SOUNG-CHULCHASOUNG-CHUL CHA9160CHA, SOUNG-CHULAssistant Professorprns:coAuthorOfcoauthor ofFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressvivo:address1address line 1vivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provincevivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentDivisionvivo:hasResearchArearesearch areasvivo:hrJobTitleHR job titleInformation Resourcevivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:personInPositionpositionsPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPerson7455 Fannin StHouston77054-1901TXAuthorship 1767635Authorship 1767984Authorship 1858736Authorship 188072216793161Pai Kasturi S, Qin H, Thomson KS, El-Bereir S, Cha SC, Neelapu S, Kwak LW, Roy KJournal of controlled release : official journal of the Controlled Release SocietyProphylactic anti-tumor effects in a B cell lymphoma model with DNA vaccines delivered on polyethylenimine (PEI) functionalized PLGA microparticles. J Control Release. 2006 Jul 20; 113(3):261-70.J Control Release2006-05-03T00:00:002006Prophylactic anti-tumor effects in a B cell lymphoma model with DNA vaccines delivered on polyethylenimine (PEI) functionalized PLGA microparticles.16827622Neelapu SS, Lee ST, Qin H, Cha SC, Woo AF, Kwak LWExpert review of vaccinesTherapeutic lymphoma vaccines: importance of T-cell immunity. Expert Rev Vaccines. 2006 Jun; 5(3):381-94.Expert Rev Vaccines2006-06-01T00:00:002006Therapeutic lymphoma vaccines: importance of T-cell immunity.20454526Qin H, Nehete PN, He H, Nehete B, Buchl S, Cha SC, Sastry JK, Kwak LWJournal of biomedicine & biotechnologyPrime-boost vaccination using chemokine-fused gp120 DNA and HIV envelope peptides activates both immediate and long-term memory cellular responses in rhesus macaques. J Biomed Biotechnol. 2010; 2010:860160.J Biomed Biotechnol2010-05-05T00:00:002010Prime-boost vaccination using chemokine-fused gp120 DNA and HIV envelope peptides activates both immediate and long-term memory cellular responses in rhesus macaques.21813633Weng J, Cha SC, Matsueda S, Alatrash G, Popescu MS, Yi Q, Molldrem JJ, Wang M, Neelapu SS, Kwak LWClinical cancer research : an official journal of the American Association for Cancer ResearchTargeting human B-cell malignancies through Ig light chain-specific cytotoxic T lymphocytes. Clin Cancer Res. 2011 Sep 15; 17(18):5945-52.Clin Cancer Res2011-08-03T00:00:002011Targeting human B-cell malignancies through Ig light chain-specific cytotoxic T lymphocytes.HematopathologyLeukemiaLymphoma-MyelomaMelanoma Medical OncologyStem Cell TransplantationMD AndersonWILLEMOVERWIJKWILLEM OVERWIJK9188OVERWIJK, WILLEMProfessorHAGOP MKANTARJIANHAGOP M KANTARJIAN8501KANTARJIAN, HAGOP MProfessorSATTVA SNEELAPUSATTVA S NEELAPU9154NEELAPU, SATTVA SAssociate ProfessorELIZABETH ANNMITTENDORFELIZABETH ANN MITTENDORF9277MITTENDORF, ELIZABETH ANNAssociate ProfessorL JEFFREYMEDEIROSL JEFFREY MEDEIROS8762MEDEIROS, L JEFFREYProfessorJINSHENGWENGJINSHENG WENG9546WENG, JINSHENGInstructorSHEEBA KOSHYTHOMASSHEEBA KOSHY THOMAS9017THOMAS, SHEEBA KOSHYAssociate ProfessorMUZAFFAR HQAZILBASHMUZAFFAR H QAZILBASH9055QAZILBASH, MUZAFFAR HProfessor0.8916170.00651358159research areas1.133290.019864522coauthor of15.44433.1863560similar to1132selected publicationsAuthorship 2206045Authorship 2253983Authorship 2281652Authorship 228974315075363Ruffini PA, Biragyn A, Coscia M, Harvey LK, Cha SC, Bogen B, Kwak LWJournal of leukocyte biologyGenetic fusions with viral chemokines target delivery of nonimmunogenic antigen to trigger antitumor immunity independent of chemotaxis. J Leukoc Biol. 2004 Jul; 76(1):77-85.J Leukoc Biol2004-04-09T00:00:002004Genetic fusions with viral chemokines target delivery of nonimmunogenic antigen to trigger antitumor immunity independent of chemotaxis.17933439Zhu K, Qin H, Cha SC, Neelapu SS, Overwijk W, Lizee GA, Abbruzzese JL, Hwu P, Radvanyi L, Kwak LW, Chang DZVaccineSurvivin DNA vaccine generated specific antitumor effects in pancreatic carcinoma and lymphoma mouse models. Vaccine. 2007 Nov 14; 25(46):7955-61.Vaccine2007-09-14T00:00:002007Survivin DNA vaccine generated specific antitumor effects in pancreatic carcinoma and lymphoma mouse models.20937320Qin H, Cha SC, Neelapu SS, Liu C, Wang YH, Wei J, Qin XF, Liu YJ, Kwak LWVaccineGeneration of an immune microenvironment as a novel mechanism for myotoxins to potentiate genetic vaccines. Vaccine. 2010 Nov 23; 28(50):7970-8.Vaccine2010-11-23T00:00:002010Generation of an immune microenvironment as a novel mechanism for myotoxins to potentiate genetic vaccines.21382485Park HJ, Qin H, Cha SC, Sharma R, Chung Y, Schluns KS, Neelapu SS, Overwijk WW, Hwu P, Kwak LWVaccineInduction of TLR4-dependent CD8+ T cell immunity by murine ?-defensin2 fusion protein vaccines. Vaccine. 2011 Apr 18; 29(18):3476-82.Vaccine2011-03-05T00:00:002011Induction of TLR4-dependent CD8+ T cell immunity by murine ?-defensin2 fusion protein vaccines.Authorship 2479442Authorship 262400516966263Kobrin C, Cha SC, Qin H, Raffeld M, Fend F, Quintanilla-Martinez L, Grove S, Jaffe ES, Kwak LWLeukemia & lymphomaMolecular analysis of light-chain switch and acute lymphoblastic leukemia transformation in two follicular lymphomas: implications for lymphomagenesis. Leuk Lymphoma. 2006 Aug; 47(8):1523-34.Leuk Lymphoma2006-08-01T00:00:002006Molecular analysis of light-chain switch and acute lymphoblastic leukemia transformation in two follicular lymphomas: implications for lymphomagenesis.24619688Cha SC, Qin H, Sakamaki I, Kwak LMethods in molecular biology (Clifton, N.J.)Cloning variable region genes of clonal lymphoma immunoglobulin for generating patient-specific idiotype DNA vaccine. Methods Mol Biol. 2014; 1139:289-303.Methods Mol Biol2014-01-01T00:00:002014Cloning variable region genes of clonal lymphoma immunoglobulin for generating patient-specific idiotype DNA vaccine.24859530Qin H, Lerman B, Sakamaki I, Wei G, Cha SC, Rao SS, Qian J, Hailemichael Y, Nurieva R, Dwyer KC, Roth J, Yi Q, Overwijk WW, Kwak LWNature medicineGeneration of a new therapeutic peptide that depletes myeloid-derived suppressor cells in tumor-bearing mice. Nat Med. 2014 Jun; 20(6):676-81.Nat Med2014-05-25T00:00:002014Generation of a new therapeutic peptide that depletes myeloid-derived suppressor cells in tumor-bearing mice.Authorship 2694262Authorship 271293319749091Qin H, Cha SC, Neelapu SS, Lou Y, Wei J, Liu YJ, Kwak LWBloodVaccine site inflammation potentiates idiotype DNA vaccine-induced therapeutic T cell-, and not B cell-, dependent antilymphoma immunity. Blood. 2009 Nov 05; 114(19):4142-9.Blood2009-09-11T00:00:002009Vaccine site inflammation potentiates idiotype DNA vaccine-induced therapeutic T cell-, and not B cell-, dependent antilymphoma immunity.23765229Sakamaki I, Kwak LW, Cha SC, Yi Q, Lerman B, Chen J, Surapaneni S, Bateman S, Qin HLeukemiaLenalidomide enhances the protective effect of a therapeutic vaccine and reverses immune suppression in mice bearing established lymphomas. Leukemia. 2014 Feb; 28(2):329-37.Leukemia2013-06-14T00:00:002013Lenalidomide enhances the protective effect of a therapeutic vaccine and reverses immune suppression in mice bearing established lymphomas.Authorship 2729081Authorship 274807116631194Cha SC, Kwak LW, Ruffini PA, Qin H, Neelapu S, Biragyn AJournal of immunological methodsCloning of B cell lymphoma-associated antigens using modified phage-displayed expression cDNA library and immunized patient sera. J Immunol Methods. 2006 May 30; 312(1-2):79-93.J Immunol Methods2006-03-31T00:00:002006Cloning of B cell lymphoma-associated antigens using modified phage-displayed expression cDNA library and immunized patient sera.23536634Cha SC, Qin H, Kannan S, Rawal S, Watkins LS, Baio FE, Wu W, Ong J, Wei J, Kwak B, Kim S, Popescu MS, Paick DS, Kim K, Luong A, Davis RE, Schroeder HW, Kwak LW, Neelapu SSJournal of immunology (Baltimore, Md. : 1950)Nonstereotyped lymphoma B cell receptors recognize vimentin as a shared autoantigen. J Immunol. 2013 May 01; 190(9):4887-98.J Immunol2013-03-27T00:00:002013Nonstereotyped lymphoma B cell receptors recognize vimentin as a shared autoantigen.Authorship 279245174Professor10Assistant Professor54Instructor14Associate ProfessorBreast Surgical OncologyAuthorship 841225Authorship 841990Authorship 855244Authorship 855359Authorship 856995Authorship 865713Authorship 866922Journal of Microbiology and BiotechnologyExpression of the HSV-1 (F) glycoprotein B gene in insect cells infected by HcNPV recombinant. Journal of Microbiology and Biotechnology. 10:355-362.Expression of the HSV-1 (F) glycoprotein B gene in insect cells infected by HcNPV recombinantJournal of MicrobiologyOverexpression of insecticidal protein gene of Bacillus thuringiensis var. kurstaki HD1. Journal of Microbiology. 36:289-295.Overexpression of insecticidal protein gene of Bacillus thuringiensis var. kurstaki HD1Journal of Biochemistry and Molecular BiologyHigh Level Production of Glycoprotein H of HSV-1 (F) Using HcNPV Vector System. Journal of Biochemistry and Molecular Biology. 33:483-492.High Level Production of Glycoprotein H of HSV-1 (F) Using HcNPV Vector SystemOncoImmunologyTargeting B-cell malignancies through human B-cell receptor specific CD4<sup>+</sup> T cells. OncoImmunology. 5.Targeting B-cell malignancies through human B-cell receptor specific CD4<sup>+</sup> T cellsJournal of Microbiology and BiotechnologyConstruction of a baculovirus expression system using Hyphantria cunea nuclear polyhedrosis virus for eukaryotic cells. Journal of Microbiology and Biotechnology. 8:676-684.Construction of a baculovirus expression system using Hyphantria cunea nuclear polyhedrosis virus for eukaryotic cellsJournal of Microbiology and BiotechnologyConstruction of a baculovirus Hyphantria cunea NPV insecticide containing the insecticidal protein gene of Bacillus thuringiensis subsp. kurstaki HD1. Journal of Microbiology and Biotechnology. 8:685-691.Construction of a baculovirus Hyphantria cunea NPV insecticide containing the insecticidal protein gene of Bacillus thuringiensis subsp. kurstaki HD1Korean Journal of Applied Microbiology and BiotechnologyExpression in Escherichia coli of a cloned Bacillus thuringiensis subsp. kurstaki HD1 insecticidal protein gene. Korean Journal of Applied Microbiology and Biotechnology. 26:497-506.Expression in Escherichia coli of a cloned Bacillus thuringiensis subsp. kurstaki HD1 insecticidal protein geneD019444Chemicals & Drugs541050.921856Vaccines, DNAD016393Disorders2788930.596076Lymphoma, B-CellD008223Disorders49414640.526032LymphomaD019496Chemicals & Drugs2336960.647037Cancer VaccinesD007130Chemicals & Drugs26510.979603Immunoglobulin IdiotypesAuthorship 91315510Authorship 9239522Authorship 92498710Authorship 925126727999743Weng J, Baio FE, Moriarty KE, Torikai H, Wang H, Liu Z, Maiti SN, Gwak D, Popescu MS, Cha SC, Cooper LJ, Neelapu SS, Kwak LWOncoimmunologyTargeting B-cell malignancies through human B-cell receptor specific CD4+ T cells. Oncoimmunology. 2016; 5(11):e1232220.Oncoimmunology2016-09-19T00:00:002016Targeting B-cell malignancies through human B-cell receptor specific CD4+ T cells.29180606Qin H, Wei G, Sakamaki I, Dong Z, Cheng WA, Smith DL, Wen F, Sun H, Kim K, Cha S, Bover L, Neelapu SS, Kwak LWClinical cancer research : an official journal of the American Association for Cancer ResearchNovel BAFF-Receptor Antibody to Natively Folded Recombinant Protein Eliminates Drug-Resistant Human B-cell Malignancies In Vivo. Clin Cancer Res. 2018 03 01; 24(5):1114-1123.Clin Cancer Res2017-11-27T00:00:002017Novel BAFF-Receptor Antibody to Natively Folded Recombinant Protein Eliminates Drug-Resistant Human B-cell Malignancies In Vivo.29855694Liu Y, Wei G, Cheng WA, Dong Z, Sun H, Lee VY, Cha SC, Smith DL, Kwak LW, Qin HCancer immunology, immunotherapy : CIITargeting myeloid-derived suppressor cells for cancer immunotherapy. Cancer Immunol Immunother. 2018 Aug; 67(8):1181-1195.Cancer Immunol Immunother2018-05-31T00:00:002018Targeting myeloid-derived suppressor cells for cancer immunotherapy.29439670Thomas SK, Cha SC, Smith DL, Kim KH, Parshottam SR, Rao S, Popescu M, Lee VY, Neelapu SS, Kwak LWBMC cancerPhase I study of an active immunotherapy for asymptomatic phase Lymphoplasmacytic lymphoma with DNA vaccines encoding antigen-chemokine fusion: study protocol. BMC Cancer. 2018 02 13; 18(1):187.BMC Cancer2018-02-13T00:00:002018Phase I study of an active immunotherapy for asymptomatic phase Lymphoplasmacytic lymphoma with DNA vaccines encoding antigen-chemokine fusion: study protocol.Department of MedicineMedicine-General MedicineBaylor College of Medicine33178829Qin H, Nehete PN, He H, Nehete B, Buchl S, Cha SC, Sastry JK, Kwak LWBioMed research internationalCorrigendum to "Prime-Boost Vaccination Using Chemokine-Fused gp120 DNA and HIV Envelope Peptides Activates Both Immediate and Long-Term Memory Cellular Responses in Rhesus Macaques". Biomed Res Int. 2020; 2020:5471638.Biomed Res Int2020-10-29T00:00:002020Corrigendum to "Prime-Boost Vaccination Using Chemokine-Fused gp120 DNA and HIV Envelope Peptides Activates Both Immediate and Long-Term Memory Cellular Responses in Rhesus Macaques".34521108Qazilbash MH, Saini NY, Cha SC, Wang Z, Stadtmauer EA, Baladandayuthapani V, Lin H, Tross B, Honhar M, Rao SS, Kim K, Popescu M, Szymura S, Zhang T, Anderson A, Bashir Q, Shpall EJ, Orlowski RZ, Levine BL, Kerr N, Garfall A, Cohen A, Vogl DT, Dengel K, June CH, Champlin R, Kwak LWBloodA randomized phase 2 trial of idiotype vaccination and adoptive autologous T-cell transfer in patients with multiple myeloma. Blood. 2022 03 03; 139(9):1289-1301.Blood2022-03-03T00:00:002022A randomized phase 2 trial of idiotype vaccination and adoptive autologous T-cell transfer in patients with multiple myeloma.Authorship 10377603Authorship 1040065735039637Wang X, Dong Z, Awuah D, Chang WC, Cheng WA, Vyas V, Cha SC, Anderson AJ, Zhang T, Wang Z, Szymura SJ, Kuang BZ, Clark MC, Aldoss I, Forman SJ, Kwak LW, Qin HLeukemiaCD19/BAFF-R dual-targeted CAR T cells for the treatment of mixed antigen-negative variants of acute lymphoblastic leukemia. Leukemia. 2022 04; 36(4):1015-1024.Leukemia2022-01-18T00:00:002022CD19/BAFF-R dual-targeted CAR T cells for the treatment of mixed antigen-negative variants of acute lymphoblastic leukemia.Authorship 10484116JORGECASTILLOJORGE CASTILLO18140CASTILLO, JORGEAssistant Professortrue1Assistant ProfessorAssistant ProfessorAuthorship 10657831836469551Dong Z, Song JY, Thieme E, Anderson A, Oh E, Cheng WA, Kuang BZ, Lee V, Zhang T, Wang Z, Szymura S, Smith DL, Zhang J, Nian W, Zheng X, He F, Zhou Q, Cha SC, Danilov AV, Qin H, Kwak LWBlood advancesGeneration of a humanized afucosylated BAFF-R antibody with?broad activity against human B-cell malignancies. Blood Adv. 2023 03 28; 7(6):918-932.Blood Adv2023-03-28T00:00:002023Generation of a humanized afucosylated BAFF-R antibody with?broad activity against human B-cell malignancies.Authorship 10669111236979775Wang Z, Zhang T, Anderson A, Lee V, Szymura S, Dong Z, Kuang B, Oh E, Liu J, Neelapu SS, Kwak L, Cha SCBiomedicinesImmortalized B Cells Transfected with mRNA of Antigen Fused to MITD (IBMAM): An Effective Tool for Antigen-Specific T-Cell Expansion and TCR Validation. Biomedicines. 2023 Mar 06; 11(3).Biomedicines2023-03-06T00:00:002023Immortalized B Cells Transfected with mRNA of Antigen Fused to MITD (IBMAM): An Effective Tool for Antigen-Specific T-Cell Expansion and TCR Validation.Authorship 1080352537790486Kwak L, Szymura S, Wang L, Zhang T, Cha SC, Dong Z, Anderson A, Oh E, Lee V, Wang Z, Parshottham S, Rao S, Olsem J, Crumpton B, Lee H, Manasanch E, Neelapu S, Thomas SResearch squareFirst-in-human clinical trial of personalized neoantigen vaccines as early intervention in untreated patients with lymphoplasmacytic lymphoma. Res Sq. 2023 Sep 21.Res Sq2023-09-21T00:00:002023First-in-human clinical trial of personalized neoantigen vaccines as early intervention in untreated patients with lymphoplasmacytic lymphoma.true1Associate ProfessorAssociate Professortrue1InstructorInstructortrue1Associate ProfessorAssociate Professortrue1Assistant ProfessorAssistant Professortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1Associate ProfessorAssociate Professor