GUILIN TANG

TitleAssistant Professor
InstitutionMD Anderson
DepartmentHematopathology
Address1515 Holcombe Blvd
Houston TX 77030-4009
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    1. Tang G, Li S, Toruner GA, Jain P, Tang Z, Hu S, Xu J, Cheng J, Robinson M, Vega F, Medeiros LJ. Clinical impact of 5'MYC or 3'MYC gain/loss detected by FISH in patients with aggressive B-cell lymphomas. Cancer Genet. 2023 04; 272-273:1-8. PMID: 36566629.
      Citations:    Fields:    Translation:Humans
    2. Tang G, Zou Y, Wang SA, Borthakur G, Toruner G, Hu S, Li S, Xu J, Medeiros LJ, Tang Z. 3'CBFB deletion in CBFB-rearranged acute myeloid leukemia retains morphological features associated with inv(16), but patients have higher risk of relapse and may require stem cell transplant. Ann Hematol. 2022 Apr; 101(4):847-854. PMID: 35184217.
      Citations:    Fields:    Translation:HumansCells
    3. Tang G, Tam W, Short NJ, Bose P, Wu D, Hurwitz SN, Bagg A, Rogers HJ, Hsi ED, Quesada AE, Wang W, Miranda RN, Bueso-Ramos CE, Medeiros LJ, Nardi V, Hasserjian RP, Arber DA, Orazi A, Foucar K, Wang SA. Myeloid/lymphoid neoplasms with FLT3 rearrangement. Mod Pathol. 2021 09; 34(9):1673-1685. PMID: 33990705.
      Citations:    Fields:    Translation:Humans
    4. Huang JL, Fan RZ, Zou YH, Zhang L, Yin S, Tang GH. Salviplenoid A from Salvia plebeia attenuates acute lung inflammation via modulating NF-?B and Nrf2 signaling pathways. Phytother Res. 2021 Mar; 35(3):1559-1571. PMID: 33098234.
      Citations:    
    5. Tang G, Hu S, Wang SA, Xie W, Lin P, Xu J, Toruner G, Zhao M, Gu J, Doty M, Li S, Medeiros LJ, Tang Z. t(3;8)(q26.2;q24) Often Leads to MECOM/MYC Rearrangement and Is Commonly Associated with Therapy-Related Myeloid Neoplasms and/or Disease Progression. J Mol Diagn. 2019 03; 21(2):343-351. PMID: 30576868.
      Citations: 4     Fields:    Translation:Humans
    6. Lou LL, Li W, Zhou BH, Chen L, Weng HZ, Zou YH, Tang GH, Bu XZ, Yin S. (+)-Isobicyclogermacrenal and spathulenol from Aristolochia yunnanensis alleviate cardiac fibrosis by inhibiting transforming growth factor ?/small mother against decapentaplegic signaling pathway. Phytother Res. 2019 Jan; 33(1):214-223. PMID: 30375049.
      Citations:    
    7. Zhang JS, Tang YQ, Huang JL, Li W, Zou YH, Tang GH, Liu B, Yin S. Bioactive diterpenoids from Croton laevigatus. Phytochemistry. 2017 Dec; 144:151-158. PMID: 28934647.
      Citations:    
    8. Zou YH, Zhao L, Xu YK, Bao JM, Liu X, Zhang JS, Li W, Ahmed A, Yin S, Tang GH. Anti-inflammatory sesquiterpenoids from the Traditional Chinese Medicine Salvia plebeia: Regulates pro-inflammatory mediators through inhibition of NF-?B and Erk1/2 signaling pathways in LPS-induced Raw264.7 cells. J Ethnopharmacol. 2018 Jan 10; 210:95-106. PMID: 28847754.
      Citations: 9     Fields:    Translation:AnimalsCells
    9. Ahmed A, Li W, Zhang JS, Sam PH, Zou YH, Tang GH, Yin S. A new bisabolane sesquiterpenoid and a new abietane diterpenoid from Cephalotaxus sinensis. Nat Prod Res. 2018 Jan; 32(2):175-181. PMID: 28633536.
      Citations:    
    10. Tang G, Hidalgo Lopez JE, Wang SA, Hu S, Ma J, Pierce S, Zuo W, Carballo-Zarate AA, Yin CC, Tang Z, Li S, Medeiros LJ, Verstovsek S, Bueso-Ramos CE. Characteristics and clinical significance of cytogenetic abnormalities in polycythemia vera. Haematologica. 2017 09; 102(9):1511-1518. PMID: 28473622; PMCID: PMC5685217.
      Citations: 14     Fields:    Translation:HumansCells
    11. Li W, Zou YH, Ge MX, Lou LL, Xu YS, Ahmed A, Chen YY, Zhang JS, Tang GH, Yin S. Biscembranoids and Cembranoids from the Soft Coral Sarcophyton elegans. Mar Drugs. 2017 Mar 23; 15(4). PMID: 28333090; PMCID: PMC5408232.
      Citations:    
    12. Zou YH, Liu X, Liu YN, Tang GH, Yin S. A Novel Heterodimer from Crotalaria ferruginea. Nat Prod Commun. 2016 Jun; 11(6):793-4. PMID: 27534118.
      Citations:    
    13. Tang GH, Sun ZH, Zou YH, Yin S. New Cembrane-Type Diterpenoids from the South China Sea Soft Coral Sarcophyton ehrenbergi. Molecules. 2016 May 04; 21(5). PMID: 27153054; PMCID: PMC6273003.
      Citations:    
    14. Weiss VL, Wang XJ, Desai PA, Hu S, Yin CC, Tang G, Reddy NM, Medeiros LJ, Lin P, Li S. High-grade B-cell Lymphoma With MYC Rearrangement and Without BCL2 and BCL6 Rearrangements Is Associated With High P53 Expression and a Poor Prognosis. Am J Surg Pathol. 2016 Feb; 40(2):253-61. PMID: 26448193.
      Citations: 16     Fields:    Translation:HumansCells
    15. Tang G, Fu B, Hu S, Lu X, Tang Z, Li S, Jabbar K, Khoury JD, Medeiros LJ, Wang SA. Prognostic impact of acquisition of cytogenetic abnormalities during the course of chronic myelomonocytic leukemia. Am J Hematol. 2015 Oct; 90(10):882-7. PMID: 26148174.
      Citations: 5     Fields:    Translation:HumansCellsCTClinical Trials
    16. Tang GH, Chen ZW, Lin TT, Tan M, Gao XY, Bao JM, Cheng ZB, Sun ZH, Huang G, Yin S. Neolignans from Aristolochia fordiana Prevent Oxidative Stress-Induced Neuronal Death through Maintaining the Nrf2/HO-1 Pathway in HT22 Cells. J Nat Prod. 2015 Aug 28; 78(8):1894-903. PMID: 26226070.
      Citations: 2     Fields:    Translation:AnimalsCells
    17. Tang G, Goswami RS, Liang CS, Bueso-Ramos CE, Hu S, DiNardo C, Medeiros LJ. Isolated del(5q) in Patients Following Therapies for Various Malignancies May Not All Be Clinically Significant. Am J Clin Pathol. 2015 Jul; 144(1):78-86. PMID: 26071464.
      Citations: 4     Fields:    Translation:HumansCells
    18. Chen Z, Wang W, Rich A, Tang G, Hu S. Myeloid sarcoma as the initial presentation of chronic myelogenous leukemia, medullary chronic phase in era of tyrosine kinase inhibitors: A report of 11 cases. Am J Hematol. 2015 Aug; 90(8):E146-8. PMID: 25960187.
      Citations: 3     Fields:    Translation:Humans
    19. Liu H, Wang W, Tang G, Yin CC, Muzzafar T, Medeiros LJ, Hu S. Lymphomatous variant of hairy cell leukaemia: a distinctive presentation mimicking low-grade B-cell lymphoma. Histopathology. 2015 Nov; 67(5):740-5. PMID: 25809821.
      Citations: 1     Fields:    Translation:Humans
    20. Ouyang J, Goswami M, Tang G, Peng J, Ravandi F, Daver N, Routbort M, Konoplev S, Lin P, Medeiros LJ, Jorgensen JL, Wang SA. The clinical significance of negative flow cytometry immunophenotypic results in a morphologically scored positive bone marrow in patients following treatment for acute myeloid leukemia. Am J Hematol. 2015 Jun; 90(6):504-10. PMID: 25732229; PMCID: PMC5594737.
      Citations: 14     Fields:    Translation:HumansCells
    21. Goswami RS, Liang CS, Bueso-Ramos CE, Hu S, Goswami M, Yin CC, Lu G, Medeiros LJ, Tang G. Isolated +15 in bone marrow: disease-associated or a benign finding? Leuk Res. 2015 Jan; 39(1):72-6. PMID: 25435027.
      Citations: 4     Fields:    Translation:HumansCellsCTClinical Trials
    22. Tang G, DiNardo C, Zhang L, Ravandi F, Khoury JD, Huh YO, Muzzafar T, Medeiros LJ, Wang SA, Bueso-Ramos CE. MLL gene amplification in acute myeloid leukemia and myelodysplastic syndromes is associated with characteristic clinicopathological findings and TP53 gene mutation. Hum Pathol. 2015 Jan; 46(1):65-73. PMID: 25387813.
      Citations: 9     Fields:    Translation:HumansCells
    23. DiNardo CD, Tang G, Pemmaraju N, Wang SA, Pike A, Garcia-Manero G, Cortes J, Bueso-Ramos C, Kantarjian HM. Acute myeloid leukemia with t(10;11): a pathological entity with distinct clinical presentation. Clin Lymphoma Myeloma Leuk. 2015 Jan; 15(1):47-51. PMID: 25081372; PMCID: PMC4849878.
      Citations: 4     Fields:    Translation:HumansCells
    24. Tang G, Wang SA, Lu V, Lee HC, Qazilbash MH, Wang XI, Yin CC, Orlowski R, Wang Y, Patel A, Medeiros LJ, Lu G. Clinically silent clonal cytogenetic abnormalities arising in patients treated for lymphoid neoplasms. Leuk Res. 2014 Aug; 38(8):896-900. PMID: 24939217.
      Citations: 3     Fields:    Translation:Humans
    25. Tang G, Zhang L, Fu B, Hu J, Lu X, Hu S, Patel A, Goswami M, Khoury JD, Garcia-Manero G, Medeiros LJ, Wang SA. Cytogenetic risk stratification of 417 patients with chronic myelomonocytic leukemia from a single institution. Am J Hematol. 2014 Aug; 89(8):813-8. PMID: 24782398; PMCID: PMC4354712.
      Citations: 28     Fields:    Translation:HumansCells
    26. Tang G, Lu X, Wang SA, Roney EK, Zhang L, Hu S, Lu G, Medeiros LJ, Patel A. Homozygous inv(11)(q21q23) and MLL gene rearrangement in two patients with myeloid neoplasms. Int J Clin Exp Pathol. 2014; 7(6):3196-201. PMID: 25031740; PMCID: PMC4097224.
      Citations: 3     Fields:    Translation:HumansCells
    27. Wang SA, Hutchinson L, Tang G, Chen SS, Miron PM, Huh YO, Jones DM, Bueso-Ramos C, Verstovsek S, Medeiros LJ, Miranda RN. Systemic mastocytosis with associated clonal hematological non-mast cell lineage disease: clinical significance and comparison of chomosomal abnormalities in SM and AHNMD components. Am J Hematol. 2013 Mar; 88(3):219-24. PMID: 23440662; PMCID: PMC4188390.
      Citations: 26     Fields:    Translation:HumansCells
    28. Wang XY, Tang GH, Yuan CM, Zhang Y, Zou T, Yu C, Zhao Q, Hao XJ, He HP. Aphagrandinoids A-D, cycloartane triterpenoids with antibacterial activities from Aphanamixis grandifolia. Fitoterapia. 2013 Mar; 85:64-8. PMID: 23313271.
      Citations: 4     Fields:    Translation:AnimalsCells
    29. Tang G, Banks HE, Sargent RL, Medeiros LJ, Abruzzo LV. Chronic lymphocytic leukemia with t(14;18)(q32;q21). Hum Pathol. 2013 Apr; 44(4):598-605. PMID: 23084581; PMCID: PMC7147002.
      Citations: 9     Fields:    Translation:HumansCells
    30. Liu D, Lin P, Hu Y, Zhou Y, Tang G, Powers L, Medeiros LJ, Jorgensen JL, Wang SA. Immunophenotypic heterogeneity of normal plasma cells: comparison with minimal residual plasma cell myeloma. J Clin Pathol. 2012 Sep; 65(9):823-9. PMID: 22685235.
      Citations: 17     Fields:    Translation:HumansCells
    31. Tang G, Jorgensen LJ, Zhou Y, Hu Y, Kersh M, Garcia-Manero G, Medeiros LJ, Wang SA. Multi-color CD34? progenitor-focused flow cytometric assay in evaluation of myelodysplastic syndromes in patients with post cancer therapy cytopenia. Leuk Res. 2012 Aug; 36(8):974-81. PMID: 22626984.
      Citations: 7     Fields:    Translation:HumansCells
    32. Tang G, Zuo Z, Thomas DA, Lin P, Liu D, Hu Y, Kantarjian HM, Bueso-Ramos C, Medeiros LJ, Wang SA. Precursor B-acute lymphoblastic leukemia occurring in patients with a history of prior malignancies: is it therapy-related? Haematologica. 2012 Jun; 97(6):919-25. PMID: 22207681; PMCID: PMC3366660.
      Citations: 20     Fields:    Translation:Humans
    33. Zhou Y, Tang G, Medeiros LJ, McDonnell TJ, Keating MJ, Wierda WG, Wang SA. Therapy-related myeloid neoplasms following fludarabine, cyclophosphamide, and rituximab (FCR) treatment in patients with chronic lymphocytic leukemia/small lymphocytic lymphoma. Mod Pathol. 2012 Feb; 25(2):237-45. PMID: 22080061.
      Citations: 24     Fields:    Translation:Humans
    34. Tang G, Wang SA, Menon M, Dresser K, Woda BA, Hao S. High-level CD34 expression on megakaryocytes independently predicts an adverse outcome in patients with myelodysplastic syndromes. Leuk Res. 2011 Jun; 35(6):766-70. PMID: 21367453.
      Citations: 2     Fields:    Translation:HumansCells
    35. Hasserjian RP, Zuo Z, Garcia C, Tang G, Kasyan A, Luthra R, Abruzzo LV, Kantarjian HM, Medeiros LJ, Wang SA. Acute erythroid leukemia: a reassessment using criteria refined in the 2008 WHO classification. Blood. 2010 Mar 11; 115(10):1985-92. PMID: 20040759; PMCID: PMC2942006.
      Citations: 33     Fields:    Translation:Humans
    36. Wang YH, Long CL, Yang FM, Wang X, Sun QY, Wang HS, Shi YN, Tang GH. Pyrrolidinoindoline alkaloids from Selaginella moellendorfii. J Nat Prod. 2009 Jun; 72(6):1151-4. PMID: 19422203.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    37. Tang G, Woods LJ, Wang SA, Brettler D, Andersen M, Miron PM, Pechet L, Woda BA, Hao S. Chronic basophilic leukemia: a rare form of chronic myeloproliferative neoplasm. Hum Pathol. 2009 Aug; 40(8):1194-9. PMID: 19427022.
      Citations: 8     Fields:    Translation:HumansCells
    38. Pozdnyakova O, Miron PM, Tang G, Walter O, Raza A, Woda B, Wang SA. Cytogenetic abnormalities in a series of 1,029 patients with primary myelodysplastic syndromes: a report from the US with a focus on some undefined single chromosomal abnormalities. Cancer. 2008 Dec 15; 113(12):3331-40. PMID: 18988232.
      Citations: 24     Fields:    Translation:Humans
    39. Wang SA, Tang G, Fadare O, Hao S, Raza A, Woda BA, Hasserjian RP. Erythroid-predominant myelodysplastic syndromes: enumeration of blasts from nonerythroid rather than total marrow cells provides superior risk stratification. Mod Pathol. 2008 Nov; 21(11):1394-402. PMID: 18839018.
      Citations: 14     Fields:    Translation:HumansCells
    40. Tang F, Tang G, Xiang J, Dai Q, Rosner MR, Lin A. The absence of NF-kappaB-mediated inhibition of c-Jun N-terminal kinase activation contributes to tumor necrosis factor alpha-induced apoptosis. Mol Cell Biol. 2002 Dec; 22(24):8571-9. PMID: 12446776; PMCID: PMC139858.
      Citations: 60     Fields:    Translation:HumansAnimalsCells
    41. Tang G, Minemoto Y, Dibling B, Purcell NH, Li Z, Karin M, Lin A. Inhibition of JNK activation through NF-kappaB target genes. Nature. 2001 Nov 15; 414(6861):313-7. PMID: 11713531.
      Citations: 247     Fields:    Translation:HumansAnimalsCells
    42. Tang G, Yang J, Minemoto Y, Lin A. Blocking caspase-3-mediated proteolysis of IKKbeta suppresses TNF-alpha-induced apoptosis. Mol Cell. 2001 Nov; 8(5):1005-16. PMID: 11741536.
      Citations: 33     Fields:    Translation:HumansCells
    43. Purcell NH, Tang G, Yu C, Mercurio F, DiDonato JA, Lin A. Activation of NF-kappa B is required for hypertrophic growth of primary rat neonatal ventricular cardiomyocytes. Proc Natl Acad Sci U S A. 2001 Jun 05; 98(12):6668-73. PMID: 11381115; PMCID: PMC34410.
      Citations: 109     Fields:    Translation:AnimalsCells
    44. De Novo MYC and BCL2 Double-hit B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL) in Pediatric and Young Adult Patients Associated with Poor Prognosis. Pediatric Hematology and Oncology. 32:535-547.
    45. Flow cytometry immunophenotypic findings in chronic myelomonocytic leukemia and its utility in monitoring treatment response. European Journal of Haematology. 95:168-176.
    46. Acute leukaemia and myelodysplastic syndromes with chromosomal rearrangement involving 11q23 locus, but not MLL gene. Journal of Clinical Pathology.
    47. TP53 mutation characteristics in therapy-related myelodysplastic syndromes and acute myeloid leukemia is similar to de novo diseases. Journal of Hematology and Oncology. 8.
    48. Cytogenetic evolution associated with disease progression in Hematopoietic neoplasms with t(8;22)(p11;q11)/BCR-FQFR1 rearrangement. JNCCN Journal of the National Comprehensive Cancer Network. 14:708-711.
    49. P53 expression correlates with poorer survival and augments the negative prognostic effect of MYC rearrangement, expression or concurrent MYC/BCL2 expression in diffuse large B-cell lymphoma. Modern Pathology.
    50. Simultaneous deletion of 3'ETV6 and 5' EWSR1 genes in blastic plasmacytoid dendritic cell neoplasm. Molecular Cytogenetics. 9.
    51. Chronic myelomonocytic leukemia with nucleophosmin (NPM1) mutation. European Journal of Haematology.
    52. MYC/BCL6 double-hit lymphoma (DHL). Histopathology.
    53. Distinguishing Between Hepatosplenic T-cell Lymphoma and γδ T-cell Large Granular Lymphocytic Leukemia. American Journal of Surgical Pathology.
    54. Chromosomal rearrangement involving 11q23 locus in chronic myelogenous leukemia. Journal of Hematology and Oncology. 8.
    55. Systemic mastocytosis with associated clonal hematological non-mast cell lineage disease. American Journal of Hematology.
    56. Tetraploidy/near-tetraploidy acute myeloid leukemia. Leukemia Research. 53:20-27.
    57. Risk stratification of chromosomal abnormalities in chronic myelogenous leukemia in the era of tyrosine kinase inhibitor therapy. Blood. 127:2742-2750.
    58. Stage, age, and EBV status impact outcomes of plasmablastic lymphoma patients. Journal of Hematology and Oncology. 8.
    59. Impact of trisomy 8 on treatment response and survival of patients with chronic myelogenous leukemia in the era of tyrosine kinase inhibitors. Leukemia.
    60. Role of complexity of variant Philadelphia chromosome in chronic myeloid leukemia in the era of tyrosine kinase inhibitor therapy. Annals of Hematology. 1-4.
    61. Clinical significance of newly emerged isolated del(20q) in patients following cytotoxic therapies. Modern Pathology.
    62. Human Pathology. 60:160-166.
    63. Philadelphia-positive dimorphic blasts in mixed-phenotype acute leukemia with TET2 mutation. American Journal of Hematology.
    64. The clinical significance of 8q24/MYC rearrangement in chronic lymphocytic leukemia. Modern Pathology.
    65. Double minute chromosomes in acute myeloid leukemia, myelodysplastic syndromes, and chronic myelomonocytic leukemia are associated with micronuclei, MYC or MLL amplification, and complex karyotype. Cancer genetics. 209:313-320.
    66. Newly emerged isolated Del(7q) in patients with prior cytotoxic therapies may not always be associated with therapy-related myeloid neoplasms. Modern Pathology.
    67. Sex chromosome loss after allogeneic hematopoietic stem cell transplant in patients with hematologic neoplasms. Molecular Cytogenetics. 9.
    68. Double inv(3)(q21q26.2) in acute myeloid leukemia is resulted from an acquired copy neutral loss of heterozygosity of chromosome 3q and associated with disease progression. Molecular Cytogenetics. 8.
    69. Prognostic impact of history of follicular lymphoma, induction regimen and stem cell transplant in patients with MYC/BCL2 double hit lymphoma. Oncotarget. 7:38122-38132.
    70. Jumping Translocations in Myeloid Malignancies Associated With Treatment Resistance and Poor Survival. Clinical Lymphoma, Myeloma and Leukemia. 15:556-562.
    71. Comprehensive analysis of factors impacting risks and outcomes of therapy-related myeloid neoplasms following breast cancer treatment. Leukemia.
    72. Synchronous del5q myelodysplastic syndrome (del5qMDS) and adult B-cell acute lymphoblastic leukemia (B-ALL) with TET2 and TP53 mutations. American Journal of Hematology. 91:354-355.
    73. Myelodysplastic syndromes following therapy with hypomethylating agents (HMAs). Leukemia and Lymphoma. 57:812-819.
    74. Del(20q) in patients with chronic lymphocytic leukemia. Modern Pathology. 28:1130-1137.
    75. Clinical significance of acquired loss of the X chromosome in bone marrow. Leukemia Research. 47:109-113.
    76. Acute Myeloid Leukemia With t(v;5q33) Is Associated With Poor Overall Survival and Often Lacks Myelodysplastic Features. Clinical Lymphoma, Myeloma and Leukemia. 15:S85-S90.
    77. Advances in B-lymphoblastic leukemia. Annals of Diagnostic Pathology.
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