EVANGELIAKOUTELOUEVANGELIA KOUTELOU9559KOUTELOU, EVANGELIAInstructorprns:coAuthorOfcoauthor ofFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressvivo:address1address line 1vivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provincevivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentDivisionvivo:hasResearchArearesearch areasvivo:hrJobTitleHR job titleInformation Resourcevivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:personInPositionpositionsPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonPO Box 389Smithville78957-0389TXEpigenetics & Molecular CarcinogenesisGeneticsMolecular & Cellular OncologySystems BiologyMD AndersonMIEN-CHIEHUNGMIEN-CHIE HUNG8427HUNG, MIEN-CHIEProfessorRICHARD RBEHRINGERRICHARD R BEHRINGER8600BEHRINGER, RICHARD RProfessorFERNANDO JOSEBENAVIDESFERNANDO JOSE BENAVIDES8767BENAVIDES, FERNANDO JOSEProfessorCOLLENE RJETERCOLLENE R JETER9219JETER, COLLENE RAssistant ProfessorBOYKOATANASSOVBOYKO ATANASSOV9391ATANASSOV, BOYKOAssistant ProfessorYUELUYUE LU9586LU, YUEAssistant ProfessorGORDON BMILLSGORDON B MILLS8620MILLS, GORDON BProfessor1.048080.00591351149research areas4.491070.03336769coauthor of23.18463.2407460similar to1119selected publicationsSHARON RDENTSHARON R DENT8542DENT, SHARON RProfessorAuthorship 2248001Authorship 229297218077452Koutelou E, Sato S, Tomomori-Sato C, Florens L, Swanson SK, Washburn MP, Kokkinaki M, Conaway RC, Conaway JW, Moschonas NKThe Journal of biological chemistryNeuralized-like 1 (Neurl1) targeted to the plasma membrane by N-myristoylation regulates the Notch ligand Jagged1. J Biol Chem. 2008 Feb 15; 283(7):3846-53.J Biol Chem2007-12-12T00:00:002007Neuralized-like 1 (Neurl1) targeted to the plasma membrane by N-myristoylation regulates the Notch ligand Jagged1.20974139Atanassov BS, Koutelou E, Dent SYFEBS lettersThe role of deubiquitinating enzymes in chromatin regulation. FEBS Lett. 2011 Jul 07; 585(13):2016-23.FEBS Lett2010-10-26T00:00:002010The role of deubiquitinating enzymes in chromatin regulation.Authorship 2434393Authorship 257007211997106Pavlopoulos E, Kokkinaki M, Koutelou E, Mitsiadis TA, Prinos P, Delidakis C, Kilpatrick MW, Tsipouras P, Moschonas NKBiochimica et biophysica actaCloning, chromosomal organization and expression analysis of Neurl, the mouse homolog of Drosophila melanogaster neuralized gene. Biochim Biophys Acta. 2002 Apr 12; 1574(3):375-82.Biochim Biophys Acta2002-04-12T00:00:002002Cloning, chromosomal organization and expression analysis of Neurl, the mouse homolog of Drosophila melanogaster neuralized gene.21628526Wilson MA, Koutelou E, Hirsch C, Akdemir K, Schibler A, Barton MC, Dent SYMolecular and cellular biologyUbp8 and SAGA regulate Snf1 AMP kinase activity. Mol Cell Biol. 2011 Aug; 31(15):3126-35.Mol Cell Biol2011-05-31T00:00:002011Ubp8 and SAGA regulate Snf1 AMP kinase activity.Authorship 2692191Authorship 270380220363118Koutelou E, Hirsch CL, Dent SYCurrent opinion in cell biologyMultiple faces of the SAGA complex. Curr Opin Cell Biol. 2010 Jun; 22(3):374-82.Curr Opin Cell Biol2010-04-02T00:00:002010Multiple faces of the SAGA complex.22449188Butler JS, Koutelou E, Schibler AC, Dent SYEpigenomicsHistone-modifying enzymes: regulators of developmental decisions and drivers of human disease. Epigenomics. 2012 Apr; 4(2):163-77.Epigenomics2012-04-01T00:00:002012Histone-modifying enzymes: regulators of developmental decisions and drivers of human disease.Authorship 294700225755283Lan X, Koutelou E, Schibler AC, Chen YC, Grant PA, Dent SYMolecular and cellular biologyPoly(Q) Expansions in ATXN7 Affect Solubility but Not Activity of the SAGA Deubiquitinating Module. Mol Cell Biol. 2015 May; 35(10):1777-87.Mol Cell Biol2015-03-09T00:00:002015Poly(Q) Expansions in ATXN7 Affect Solubility but Not Activity of the SAGA Deubiquitinating Module.74Professor10Assistant Professor54Instructor47Distinguished Service Professor27132940Atanassov BS, Mohan RD, Lan X, Kuang X, Lu Y, Lin K, McIvor E, Li W, Zhang Y, Florens L, Byrum SD, Mackintosh SG, Calhoun-Davis T, Koutelou E, Wang L, Tang DG, Tackett AJ, Washburn MP, Workman JL, Dent SYMolecular cellATXN7L3 and ENY2 Coordinate Activity of Multiple H2B Deubiquitinases Important for Cellular Proliferation and Tumor Growth. Mol Cell. 2016 05 19; 62(4):558-71.Mol Cell2016-04-28T00:00:002016ATXN7L3 and ENY2 Coordinate Activity of Multiple H2B Deubiquitinases Important for Cellular Proliferation and Tumor Growth.Authorship 849312Authorship 861798Genes and DevelopmentHistone H3K4 methylation regulates deactivation of the spindle assembly checkpoint through direct binding of Mad2. Genes and Development. 30:1187-1197.Histone H3K4 methylation regulates deactivation of the spindle assembly checkpoint through direct binding of Mad2Molecular CellATXN7L3 and ENY2 Coordinate Activity of Multiple H2B Deubiquitinases Important for Cellular Proliferation and Tumor Growth. Molecular Cell. ATXN7L3 and ENY2 Coordinate Activity of Multiple H2B Deubiquitinases Important for Cellular Proliferation and Tumor GrowthAuthorship 88778114D008325Disorders2044930.762535Mammary Neoplasms, ExperimentalD051548Chemicals & Drugs1344100.835965Histone AcetyltransferasesD050880Chemicals & Drugs631090.923354p300-CBP Transcription FactorsD010450Chemicals & Drugs1562200.877707EndopeptidasesAuthorship 9073512Authorship 9273802Authorship 937342127198228Schibler A, Koutelou E, Tomida J, Wilson-Pham M, Wang L, Lu Y, Cabrera AP, Chosed RJ, Li W, Li B, Shi X, Wood RD, Dent SYGenes & developmentHistone H3K4 methylation regulates deactivation of the spindle assembly checkpoint through direct binding of Mad2. Genes Dev. 2016 05 15; 30(10):1187-97.Genes Dev2016-05-15T00:00:002016Histone H3K4 methylation regulates deactivation of the spindle assembly checkpoint through direct binding of Mad2.29249668Wang L, Koutelou E, Hirsch C, McCarthy R, Schibler A, Lin K, Lu Y, Jeter C, Shen J, Barton MC, Dent SYRStem cell reportsGCN5 Regulates FGF Signaling and Activates Selective MYC Target Genes during Early Embryoid Body Differentiation. Stem Cell Reports. 2018 01 09; 10(1):287-299.Stem Cell Reports2017-12-14T00:00:002017GCN5 Regulates FGF Signaling and Activates Selective MYC Target Genes during Early Embryoid Body Differentiation.30718289Koutelou E, Wang L, Schibler AC, Chao HP, Kuang X, Lin K, Lu Y, Shen J, Jeter CR, Salinger A, Wilson M, Chen YC, Atanassov BS, Tang DG, Dent SYRDevelopment (Cambridge, England)USP22 controls multiple signaling pathways that are essential for vasculature formation in the mouse placenta. Development. 2019 02 22; 146(4).Development2019-02-22T00:00:002019USP22 controls multiple signaling pathways that are essential for vasculature formation in the mouse placenta.D018507Physiology46415000.616566Gene Expression Regulation, DevelopmentalDepartment of Molecular & Cellular BiologyMolecular & Cellular BiologyBaylor College of MedicineBERTO'MALLEYBERT O'MALLEY0.000000000000000.000000000000002464O'MALLEY, BERTDistinguished Service Professortrue1Distinguished Service ProfessorDistinguished Service ProfessorAuthorship 995726132730897Koutelou E, Farria AT, Dent SYRBiochimica et biophysica acta. Gene regulatory mechanismsComplex functions of Gcn5 and Pcaf in development and disease. Biochim Biophys Acta Gene Regul Mech. 2021 02; 1864(2):194609.Biochim Biophys Acta Gene Regul Mech2020-07-28T00:00:002020Complex functions of Gcn5 and Pcaf in development and disease.Authorship 1004757833168647Farria AT, Plummer JB, Salinger AP, Shen J, Lin K, Lu Y, McBride KM, Koutelou E, Dent SYRCancer researchTranscriptional Activation of MYC-Induced Genes by GCN5 Promotes B-cell Lymphomagenesis. Cancer Res. 2020 12 15; 80(24):5543-5553.Cancer Res2020-11-09T00:00:002020Transcriptional Activation of MYC-Induced Genes by GCN5 Promotes B-cell Lymphomagenesis.Authorship 10293391234503086Kuang X, McAndrew MJ, Mustachio LM, Chen YC, Atanassov BS, Lin K, Lu Y, Shen J, Salinger A, Macatee T, Dent SYR, Koutelou ECancersUsp22 Overexpression Leads to Aberrant Signal Transduction of Cancer-Related Pathways but Is Not Sufficient to Drive Tumor Formation in Mice. Cancers (Basel). 2021 Aug 25; 13(17).Cancers (Basel)2021-08-25T00:00:002021Usp22 Overexpression Leads to Aberrant Signal Transduction of Cancer-Related Pathways but Is Not Sufficient to Drive Tumor Formation in Mice.Authorship 1037194235016034Chen YC, Koutelou E, Dent SYRMolecular cellNow open: Evolving insights to the roles of lysine acetylation in chromatin organization and function. Mol Cell. 2022 02 17; 82(4):716-727.Mol Cell2022-01-10T00:00:002022Now open: Evolving insights to the roles of lysine acetylation in chromatin organization and function.Authorship 1043736135411082Koutelou E, Dent SYRNature cell biologyNavigating EMT with COMPASS and PRC2. Nat Cell Biol. 2022 Apr; 24(4):412-414.Nat Cell Biol2022-04-01T00:00:002022Navigating EMT with COMPASS and PRC2.Authorship 1087215638236941Kuang X, Salinger A, Benavides F, Muller WJ, Dent SYR, Koutelou EPloS oneUSP22 overexpression fails to augment tumor formation in MMTV-ERBB2 mice but loss of function impacts MMTV promoter activity. PLoS One. 2024; 19(1):e0290837.PLoS One2024-01-18T00:00:002024USP22 overexpression fails to augment tumor formation in MMTV-ERBB2 mice but loss of function impacts MMTV promoter activity.true1ProfessorProfessortrue1ProfessorProfessortrue1InstructorInstructortrue1Assistant ProfessorAssistant Professortrue1Assistant ProfessorAssistant Professortrue1ProfessorProfessortrue1Assistant ProfessorAssistant Professortrue1ProfessorProfessortrue1ProfessorProfessor