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FERNANDO MARTINEZ

TitleAssistant Professor
InstitutionMD Anderson
DepartmentLaboratory Medicine
Address2555 Holly Hall
Houston TX 77054-4124
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    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Park N, Correa Medina M, Martinez F, Throssel M, Dasgupta A, Knopfelmacher A, Villamin C, Rivas S, Tomczak N, Garg S, Layton L, Klein K. Trend towards reduction of transfusion reactions using prestorage leukocyte-reduced and pooled whole blood-derived platelets and cost savings compared with poststorage whole blood-derived random platelets as evidenced by real-time hemovigilance. Lab Med. 2024 May 02; 55(3):251-254. PMID: 38175635.
      Citations:    Fields:    Translation:HumansPHPublic Health
    2. Martinez F, Castillo E, Griffin G, Chapman S, Dey M, Tholpady A, Kelley J, Klein K, Dasgupta A, Correa-Medina M, Lichtiger B. Technical Note: Use of a Novel Bacterial Culture Sampling Device for Pooled Whole Blood Platelets. Ann Clin Lab Sci. 2023 May; 53(3):485-488. PMID: 37437944.
      Citations:    Fields:    Translation:HumansCells
    3. Kato T, Asakura T, Edwards CE, Dang H, Mikami Y, Okuda K, Chen G, Sun L, Gilmore RC, Hawkins P, De la Cruz G, Cooley MR, Bailey AB, Hewitt SM, Chertow DS, Borczuk AC, Salvatore S, Martinez FJ, Thorne LB, Askin FB, Ehre C, Randell SH, O'Neal WK, Baric RS, Boucher RC. Prevalence and Mechanisms of Mucus Accumulation in COVID-19 Lung Disease. Am J Respir Crit Care Med. 2022 12 01; 206(11):1336-1352. PMID: 35816430; PMCID: PMC9746856.
      Citations:    Fields:    
    4. Halpin DMG, Martinez FJ. Pharmacotherapy and Mortality in Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2022 11 15; 206(10):1201-1207. PMID: 35901121.
      Citations:    Fields:    
    5. Raghu G, Mouded M, Chambers DC, Martinez FJ, Lancaster LH, Hamblin MJ, Gibson KF, Rosas IO, Prasse A, Zhao G, Serenko M, Novikov N, McCurley A, Bansal P, Stebbins C, Arefayene M, Ibebunjo S, Violette SM, Gallagher D, Richeldi L, Behr J. A Phase IIb Randomized Clinical Study of an Anti-av?6 Monoclonal Antibody in Idiopathic Pulmonary Fibrosis. Am J Respir Crit Care Med. 2022 11 01; 206(9):1128-1139. PMID: 35771569.
      Citations:    Fields:    
    6. Krishnan JK, Rajan M, Banerjee S, Mallya SG, Han MK, Mannino DM, Martinez FJ, Safford MM. Race and Sex Differences in Mortality in Individuals with Chronic Obstructive Pulmonary Disease. Ann Am Thorac Soc. 2022 10; 19(10):1661-1668. PMID: 35657680; PMCID: PMC9528745.
      Citations:    Fields:    
    7. Han MK, Ye W, Wang D, White E, Arjomandi M, Barjaktarevic IZ, Brown SA, Buhr RG, Comellas AP, Cooper CB, Criner GJ, Dransfield MT, Drescher F, Folz RJ, Hansel NN, Kalhan R, Kaner RJ, Kanner RE, Krishnan JA, Lazarus SC, Maddipati V, Martinez FJ, Mathews A, Meldrum C, McEvoy C, Nyunoya T, Rogers L, Stringer WW, Wendt CH, Wise RA, Wisniewski SR, Sciurba FC, Woodruff PG, RETHINC Study Group. Bronchodilators in Tobacco-Exposed Persons with Symptoms and Preserved Lung Function. N Engl J Med. 2022 09 29; 387(13):1173-1184. PMID: 36066078; PMCID: PMC9741866.
      Citations:    
    8. Buhr RG, Barjaktarevic IZ, Quibrera PM, Bateman LA, Bleecker ER, Couper DJ, Curtis JL, Dolezal BA, Han MK, Hansel NN, Krishnan JA, Martinez FJ, McKleroy W, Paine R, Rennard SI, Tashkin DP, Woodruff PG, Kanner RE, Cooper CB, SPIROMICS Investigators. Reversible Airflow Obstruction Predicts Future Chronic Obstructive Pulmonary Disease Development in the SPIROMICS Cohort: An Observational Cohort Study. Am J Respir Crit Care Med. 2022 09 01; 206(5):554-562. PMID: 35549640; PMCID: PMC9716898.
      Citations:    Fields:    
    9. Madapoosi SS, Cruickshank-Quinn C, Opron K, Erb-Downward JR, Begley LA, Li G, Barjaktarevic I, Barr RG, Comellas AP, Couper DJ, Cooper CB, Freeman CM, Han MK, Kaner RJ, Labaki W, Martinez FJ, Ortega VE, Peters SP, Paine R, Woodruff P, Curtis JL, Huffnagle GB, Stringer KA, Bowler RP, Esther CR, Reisdorph N, Huang YJ, SPIROMICS Research Group. Lung Microbiota and Metabolites Collectively Associate with Clinical Outcomes in Milder Stage Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2022 08 15; 206(4):427-439. PMID: 35536732; PMCID: PMC11418810.
      Citations:    Fields:    
    10. Baugh A, Buhr RG, Quibrera P, Barjaktarevic I, Barr RG, Bowler R, Han MK, Kaufman JD, Koch AL, Krishnan J, Labaki W, Martinez FJ, Mkorombindo T, Namen A, Ortega V, Paine R, Peters SP, Schotland H, Sundar K, Zeidler MR, Hansel NN, Woodruff PG, Thakur N. Risk of COPD exacerbation is increased by poor sleep quality and modified by social adversity. Sleep. 2022 08 11; 45(8). PMID: 35665826; PMCID: PMC9366643.
      Citations:    Fields:    
    11. Criner GJ, Borghaei H, Friedberg J, Martinez FJ, Miyamoto C, Vogelmeier CF, Celli BR, Agusti A. Chronic Obstructive Pulmonary Disease and Lung Cancer: A Review for Clinicians. Chronic Obstr Pulm Dis. 2022 Jul 29; 9(3):454-476. PMID: 35790131; PMCID: PMC9448004.
      Citations:    
    12. Maldonado M, Villamin CE, Murphy LE, Dasgupta A, Bassett RL, Correa Medina M, Bates TS, Martinez F, Knopfelmacher Couchonal AM, Klein K, Kelley JM. Oncology Patients Who Develop Transfusion-Associated Circulatory Overload: An Observational Study. Lab Med. 2022 Jul 04; 53(4):344-348. PMID: 35285900; PMCID: PMC9251653.
      Citations:    Fields:    Translation:Humans
    13. Calverley PMA, Martinez FJ, Jenkins CR, Wise R, Lipson DA, Cowans NJ, Yates J, Crim C, Celli BR, Vestbo J. International Differences in the Frequency of Chronic Obstructive Pulmonary Disease Exacerbations Reported in Three Clinical Trials. Am J Respir Crit Care Med. 2022 07 01; 206(1):25-33. PMID: 35363593; PMCID: PMC9954323.
      Citations: 1     Fields:    Translation:Humans
    14. Singh D, Martinez FJ, Papi A, Pavord ID, Wedzicha JA, Vogelmeier CF, Halpin DMG, Agusti A. Blood Eosinophils and Chronic Obstructive Pulmonary Disease: A Global Initiative for Chronic Obstructive Lung Disease Science Committee 2022 Review. Am J Respir Crit Care Med. 2022 07 01; 206(1):17-24. PMID: 35737975.
      Citations:    Fields:    Translation:HumansCells
    15. Kheir F, Uribe Becerra JP, Bissell B, Ghazipura M, Herman D, Hon SM, Hossain T, Khor YH, Knight SL, Kreuter M, Macrea M, Mammen MJ, Martinez FJ, Troy L, Raghu G, Wilson KC, Poletti V. Transbronchial Lung Cryobiopsy in Patients with Interstitial Lung Disease: A Systematic Review. Ann Am Thorac Soc. 2022 07; 19(7):1193-1202. PMID: 35499855.
      Citations:    Fields:    Translation:Humans
    16. Choi B, Adan N, Doyle TJ, Humphries SM, Moll M, Cho MH, Putman RK, Hunninghake GM, Kalhan R, Liu GY, Diaz AA, Mason SE, Rahaghi FN, Pistenmaa CL, Enzer N, Poynton C, Ross JC, Martinez FJ, Han MK, Bowler RP, Wilson DO, Rosas IO, Washko GR, Ash SY, COPDGene Study and Pittsburgh Lung Screening Study Investigators, Harmouche R, Lynch DA, San Jos? Est?par R, S?nchez-Ferrero GV, San Jos? Est?par R. Quantitative Interstitial Abnormality Progression and Outcomes in the Genetic Epidemiology of COPD and Pittsburgh Lung Screening Study Cohorts. Chest. 2023 01; 163(1):164-175. PMID: 35780812; PMCID: PMC9859724.
      Citations:    Fields:    
    17. Kheir F, Uribe Becerra JP, Bissell B, Ghazipura M, Herman D, Hon SM, Hossain T, Khor YH, Knight SL, Kreuter M, Macrea M, Mammen MJ, Martinez FJ, Troy L, Raghu G, Wilson KC, Poletti V. Use of a Genomic Classifier in Patients with Interstitial Lung Disease: A Systematic Review and Meta-Analysis. Ann Am Thorac Soc. 2022 05; 19(5):827-832. PMID: 34077697.
      Citations: 1     Fields:    Translation:Humans
    18. Ronish BE, Couper DJ, Barjaktarevic IZ, Cooper CB, Kanner RE, Pirozzi CS, Kim V, Wells JM, Han MK, Woodruff PG, Ortega VE, Peters SP, Hoffman EA, Buhr RG, Dolezal BA, Tashkin DP, Liou TG, Bateman LA, Schroeder JD, Martinez FJ, Barr RG, Hansel NN, Comellas AP, Rennard SI, Arjomandi M, Paine Iii R. Forced Expiratory Flow at 25%-75% Links COPD Physiology to Emphysema and Disease Severity in the SPIROMICS Cohort. Chronic Obstr Pulm Dis. 2022 Apr 29; 9(2):111-121. PMID: 35114743; PMCID: PMC9166328.
      Citations: 1     
    19. Krishnan JK, Ancy KM, Oromendia C, Hoffman KL, Easthausen I, Leidy NK, Han MK, Bowler RP, Christenson SA, Couper DJ, Criner GJ, Curtis JL, Dransfield MT, Hansel NN, Iyer AS, Paine Iii R, Peters SP, Wedzicha JA, Woodruff PG, Ballman KV, Martinez FJ, SPIROMICS Investigators. Characterizing COPD Symptom Variability in the Stable State Utilizing the Evaluating Respiratory Symptoms in COPD Instrument. Chronic Obstr Pulm Dis. 2022 Apr 29; 9(2):195-208. PMID: 35403414; PMCID: PMC9166327.
      Citations:    
    20. Krishnan JK, Rajan M, Baer BR, Hoffman KL, Alshak MN, Aronson KI, Goyal P, Ezeomah C, Hill SS, Martinez FJ, Turetz ML, Wells MT, Safford MM, Schenck EJ. Assessing mortality differences across acute respiratory failure management strategies in Covid-19. J Crit Care. 2022 08; 70:154045. PMID: 35490502; PMCID: PMC9049881.
      Citations:    Fields:    Translation:Humans
    21. Singh D, Rabe KF, Martinez FJ, Jenkins M, Patel M, Dorinsky P, Kr?ll M. Relationship between prior inhaled corticosteroid use and benefits ofbudesonide/glycopyrronium/formoterol fumarate dihydrate on exacerbations, symptoms, health-related quality of life, and lung function in patients with chronic obstructive pulmonary disease: Analyses from the ETHOS study. Respir Med. 2022 06; 197:106857. PMID: 35512458.
      Citations:    Fields:    Translation:Humans
    22. Ghosh AJ, Hobbs BD, Yun JH, Saferali A, Moll M, Xu Z, Chase RP, Morrow J, Ziniti J, Sciurba F, Barwick L, Limper AH, Flaherty K, Criner G, Brown KK, Wise R, Martinez FJ, McGoldrick D, Cho MH, DeMeo DL, Silverman EK, Castaldi PJ, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Hersh CP. Lung tissue shows divergent gene expression between chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis. Respir Res. 2022 Apr 21; 23(1):97. PMID: 35449067; PMCID: PMC9026726.
      Citations:    Fields:    Translation:HumansCells
    23. Villamin C, Bates T, Mescher B, Benitez S, Martinez F, Knopfelmacher A, Correa Medina M, Klein K, Dasgupta A, Jaffray DA, Porter C, Tereffe W, Gallardo L, Kelley J. Digitally enabled hemovigilance allows real time response to transfusion reactions. Transfusion. 2022 05; 62(5):1010-1018. PMID: 35442519.
      Citations:    Fields:    Translation:HumansPHPublic Health
    24. Cottin V, Martinez FJ, Jenkins RG, Belperio JA, Kitamura H, Molina-Molina M, Tschoepe I, Coeck C, Lievens D, Costabel U. Safety and tolerability of nintedanib in patients with progressive fibrosing interstitial lung diseases: data from the randomized controlled INBUILD trial. Respir Res. 2022 Apr 07; 23(1):85. PMID: 35392908; PMCID: PMC8991727.
      Citations:    Fields:    Translation:Humans
    25. Belz DC, Woo H, Putcha N, Paulin LM, Koehler K, Fawzy A, Alexis NE, Barr RG, Comellas AP, Cooper CB, Couper D, Dransfield M, Gassett AJ, Han M, Hoffman EA, Kanner RE, Krishnan JA, Martinez FJ, Paine R, Peng RD, Peters S, Pirozzi CS, Woodruff PG, Kaufman JD, Hansel NN, SPIROMICS Investigators. Ambient ozone effects on respiratory outcomes among smokers modified by neighborhood poverty: An analysis of SPIROMICS AIR. Sci Total Environ. 2022 Jul 10; 829:154694. PMID: 35318050; PMCID: PMC9117415.
      Citations:    Fields:    Translation:HumansPHPublic Health
    26. Khanna D, Lin CJF, Furst DE, Wagner B, Zucchetto M, Raghu G, Martinez FJ, Goldin J, Siegel J, Denton CP. Long-Term Safety and Efficacy of Tocilizumab in Early Systemic Sclerosis-Interstitial Lung Disease: Open-Label Extension of a Phase 3 Randomized Controlled Trial. Am J Respir Crit Care Med. 2022 03 15; 205(6):674-684. PMID: 34851799.
      Citations: 3     Fields:    Translation:HumansCTClinical Trials
    27. Dransfield M, Rowe S, Vogelmeier CF, Wedzicha J, Criner GJ, Han MK, Martinez FJ, Calverley P. Cystic Fibrosis Transmembrane Conductance Regulator: Roles in Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2022 03 15; 205(6):631-640. PMID: 34982651.
      Citations:    Fields:    Translation:Humans
    28. Tabberer M, Jones CE, Kilbride S, Halpin DMG, Lomas DA, Pascoe S, Singh D, Wise RA, Criner GJ, Lange P, Dransfield MT, Han MK, Martinez FJ, Kaisermann MC, Lipson DA. Correction to: Single-Inhaler Triple Therapy and Health-Related Quality of Life in COPD: The IMPACT Study. Adv Ther. 2022 Mar; 39(3):1446. PMID: 35060093; PMCID: PMC9172769.
      Citations:    Fields:    
    29. O'Toole J, Woo H, Putcha N, Cooper CB, Woodruff P, Kanner RE, Paine R, Bowler RP, Comellas A, Hoth KF, Krishnan JA, Han M, Dransfield M, Iyer AS, Couper D, Peters SP, Criner G, Kim V, Barr RG, Martinez FJ, Hansel NN, Eakin MN, SPIROMICS Investigators. Comparative Impact of Depressive Symptoms and FEV1% on Chronic Obstructive Pulmonary Disease. Ann Am Thorac Soc. 2022 02; 19(2):171-178. PMID: 34410883; PMCID: PMC8867359.
      Citations:    Fields:    Translation:Humans
    30. Martinez FJ, Agusti A, Celli BR, Han MK, Allinson JP, Bhatt SP, Calverley P, Chotirmall SH, Chowdhury B, Darken P, Da Silva CA, Donaldson G, Dorinsky P, Dransfield M, Faner R, Halpin DM, Jones P, Krishnan JA, Locantore N, Martinez FD, Mullerova H, Price D, Rabe KF, Reisner C, Singh D, Vogelmeier CF, Wise RA, Tal-Singer R, Wedzicha JA, Vestbo J. Treatment Trials in Young Patients with Chronic Obstructive Pulmonary Disease and Pre-Chronic Obstructive Pulmonary Disease Patients: Time to Move Forward. Am J Respir Crit Care Med. 2022 02 01; 205(3):275-287. PMID: 34672872; PMCID: PMC8886994.
      Citations: 3     Fields:    Translation:Humans
    31. Ghosh AJ, Hobbs BD, Moll M, Saferali A, Boueiz A, Yun JH, Sciurba F, Barwick L, Limper AH, Flaherty K, Criner G, Brown KK, Wise R, Martinez FJ, Lomas D, Castaldi PJ, Carey VJ, DeMeo DL, Cho MH, Silverman EK, Hersh CP, COPDGene Investigators. Alpha-1 Antitrypsin MZ Heterozygosity Is an Endotype of Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2022 02 01; 205(3):313-323. PMID: 34762809; PMCID: PMC8886988.
      Citations: 3     Fields:    Translation:Humans
    32. Thomashow B, Stiegler M, Criner GJ, Dransfield MT, Halpin DMG, Han MK, Lange P, Martinez FJ, Midwinter D, Singh D, Tabberer M, Wise RA, Lipson DA, Jones P. Higher COPD Assessment Test Score Associated With Greater Exacerbations Risk: A Post Hoc Analysis of the IMPACT Trial. Chronic Obstr Pulm Dis. 2022 Jan 27; 9(1):68-79. PMID: 34972260; PMCID: PMC8893967.
      Citations:    
    33. Martinez FJ, Brochard L, Bush A, Donaldson G, Han MK. Advancing Global Respiratory Health, Sleep, and Critical Care: Editorial from the New American Journal of Respiratory and Critical Care Medicine Team. Am J Respir Crit Care Med. 2022 01 01; 205(1):i-ii. PMID: 34971340; PMCID: PMC8865581.
      Citations: 1     Fields:    Translation:Humans
    34. Singh D, Hurst JR, Martinez FJ, Rabe KF, Bafadhel M, Jenkins M, Salazar D, Dorinsky P, Darken P. Predictive modeling of COPD exacerbation rates using baseline risk factors. Ther Adv Respir Dis. 2022 Jan-Dec; 16:17534666221107314. PMID: 35815359; PMCID: PMC9340368.
      Citations:    Fields:    Translation:Humans
    35. Yang CX, Li X, Milne S, Chen V, Hollander Z, Ng R, Criner GJ, Woodruff PG, Lazarus SC, Connett JE, Han MK, Martinez FJ, Reed RM, Man SFP, Leung JM, Sin DD, Hern?ndez Cordero AI. Epigenetic marker of telomeric age is associated with exacerbations and hospitalizations in chronic obstructive pulmonary disease. Respir Res. 2021 Dec 22; 22(1):316. PMID: 34937547; PMCID: PMC8693486.
      Citations:    Fields:    Translation:HumansCells
    36. Wise RA, Bafadhel M, Crim C, Criner GJ, Day NC, Halpin DMG, Han MK, Lange P, Lipson DA, Martinez FJ, Maselli DJ, Midwinter D, Singh D, Zysman M, Dransfield MT, Russell REK. Discordant diagnostic criteria for pneumonia in COPD trials: a review. Eur Respir Rev. 2021 Dec 31; 30(162). PMID: 34789465; PMCID: PMC9488621.
      Citations:    Fields:    Translation:Humans
    37. Yee N, Markovic D, Buhr RG, Fortis S, Arjomandi M, Couper D, Anderson WH, Paine R, Woodruff PG, Han MK, Martinez FJ, Barr RG, Wells JM, Ortega VE, Hoffman EA, Kim V, Drummond MB, Bowler RP, Curtis JL, Cooper CB, Tashkin DP, Barjaktarevic IZ. Significance of FEV3/FEV6 in Recognition of Early Airway Disease in Smokers at Risk of Development of COPD: Analysis of the SPIROMICS Cohort. Chest. 2022 04; 161(4):949-959. PMID: 34767825; PMCID: PMC9005864.
      Citations:    Fields:    Translation:HumansCTClinical Trials
    38. Adeloye D, Agarwal D, Barnes PJ, Bonay M, van Boven JF, Bryant J, Caramori G, Dockrell D, D'Urzo A, Erhabor G, Greene CM, Hurst J, Juvekar S, Khoo EM, Ko FW, Lipworth B, Maddocks M, Mannino DM, Martinez FJ, McNamara RJ, Miravitlles M, Pinnock H, Pooler A, Quint JK, Schwarz P, Slavich GM, Song P, Tai A, Watz H, Wedzicha JA, Williams MC, Campbell H, Sheikh A, Rudan I, Ekstr?m M, Esteban C, L?pez-Campos JL, Martinez-Garcia MA. Research priorities to address the global burden of chronic obstructive pulmonary disease (COPD) in the next decade. J Glob Health. 2021; 11:15003. PMID: 34737870; PMCID: PMC8542376.
      Citations: 2     Fields:    Translation:Humans
    39. Bafadhel M, Barnes N, Bourke SC, Compton C, Criner GJ, Dransfield MT, Halpin DMG, Han MK, Hartley B, Jones CE, Lange P, Lettis S, Lipson DA, Lomas DA, Martin N, Martinez FJ, Wise R, Singh D. A single blood eosinophil count measurement is as good as two for prediction of ICS treatment response in the IMPACT trial. Eur Respir J. 2021 09; 58(3). PMID: 34385263.
      Citations:    Fields:    Translation:HumansCells
    40. Whalen W, Buyukozkan M, Moore B, Moon JS, Dela Cruz CS, Martinez FJ, Choi AMK, Krumsiek J, Stout-Delgado H, Cho SJ. Association of circulating cell-free double-stranded DNA and metabolic derangements in idiopathic pulmonary fibrosis. Thorax. 2022 02; 77(2):186-190. PMID: 34521729; PMCID: PMC8758529.
      Citations: 1     Fields:    Translation:Humans
    41. Yawn BP, Make B, Mannino D, Martinez FJ, Han MK. Letter to Editor Regarding the OCEAN Study [Letter]. Int J Chron Obstruct Pulmon Dis. 2021; 16:2501-2502. PMID: 34511894; PMCID: PMC8421258.
      Citations:    Fields:    Translation:Humans
    42. Woo H, Brigham EP, Allbright K, Ejike C, Galiatsatos P, Jones MR, Oates GR, Krishnan JA, Cooper CB, Kanner RE, Bowler RP, Hoffman EA, Comellas AP, Criner G, Barr RG, Martinez FJ, Han M, Ortega VE, Parekh TM, Christenson S, Belz D, Raju S, Gassett A, Paulin LM, Putcha N, Kaufman JD, Hansel NN. Racial Segregation and Respiratory Outcomes among Urban Black Residents with and at Risk of Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2021 09 01; 204(5):536-545. PMID: 33971109; PMCID: PMC8491265.
      Citations: 4     Fields:    Translation:Humans
    43. Martinez FJ, Darken P, Dorinsky P, all the authors. Perplexing mortality data from triple therapy trials in COPD - Author's reply. Lancet Respir Med. 2021 10; 9(10):e96. PMID: 34419214.
      Citations:    Fields:    Translation:Humans
    44. Barnes N, Gibson PG, Heaney LG, Inoue H, Leather D, Martinez FJ, McDonald VM, Oppenheimer J, Papi A, Pavord ID, Thomas M, Walker S, Yates L, Agusti A, Cruz AA. Moving towards a Treatable Traits model of care for the management of obstructive airways diseases. Respir Med. 2021 10; 187:106572. PMID: 34478992.
      Citations:    Fields:    Translation:Humans
    45. Aronson KI, O'Beirne R, Martinez FJ, Safford MM. Barriers to antigen detection and avoidance in chronic hypersensitivity pneumonitis in the United States. Respir Res. 2021 Aug 10; 22(1):225. PMID: 34376172; PMCID: PMC8353836.
      Citations: 1     Fields:    Translation:Humans
    46. Su C, Xu Z, Hoffman K, Goyal P, Safford MM, Lee J, Alvarez-Mulett S, Gomez-Escobar L, Price DR, Harrington JS, Torres LK, Martinez FJ, Campion TR, Wang F, Schenck EJ. Identifying organ dysfunction trajectory-based subphenotypes in critically ill patients with COVID-19. Sci Rep. 2021 08 05; 11(1):15872. PMID: 34354174; PMCID: PMC8342520.
      Citations: 7     Fields:    Translation:HumansCells
    47. Fawzy A, Woo H, Balasubramanian A, Barjaktarevic I, Barr RG, Bowler RP, Comellas AP, Cooper CB, Couper D, Criner GJ, Dransfield MT, Han MK, Hoffman EA, Kanner RE, Krishnan JA, Martinez FJ, McCormack M, Paine Iii R, Peters S, Wise R, Woodruff PG, Hansel NN, Putcha N. Polycythemia is Associated with Lower Incidence of Severe COPD Exacerbations in the SPIROMICS Study. Chronic Obstr Pulm Dis. 2021 Jul 28; 8(3):326-335. PMID: 34197703; PMCID: PMC8428597.
      Citations:    
    48. Brigham EP, Anderson JA, Brook RD, Calverley PMA, Celli BR, Cowans NJ, Crim C, Diserens JE, Martinez FJ, McCormack MC, Newby DE, Yates J, Vestbo J, Wu TD, Wise RA. Challenging the obesity paradox: extreme obesity and COPD mortality in the SUMMIT trial. ERJ Open Res. 2021 Jul; 7(3). PMID: 34322545; PMCID: PMC8311131.
      Citations: 3     
    49. Hisata S, Racanelli AC, Kermani P, Schreiner R, Houghton S, Palikuqi B, Kunar B, Zhou A, McConn K, Capili A, Redmond D, Nolan DJ, Ginsberg M, Ding BS, Martinez FJ, Scandura JM, Cloonan SM, Rafii S, Choi AMK. Reversal of emphysema by restoration of pulmonary endothelial cells. J Exp Med. 2021 08 02; 218(8). PMID: 34287647; PMCID: PMC8298104.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    50. Huang Y, Oldham JM, Ma SF, Unterman A, Liao SY, Barros AJ, Bonham CA, Kim JS, Vij R, Adegunsoye A, Strek ME, Molyneaux PL, Maher TM, Herazo-Maya JD, Kaminski N, Moore BB, Martinez FJ, Noth I. Blood Transcriptomics Predicts Progression of Pulmonary Fibrosis and Associated Natural Killer Cells. Am J Respir Crit Care Med. 2021 07 15; 204(2):197-208. PMID: 33689671; PMCID: PMC8650792.
      Citations: 6     Fields:    Translation:HumansCells
    51. Basar R, Uprety N, Ensley E, Daher M, Klein K, Martinez F, Aung F, Shanley M, Hu B, Gokdemir E, Nunez Cortes AK, Mendt M, Reyes Silva F, Acharya S, Laskowski T, Muniz-Feliciano L, Banerjee PP, Li Y, Li S, Melo Garcia L, Lin P, Shaim H, Yates SG, Marin D, Kaur I, Rao S, Mak D, Lin A, Miao Q, Dou J, Chen K, Champlin RE, Shpall EJ, Rezvani K. Generation of glucocorticoid-resistant SARS-CoV-2 T?cells for adoptive cell therapy. Cell Rep. 2021 07 20; 36(3):109432. PMID: 34270918; PMCID: PMC8260499.
      Citations: 9     Fields:    
    52. Martinez FJ, Afzal AS, Smith JA, Ford AP, Li JJ, Li Y, Kitt MM, Chronic Cough in IPF Study Group. Treatment of Persistent Cough in Subjects with Idiopathic Pulmonary Fibrosis (IPF) with Gefapixant, a P2X3 Antagonist, in a Randomized, Placebo-Controlled Clinical Trial. Pulm Ther. 2021 Dec; 7(2):471-486. PMID: 34152585; PMCID: PMC8589896.
      Citations: 2     
    53. Martinez FJ, Rabe KF, Ferguson GT, Wedzicha JA, Trivedi R, Jenkins M, Darken P, Aurivillius M, Dorinsky P. Benefits of budesonide/glycopyrrolate/formoterol fumarate (BGF) on symptoms and quality of life in patients with COPD in the ETHOS trial. Respir Med. 2021 Aug-Sep; 185:106509. PMID: 34171789.
      Citations: 1     Fields:    Translation:HumansCTClinical Trials
    54. Singh D, Donohue JF, Boucot IH, Barnes NC, Compton C, Martinez FJ. Future concepts in bronchodilation for COPD: dual- versus monotherapy. Eur Respir Rev. 2021 Jun 30; 30(160). PMID: 34415847; PMCID: PMC9489138.
      Citations:    Fields:    Translation:Humans
    55. Zou C, Li F, Choi J, Haghighi B, Choi S, Rajaraman PK, Comellas AP, Newell JD, Lee CH, Barr RG, Bleecker E, Cooper CB, Couper D, Han M, Hansel NN, Kanner RE, Kazerooni EA, Kleerup EC, Martinez FJ, O'Neal W, Paine R, Rennard SI, Smith BM, Woodruff PG, Hoffman EA, Lin CL. Longitudinal Imaging-Based Clusters in Former Smokers of the COPD Cohort Associate with Clinical Characteristics: The SubPopulations and Intermediate Outcome Measures in COPD Study (SPIROMICS). Int J Chron Obstruct Pulmon Dis. 2021; 16:1477-1496. PMID: 34103907; PMCID: PMC8178702.
      Citations:    Fields:    Translation:Humans
    56. Radicioni G, Ceppe A, Ford AA, Alexis NE, Barr RG, Bleecker ER, Christenson SA, Cooper CB, Han MK, Hansel NN, Hastie AT, Hoffman EA, Kanner RE, Martinez FJ, Ozkan E, Paine R, Woodruff PG, O'Neal WK, Boucher RC, Kesimer M. Airway mucin MUC5AC and MUC5B concentrations and the initiation and progression of chronic obstructive pulmonary disease: an analysis of the SPIROMICS cohort. Lancet Respir Med. 2021 11; 9(11):1241-1254. PMID: 34058148; PMCID: PMC8570975.
      Citations: 16     Fields:    Translation:Humans
    57. Martinez FJ, Yow E, Flaherty KR, Snyder LD, Durheim MT, Wisniewski SR, Sciurba FC, Raghu G, Brooks MM, Kim DY, Dilling DF, Criner GJ, Kim H, Belloli EA, Nambiar AM, Scholand MB, Anstrom KJ, Noth I, CleanUP-IPF Investigators of the Pulmonary Trials Cooperative. Effect of Antimicrobial Therapy on Respiratory Hospitalization or Death in Adults With Idiopathic Pulmonary Fibrosis: The CleanUP-IPF Randomized Clinical Trial. JAMA. 2021 05 11; 325(18):1841-1851. PMID: 33974018; PMCID: PMC8114133.
      Citations: 6     Fields:    Translation:Humans
    58. Dransfield MT, Crim C, Criner GJ, Day NC, Halpin DMG, Han MK, Jones CE, Kilbride S, LaFon D, Lipson DA, Lomas DA, Martin N, Martinez FJ, Singh D, Wise RA, Lange P. Risk of Exacerbation and Pneumonia with Single-Inhaler Triple versus Dual Therapy in IMPACT. Ann Am Thorac Soc. 2021 05; 18(5):788-798. PMID: 33108212; PMCID: PMC8086537.
      Citations: 2     Fields:    Translation:Humans
    59. Greenbaum U, Klein K, Martinez F, Song J, Thall PF, Ramdial JL, Knape C, Aung FM, Scroggins J, Knopfelmacher A, Mulanovich V, Borjan J, Adachi J, Muthu M, Leung C, Medina MC, Champlin R, Olson A, Alousi A, Rezvani K, Shpall EJ. High Levels of Common Cold Coronavirus Antibodies in Convalescent Plasma Are Associated With Improved Survival in COVID-19 Patients. Front Immunol. 2021; 12:675679. PMID: 33995420; PMCID: PMC8113636.
      Citations: 10     Fields:    Translation:HumansCellsCTClinical Trials
    60. Singh D, Criner GJ, Dransfield MT, Halpin DMG, Han MK, Lange P, Lettis S, Lipson DA, Mannino D, Martin N, Martinez FJ, Miller BE, Wise R, Zhu CQ, Lomas D. InforMing the PAthway of COPD Treatment (IMPACT) trial: fibrinogen levels predict risk of moderate or severe exacerbations. Respir Res. 2021 Apr 28; 22(1):130. PMID: 33910578; PMCID: PMC8080358.
      Citations: 2     Fields:    Translation:HumansCellsCTClinical Trials
    61. Martinez FJ, Thomashow B, Sapir T, Simone L, Carter J, Han M. Does Evaluation and Management of COPD Follow Therapeutic Strategy Recommendations? Chronic Obstr Pulm Dis. 2021 Apr 27; 8(2):230-242. PMID: 33610138; PMCID: PMC8237978.
      Citations: 1     
    62. Zhang WZ, Hoffman KL, Schiffer KT, Oromendia C, Rice MC, Barjaktarevic I, Peters SP, Putcha N, Bowler RP, Wells JM, Couper DJ, Labaki WW, Curtis JL, Han MK, Paine R, Woodruff PG, Criner GJ, Hansel NN, Diaz I, Ballman KV, Nakahira K, Choi ME, Martinez FJ, Choi AMK, Cloonan SM. Association of plasma mitochondrial DNA with COPD severity and progression in the SPIROMICS cohort. Respir Res. 2021 Apr 26; 22(1):126. PMID: 33902556; PMCID: PMC8074408.
      Citations: 3     Fields:    Translation:Humans
    63. Kasela S, Ortega VE, Martorella M, Garudadri S, Nguyen J, Ampleford E, Pasanen A, Nerella S, Buschur KL, Barjaktarevic IZ, Barr RG, Bleecker ER, Bowler RP, Comellas AP, Cooper CB, Couper DJ, Criner GJ, Curtis JL, Han MK, Hansel NN, Hoffman EA, Kaner RJ, Krishnan JA, Martinez FJ, McDonald MN, Meyers DA, Paine R, Peters SP, Castro M, Denlinger LC, Erzurum SC, Fahy JV, Israel E, Jarjour NN, Levy BD, Li X, Moore WC, Wenzel SE, Zein J, NHLBI SubPopulations and InteRmediate Outcome Measures In COPD Study (SPIROMICS), NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Langelier C, Woodruff PG, Lappalainen T, Christenson SA. Genetic and non-genetic factors affecting the expression of COVID-19-relevant genes in the large airway epithelium. Genome Med. 2021 Apr 21; 13(1):66. PMID: 33883027; PMCID: PMC8059115.
      Citations: 5     Fields:    Translation:HumansCells
    64. Dunican EM, Elicker BM, Henry T, Gierada DS, Schiebler ML, Anderson W, Barjaktarevic I, Barr RG, Bleecker ER, Boucher RC, Bowler R, Christenson SA, Comellas A, Cooper CB, Couper D, Criner GJ, Dransfield M, Doerschuk CM, Drummond MB, Hansel NN, Han MK, Hastie AT, Hoffman EA, Krishnan JA, Lazarus SC, Martinez FJ, McCulloch CE, O'Neal WK, Ortega VE, Paine R, Peters S, Schroeder JD, Woodruff PG, Fahy JV. Mucus Plugs and Emphysema in the Pathophysiology of Airflow Obstruction and Hypoxemia in Smokers. Am J Respir Crit Care Med. 2021 04 15; 203(8):957-968. PMID: 33180550; PMCID: PMC8048745.
      Citations: 12     Fields:    Translation:Humans
    65. Ejike CO, Woo H, Galiatsatos P, Paulin LM, Krishnan JA, Cooper CB, Couper DJ, Kanner RE, Bowler RP, Hoffman EA, Comellas AP, Criner GJ, Barr RG, Martinez FJ, Han MK, Martinez CH, Ortega VE, Parekh TM, Christenson SA, Thakur N, Baugh A, Belz DC, Raju S, Gassett AJ, Kaufman JD, Putcha N, Hansel NN. Contribution of Individual and Neighborhood Factors to Racial Disparities in Respiratory Outcomes. Am J Respir Crit Care Med. 2021 04 15; 203(8):987-997. PMID: 33007162; PMCID: PMC8048743.
      Citations: 8     Fields:    Translation:Humans
    66. Martinez FJ, Darken P, Dorinsky P. Reply to L?pez-Campos et al. and to Rogliani and Calzetta. Am J Respir Crit Care Med. 2021 04 01; 203(7):927-928. PMID: 33444510; PMCID: PMC8017589.
      Citations:    Fields:    Translation:Humans
    67. Lipson DA, Han MK, Wise R, Martinez FJ. Reply to L?pez-Campos et al.: Triple-Therapy Trials for Chronic Obstructive Pulmonary Disease: Methodological Considerations in the Mortality Effect. Am J Respir Crit Care Med. 2021 04 01; 203(7):928-929. PMID: 33444516; PMCID: PMC8017567.
      Citations:    Fields:    Translation:Humans
    68. Barnes NC, Jones P, Lipson DA, Singh D, Martinez FJ. Letter to editor - a response to: 'efficacy and safety of triple combination therapy for treating chronic obstructive pulmonary disease: an expert review'. Expert Opin Pharmacother. 2021 05; 22(7):939-941. PMID: 33655817.
      Citations:    Fields:    Translation:Humans
    69. Celli BR, Anderson JA, Cowans NJ, Crim C, Hartley BF, Martinez FJ, Morris AN, Quasny H, Yates J, Calverley PMA, Vestbo J. Pharmacotherapy and Lung Function Decline in Patients with Chronic Obstructive Pulmonary Disease. A Systematic Review. Am J Respir Crit Care Med. 2021 03 15; 203(6):689-698. PMID: 32966751; PMCID: PMC7958521.
      Citations: 10     Fields:    Translation:Humans
    70. Greenbaum U, Klein K, Martinez F, Song J, Thall PF, Ramdial JL, Knape C, Aung FM, Scroggins J, Knopfelmacher A, Mulanovich V, Borjan J, Adachi J, Muthu M, Leung C, Medina MC, Champlin R, Olson A, Alousi A, Rezvani K, Shpall EJ. High levels of common cold coronavirus antibodies in convalescent plasma are associated with improved survival in COVID-19 patients. medRxiv. 2021 Mar 10. PMID: 33758890; PMCID: PMC7987049.
      Citations:    
    71. Han MK, Criner GJ, Dransfield MT, Halpin DMG, Jones CE, Kilbride S, Lange P, Lettis S, Lipson DA, Lomas DA, Martin N, Martinez FJ, Wise RA, Naya IP, Singh D. Prognostic value of clinically important deterioration in COPD: IMPACT trial analysis. ERJ Open Res. 2021 Jan; 7(1). PMID: 33718490; PMCID: PMC7938047.
      Citations: 1     
    72. Li F, Choi J, Zou C, Newell JD, Comellas AP, Lee CH, Ko H, Barr RG, Bleecker ER, Cooper CB, Abtin F, Barjaktarevic I, Couper D, Han M, Hansel NN, Kanner RE, Paine R, Kazerooni EA, Martinez FJ, O'Neal W, Rennard SI, Smith BM, Woodruff PG, Hoffman EA, Lin CL. Latent traits of lung tissue patterns in former smokers derived by dual channel deep learning in computed tomography images. Sci Rep. 2021 03 01; 11(1):4916. PMID: 33649381; PMCID: PMC7921389.
      Citations: 3     Fields:    Translation:Humans
    73. Martinez FJ, Rabe KF, Ferguson GT, Wedzicha JA, Singh D, Wang C, Rossman K, St Rose E, Trivedi R, Ballal S, Darken P, Aurivillius M, Reisner C, Dorinsky P. Reduced All-Cause Mortality in the ETHOS Trial of Budesonide/Glycopyrrolate/Formoterol for Chronic Obstructive Pulmonary Disease. A Randomized, Double-Blind, Multicenter, Parallel-Group Study. Am J Respir Crit Care Med. 2021 03 01; 203(5):553-564. PMID: 33252985; PMCID: PMC7924571.
      Citations: 25     Fields:    Translation:Humans
    74. Nathan SD, Behr J, Hoeper MM, Martinez FJ, Corte TJ, Keogh AM, Leuchte H, Mogulkoc N, Wuyts WA, Yao Z, Ley-Zaporozhan J, Scholle FD, Busse D, Nikkho S, Wells AU, Cottin V, Ulrich S, M?ller-Lisse UG, Br?ggenwerth G. Impact of lung morphology on clinical outcomes with riociguat in patients with pulmonary hypertension and idiopathic interstitial pneumonia: A post hoc subgroup analysis of the RISE-IIP study. J Heart Lung Transplant. 2021 06; 40(6):494-503. PMID: 33744088.
      Citations: 1     Fields:    Translation:HumansCTClinical Trials
    75. Espindola MS, Habiel DM, Coelho AL, Stripp B, Parks WC, Oldham J, Martinez FJ, Noth I, Lopez D, Mikels-Vigdal A, Smith V, Hogaboam CM. Differential Responses to Targeting Matrix Metalloproteinase 9 in Idiopathic Pulmonary Fibrosis. Am J Respir Crit Care Med. 2021 02 15; 203(4):458-470. PMID: 33052708; PMCID: PMC7885832.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    76. Opron K, Begley LA, Erb-Downward JR, Freeman C, Madapoosi S, Alexis NE, Barjaktarevic I, Graham Barr R, Bleecker ER, Bowler RP, Christenson SA, Comellas AP, Cooper CB, Couper DJ, Doerschuk CM, Dransfield MT, Han MK, Hansel NN, Hastie AT, Hoffman EA, Kaner RJ, Krishnan J, O'Neal WK, Ortega VE, Paine R, Peters SP, Michael Wells J, Woodruff PG, Martinez FJ, Curtis JL, Huffnagle GB, Huang YJ. Lung microbiota associations with clinical features of COPD in the SPIROMICS cohort. NPJ Biofilms Microbiomes. 2021 02 05; 7(1):14. PMID: 33547327; PMCID: PMC7865064.
      Citations: 7     Fields:    Translation:HumansCells
    77. Martinez FJ, Ferguson GT, Bourne E, Ballal S, Darken P, Aurivillius M, Dorinsky P, Reisner C. Budesonide/Glycopyrrolate/Formoterol Fumarate Metered Dose Inhaler Improves Exacerbation Outcomes in Patients with COPD without a Recent Exacerbation History: A Subgroup Analysis of KRONOS. Int J Chron Obstruct Pulmon Dis. 2021; 16:179-189. PMID: 33542624; PMCID: PMC7851632.
      Citations: 4     Fields:    Translation:HumansCTClinical Trials
    78. Scholand MB, Lynch DA, Colby TV, Myers JL, Groshong SD, Chung JH, Benzaquen S, Nathan SD, Davis JR, Schmidt SL, Hagmeyer L, Sonetti D, Hetzel J, Criner GJ, Case AH, Ramaswamy M, Calero K, Gauhar UA, Patel NM, Lancaster L, Choi Y, Pankratz DG, Walsh PS, Lofaro LR, Huang J, Bhorade SM, Kennedy GC, Martinez FJ, Raghu G, Richeldi L. Utility of a Molecular Classifier as a Complement to High-Resolution Computed Tomography to Identify Usual Interstitial Pneumonia. Am J Respir Crit Care Med. 2021 01 15; 203(2):211-220. PMID: 32721166.
      Citations: 10     Fields:    Translation:HumansCTClinical Trials
    79. Aronson KI, Ali M, Reshetynak E, Kaner RJ, Martinez FJ, Safford MM, Pinheiro LC. Establishing content-validity of a disease-specific health-related quality of life instrument for patients with chronic hypersensitivity pneumonitis. J Patient Rep Outcomes. 2021 Jan 14; 5(1):9. PMID: 33443657; PMCID: PMC7809073.
      Citations: 1     
    80. Yawn BP, Han M, Make BM, Mannino D, Brown RW, Meldrum C, Murray S, Spino C, Bronicki JS, Leidy N, Tapp H, Dolor RJ, Joo M, Knox L, Zittleman L, Thomashow BM, Martinez FJ. Protocol Summary of the COPD Assessment in Primary Care To Identify Undiagnosed Respiratory Disease and Exacerbation Risk (CAPTURE) Validation in Primary Care Study. Chronic Obstr Pulm Dis. 2021 Jan; 8(1). PMID: 33156981; PMCID: PMC8047605.
      Citations: 3     
    81. Halpin DMG, Criner GJ, Papi A, Singh D, Anzueto A, Martinez FJ, Agusti AA, Vogelmeier CF. Global Initiative for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease. The 2020 GOLD Science Committee Report on COVID-19 and Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2021 01 01; 203(1):24-36. PMID: 33146552; PMCID: PMC7781116.
      Citations: 94     Fields:    Translation:HumansCells
    82. Han MK, Lipson DA, Singh D, Martinez FJ. Reply to Wang and Lai: The Role of Eosinophils during the Withdrawal of Inhaled Corticosteroids in Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2021 01 01; 203(1):145-148. PMID: 32986463; PMCID: PMC7781138.
      Citations:    Fields:    Translation:HumansCells
    83. Rabe KF, Martinez FJ, Singh D, Trivedi R, Jenkins M, Darken P, Aurivillius M, Dorinsky P. Improvements in lung function with budesonide/glycopyrrolate/formoterol fumarate metered dose inhaler versus dual therapies in patients with COPD: a sub-study of the ETHOS trial. Ther Adv Respir Dis. 2021 Jan-Dec; 15:17534666211034329. PMID: 34428980; PMCID: PMC8392797.
      Citations: 2     Fields:    Translation:HumansCTClinical Trials
    84. Han MK, Lipson DA, Singh D, Martinez FJ. Reply to: 'evaluating triple ICS/LABA/LAMA therapies for COPD patients: a network meta-analysis of ETHOS, KRONOS, IMPACT, and TRILOGY studies'. Expert Rev Respir Med. 2021 04; 15(4):577-578. PMID: 33336588.
      Citations: 1     Fields:    Translation:Humans
    85. Labaki WW, Xia M, Murray S, Hatt CR, Al-Abcha A, Ferrera MC, Meldrum CA, Keith LA, Arenberg DA, Curtis JL, Martinez FJ, Kazerooni EA, Han MK, Galb?n CJ. Quantitative Emphysema on Low-Dose CT Imaging of the Chest and Risk of Lung Cancer and Airflow Obstruction: An Analysis of the National Lung Screening Trial. Chest. 2021 05; 159(5):1812-1820. PMID: 33326807; PMCID: PMC8129730.
      Citations: 9     Fields:    Translation:HumansPHPublic Health
    86. Tervonen T, Martinez FJ, Hanania NA, Heidenreich S, Eudicone JM, Gilbert I. Dual-combination maintenance inhaler preferences in asthma and chronic obstructive pulmonary disease: A patient-centered benefit-risk assessment. Respir Med. 2021 01; 176:106278. PMID: 33387985.
      Citations: 1     Fields:    
    87. Kim V, Jeong S, Zhao H, Kesimer M, Boucher RC, Wells JM, Christenson SA, Han MK, Dransfield M, Paine R, Cooper CB, Barjaktarevic I, Bowler R, Curtis JL, Kaner RJ, O'Beirne SL, O'Neal WK, Rennard SI, Martinez FJ, Woodruff PG. Current smoking with or without chronic bronchitis is independently associated with goblet cell hyperplasia in healthy smokers and COPD subjects. Sci Rep. 2020 11 18; 10(1):20133. PMID: 33208859; PMCID: PMC7674445.
      Citations: 1     Fields:    Translation:HumansCells
    88. Halpin DMG, Criner GJ, Dransfield MT, Han MK, Hartley B, Harvey C, Jones CE, Kato M, Lange P, Lettis S, Lomas DA, Martinez FJ, Martin N, Singh D, Wise R, Zheng J, Lipson DA. Triple Versus Dual Combination Therapy in Chronic Obstructive Pulmonary Disease in Asian Countries: Analysis of the IMPACT Trial. Pulm Ther. 2021 Jun; 7(1):101-118. PMID: 33201438; PMCID: PMC8137798.
      Citations: 2     
    89. Han MK, Lipson DA, Singh D, Martinez FJ. One More Time: The Impact of Inhaled Corticosteroid Withdrawal on IMPACT. Am J Respir Crit Care Med. 2020 11 01; 202(9):1205-1206. PMID: 32758100; PMCID: PMC7605195.
      Citations: 1     Fields:    
    90. Han MK, Criner GJ, Dransfield MT, Halpin DMG, Jones CE, Kilbride S, Lange P, Lettis S, Lipson DA, Lomas DA, Martin N, Wise RA, Singh D, Martinez FJ. The Effect of Inhaled Corticosteroid Withdrawal and Baseline Inhaled Treatment on Exacerbations in the IMPACT Study. A Randomized, Double-Blind, Multicenter Clinical Trial. Am J Respir Crit Care Med. 2020 11 01; 202(9):1237-1243. PMID: 32584168; PMCID: PMC7605201.
      Citations: 10     Fields:    Translation:Humans
    91. Stott-Miller M, Miller B, Tabberer M, Keeley T, Martinez FJ, Han M, Dransfield M, Hansel NN, Cooper CB, Woodruff P, Ortega VE, Comellas AP, Paine Iii R, Kanner RE, Anderson W, Drummond MB, Kim V, Tal-Singer R, Lazaar AL, M?llerov? H, El Baou C. Defining Chronic Mucus Hypersecretion Using the CAT in the SPIROMICS Cohort. Int J Chron Obstruct Pulmon Dis. 2020; 15:2467-2476. PMID: 33116463; PMCID: PMC7568676.
      Citations: 3     Fields:    Translation:Humans
    92. Hanania NA, Mannino DM, Criner GJ, Dransfield MT, Han MK, Jones CE, Kilbride S, Lomas DA, Martin N, Martinez FJ, Singh D, Wise RA, Halpin DMG, Lima R, Lipson DA. Effect of Age on the Efficacy and Safety of Once-Daily Single-Inhaler Triple-Therapy Fluticasone Furoate/Umeclidinium/Vilanterol in Patients With COPD: A Post Hoc Analysis of the Informing the Pathway of COPD Treatment Trial. Chest. 2021 03; 159(3):985-995. PMID: 33031829.
      Citations: 2     Fields:    Translation:HumansCTClinical Trials
    93. Rabe KF, Martinez FJ, Dorinsky P. Triple Inhaled Therapy in COPD. Reply. N Engl J Med. 2020 10 01; 383(14):1394-1395. PMID: 32997922.
      Citations:    Fields:    Translation:Humans
    94. Basar R, Uprety N, Ensley E, Daher M, Klein K, Martinez F, Aung F, Shanley M, Hu B, Gokdemir E, Mendt M, Silva FR, Acharya S, Laskowski T, Muniz-Feliciano L, Banerjee P, Li Y, Li S, Garcia LM, Lin P, Shaim H, Yates SG, Marin D, Kaur I, Rao S, Mak D, Lin A, Miao Q, Dou J, Chen K, Champlin R, Shpall EJ, Rezvani K. Generation of glucocorticoid resistant SARS-CoV-2 T-cells for adoptive cell therapy. bioRxiv. 2020 Sep 15. PMID: 32995792; PMCID: PMC7523118.
      Citations: 1     
    95. Han MK, Martinez FJ. Host, Gender, and Early-Life Factors as Risks for Chronic Obstructive Pulmonary Disease. Clin Chest Med. 2020 09; 41(3):329-337. PMID: 32800188; PMCID: PMC7993923.
      Citations: 1     Fields:    Translation:Humans
    96. Schenck EJ, Hoffman K, Goyal P, Choi J, Torres L, Rajwani K, Tam CW, Ivascu N, Martinez FJ, Berlin DA. Respiratory Mechanics and Gas Exchange in COVID-19-associated Respiratory Failure. Ann Am Thorac Soc. 2020 09; 17(9):1158-1161. PMID: 32432896; PMCID: PMC7462323.
      Citations: 51     Fields:    Translation:HumansCellsPHPublic Health
    97. Singh D, Bafadhel M, Brightling CE, Sciurba FC, Curtis JL, Martinez FJ, Pasquale CB, Merrill DD, Metzdorf N, Petruzzelli S, Tal-Singer R, Compton C, Rennard S, Martin UJ. Blood Eosinophil Counts in Clinical Trials for Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2020 09 01; 202(5):660-671. PMID: 32186896; PMCID: PMC7462391.
      Citations: 22     Fields:    Translation:HumansCells
    98. Montesi SB, Fisher JH, Martinez FJ, Johannson KA, Selman M, Pardo A. Update in Interstitial Lung Disease 2019. Am J Respir Crit Care Med. 2020 08 15; 202(4):500-507. PMID: 32412784; PMCID: PMC7427378.
      Citations: 2     Fields:    Translation:Humans
    99. Cooper CB, Paine R, Curtis JL, Kanner RE, Martinez CH, Meldrum CA, Bowler R, O'Neal W, Hoffman EA, Couper D, Quibrera M, Criner G, Dransfield MT, Han MK, Hansel NN, Krishnan JA, Lazarus SC, Peters SP, Barr RG, Martinez FJ, Woodruff PG, SPIROMICS investigators. Novel Respiratory Disability Score Predicts COPD Exacerbations and Mortality in the SPIROMICS Cohort. Int J Chron Obstruct Pulmon Dis. 2020; 15:1887-1898. PMID: 32821092; PMCID: PMC7417644.
      Citations: 1     Fields:    Translation:Humans
    100. Halpin DMG, Han MK, Miravitlles M, Singh D, Martinez FJ, Rabe KF, Gr?nke L, Vo? F. Composite endpoints in COPD: clinically important deterioration in the UPLIFT trial. Respir Res. 2020 Jul 09; 21(1):177. PMID: 32646424; PMCID: PMC7350568.
      Citations: 4     Fields:    Translation:Humans
    101. Tabberer M, Jones CE, Kilbride S, Halpin DMG, Lomas DA, Pascoe S, Singh D, Wise RA, Criner GJ, Lange P, Dransfield MT, Han MK, Martinez FJ, Kaisermann MC, Lipson DA. Single-Inhaler Triple Therapy and Health-Related Quality of Life in COPD: The IMPACT Study. Adv Ther. 2020 09; 37(9):3775-3790. PMID: 32647911; PMCID: PMC7444357.
      Citations:    Fields:    Translation:Humans
    102. Goyal P, Ringel JB, Rajan M, Choi JJ, Pinheiro LC, Li HA, Wehmeyer GT, Alshak MN, Jabri A, Schenck EJ, Chen R, Satlin MJ, Campion TR, Nahid M, Plataki M, Hoffman KL, Reshetnyak E, Hupert N, Horn EM, Martinez FJ, Gulick RM, Safford MM. Obesity and COVID-19 in New York City: A Retrospective Cohort Study. Ann Intern Med. 2020 11 17; 173(10):855-858. PMID: 32628537; PMCID: PMC7384267.
      Citations: 42     Fields:    Translation:HumansCellsPHPublic Health
    103. Tervonen T, Hawken N, Hanania NA, Martinez FJ, Heidenreich S, Gilbert I. Maintenance inhaler therapy preferences of patients with asthma or chronic obstructive pulmonary disease: a discrete choice experiment. Thorax. 2020 09; 75(9):735-743. PMID: 32631932; PMCID: PMC7476258.
      Citations: 7     Fields:    Translation:Humans
    104. Zhang WZ, Oromendia C, Kikkers SA, Butler JJ, O'Beirne S, Kim K, O'Neal WK, Freeman CM, Christenson SA, Peters SP, Wells JM, Doerschuk C, Putcha N, Barjaktarevic I, Woodruff PG, Cooper CB, Bowler RP, Comellas AP, Criner GJ, Paine R, Hansel NN, Han MK, Crystal RG, Kaner RJ, Ballman KV, Curtis JL, Martinez FJ, Cloonan SM. Increased airway iron parameters and risk for exacerbation in COPD: an analysis from SPIROMICS. Sci Rep. 2020 06 29; 10(1):10562. PMID: 32601308; PMCID: PMC7324559.
      Citations: 8     Fields:    Translation:HumansCTClinical Trials
    105. Rabe KF, Martinez FJ, Ferguson GT, Wang C, Singh D, Wedzicha JA, Trivedi R, St Rose E, Ballal S, McLaren J, Darken P, Aurivillius M, Reisner C, Dorinsky P, ETHOS Investigators. Triple Inhaled Therapy at Two Glucocorticoid Doses in Moderate-to-Very-Severe COPD. N Engl J Med. 2020 07 02; 383(1):35-48. PMID: 32579807.
      Citations: 69     Fields:    Translation:HumansCTClinical Trials
    106. John TM, Malek AE, Mulanovich VE, Adachi JA, Raad II, Hamilton AR, Shpall EJ, Rezvani K, Aitken SL, Jain N, Klein K, Martinez F, Jacob CN, Cherian SV, Manzano JM, Muthu M, Wegner R. Migratory Pulmonary Infiltrates in a Patient With COVID-19 Infection and the Role of Corticosteroids. Mayo Clin Proc. 2020 09; 95(9):2038-2040. PMID: 32861345; PMCID: PMC7311909.
      Citations: 2     Fields:    Translation:HumansCellsPHPublic Health
    107. Chotirmall SH, Martinez FJ, Schumacker PT, Cooke CR, Seam N, Brochard L, Tighe RM, Levy BD, Gern D, Wedzicha JA. Life at the Editorial "COVID Frontline". The American Thoracic Society Journal Family. Am J Respir Crit Care Med. 2020 06 15; 201(12):1457-1459. PMID: 32356668; PMCID: PMC7301742.
      Citations: 6     Fields:    Translation:HumansCellsPHPublic Health
    108. Lipson DA, Crim C, Criner GJ, Day NC, Dransfield MT, Halpin DMG, Han MK, Jones CE, Kilbride S, Lange P, Lomas DA, Lettis S, Manchester P, Martin N, Midwinter D, Morris A, Pascoe SJ, Singh D, Wise RA, Martinez FJ. Reduction in All-Cause Mortality with Fluticasone Furoate/Umeclidinium/Vilanterol in Patients with Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2020 06 15; 201(12):1508-1516. PMID: 32162970; PMCID: PMC7301738.
      Citations: 37     Fields:    Translation:Humans
    109. Smith BM, Kirby M, Hoffman EA, Kronmal RA, Aaron SD, Allen NB, Bertoni A, Coxson HO, Cooper C, Couper DJ, Criner G, Dransfield MT, Han MK, Hansel NN, Jacobs DR, Kaufman JD, Lin CL, Manichaikul A, Martinez FJ, Michos ED, Oelsner EC, Paine R, Watson KE, Benedetti A, Tan WC, Bourbeau J, Woodruff PG, Barr RG, MESA Lung, CanCOLD, and SPIROMICS Investigators. Association of Dysanapsis With Chronic Obstructive Pulmonary Disease Among Older Adults. JAMA. 2020 06 09; 323(22):2268-2280. PMID: 32515814; PMCID: PMC7284296.
      Citations: 22     Fields:    Translation:Humans
    110. Day NC, Kumar S, Criner G, Dransfield M, Halpin DMG, Han MK, Jones CE, Kaisermann MC, Kilbride S, Lange P, Lomas DA, Martin N, Martinez FJ, Singh D, Wise R, Lipson DA. Single-inhaler triple therapy fluticasone furoate/umeclidinium/vilanterol versus fluticasone furoate/vilanterol and umeclidinium/vilanterol in patients with COPD: results on cardiovascular safety from the IMPACT trial. Respir Res. 2020 Jun 05; 21(1):139. PMID: 32503599; PMCID: PMC7275457.
      Citations: 1     Fields:    Translation:HumansCTClinical Trials
    111. Hou YJ, Okuda K, Edwards CE, Martinez DR, Asakura T, Dinnon KH, Kato T, Lee RE, Yount BL, Mascenik TM, Chen G, Olivier KN, Ghio A, Tse LV, Leist SR, Gralinski LE, Dang H, Gilmore R, Nakano S, Sun L, Fulcher ML, Livraghi-Butrico A, Nicely NI, Cameron M, Cameron C, Kelvin DJ, de Silva A, Margolis DM, Markmann A, Bartelt L, Zumwalt R, Martinez FJ, Salvatore SP, Borczuk A, Tata PR, Sontake V, Kimple A, Jaspers I, O'Neal WK, Randell SH, Boucher RC, Baric RS, Sch?fer A. SARS-CoV-2 Reverse Genetics Reveals a Variable Infection Gradient in the Respiratory Tract. Cell. 2020 07 23; 182(2):429-446.e14. PMID: 32526206; PMCID: PMC7250779.
      Citations: 520     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    112. Martinez FJ, Lipworth BJ, Rabe KF, Collier DJ, Ferguson GT, Sethi S, Feldman GJ, O'Brien G, Jenkins M, Reisner C. Benefits of glycopyrrolate/formoterol fumarate metered dose inhaler (GFF MDI) in improving lung function and reducing exacerbations in patients with moderate-to-very severe COPD: a pooled analysis of the PINNACLE studies. Respir Res. 2020 May 25; 21(1):128. PMID: 32450869; PMCID: PMC7249639.
      Citations: 1     Fields:    Translation:Humans
    113. Putcha N, Fawzy A, Matsui EC, Liu MC, Bowler RP, Woodruff PG, O'Neal WK, Comellas AP, Han MK, Dransfield MT, Wells JM, Lugogo N, Gao L, Talbot CC, Hoffman EA, Cooper CB, Paulin LM, Kanner RE, Criner G, Ortega VE, Barr RG, Krishnan JA, Martinez FJ, Drummond MB, Wise RA, Diette GB, Hersh CP, Hansel NN. Clinical Phenotypes of Atopy and Asthma in COPD: A Meta-analysis of SPIROMICS and COPDGene. Chest. 2020 12; 158(6):2333-2345. PMID: 32450244; PMCID: PMC7768932.
      Citations: 6     Fields:    Translation:Humans
    114. Leitao Filho FS, Mattman A, Schellenberg R, Criner GJ, Woodruff P, Lazarus SC, Albert RK, Connett J, Han MK, Gay SE, Martinez FJ, Fuhlbrigge AL, Stoller JK, MacIntyre NR, Casaburi R, Diaz P, Panos RJ, Cooper JA, Bailey WC, LaFon DC, Sciurba FC, Kanner RE, Yusen RD, Au DH, Pike KC, Fan VS, Leung JM, Man SP, Aaron SD, Reed RM, Sin DD. Serum IgG Levels and Risk of COPD Hospitalization: A Pooled Meta-analysis. Chest. 2020 10; 158(4):1420-1430. PMID: 32439504.
      Citations: 7     Fields:    Translation:Humans
    115. Crim C, Anderson JA, Calverley PMA, Celli BR, Cowans NJ, Martinez FJ, Newby DE, Yates JC, Brook RD, Vestbo J. Pulse Wave Velocity in Chronic Obstructive Pulmonary Disease and the Impact of Inhaled Therapy (SUMMIT): A Randomized Double-Blind Clinical Trial. Am J Respir Crit Care Med. 2020 05 15; 201(10):1307-1310. PMID: 32017597.
      Citations: 4     Fields:    Translation:Humans
    116. Berlin DA, Gulick RM, Martinez FJ. Severe Covid-19. N Engl J Med. 2020 Dec 17; 383(25):2451-2460. PMID: 32412710.
      Citations: 409     Fields:    Translation:HumansCells
    117. Raghu G, Colby TV, Myers JL, Steele MP, Benzaquen S, Calero K, Case AH, Criner GJ, Nathan SD, Rai NS, Hagmeyer L, Davis JR, Bhorade SM, Kennedy GC, Gauher UA, Martinez FJ. A Molecular Classifier That Identifies Usual Interstitial Pneumonia in Transbronchial Biopsy Specimens of Patients With Interstitial Lung Disease. Chest. 2020 05; 157(5):1391-1392. PMID: 32386639.
      Citations:    Fields:    Translation:Humans
    118. Nici L, Mammen MJ, Charbek E, Alexander PE, Au DH, Boyd CM, Criner GJ, Donaldson GC, Dreher M, Fan VS, Gershon AS, Han MK, Krishnan JA, Martinez FJ, Meek PM, Morgan M, Polkey MI, Puhan MA, Sadatsafavi M, Sin DD, Washko GR, Wedzicha JA, Aaron SD. Pharmacologic Management of Chronic Obstructive Pulmonary Disease. An Official American Thoracic Society Clinical Practice Guideline. Am J Respir Crit Care Med. 2020 05 01; 201(9):e56-e69. PMID: 32283960; PMCID: PMC7193862.
      Citations: 64     Fields:    Translation:Humans
    119. Hanania NA, Papi A, Anzueto A, Martinez FJ, Rossman KA, Cappelletti CS, Duncan EA, Nyberg JS, Dorinsky PM. Efficacy and safety of two doses of budesonide/formoterol fumarate metered dose inhaler in COPD. ERJ Open Res. 2020 Apr; 6(2). PMID: 32363206; PMCID: PMC7184113.
      Citations: 1     
    120. Goyal P, Choi JJ, Pinheiro LC, Schenck EJ, Chen R, Jabri A, Satlin MJ, Campion TR, Nahid M, Ringel JB, Hoffman KL, Alshak MN, Li HA, Wehmeyer GT, Rajan M, Reshetnyak E, Hupert N, Horn EM, Martinez FJ, Gulick RM, Safford MM. Clinical Characteristics of Covid-19 in New York City. N Engl J Med. 2020 06 11; 382(24):2372-2374. PMID: 32302078; PMCID: PMC7182018.
      Citations: 905     Fields:    Translation:HumansCellsPHPublic Health
    121. Keller T, Spece LJ, Donovan LM, Udris E, Coggeshall SS, Griffith M, Bryant AD, Casaburi R, Cooper JA, Criner GJ, Diaz PT, Fuhlbrigge AL, Gay SE, Kanner RE, Martinez FJ, Panos RJ, Shade D, Sternberg A, Stibolt T, Stoller JK, Tonascia J, Wise R, Yusen RD, Au DH, Feemster LC. Association of Guideline-Recommended COPD Inhaler Regimens With Mortality, Respiratory Exacerbations, and Quality of Life: A Secondary Analysis of the Long-Term Oxygen Treatment Trial. Chest. 2020 08; 158(2):529-538. PMID: 32278779; PMCID: PMC7417382.
      Citations: 2     Fields:    Translation:Humans
    122. Vasilescu DM, Hackett TL, Martinez FJ, Curtis JL, Hogg JC, Han MK. Reply to Janssen and Wouters: Loss of Alveolar Attachments as a Pathomechanistic Link between Small Airway Disease and Emphysema. Am J Respir Crit Care Med. 2020 04 01; 201(7):879-880. PMID: 31804850; PMCID: PMC7124715.
      Citations:    Fields:    Translation:Humans
    123. Anstrom KJ, Noth I, Flaherty KR, Edwards RH, Albright J, Baucom A, Brooks M, Clark AB, Clausen ES, Durheim MT, Kim DY, Kirchner J, Oldham JM, Snyder LD, Wilson AM, Wisniewski SR, Yow E, Martinez FJ, CleanUP-IPF Study Team. Design and rationale of a multi-center, pragmatic, open-label randomized trial of antimicrobial therapy - the study of clinical efficacy of antimicrobial therapy strategy using pragmatic design in Idiopathic Pulmonary Fibrosis (CleanUP-IPF) clinical trial. Respir Res. 2020 Mar 12; 21(1):68. PMID: 32164673; PMCID: PMC7069004.
      Citations: 10     Fields:    Translation:Humans
    124. Ortega VE, Li X, O'Neal WK, Lackey L, Ampleford E, Hawkins GA, Grayeski PJ, Laederach A, Barjaktarevic I, Barr RG, Cooper C, Couper D, Han MK, Kanner RE, Kleerup EC, Martinez FJ, Paine R, Peters SP, Pirozzi C, Rennard SI, Woodruff PG, Hoffman EA, Meyers DA, Bleecker ER, NHLBI Subpopulations and Intermediate Outcomes Measures in COPD Study (SPIROMICS). The Effects of Rare SERPINA1 Variants on Lung Function and Emphysema in SPIROMICS. Am J Respir Crit Care Med. 2020 03 01; 201(5):540-554. PMID: 31661293; PMCID: PMC7047460.
      Citations: 12     Fields:    Translation:Humans
    125. Zhang WZ, Rice MC, Hoffman KL, Oromendia C, Barjaktarevic IZ, Wells JM, Hastie AT, Labaki WW, Cooper CB, Comellas AP, Criner GJ, Krishnan JA, Paine R, Hansel NN, Bowler RP, Barr RG, Peters SP, Woodruff PG, Curtis JL, Han MK, Ballman KV, Martinez FJ, Choi AM, Nakahira K, Cloonan SM, Choi ME, SPIROMICS Investigators. Association of urine mitochondrial DNA with clinical measures of COPD in the SPIROMICS cohort. JCI Insight. 2020 02 13; 5(3). PMID: 31895696; PMCID: PMC7098791.
      Citations: 13     Fields:    Translation:Humans
    126. Singh D, Martinez FJ, Watz H, Bengtsson T, Maurer BT. A dose-ranging study of the inhaled dual phosphodiesterase 3 and 4 inhibitor ensifentrine in COPD. Respir Res. 2020 Feb 10; 21(1):47. PMID: 32041601; PMCID: PMC7011474.
      Citations: 9     Fields:    Translation:HumansCTClinical Trials
    127. Han MK, Barreto TA, Martinez FJ, Comstock AT, Sajjan US. Randomised clinical trial to determine the safety of quercetin supplementation in patients with chronic obstructive pulmonary disease. BMJ Open Respir Res. 2020 02; 7(1). PMID: 32071149; PMCID: PMC7047491.
      Citations: 12     Translation:HumansCTClinical Trials
    128. Martinez FJ, Rabe KF, Lipworth BJ, Arora S, Jenkins M, Martin UJ, Reisner C. Glycopyrrolate/Formoterol Fumarate Metered Dose Inhaler Improves Lung Function versus Monotherapies in GOLD Category A Patients with COPD: Pooled Data from the Phase III PINNACLE Studies. Int J Chron Obstruct Pulmon Dis. 2020; 15:99-106. PMID: 32021148; PMCID: PMC6957003.
      Citations: 3     Fields:    Translation:Humans
    129. Paulin LM, Gassett AJ, Alexis NE, Kirwa K, Kanner RE, Peters S, Krishnan JA, Paine R, Dransfield M, Woodruff PG, Cooper CB, Barr RG, Comellas AP, Pirozzi CS, Han M, Hoffman EA, Martinez FJ, Woo H, Peng RD, Fawzy A, Putcha N, Breysse PN, Kaufman JD, Hansel NN, for SPIROMICS investigators. Association of Long-term Ambient Ozone Exposure With Respiratory Morbidity in Smokers. JAMA Intern Med. 2020 01 01; 180(1):106-115. PMID: 31816012; PMCID: PMC6902160.
      Citations: 16     Fields:    Translation:HumansPHPublic Health
    130. Yawn BP, Martinez FJ. Rebuttal From Drs Yawn and?Martinez. Chest. 2020 01; 157(1):12-14. PMID: 31916954.
      Citations:    Fields:    Translation:Humans
    131. Yawn BP, Martinez FJ. POINT: Can Screening for COPD Improve Outcomes? Yes. Chest. 2020 01; 157(1):7-9. PMID: 31916966.
      Citations: 6     Fields:    Translation:HumansPHPublic Health
    132. Barjaktarevic IZ, Buhr RG, Wang X, Hu S, Couper D, Anderson W, Kanner RE, Paine Iii R, Bhatt SP, Bhakta NR, Arjomandi M, Kaner RJ, Pirozzi CS, Curtis JL, O'Neal WK, Woodruff PG, Han MK, Martinez FJ, Hansel N, Wells JM, Ortega VE, Hoffman EA, Doerschuk CM, Kim V, Dransfield MT, Drummond MB, Bowler R, Criner G, Christenson SA, Ronish B, Peters SP, Krishnan JA, Tashkin DP, Cooper CB, NHLBI SubPopulations and InteRmediate Outcome Measures In COPD Study (SPIROMICS). Clinical Significance of Bronchodilator Responsiveness Evaluated by Forced Vital Capacity in COPD: SPIROMICS Cohort Analysis. Int J Chron Obstruct Pulmon Dis. 2019; 14:2927-2938. PMID: 31908441; PMCID: PMC6930016.
      Citations: 1     Fields:    Translation:Humans
    133. Criner RN, Hatt CR, Kazerooni EA, Lynch DA, McCormack MC, Casaburi R, MacIntyre NR, Make BJ, Martinez FJ, Labaki WW, Curtis JL, Han MLK, Galb?n CJ. Relationship between diffusion capacity and small airway abnormality in COPDGene. Respir Res. 2019 Dec 02; 20(1):269. PMID: 31791337; PMCID: PMC6889734.
      Citations: 11     Fields:    Translation:Humans
    134. Lowe KE, Regan EA, Anzueto A, Austin E, Austin JHM, Beaty TH, Benos PV, Benway CJ, Bhatt SP, Bleecker ER, Bodduluri S, Bon J, Boriek AM, Boueiz AR, Bowler RP, Budoff M, Casaburi R, Castaldi PJ, Charbonnier JP, Cho MH, Comellas A, Conrad D, Costa Davis C, Criner GJ, Curran-Everett D, Curtis JL, DeMeo DL, Diaz AA, Dransfield MT, Dy JG, Fawzy A, Fleming M, Flenaugh EL, Foreman MG, Fortis S, Gebrekristos H, Grant S, Gu T, Gupta A, Han MK, Hanania NA, Hansel NN, Hayden LP, Hersh CP, Hobbs BD, Hoffman EA, Hogg JC, Hokanson JE, Hoth KF, Hsiao A, Humphries S, Jacobs K, Jacobson FL, Kazerooni EA, Kim V, Kim WJ, Kinney GL, Koegler H, Lutz SM, Lynch DA, MacIntye NR, Make BJ, Marchetti N, Martinez FJ, Maselli DJ, Mathews AM, McCormack MC, McDonald MN, McEvoy CE, Moll M, Molye SS, Murray S, Nath H, Newell JD, Occhipinti M, Paoletti M, Parekh T, Pistolesi M, Pratte KA, Putcha N, Ragland M, Reinhardt JM, Rennard SI, Rosiello RA, Ross JC, Rossiter HB, Ruczinski I, San Jose Estepar R, Sciurba FC, Sieren JC, Singh H, Soler X, Steiner RM, Strand MJ, Stringer WW, Tal-Singer R, Thomashow B, Wan ES, Washko GR, Michael Wells J, Wendt CH, Westney G, Wilson A, Wise RA, Yen A, Young K, Yun J, Silverman EK, Crapo JD, Grenier PA, Vegas S?nchez-Ferrero G, Walsh JW. COPDGene? 2019: Redefining the Diagnosis of Chronic Obstructive Pulmonary Disease. Chronic Obstr Pulm Dis. 2019 Nov; 6(5):384-399. PMID: 31710793; PMCID: PMC7020846.
      Citations: 53     
    135. Dransfield MT, Voelker H, Bhatt SP, Brenner K, Casaburi R, Come CE, Cooper JAD, Criner GJ, Curtis JL, Han MK, Hatipoglu U, Helgeson ES, Jain VV, Kalhan R, Kaminsky D, Kaner R, Kunisaki KM, Lambert AA, Lammi MR, Lindberg S, Make BJ, Martinez FJ, McEvoy C, Panos RJ, Reed RM, Scanlon PD, Sciurba FC, Smith A, Sriram PS, Stringer WW, Weingarten JA, Wells JM, Westfall E, Lazarus SC, Connett JE, BLOCK COPD Trial Group. Metoprolol for the Prevention of Acute Exacerbations of COPD. N Engl J Med. 2019 12 12; 381(24):2304-2314. PMID: 31633896; PMCID: PMC7416529.
      Citations: 26     Fields:    Translation:Humans
    136. Oelsner EC, Ortega VE, Smith BM, Nguyen JN, Manichaikul AW, Hoffman EA, Guo X, Taylor KD, Woodruff PG, Couper DJ, Hansel NN, Martinez FJ, Paine R, Han MK, Cooper C, Dransfield MT, Criner G, Krishnan JA, Bowler R, Bleecker ER, Peters S, Rich SS, Meyers DA, Rotter JI, Barr RG. A Genetic Risk Score Associated with Chronic Obstructive Pulmonary Disease Susceptibility and Lung Structure on Computed Tomography. Am J Respir Crit Care Med. 2019 09 15; 200(6):721-731. PMID: 30925230; PMCID: PMC6775892.
      Citations: 12     Fields:    Translation:Humans
    137. Vasilescu DM, Martinez FJ, Marchetti N, Hatt C, Meldrum CA, Dass C, Tanabe N, Reddy RM, Lagstein A, Ross BD, Labaki WW, Murray S, Meng X, Curtis JL, Hackett TL, Kazerooni EA, Criner GJ, Hogg JC, Han MK, Galb?n CJ. Noninvasive Imaging Biomarker Identifies Small Airway Damage in Severe Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2019 09 01; 200(5):575-581. PMID: 30794432; PMCID: PMC6727153.
      Citations: 42     Fields:    Translation:Humans
    138. Rabe KF, Martinez FJ, Ferguson GT, Wang C, Singh D, Wedzicha JA, Trivedi R, St Rose E, Ballal S, McLaren J, Darken P, Reisner C, Dorinsky P. A phase III study of triple therapy with budesonide/glycopyrrolate/formoterol fumarate metered dose inhaler 320/18/9.6??g and 160/18/9.6??g using co-suspension delivery technology in moderate-to-very severe COPD: The ETHOS study protocol. Respir Med. 2019 Oct - Nov; 158:59-66. PMID: 31605923.
      Citations: 9     Fields:    Translation:HumansCTClinical Trials
    139. Hoesterey D, Das N, Janssens W, Buhr RG, Martinez FJ, Cooper CB, Tashkin DP, Barjaktarevic I. Spirometric indices of early airflow impairment in individuals at risk of developing COPD: Spirometry beyond FEV1/FVC. Respir Med. 2019 09; 156:58-68. PMID: 31437649; PMCID: PMC6768077.
      Citations: 9     Fields:    
    140. Labaki WW, Gu T, Murray S, Curtis JL, Yeomans L, Bowler RP, Barr RG, Comellas AP, Hansel NN, Cooper CB, Barjaktarevic I, Kanner RE, Paine R, McDonald MN, Krishnan JA, Peters SP, Woodruff PG, O'Neal WK, Diao W, He B, Martinez FJ, Standiford TJ, Stringer KA, Han MK. Serum amino acid concentrations and clinical outcomes in smokers: SPIROMICS metabolomics study. Sci Rep. 2019 08 06; 9(1):11367. PMID: 31388056; PMCID: PMC6684630.
      Citations: 7     Fields:    Translation:Humans
    141. Haghighi B, Choi S, Choi J, Hoffman EA, Comellas AP, Newell JD, Lee CH, Barr RG, Bleecker E, Cooper CB, Couper D, Han ML, Hansel NN, Kanner RE, Kazerooni EA, Kleerup EAC, Martinez FJ, O'Neal W, Paine R, Rennard SI, Smith BM, Woodruff PG, Lin CL. Imaging-based clusters in former smokers of the COPD cohort associate with clinical characteristics: the SubPopulations and intermediate outcome measures in COPD study (SPIROMICS). Respir Res. 2019 Jul 15; 20(1):153. PMID: 31307479; PMCID: PMC6631615.
      Citations: 6     Fields:    Translation:Humans
    142. Kaner RJ, Bajwa EK, El-Amine M, Gorina E, Gupta R, Lazarus HM, Luckhardt TR, Mouded M, Posada K, Stauffer J, Tutuncu A, Martinez FJ, Richeldi L. Design of Idiopathic Pulmonary Fibrosis Clinical Trials in the Era of Approved Therapies. Am J Respir Crit Care Med. 2019 07 15; 200(2):133-139. PMID: 30985215.
      Citations: 1     Fields:    Translation:Humans
    143. Pascoe S, Barnes N, Brusselle G, Compton C, Criner GJ, Dransfield MT, Halpin DMG, Han MK, Hartley B, Lange P, Lettis S, Lipson DA, Lomas DA, Martinez FJ, Papi A, Roche N, van der Valk RJP, Wise R, Singh D. Blood eosinophils and treatment response with triple and dual combination therapy in chronic obstructive pulmonary disease: analysis of the IMPACT trial. Lancet Respir Med. 2019 09; 7(9):745-756. PMID: 31281061.
      Citations: 53     Fields:    Translation:HumansCellsCTClinical Trials
    144. Harmouche R, Ash SY, Putman RK, Hunninghake GM, San Jose Estepar R, Martinez FJ, Choi AM, Lynch DA, Hatabu H, Han MK, Bowler RP, Kalhan R, Rosas IO, Washko GR, San Jose Estepar R, COPDGene Investigators. Objectively Measured Chronic Lung Injury?on Chest CT. Chest. 2019 12; 156(6):1149-1159. PMID: 31233744; PMCID: PMC6904856.
      Citations: 4     Fields:    Translation:Humans
    145. Celli BR, Anderson JA, Brook R, Calverley P, Cowans NJ, Crim C, Dixon I, Kim V, Martinez FJ, Morris A, Newby DE, Yates J, Vestbo J. Serum biomarkers and outcomes in patients with moderate COPD: a substudy of the randomised SUMMIT trial. BMJ Open Respir Res. 2019; 6(1):e000431. PMID: 31258919; PMCID: PMC6561388.
      Citations: 14     Translation:Humans
    146. O'Dwyer DN, Ashley SL, Gurczynski SJ, Xia M, Wilke C, Falkowski NR, Norman KC, Arnold KB, Huffnagle GB, Salisbury ML, Han MK, Flaherty KR, White ES, Martinez FJ, Erb-Downward JR, Murray S, Moore BB, Dickson RP. Lung Microbiota Contribute to Pulmonary Inflammation and Disease Progression in Pulmonary Fibrosis. Am J Respir Crit Care Med. 2019 05 01; 199(9):1127-1138. PMID: 30789747; PMCID: PMC6515865.
      Citations: 84     Fields:    Translation:HumansAnimals
    147. Raghu G, Flaherty KR, Lederer DJ, Lynch DA, Colby TV, Myers JL, Groshong SD, Larsen BT, Chung JH, Steele MP, Benzaquen S, Calero K, Case AH, Criner GJ, Nathan SD, Rai NS, Ramaswamy M, Hagmeyer L, Davis JR, Gauhar UA, Pankratz DG, Choi Y, Huang J, Walsh PS, Neville H, Lofaro LR, Barth NM, Kennedy GC, Brown KK, Martinez FJ. Use of a molecular classifier to identify usual interstitial pneumonia in conventional transbronchial lung biopsy samples: a prospective validation study. Lancet Respir Med. 2019 06; 7(6):487-496. PMID: 30948346.
      Citations: 31     Fields:    Translation:Humans
    148. Wells JM, Arenberg DA, Barjaktarevic I, Bhatt SP, Bowler RP, Christenson SA, Couper DJ, Dransfield MT, Han MK, Hoffman EA, Kaner RJ, Kim V, Kleerup E, Martinez FJ, Moore WC, O'Beirne SL, Paine R, Putcha N, Raman SM, Barr RG, Rennard SI, Woodruff PG, Curtis JL. Safety and Tolerability of Comprehensive Research Bronchoscopy in Chronic Obstructive Pulmonary Disease. Results from the SPIROMICS Bronchoscopy Substudy. Ann Am Thorac Soc. 2019 04; 16(4):439-446. PMID: 30653926; PMCID: PMC6441692.
      Citations: 6     Fields:    Translation:HumansCTClinical Trials
    149. Jenkins C, FitzGerald JM, Martinez FJ, Postma DS, Rennard S, van der Molen T, Gardev A, Genofre E, Calverley P. Diagnosis and management of asthma, COPD and asthma-COPD overlap among primary care physicians and respiratory/allergy specialists: A global survey. Clin Respir J. 2019 Jun; 13(6):355-367. PMID: 30825365.
      Citations: 4     Fields:    Translation:Humans
    150. Krishnan JK, Voelker H, Connett JE, Niewoehner DE, Albert RK, Scanlon PD, Criner GJ, Dransfield MT, Han MK, Martinez FJ, COPD Clinical Research Network Investigators. Effect of daily azithromycin therapy and adherence on readmission risk in COPD. Eur Respir J. 2019 03; 53(3). PMID: 30819817.
      Citations: 4     Fields:    Translation:Humans
    151. Norman KC, Freeman CM, Bidthanapally NS, Han MK, Martinez FJ, Curtis JL, Arnold KB. Inference of Cellular Immune Environments in Sputum and Peripheral Blood Associated with Acute Exacerbations of COPD. Cell Mol Bioeng. 2019 Apr; 12(2):165-177. PMID: 31719907; PMCID: PMC6816611.
      Citations: 2     
    152. Labaki WW, Gu T, Murray S, Hatt CR, Ross BD, Martinez CH, Curtis JL, Hoffman EA, Pompe E, Lynch DA, Kazerooni EA, Martinez FJ, Han MK, Galb?n CJ. Reprint of: Voxel-Wise Longitudinal Parametric Response Mapping Analysis of Chest Computed Tomography in Smokers. Acad Radiol. 2019 03; 26(3):306-312. PMID: 30792137; PMCID: PMC6704470.
      Citations: 5     Fields:    
    153. Ghosh S, Anderson WH, Putcha N, Han MK, Curtis JL, Criner GJ, Dransfield MT, Barr RG, Krishnan JA, Lazarus SC, Cooper CB, Paine R, Peters SP, Hansel NN, Martinez FJ, Drummond MB, Current and former investigators of the SPIROMICS sites and reading centers. Alignment of Inhaled Chronic Obstructive Pulmonary Disease Therapies with Published Strategies. Analysis of the Global Initiative for Chronic Obstructive Lung Disease Recommendations in SPIROMICS. Ann Am Thorac Soc. 2019 02; 16(2):200-208. PMID: 30216731; PMCID: PMC6376942.
      Citations: 17     Fields:    Translation:Humans
    154. Garudadri S, Woodruff PG, Han MK, Curtis JL, Barr RG, Bleecker ER, Bowler RP, Comellas A, Cooper CB, Criner G, Dransfield MT, Hansel NN, Paine R, Krishnan JA, Peters SP, Hastie AT, Martinez FJ, O'Neal WK, Couper DJ, Alexis NE, Christenson SA. Systemic Markers of Inflammation in Smokers With Symptoms Despite Preserved?Spirometry in SPIROMICS. Chest. 2019 05; 155(5):908-917. PMID: 30684474; PMCID: PMC6533449.
      Citations: 8     Fields:    Translation:Humans
    155. Criner RN, Labaki WW, Regan EA, Bon JM, Soler X, Bhatt SP, Murray S, Hokanson JE, Silverman EK, Crapo JD, Curtis JL, Martinez FJ, Make BJ, Han MK, Martinez CH, COPDGene? Investigators. Mortality and Exacerbations by Global Initiative for Chronic Obstructive Lung Disease Groups ABCD: 2011 Versus 2017 in the COPDGene? Cohort. Chronic Obstr Pulm Dis. 2019 Jan 10; 6(1):64-73. PMID: 30775425; PMCID: PMC6373581.
      Citations: 16     
    156. Martinez FJ, Abrahams RA, Ferguson GT, Bjermer L, Singh D, Gr?nke L, Vo? F. Effects of baseline symptom burden on treatment response in COPD. Int J Chron Obstruct Pulmon Dis. 2019; 14:181-194. PMID: 30655665; PMCID: PMC6324615.
      Citations: 5     Fields:    Translation:Humans
    157. Criner GJ, Martinez FJ, Aaron S, Anzueto A, Bafadhel M, Barnes PJ, Bourbeau J, Chen R, Ewig J, Fabbri LM, Frith P, Halpin DMG, Han M, Nishimura M, O'Donnell D, Papi A, Pavord I, Rodriguez-Roisin R, Salvi S, Singh D, Sin DD, Stockley R, Vogelmeier CF, Washko G, Wedzicha JA, Celli BR, Agusti A, Montes de Oca M, Roche N, L?pez Varela MV, Vestbo J. Current Controversies in Chronic Obstructive Pulmonary Disease. A Report from the Global Initiative for Chronic Obstructive Lung Disease Scientific Committee. Ann Am Thorac Soc. 2019 01; 16(1):29-39. PMID: 30427736.
      Citations: 2     Fields:    Translation:Humans
    158. Wu X, Kim GH, Salisbury ML, Barber D, Bartholmai BJ, Brown KK, Conoscenti CS, De Backer J, Flaherty KR, Gruden JF, Hoffman EA, Humphries SM, Jacob J, Maher TM, Raghu G, Richeldi L, Ross BD, Schlenker-Herceg R, Sverzellati N, Wells AU, Martinez FJ, Lynch DA, Goldin J, Walsh SLF. Computed Tomographic Biomarkers in Idiopathic Pulmonary Fibrosis. The Future of Quantitative Analysis. Am J Respir Crit Care Med. 2019 01 01; 199(1):12-21. PMID: 29986154.
      Citations: 41     Fields:    Translation:Humans
    159. Bhatt SP, Nath HP, Kim YI, Ramachandran R, Watts JR, Terry NLJ, Sonavane S, Deshmane SP, Woodruff PG, Oelsner EC, Bodduluri S, Han MK, Labaki WW, Michael Wells J, Martinez FJ, Barr RG, Dransfield MT, SPIROMICS investigators. Centrilobular emphysema and coronary artery calcification: mediation analysis in the SPIROMICS cohort. Respir Res. 2018 Dec 18; 19(1):257. PMID: 30563576; PMCID: PMC6299495.
      Citations: 5     Fields:    Translation:Humans
    160. Ryter SW, Rosas IO, Owen CA, Martinez FJ, Choi ME, Lee CG, Elias JA, Choi AMK. Mitochondrial Dysfunction as a Pathogenic Mediator of Chronic Obstructive Pulmonary Disease and Idiopathic Pulmonary Fibrosis. Ann Am Thorac Soc. 2018 12; 15(Suppl 4):S266-S272. PMID: 30759019; PMCID: PMC6944396.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    161. Christenson SA, van den Berge M, Faiz A, Inkamp K, Bhakta N, Bonser LR, Zlock LT, Barjaktarevic IZ, Barr RG, Bleecker ER, Boucher RC, Bowler RP, Comellas AP, Curtis JL, Han MK, Hansel NN, Hiemstra PS, Kaner RJ, Krishnanm JA, Martinez FJ, O'Neal WK, Paine R, Timens W, Wells JM, Spira A, Erle DJ, Woodruff PG. An airway epithelial IL-17A response signature identifies a steroid-unresponsive COPD patient subgroup. J Clin Invest. 2019 01 02; 129(1):169-181. PMID: 30383540; PMCID: PMC6307967.
      Citations: 34     Fields:    Translation:Humans
    162. Pirozzi CS, Gu T, Quibrera PM, Carretta EE, Han MK, Murray S, Cooper CB, Tashkin DP, Kleerup EC, Barjaktarevic I, Hoffman EA, Martinez CH, Christenson SA, Hansel NN, Graham Barr R, Bleecker ER, Ortega VE, Martinez FJ, Kanner RE, Paine R, NHLBI SubPopulations and InteRmediate Outcome Measures In COPD Study (SPIROMICS). Heterogeneous burden of lung disease in smokers with borderline airflow obstruction. Respir Res. 2018 Nov 20; 19(1):223. PMID: 30454050; PMCID: PMC6245799.
      Citations: 4     Fields:    Translation:Humans
    163. Wells JM, Parker MM, Oster RA, Bowler RP, Dransfield MT, Bhatt SP, Cho MH, Kim V, Curtis JL, Martinez FJ, Paine R, O'Neal W, Labaki WW, Kaner RJ, Barjaktarevic I, Han MK, Silverman EK, Crapo JD, Barr RG, Woodruff P, Castaldi PJ, Gaggar A, SPIROMICS and COPDGene Investigators. Elevated circulating MMP-9 is linked to increased COPD exacerbation risk in SPIROMICS and COPDGene. JCI Insight. 2018 11 15; 3(22). PMID: 30429371; PMCID: PMC6302944.
      Citations: 11     Fields:    Translation:Humans
    164. Martinez FJ, Rabe KF, Calverley PMA, Fabbri LM, Sethi S, Pizzichini E, McIvor A, Anzueto A, Alagappan VKT, Siddiqui S, Reisner C, Zetterstrand S, Purkayastha D, Bagul N, Rennard SI, Rom?n J. Determinants of Response to Roflumilast in Severe Chronic Obstructive Pulmonary Disease. Pooled Analysis of Two Randomized Trials. Am J Respir Crit Care Med. 2018 11 15; 198(10):1268-1278. PMID: 29763572.
      Citations: 26     Fields:    Translation:HumansCTClinical Trials
    165. Lu H, Lok AS, Warneke CL, Ahmed S, Torres HA, Martinez F, Suarez-Almazor ME, Foreman JT, Ferrajoli A, Hwang JP. Passive transfer of anti-HBc after intravenous immunoglobulin administration in patients with cancer: a retrospective chart review. Lancet Haematol. 2018 Oct; 5(10):e474-e478. PMID: 30290904; PMCID: PMC6247917.
      Citations: 4     Fields:    Translation:Humans
    166. Martinez FJ, Lederer DJ. Focus on Idiopathic Pulmonary Fibrosis: Advancing Approaches to Diagnosis, Prognosis, and Treatment. Chest. 2018 10; 154(4):978-979. PMID: 30290930.
      Citations: 4     Fields:    
    167. Han MK, Hanania NA, Martinez FJ. Confronting the Challenge of COPD: What Is New in the Approaches to Diagnosis, Treatment, and Patient Outcomes. Chest. 2018 10; 154(4):984-985. PMID: 30290933.
      Citations: 3     Fields:    
    168. Salisbury ML, Gu T, Murray S, Gross BH, Chughtai A, Sayyouh M, Kazerooni EA, Myers JL, Lagstein A, Konopka KE, Belloli EA, Sheth JS, White ES, Holtze C, Martinez FJ, Flaherty KR. Hypersensitivity Pneumonitis: Radiologic Phenotypes Are Associated With Distinct Survival Time and Pulmonary Function Trajectory. Chest. 2019 04; 155(4):699-711. PMID: 30243979; PMCID: PMC6514431.
      Citations: 39     Fields:    Translation:Humans
    169. Haghighi B, Choi S, Choi J, Hoffman EA, Comellas AP, Newell JD, Graham Barr R, Bleecker E, Cooper CB, Couper D, Han ML, Hansel NN, Kanner RE, Kazerooni EA, Kleerup EAC, Martinez FJ, O'Neal W, Rennard SI, Woodruff PG, Lin CL. Imaging-based clusters in current smokers of the COPD cohort associate with clinical characteristics: the SubPopulations and Intermediate Outcome Measures in COPD Study (SPIROMICS). Respir Res. 2018 Sep 18; 19(1):178. PMID: 30227877; PMCID: PMC6145340.
      Citations: 7     Fields:    Translation:Humans
    170. Ferguson GT, Rabe KF, Martinez FJ, Fabbri LM, Wang C, Ichinose M, Bourne E, Ballal S, Darken P, DeAngelis K, Dorinsky P, Reisner C, Aurivillius M. Triple therapy with budesonide/glycopyrrolate/formoterol fumarate with co-suspension delivery technology versus dual therapies in chronic obstructive pulmonary disease (KRONOS): a double-blind, parallel-group, multicentre, phase 3 randomised controlled trial. Lancet Respir Med. 2018 10; 6(10):747-758. PMID: 30232048.
      Citations: 85     Fields:    Translation:HumansCTClinical Trials
    171. Adamson PD, Anderson JA, Brook RD, Calverley PMA, Celli BR, Cowans NJ, Crim C, Dixon IJ, Martinez FJ, Newby DE, Yates JC, Mills NL, Vestbo J. Cardiac Troponin I and Cardiovascular Risk in Patients With Chronic Obstructive Pulmonary?Disease. J Am Coll Cardiol. 2018 09 04; 72(10):1126-1137. PMID: 30165984; PMCID: PMC6119211.
      Citations: 15     Fields:    Translation:Humans
    172. Byrd JB, Newby DE, Anderson JA, Calverley PMA, Celli BR, Cowans NJ, Crim C, Martinez FJ, Yates J, Brook RD, SUMMIT Investigators, Vestbo J. Blood pressure, heart rate, and mortality in chronic obstructive pulmonary disease: the SUMMIT trial. Eur Heart J. 2018 09 01; 39(33):3128-3134. PMID: 30101300; PMCID: PMC7263699.
      Citations: 9     Fields:    Translation:Humans
    173. Salisbury ML, Gross BH, Chughtai A, Sayyouh M, Kazerooni EA, Bartholmai BJ, Xia M, Murray S, Myers JL, Lagstein A, Konopka KE, Belloli EA, Sheth JS, White ES, Holtze C, Flaherty KR, Martinez FJ. Development and validation of a radiological diagnosis model for hypersensitivity pneumonitis. Eur Respir J. 2018 08; 52(2). PMID: 29946001; PMCID: PMC6181129.
      Citations: 14     Fields:    Translation:Humans
    174. Maselli DJ, Hardin M, Christenson SA, Hanania NA, Hersh CP, Adams SG, Anzueto A, Peters JI, Han MK, Martinez FJ. Clinical Approach to the Therapy of Asthma-COPD Overlap. Chest. 2019 01; 155(1):168-177. PMID: 30077690; PMCID: PMC6688980.
      Citations: 14     Fields:    Translation:Humans
    175. Li X, Ortega VE, Ampleford EJ, Graham Barr R, Christenson SA, Cooper CB, Couper D, Dransfield MT, Han MLK, Hansel NN, Hoffman EA, Kanner RE, Kleerup EC, Martinez FJ, Paine R, Woodruff PG, Hawkins GA, Bleecker ER, Meyers DA, SPIROMICS Research Group. Genome-wide association study of lung function and clinical implication in heavy smokers. BMC Med Genet. 2018 08 01; 19(1):134. PMID: 30068317; PMCID: PMC6090900.
      Citations: 16     Fields:    Translation:Humans
    176. Sidhaye VK, Nishida K, Martinez FJ. Precision medicine in COPD: where are we and where do we need to go? Eur Respir Rev. 2018 Sep 30; 27(149). PMID: 30068688; PMCID: PMC6156790.
      Citations: 24     Fields:    Translation:Humans
    177. Labaki WW, Gu T, Murray S, Hatt CR, Ross BD, Martinez CH, Curtis JL, Hoffman EA, Pompe E, Lynch DA, Kazerooni EA, Martinez FJ, Han MK, Galb?n CJ. Voxel-Wise Longitudinal Parametric Response Mapping Analysis of Chest Computed Tomography in Smokers. Acad Radiol. 2019 02; 26(2):217-223. PMID: 30055897; PMCID: PMC6340741.
      Citations: 22     Fields:    Translation:Humans
    178. Han MK, Tayob N, Murray S, Woodruff PG, Curtis JL, Kim V, Criner G, Galban CJ, Ross BD, Hoffman EA, Lynch DA, Kazerooni E, Martinez FJ, COPDGene and SPIROMICS Investigators. Association between Emphysema and Chronic Obstructive Pulmonary Disease Outcomes in the COPDGene and SPIROMICS Cohorts: A Post Hoc Analysis of Two Clinical Trials. Am J Respir Crit Care Med. 2018 07 15; 198(2):265-267. PMID: 29485901; PMCID: PMC6058986.
      Citations: 13     Fields:    Translation:HumansCTClinical Trials
    179. Jin M, Lee EC, Ra SW, Fishbane N, Tam S, Criner GJ, Woodruff PG, Lazarus SC, Albert R, Connett JE, Han MK, Martinez FJ, Aaron SD, Reed RM, Man SFP, Leung JM, Sin DD. Relationship of Absolute Telomere Length With Quality of Life, Exacerbations, and Mortality in COPD. Chest. 2018 08; 154(2):266-273. PMID: 30017346.
      Citations: 11     Fields:    Translation:HumansCells
    180. Kunisaki KM, Dransfield MT, Anderson JA, Brook RD, Calverley PMA, Celli BR, Crim C, Hartley BF, Martinez FJ, Newby DE, Pragman AA, Yates JC, Niewoehner DE, SUMMIT Investigators, Vestbo J. Exacerbations of Chronic Obstructive Pulmonary Disease and Cardiac Events. A Post Hoc Cohort Analysis from the SUMMIT Randomized Clinical Trial. Am J Respir Crit Care Med. 2018 07 01; 198(1):51-57. PMID: 29442524; PMCID: PMC6913068.
      Citations: 62     Fields:    Translation:Humans
    181. Burkes RM, Gassett AJ, Ceppe AS, Anderson W, O'Neal WK, Woodruff PG, Krishnan JA, Barr RG, Han MK, Martinez FJ, Comellas AP, Lambert AA, Kaufman JD, Dransfield MT, Wells JM, Kanner RE, Paine R, Bleecker ER, Paulin LM, Hansel NN, Drummond MB, Current and former investigators of the SPIROMICS sites and reading centers. Rural Residence and Chronic Obstructive Pulmonary Disease Exacerbations. Analysis of the SPIROMICS Cohort. Ann Am Thorac Soc. 2018 Jul; 15(7):808-816. PMID: 29584453; PMCID: PMC6207115.
      Citations: 9     Fields:    
    182. Martinez FJ, Han MK, Allinson JP, Barr RG, Boucher RC, Calverley PMA, Celli BR, Christenson SA, Crystal RG, Freeman CM, Groenke L, Hoffman EA, Kesimer M, Kostikas K, Paine R, Rafii S, Rennard SI, Segal LN, Shaykhiev R, Stevenson C, Tal-Singer R, Woodruff PG, Curtis JL, Wedzicha JA, Fager?s M, Vestbo J. At the Root: Defining and Halting Progression of Early Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2018 06 15; 197(12):1540-1551. PMID: 29406779; PMCID: PMC6006401.
      Citations: 77     Fields:    Translation:Humans
    183. Celli B, Anderson JA, Brook R, Calverley P, Crim C, Holmes AP, Martinez FJ, Newby DE, Yates J, SUMMIT Investigators, Vestbo J. Long-Acting ?-Agonist/Inhaled Corticosteroid in Patients with Chronic Obstructive Pulmonary Disease with Cardiovascular Disease or Risk: A Factorial Analysis of the SUMMIT Clinical Trial. Am J Respir Crit Care Med. 2018 06 15; 197(12):1641-1644. PMID: 29412688.
      Citations:    Fields:    Translation:Humans
    184. Leidy NK, Martinez FJ, Malley KG, Mannino DM, Han MK, Bacci ED, Brown RW, Houfek JF, Labaki WW, Make BJ, Meldrum CA, Quezada W, Rennard S, Thomashow B, Yawn BP. Can CAPTURE be used to identify undiagnosed patients with mild-to-moderate COPD likely to benefit from treatment? Int J Chron Obstruct Pulmon Dis. 2018; 13:1901-1912. PMID: 29942123; PMCID: PMC6005334.
      Citations: 4     Fields:    Translation:Humans
    185. Labaki WW, Xia M, Murray S, Curtis JL, Barr RG, Bhatt SP, Bleecker ER, Hansel NN, Cooper CB, Dransfield MT, Wells JM, Hoffman EA, Kanner RE, Paine R, Ortega VE, Peters SP, Krishnan JA, Bowler RP, Couper DJ, Woodruff PG, Martinez FJ, Martinez CH, Han MK. NT-proBNP in stable COPD and future exacerbation risk: Analysis of the SPIROMICS cohort. Respir Med. 2018 07; 140:87-93. PMID: 29957287; PMCID: PMC6084793.
      Citations: 6     Fields:    Translation:Humans
    186. Ash SY, Harmouche R, Ross JC, Diaz AA, Rahaghi FN, Vegas Sanchez-Ferrero G, Putman RK, Hunninghake GM, Onieva Onieva J, Martinez FJ, Choi AM, Bowler RP, Lynch DA, Hatabu H, Bhatt SP, Dransfield MT, Wells JM, Rosas IO, San Jose Estepar R, Washko GR, COPDGene Investigators. Interstitial Features at Chest CT Enhance the Deleterious Effects of Emphysema in the COPDGene Cohort. Radiology. 2018 08; 288(2):600-609. PMID: 29869957; PMCID: PMC6069608.
      Citations: 9     Fields:    Translation:Humans
    187. Segal LN, Martinez FJ. Chronic obstructive pulmonary disease subpopulations and phenotyping. J Allergy Clin Immunol. 2018 06; 141(6):1961-1971. PMID: 29884286; PMCID: PMC5996762.
      Citations: 14     Fields:    Translation:Humans
    188. Putcha N, Fawzy A, Paul GG, Lambert AA, Psoter KJ, Sidhaye VK, Woo J, Wells JM, Labaki WW, Doerschuk CM, Kanner RE, Han MK, Martinez C, Paulin LM, Martinez FJ, Wise RA, O'Neal WK, Barr RG, Hansel NN, SPIROMICS investigators. Anemia and Adverse Outcomes in a Chronic Obstructive Pulmonary Disease Population with a High Burden of Comorbidities. An Analysis from SPIROMICS. Ann Am Thorac Soc. 2018 06; 15(6):710-717. PMID: 30726108; PMCID: PMC6207135.
      Citations: 10     Fields:    Translation:Humans
    189. Cazzola M, Calzetta L, Barnes PJ, Criner GJ, Martinez FJ, Papi A, Gabriella Matera M. Efficacy and safety profile of xanthines in COPD: a network meta-analysis. Eur Respir Rev. 2018 Jun 30; 27(148). PMID: 29720510; PMCID: PMC9488859.
      Citations: 12     Fields:    Translation:Humans
    190. Dransfield MT, McAllister DA, Anderson JA, Brook RD, Calverley PMA, Celli BR, Crim C, Gallot N, Martinez FJ, Scanlon PD, Yates J, Newby DE, SUMMIT Investigators, Vestbo J. ?-Blocker Therapy and Clinical Outcomes in Patients with Moderate Chronic Obstructive Pulmonary Disease and Heightened Cardiovascular Risk. An Observational Substudy of SUMMIT. Ann Am Thorac Soc. 2018 05; 15(5):608-614. PMID: 29406772.
      Citations: 5     Fields:    Translation:Humans
    191. Labaki WW, Martinez FJ. Time to Understand the Infrequency of the Frequent Exacerbator Phenotype in COPD. Chest. 2018 05; 153(5):1087-1088. PMID: 29731034.
      Citations: 1     Fields:    Translation:Humans
    192. Lipson DA, Barnhart F, Brealey N, Brooks J, Criner GJ, Day NC, Dransfield MT, Halpin DMG, Han MK, Jones CE, Kilbride S, Lange P, Lomas DA, Martinez FJ, Singh D, Tabberer M, Wise RA, Pascoe SJ, IMPACT Investigators. Once-Daily Single-Inhaler Triple versus Dual Therapy in Patients with COPD. N Engl J Med. 2018 May 03; 378(18):1671-1680. PMID: 29668352.
      Citations: 266     Fields:    Translation:HumansCTClinical Trials
    193. Putcha N, Paul GG, Azar A, Wise RA, O'Neal WK, Dransfield MT, Woodruff PG, Curtis JL, Comellas AP, Drummond MB, Lambert AA, Paulin LM, Fawzy A, Kanner RE, Paine R, Han MK, Martinez FJ, Bowler RP, Barr RG, Hansel NN, SPIROMICS investigators. Lower serum IgA is associated with COPD exacerbation risk in SPIROMICS. PLoS One. 2018; 13(4):e0194924. PMID: 29649230; PMCID: PMC5896903.
      Citations: 9     Fields:    Translation:Humans
    194. Arora K, Kelley J, Martinez F, Tholpady A. Preoperative autologous blood collection before bone marrow harvests in haploidentical related donors: is it justified? Transfusion. 2018 07; 58(7):1618-1625. PMID: 29577348.
      Citations: 1     Fields:    Translation:Humans
    195. Krishnan JK, Martinez FJ. Lung function trajectories and chronic obstructive pulmonary disease: current understanding and knowledge gaps. Curr Opin Pulm Med. 2018 03; 24(2):124-129. PMID: 29206658.
      Citations: 9     Fields:    Translation:Humans
    196. Leitao Filho FS, Ra SW, Mattman A, Schellenberg RS, Criner GJ, Woodruff PG, Lazarus SC, Albert R, Connett JE, Han MK, Martinez FJ, Leung JM, Paul Man SF, Aaron SD, Reed RM, Sin DD, Canadian Respiratory Research Network (CRRN). Serum IgG subclass levels and risk of exacerbations and hospitalizations in patients with COPD. Respir Res. 2018 02 14; 19(1):30. PMID: 29444682; PMCID: PMC5813358.
      Citations: 13     Fields:    Translation:Humans
    197. Ash SY, Harmouche R, Putman RK, Ross JC, Martinez FJ, Choi AM, Bowler RP, Regan EA, Curtis JL, Han MK, Boucher RC, O'Neal WK, Hatabu H, Lynch DA, Rosas IO, Hunninghake GM, San Jose Estepar R, Washko GR, COPDGene Investigators. Association between acute respiratory disease events and the MUC5B promoter polymorphism in smokers. Thorax. 2018 11; 73(11):1071-1074. PMID: 29440587; PMCID: PMC6089672.
      Citations: 4     Fields:    Translation:HumansCells
    198. Bhatt SP, Anderson JA, Brook RD, Calverley PMA, Celli BR, Cowans NJ, Crim C, Newby DE, Yates JC, Dransfield MT, Martinez FJ, Vestbo J. Cigarette smoking and response to inhaled corticosteroids in COPD. Eur Respir J. 2018 01; 51(1). PMID: 29348179.
      Citations: 7     Fields:    Translation:Humans
    199. Smith BM, Traboulsi H, Austin JHM, Manichaikul A, Hoffman EA, Bleecker ER, Cardoso WV, Cooper C, Couper DJ, Dashnaw SM, Guo J, Han MK, Hansel NN, Hughes EW, Jacobs DR, Kanner RE, Kaufman JD, Kleerup E, Lin CL, Liu K, Lo Cascio CM, Martinez FJ, Nguyen JN, Prince MR, Rennard S, Rich SS, Simon L, Sun Y, Watson KE, Woodruff PG, Baglole CJ, Barr RG, MESA Lung and SPIROMICS investigators. Human airway branch variation and chronic obstructive pulmonary disease. Proc Natl Acad Sci U S A. 2018 01 30; 115(5):E974-E981. PMID: 29339516; PMCID: PMC5798356.
      Citations: 31     Fields:    Translation:Humans
    200. Martinez FJ, Han M, Leidy N, Make B, Mannino DM, Rennard SI, Thomashow BM, Yawn BP, High-Risk-COPD Screening Study Group. Reply to Londhe et al.: CAPTURE: A Screening Tool for Chronic Obstructive Pulmonary Disease or Obstructive Airway Disease? Am J Respir Crit Care Med. 2018 01 15; 197(2):272-274. PMID: 28723257; PMCID: PMC5955020.
      Citations:    Fields:    Translation:HumansPHPublic Health
    201. Calverley PMA, Anderson JA, Brook RD, Crim C, Gallot N, Kilbride S, Martinez FJ, Yates J, Newby DE, Wise R, SUMMIT (Study to Understand Mortality and Morbidity) Investigators, Vestbo J, Celli BR. Fluticasone Furoate, Vilanterol, and Lung Function Decline in Patients with Moderate Chronic Obstructive Pulmonary Disease and Heightened Cardiovascular Risk. Am J Respir Crit Care Med. 2018 01 01; 197(1):47-55. PMID: 28737971.
      Citations: 20     Fields:    Translation:Humans
    202. Yusen RD, Criner GJ, Sternberg AL, Au DH, Fuhlbrigge AL, Albert RK, Casaburi R, Stoller JK, Harrington KF, Cooper JAD, Diaz P, Gay S, Kanner R, MacIntyre N, Martinez FJ, Piantadosi S, Sciurba F, Shade D, Stibolt T, Tonascia J, Wise R, Bailey WC, LOTT Research Group *, LOTT Research Group. The Long-Term Oxygen Treatment Trial for Chronic Obstructive Pulmonary Disease: Rationale, Design, and Lessons Learned. Ann Am Thorac Soc. 2018 01; 15(1):89-101. PMID: 29087741; PMCID: PMC5822416.
      Citations: 3     Fields:    Translation:HumansCTClinical Trials
    203. Labaki WW, Martinez CH, Martinez FJ, Ross BD, Washko GR, Barr RG, Regan EA, Coxson HO, Hoffman EA, Newell JD, Curran-Everett D, Hogg JC, Crapo JD, Lynch DA, Kazerooni EA, Han MK, Galb?n CJ. The Role of Chest Computed Tomography in the Evaluation and Management of the Patient with Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2017 12 01; 196(11):1372-1379. PMID: 28661698; PMCID: PMC5736976.
      Citations: 35     Fields:    Translation:Humans
    204. Hastie AT, Martinez FJ, Curtis JL, Doerschuk CM, Hansel NN, Christenson S, Putcha N, Ortega VE, Li X, Barr RG, Carretta EE, Couper DJ, Cooper CB, Hoffman EA, Kanner RE, Kleerup E, O'Neal WK, Paine R, Peters SP, Alexis NE, Woodruff PG, Han MK, Meyers DA, Bleecker ER, SPIROMICS investigators. Association of sputum and blood eosinophil concentrations with clinical measures of COPD severity: an analysis of the SPIROMICS cohort. Lancet Respir Med. 2017 12; 5(12):956-967. PMID: 29146301; PMCID: PMC5849066.
      Citations: 78     Fields:    Translation:HumansCells
    205. Choi S, Haghighi B, Choi J, Hoffman EA, Comellas AP, Newell JD, Wenzel SE, Castro M, Fain SB, Jarjour NN, Schiebler ML, Barr RG, Han MK, Bleecker ER, Cooper CB, Couper D, Hansel N, Kanner RE, Kazerooni EA, Kleerup EAC, Martinez FJ, O'Neal WK, Woodruff PG, Lin CL. Differentiation of quantitative CT imaging phenotypes in asthma versus COPD. BMJ Open Respir Res. 2017; 4(1):e000252. PMID: 29435345; PMCID: PMC5687530.
      Citations: 9     
    206. Rosas IO, Goldberg HJ, Collard HR, El-Chemaly S, Flaherty K, Hunninghake GM, Lasky JA, Lederer DJ, Machado R, Martinez FJ, Maurer R, Teller D, Noth I, Peters E, Raghu G, Garcia JGN, Choi AMK. A Phase II Clinical Trial of Low-Dose Inhaled Carbon Monoxide in Idiopathic Pulmonary Fibrosis. Chest. 2018 01; 153(1):94-104. PMID: 29100885; PMCID: PMC6026220.
      Citations: 27     Fields:    Translation:HumansCTClinical Trials
    207. Anderson WH, Ha JW, Couper DJ, O'Neal WK, Barr RG, Bleecker ER, Carretta EE, Cooper CB, Doerschuk CM, Drummond MB, Han MK, Hansel NN, Kim V, Kleerup EC, Martinez FJ, Rennard SI, Tashkin D, Woodruff PG, Paine R, Curtis JL, Kanner RE, SPIROMICS Research Group. Variability in objective and subjective measures affects baseline values in studies of patients with COPD. PLoS One. 2017; 12(9):e0184606. PMID: 28934249; PMCID: PMC5608200.
      Citations: 9     Fields:    Translation:Humans
    208. Salisbury ML, Myers JL, Belloli EA, Kazerooni EA, Martinez FJ, Flaherty KR. Diagnosis and Treatment of Fibrotic Hypersensitivity Pneumonia. Where We Stand and Where We Need to Go. Am J Respir Crit Care Med. 2017 09 15; 196(6):690-699. PMID: 28002680; PMCID: PMC5620675.
      Citations: 52     Fields:    Translation:Humans
    209. Salisbury ML, Tolle LB, Xia M, Murray S, Tayob N, Nambiar AM, Schmidt SL, Lagstein A, Myers JL, Gross BH, Kazerooni EA, Sundaram B, Chughtai AR, Martinez FJ, Flaherty KR. Possible UIP pattern on high-resolution computed tomography is associated with better survival than definite UIP in IPF patients. Respir Med. 2017 10; 131:229-235. PMID: 28947036; PMCID: PMC5679475.
      Citations: 10     Fields:    Translation:Humans
    210. Martinez CH, Li SX, Hirzel AJ, Stolberg VR, Alexis NE, Barr RG, Bleecker ER, Carretta EE, Christenson SA, Cooper CB, Couper DJ, Doerschuk CM, Han MK, Hansel NN, Hastie AT, Hoffman EA, Kaner RJ, Martinez FJ, Meyers DA, O'Neal WK, Paine R, Putcha N, Rennard SI, Woodruff PG, Zeidler M, Curtis JL, Freeman CM, SPIROMICS Investigators. Alveolar eosinophilia in current smokers with chronic obstructive pulmonary disease in the SPIROMICS cohort. J Allergy Clin Immunol. 2018 01; 141(1):429-432. PMID: 28916185; PMCID: PMC5758424.
      Citations: 3     Fields:    Translation:Humans
    211. Kesimer M, Ford AA, Ceppe A, Radicioni G, Cao R, Davis CW, Doerschuk CM, Alexis NE, Anderson WH, Henderson AG, Barr RG, Bleecker ER, Christenson SA, Cooper CB, Han MK, Hansel NN, Hastie AT, Hoffman EA, Kanner RE, Martinez F, Paine R, Woodruff PG, O'Neal WK, Boucher RC. Airway Mucin Concentration as a Marker of Chronic Bronchitis. N Engl J Med. 2017 09 07; 377(10):911-922. PMID: 28877023; PMCID: PMC5706541.
      Citations:    
    212. Hatt CR, Murray S, Hoffman EA, Kazerooni EA, Martinez FJ, Han MK, Fern?ndez-Baldera A, Galb?n CJ. Correcting Nonpathological Variation in Longitudinal Parametric Response Maps of CT Scans in COPD Subjects: SPIROMICS. Tomography. 2017 Sep; 3(3):138-145. PMID: 29457137; PMCID: PMC5812694.
      Citations:    Fields:    
    213. Nathan SD, Martinez FJ. Pitfalls in developing new compounds for idiopathic pulmonary fibrosis. Curr Opin Pulm Med. 2017 09; 23(5):426-431. PMID: 28771451.
      Citations:    Fields:    Translation:Humans
    214. Reisner C, Fabbri LM, Kerwin EM, Fogarty C, Spangenthal S, Rabe KF, Ferguson GT, Martinez FJ, Donohue JF, Darken P, St Rose E, Orevillo C, Strom S, Fischer T, Golden M, Dwivedi S. Erratum to: A randomized, seven-day study to assess the efficacy and safety of a glycopyrrolate/formoterol fumarate fixed-dose combination metered dose inhaler using novel Co-Suspension? Delivery Technology in patients with moderate-to-very severe chronic obstructive pulmonary disease. Respir Res. 2017 08 21; 18(1):158. PMID: 28826397; PMCID: PMC5563904.
      Citations:    Fields:    
    215. Crim C, Calverley PMA, Anderson JA, Holmes AP, Kilbride S, Martinez FJ, Brook RD, Newby DE, Yates JC, SUMMIT investigators, Celli BR, Vestbo J. Pneumonia risk with inhaled fluticasone furoate and vilanterol in COPD patients with moderate airflow limitation: The SUMMIT trial. Respir Med. 2017 10; 131:27-34. PMID: 28947039.
      Citations: 9     Fields:    Translation:Humans
    216. Martinez FJ, Fabbri LM, Ferguson GT, Orevillo C, Darken P, Martin UJ, Reisner C. Baseline Symptom Score Impact on Benefits of Glycopyrrolate/Formoterol Metered Dose Inhaler in COPD. Chest. 2017 12; 152(6):1169-1178. PMID: 28720336.
      Citations: 13     Fields:    Translation:HumansCTClinical Trials
    217. Huang Y, Ma SF, Espindola MS, Vij R, Oldham JM, Huffnagle GB, Erb-Downward JR, Flaherty KR, Moore BB, White ES, Zhou T, Li J, Lussier YA, Han MK, Kaminski N, Garcia JGN, Hogaboam CM, Martinez FJ, Noth I, COMET-IPF Investigators. Microbes Are Associated with Host Innate Immune Response in Idiopathic Pulmonary Fibrosis. Am J Respir Crit Care Med. 2017 07 15; 196(2):208-219. PMID: 28157391; PMCID: PMC5519968.
      Citations: 62     Fields:    Translation:HumansCells
    218. Rabe KF, Calverley PMA, Fabbri LM, Martinez FJ. Effect of roflumilast in patients with severe COPD and a history of hospitalisation. Eur Respir J. 2017 07; 50(1). PMID: 28679611.
      Citations: 11     Fields:    Translation:Humans
    219. Tashkin DP, Martinez FJ, Fogarty C, Gotfried M, Denenberg M, Gottschlich G, Donohue JF, Orevillo C, Darken P, St Rose E, Strom S, Fischer T, Golden M, Reisner C, Rodriguez-Roisin R. Corrigendum to "A multicenter, randomized, double-blind dose-ranging study of glycopyrrolate/formoterol fumarate fixed-dose combination metered dose inhaler compared to the monocomponents and open-label tiotropium dry powder inhaler in patients with moderate-to-severe COPD" [Respir. Med. 120 November 2016 16-24]. Respir Med. 2017 08; 129:164. PMID: 28732826.
      Citations:    Fields:    
    220. Han MK, Quibrera PM, Carretta EE, Barr RG, Bleecker ER, Bowler RP, Cooper CB, Comellas A, Couper DJ, Curtis JL, Criner G, Dransfield MT, Hansel NN, Hoffman EA, Kanner RE, Krishnan JA, Martinez CH, Pirozzi CB, O'Neal WK, Rennard S, Tashkin DP, Wedzicha JA, Woodruff P, Paine R, Martinez FJ, SPIROMICS investigators. Frequency of exacerbations in patients with chronic obstructive pulmonary disease: an analysis of the SPIROMICS cohort. Lancet Respir Med. 2017 08; 5(8):619-626. PMID: 28668356; PMCID: PMC5558856.
      Citations: 94     Fields:    Translation:Humans
    221. Galli JA, Panetta NL, Gaeckle N, Martinez FJ, Moore B, Moore T, Courey A, Flaherty K, Criner GJ, COMET investigators. Pneumothorax After Transbronchial Biopsy in Pulmonary Fibrosis: Lessons from the Multicenter COMET Trial. Lung. 2017 Oct; 195(5):537-543. PMID: 28623539; PMCID: PMC5693691.
      Citations: 4     Fields:    Translation:Humans
    222. Ra SW, Sze MA, Lee EC, Tam S, Oh Y, Fishbane N, Criner GJ, Woodruff PG, Lazarus SC, Albert R, Connett JE, Han MK, Martinez FJ, Aaron SD, Reed RM, Man SFP, Sin DD, Canadian Respiratory Research Network. Azithromycin and risk of COPD exacerbations in patients with and without Helicobacter pylori. Respir Res. 2017 05 30; 18(1):109. PMID: 28558695; PMCID: PMC5450077.
      Citations: 1     Fields:    Translation:HumansCells
    223. Ash SY, Harmouche R, Putman RK, Ross JC, Diaz AA, Hunninghake GM, Onieva Onieva J, Martinez FJ, Choi AM, Lynch DA, Hatabu H, Rosas IO, San Jose Estepar R, Washko GR, COPDGene Investigators. Clinical and Genetic Associations of Objectively Identified Interstitial Changes in?Smokers. Chest. 2017 10; 152(4):780-791. PMID: 28506611; PMCID: PMC5812756.
      Citations: 14     Fields:    Translation:HumansCells
    224. Martinez CH, Murray S, Barr RG, Bleecker E, Bowler RP, Christenson SA, Comellas AP, Cooper CB, Couper D, Criner GJ, Curtis JL, Dransfield MT, Hansel NN, Hoffman EA, Kanner RE, Kleerup E, Krishnan JA, Lazarus SC, Leidy NK, O'Neal W, Martinez FJ, Paine R, Rennard SI, Tashkin DP, Woodruff PG, Han MK, Subpopulations and Intermediate Outcome Measures in COPD Study Investigators. Respiratory Symptoms Items from the COPD Assessment Test Identify Ever-Smokers with Preserved Lung Function at Higher Risk for Poor Respiratory Outcomes. An Analysis of the Subpopulations and Intermediate Outcome Measures in COPD Study Cohort. Ann Am Thorac Soc. 2017 May; 14(5):636-642. PMID: 28459622; PMCID: PMC5427740.
      Citations: 15     Fields:    Translation:Humans
    225. Martinez FJ, Flaherty KR. Comprehensive and Individualized Patient Care in Idiopathic Pulmonary Fibrosis: Refining Approaches to Diagnosis, Prognosis, and Treatment. Chest. 2017 05; 151(5):1173-1174. PMID: 28483105.
      Citations: 4     Fields:    Translation:Humans
    226. Won Ra S, Mattman A, Schellenberg RS, Fishbane N, Criner GJ, Woodruff PG, Lazarus SC, Albert R, Connett JE, Han MK, Martinez FJ, Leung JM, Man SFP, Aaron SD, Reed RM, Sin DD, Leitao Filho FS. Serum IgG and risk of exacerbations and hospitalizations in chronic obstructive pulmonary disease. J Allergy Clin Immunol. 2017 10; 140(4):1164-1167.e6. PMID: 28456620.
      Citations: 9     Fields:    Translation:Humans
    227. O'Dwyer DN, Norman KC, Xia M, Huang Y, Gurczynski SJ, Ashley SL, White ES, Flaherty KR, Martinez FJ, Murray S, Noth I, Arnold KB, Moore BB. The peripheral blood proteome signature of idiopathic pulmonary fibrosis is distinct from normal and is associated with novel immunological processes. Sci Rep. 2017 04 25; 7:46560. PMID: 28440314; PMCID: PMC5404506.
      Citations: 24     Fields:    Translation:HumansCTClinical Trials
    228. Brook RD, Anderson JA, Calverley PM, Celli BR, Crim C, Denvir MA, Magder S, Martinez FJ, Rajagopalan S, Yates J, Newby DE, SUMMIT Investigators, Vestbo J. Cardiovascular outcomes with an inhaled beta2-agonist/corticosteroid in patients with COPD at high cardiovascular risk. Heart. 2017 10; 103(19):1536-1542. PMID: 28416587; PMCID: PMC5629944.
      Citations: 17     Fields:    Translation:Humans
    229. Sethi S, Fogarty C, Hanania NA, Martinez FJ, Rennard S, Fries M, Orevillo C, Darken P, St Rose E, Strom S, Fischer T, Golden M, Dwivedi S, Reisner C. Erratum: Erratum: Efficacy of Formoterol Fumarate Delivered by Metered Dose Inhaler Using Co-Suspension? Delivery Technology Versus Foradil? Aerolizer? in Moderate-To-Severe COPD: A Randomized, Dose-Ranging Study. Chronic Obstr Pulm Dis. 2017 Apr 15; 4(3):258. PMID: 28853450; PMCID: PMC5556917.
      Citations:    
    230. Quezada WA, Whippo BA, Jellen PA, Leidy NK, Mannino DM, Kim KJ, Han MK, Houfek JF, Make B, Malley KG, Meldrum CA, Rennard SI, Yawn BP, Martinez FJ, Thomashow BM, High-Risk-COPD Screening Study Group(*). How Well Does CAPTURE Translate?: An Exploratory Analysis of a COPD Case-Finding Method for?Spanish-Speaking Patients. Chest. 2017 10; 152(4):761-770. PMID: 28414029; PMCID: PMC5812773.
      Citations: 1     Fields:    Translation:HumansCTClinical Trials
    231. Martinez FJ, Anderson JA, Brook RD, Celli BR, Cowans NJ, Crim C, Dransfield M, Kilbride S, Yates J, Newby DE, Niewoehner D, Calverley PM, SUMMIT Investigators, Vestbo J. Effect of Fluticasone Furoate and Vilanterol on Exacerbations of Chronic Obstructive Pulmonary Disease in Patients with Moderate Airflow Obstruction. Am J Respir Crit Care Med. 2017 04 01; 195(7):881-888. PMID: 27767328.
      Citations: 17     Fields:    Translation:Humans
    232. Salisbury ML, Lynch DA, van Beek EJ, Kazerooni EA, Guo J, Xia M, Murray S, Anstrom KJ, Yow E, Martinez FJ, Hoffman EA, Flaherty KR, IPFnet Investigators. Idiopathic Pulmonary Fibrosis: The Association between the Adaptive Multiple Features Method and Fibrosis Outcomes. Am J Respir Crit Care Med. 2017 04 01; 195(7):921-929. PMID: 27767347; PMCID: PMC5387708.
      Citations: 35     Fields:    Translation:Humans
    233. Martinez FJ, Mannino D, Leidy NK, Malley KG, Bacci ED, Barr RG, Bowler RP, Han MK, Houfek JF, Make B, Meldrum CA, Rennard S, Thomashow B, Walsh J, Yawn BP, High-Risk-COPD Screening Study Group *. A New Approach for Identifying Patients with Undiagnosed Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2017 03 15; 195(6):748-756. PMID: 27783539; PMCID: PMC5363964.
      Citations: 31     Fields:    Translation:Humans
    234. Vogelmeier CF, Criner GJ, Martinez FJ, Anzueto A, Barnes PJ, Bourbeau J, Celli BR, Chen R, Decramer M, Fabbri LM, Frith P, Halpin DM, Nishimura M, Rodriguez-Roisin R, Sin DD, Singh D, Stockley R, Wedzicha JA, L?pez Varela MV, Roche N, Vestbo J, Agusti A. Global Strategy for the Diagnosis, Management and Prevention of Chronic Obstructive Lung Disease 2017 Report: GOLD Executive Summary. Respirology. 2017 04; 22(3):575-601. PMID: 28150362.
      Citations: 132     Fields:    Translation:Humans
    235. Vogelmeier CF, Criner GJ, Anzueto A, Barnes PJ, Bourbeau J, Celli BR, Chen R, Decramer M, Fabbri LM, Frith P, Halpin DM, Nishimura M, Rodriguez-Roisin R, Sin DD, Singh D, Stockley R, Wedzicha JA, Martinez FJ, L?pez Varela MV, Roche N, Vestbo J, Agusti A. Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease 2017 Report: GOLD Executive Summary. Eur Respir J. 2017 03; 49(3). PMID: 28182564.
      Citations: 218     Fields:    Translation:Humans
    236. Vogelmeier CF, Criner GJ, Martinez FJ, Anzueto A, Barnes PJ, Bourbeau J, Celli BR, Chen R, Decramer M, Fabbri LM, Frith P, Halpin DM, Nishimura M, Rodriguez-Roisin R, Sin DD, Singh D, Stockley R, Wedzicha JA, L?pez Varela MV, Roche N, Vestbo J, Agust? A. Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease 2017 Report. GOLD Executive Summary. Am J Respir Crit Care Med. 2017 03 01; 195(5):557-582. PMID: 28128970.
      Citations: 1033     Fields:    Translation:Humans
    237. Martinez CH, Freeman CM, Nelson JD, Murray S, Wang X, Budoff MJ, Dransfield MT, Hokanson JE, Kazerooni EA, Kinney GL, Regan EA, Wells JM, Martinez FJ, Han MK, Curtis JL, COPDGene Investigators. GDF-15 plasma levels in chronic obstructive pulmonary disease are associated with subclinical coronary artery disease. Respir Res. 2017 02 28; 18(1):42. PMID: 28245821; PMCID: PMC5331711.
      Citations: 9     Fields:    Translation:Humans
    238. Keene JD, Jacobson S, Kechris K, Kinney GL, Foreman MG, Doerschuk CM, Make BJ, Curtis JL, Rennard SI, Barr RG, Bleecker ER, Kanner RE, Kleerup EC, Hansel NN, Woodruff PG, Han MK, Paine R, Martinez FJ, Bowler RP, O'Neal WK, COPDGene and SPIROMICS Investigators ?. Biomarkers Predictive of Exacerbations in the SPIROMICS and COPDGene Cohorts. Am J Respir Crit Care Med. 2017 02 15; 195(4):473-481. PMID: 27579823; PMCID: PMC5378424.
      Citations: 52     Fields:    Translation:HumansCTClinical Trials
    239. Martinez CH, Diaz AA, Meldrum C, Curtis JL, Cooper CB, Pirozzi C, Kanner RE, Paine R, Woodruff PG, Bleecker ER, Hansel NN, Barr RG, Marchetti N, Criner GJ, Kazerooni EA, Hoffman EA, Ross BD, Galban CJ, Cigolle CT, Martinez FJ, Han MK, SPIROMICS Investigators. Age and Small Airway Imaging Abnormalities in Subjects with and without Airflow Obstruction in SPIROMICS. Am J Respir Crit Care Med. 2017 Feb 15; 195(4):464-472. PMID: 27564413; PMCID: PMC5378423.
      Citations: 31     Fields:    Translation:Humans
    240. Arora K, Kelley J, Sui D, Ning J, Martinez F, Lichtiger B, Tholpady A. Cancer type predicts alloimmunization following RhD-incompatible RBC transfusions. Transfusion. 2017 04; 57(4):952-958. PMID: 28191636.
      Citations: 4     Fields:    Translation:HumansCTClinical Trials
    241. Reisner C, Fabbri LM, Kerwin EM, Fogarty C, Spangenthal S, Rabe KF, Ferguson GT, Martinez FJ, Donohue JF, Darken P, St Rose E, Orevillo C, Strom S, Fischer T, Golden M, Dwivedi S. A randomized, seven-day study to assess the efficacy and safety of a glycopyrrolate/formoterol fumarate fixed-dose combination metered dose inhaler using novel Co-Suspension? Delivery Technology in patients with moderate-to-very severe chronic obstructive pulmonary disease. Respir Res. 2017 01 06; 18(1):8. PMID: 28061907; PMCID: PMC5216561.
      Citations: 10     Fields:    Translation:HumansCTClinical Trials
    242. Tholpady A, Kelley J, Martinez F, Lichtiger B. Granulocytes exposed. Transfusion. 2017 01; 57(1):8. PMID: 28097698.
      Citations:    Fields:    Translation:HumansCells
    243. Han MK, Wedzicha JA, Woodruff PG, Martinez FJ, Rodriguez-Roisin R, Vestbo J. Chronic Respiratory Symptoms with Normal Spirometry. A Reliable Clinical Entity? Am J Respir Crit Care Med. 2017 Jan 01; 195(1):17-22. PMID: 27598473.
      Citations: 21     Fields:    Translation:Humans
    244. Ash SY, Harmouche R, Ross JC, Diaz AA, Hunninghake GM, Putman RK, Onieva J, Martinez FJ, Choi AM, Lynch DA, Hatabu H, Rosas IO, Estepar RSJ, Washko GR. The Objective Identification and Quantification of Interstitial Lung Abnormalities in Smokers. Acad Radiol. 2017 08; 24(8):941-946. PMID: 27989445; PMCID: PMC5472510.
      Citations: 18     Fields:    Translation:Humans
    245. Martinez FJ, Rabe KF, Ferguson GT, Fabbri LM, Rennard S, Feldman GJ, Sethi S, Spangenthal S, Gottschlich GM, Arora S, Siler TM, Siddiqui S, Darken P, Fischer T, Maes A, Golden M, Orevillo C, Reisner C, Rodriguez-Roisin R. Efficacy and Safety of Glycopyrrolate/Formoterol Metered Dose Inhaler Formulated Using Co-Suspension Delivery Technology in Patients With COPD. Chest. 2017 Feb; 151(2):340-357. PMID: 27916620.
      Citations: 45     Fields:    Translation:HumansCTClinical Trials
    246. Sethi S, Fogarty C, Hanania NA, Martinez FJ, Rennard S, Fries M, Orevillo C, Darken P, St Rose E, Strom S, Fischer T, Golden M, Dwivedi S, Reisner C. Efficacy of Formoterol Fumarate Delivered by Metered Dose Inhaler Using Co-Suspension? Delivery Technology Versus Foradil? Aerolizer? in Moderate-To-Severe COPD: A Randomized, Dose-Ranging Study. Chronic Obstr Pulm Dis. 2016 Nov 17; 4(1):21-33. PMID: 28848908; PMCID: PMC5560247.
      Citations: 4     
    247. Wise RA, Acevedo RA, Anzueto AR, Hanania NA, Martinez FJ, Ohar JA, Tashkin DP. Guiding Principles for the Use of Nebulized Long-Acting Beta2-Agonists in Patients with COPD: An Expert Panel Consensus. Chronic Obstr Pulm Dis. 2016 Nov 15; 4(1):7-20. PMID: 28848907; PMCID: PMC5560246.
      Citations: 3     
    248. White ES, Xia M, Murray S, Dyal R, Flaherty CM, Flaherty KR, Moore BB, Cheng L, Doyle TJ, Villalba J, Dellaripa PF, Rosas IO, Kurtis JD, Martinez FJ. Plasma Surfactant Protein-D, Matrix Metalloproteinase-7, and Osteopontin Index Distinguishes Idiopathic Pulmonary Fibrosis from Other Idiopathic Interstitial Pneumonias. Am J Respir Crit Care Med. 2016 11 15; 194(10):1242-1251. PMID: 27149370; PMCID: PMC5114439.
      Citations: 53     Fields:    Translation:Humans
    249. Nathan SD, Cottin V, Collard HR, Hoeper MM, Martinez FJ, Wells AU, Behr J. Idiopathic interstitial pneumonia-associated pulmonary hypertension: A target for therapy? Respir Med. 2017 01; 122 Suppl 1:S10-S13. PMID: 27884593.
      Citations: 3     Fields:    Translation:HumansCells
    250. Long-Term Oxygen Treatment Trial Research Group, Albert RK, Au DH, Blackford AL, Casaburi R, Cooper JA, Criner GJ, Diaz P, Fuhlbrigge AL, Gay SE, Kanner RE, MacIntyre N, Martinez FJ, Panos RJ, Piantadosi S, Sciurba F, Shade D, Stibolt T, Stoller JK, Wise R, Yusen RD, Tonascia J, Sternberg AL, Bailey W. A Randomized Trial of Long-Term Oxygen for COPD with Moderate Desaturation. N Engl J Med. 2016 10 27; 375(17):1617-1627. PMID: 27783918; PMCID: PMC5216457.
      Citations: 82     Fields:    Translation:Humans
    251. Martinez FJ, Pratt GA, Van Nostrand EL, Batra R, Huelga SC, Kapeli K, Freese P, Chun SJ, Ling K, Gelboin-Burkhart C, Fijany L, Wang HC, Nussbacher JK, Broski SM, Kim HJ, Lardelli R, Sundararaman B, Donohue JP, Javaherian A, Lykke-Andersen J, Finkbeiner S, Bennett CF, Ares M, Burge CB, Taylor JP, Rigo F, Yeo GW. Protein-RNA Networks Regulated by Normal and ALS-Associated Mutant HNRNPA2B1 in the Nervous System. Neuron. 2016 Nov 23; 92(4):780-795. PMID: 27773581; PMCID: PMC5123850.
      Citations: 66     Fields:    Translation:HumansAnimalsCells
    252. Sieren JP, Newell JD, Barr RG, Bleecker ER, Burnette N, Carretta EE, Couper D, Goldin J, Guo J, Han MK, Hansel NN, Kanner RE, Kazerooni EA, Martinez FJ, Rennard S, Woodruff PG, Hoffman EA, SPIROMICS Research Group. SPIROMICS Protocol for Multicenter Quantitative Computed Tomography to Phenotype the Lungs. Am J Respir Crit Care Med. 2016 10 01; 194(7):794-806. PMID: 27482984; PMCID: PMC5074650.
      Citations: 100     Fields:    Translation:Humans
    253. Tashkin DP, Martinez FJ, Fogarty C, Gotfried M, Denenberg M, Gottschlich G, Donohue JF, Orevillo C, Darken P, St Rose E, Strom S, Fischer T, Golden M, Reisner C, Rodriguez-Roisin R. A multicenter, randomized, double-blind dose-ranging study of glycopyrrolate/formoterol fumarate fixed-dose combination metered dose inhaler compared to the monocomponents and open-label tiotropium dry powder inhaler in patients with moderate-to-severe COPD. Respir Med. 2016 11; 120:16-24. PMID: 27817811.
      Citations: 9     Fields:    Translation:HumansCTClinical Trials
    254. Oldham JM, Noth I, Martinez FJ. Pharmacogenetics and interstitial lung disease. Curr Opin Pulm Med. 2016 09; 22(5):456-65. PMID: 27253772; PMCID: PMC5004343.
      Citations:    Fields:    Translation:Humans
    255. Martinez FJ, Sethi S, Pizzichini E, McIvor A, Anzueto A, Alagappan VK, Siddiqui S, Rekeda L, Miller CJ, Zetterstrand S, Reisner C, Rennard SI, Rabe KF. Effect of Roflumilast and Inhaled Corticosteroid/Long-Acting ?2-Agonist on Chronic Obstructive Pulmonary Disease Exacerbations (RE(2)SPOND). A Randomized Clinical Trial. Am J Respir Crit Care Med. 2016 09 01; 194(5):559-67. PMID: 27585384.
      Citations: 43     Fields:    Translation:HumansCTClinical Trials
    256. Singh D, Halpin D, Wedzicha JA, Martinez FJ, Roche N, Agusti A. Current Controversies in the Pharmacological Treatment of Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2016 09 01; 194(5):541-9. PMID: 27585383.
      Citations: 22     Fields:    Translation:Humans
    257. Rennard SI, Martinez FJ, Sethi S, Pizzichini E, McIvor A, Siddiqui S, Anzueto A, Zhu H, Rabe KF. Effects of roflumilast in COPD patients receiving inhaled corticosteroid/long-acting ?2-agonist fixed-dose combination: RE(2)SPOND rationale and study design. Int J Chron Obstruct Pulmon Dis. 2016; 11:1921-8. PMID: 27574416; PMCID: PMC4994799.
      Citations: 4     Fields:    Translation:HumansCTClinical Trials
    258. Sun W, Kechris K, Jacobson S, Drummond MB, Hawkins GA, Yang J, Chen TH, Quibrera PM, Anderson W, Barr RG, Basta PV, Bleecker ER, Beaty T, Casaburi R, Castaldi P, Cho MH, Comellas A, Crapo JD, Criner G, Demeo D, Christenson SA, Couper DJ, Curtis JL, Doerschuk CM, Freeman CM, Gouskova NA, Han MK, Hanania NA, Hansel NN, Hersh CP, Hoffman EA, Kaner RJ, Kanner RE, Kleerup EC, Lutz S, Martinez FJ, Meyers DA, Peters SP, Regan EA, Rennard SI, Scholand MB, Silverman EK, Woodruff PG, O'Neal WK, Bowler RP, SPIROMICS Research Group, COPDGene Investigators. Common Genetic Polymorphisms Influence Blood Biomarker Measurements in COPD. PLoS Genet. 2016 Aug; 12(8):e1006011. PMID: 27532455; PMCID: PMC4988780.
      Citations: 50     Fields:    Translation:Humans
    259. Salisbury ML, Xia M, Murray S, Bartholmai BJ, Kazerooni EA, Meldrum CA, Martinez FJ, Flaherty KR. Predictors of idiopathic pulmonary fibrosis in absence of radiologic honeycombing: A cross sectional analysis in ILD patients undergoing lung tissue sampling. Respir Med. 2016 09; 118:88-95. PMID: 27578476; PMCID: PMC5008035.
      Citations: 15     Fields:    Translation:Humans
    260. Bhatt SP, Soler X, Wang X, Murray S, Anzueto AR, Beaty TH, Boriek AM, Casaburi R, Criner GJ, Diaz AA, Dransfield MT, Curran-Everett D, Hoffman EA, Hogg JC, Kazerooni EA, Kim V, Kinney GL, Lagstein A, Lynch DA, Make BJ, Martinez FJ, Ramsdell JW, Reddy R, Ross BD, Rossiter HB, Steiner RM, Strand MJ, van Beek EJ, Wan ES, Washko GR, Wells JM, Wendt CH, Wise RA, Silverman EK, Crapo JD, Bowler RP, Han MK, COPDGene Investigators, Galb?n CJ. Association between Functional Small Airway Disease and FEV1 Decline in Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2016 07 15; 194(2):178-84. PMID: 26808615; PMCID: PMC5003216.
      Citations: 128     Fields:    Translation:Humans
    261. Han MK, Martinez CH, Au DH, Bourbeau J, Boyd CM, Branson R, Criner GJ, Kalhan R, Kallstrom TJ, King A, Krishnan JA, Lareau SC, Lee TA, Lindell K, Mannino DM, Martinez FJ, Meldrum C, Press VG, Thomashow B, Tycon L, Sullivan JL, Walsh J, Wilson KC, Wright J, Yawn B, Zueger PM, Bhatt SP, Dransfield MT. Meeting the challenge of COPD care delivery in the USA: a multiprovider perspective. Lancet Respir Med. 2016 06; 4(6):473-526. PMID: 27185520.
      Citations: 34     Fields:    Translation:Humans
    262. Woodruff PG, Barr RG, Bleecker E, Christenson SA, Couper D, Curtis JL, Gouskova NA, Hansel NN, Hoffman EA, Kanner RE, Kleerup E, Lazarus SC, Martinez FJ, Paine R, Rennard S, Tashkin DP, Han MK, SPIROMICS Research Group. Clinical Significance of Symptoms in Smokers with Preserved Pulmonary Function. N Engl J Med. 2016 May 12; 374(19):1811-21. PMID: 27168432; PMCID: PMC4968204.
      Citations: 234     Fields:    Translation:Humans
    263. Martinez FJ, O'Connor GT. Screening, Case-Finding, and Outcomes for Adults With Unrecognized COPD. JAMA. 2016 Apr 05; 315(13):1343-4. PMID: 27046363.
      Citations: 10     Fields:    Translation:Humans
    264. Putcha N, Barr RG, Han MK, Woodruff PG, Bleecker ER, Kanner RE, Martinez FJ, Smith BM, Tashkin DP, Bowler RP, Eisner MD, Rennard SI, Wise RA, Hansel NN, SPIROMICS Investigators. Understanding the impact of second-hand smoke exposure on clinical outcomes in participants with COPD in the SPIROMICS cohort. Thorax. 2016; 71:411-420. PMID: 26962015; PMCID: PMC5235992.
      Citations: 6     Fields:    
    265. Salisbury ML, Xia M, Zhou Y, Murray S, Tayob N, Brown KK, Wells AU, Schmidt SL, Martinez FJ, Flaherty KR. Idiopathic Pulmonary Fibrosis: Gender-Age-Physiology Index Stage for Predicting Future Lung Function Decline. Chest. 2016 Feb; 149(2):491-498. PMID: 26425858; PMCID: PMC4944785.
      Citations: 23     Fields:    
    266. Cata JP, Gutierrez C, Mehran RJ, Rice D, Nates J, Feng L, Rodriguez-Restrepo A, Martinez F, Mena G, Gottumukkala V. Preoperative anemia, blood transfusion, and neutrophil-to-lymphocyte ratio in patients with stage i non-small cell lung cancer. Cancer Cell Microenviron. 2016; 3(1):e1116. PMID: 26949721; PMCID: PMC4774558.
      Citations: 12     
    267. Martinez CH, Diaz AA, Parulekar AD, Rennard SI, Kanner RE, Hansel NN, Couper D, Holm KE, Hoth KF, Curtis JL, Martinez FJ, Hanania NA, Regan EA, Paine R, Cigolle CT, Han MK, COPDGene and SPIROMICS Investigators. Age-Related Differences in Health-Related Quality of Life in COPD: An Analysis of the COPDGene and SPIROMICS Cohorts. Chest. 2016 Apr; 149(4):927-35. PMID: 26836895; PMCID: PMC4944781.
      Citations: 9     Fields:    Translation:Humans
    268. Oldham JM, Ma SF, Martinez FJ, Anstrom KJ, Raghu G, Schwartz DA, Valenzi E, Witt L, Lee C, Vij R, Huang Y, Strek ME, Noth I, IPFnet Investigators. TOLLIP, MUC5B, and the Response to N-Acetylcysteine among Individuals with Idiopathic Pulmonary Fibrosis. Am J Respir Crit Care Med. 2015 Dec 15; 192(12):1475-82. PMID: 26331942; PMCID: PMC4731723.
      Citations: 89     Fields:    Translation:Humans
    269. Dickson RP, Erb-Downward JR, Martinez FJ, Huffnagle GB. The Microbiome and the Respiratory Tract. Annu Rev Physiol. 2016; 78:481-504. PMID: 26527186; PMCID: PMC4751994.
      Citations: 270     Fields:    Translation:HumansAnimals
    270. Raghu G, Martinez FJ, Brown KK, Costabel U, Cottin V, Wells AU, Lancaster L, Gibson KF, Haddad T, Agarwal P, Mack M, Dasgupta B, Nnane IP, Flavin SK, Barnathan ES. CC-chemokine ligand 2 inhibition in idiopathic pulmonary fibrosis: a phase 2 trial of carlumab. Eur Respir J. 2015 Dec; 46(6):1740-50. PMID: 26493793.
      Citations: 39     Fields:    Translation:HumansCTClinical Trials
    271. DeYoung Sullivan K, Vu T, Richardson G, Castillo E, Martinez F. Evaluating the frequency of vital sign monitoring during blood transfusion: an evidence-based practice initiative. Clin J Oncol Nurs. 2015 Oct; 19(5):516-20. PMID: 26414570.
      Citations:    Fields:    Translation:Humans
    272. Boes JL, Bule M, Hoff BA, Chamberlain R, Lynch DA, Stojanovska J, Martinez FJ, Han MK, Kazerooni EA, Ross BD, Galb?n CJ. The Impact of Sources of Variability on Parametric Response Mapping of Lung CT Scans. Tomography. 2015 Sep; 1(1):69-77. PMID: 26568983; PMCID: PMC4643661.
      Citations: 12     Fields:    
    273. Lee SR, Pratt GA, Martinez FJ, Yeo GW, Lykke-Andersen J. Target Discrimination in Nonsense-Mediated mRNA Decay Requires Upf1 ATPase Activity. Mol Cell. 2015 Aug 06; 59(3):413-25. PMID: 26253027; PMCID: PMC4673969.
      Citations: 59     Fields:    Translation:HumansCells
    274. Raghu G, Nathan SD, Behr J, Brown KK, Egan JJ, Kawut SM, Flaherty KR, Martinez FJ, Wells AU, Shao L, Zhou H, Henig N, Szwarcberg J, Gillies H, Montgomery AB, O'Riordan TG. Pulmonary hypertension in idiopathic pulmonary fibrosis with mild-to-moderate restriction. Eur Respir J. 2015 Nov; 46(5):1370-7. PMID: 26250495.
      Citations: 30     Fields:    Translation:HumansCTClinical Trials
    275. Freeman CM, Martinez CH, Todt JC, Martinez FJ, Han MK, Thompson DL, McCloskey L, Curtis JL. Acute exacerbations of chronic obstructive pulmonary disease are associated with decreased CD4+ & CD8+ T cells and increased growth & differentiation factor-15 (GDF-15) in peripheral blood. Respir Res. 2015 Aug 05; 16:94. PMID: 26243260; PMCID: PMC4531816.
      Citations: 28     Fields:    Translation:HumansCellsCTClinical Trials
    276. Celli BR, Decramer M, Wedzicha JA, Wilson KC, Criner GJ, MacNee W, Make BJ, Rennard SI, Stockley RA, Vogelmeier C, Anzueto A, Au DH, Barnes PJ, Burgel PR, Calverley PM, Casanova C, Clini EM, Cooper CB, Coxson HO, Dusser DJ, Fabbri LM, Fahy B, Ferguson GT, Fisher A, Fletcher MJ, Hayot M, Hurst JR, Jones PW, Mahler DA, Mannino DM, Martinez FJ, Miravitlles M, Meek PM, Papi A, Rabe KF, Roche N, Sciurba FC, Sethi S, Siafakas N, Sin DD, Soriano JB, Stoller JK, Tashkin DP, Troosters T, Verleden GM, Verschakelen J, Vestbo J, Walsh JW, Washko GR, Wise RA, Wouters EF, ZuWallack RL, ATS/ERS Task Force for COPD Research, Agust? AA, Maltais F. An official American Thoracic Society/European Respiratory Society statement: research questions in COPD. Eur Respir Rev. 2015 Jun; 24(136):159-72. PMID: 26028628; PMCID: PMC9487818.
      Citations: 22     Fields:    Translation:Humans
    277. Woodruff PG, Agusti A, Singh D, Martinez FJ, Roche N. Current concepts in targeting chronic obstructive pulmonary disease pharmacotherapy: making progress towards personalised management. Lancet. 2015 May 02; 385(9979):1789-1798. PMID: 25943943; PMCID: PMC4869530.
      Citations: 69     Fields:    Translation:HumansCells
    278. Durheim MT, Collard HR, Roberts RS, Brown KK, Flaherty KR, King TE, Palmer SM, Raghu G, Snyder LD, Anstrom KJ, Martinez FJ, IPFnet investigators. Association of hospital admission and forced vital capacity endpoints with survival in patients with idiopathic pulmonary fibrosis: analysis of a pooled cohort from three clinical trials. Lancet Respir Med. 2015 May; 3(5):388-96. PMID: 25890798; PMCID: PMC4760351.
      Citations: 26     Fields:    Translation:Humans
    279. Celli BR, Decramer M, Wedzicha JA, Wilson KC, Criner GJ, MacNee W, Make BJ, Rennard SI, Stockley RA, Vogelmeier C, Anzueto A, Au DH, Barnes PJ, Burgel PR, Calverley PM, Casanova C, Clini EM, Cooper CB, Coxson HO, Dusser DJ, Fabbri LM, Fahy B, Ferguson GT, Fisher A, Fletcher MJ, Hayot M, Hurst JR, Jones PW, Mahler DA, Mannino DM, Martinez FJ, Miravitlles M, Meek PM, Papi A, Rabe KF, Roche N, Sciurba FC, Sethi S, Siafakas N, Sin DD, Soriano JB, Stoller JK, Tashkin DP, Troosters T, Verleden GM, Verschakelen J, Vestbo J, Walsh JW, Washko GR, Wise RA, Wouters EF, ZuWallack RL, ATS/ERS Task Force for COPD Research, Agust? A, Maltais F. An official American Thoracic Society/European Respiratory Society statement: research questions in COPD. Eur Respir J. 2015 Apr; 45(4):879-905. PMID: 25829431.
      Citations: 47     Fields:    Translation:Humans
    280. Celli BR, Decramer M, Wedzicha JA, Wilson KC, Criner GJ, MacNee W, Make BJ, Rennard SI, Stockley RA, Vogelmeier C, Anzueto A, Au DH, Barnes PJ, Burgel PR, Calverley PM, Casanova C, Clini EM, Cooper CB, Coxson HO, Dusser DJ, Fabbri LM, Fahy B, Ferguson GT, Fisher A, Fletcher MJ, Hayot M, Hurst JR, Jones PW, Mahler DA, Mannino DM, Martinez FJ, Miravitlles M, Meek PM, Papi A, Rabe KF, Roche N, Sciurba FC, Sethi S, Siafakas N, Sin DD, Soriano JB, Stoller JK, Tashkin DP, Troosters T, Verleden GM, Verschakelen J, Vestbo J, Walsh JW, Washko GR, Wise RA, Wouters EF, ZuWallack RL, ATS/ERS Task Force for COPD Research, Agust? A, Maltais F. An Official American Thoracic Society/European Respiratory Society Statement: Research questions in chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2015 Apr 01; 191(7):e4-e27. PMID: 25830527.
      Citations: 70     Fields:    Translation:Humans
    281. Martinez FJ, Calverley PM, Goehring UM, Brose M, Fabbri LM, Rabe KF. Effect of roflumilast on exacerbations in patients with severe chronic obstructive pulmonary disease uncontrolled by combination therapy (REACT): a multicentre randomised controlled trial. Lancet. 2015 Mar 07; 385(9971):857-66. PMID: 25684586.
      Citations: 114     Fields:    Translation:HumansCTClinical Trials
    282. Berry CE, Han MK, Thompson B, Limper AH, Martinez FJ, Schwarz MI, Sciurba FC, Criner GJ, Wise RA. Older adults with chronic lung disease report less limitation compared with younger adults with similar lung function impairment. Ann Am Thorac Soc. 2015 Jan; 12(1):21-6. PMID: 25473938; PMCID: PMC4342802.
      Citations: 6     Fields:    Translation:Humans
    283. Han MK, Steenrod AW, Bacci ED, Leidy NK, Mannino DM, Thomashow BM, Barr RG, Make BJ, Bowler RP, Rennard SI, Houfek JF, Yawn BP, Meldrum CA, Walsh JW, Martinez FJ. Identifying Patients with Undiagnosed COPD in Primary Care Settings: Insight from Screening Tools and Epidemiologic Studies. Chronic Obstr Pulm Dis. 2015; 2(2):103-121. PMID: 26236776; PMCID: PMC4521771.
      Citations: 15     
    284. Crim C, Dransfield MT, Bourbeau J, Jones PW, Hanania NA, Mahler DA, Wachtel A, Martinez FJ, Barnhart F, Lettis S, Calverley PM, Vestbo J. Pneumonia risk with inhaled fluticasone furoate and vilanterol compared with vilanterol alone in patients with COPD. Ann Am Thorac Soc. 2015 Jan; 12(1):27-34. PMID: 25490706.
      Citations: 47     Fields:    Translation:Humans
    285. Krahnke JS, Abraham WT, Adamson PB, Bourge RC, Bauman J, Ginn G, Martinez FJ, Criner GJ, Champion Trial Study Group. Heart failure and respiratory hospitalizations are reduced in patients with heart failure and chronic obstructive pulmonary disease with the use of an implantable pulmonary artery pressure monitoring device. J Card Fail. 2015 Mar; 21(3):240-9. PMID: 25541376; PMCID: PMC4405122.
      Citations: 14     Fields:    Translation:Humans
    286. Moore BB, Fry C, Zhou Y, Murray S, Han MK, Martinez FJ, Flaherty KR, The COMET Investigators. Inflammatory leukocyte phenotypes correlate with disease progression in idiopathic pulmonary fibrosis. Front Med. 2014 Dec 22; 1(56). PMID: 25580363; PMCID: PMC4286285.
      Citations: 26     Fields:    
    287. Boes JL, Hoff BA, Bule M, Johnson TD, Rehemtulla A, Chamberlain R, Hoffman EA, Kazerooni EA, Martinez FJ, Han MK, Ross BD, Galb?n CJ. Parametric response mapping monitors temporal changes on lung CT scans in the subpopulations and intermediate outcome measures in COPD Study (SPIROMICS). Acad Radiol. 2015 Feb; 22(2):186-94. PMID: 25442794; PMCID: PMC4289437.
      Citations: 45     Fields:    Translation:Humans
    288. Collard HR, Brown KK, Martinez FJ, Raghu G, Roberts RS, Anstrom KJ. Study design implications of death and hospitalization as end points in idiopathic pulmonary fibrosis. Chest. 2014 Nov; 146(5):1256-1262. PMID: 25144827; PMCID: PMC4219340.
      Citations: 14     Fields:    Translation:Humans
    289. White ES, Brown KK, Collard HR, Conoscenti CS, Cosgrove GP, Flaherty KR, Leff JA, Martinez FJ, Roman J, Rose D, Violette S, Kaminski N. Open-access biorepository for idiopathic pulmonary fibrosis. The way forward. Ann Am Thorac Soc. 2014 Oct; 11(8):1171-5. PMID: 25167209; PMCID: PMC4299004.
      Citations: 8     Fields:    Translation:Humans
    290. Dickson RP, Martinez FJ, Huffnagle GB. The role of the microbiome in exacerbations of chronic lung diseases. Lancet. 2014 Aug 23; 384(9944):691-702. PMID: 25152271; PMCID: PMC4166502.
      Citations: 179     Fields:    Translation:Humans
    291. Dickson RP, Erb-Downward JR, Prescott HC, Martinez FJ, Curtis JL, Lama VN, Huffnagle GB. Cell-associated bacteria in the human lung microbiome. Microbiome. 2014; 2:28. PMID: 25206976; PMCID: PMC4158729.
      Citations: 42     Fields:    
    292. Freeman CM, Stolberg VR, Crudgington S, Martinez FJ, Han MK, Chensue SW, Arenberg DA, Meldrum CA, McCloskey L, Curtis JL. Human CD56+ cytotoxic lung lymphocytes kill autologous lung cells in chronic obstructive pulmonary disease. PLoS One. 2014; 9(7):e103840. PMID: 25078269; PMCID: PMC4117545.
      Citations: 30     Fields:    Translation:HumansCells
    293. Dickson RP, Erb-Downward JR, Prescott HC, Martinez FJ, Curtis JL, Lama VN, Huffnagle GB. Analysis of culture-dependent versus culture-independent techniques for identification of bacteria in clinically obtained bronchoalveolar lavage fluid. J Clin Microbiol. 2014 Oct; 52(10):3605-13. PMID: 25078910; PMCID: PMC4187760.
      Citations: 62     Fields:    Translation:HumansCells
    294. Flaherty KR, Fell C, Aubry MC, Brown K, Colby T, Costabel U, Franks TJ, Gross BH, Hansell DM, Kazerooni E, Kim DS, King TE, Kitachi M, Lynch D, Myers J, Nagai S, Nicholson AG, Poletti V, Raghu G, Selman M, Toews G, Travis W, Wells AU, Vassallo R, Martinez FJ. Smoking-related idiopathic interstitial pneumonia. Eur Respir J. 2014 Sep; 44(3):594-602. PMID: 25063244; PMCID: PMC4366053.
      Citations: 6     Fields:    Translation:HumansPHPublic Health
    295. Dransfield MT, Feldman G, Korenblat P, LaForce CF, Locantore N, Pistolesi M, Watkins ML, Crim C, Martinez FJ. Efficacy and safety of once-daily fluticasone furoate/vilanterol (100/25 mcg) versus twice-daily fluticasone propionate/salmeterol (250/50 mcg) in COPD patients. Respir Med. 2014 Aug; 108(8):1171-9. PMID: 24998880.
      Citations: 9     Fields:    Translation:Humans
    296. Han MK, Tayob N, Murray S, Dransfield MT, Washko G, Scanlon PD, Criner GJ, Casaburi R, Connett J, Lazarus SC, Albert R, Woodruff P, Martinez FJ. Predictors of chronic obstructive pulmonary disease exacerbation reduction in response to daily azithromycin therapy. Am J Respir Crit Care Med. 2014 Jun 15; 189(12):1503-8. PMID: 24779680; PMCID: PMC4226018.
      Citations: 45     Fields:    Translation:Humans
    297. Martinez CH, Okajima Y, Murray S, Washko GR, Martinez FJ, Silverman EK, Lee JH, Regan EA, Crapo JD, Curtis JL, Hatabu H, Han MK, COPDGene Investigators. Impact of self-reported gastroesophageal reflux disease in subjects from COPDGene cohort. Respir Res. 2014 Jun 03; 15:62. PMID: 24894541; PMCID: PMC4049804.
      Citations: 23     Fields:    Translation:HumansCTClinical Trials
    298. Criner GJ, Connett JE, Aaron SD, Albert RK, Bailey WC, Casaburi R, Cooper JA, Curtis JL, Dransfield MT, Han MK, Make B, Marchetti N, Martinez FJ, Niewoehner DE, Scanlon PD, Sciurba FC, Scharf SM, Sin DD, Voelker H, Washko GR, Woodruff PG, Lazarus SC, COPD Clinical Research Network, Canadian Institutes of Health Research. Simvastatin for the prevention of exacerbations in moderate-to-severe COPD. N Engl J Med. 2014 Jun 05; 370(23):2201-10. PMID: 24836125; PMCID: PMC4375247.
      Citations: 89     Fields:    Translation:Humans
    299. Dickson RP, Erb-Downward JR, Freeman CM, Walker N, Scales BS, Beck JM, Martinez FJ, Curtis JL, Lama VN, Huffnagle GB. Changes in the lung microbiome following lung transplantation include the emergence of two distinct Pseudomonas species with distinct clinical associations. PLoS One. 2014; 9(5):e97214. PMID: 24831685; PMCID: PMC4022512.
      Citations: 87     Fields:    Translation:HumansCells
    300. Freeman CM, McCubbrey AL, Crudgington S, Nelson J, Martinez FJ, Han MK, Washko GR, Chensue SW, Arenberg DA, Meldrum CA, McCloskey L, Curtis JL. Basal gene expression by lung CD4+ T cells in chronic obstructive pulmonary disease identifies independent molecular correlates of airflow obstruction and emphysema extent. PLoS One. 2014; 9(5):e96421. PMID: 24805101; PMCID: PMC4013040.
      Citations: 13     Fields:    Translation:HumansCells
    301. Martinez CH, St Jean BL, Plauschinat CA, Rogers B, Beresford J, Martinez FJ, Richardson CR, Han MK. Internet access and use by COPD patients in the National Emphysema/COPD Association Survey. BMC Pulm Med. 2014 Apr 22; 14:66. PMID: 24755090; PMCID: PMC4021217.
      Citations: 14     Fields:    Translation:Humans
    302. Han MK, Zhou Y, Murray S, Tayob N, Noth I, Lama VN, Moore BB, White ES, Flaherty KR, Huffnagle GB, Martinez FJ, COMET Investigators. Lung microbiome and disease progression in idiopathic pulmonary fibrosis: an analysis of the COMET study. Lancet Respir Med. 2014 Jul; 2(7):548-56. PMID: 24767767; PMCID: PMC4142525.
      Citations: 150     Fields:    Translation:HumansCellsCTClinical Trials
    303. Ricci KS, Martinez F, Lichtiger B, Han XY. Septic transfusion reactions during blood transfusion via indwelling central venous catheters. Transfusion. 2014 Oct; 54(10):2412-8. PMID: 24725023.
      Citations:    Fields:    Translation:Humans
    304. Rosas IO, Dellaripa PF, Lederer DJ, Khanna D, Young LR, Martinez FJ. Interstitial lung disease: NHLBI Workshop on the Primary Prevention of Chronic Lung Diseases. Ann Am Thorac Soc. 2014 Apr; 11 Suppl 3:S169-77. PMID: 24754826; PMCID: PMC4112506.
      Citations: 22     Fields:    Translation:HumansPHPublic Health
    305. Schmidt SL, Tayob N, Han MK, Zappala C, Kervitsky D, Murray S, Wells AU, Brown KK, Martinez FJ, Flaherty KR. Predicting pulmonary fibrosis disease course from past trends in pulmonary function. Chest. 2014 Mar 01; 145(3):579-585. PMID: 24231810; PMCID: PMC3941249.
      Citations: 31     Fields:    Translation:Humans
    306. Wedzicha JA, Rabe KF, Martinez FJ, Brose M, Goehring UM, Calverley PMA, Bredenbr?ker D. Response. Chest. 2014 Feb; 145(2):428. PMID: 24493539.
      Citations:    Fields:    Translation:Humans
    307. O'Neal WK, Anderson W, Basta PV, Carretta EE, Doerschuk CM, Barr RG, Bleecker ER, Christenson SA, Curtis JL, Han MK, Hansel NN, Kanner RE, Kleerup EC, Martinez FJ, Miller BE, Peters SP, Rennard SI, Scholand MB, Tal-Singer R, Woodruff PG, Couper DJ, Davis SM, SPIROMICS Investigators. Comparison of serum, EDTA plasma and P100 plasma for luminex-based biomarker multiplex assays in patients with chronic obstructive pulmonary disease in the SPIROMICS study. J Transl Med. 2014 Jan 08; 12:9. PMID: 24397870; PMCID: PMC3928911.
      Citations: 34     Fields:    Translation:Humans
    308. Martinez FJ, Erb-Downward JR, Huffnagle GB. Significance of the microbiome in chronic obstructive pulmonary disease. Ann Am Thorac Soc. 2013 Dec; 10 Suppl:S170-9. PMID: 24313769; PMCID: PMC5478183.
      Citations: 7     Fields:    Translation:Humans
    309. Cata JP, Chukka V, Wang H, Feng L, Gottumukkala V, Martinez F, Vaporciyan AA. Perioperative blood transfusions and survival in patients with non-small cell lung cancer: a retrospective study. BMC Anesthesiol. 2013 Nov 15; 13(1):42. PMID: 24228905; PMCID: PMC3832885.
      Citations: 7     Fields:    
    310. Martinez CH, Kim V, Chen Y, Kazerooni EA, Murray S, Criner GJ, Curtis JL, Regan EA, Wan E, Hersh CP, Silverman EK, Crapo JD, Martinez FJ, Han MK, COPDGene Investigators. The clinical impact of non-obstructive chronic bronchitis in current and former smokers. Respir Med. 2014 Mar; 108(3):491-9. PMID: 24280543; PMCID: PMC3943716.
      Citations: 40     Fields:    Translation:HumansPHPublic Health
    311. Woodruff G, Young JE, Martinez FJ, Buen F, Gore A, Kinaga J, Li Z, Yuan SH, Zhang K, Goldstein LS. The presenilin-1 ?E9 mutation results in reduced ?-secretase activity, but not total loss of PS1 function, in isogenic human stem cells. Cell Rep. 2013 Nov 27; 5(4):974-85. PMID: 24239350; PMCID: PMC3867011.
      Citations: 90     Fields:    Translation:HumansCells
    312. Couper D, LaVange LM, Han M, Barr RG, Bleecker E, Hoffman EA, Kanner R, Kleerup E, Martinez FJ, Woodruff PG, Rennard S, SPIROMICS Research Group. Design of the Subpopulations and Intermediate Outcomes in COPD Study (SPIROMICS). Thorax. 2014 May; 69(5):491-4. PMID: 24029743; PMCID: PMC3954445.
      Citations: 168     Fields:    Translation:Humans
    313. Martinez FJ. Long-acting bronchodilators in COPD: an evolving story. Lancet Respir Med. 2013 Sep; 1(7):499-501. PMID: 24461600.
      Citations:    Fields:    Translation:Humans
    314. Clausen RE, Rasmussen LM, Wang W, Wang Y, Zheng Q, Mickley H, Saaby L, Diederichsen AC, Lambrechtsen J, Martinez FJ, Hogaboam CM, Han M, Larsen MR, Nawrocki A, Vainer B, Krustrup D, Karsdal MA, Leeming DJ, Skj?t-Arkil H, Bj?rling-Poulsen M. Acute Myocardial Infarction and Pulmonary Diseases Result in Two Different Degradation Profiles of Elastin as Quantified by Two Novel ELISAs. PLoS One. 2013; 8(6):e60936. PMID: 23805173; PMCID: PMC3689773.
      Citations: 7     Fields:    Translation:HumansCells
    315. Han MK, Bach DS, Hagan PG, Yow E, Flaherty KR, Toews GB, Anstrom KJ, Martinez FJ, IPFnet Investigators. Sildenafil preserves exercise capacity in patients with idiopathic pulmonary fibrosis and right-sided ventricular dysfunction. Chest. 2013 Jun; 143(6):1699-1708. PMID: 23732584; PMCID: PMC3673665.
      Citations: 53     Fields:    Translation:Humans
    316. Raghu G, Behr J, Brown KK, Egan JJ, Kawut SM, Flaherty KR, Martinez FJ, Nathan SD, Wells AU, Collard HR, Costabel U, Richeldi L, de Andrade J, Khalil N, Morrison LD, Lederer DJ, Shao L, Li X, Pedersen PS, Montgomery AB, Chien JW, O'Riordan TG, ARTEMIS-IPF Investigators*. Treatment of idiopathic pulmonary fibrosis with ambrisentan: a parallel, randomized trial. Ann Intern Med. 2013 May 07; 158(9):641-9. PMID: 23648946.
      Citations: 121     Fields:    Translation:Humans
    317. Wedzicha JA, Rabe KF, Martinez FJ, Brose M, Goehring UM, Calverley PMA, Bredenbr?ker D. Efficacy of roflumilast in the COPD frequent exacerbator phenotype. Chest. 2013 May; 143(5):1302-1311. PMID: 23117188.
      Citations: 34     Fields:    Translation:Humans
    318. Noth I, Zhang Y, Ma SF, Flores C, Barber M, Huang Y, Broderick SM, Wade MS, Hysi P, Scuirba J, Richards TJ, Juan-Guardela BM, Vij R, Han MK, Martinez FJ, Kossen K, Seiwert SD, Christie JD, Nicolae D, Kaminski N, Garcia JGN. Genetic variants associated with idiopathic pulmonary fibrosis susceptibility and mortality: a genome-wide association study. Lancet Respir Med. 2013 Jun; 1(4):309-317. PMID: 24429156; PMCID: PMC3894577.
      Citations: 222     Fields:    Translation:Humans
    319. Dransfield MT, Bourbeau J, Jones PW, Hanania NA, Mahler DA, Wachtel A, Martinez FJ, Barnhart F, Sanford L, Lettis S, Crim C, Calverley PM, Vestbo J. Once-daily inhaled fluticasone furoate and vilanterol versus vilanterol only for prevention of exacerbations of COPD: two replicate double-blind, parallel-group, randomised controlled trials. Lancet Respir Med. 2013 May; 1(3):210-23. PMID: 24429127.
      Citations: 110     Fields:    Translation:Humans
    320. Todt JC, Freeman CM, Brown JP, Sonstein J, Ames TM, McCubbrey AL, Martinez FJ, Chensue SW, Beck JM, Curtis JL. Smoking decreases the response of human lung macrophages to double-stranded RNA by reducing TLR3 expression. Respir Res. 2013 Mar 09; 14:33. PMID: 23497334; PMCID: PMC3599854.
      Citations: 15     Fields:    Translation:HumansCellsCTClinical Trials
    321. Han MK, Lange P, Anzueto A, Martinez FJ, Jones PW. GOLD COPD categories are not fit for purpose in primary care--authors' reply. Lancet Respir Med. 2013 Mar; 1(1):e17-8. PMID: 24321813.
      Citations: 2     Fields:    Translation:Humans
    322. Freeman CM, Martinez FJ, Han MK, Washko GR, McCubbrey AL, Chensue SW, Arenberg DA, Meldrum CA, McCloskey L, Curtis JL. Lung CD8+ T cells in COPD have increased expression of bacterial TLRs. Respir Res. 2013 Feb 01; 14:13. PMID: 23374856; PMCID: PMC3583694.
      Citations: 35     Fields:    Translation:HumansCellsCTClinical Trials
    323. Martinez FJ, Boscia J, Feldman G, Scott-Wilson C, Kilbride S, Fabbri L, Crim C, Calverley PM. Fluticasone furoate/vilanterol (100/25; 200/25 ?g) improves lung function in COPD: a randomised trial. Respir Med. 2013 Apr; 107(4):550-9. PMID: 23332861.
      Citations: 41     Fields:    Translation:Humans
    324. Martinez CH, Raparla S, Plauschinat CA, Giardino ND, Rogers B, Beresford J, Bentkover JD, Schachtner-Appel A, Curtis JL, Martinez FJ, Han MK. Gender differences in symptoms and care delivery for chronic obstructive pulmonary disease. J Womens Health (Larchmt). 2012 Dec; 21(12):1267-74. PMID: 23210491; PMCID: PMC3518541.
      Citations: 20     Fields:    Translation:Humans
    325. Chandra D, Wise RA, Kulkarni HS, Benzo RP, Criner G, Make B, Slivka WA, Ries AL, Reilly JJ, Martinez FJ, Sciurba FC, NETT Research Group. Optimizing the 6-min walk test as a measure of exercise capacity in COPD. Chest. 2012 Dec; 142(6):1545-1552. PMID: 23364913; PMCID: PMC3515028.
      Citations: 13     Fields:    Translation:Humans
    326. Albert RK, Connett J, Curtis JL, Martinez FJ, Han MK, Lazarus SC, Woodruff PG. Mannose-binding lectin deficiency and acute exacerbations of chronic obstructive pulmonary disease. Int J Chron Obstruct Pulmon Dis. 2012; 7:767-77. PMID: 23226013; PMCID: PMC3514010.
      Citations: 5     Fields:    Translation:Humans
    327. Erb-Downward JR, Sadighi Akha AA, Wang J, Shen N, He B, Martinez FJ, Gyetko MR, Curtis JL, Huffnagle GB. Use of direct gradient analysis to uncover biological hypotheses in 16s survey data and beyond. Sci Rep. 2012; 2:774. PMID: 23336065; PMCID: PMC3540687.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    328. Han MK, Boes JL, Chughtai KA, Meyer CR, Johnson TD, Rehemtulla A, Kazerooni EA, Martinez FJ, Ross BD, Galb?n CJ, Galb?n S. Computed tomography-based biomarker provides unique signature for diagnosis of COPD phenotypes and disease progression. Nat Med. 2012 Nov; 18(11):1711-5. PMID: 23042237; PMCID: PMC3493851.
      Citations: 253     Fields:    Translation:Humans
    329. Naik PK, Bozyk PD, Bentley JK, Popova AP, Birch CM, Wilke CA, Fry CD, White ES, Sisson TH, Tayob N, Carnemolla B, Orecchia P, Flaherty KR, Hershenson MB, Murray S, Martinez FJ, Moore BB, COMET Investigators. Periostin promotes fibrosis and predicts progression in patients with idiopathic pulmonary fibrosis. Am J Physiol Lung Cell Mol Physiol. 2012 Dec 15; 303(12):L1046-56. PMID: 23043074; PMCID: PMC3532583.
      Citations: 117     Fields:    Translation:HumansAnimalsCells
    330. Anderson J, Brook RD, Calverley PM, Celli BR, Crim C, Haumann B, Martinez FJ, Yates J, Newby DE, Vestbo J. The Study to Understand Mortality and Morbidity in COPD (SUMMIT) study protocol. Eur Respir J. 2013 May; 41(5):1017-22. PMID: 23018908.
      Citations: 29     Fields:    Translation:Humans
    331. Leeming DJ, Sand JM, Nielsen MJ, Genovese F, Martinez FJ, Hogaboam CM, Han MK, Klickstein LB, Karsdal MA. Serological investigation of the collagen degradation profile of patients with chronic obstructive pulmonary disease or idiopathic pulmonary fibrosis. Biomark Insights. 2012; 7:119-26. PMID: 23012495; PMCID: PMC3448496.
      Citations: 27     
    332. Wells JM, Washko GR, Han MK, Abbas N, Nath H, Mamary AJ, Regan E, Bailey WC, Martinez FJ, Westfall E, Beaty TH, Curran-Everett D, Curtis JL, Hokanson JE, Lynch DA, Make BJ, Crapo JD, Silverman EK, Bowler RP, Dransfield MT, COPDGene Investigators, ECLIPSE Study Investigators. Pulmonary arterial enlargement and acute exacerbations of COPD. N Engl J Med. 2012 Sep 06; 367(10):913-21. PMID: 22938715; PMCID: PMC3690810.
      Citations: 190     Fields:    Translation:Humans
    333. Han MK, Muellerova H, Curran-Everett D, Dransfield MT, Washko GR, Regan EA, Bowler RP, Beaty TH, Hokanson JE, Lynch DA, Jones PW, Anzueto A, Martinez FJ, Crapo JD, Silverman EK, Make BJ. GOLD 2011 disease severity classification in COPDGene: a prospective cohort study. Lancet Respir Med. 2013 Mar; 1(1):43-50. PMID: 24321803; PMCID: PMC4105297.
      Citations: 100     Fields:    Translation:HumansCTClinical Trials
    334. Berry CE, Drummond MB, Han MK, Li D, Fuller C, Limper AH, Martinez FJ, Schwarz MI, Sciurba FC, Wise RA. Relationship between lung function impairment and health-related quality of life in COPD and interstitial lung disease. Chest. 2012 Sep; 142(3):704-711. PMID: 22576634; PMCID: PMC3435139.
      Citations: 16     Fields:    Translation:Humans
    335. Booth AJ, Hadley R, Cornett AM, Dreffs AA, Matthes SA, Tsui JL, Weiss K, Horowitz JC, Fiore VF, Barker TH, Moore BB, Martinez FJ, Niklason LE, White ES. Acellular normal and fibrotic human lung matrices as a culture system for in vitro investigation. Am J Respir Crit Care Med. 2012 Nov 01; 186(9):866-76. PMID: 22936357; PMCID: PMC3530219.
      Citations: 238     Fields:    Translation:HumansCells
    336. Hurd SS, Jones PW, Vogelmeier C, Anzueto A, Barnes PJ, Fabbri LM, Martinez FJ, Nishimura M, Stockley RA, Sin DD, Rodriguez-Roisin R, Vestbo J, Agust? AG. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary. Am J Respir Crit Care Med. 2013 Feb 15; 187(4):347-65. PMID: 22878278.
      Citations: 1885     Fields:    Translation:Humans
    337. Nelson SB, LaVange LM, Nie Y, Walsh JW, Enright PL, Martinez FJ, Mannino DM, Thomashow BM. Questionnaires and pocket spirometers provide an alternative approach for COPD screening in the general population. Chest. 2012 Aug; 142(2):358-366. PMID: 22194590.
      Citations: 20     Fields:    Translation:HumansPHPublic Health
    338. Clausen RE, Nguyen QH, Wang Y, Zheng Q, Martinez FJ, Hogaboam CM, Han M, Klickstein LB, Larsen MR, Nawrocki A, Leeming DJ, Karsdal MA, Skj?t-Arkil H. Measurement of MMP-9 and -12 degraded elastin (ELM) provides unique information on lung tissue degradation. BMC Pulm Med. 2012 Jul 20; 12:34. PMID: 22818364; PMCID: PMC3515477.
      Citations: 24     Fields:    Translation:HumansAnimalsCells
    339. Calverley PM, Martinez FJ, Fabbri LM, Goehring UM, Rabe KF. Does roflumilast decrease exacerbations in severe COPD patients not controlled by inhaled combination therapy? The REACT study protocol. Int J Chron Obstruct Pulmon Dis. 2012; 7:375-82. PMID: 22791991; PMCID: PMC3393336.
      Citations: 18     Fields:    Translation:Humans
    340. Dransfield MT, Harnden S, Burton RL, Albert RK, Bailey WC, Casaburi R, Connett J, Cooper JA, Criner GJ, Curtis JL, Han MK, Make B, Marchetti N, Martinez FJ, McEvoy C, Nahm MH, Niewoehner DE, Porszasz J, Reilly J, Scanlon PD, Scharf SM, Sciurba FC, Washko GR, Woodruff PG, Lazarus SC, NIH COPD Clinical Research Network. Long-term comparative immunogenicity of protein conjugate and free polysaccharide pneumococcal vaccines in chronic obstructive pulmonary disease. Clin Infect Dis. 2012 Sep; 55(5):e35-44. PMID: 22652582; PMCID: PMC3491850.
      Citations: 16     Fields:    Translation:Humans
    341. Martinez CH, Chen YH, Westgate PM, Liu LX, Murray S, Curtis JL, Make BJ, Kazerooni EA, Lynch DA, Marchetti N, Washko GR, Martinez FJ, Han MK, COPDGene Investigators. Relationship between quantitative CT metrics and health status and BODE in chronic obstructive pulmonary disease. Thorax. 2012 May; 67(5):399-406. PMID: 22514236; PMCID: PMC3719874.
      Citations: 60     Fields:    Translation:Humans
    342. Raghu G, Collard HR, Anstrom KJ, Flaherty KR, Fleming TR, King TE, Martinez FJ, Brown KK. Idiopathic pulmonary fibrosis: clinically meaningful primary endpoints in phase 3 clinical trials. Am J Respir Crit Care Med. 2012 May 15; 185(10):1044-8. PMID: 22505745; PMCID: PMC5448580.
      Citations: 65     Fields:    Translation:Humans
    343. Han MK, Huang YJ, Lipuma JJ, Boushey HA, Boucher RC, Cookson WO, Curtis JL, Erb-Downward J, Lynch SV, Sethi S, Toews GB, Young VB, Wolfgang MC, Huffnagle GB, Martinez FJ. Significance of the microbiome in obstructive lung disease. Thorax. 2012 May; 67(5):456-63. PMID: 22318161; PMCID: PMC3578398.
      Citations: 99     Fields:    Translation:Humans
    344. Casaburi R, Porszasz J, Hecht A, Tiep B, Albert RK, Anthonisen NR, Bailey WC, Connett JE, Cooper JA, Criner GJ, Curtis J, Dransfield M, Lazarus SC, Make B, Martinez FJ, McEvoy C, Niewoehner DE, Reilly JJ, Scanlon P, Scharf SM, Sciurba FC, Woodruff P, COPD Clinical Research Network. Influence of lightweight ambulatory oxygen on oxygen use and activity patterns of COPD patients receiving long-term oxygen therapy. COPD. 2012 Feb; 9(1):3-11. PMID: 22292592.
      Citations: 14     Fields:    Translation:Humans
    345. Xu JF, Washko GR, Nakahira K, Hatabu H, Patel AS, Fernandez IE, Nishino M, Okajima Y, Yamashiro T, Ross JC, Diaz AA, Li HP, Qu JM, Himes BE, Come CE, D'Aco K, Martinez FJ, Han MK, Lynch DA, Crapo JD, Morse D, Ryter SW, Silverman EK, Rosas IO, Choi AM, Hunninghake GM, COPDGene Investigators, Est?par RS. Statins and pulmonary fibrosis: the potential role of NLRP3 inflammasome activation. Am J Respir Crit Care Med. 2012 Mar 01; 185(5):547-56. PMID: 22246178; PMCID: PMC3297101.
      Citations: 60     Fields:    Translation:HumansAnimals
    346. Criner GJ, Cordova F, Sternberg AL, Martinez FJ. The National Emphysema Treatment Trial (NETT) Part II: Lessons learned about lung volume reduction surgery. Am J Respir Crit Care Med. 2011 Oct 15; 184(8):881-93. PMID: 21719757; PMCID: PMC3208657.
      Citations: 55     Fields:    Translation:Humans
    347. Criner GJ, Cordova F, Sternberg AL, Martinez FJ. The National Emphysema Treatment Trial (NETT): Part I: Lessons learned about emphysema. Am J Respir Crit Care Med. 2011 Oct 01; 184(7):763-70. PMID: 21757623.
      Citations: 11     Fields:    Translation:Humans
    348. Donohue JF, Martinez FJ. Indacaterol. COPD. 2011 Oct; 8(5):327-8. PMID: 21936681.
      Citations:    Fields:    Translation:Humans
    349. Mannino DM, Martinez FJ. Lifetime risk of COPD: what will the future bring? Lancet. 2011 Sep 10; 378(9795):964-5. PMID: 21907847.
      Citations: 3     Fields:    Translation:Humans
    350. Martinez FJ, Donohue JF, Rennard SI. The future of chronic obstructive pulmonary disease treatment--difficulties of and barriers to drug development. Lancet. 2011 Sep 10; 378(9795):1027-37. PMID: 21907866.
      Citations: 35     Fields:    Translation:HumansAnimals
    351. Albert RK, Connett J, Bailey WC, Casaburi R, Cooper JA, Criner GJ, Curtis JL, Dransfield MT, Han MK, Lazarus SC, Make B, Marchetti N, Martinez FJ, Madinger NE, McEvoy C, Niewoehner DE, Porsasz J, Price CS, Reilly J, Scanlon PD, Sciurba FC, Scharf SM, Washko GR, Woodruff PG, Anthonisen NR, COPD Clinical Research Network. Azithromycin for prevention of exacerbations of COPD. N Engl J Med. 2011 Aug 25; 365(8):689-98. PMID: 21864166; PMCID: PMC3220999.
      Citations: 349     Fields:    Translation:Humans
    352. Come CE, Divo MJ, Sciurba FC, Criner GJ, Marchetti N, Scharf SM, Mosenifar Z, Make BJ, Keller CA, Minai OA, Martinez FJ, Han MK, Reilly JJ, Celli BR, Washko GR, NETT Research Group, San Jos? Est?par R. Lung deflation and oxygen pulse in COPD: results from the NETT randomized trial. Respir Med. 2012 Jan; 106(1):109-19. PMID: 21843930; PMCID: PMC3233645.
      Citations: 16     Fields:    Translation:Humans
    353. Han MK, Martinez FJ. Pharmacotherapeutic approaches to preventing acute exacerbations of chronic obstructive pulmonary disease. Proc Am Thorac Soc. 2011 Aug; 8(4):356-62. PMID: 21816992.
      Citations: 10     Fields:    Translation:HumansPHPublic Health
    354. Han MK, Kazerooni EA, Lynch DA, Liu LX, Murray S, Curtis JL, Criner GJ, Kim V, Bowler RP, Hanania NA, Anzueto AR, Make BJ, Hokanson JE, Crapo JD, Silverman EK, Martinez FJ, Washko GR, COPDGene Investigators. Chronic obstructive pulmonary disease exacerbations in the COPDGene study: associated radiologic phenotypes. Radiology. 2011 Oct; 261(1):274-82. PMID: 21788524; PMCID: PMC3184233.
      Citations: 170     Fields:    Translation:Humans
    355. Martinez F, Falconar AK. The NS1 glycoprotein can generate dramatic antibody-enhanced dengue viral replication in normal out-bred mice resulting in lethal multi-organ disease. PLoS One. 2011; 6(6):e21024. PMID: 21731643; PMCID: PMC3120820.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    356. Dransfield MT, Cockcroft JR, Townsend RR, Coxson HO, Sharma SS, Rubin DB, Emmett AH, Cicale MJ, Crater GD, Martinez FJ. Effect of fluticasone propionate/salmeterol on arterial stiffness in patients with COPD. Respir Med. 2011 Sep; 105(9):1322-30. PMID: 21696934.
      Citations: 14     Fields:    Translation:Humans
    357. Han MK, Curran-Everett D, Dransfield MT, Criner GJ, Zhang L, Murphy JR, Hansel NN, DeMeo DL, Hanania NA, Regan EA, Make BJ, Martinez FJ, Westney GE, Foreman MG, COPDGene Investigators. Racial differences in quality of life in patients with COPD. Chest. 2011 Nov; 140(5):1169-1176. PMID: 21636665; PMCID: PMC3205846.
      Citations: 27     Fields:    Translation:Humans
    358. Erb-Downward JR, Thompson DL, Han MK, Freeman CM, McCloskey L, Schmidt LA, Young VB, Toews GB, Curtis JL, Sundaram B, Martinez FJ, Huffnagle GB. Analysis of the lung microbiome in the "healthy" smoker and in COPD. PLoS One. 2011 Feb 22; 6(2):e16384. PMID: 21364979; PMCID: PMC3043049.
      Citations: 388     Fields:    Translation:HumansCTClinical Trials
    359. Woodruff PG, Albert RK, Bailey WC, Casaburi R, Connett JE, Cooper JA, Criner GJ, Curtis JL, Dransfield MT, Han MK, Harnden SM, Kim V, Marchetti N, Martinez FJ, McEvoy CE, Niewoehner DE, Reilly JJ, Rice K, Scanlon PD, Scharf SM, Sciurba FC, Washko GR, Lazarus SC, Copd Clinical Research Network. Randomized trial of zileuton for treatment of COPD exacerbations requiring hospitalization. COPD. 2011 Feb; 8(1):21-9. PMID: 21299475; PMCID: PMC3775706.
      Citations: 15     Fields:    Translation:Humans
    360. Rennard SI, Calverley PM, Goehring UM, Martinez FJ, Bredenbr?ker D. Reduction of exacerbations by the PDE4 inhibitor roflumilast--the importance of defining different subsets of patients with COPD. Respir Res. 2011 Jan 27; 12:18. PMID: 21272339; PMCID: PMC3040135.
      Citations: 89     Fields:    Translation:Humans
    361. Tarrand J, Lichtiger B, Mart?nez F. Impact on patient outcome following transfusion of bacterially contaminated platelets: the M.D. Anderson Cancer Center experience. Am J Clin Pathol. 2010 Aug; 134(2):207-12. PMID: 20660322.
      Citations: 2     Fields:    Translation:HumansCellsPHPublic Health
    362. Han MK, Agusti A, Calverley PM, Celli BR, Criner G, Curtis JL, Fabbri LM, Goldin JG, Jones PW, Macnee W, Make BJ, Rabe KF, Rennard SI, Sciurba FC, Silverman EK, Washko GR, Wouters EF, Martinez FJ, Vestbo J. Chronic obstructive pulmonary disease phenotypes: the future of COPD. Am J Respir Crit Care Med. 2010 Sep 01; 182(5):598-604. PMID: 20522794; PMCID: PMC6850732.
      Citations: 331     Fields:    Translation:Humans
    363. Freeman CM, Han MK, Martinez FJ, Murray S, Liu LX, Chensue SW, Polak TJ, Sonstein J, Todt JC, Ames TM, Arenberg DA, Meldrum CA, Getty C, McCloskey L, Curtis JL. Cytotoxic potential of lung CD8(+) T cells increases with chronic obstructive pulmonary disease severity and with in vitro stimulation by IL-18 or IL-15. J Immunol. 2010 Jun 01; 184(11):6504-13. PMID: 20427767; PMCID: PMC4098931.
      Citations: 52     Fields:    Translation:HumansCells
    364. Benzo RP, Chang CC, Farrell MH, Kaplan R, Ries A, Martinez FJ, Wise R, Make B, Sciurba F, NETT Research Group. Physical activity, health status and risk of hospitalization in patients with severe chronic obstructive pulmonary disease. Respiration. 2010; 80(1):10-8. PMID: 20234126; PMCID: PMC2889264.
      Citations: 27     Fields:    Translation:Humans
    365. Cho MH, Washko GR, Hoffmann TJ, Criner GJ, Hoffman EA, Martinez FJ, Laird N, Reilly JJ, Silverman EK. Cluster analysis in severe emphysema subjects using phenotype and genotype data: an exploratory investigation. Respir Res. 2010 Mar 16; 11:30. PMID: 20233420; PMCID: PMC2850331.
      Citations: 27     Fields:    Translation:Humans
    366. Hanania NA, Mannino DM, Yawn BP, Mapel DW, Martinez FJ, Donohue JF, Kosinski M, Rendas-Baum R, Mintz M, Samuels S, Jhingran P, Dalal AA. Predicting risk of airflow obstruction in primary care: Validation of the lung function questionnaire (LFQ). Respir Med. 2010 Aug; 104(8):1160-70. PMID: 20226647.
      Citations: 36     Fields:    Translation:Humans
    367. Giardino ND, Curtis JL, Andrei AC, Fan VS, Benditt JO, Lyubkin M, Naunheim K, Criner G, Make B, Wise RA, Murray SK, Fishman AP, Sciurba FC, Liberzon I, Martinez FJ, NETT Research Group. Anxiety is associated with diminished exercise performance and quality of life in severe emphysema: a cross-sectional study. Respir Res. 2010 Mar 09; 11:29. PMID: 20214820; PMCID: PMC2848143.
      Citations: 29     Fields:    Translation:Humans
    368. Yawn BP, Mapel DW, Mannino DM, Martinez FJ, Donohue JF, Hanania NA, Kosinski M, Rendas-Baum R, Mintz M, Samuels S, Dalal AA, Lung Function Questionnaire Working Group. Development of the Lung Function Questionnaire (LFQ) to identify airflow obstruction. Int J Chron Obstruct Pulmon Dis. 2010 Feb 18; 5:1-10. PMID: 20368906; PMCID: PMC2846155.
      Citations: 33     Fields:    Translation:HumansPHPublic Health
    369. Fell CD, Martinez FJ, Liu LX, Murray S, Han MK, Kazerooni EA, Gross BH, Myers J, Travis WD, Colby TV, Toews GB, Flaherty KR. Clinical predictors of a diagnosis of idiopathic pulmonary fibrosis. Am J Respir Crit Care Med. 2010 Apr 15; 181(8):832-7. PMID: 20056903; PMCID: PMC2854332.
      Citations: 72     Fields:    Translation:Humans
    370. Han MK, Swigris J, Liu L, Bartholmai B, Murray S, Giardino N, Thompson B, Frederick M, Li D, Schwarz M, Limper A, Flaherty K, Martinez FJ. Gender influences Health-Related Quality of Life in IPF. Respir Med. 2010 May; 104(5):724-30. PMID: 20036113; PMCID: PMC2862780.
      Citations: 18     Fields:    Translation:Humans
    371. Washko GR, Martinez FJ, Hoffman EA, Loring SH, Diaz AA, Sciurba FC, Silverman EK, Han MK, Decamp M, Reilly JJ, National Emphysema Treatment Trial Research Group, Est?par RS. Physiological and computed tomographic predictors of outcome from lung volume reduction surgery. Am J Respir Crit Care Med. 2010 Mar 01; 181(5):494-500. PMID: 19965810; PMCID: PMC2830400.
      Citations: 19     Fields:    Translation:Humans
    372. Han MK, Bartholmai B, Liu LX, Murray S, Curtis JL, Sciurba FC, Kazerooni EA, Thompson B, Frederick M, Li D, Schwarz M, Limper A, Freeman C, Landreneau RJ, Wise R, Martinez FJ. Clinical significance of radiologic characterizations in COPD. COPD. 2009 Dec; 6(6):459-67. PMID: 19938970.
      Citations: 39     Fields:    Translation:Humans
    373. Matsuoka S, Washko GR, Yamashiro T, Estepar RS, Diaz A, Silverman EK, Hoffman E, Fessler HE, Criner GJ, Marchetti N, Scharf SM, Martinez FJ, Reilly JJ, Hatabu H, National Emphysema Treatment Trial Research Group. Pulmonary hypertension and computed tomography measurement of small pulmonary vessels in severe emphysema. Am J Respir Crit Care Med. 2010 Feb 01; 181(3):218-25. PMID: 19875683; PMCID: PMC2817812.
      Citations: 63     Fields:    Translation:Humans
    374. Freeman CM, Martinez FJ, Han MK, Ames TM, Chensue SW, Todt JC, Arenberg DA, Meldrum CA, Getty C, McCloskey L, Curtis JL. Lung dendritic cell expression of maturation molecules increases with worsening chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2009 Dec 15; 180(12):1179-88. PMID: 19729666; PMCID: PMC2796731.
      Citations: 45     Fields:    Translation:HumansCells
    375. Bailey WC, Sciurba FC, Hanania NA, Donohue JF, Ferguson GT, Zibrak JD, Sharafkhaneh A, Marcus P, Rosa K, Piault EC, Martinez FJ. Development and validation of the Chronic Obstructive Pulmonary Disease Assessment Questionnaire (COPD-AQ). Prim Care Respir J. 2009 Sep; 18(3):198-207. PMID: 19492178; PMCID: PMC6619264.
      Citations: 5     Fields:    Translation:Humans
    376. Calverley PM, Rabe KF, Goehring UM, Fabbri LM, Martinez FJ, M2-124 and M2-125 study groups, Kristiansen S. Roflumilast in symptomatic chronic obstructive pulmonary disease: two randomised clinical trials. Lancet. 2009 Aug 29; 374(9691):685-94. PMID: 19716960.
      Citations: 204     Fields:    Translation:Humans
    377. Fabbri LM, Calverley PM, Bundschuh DS, Brose M, Martinez FJ, Rabe KF, M2-127 and M2-128 study groups, Izquierdo-Alonso JL. Roflumilast in moderate-to-severe chronic obstructive pulmonary disease treated with longacting bronchodilators: two randomised clinical trials. Lancet. 2009 Aug 29; 374(9691):695-703. PMID: 19716961.
      Citations: 146     Fields:    Translation:Humans
    378. Hecker L, Vittal R, Jones T, Jagirdar R, Luckhardt TR, Horowitz JC, Pennathur S, Martinez FJ, Thannickal VJ. NADPH oxidase-4 mediates myofibroblast activation and fibrogenic responses to lung injury. Nat Med. 2009 Sep; 15(9):1077-81. PMID: 19701206; PMCID: PMC2743335.
      Citations: 387     Fields:    Translation:HumansAnimalsCells
    379. Dransfield MT, Nahm MH, Han MK, Harnden S, Criner GJ, Martinez FJ, Scanlon PD, Woodruff PG, Washko GR, Connett JE, Anthonisen NR, Bailey WC, COPD Clinical Research Network. Superior immune response to protein-conjugate versus free pneumococcal polysaccharide vaccine in chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2009 Sep 15; 180(6):499-505. PMID: 19556517; PMCID: PMC2742743.
      Citations: 24     Fields:    Translation:HumansCells
    380. Horowitz JC, Martinez FJ, Thannickal VJ. Mesenchymal cell fate and phenotypes in the pathogenesis of emphysema. COPD. 2009 Jun; 6(3):201-10. PMID: 19811376; PMCID: PMC3524525.
      Citations: 8     Fields:    Translation:HumansCells
    381. Benzo R, Farrell MH, Chang CC, Martinez FJ, Kaplan R, Reilly J, Criner G, Wise R, Make B, Luketich J, Fishman AP, Sciurba FC, NETT Research Group. Integrating health status and survival data: the palliative effect of lung volume reduction surgery. Am J Respir Crit Care Med. 2009 Aug 01; 180(3):239-46. PMID: 19483114; PMCID: PMC2724716.
      Citations: 10     Fields:    Translation:Humans
    382. Kim WJ, Silverman EK, Hoffman E, Criner GJ, Mosenifar Z, Sciurba FC, Make BJ, Carey V, Diaz A, Reilly JJ, Martinez FJ, Washko GR, NETT Research Group, San Jos? Est?par R. CT metrics of airway disease and emphysema in severe COPD. Chest. 2009 Aug; 136(2):396-404. PMID: 19411295; PMCID: PMC2733947.
      Citations: 46     Fields:    Translation:Humans
    383. Chan KM, Martinez FJ, Chang AC. Nonmedical therapy for chronic obstructive pulmonary disease. Proc Am Thorac Soc. 2009 Jan 15; 6(1):137-45. PMID: 19131539.
      Citations: 1     Fields:    Translation:Humans
    384. Drummond MB, Blackford AL, Benditt JO, Make BJ, Sciurba FC, McCormack MC, Martinez FJ, Fessler HE, Fishman AP, Wise RA, NETT Investigators. Continuous oxygen use in nonhypoxemic emphysema patients identifies a high-risk subset of patients: retrospective analysis of the National Emphysema Treatment Trial. Chest. 2008 Sep; 134(3):497-506. PMID: 18641094; PMCID: PMC8477411.
      Citations: 14     Fields:    Translation:Humans
    385. Martinez FJ, Han MK, Andrei AC, Wise R, Murray S, Curtis JL, Sternberg A, Criner G, Gay SE, Reilly J, Make B, Ries AL, Sciurba F, Weinmann G, Mosenifar Z, DeCamp M, Fishman AP, Celli BR, National Emphysema Treatment Trial Research Group. Longitudinal change in the BODE index predicts mortality in severe emphysema. Am J Respir Crit Care Med. 2008 Sep 01; 178(5):491-9. PMID: 18535255; PMCID: PMC2542428.
      Citations: 34     Fields:    Translation:Humans
    386. Martinez FJ, Raczek AE, Seifer FD, Conoscenti CS, Curtice TG, D'Eletto T, Cote C, Hawkins C, Phillips AL, COPD-PS Clinician Working Group. Development and initial validation of a self-scored COPD Population Screener Questionnaire (COPD-PS). COPD. 2008 Apr; 5(2):85-95. PMID: 18415807; PMCID: PMC2430173.
      Citations: 92     Fields:    Translation:Humans
    387. Martinez FJ, Curtis JL, Albert R. Role of macrolide therapy in chronic obstructive pulmonary disease. Int J Chron Obstruct Pulmon Dis. 2008; 3(3):331-50. PMID: 18990961; PMCID: PMC2629987.
      Citations: 40     Fields:    Translation:Humans
    388. Moretti FA, Moore BB, Yan M, Atrasz RG, Wilke CA, Flaherty KR, Martinez FJ, Tsui JL, Sheppard D, Baralle FE, Toews GB, White ES, Muro AF. An essential role for fibronectin extra type III domain A in pulmonary fibrosis. Am J Respir Crit Care Med. 2008 Mar 15; 177(6):638-45. PMID: 18096707; PMCID: PMC2267338.
      Citations: 134     Fields:    Translation:HumansAnimalsCells
    389. Han MK, McLaughlin VV, Criner GJ, Martinez FJ. Pulmonary diseases and the heart. Circulation. 2007 Dec 18; 116(25):2992-3005. PMID: 18086941.
      Citations: 50     Fields:    Translation:Humans
    390. Martinez FJ. Pathogen-directed therapy in acute exacerbations of chronic obstructive pulmonary disease. Proc Am Thorac Soc. 2007 Dec; 4(8):647-58. PMID: 18073397; PMCID: PMC2647652.
      Citations: 5     Fields:    Translation:Humans
    391. Fan VS, Ramsey SD, Giardino ND, Make BJ, Emery CF, Diaz PT, Benditt JO, Mosenifar Z, McKenna R, Curtis JL, Fishman AP, Martinez FJ, National Emphysema Treatment Trial (NETT) Research Group. Sex, depression, and risk of hospitalization and mortality in chronic obstructive pulmonary disease. Arch Intern Med. 2007 Nov 26; 167(21):2345-53. PMID: 18039994.
      Citations: 63     Fields:    Translation:Humans
    392. Huang SK, Wettlaufer SH, Hogaboam CM, Flaherty KR, Martinez FJ, Myers JL, Colby TV, Travis WD, Toews GB, Peters-Golden M. Variable prostaglandin E2 resistance in fibroblasts from patients with usual interstitial pneumonia. Am J Respir Crit Care Med. 2008 Jan 01; 177(1):66-74. PMID: 17916807; PMCID: PMC2176116.
      Citations: 49     Fields:    Translation:HumansCells
    393. Doherty DE, Chapman KR, Martinez FJ, Belfer MH. The value of early diagnosis for effective management of chronic obstructive pulmonary disease. J Fam Pract. 2007 Oct; 56(10 Suppl Value):S1-24. PMID: 17949606.
      Citations: 2     Fields:    Translation:Humans
    394. Anzueto A, Sethi S, Martinez FJ. Exacerbations of chronic obstructive pulmonary disease. Proc Am Thorac Soc. 2007 Oct 01; 4(7):554-64. PMID: 17878469.
      Citations: 48     Fields:    Translation:Humans
    395. Han MK, Postma D, Mannino DM, Giardino ND, Buist S, Curtis JL, Martinez FJ. Gender and chronic obstructive pulmonary disease: why it matters. Am J Respir Crit Care Med. 2007 Dec 15; 176(12):1179-84. PMID: 17673696; PMCID: PMC2720110.
      Citations: 115     Fields:    Translation:Humans
    396. Noth I, Martinez FJ. Recent advances in idiopathic pulmonary fibrosis. Chest. 2007 Aug; 132(2):637-50. PMID: 17699135.
      Citations: 18     Fields:    Translation:Humans
    397. Hogg JC, Chu FS, Tan WC, Sin DD, Patel SA, Pare PD, Martinez FJ, Rogers RM, Make BJ, Criner GJ, Cherniack RM, Sharafkhaneh A, Luketich JD, Coxson HO, Elliott WM, Sciurba FC. Survival after lung volume reduction in chronic obstructive pulmonary disease: insights from small airway pathology. Am J Respir Crit Care Med. 2007 Sep 01; 176(5):454-9. PMID: 17556723; PMCID: PMC1976540.
      Citations: 64     Fields:    Translation:Humans
    398. Han MK, Kim MG, Mardon R, Renner P, Sullivan S, Diette GB, Martinez FJ. Spirometry utilization for COPD: how do we measure up? Chest. 2007 Aug; 132(2):403-9. PMID: 17550936.
      Citations: 72     Fields:    Translation:Humans
    399. Martinez FJ, Curtis JL, Sciurba F, Mumford J, Giardino ND, Weinmann G, Kazerooni E, Murray S, Criner GJ, Sin DD, Hogg J, Ries AL, Han M, Fishman AP, Make B, Hoffman EA, Mohsenifar Z, Wise R, National Emphysema Treatment Trial Research Group. Sex differences in severe pulmonary emphysema. Am J Respir Crit Care Med. 2007 Aug 01; 176(3):243-52. PMID: 17431226; PMCID: PMC1994221.
      Citations: 106     Fields:    Translation:Humans
    400. DeMeo DL, Hersh CP, Hoffman EA, Litonjua AA, Lazarus R, Sparrow D, Benditt JO, Criner G, Make B, Martinez FJ, Scanlon PD, Sciurba FC, Utz JP, Reilly JJ, Silverman EK. Genetic determinants of emphysema distribution in the national emphysema treatment trial. Am J Respir Crit Care Med. 2007 Jul 01; 176(1):42-8. PMID: 17363767; PMCID: PMC2049064.
      Citations: 51     Fields:    Translation:Humans
    401. Lama VN, Murray S, Lonigro RJ, Toews GB, Chang A, Lau C, Flint A, Chan KM, Martinez FJ. Course of FEV(1) after onset of bronchiolitis obliterans syndrome in lung transplant recipients. Am J Respir Crit Care Med. 2007 Jun 01; 175(11):1192-8. PMID: 17347496; PMCID: PMC1899272.
      Citations: 30     Fields:    Translation:Humans
    402. Lama VN, Smith L, Badri L, Flint A, Andrei AC, Murray S, Wang Z, Liao H, Toews GB, Krebsbach PH, Peters-Golden M, Pinsky DJ, Martinez FJ, Thannickal VJ. Evidence for tissue-resident mesenchymal stem cells in human adult lung from studies of transplanted allografts. J Clin Invest. 2007 Apr; 117(4):989-96. PMID: 17347686; PMCID: PMC1810571.
      Citations: 130     Fields:    Translation:HumansCells
    403. Fan VS, Ramsey SD, Make BJ, Martinez FJ. Physiologic variables and functional status independently predict COPD hospitalizations and emergency department visits in patients with severe COPD. COPD. 2007 Mar; 4(1):29-39. PMID: 17364675.
      Citations: 23     Fields:    Translation:Humans
    404. Fell CD, Martinez FJ. The impact of pulmonary arterial hypertension on idiopathic pulmonary fibrosis. Chest. 2007 Mar; 131(3):641-3. PMID: 17356072.
      Citations: 3     Fields:    Translation:Humans
    405. Martinez FJ, Curtis JL. Procalcitonin-guided antibiotic therapy in COPD exacerbations: closer but not quite there. Chest. 2007 Jan; 131(1):1-2. PMID: 17218546.
      Citations: 8     Fields:    Translation:Humans
    406. Flaherty KR, Martinez FJ. Nonspecific interstitial pneumonia. Semin Respir Crit Care Med. 2006 Dec; 27(6):652-8. PMID: 17195141.
      Citations: 5     Fields:    Translation:Humans
    407. Sciurba FC, Martinez FJ, Rogers RM, Make BJ, Criner GJ, Cherniack RM, Patel SA, Chu F, Coxson HO, Sharafkhaneh A, Elliot M, Luketich JD, Hogg JC. Relationship between pathologic characteristics of peripheral airways and outcome after lung volume reduction surgery in severe chronic obstructive pulmonary disease. Proc Am Thorac Soc. 2006 Aug; 3(6):533-4. PMID: 16921138; PMCID: PMC2647645.
      Citations: 4     Fields:    Translation:Humans
    408. Naunheim KS, Wood DE, Mohsenifar Z, Sternberg AL, Criner GJ, DeCamp MM, Deschamps CC, Martinez FJ, Sciurba FC, Tonascia J, Fishman AP, National Emphysema Treatment Trial Research Group. Long-term follow-up of patients receiving lung-volume-reduction surgery versus medical therapy for severe emphysema by the National Emphysema Treatment Trial Research Group. Ann Thorac Surg. 2006 Aug; 82(2):431-43. PMID: 16888872.
      Citations: 67     Fields:    Translation:Humans
    409. Flaherty KR, Andrei AC, Murray S, Fraley C, Colby TV, Travis WD, Lama V, Kazerooni EA, Gross BH, Toews GB, Martinez FJ. Idiopathic pulmonary fibrosis: prognostic value of changes in physiology and six-minute-walk test. Am J Respir Crit Care Med. 2006 Oct 01; 174(7):803-9. PMID: 16825656; PMCID: PMC2648064.
      Citations: 112     Fields:    Translation:Humans
    410. Lama VN, Harada H, Badri LN, Flint A, Hogaboam CM, McKenzie A, Martinez FJ, Toews GB, Moore BB, Pinsky DJ. Obligatory role for interleukin-13 in obstructive lesion development in airway allografts. Am J Pathol. 2006 Jul; 169(1):47-60. PMID: 16816360; PMCID: PMC1698762.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    411. Orens JB, Estenne M, Arcasoy S, Conte JV, Corris P, Egan JJ, Egan T, Keshavjee S, Knoop C, Kotloff R, Martinez FJ, Nathan S, Palmer S, Patterson A, Singer L, Snell G, Studer S, Vachiery JL, Glanville AR, Pulmonary Scientific Council of the International Society for Heart and Lung Transplantation. International guidelines for the selection of lung transplant candidates: 2006 update--a consensus report from the Pulmonary Scientific Council of the International Society for Heart and Lung Transplantation. J Heart Lung Transplant. 2006 Jul; 25(7):745-55. PMID: 16818116.
      Citations: 204     Fields:    Translation:Humans
    412. Martinez FJ, Flaherty K. Pulmonary function testing in idiopathic interstitial pneumonias. Proc Am Thorac Soc. 2006 Jun; 3(4):315-21. PMID: 16738195; PMCID: PMC2658684.
      Citations: 40     Fields:    Translation:Humans
    413. Martinez FJ, Keane MP. Update in diffuse parenchymal lung diseases 2005. Am J Respir Crit Care Med. 2006 May 15; 173(10):1066-71. PMID: 16679445.
      Citations: 5     Fields:    Translation:HumansCells
    414. Martinez FJ, Foster G, Curtis JL, Criner G, Weinmann G, Fishman A, DeCamp MM, Benditt J, Sciurba F, Make B, Mohsenifar Z, Diaz P, Hoffman E, Wise R, NETT Research Group. Predictors of mortality in patients with emphysema and severe airflow obstruction. Am J Respir Crit Care Med. 2006 Jun 15; 173(12):1326-34. PMID: 16543549; PMCID: PMC2662972.
      Citations: 140     Fields:    Translation:Humans
    415. Hersh CP, Demeo DL, Lazarus R, Raby BA, Benditt JO, Criner G, Make B, Martinez FJ, Scanlon PD, Sciurba FC, Utz JP, Reilly JJ, Silverman EK, Celed?n JC. Genetic association analysis of functional impairment in chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2006 May 01; 173(9):977-84. PMID: 16456143; PMCID: PMC2662917.
      Citations: 51     Fields:    Translation:Humans
    416. Martinez FJ, Han MK, Flaherty K, Curtis J. Role of infection and antimicrobial therapy in acute exacerbations of chronic obstructive pulmonary disease. Expert Rev Anti Infect Ther. 2006 Feb; 4(1):101-24. PMID: 16441213.
      Citations: 15     Fields:    Translation:Humans
    417. Martinez FJ. Acute exacerbation of chronic bronchitis: expanding short-course therapy. Int J Antimicrob Agents. 2005 Dec; 26 Suppl 3:S156-63. PMID: 16543077.
      Citations: 1     Fields:    Translation:Humans
    418. Barr RG, Celli BR, Martinez FJ, Ries AL, Rennard SI, Reilly JJ, Sciurba FC, Thomashow BM, Wise RA. Physician and patient perceptions in COPD: the COPD Resource Network Needs Assessment Survey. Am J Med. 2005 Dec; 118(12):1415. PMID: 16378794.
      Citations: 54     Fields:    Translation:Humans
    419. White ES, Atrasz RG, Hu B, Phan SH, Stambolic V, Mak TW, Hogaboam CM, Flaherty KR, Martinez FJ, Kontos CD, Toews GB. Negative regulation of myofibroblast differentiation by PTEN (Phosphatase and Tensin Homolog Deleted on chromosome 10). Am J Respir Crit Care Med. 2006 Jan 01; 173(1):112-21. PMID: 16179636; PMCID: PMC1434700.
      Citations: 103     Fields:    Translation:HumansAnimalsCells
    420. Martinez FJ, Anzueto A. Appropriate outpatient treatment of acute bacterial exacerbations of chronic bronchitis. Am J Med. 2005 Jul; 118 Suppl 7A:39S-44S. PMID: 15993676.
      Citations: 6     Fields:    Translation:Humans
    421. Lama VN, Murray S, Mumford JA, Flaherty KR, Chang A, Toews GB, Peters-Golden M, Martinez FJ. Prognostic value of bronchiolitis obliterans syndrome stage 0-p in single-lung transplant recipients. Am J Respir Crit Care Med. 2005 Aug 01; 172(3):379-83. PMID: 15894603; PMCID: PMC2718475.
      Citations: 19     Fields:    Translation:Humans
    422. Narvios A, Reddy V, Martinez F, Lichtiger B. Slow infusion of platelets: a possible alternative in the management of refractory thrombocytopenic patients. Am J Hematol. 2005 May; 79(1):80. PMID: 15849771.
      Citations: 2     Fields:    Translation:Humans
    423. Martinez FJ, Chang A. Surgical therapy for chronic obstructive pulmonary disease. Semin Respir Crit Care Med. 2005 Apr; 26(2):167-91. PMID: 16088435.
      Citations: 11     Fields:    Translation:Humans
    424. Nemery B, Yew WW, Albert R, Brun-Buisson C, Macnee W, Martinez FJ, Angus DC, Abraham E. Tuberculosis, nontuberculous lung infection, pleural disorders, pulmonary function, respiratory muscles, occupational lung disease, pulmonary infections, and social issues in AJRCCM in 2004. Am J Respir Crit Care Med. 2005 Mar 15; 171(6):554-62. PMID: 15753485.
      Citations: 1     Fields:    Translation:Humans
    425. Martinez FJ, Standiford C, Gay SE. Is it asthma or COPD? The answer determines proper therapy for chronic airflow obstruction. Postgrad Med. 2005 Mar; 117(3):19-26. PMID: 15782670.
      Citations: 4     Fields:    Translation:Humans
    426. Waghray M, Cui Z, Horowitz JC, Subramanian IM, Martinez FJ, Toews GB, Thannickal VJ. Hydrogen peroxide is a diffusible paracrine signal for the induction of epithelial cell death by activated myofibroblasts. FASEB J. 2005 May; 19(7):854-6. PMID: 15857893.
      Citations: 110     Fields:    Translation:HumansCells
    427. Vittal R, Horowitz JC, Moore BB, Zhang H, Martinez FJ, Toews GB, Standiford TJ, Thannickal VJ. Modulation of prosurvival signaling in fibroblasts by a protein kinase inhibitor protects against fibrotic tissue injury. Am J Pathol. 2005 Feb; 166(2):367-75. PMID: 15681821; PMCID: PMC1602319.
      Citations: 74     Fields:    Translation:AnimalsCells
    428. Flaherty KR, Martinez FJ. Cigarette smoking in interstitial lung disease: concepts for the internist. Med Clin North Am. 2004 Nov; 88(6):1643-53, xiii. PMID: 15464118.
      Citations: 3     Fields:    Translation:Humans
    429. Lama VN, Martinez FJ. Resting and exercise physiology in interstitial lung diseases. Clin Chest Med. 2004 Sep; 25(3):435-53, v. PMID: 15331185.
      Citations: 11     Fields:    Translation:Humans
    430. Thannickal VJ, Flaherty KR, Martinez FJ, Lynch JP. Idiopathic pulmonary fibrosis: emerging concepts on pharmacotherapy. Expert Opin Pharmacother. 2004 Aug; 5(8):1671-86. PMID: 15264982.
      Citations: 15     Fields:    Translation:HumansAnimals
    431. Flaherty KR, King TE, Raghu G, Lynch JP, Colby TV, Travis WD, Gross BH, Kazerooni EA, Toews GB, Long Q, Murray S, Lama VN, Gay SE, Martinez FJ. Idiopathic interstitial pneumonia: what is the effect of a multidisciplinary approach to diagnosis? Am J Respir Crit Care Med. 2004 Oct 15; 170(8):904-10. PMID: 15256390.
      Citations: 165     Fields:    Translation:Humans
    432. Martinez FJ. Monotherapy versus dual therapy for community-acquired pneumonia in hospitalized patients. Clin Infect Dis. 2004 May 15; 38 Suppl 4:S328-40. PMID: 15127366.
      Citations: 6     Fields:    Translation:Humans
    433. Martinez FJ. Acute bronchitis: state of the art diagnosis and therapy. Compr Ther. 2004; 30(1):55-69. PMID: 15162593; PMCID: PMC7091331.
      Citations: 3     Fields:    Translation:Humans
    434. Thannickal VJ, Toews GB, White ES, Lynch JP, Martinez FJ. Mechanisms of pulmonary fibrosis. Annu Rev Med. 2004; 55:395-417. PMID: 14746528.
      Citations: 315     Fields:    Translation:Humans
    435. Martinez FJ, Simon RH. Clinical implications of macrolide therapy in chronic sinopulmonary diseases. Curr Pharm Des. 2004; 10(25):3095-110. PMID: 15544500.
      Citations: 3     Fields:    Translation:Humans
    436. Martinez FJ, Flaherty KR, Iannettoni MD. Patient selection for lung volume reduction surgery. Chest Surg Clin N Am. 2003 Nov; 13(4):669-85. PMID: 14682601.
      Citations: 1     Fields:    Translation:Humans
    437. Flaherty KR, Mumford JA, Murray S, Kazerooni EA, Gross BH, Colby TV, Travis WD, Flint A, Toews GB, Lynch JP, Martinez FJ. Prognostic implications of physiologic and radiographic changes in idiopathic interstitial pneumonia. Am J Respir Crit Care Med. 2003 Sep 01; 168(5):543-8. PMID: 12773329.
      Citations: 142     Fields:    Translation:Humans
    438. Kim KK, Flaherty KR, Long Q, Hattori N, Sisson TH, Colby TV, Travis WD, Martinez FJ, Murray S, Simon RH. A plasminogen activator inhibitor-1 promoter polymorphism and idiopathic interstitial pneumonia. Mol Med. 2003 Jan-Feb; 9(1-2):52-6. PMID: 12765340; PMCID: PMC1430380.
      Citations: 7     Fields:    Translation:HumansCells
    439. Lynch III JP, Martinez FJ. Clinical relevance of macrolide-resistant Streptococcus pneumoniae for community-acquired pneumonia. Clin Infect Dis. 2002 Mar 01; 34 Suppl 1:S27-46. PMID: 11810608.
      Citations: 23     Fields:    Translation:HumansCells
    440. Weigle KA, Santrich C, Martinez F, Valderrama L, Saravia NG. Epidemiology of cutaneous leishmaniasis in Colombia: a longitudinal study of the natural history, prevalence, and incidence of infection and clinical manifestations. J Infect Dis. 1993 Sep; 168(3):699-708. PMID: 8354912.
      Citations: 25     Fields:    Translation:HumansAnimals
    441. Weigle KA, Santrich C, Martinez F, Valderrama L, Saravia NG. Epidemiology of cutaneous leishmaniasis in Colombia: environmental and behavioral risk factors for infection, clinical manifestations, and pathogenicity. J Infect Dis. 1993 Sep; 168(3):709-14. PMID: 8354913.
      Citations: 25     Fields:    Translation:HumansAnimalsPHPublic Health
    442. Weigle KA, Escobar M, Arias AL, Martinez F, Rojas C. A clinical prediction rule for American cutaneous leishmaniasis in Colombia. Int J Epidemiol. 1993 Jun; 22(3):548-58. PMID: 8359974.
      Citations: 6     Fields:    Translation:Humans
    443. Evaluating the frequency of vital sign monitoring during blood transfusion. Clinical Journal of Oncology Nursing. 19:516-520.
    444. Perioperative blood transfusions and survival in patients with non-small cell lung cancer. BMC Anesthesiology. 13.
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