SONALGUPTASONAL GUPTA9905GUPTA, SONALAssistant Professorprns:coAuthorOfcoauthor ofFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressvivo:address1address line 1vivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provincevivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentDivisionvivo:hasResearchArearesearch areasvivo:hrJobTitleHR job titleInformation Resourcevivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:personInPositionpositionsPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPerson6565 MD Anderson BlvdHouston77030TXAuthorship 1763594Authorship 178696117068139Martinez O, Gangi E, Mordi D, Gupta S, Dorevitch S, Lefranc MP, Prabhakar BSEndocrinologyDiversity in the complementarity-determining region 3 (CDR3) of antibodies from mice with evolving anti-thyroid-stimulating hormone receptor antibody responses. Endocrinology. 2007 Feb; 148(2):752-61.Endocrinology2006-10-26T00:00:002006Diversity in the complementarity-determining region 3 (CDR3) of antibodies from mice with evolving anti-thyroid-stimulating hormone receptor antibody responses.18373240Gupta S, Shang W, Sun ZArchivum immunologiae et therapiae experimentalisMechanisms regulating the development and function of natural regulatory T cells. Arch Immunol Ther Exp (Warsz). 2008 Mar-Apr; 56(2):85-102.Arch Immunol Ther Exp (Warsz)2008-03-31T00:00:002008Mechanisms regulating the development and function of natural regulatory T cells.Clinical Cancer PreventionExperimental Radiation OncologyGastroenterology Hepatology & NutritionGynecological Oncology & Reproductive MedicineRadiation OncologySurgical OncologyMD AndersonJASON BFLEMINGJASON B FLEMING8742FLEMING, JASON BProfessorWAI CHINFOOWAI CHIN FOO9675FOO, WAI CHINAssistant ProfessorANIRBANMAITRAANIRBAN MAITRA9915MAITRA, ANIRBANProfessorKEPINGXIEKEPING XIE8634XIE, KEPINGProfessorMATTHEW HAROLDKATZMATTHEW HAROLD KATZ9338KATZ, MATTHEW HAROLDAssociate Professor0.7879460.00518187208research areas2.144580.03569328coauthor of34.60894.0050460similar to1128selected publicationsCULLENTANIGUCHICULLEN TANIGUCHI9939TANIGUCHI, CULLENAssistant ProfessorANIL KSOODANIL K SOOD9048SOOD, ANIL KProfessorFLORENCIAMCALLISTERFLORENCIA MCALLISTER9947MCALLISTER, FLORENCIAAssistant ProfessorAuthorship 2230622Authorship 2231162Authorship 231939116709830Manicassamy S, Gupta S, Huang Z, Sun ZJournal of immunology (Baltimore, Md. : 1950)Protein kinase C-theta-mediated signals enhance CD4+ T cell survival by up-regulating Bcl-xL. J Immunol. 2006 Jun 01; 176(11):6709-16.J Immunol2006-06-01T00:00:002006Protein kinase C-theta-mediated signals enhance CD4+ T cell survival by up-regulating Bcl-xL.16978534Manicassamy S, Gupta S, Sun ZCellular & molecular immunologySelective function of PKC-theta in T cells. Cell Mol Immunol. 2006 Aug; 3(4):263-70.Cell Mol Immunol2006-08-01T00:00:002006Selective function of PKC-theta in T cells.22010213Gupta S, Pramanik D, Mukherjee R, Campbell NR, Elumalai S, de Wilde RF, Hong SM, Goggins MG, De Jesus-Acosta A, Laheru D, Maitra AClinical cancer research : an official journal of the American Association for Cancer ResearchMolecular determinants of retinoic acid sensitivity in pancreatic cancer. Clin Cancer Res. 2012 Jan 01; 18(1):280-9.Clin Cancer Res2011-10-18T00:00:002011Molecular determinants of retinoic acid sensitivity in pancreatic cancer.Authorship 2676352Authorship 2687841Authorship 271092418097009Manicassamy S, Gupta S, Huang Z, Molkentin JD, Shang W, Sun ZJournal of immunology (Baltimore, Md. : 1950)Requirement of calcineurin a beta for the survival of naive T cells. J Immunol. 2008 Jan 01; 180(1):106-12.J Immunol2008-01-01T00:00:002008Requirement of calcineurin a beta for the survival of naive T cells.18842300Gupta S, Manicassamy S, Vasu C, Kumar A, Shang W, Sun ZMolecular immunologyDifferential requirement of PKC-theta in the development and function of natural regulatory T cells. Mol Immunol. 2008 Dec; 46(2):213-24.Mol Immunol2008-10-08T00:00:002008Differential requirement of PKC-theta in the development and function of natural regulatory T cells.22791660Pramanik D, Campbell NR, Das S, Gupta S, Chenna V, Bisht S, Sysa-Shah P, Bedja D, Karikari C, Steenbergen C, Gabrielson KL, Maitra A, Maitra AOncotargetA composite polymer nanoparticle overcomes multidrug resistance and ameliorates doxorubicin-associated cardiomyopathy. Oncotarget. 2012 Jun; 3(6):640-50.Oncotarget2012-06-01T00:00:002012A composite polymer nanoparticle overcomes multidrug resistance and ameliorates doxorubicin-associated cardiomyopathy.Authorship 275270123992416Gupta S, Chawla KExpert review of proteomicsOncometabolomics in cancer research. Expert Rev Proteomics. 2013 Aug; 10(4):325-36.Expert Rev Proteomics2013-08-01T00:00:002013Oncometabolomics in cancer research.26675084Wu PH, Phillip JM, Khatau SB, Chen WC, Stirman J, Rosseel S, Tschudi K, Van Patten J, Wong M, Gupta S, Baras AS, Leek JT, Maitra A, Wirtz DScientific reportsEvolution of cellular morpho-phenotypes in cancer metastasis. Sci Rep. 2015 Dec 17; 5:18437.Sci Rep2015-12-17T00:00:002015Evolution of cellular morpho-phenotypes in cancer metastasis.26920219Zhao H, Yang L, Baddour J, Achreja A, Bernard V, Moss T, Marini JC, Tudawe T, Seviour EG, San Lucas FA, Alvarez H, Gupta S, Maiti SN, Cooper L, Peehl D, Ram PT, Maitra A, Nagrath DeLifeTumor microenvironment derived exosomes pleiotropically modulate cancer cell metabolism. Elife. 2016 Feb 27; 5:e10250.Elife2016-02-27T00:00:002016Tumor microenvironment derived exosomes pleiotropically modulate cancer cell metabolism.74Professor10Assistant Professor54Instructor14Associate ProfessorPANKAJ KUMARSINGHPANKAJ KUMAR SINGH11862SINGH, PANKAJ KUMARInstructor27320920Carugo A, Genovese G, Seth S, Nezi L, Rose JL, Bossi D, Cicalese A, Shah PK, Viale A, Pettazzoni PF, Akdemir KC, Bristow CA, Robinson FS, Tepper J, Sanchez N, Gupta S, Estecio MR, Giuliani V, Dellino GI, Riva L, Yao W, Di Francesco ME, Green T, D'Alesio C, Corti D, Kang Y, Jones P, Wang H, Fleming JB, Maitra A, Pelicci PG, Chin L, DePinho RA, Lanfrancone L, Heffernan TP, Draetta GFCell reportsIn?Vivo Functional Platform Targeting Patient-Derived Xenografts Identifies WDR5-Myc Association as a Critical Determinant of Pancreatic Cancer. Cell Rep. 2016 06 28; 16(1):133-147.Cell Rep2016-06-16T00:00:002016In?Vivo Functional Platform Targeting Patient-Derived Xenografts Identifies WDR5-Myc Association as a Critical Determinant of Pancreatic Cancer.Authorship 853253Authorship 854537Authorship 857457Scientific ReportsEvolution of cellular morpho-phenotypes in cancer metastasis. Scientific Reports. 5.Evolution of cellular morpho-phenotypes in cancer metastasisCell ReportsIn Vivo Functional Platform Targeting Patient-Derived Xenografts Identifies WDR5-Myc Association as a Critical Determinant of Pancreatic Cancer. Cell Reports. 16:133-147.In Vivo Functional Platform Targeting Patient-Derived Xenografts Identifies WDR5-Myc Association as a Critical Determinant of Pancreatic CancereLifeTumor microenvironment derived exosomes pleiotropically modulate cancer cell metabolism. eLife. 5.Tumor microenvironment derived exosomes pleiotropically modulate cancer cell metabolismAuthorship 88764910Authorship 88941716Authorship 88961312D011493Chemicals & Drugs2193970.842205Protein Kinase CD053263Physiology3576760.710745Gene Regulatory NetworksD044584Disorders781370.887929Carcinoma, DuctalD010190Disorders69850490.284554Pancreatic NeoplasmsD050378Anatomy3036690.711589T-Lymphocytes, RegulatoryAuthorship 9072793Authorship 9105501Authorship 9164384Authorship 9228008Authorship 9283811126919422Gupta S, Maitra ACellEMT: Matter of Life or Death? Cell. 2016 Feb 25; 164(5):840-2.Cell2016-02-25T00:00:002016EMT: Matter of Life or Death?27496212Mandalapu D, Saini KS, Gupta S, Sharma V, Yaseen Malik M, Chaturvedi S, Bala V, Thakur S, Maikhuri JP, Wahajuddin M, Konwar R, Gupta G, Sharma VLBioorganic & medicinal chemistry lettersSynthesis and biological evaluation of some novel triazole hybrids of curcumin mimics and their selective anticancer activity against breast and prostate cancer cell lines. Bioorg Med Chem Lett. 2016 09 01; 26(17):4223-32.Bioorg Med Chem Lett2016-07-25T00:00:002016Synthesis and biological evaluation of some novel triazole hybrids of curcumin mimics and their selective anticancer activity against breast and prostate cancer cell lines.28986391Bhattacharyya S, Pradhan K, Campbell N, Mazdo J, Vasantkumar A, Maqbool S, Bhagat TD, Gupta S, Suzuki M, Yu Y, Greally JM, Steidl U, Bradner J, Dawlaty M, Godley L, Maitra A, Verma AGenome researchAltered hydroxymethylation is seen at regulatory regions in pancreatic cancer and regulates oncogenic pathways. Genome Res. 2017 11; 27(11):1830-1842.Genome Res2017-10-06T00:00:002017Altered hydroxymethylation is seen at regulatory regions in pancreatic cancer and regulates oncogenic pathways.29604293Zhang Y, Zoltan M, Riquelme E, Xu H, Sahin I, Castro-Pando S, Montiel MF, Chang K, Jiang Z, Ling J, Gupta S, Horne W, Pruski M, Wang H, Sun SC, Lozano G, Chiao P, Maitra A, Leach SD, Kolls JK, Vilar E, Wang TC, Bailey JM, McAllister FGastroenterologyImmune Cell Production of Interleukin 17 Induces Stem Cell Features of Pancreatic Intraepithelial Neoplasia Cells. Gastroenterology. 2018 07; 155(1):210-223.e3.Gastroenterology2018-03-29T00:00:002018Immune Cell Production of Interleukin 17 Induces Stem Cell Features of Pancreatic Intraepithelial Neoplasia Cells.30142336Ideno N, Yamaguchi H, Ghosh B, Gupta S, Okumura T, Steffen DJ, Fisher CG, Wood LD, Singhi AD, Nakamura M, Gutkind JS, Maitra AGastroenterologyGNASR201C Induces Pancreatic Cystic Neoplasms in Mice That Express Activated KRAS by Inhibiting YAP1 Signaling. Gastroenterology. 2018 11; 155(5):1593-1607.e12.Gastroenterology2018-08-22T00:00:002018GNASR201C Induces Pancreatic Cystic Neoplasms in Mice That Express Activated KRAS by Inhibiting YAP1 Signaling.PathologyAuthorship 944247830728464Ideno N, Yamaguchi H, Okumura T, Huang J, Brun MJ, Ho ML, Suh J, Gupta S, Maitra A, Ghosh BLaboratory investigation; a journal of technical methods and pathologyA pipeline for rapidly generating genetically engineered mouse models of pancreatic cancer using in vivo CRISPR-Cas9-mediated somatic recombination. Lab Invest. 2019 Jul; 99(8):1233-1244.Lab Invest2019-02-06T00:00:002019A pipeline for rapidly generating genetically engineered mouse models of pancreatic cancer using in vivo CRISPR-Cas9-mediated somatic recombination.Authorship 9463961031043430Fujimoto TN, Colbert LE, Huang Y, Molkentine JM, Deorukhkar A, Baseler L, Yu M, Lin D, Gupta S, Cabeceiras PK, Kingsley CV, Tailor RC, Sawakuchi GO, Koay EJ, Piwnica-Worms H, Maitra A, Taniguchi CMCancer researchSelective EGLN Inhibition Enables Ablative Radiotherapy and Improves Survival in Unresectable Pancreatic Cancer. Cancer Res. 2019 05 01; 79(9):2327-2338.Cancer Res2019-05-01T00:00:002019Selective EGLN Inhibition Enables Ablative Radiotherapy and Improves Survival in Unresectable Pancreatic Cancer.31335325Yu M, Nguyen ND, Huang Y, Lin D, Fujimoto TN, Molkentine JM, Deorukhkar A, Kang Y, San Lucas FA, Fernandes CJ, Koay EJ, Gupta S, Ying H, Koong AC, Herman JM, Fleming JB, Maitra A, Taniguchi CMJCI insightMitochondrial fusion exploits a therapeutic vulnerability of pancreatic cancer. JCI Insight. 2019 07 23; 5.JCI Insight2019-07-23T00:00:002019Mitochondrial fusion exploits a therapeutic vulnerability of pancreatic cancer.Authorship 95399912Authorship 9560682331557131Tu B, Yao J, Ferri-Borgogno S, Zhao J, Chen S, Wang Q, Yan L, Zhou X, Zhu C, Bang S, Chang Q, Bristow CA, Kang Y, Zheng H, Wang H, Fleming JB, Kim M, Heffernan TP, Draetta GF, Pan D, Maitra A, Yao W, Gupta S, Ying HJCI insightYAP1 oncogene is a context-specific driver for pancreatic ductal adenocarcinoma. JCI Insight. 2019 11 01; 4(21).JCI Insight2019-11-01T00:00:002019YAP1 oncogene is a context-specific driver for pancreatic ductal adenocarcinoma.Authorship 9580852231663852Bhagat TD, Von Ahrens D, Dawlaty M, Zou Y, Baddour J, Achreja A, Zhao H, Yang L, Patel B, Kwak C, Choudhary GS, Gordon-Mitchell S, Aluri S, Bhattacharyya S, Sahu S, Bhagat P, Yu Y, Bartenstein M, Giricz O, Suzuki M, Sohal D, Gupta S, Guerrero PA, Batra S, Goggins M, Steidl U, Greally J, Agarwal B, Pradhan K, Banerjee D, Nagrath D, Maitra A, Verma AeLifeLactate-mediated epigenetic reprogramming regulates formation of human pancreatic cancer-associated fibroblasts. Elife. 2019 11 01; 8.Elife2019-11-01T00:00:002019Lactate-mediated epigenetic reprogramming regulates formation of human pancreatic cancer-associated fibroblasts.Authorship 9983761532860704Zhang Y, Chandra V, Riquelme Sanchez E, Dutta P, Quesada PR, Rakoski A, Zoltan M, Arora N, Baydogan S, Horne W, Burks J, Xu H, Hussain P, Wang H, Gupta S, Maitra A, Bailey JM, Moghaddam SJ, Banerjee S, Sahin I, Bhattacharya P, McAllister FThe Journal of experimental medicineInterleukin-17-induced neutrophil extracellular traps mediate resistance to checkpoint blockade in pancreatic cancer. J Exp Med. 2020 12 07; 217(12).J Exp Med2020-12-07T00:00:002020Interleukin-17-induced neutrophil extracellular traps mediate resistance to checkpoint blockade in pancreatic cancer.Authorship 9999921432967217Ferri-Borgogno S, Barui S, McGee AM, Griffiths T, Singh PK, Piett CG, Ghosh B, Bhattacharyya S, Singhi A, Pradhan K, Verma A, Nagel Z, Maitra A, Gupta SCancersParadoxical Role of AT-rich Interactive Domain 1A in Restraining Pancreatic Carcinogenesis. Cancers (Basel). 2020 Sep 21; 12(9).Cancers (Basel)2020-09-21T00:00:002020Paradoxical Role of AT-rich Interactive Domain 1A in Restraining Pancreatic Carcinogenesis.Authorship 10333951034830866Marcus R, Ferri-Borgogno S, Hosein A, Foo WC, Ghosh B, Zhao J, Rajapakshe K, Brugarolas J, Maitra A, Gupta SCancersOncogenic KRAS Requires Complete Loss of BAP1 Function for Development of Murine Intrahepatic Cholangiocarcinoma. Cancers (Basel). 2021 Nov 15; 13(22).Cancers (Basel)2021-11-15T00:00:002021Oncogenic KRAS Requires Complete Loss of BAP1 Function for Development of Murine Intrahepatic Cholangiocarcinoma.true1ProfessorProfessortrue1ProfessorProfessortrue1Assistant ProfessorAssistant Professortrue1ProfessorProfessortrue1InstructorInstructortrue1Associate ProfessorAssociate Professortrue1Assistant ProfessorAssistant Professortrue1ProfessorProfessortrue1Assistant ProfessorAssistant Professortrue1Assistant ProfessorAssistant Professor