8544LI, DONGHUIProfessor4.751190.00736317357research areas8.868440.029691912coauthor of248.1577.0883560similar to1175selected publicationsSHAO-RUICHENSHAO-RUI CHEN9326CHEN, SHAO-RUIAssociate ProfessorAuthorship 2176372Authorship 2179001Authorship 2183571Authorship 2184991Authorship 2185743Authorship 2187902Authorship 2193741Authorship 2197901Authorship 2208732Authorship 2227812Authorship 2239413Authorship 2248581Authorship 2254621Authorship 2279912Authorship 2317192Authorship 2326432Authorship 233237210784356Zhu Z, Li YL, Li DP, He RRPflugers Archiv : European journal of physiologyEffect of anoxic preconditioning on ATP-sensitive potassium channels in guinea-pig ventricular myocytes. Pflugers Arch. 2000 Apr; 439(6):808-13.Pflugers Arch2000-04-01T00:00:002000Effect of anoxic preconditioning on ATP-sensitive potassium channels in guinea-pig ventricular myocytes.11045993Li DP, Pan HLAmerican journal of physiology. Heart and circulatory physiologyResponses of neurons in rostral ventrolateral medulla to activation of cardiac receptors in rats. Am J Physiol Heart Circ Physiol. 2000 Nov; 279(5):H2549-57.Am J Physiol Heart Circ Physiol2000-11-01T00:00:002000Responses of neurons in rostral ventrolateral medulla to activation of cardiac receptors in rats.11367749Li DP, Fan ZZ, He RRSheng li xue bao : [Acta physiologica Sinica][Effects of endothelin on carotid baroreceptor activity in anesthetized rats]. Sheng Li Xue Bao. 1998 Oct; 50(5):532-8.Sheng Li Xue Bao1998-10-01T00:00:001998[Effects of endothelin on carotid baroreceptor activity in anesthetized rats].11498987Li DP, He RRSheng li xue bao : [Acta physiologica Sinica]Intracarotid injection of endothelin-1 facilitates the activity of rostral ventrolateral medullary neurons via area postrema in rats. Sheng Li Xue Bao. 1999 Jun; 51(3):263-71.Sheng Li Xue Bao1999-06-01T00:00:001999Intracarotid injection of endothelin-1 facilitates the activity of rostral ventrolateral medullary neurons via area postrema in rats.11507011Li DP, Averill DB, Pan HLAmerican journal of physiology. Regulatory, integrative and comparative physiologyDifferential roles for glutamate receptor subtypes within commissural NTS in cardiac-sympathetic reflex. Am J Physiol Regul Integr Comp Physiol. 2001 Sep; 281(3):R935-43.Am J Physiol Regul Integr Comp Physiol2001-09-01T00:00:002001Differential roles for glutamate receptor subtypes within commissural NTS in cardiac-sympathetic reflex.11749841Zhang YJ, Li DP, Xue BJ, Wang YL, He RRActa pharmacologica SinicaEffect of dipfluzine on L-type calcium current in guinea pig ventricular myocytes. Acta Pharmacol Sin. 2001 Aug; 22(8):701-5.Acta Pharmacol Sin2001-08-01T00:00:002001Effect of dipfluzine on L-type calcium current in guinea pig ventricular myocytes.11951114Chen S, Li DP, He RRSheng li xue bao : [Acta physiologica Sinica]Effects of microinjection of adenosine into area postrema on heart rate, blood pressure and renal sympathetic nerve activity in rats. Sheng Li Xue Bao. 2000 Aug; 52(4):313-7.Sheng Li Xue Bao2000-08-01T00:00:002000Effects of microinjection of adenosine into area postrema on heart rate, blood pressure and renal sympathetic nerve activity in rats.12231640Li DP, Chen SR, Pan YZ, Levey AI, Pan HLThe Journal of physiologyRole of presynaptic muscarinic and GABA(B) receptors in spinal glutamate release and cholinergic analgesia in rats. J Physiol. 2002 Sep 15; 543(Pt 3):807-18.J Physiol2002-09-15T00:00:002002Role of presynaptic muscarinic and GABA(B) receptors in spinal glutamate release and cholinergic analgesia in rats.14724227Finnegan TF, Li DP, Chen SR, Pan HLThe Journal of pharmacology and experimental therapeuticsActivation of mu-opioid receptors inhibits synaptic inputs to spinally projecting rostral ventromedial medulla neurons. J Pharmacol Exp Ther. 2004 May; 309(2):476-83.J Pharmacol Exp Ther2004-01-14T00:00:002004Activation of mu-opioid receptors inhibits synaptic inputs to spinally projecting rostral ventromedial medulla neurons.15640398Zhang HM, Li DP, Chen SR, Pan HLThe Journal of pharmacology and experimental therapeuticsM2, M3, and M4 receptor subtypes contribute to muscarinic potentiation of GABAergic inputs to spinal dorsal horn neurons. J Pharmacol Exp Ther. 2005 May; 313(2):697-704.J Pharmacol Exp Ther2005-01-07T00:00:002005M2, M3, and M4 receptor subtypes contribute to muscarinic potentiation of GABAergic inputs to spinal dorsal horn neurons.17537680Li DP, Yang QAutonomic neuroscience : basic & clinicalMembrane and synaptic properties of nucleus tractus solitarius neurons projecting to the caudal ventrolateral medulla. Auton Neurosci. 2007 Oct 30; 136(1-2):69-81.Auton Neurosci2007-05-29T00:00:002007Membrane and synaptic properties of nucleus tractus solitarius neurons projecting to the caudal ventrolateral medulla.17869444Yang Q, Chen SR, Li DP, Pan HLNeuroscienceKv1.1/1.2 channels are downstream effectors of nitric oxide on synaptic GABA release to preautonomic neurons in the paraventricular nucleus. Neuroscience. 2007 Oct 26; 149(2):315-27.Neuroscience2007-08-08T00:00:002007Kv1.1/1.2 channels are downstream effectors of nitric oxide on synaptic GABA release to preautonomic neurons in the paraventricular nucleus.18238817Li DP, Yang Q, Pan HM, Pan HLThe Journal of physiologyPre- and postsynaptic plasticity underlying augmented glutamatergic inputs to hypothalamic presympathetic neurons in spontaneously hypertensive rats. J Physiol. 2008 Mar 15; 586(6):1637-47.J Physiol2008-01-31T00:00:002008Pre- and postsynaptic plasticity underlying augmented glutamatergic inputs to hypothalamic presympathetic neurons in spontaneously hypertensive rats.19726694Sun H, Li DP, Chen SR, Hittelman WN, Pan HLThe Journal of pharmacology and experimental therapeuticsSensing of blood pressure increase by transient receptor potential vanilloid 1 receptors on baroreceptors. J Pharmacol Exp Ther. 2009 Dec; 331(3):851-9.J Pharmacol Exp Ther2009-09-02T00:00:002009Sensing of blood pressure increase by transient receptor potential vanilloid 1 receptors on baroreceptors.22723696Ye ZY, Li DP, Byun HS, Li L, Pan HLThe Journal of neuroscience : the official journal of the Society for NeuroscienceNKCC1 upregulation disrupts chloride homeostasis in the hypothalamus and increases neuronal activity-sympathetic drive in hypertension. J Neurosci. 2012 Jun 20; 32(25):8560-8.J Neurosci2012-06-20T00:00:002012NKCC1 upregulation disrupts chloride homeostasis in the hypothalamus and increases neuronal activity-sympathetic drive in hypertension.23647148Guo YX, Li DP, Chen SR, Pan HLJournal of neurochemistryDistinct intrinsic and synaptic properties of pre-sympathetic and pre-parasympathetic output neurons in Barrington's nucleus. J Neurochem. 2013 Aug; 126(3):338-48.J Neurochem2013-05-20T00:00:002013Distinct intrinsic and synaptic properties of pre-sympathetic and pre-parasympathetic output neurons in Barrington's nucleus.23716583Ye ZY, Li DP, Pan HLHypertension (Dallas, Tex. : 1979)Regulation of Hypothalamic Presympathetic Neurons and Sympathetic Outflow by Group II Metabotropic Glutamate Receptors in Spontaneously Hypertensive Rats. Hypertension. 2013 Aug; 62(2):255-62.Hypertension2013-05-28T00:00:002013Regulation of Hypothalamic Presympathetic Neurons and Sympathetic Outflow by Group II Metabotropic Glutamate Receptors in Spontaneously Hypertensive Rats.Authorship 2431112Authorship 2433541Authorship 2441571Authorship 2445132Authorship 2448491Authorship 2453501Authorship 2455133Authorship 2456702Authorship 2472351Authorship 2481052Authorship 2481121Authorship 2514272Authorship 2529401Authorship 2551602Authorship 2601147Authorship 2610801Authorship 261099111557616Li DP, Pan HLAmerican journal of physiology. Regulatory, integrative and comparative physiologyPotentiation of glutamatergic synaptic input to supraoptic neurons by presynaptic nicotinic receptors. Am J Physiol Regul Integr Comp Physiol. 2001 Oct; 281(4):R1105-13.Am J Physiol Regul Integr Comp Physiol2001-10-01T00:00:002001Potentiation of glutamatergic synaptic input to supraoptic neurons by presynaptic nicotinic receptors.11716821Li DP, Pan YZ, Pan HLBrain researchAcetylcholine attenuates synaptic GABA release to supraoptic neurons through presynaptic nicotinic receptors. Brain Res. 2001 Nov 30; 920(1-2):151-8.Brain Res2001-11-30T00:00:002001Acetylcholine attenuates synaptic GABA release to supraoptic neurons through presynaptic nicotinic receptors.11929913Pan YZ, Li DP, Pan HLJournal of neurophysiologyInhibition of glutamatergic synaptic input to spinal lamina II(o) neurons by presynaptic alpha(2)-adrenergic receptors. J Neurophysiol. 2002 Apr; 87(4):1938-47.J Neurophysiol2002-04-01T00:00:002002Inhibition of glutamatergic synaptic input to spinal lamina II(o) neurons by presynaptic alpha(2)-adrenergic receptors.12424302Li DP, Chen SR, Pan HLJournal of neurophysiologyNitric oxide inhibits spinally projecting paraventricular neurons through potentiation of presynaptic GABA release. J Neurophysiol. 2002 Nov; 88(5):2664-74.J Neurophysiol2002-11-01T00:00:002002Nitric oxide inhibits spinally projecting paraventricular neurons through potentiation of presynaptic GABA release.12829722Zahner MR, Li DP, Chen SR, Pan HLThe Journal of physiologyCardiac vanilloid receptor 1-expressing afferent nerves and their role in the cardiogenic sympathetic reflex in rats. J Physiol. 2003 Sep 01; 551(Pt 2):515-23.J Physiol2003-06-26T00:00:002003Cardiac vanilloid receptor 1-expressing afferent nerves and their role in the cardiogenic sympathetic reflex in rats.12832527Li DP, Chen SR, Pan HLThe Journal of neuroscience : the official journal of the Society for NeuroscienceAngiotensin II stimulates spinally projecting paraventricular neurons through presynaptic disinhibition. J Neurosci. 2003 Jun 15; 23(12):5041-9.J Neurosci2003-06-15T00:00:002003Angiotensin II stimulates spinally projecting paraventricular neurons through presynaptic disinhibition.14633560Logginidou HG, Li BH, Li DP, Lohmann JS, Schuler HG, DiVittore NA, Kreiser S, Cronin AJAnesthesia and analgesiaPropofol suppresses the cortical somatosensory evoked potential in rats. Anesth Analg. 2003 Dec; 97(6):1784-1788.Anesth Analg2003-12-01T00:00:002003Propofol suppresses the cortical somatosensory evoked potential in rats.14715151Pan YZ, Li DP, Chen SR, Pan HLBrain researchActivation of mu-opioid receptors excites a population of locus coeruleus-spinal neurons through presynaptic disinhibition. Brain Res. 2004 Jan 30; 997(1):67-78.Brain Res2004-01-30T00:00:002004Activation of mu-opioid receptors excites a population of locus coeruleus-spinal neurons through presynaptic disinhibition.15115794Li DP, Chen SR, Pan HLJournal of neurophysiologyVR1 receptor activation induces glutamate release and postsynaptic firing in the paraventricular nucleus. J Neurophysiol. 2004 Sep; 92(3):1807-16.J Neurophysiol2004-04-28T00:00:002004VR1 receptor activation induces glutamate release and postsynaptic firing in the paraventricular nucleus.17045312Zahner MR, Li DP, Pan HLNeuropharmacologyBenzodiazepine inhibits hypothalamic presympathetic neurons by potentiation of GABAergic synaptic input. Neuropharmacology. 2007 Feb; 52(2):467-75.Neuropharmacology2006-10-10T00:00:002006Benzodiazepine inhibits hypothalamic presympathetic neurons by potentiation of GABAergic synaptic input.17071818Li DP, Pan HLThe Journal of pharmacology and experimental therapeuticsRole of gamma-aminobutyric acid (GABA)A and GABAB receptors in paraventricular nucleus in control of sympathetic vasomotor tone in hypertension. J Pharmacol Exp Ther. 2007 Feb; 320(2):615-26.J Pharmacol Exp Ther2006-10-27T00:00:002006Role of gamma-aminobutyric acid (GABA)A and GABAB receptors in paraventricular nucleus in control of sympathetic vasomotor tone in hypertension.18222497Xing J, Li DP, Li JNeuropharmacologyRole of GABA receptors in nitric oxide inhibition of dorsolateral periaqueductal gray neurons. Neuropharmacology. 2008 Mar; 54(4):734-44.Neuropharmacology2008-01-28T00:00:002008Role of GABA receptors in nitric oxide inhibition of dorsolateral periaqueductal gray neurons.20096091Li DP, Chen SR, Pan HLJournal of neurochemistryAdenosine inhibits paraventricular pre-sympathetic neurons through ATP-dependent potassium channels. J Neurochem. 2010 Apr; 113(2):530-42.J Neurochem2010-01-25T00:00:002010Adenosine inhibits paraventricular pre-sympathetic neurons through ATP-dependent potassium channels.20937332Ye ZY, Li DPRegulatory peptidesActivation of the melanocortin-4 receptor causes enhanced excitation in presympathetic paraventricular neurons in obese Zucker rats. Regul Pept. 2011 Jan 17; 166(1-3):112-20.Regul Pept2010-10-16T00:00:002010Activation of the melanocortin-4 receptor causes enhanced excitation in presympathetic paraventricular neurons in obese Zucker rats.23656204Zhou JJ, Wei Y, Zhang L, Zhang J, Guo LY, Gao C, Li DP, Zhang YCanadian journal of physiology and pharmacologyChronic intermittent hypobaric hypoxia prevents cardiac dysfunction through enhancing antioxidation in fructose-fed rats. Can J Physiol Pharmacol. 2013 May; 91(5):332-7.Can J Physiol Pharmacol2013-01-15T00:00:002013Chronic intermittent hypobaric hypoxia prevents cardiac dysfunction through enhancing antioxidation in fructose-fed rats.24647951Li DP, Zhu LH, Pachuau J, Lee HA, Pan HLThe Journal of neuroscience : the official journal of the Society for NeurosciencemGluR5 Upregulation increases excitability of hypothalamic presympathetic neurons through NMDA receptor trafficking in spontaneously hypertensive rats. J Neurosci. 2014 Mar 19; 34(12):4309-17.J Neurosci2014-03-19T00:00:002014mGluR5 Upregulation increases excitability of hypothalamic presympathetic neurons through NMDA receptor trafficking in spontaneously hypertensive rats.24686191Li DP, Chen SRNeuroscience lettersNitric oxide stimulates glutamatergic synaptic inputs to baroreceptor neurons through potentiation of Cav2.2-mediated Ca(2+) currents. Neurosci Lett. 2014 May 01; 567:57-62.Neurosci Lett2014-03-28T00:00:002014Nitric oxide stimulates glutamatergic synaptic inputs to baroreceptor neurons through potentiation of Cav2.2-mediated Ca(2+) currents.Authorship 2658402Authorship 2668796Authorship 2677071Authorship 2695561Authorship 2697012Authorship 270022612438523Khan GM, Li DP, Chen SR, Pan HLThe Journal of pharmacology and experimental therapeuticsRole of spinal nitric oxide in the inhibitory effect of [D-Pen2, D-Pen5]-enkephalin on ascending dorsal horn neurons in normal and diabetic rats. J Pharmacol Exp Ther. 2002 Dec; 303(3):1021-8.J Pharmacol Exp Ther2002-12-01T00:00:002002Role of spinal nitric oxide in the inhibitory effect of [D-Pen2, D-Pen5]-enkephalin on ascending dorsal horn neurons in normal and diabetic rats.16243912Li DP, Pan HLAmerican journal of physiology. Heart and circulatory physiologyPlasticity of GABAergic control of hypothalamic presympathetic neurons in hypertension. Am J Physiol Heart Circ Physiol. 2006 Mar; 290(3):H1110-9.Am J Physiol Heart Circ Physiol2005-10-21T00:00:002005Plasticity of GABAergic control of hypothalamic presympathetic neurons in hypertension.17959251Pan HL, Wu ZZ, Zhou HY, Chen SR, Zhang HM, Li DPPharmacology & therapeuticsModulation of pain transmission by G-protein-coupled receptors. Pharmacol Ther. 2008 Jan; 117(1):141-61.Pharmacol Ther2007-09-22T00:00:002007Modulation of pain transmission by G-protein-coupled receptors.20655486Li DP, Pan HLAdvances in pharmacology (San Diego, Calif.)Role of GABAB receptors in autonomic control of systemic blood pressure. Adv Pharmacol. 2010; 58:257-86.Adv Pharmacol2010-01-01T00:00:002010Role of GABAB receptors in autonomic control of systemic blood pressure.21632948Ye ZY, Li DP, Li L, Pan HLThe Journal of neuroscience : the official journal of the Society for NeuroscienceProtein kinase CK2 increases glutamatergic input in the hypothalamus and sympathetic vasomotor tone in hypertension. J Neurosci. 2011 Jun 01; 31(22):8271-9.J Neurosci2011-06-01T00:00:002011Protein kinase CK2 increases glutamatergic input in the hypothalamus and sympathetic vasomotor tone in hypertension.22173869Li Q, Ma HJ, Song SL, Shi M, Ma HJ, Li DP, Zhang YAmerican journal of physiology. Cell physiologyEffects of anandamide on potassium channels in rat ventricular myocytes: a suppression of I(to) and augmentation of K(ATP) channels. Am J Physiol Cell Physiol. 2012 Mar 15; 302(6):C924-30.Am J Physiol Cell Physiol2011-12-14T00:00:002011Effects of anandamide on potassium channels in rat ventricular myocytes: a suppression of I(to) and augmentation of K(ATP) channels.Authorship 2733111Authorship 2741581Authorship 276974111324531Li DP, Fan ZZ, He RRSheng li xue bao : [Acta physiologica Sinica][Modulatory effects of endothelin on carotid baroreflex in anesthetized rats]. Sheng Li Xue Bao. 1998 Apr; 50(2):169-75.Sheng Li Xue Bao1998-04-01T00:00:001998[Modulatory effects of endothelin on carotid baroreflex in anesthetized rats].17309953Li DP, Pan HLHypertension (Dallas, Tex. : 1979)Glutamatergic inputs in the hypothalamic paraventricular nucleus maintain sympathetic vasomotor tone in hypertension. Hypertension. 2007 Apr; 49(4):916-25.Hypertension2007-02-19T00:00:002007Glutamatergic inputs in the hypothalamic paraventricular nucleus maintain sympathetic vasomotor tone in hypertension.20519363Li DP, Pan HLAmerican journal of physiology. Regulatory, integrative and comparative physiologyIncreased group I metabotropic glutamate receptor activity in paraventricular nucleus supports elevated sympathetic vasomotor tone in hypertension. Am J Physiol Regul Integr Comp Physiol. 2010 Aug; 299(2):R552-61.Am J Physiol Regul Integr Comp Physiol2010-06-02T00:00:002010Increased group I metabotropic glutamate receptor activity in paraventricular nucleus supports elevated sympathetic vasomotor tone in hypertension.25267719Li L, Li DP, Chen SR, Chen J, Hu H, Pan HLMolecular pharmacologyPotentiation of high voltage-activated calcium channels by 4-aminopyridine depends on subunit composition. Mol Pharmacol. 2014 Dec; 86(6):760-72.Mol Pharmacol2014-09-29T00:00:002014Potentiation of high voltage-activated calcium channels by 4-aminopyridine depends on subunit composition.74Professor14Associate Professor46Distinguished Emeritus Professor47Distinguished Service Professor53Graduate StudentAuthorship 3744342Authorship 846896Authorship 847457Authorship 848501Authorship 853011Authorship 856863Authorship 857185Authorship 859456Authorship 860099Authorship 860112Authorship 861247Authorship 866155Authorship 866508NeuropharmacologyUpregulation of orexin receptor in paraventricular nucleus promotes sympathetic outflow in obese Zucker rats. Neuropharmacology. 99:481-490.Upregulation of orexin receptor in paraventricular nucleus promotes sympathetic outflow in obese Zucker ratsHypertensionResponse to glutamate receptors and presympathetic neuronal hyperactivity of the central nervous system in hypertension. Hypertension. 62.Response to glutamate receptors and presympathetic neuronal hyperactivity of the central nervous system in hypertensionJournal of PhysiologyEndogenous casein kinase-1 modulates NMDA receptor activity of hypothalamic presympathetic neurons and sympathetic outflow in hypertension. Journal of Physiology. 593:4439-4452.Endogenous casein kinase-1 modulates NMDA receptor activity of hypothalamic presympathetic neurons and sympathetic outflow in hypertensionPLoS OneCorrection. PLoS One. 8.CorrectionNeuroendocrinologyChronic Unpredictable Mild Stress Induces Loss of GABA Inhibition in Corticotrophin-Releasing Hormone-Expressing Neurons Through NKCC1 Upregulation. Neuroendocrinology. Chronic Unpredictable Mild Stress Induces Loss of GABA Inhibition in Corticotrophin-Releasing Hormone-Expressing Neurons Through NKCC1 UpregulationNature NeuroscienceG9a is essential for epigenetic silencing of K<sup>+</sup> channel genes in acute-to-chronic pain transition. Nature Neuroscience. G9a is essential for epigenetic silencing of K<sup>+</sup> channel genes in acute-to-chronic pain transitionJournal of Inflammation (United Kingdom)The protective effects of chronic intermittent hypobaric hypoxia pretreatment against collagen-induced arthritis in rats. Journal of Inflammation (United Kingdom). 12.The protective effects of chronic intermittent hypobaric hypoxia pretreatment against collagen-induced arthritis in ratsNeuropharmacologyAcute stress diminishes M-current contributing to elevated activity of hypothalamic-pituitary-adrenal axis. Neuropharmacology. 114:67-76.Acute stress diminishes M-current contributing to elevated activity of hypothalamic-pituitary-adrenal axisJournal of NeuroscienceGabaergic projections from lateral hypothalamus to paraventricular hypothalamic nucleus promote feeding. Journal of Neuroscience. 35:3312-3318.Gabaergic projections from lateral hypothalamus to paraventricular hypothalamic nucleus promote feedingHypertensionSrc Kinases Regulate Glutamatergic Input to Hypothalamic Presympathetic Neurons and Sympathetic Outflow in Hypertension. Hypertension. 69:154-162.Src Kinases Regulate Glutamatergic Input to Hypothalamic Presympathetic Neurons and Sympathetic Outflow in HypertensionAmerican Journal of PhysiologyPotentiation of glutamatergic synaptic input to supraoptic neurons by presynaptic nicotinic receptors. American Journal of Physiology. 281.Potentiation of glutamatergic synaptic input to supraoptic neurons by presynaptic nicotinic receptorsPlastic and Reconstructive SurgeryPeripheral motor and sensory nerve conduction following transplantation of undifferentiated autologous adipose tissue-derived stem cells in a biodegradable U.S. food and drug administration-approved nerve conduit. Plastic and Reconstructive Surgery. 138:132-139.Peripheral motor and sensory nerve conduction following transplantation of undifferentiated autologous adipose tissue-derived stem cells in a biodegradable U.S. food and drug administration-approved nerve conduit22829581Guan X, Shi X, Li X, Chang B, Wang Y, Li D, Chan LAmerican journal of physiology. Endocrinology and metabolismGLP-2 receptor in POMC neurons suppresses feeding behavior and gastric motility. Am J Physiol Endocrinol Metab. 2012 Oct 01; 303(7):E853-64.Am J Physiol Endocrinol Metab2012-07-24T00:00:002012GLP-2 receptor in POMC neurons suppresses feeding behavior and gastric motility.true1Distinguished Service ProfessorDistinguished Service ProfessorD009474Anatomy61422850.451917NeuronsD013569Anatomy1765130.718689SynapsesD010286Anatomy271250.880896Paraventricular Hypothalamic NucleusD006973Disorders51714880.496413HypertensionD013564Anatomy731600.897376Sympathetic Nervous SystemAuthorship 918456128972129Li DP, Zhou JJ, Zhang J, Pan HLThe Journal of neuroscience : the official journal of the Society for NeuroscienceCaMKII Regulates Synaptic NMDA Receptor Activity of Hypothalamic Presympathetic Neurons and Sympathetic Outflow in Hypertension. J Neurosci. 2017 11 01; 37(44):10690-10699.J Neurosci2017-10-02T00:00:002017CaMKII Regulates Synaptic NMDA Receptor Activity of Hypothalamic Presympathetic Neurons and Sympathetic Outflow in Hypertension.Department of MedicineDepartment of PediatricsMedicine-EndocrinologyPediatrics-NeurologyPediatrics-NutritionBaylor College of MedicineHUDAZOGHBIHUDA ZOGHBI29.71010310000000-95.397396100000002830ZOGHBI, HUDADistinguished Service ProfessorYONGXUYONG XU0.000000000000000.000000000000001730XU, YONGProfessorLAWRENCECHANLAWRENCE CHAN0.000000000000000.000000000000002285CHAN, LAWRENCEDistinguished Emeritus Professor23823479Shi X, Zhou F, Li X, Chang B, Li D, Wang Y, Tong Q, Xu Y, Fukuda M, Zhao JJ, Li D, Burrin DG, Chan L, Guan XCell metabolismCentral GLP-2 enhances hepatic insulin sensitivity via activating PI3K signaling in POMC neurons. Cell Metab. 2013 Jul 02; 18(1):86-98.Cell Metab2013-07-02T00:00:002013Central GLP-2 enhances hepatic insulin sensitivity via activating PI3K signaling in POMC neurons.Development, Disease Models & Therapeuticstrue1Graduate StudentGraduate StudentJingZhouJing Zhou15839Zhou, JingGraduate Studenttrue1ProfessorProfessortrue1Distinguished Emeritus ProfessorDistinguished Emeritus Professortrue1ProfessorProfessortrue1ProfessorProfessortrue1Associate ProfessorAssociate Professortrue1Associate ProfessorAssociate Professor25189211Qi Y, Wang J, Bomben VC, Li DP, Chen SR, Sun H, Xi Y, Reed JG, Cheng J, Pan HL, Noebels JL, Yeh ETNeuronHyper-SUMOylation of the Kv7 potassium channel diminishes the M-current leading to seizures and sudden death. Neuron. 2014 Sep 03; 83(5):1159-71.Neuron2014-09-03T00:00:002014Hyper-SUMOylation of the Kv7 potassium channel diminishes the M-current leading to seizures and sudden death.