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KWONG K WONG

TitleProfessor
InstitutionMD Anderson
DepartmentGynecological Oncology & Reproductive Medicine
Address1515 Holcombe Blvd
Houston TX 77030-4009
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Ng CW, Tsang YTM, Gershenson DM, Wong KK. The prognostic value of MEK pathway-associated estrogen receptor signaling activity for female cancers. Br J Cancer. 2024 May; 130(11):1875-1884. PMID: 38582811; PMCID: PMC11130254.
      Citations: 3     Fields:    Translation:HumansCells
    2. Treekitkarnmongkol W, Solis LM, Sankaran D, Gagea M, Singh PK, Mistry R, Nguyen T, Kai K, Liu J, Sasai K, Jitsumori Y, Liu J, Nagao N, Stossi F, Mancini MA, Wistuba II, Thompson AM, Lee JM, Cadi?anos J, Wong KK, Abbott CM, Sahin AA, Liu S, Katayama H, Sen S. eEF1A2 promotes PTEN-GSK3?-SCF complex-dependent degradation of Aurora kinase A and is inactivated in breast cancer. Sci Signal. 2024 03 05; 17(826):eadh4475. PMID: 38442201.
      Citations: 1     Fields:    Translation:HumansAnimals
    3. Ng CW, Wong KK. Deep learning-enabled breast cancer endocrine response determination from H&E staining based on ESR1 signaling activity. Sci Rep. 2023 12 05; 13(1):21454. PMID: 38052873; PMCID: PMC10698147.
      Citations:    Fields:    Translation:Humans
    4. Ferri-Borgogno S, Zhu Y, Sheng J, Burks JK, Gomez JA, Wong KK, Wong STC, Mok SC. Spatial Transcriptomics Depict Ligand-Receptor Cross-talk Heterogeneity at the Tumor-Stroma Interface in Long-Term Ovarian Cancer Survivors. Cancer Res. 2023 05 02; 83(9):1503-1516. PMID: 36787106; PMCID: PMC10159916.
      Citations: 2     Fields:    Translation:HumansCells
    5. Pei XM, Wong HT, Ng SSM, Leung WW, Wong YN, Tsang HF, Chan AKC, Wong YKE, Yu ACS, Yim AKY, Cho WCS, Chan JKC, Wong KF, Luk JM, Tai WCS, Wong SCC. The diagnostic significance of CDH17-positive circulating tumor cells in patients with colorectal cancer. Expert Rev Mol Diagn. 2023 02; 23(2):171-179. PMID: 36744385.
      Citations: 1     Fields:    Translation:HumansCells
    6. Wong KK, Bateman NW, Ng CW, Tsang YTM, Sun CS, Celestino J, Nguyen TV, Malpica A, Hillman RT, Zhang J, Futreal PA, Rojas C, Conrads KA, Hood BL, Dalgard CL, Wilkerson MD, Phippen NT, Conrads TP, Maxwell GL, Sood AK, Gershenson DM. Integrated multi-omic analysis of low-grade ovarian serous carcinoma collected from short and long-term survivors. J Transl Med. 2022 12 17; 20(1):606. PMID: 36528667; PMCID: PMC9758924.
      Citations:    Fields:    Translation:Humans
    7. Corvigno S, Johnson AM, Wong KK, Cho MS, Afshar-Kharghan V, Menter DG, Sood AK. Novel Markers for Liquid Biopsies in Cancer Management: Circulating Platelets and Extracellular Vesicles. Mol Cancer Ther. 2022 07 05; 21(7):1067-1075. PMID: 35545008; PMCID: PMC10314793.
      Citations:    Fields:    Translation:HumansCells
    8. Ng CW, Wong KK. Impact of estrogen receptor expression on prognosis of ovarian cancer according to antibody clone used for immunohistochemistry: a meta-analysis. J Ovarian Res. 2022 May 24; 15(1):63. PMID: 35610648; PMCID: PMC9128086.
      Citations:    Fields:    Translation:HumansCells
    9. Gershenson DM, Sun CC, Westin SN, Eyada M, Cobb LP, Nathan LC, Sood AK, Malpica A, Hillman RT, Wong KK. The genomic landscape of low-grade serous ovarian/peritoneal carcinoma and its impact on clinical outcomes. Gynecol Oncol. 2022 06; 165(3):560-567. PMID: 35606067.
      Citations:    Fields:    Translation:Humans
    10. Zheng BH, Shen S, Wong KF, Gong ZJ, Sun WT, Ni XJ, Wang JW, Hu MY, Liu H, Ni XL, Liu HB, Luk JM, Suo T. Clinical correlation of cadherin-17 marker with advanced tumor stages and poor prognosis of cholangiocarcinoma. J Surg Oncol. 2021 Apr; 123(5):1253-1262. PMID: 33524213.
      Citations: 3     Fields:    Translation:Humans
    11. Kun EHS, Tsang YTM, Lin S, Pan S, Medapalli T, Malpica A, Richards JS, Gershenson DM, Wong KK. Differences in gynecologic tumor development in Amhr2-Cre mice with KRASG12D or KRASG12V mutations. Sci Rep. 2020 11 26; 10(1):20678. PMID: 33244099; PMCID: PMC7693266.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    12. Izaguirre DI, Ng CW, Kwan SY, Kun EH, Tsang YTM, Gershenson DM, Wong KK. The Role of GDF15 in Regulating the Canonical Pathways of the Tumor Microenvironment in Wild-Type p53 Ovarian Tumor and Its Response to Chemotherapy. Cancers (Basel). 2020 Oct 19; 12(10). PMID: 33086658; PMCID: PMC7650722.
      Citations: 2     
    13. Zhang L, Kwan SY, Wong KK, Solaman PT, Lu KH, Mok SC. Pathogenesis and Clinical Management of Uterine Serous Carcinoma. Cancers (Basel). 2020 Mar 14; 12(3). PMID: 32183290; PMCID: PMC7140057.
      Citations: 6     
    14. Kwan SY, Au-Yeung CL, Yeung TL, Rynne-Vidal A, Wong KK, Risinger JI, Lin HK, Schmandt RE, Yates MS, Mok SC, Lu KH. Ubiquitin Carboxyl-Terminal Hydrolase L1 (UCHL1) Promotes Uterine Serous Cancer Cell Proliferation and Cell Cycle Progression. Cancers (Basel). 2020 Jan 02; 12(1). PMID: 31906456; PMCID: PMC7016780.
      Citations: 9     
    15. Yeung TL, Tsai CC, Leung CS, Au Yeung CL, Thompson MS, Lu KH, Freedman RS, Birrer MJ, Wong KK, Mok SC. ISG15 Promotes ERK1 ISGylation, CD8+ T Cell Activation and Suppresses Ovarian Cancer Progression. Cancers (Basel). 2018 Nov 22; 10(12). PMID: 30469497; PMCID: PMC6316352.
      Citations: 10     
    16. Hisamatsu T, McGuire M, Wu SY, Rupaimoole R, Pradeep S, Bayraktar E, Noh K, Hu W, Hansen JM, Lyons Y, Gharpure KM, Nagaraja AS, Mangala LS, Mitamura T, Rodriguez-Aguayo C, Eun YG, Rose J, Bartholomeusz G, Ivan C, Lee JS, Matsuo K, Frumovitz M, Wong KK, Lopez-Berestein G, Sood AK. PRKRA/PACT Expression Promotes Chemoresistance of Mucinous Ovarian Cancer. Mol Cancer Ther. 2019 01; 18(1):162-172. PMID: 30305341; PMCID: PMC6318044.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    17. Padmanabhan A, Candelaria N, Wong KK, Nikolai BC, Lonard DM, O'Malley BW, Richards JS. USP15-dependent lysosomal pathway controls p53-R175H turnover in ovarian cancer cells. Nat Commun. 2018 03 28; 9(1):1270. PMID: 29593334; PMCID: PMC5871815.
      Citations: 32     Fields:    Translation:HumansCells
    18. Leung CS, Yeung TL, Yip KP, Wong KK, Ho SY, Mangala LS, Sood AK, Lopez-Berestein G, Sheng J, Wong ST, Birrer MJ, Mok SC. Cancer-associated fibroblasts regulate endothelial adhesion protein LPP to promote ovarian cancer chemoresistance. J Clin Invest. 2018 02 01; 128(2):589-606. PMID: 29251630; PMCID: PMC5785271.
      Citations: 51     Fields:    Translation:HumansAnimalsCells
    19. Yeung TL, Leung CS, Wong KK, Gutierrez-Hartmann A, Kwong J, Gershenson DM, Mok SC. ELF3 is a negative regulator of epithelial-mesenchymal transition in ovarian cancer cells. Oncotarget. 2017 Mar 07; 8(10):16951-16963. PMID: 28199976; PMCID: PMC5370013.
      Citations: 36     Fields:    Translation:HumansCells
    20. Wong KF, Liu AM, Hong W, Xu Z, Luk JM. Integrin a2?1 inhibits MST1 kinase phosphorylation and activates Yes-associated protein oncogenic signaling in hepatocellular carcinoma. Oncotarget. 2016 Nov 22; 7(47):77683-77695. PMID: 27765911; PMCID: PMC5363613.
      Citations: 25     Fields:    Translation:HumansCells
    21. Kwan SY, Cheng X, Tsang YT, Choi JS, Kwan SY, Izaguirre DI, Kwan HS, Gershenson DM, Wong KK. Loss of ARID1A expression leads to sensitivity to ROS-inducing agent elesclomol in gynecologic cancer cells. Oncotarget. 2016 Aug 30; 7(35):56933-56943. PMID: 27486766; PMCID: PMC5302963.
      Citations: 13     Fields:    Translation:HumansCells
    22. Au Yeung CL, Co NN, Tsuruga T, Yeung TL, Kwan SY, Leung CS, Li Y, Lu ES, Kwan K, Wong KK, Schmandt R, Lu KH, Mok SC. Exosomal transfer of stroma-derived miR21 confers paclitaxel resistance in ovarian cancer cells through targeting APAF1. Nat Commun. 2016 Mar 29; 7:11150. PMID: 27021436; PMCID: PMC4820618.
      Citations: 313     Fields:    Translation:HumansCells
    23. Ren YA, Mullany LK, Liu Z, Herron AJ, Wong KK, Richards JS. Mutant p53 Promotes Epithelial Ovarian Cancer by Regulating Tumor Differentiation, Metastasis, and Responsiveness to Steroid Hormones. Cancer Res. 2016 04 15; 76(8):2206-18. PMID: 26964623; PMCID: PMC4873372.
      Citations: 26     Fields:    Translation:Animals
    24. Gershenson DM, Sun CC, Wong KK. Impact of mutational status on survival in low-grade serous carcinoma of the ovary or peritoneum. Br J Cancer. 2015 Nov 03; 113(9):1254-8. PMID: 26484411; PMCID: PMC4815788.
      Citations: 21     Fields:    Translation:Humans
    25. Mullany LK, Wong KK, Marciano DC, Katsonis P, King-Crane ER, Ren YA, Lichtarge O, Richards JS. Specific TP53 Mutants Overrepresented in Ovarian Cancer Impact CNV, TP53 Activity, Responses to Nutlin-3a, and Cell Survival. Neoplasia. 2015 Oct; 17(10):789-803. PMID: 26585234; PMCID: PMC4656807.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    26. Crane EK, Kwan SY, Izaguirre DI, Tsang YT, Mullany LK, Zu Z, Richards JS, Gershenson DM, Wong KK. Nutlin-3a: A Potential Therapeutic Opportunity for TP53 Wild-Type Ovarian Carcinomas. PLoS One. 2015; 10(8):e0135101. PMID: 26248031; PMCID: PMC4527847.
      Citations: 20     Fields:    Translation:HumansCells
    27. Gershenson DM, Bodurka DC, Lu KH, Nathan LC, Milojevic L, Wong KK, Malpica A, Sun CC. Impact of Age and Primary Disease Site on Outcome in Women With Low-Grade Serous Carcinoma of the Ovary or Peritoneum: Results of a Large Single-Institution Registry of a Rare Tumor. J Clin Oncol. 2015 Aug 20; 33(24):2675-82. PMID: 26195696; PMCID: PMC4534528.
      Citations: 28     Fields:    Translation:Humans
    28. Leung CS, Yeung TL, Yip KP, Pradeep S, Balasubramanian L, Liu J, Wong KK, Mangala LS, Armaiz-Pena GN, Lopez-Berestein G, Sood AK, Birrer MJ, Mok SC. Calcium-dependent FAK/CREB/TNNC1 signalling mediates the effect of stromal MFAP5 on ovarian cancer metastatic potential. Nat Commun. 2014 Oct 03; 5:5092. PMID: 25277212; PMCID: PMC4185407.
      Citations: 56     Fields:    Translation:HumansCells
    29. Liu AM, Xu Z, Shek FH, Wong KF, Lee NP, Poon RT, Chen J, Luk JM. miR-122 targets pyruvate kinase M2 and affects metabolism of hepatocellular carcinoma. PLoS One. 2014; 9(1):e86872. PMID: 24466275; PMCID: PMC3900676.
      Citations: 65     Fields:    Translation:HumansCells
    30. Tsang YT, Deavers MT, Sun CC, Kwan SY, Kuo E, Malpica A, Mok SC, Gershenson DM, Wong KK. KRAS (but not BRAF) mutations in ovarian serous borderline tumour are associated with recurrent low-grade serous carcinoma. J Pathol. 2013 Dec; 231(4):449-56. PMID: 24549645; PMCID: PMC4095747.
      Citations: 48     Fields:    Translation:HumansCells
    31. Yeung TL, Leung CS, Wong KK, Samimi G, Thompson MS, Liu J, Zaid TM, Ghosh S, Birrer MJ, Mok SC. TGF-? modulates ovarian cancer invasion by upregulating CAF-derived versican in the tumor microenvironment. Cancer Res. 2013 Aug 15; 73(16):5016-28. PMID: 23824740; PMCID: PMC3745588.
      Citations: 185     Fields:    Translation:HumansCells
    32. Wong KK, Izaguirre DI, Kwan SY, King ER, Deavers MT, Sood AK, Mok SC, Gershenson DM. Poor survival with wild-type TP53 ovarian cancer? Gynecol Oncol. 2013 Sep; 130(3):565-9. PMID: 23800698; PMCID: PMC4059202.
      Citations: 25     Fields:    Translation:HumansCells
    33. Yong KJ, Gao C, Lim JS, Yan B, Yang H, Dimitrov T, Kawasaki A, Ong CW, Wong KF, Lee S, Ravikumar S, Srivastava S, Tian X, Poon RT, Fan ST, Luk JM, Dan YY, Salto-Tellez M, Chai L, Tenen DG. Oncofetal gene SALL4 in aggressive hepatocellular carcinoma. N Engl J Med. 2013 Jun 13; 368(24):2266-76. PMID: 23758232; PMCID: PMC3781214.
      Citations: 97     Fields:    Translation:HumansAnimalsCells
    34. Romero I, Sun CC, Wong KK, Bast RC, Gershenson DM. Low-grade serous carcinoma: new concepts and emerging therapies. Gynecol Oncol. 2013 Sep; 130(3):660-6. PMID: 23707670.
      Citations: 20     Fields:    Translation:Humans
    35. Song H, Kwan SY, Izaguirre DI, Zu Z, Tsang YT, Tung CS, King ER, Mok SC, Gershenson DM, Wong KK. PAX2 Expression in Ovarian Cancer. Int J Mol Sci. 2013 Mar 15; 14(3):6090-105. PMID: 23502471; PMCID: PMC3634442.
      Citations: 16     Fields:    
    36. Yang G, Mercado-Uribe I, Multani AS, Sen S, Shih IeM, Wong KK, Gershenson DM, Liu J. RAS promotes tumorigenesis through genomic instability induced by imbalanced expression of Aurora-A and BRCA2 in midbody during cytokinesis. Int J Cancer. 2013 Jul 15; 133(2):275-85. PMID: 23319376; PMCID: PMC3883442.
      Citations: 24     Fields:    Translation:HumansAnimalsCells
    37. Zaid TM, Yeung TL, Thompson MS, Leung CS, Harding T, Co NN, Schmandt RS, Kwan SY, Rodriguez-Aguay C, Lopez-Berestein G, Sood AK, Wong KK, Birrer MJ, Mok SC. Identification of FGFR4 as a potential therapeutic target for advanced-stage, high-grade serous ovarian cancer. Clin Cancer Res. 2013 Feb 15; 19(4):809-20. PMID: 23344261; PMCID: PMC3577959.
      Citations: 40     Fields:    Translation:HumansAnimalsCells
    38. Mullany LK, Liu Z, Wong KK, Deneke V, Ren YA, Herron A, Richards JS. Tumor repressor protein 53 and steroid hormones provide a new paradigm for ovarian cancer metastases. Mol Endocrinol. 2014 Jan; 28(1):127-37. PMID: 24264574; PMCID: PMC3874458.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    39. Sung WK, Zheng H, Li S, Chen R, Liu X, Li Y, Lee NP, Lee WH, Ariyaratne PN, Tennakoon C, Mulawadi FH, Wong KF, Liu AM, Poon RT, Fan ST, Chan KL, Gong Z, Hu Y, Lin Z, Wang G, Zhang Q, Barber TD, Chou WC, Aggarwal A, Hao K, Zhou W, Zhang C, Hardwick J, Buser C, Xu J, Kan Z, Dai H, Mao M, Reinhard C, Wang J, Luk JM. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet. 2012 May 27; 44(7):765-9. PMID: 22634754.
      Citations: 387     Fields:    Translation:HumansCells
    40. Mullany LK, Liu Z, King ER, Wong KK, Richards JS. Wild-type tumor repressor protein 53 (Trp53) promotes ovarian cancer cell survival. Endocrinology. 2012 Apr; 153(4):1638-48. PMID: 22396451; PMCID: PMC3320246.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    41. Rajendran P, Li F, Shanmugam MK, Kannaiyan R, Goh JN, Wong KF, Wang W, Khin E, Tergaonkar V, Kumar AP, Luk JM, Sethi G. Celastrol suppresses growth and induces apoptosis of human hepatocellular carcinoma through the modulation of STAT3/JAK2 signaling cascade in vitro and in vivo. Cancer Prev Res (Phila). 2012 Apr; 5(4):631-43. PMID: 22369852.
      Citations: 62     Fields:    Translation:HumansAnimalsCells
    42. King ER, Wong KK. Insulin-like growth factor: current concepts and new developments in cancer therapy. Recent Pat Anticancer Drug Discov. 2012 Jan; 7(1):14-30. PMID: 21875414; PMCID: PMC3724215.
      Citations: 36     Fields:    Translation:HumansAnimalsCells
    43. Matsuo K, Nishimura M, Bottsford-Miller JN, Huang J, Komurov K, Armaiz-Pena GN, Shahzad MM, Stone RL, Roh JW, Sanguino AM, Lu C, Im DD, Rosenshien NB, Sakakibara A, Nagano T, Yamasaki M, Enomoto T, Kimura T, Ram PT, Schmeler KM, Gallick GE, Wong KK, Frumovitz M, Sood AK. Targeting SRC in mucinous ovarian carcinoma. Clin Cancer Res. 2011 Aug 15; 17(16):5367-78. PMID: 21737505; PMCID: PMC4028171.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    44. Luk JM, Burchard J, Zhang C, Liu AM, Wong KF, Shek FH, Lee NP, Fan ST, Poon RT, Ivanovska I, Philippar U, Cleary MA, Buser CA, Shaw PM, Lee CN, Tenen DG, Dai H, Mao M. DLK1-DIO3 genomic imprinted microRNA cluster at 14q32.2 defines a stemlike subtype of hepatocellular carcinoma associated with poor survival. J Biol Chem. 2011 Sep 02; 286(35):30706-30713. PMID: 21737452; PMCID: PMC3162431.
      Citations: 74     Fields:    Translation:HumansCells
    45. King ER, Zu Z, Tsang YT, Deavers MT, Malpica A, Mok SC, Gershenson DM, Wong KK. The insulin-like growth factor 1 pathway is a potential therapeutic target for low-grade serous ovarian carcinoma. Gynecol Oncol. 2011 Oct; 123(1):13-8. PMID: 21726895; PMCID: PMC3171566.
      Citations: 23     Fields:    Translation:HumansCells
    46. King ER, Tung CS, Tsang YT, Zu Z, Lok GT, Deavers MT, Malpica A, Wolf JK, Lu KH, Birrer MJ, Mok SC, Gershenson DM, Wong KK. The anterior gradient homolog 3 (AGR3) gene is associated with differentiation and survival in ovarian cancer. Am J Surg Pathol. 2011 Jun; 35(6):904-12. PMID: 21451362; PMCID: PMC3095702.
      Citations: 44     Fields:    Translation:HumansCells
    47. Wong KK, Tsang YT, Deavers MT, Mok SC, Zu Z, Sun C, Malpica A, Wolf JK, Lu KH, Gershenson DM. BRAF mutation is rare in advanced-stage low-grade ovarian serous carcinomas. Am J Pathol. 2010 Oct; 177(4):1611-7. PMID: 20802181; PMCID: PMC2947258.
      Citations: 77     Fields:    Translation:Humans
    48. Burchard J, Zhang C, Liu AM, Poon RT, Lee NP, Wong KF, Sham PC, Lam BY, Ferguson MD, Tokiwa G, Smith R, Leeson B, Beard R, Lamb JR, Lim L, Mao M, Dai H, Luk JM. microRNA-122 as a regulator of mitochondrial metabolic gene network in hepatocellular carcinoma. Mol Syst Biol. 2010 Aug 24; 6:402. PMID: 20739924; PMCID: PMC2950084.
      Citations: 111     Fields:    Translation:HumansAnimalsCells
    49. Mine T, Matsueda S, Gao H, Li Y, Wong KK, Peoples GE, Ferrone S, Ioannides CG. Created Gli-1 duplex short-RNA (i-Gli-RNA) eliminates CD44 Hi progenitors of taxol-resistant ovarian cancer cells. Oncol Rep. 2010 Jun; 23(6):1537-43. PMID: 20428807; PMCID: PMC3426036.
      Citations: 7     Fields:    Translation:HumansCells
    50. Mok SC, Bonome T, Vathipadiekal V, Bell A, Johnson ME, Wong KK, Park DC, Hao K, Yip DK, Donninger H, Ozbun L, Samimi G, Brady J, Randonovich M, Pise-Masison CA, Barrett JC, Wong WH, Welch WR, Berkowitz RS, Birrer MJ. A gene signature predictive for outcome in advanced ovarian cancer identifies a survival factor: microfibril-associated glycoprotein 2. Cancer Cell. 2009 Dec 08; 16(6):521-32. PMID: 19962670; PMCID: PMC3008560.
      Citations: 129     Fields:    Translation:HumansCells
    51. Tung CS, Mok SC, Tsang YT, Zu Z, Song H, Liu J, Deavers MT, Malpica A, Wolf JK, Lu KH, Gershenson DM, Wong KK. PAX2 expression in low malignant potential ovarian tumors and low-grade ovarian serous carcinomas. Mod Pathol. 2009 Sep; 22(9):1243-50. PMID: 19525924; PMCID: PMC2736318.
      Citations: 32     Fields:    Translation:Humans
    52. Kwong J, Chan FL, Wong KK, Birrer MJ, Archibald KM, Balkwill FR, Berkowitz RS, Mok SC. Inflammatory cytokine tumor necrosis factor alpha confers precancerous phenotype in an organoid model of normal human ovarian surface epithelial cells. Neoplasia. 2009 Jun; 11(6):529-41. PMID: 19484142; PMCID: PMC2685442.
      Citations: 20     Fields:    Translation:HumansCells
    53. Adesina AM, Lopez-Terrada D, Wong KK, Gunaratne P, Nguyen Y, Pulliam J, Margolin J, Finegold MJ. Gene expression profiling reveals signatures characterizing histologic subtypes of hepatoblastoma and global deregulation in cell growth and survival pathways. Hum Pathol. 2009 Jun; 40(6):843-53. PMID: 19200578; PMCID: PMC2957366.
      Citations: 24     Fields:    Translation:HumansCells
    54. Wong KK. Recent developments in anti-cancer agents targeting the Ras/Raf/ MEK/ERK pathway. Recent Pat Anticancer Drug Discov. 2009 Jan; 4(1):28-35. PMID: 19149686.
      Citations: 49     Fields:    Translation:HumansAnimalsCells
    55. Wong KK. Oral-specific chemical carcinogenesis in mice: an exciting model for cancer prevention and therapy. Cancer Prev Res (Phila). 2009 Jan; 2(1):10-3. PMID: 19139012.
      Citations: 4     Fields:    Translation:HumansAnimals
    56. Mine T, Matsueda S, Li Y, Tokumitsu H, Gao H, Danes C, Wong KK, Wang X, Ferrone S, Ioannides CG. Breast cancer cells expressing stem cell markers CD44+ CD24 lo are eliminated by Numb-1 peptide-activated T cells. Cancer Immunol Immunother. 2009 Aug; 58(8):1185-94. PMID: 19048252; PMCID: PMC2726795.
      Citations: 31     Fields:    Translation:HumansCells
    57. Park DC, Yeo SG, Wilson MR, Yerbury JJ, Kwong J, Welch WR, Choi YK, Birrer MJ, Mok SC, Wong KK. Clusterin interacts with Paclitaxel and confer Paclitaxel resistance in ovarian cancer. Neoplasia. 2008 Sep; 10(9):964-72. PMID: 18714397; PMCID: PMC2517641.
      Citations: 19     Fields:    Translation:HumansCells
    58. Lin YG, Immaneni A, Merritt WM, Mangala LS, Kim SW, Shahzad MM, Tsang YT, Armaiz-Pena GN, Lu C, Kamat AA, Han LY, Spannuth WA, Nick AM, Landen CN, Wong KK, Gray MJ, Coleman RL, Bodurka DC, Brinkley WR, Sood AK. Targeting aurora kinase with MK-0457 inhibits ovarian cancer growth. Clin Cancer Res. 2008 Sep 01; 14(17):5437-46. PMID: 18765535; PMCID: PMC2766914.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    59. Shu Q, Wong KK, Su JM, Adesina AM, Yu LT, Tsang YT, Antalffy BC, Baxter P, Perlaky L, Yang J, Dauser RC, Chintagumpala M, Blaney SM, Lau CC, Li XN. Direct orthotopic transplantation of fresh surgical specimen preserves CD133+ tumor cells in clinically relevant mouse models of medulloblastoma and glioma. Stem Cells. 2008 Jun; 26(6):1414-24. PMID: 18403755.
      Citations: 84     Fields:    Translation:HumansAnimals
    60. Tung CS, Wong KK, Mok SC. Biomarker discovery in ovarian cancer. Womens Health (Lond). 2008 Jan; 4:27-40. PMID: 19072449.
      Citations: 7     Fields:    Translation:Humans
    61. Wong KK, Lu KH, Malpica A, Bodurka DC, Shvartsman HS, Schmandt RE, Thornton AD, Deavers MT, Silva EG, Gershenson DM. Significantly greater expression of ER, PR, and ECAD in advanced-stage low-grade ovarian serous carcinoma as revealed by immunohistochemical analysis. Int J Gynecol Pathol. 2007 Oct; 26(4):404-9. PMID: 17885490.
      Citations: 35     Fields:    Translation:Humans
    62. Takei H, Yogeswaren ST, Wong KK, Mehta V, Chintagumpala M, Dauser RC, Lau CC, Adesina AM. Expression of oligodendroglial differentiation markers in pilocytic astrocytomas identifies two clinical subsets and shows a significant correlation with proliferation index and progression free survival. J Neurooncol. 2008 Jan; 86(2):183-90. PMID: 17690840.
      Citations: 15     Fields:    Translation:HumansCells
    63. Birrer MJ, Johnson ME, Hao K, Wong KK, Park DC, Bell A, Welch WR, Berkowitz RS, Mok SC. Whole genome oligonucleotide-based array comparative genomic hybridization analysis identified fibroblast growth factor 1 as a prognostic marker for advanced-stage serous ovarian adenocarcinomas. J Clin Oncol. 2007 Jun 01; 25(16):2281-7. PMID: 17538174.
      Citations: 60     Fields:    Translation:HumansCells
    64. Wong KK, Gershenson D. The continuum of serous tumors of low malignant potential and low-grade serous carcinomas of the ovary. Dis Markers. 2007; 23(5-6):377-87. PMID: 18057521; PMCID: PMC3850577.
      Citations: 12     Fields:    Translation:Humans
    65. Mok SC, Elias KM, Wong KK, Ho K, Bonome T, Birrer MJ. Biomarker discovery in epithelial ovarian cancer by genomic approaches. Adv Cancer Res. 2007; 96:1-22. PMID: 17161674.
      Citations: 6     Fields:    Translation:HumansAnimals
    66. Mok SC, Kwong J, Welch WR, Samimi G, Ozbun L, Bonome T, Birrer MJ, Berkowitz RS, Wong KK. Etiology and pathogenesis of epithelial ovarian cancer. Dis Markers. 2007; 23(5-6):367-76. PMID: 18057520; PMCID: PMC3851194.
      Citations: 18     Fields:    Translation:Humans
    67. Wong KK, Tsang YT, Chang YM, Su J, Di Francesco AM, Meco D, Riccardi R, Perlaky L, Dauser RC, Adesina A, Bhattacharjee M, Chintagumpala M, Lau CC. Genome-wide allelic imbalance analysis of pediatric gliomas by single nucleotide polymorphic allele array. Cancer Res. 2006 Dec 01; 66(23):11172-8. PMID: 17145861.
      Citations: 30     Fields:    Translation:HumansCells
    68. Li Y, Wong KK, Matsueda S, Efferson CL, Chang DZ, Ioannides CG, Tsuda N. Mitogen stimulation activates different signaling pathways in early- and late-divided T cells as revealed by cDNA microarray analysis. Int J Mol Med. 2006 Dec; 18(6):1127-39. PMID: 17089018.
      Citations: 3     Fields:    Translation:HumansCells
    69. Kwong J, Lee JY, Wong KK, Zhou X, Wong DT, Lo KW, Welch WR, Berkowitz RS, Mok SC. Candidate tumor-suppressor gene DLEC1 is frequently downregulated by promoter hypermethylation and histone hypoacetylation in human epithelial ovarian cancer. Neoplasia. 2006 Apr; 8(4):268-78. PMID: 16756719; PMCID: PMC1600675.
      Citations: 34     Fields:    Translation:HumansCells
    70. Wong KF, Ho JW. Identification of histidine-60 interaction with copper in activation of Chironomidae ferrochelatase. Protein Pept Lett. 2006; 13(5):443-6. PMID: 16800796.
      Citations:    Fields:    Translation:AnimalsCells
    71. Feltmate CM, Lee KR, Johnson M, Schorge JO, Wong KK, Hao K, Welch WR, Bell DA, Berkowitz RS, Mok SC. Whole-genome allelotyping identified distinct loss-of-heterozygosity patterns in mucinous ovarian and appendiceal carcinomas. Clin Cancer Res. 2005 Nov 01; 11(21):7651-7. PMID: 16278384.
      Citations: 6     Fields:    Translation:Humans
    72. Tsuda H, Ito YM, Ohashi Y, Wong KK, Hashiguchi Y, Welch WR, Berkowitz RS, Birrer MJ, Mok SC. Identification of overexpression and amplification of ABCF2 in clear cell ovarian adenocarcinomas by cDNA microarray analyses. Clin Cancer Res. 2005 Oct 01; 11(19 Pt 1):6880-8. PMID: 16203778.
      Citations: 21     Fields:    Translation:HumansCells
    73. Man TK, Chintagumpala M, Visvanathan J, Shen J, Perlaky L, Hicks J, Johnson M, Davino N, Murray J, Helman L, Meyer W, Triche T, Wong KK, Lau CC. Expression profiles of osteosarcoma that can predict response to chemotherapy. Cancer Res. 2005 Sep 15; 65(18):8142-50. PMID: 16166288.
      Citations: 50     Fields:    Translation:Humans
    74. Wong KK, Chang YM, Tsang YT, Perlaky L, Su J, Adesina A, Armstrong DL, Bhattacharjee M, Dauser R, Blaney SM, Chintagumpala M, Lau CC. Expression analysis of juvenile pilocytic astrocytomas by oligonucleotide microarray reveals two potential subgroups. Cancer Res. 2005 Jan 01; 65(1):76-84. PMID: 15665281.
      Citations: 27     Fields:    Translation:HumansCells
    75. Huddleston HG, Wong KK, Welch WR, Berkowitz RS, Mok SC. Clinical applications of microarray technology: creatine kinase B is an up-regulated gene in epithelial ovarian cancer and shows promise as a serum marker. Gynecol Oncol. 2005 Jan; 96(1):77-83. PMID: 15589584.
      Citations: 17     Fields:    Translation:HumansCells
    76. Tsuda H, Birrer MJ, Ito YM, Ohashi Y, Lin M, Lee C, Wong WH, Rao PH, Lau CC, Berkowitz RS, Wong KK, Mok SC. Identification of DNA copy number changes in microdissected serous ovarian cancer tissue using a cDNA microarray platform. Cancer Genet Cytogenet. 2004 Dec; 155(2):97-107. PMID: 15571795.
      Citations: 10     Fields:    Translation:HumansCells
    77. Tsang YT, Chang YM, Lu X, Rao PH, Lau CC, Wong KK. Amplification of MGC2177, PLAG1, PSMC6P, and LYN in a malignant mixed tumor of salivary gland detected by cDNA microarray with tyramide signal amplification. Cancer Genet Cytogenet. 2004 Jul 15; 152(2):124-8. PMID: 15262430.
      Citations: 3     Fields:    Translation:HumansCells
    78. Leung YK, Wong KF, Lee HK, Ho JW. Cloning and characterization of chironomidae ferrochelatase: copper activation of the purified ferrochelatase. Mol Cell Biochem. 2004 Jul; 262(1-2):225-31. PMID: 15532727.
      Citations:    Fields:    Translation:AnimalsCells
    79. Wong KK, Tsang YT, Shen J, Cheng RS, Chang YM, Man TK, Lau CC. Allelic imbalance analysis by high-density single-nucleotide polymorphic allele (SNP) array with whole genome amplified DNA. Nucleic Acids Res. 2004 May 17; 32(9):e69. PMID: 15148342; PMCID: PMC419627.
      Citations: 28     Fields:    Translation:HumansCells
    80. Kim JH, Herlyn D, Wong KK, Park DC, Schorge JO, Lu KH, Skates SJ, Cramer DW, Berkowitz RS, Mok SC. Identification of epithelial cell adhesion molecule autoantibody in patients with ovarian cancer. Clin Cancer Res. 2003 Oct 15; 9(13):4782-91. PMID: 14581349.
      Citations: 29     Fields:    Translation:HumansCells
    81. Lipton MS, Pasa-Tolic' L, Anderson GA, Anderson DJ, Auberry DL, Battista JR, Daly MJ, Fredrickson J, Hixson KK, Kostandarithes H, Masselon C, Markillie LM, Moore RJ, Romine MF, Shen Y, Stritmatter E, Tolic' N, Udseth HR, Venkateswaran A, Wong KK, Zhao R, Smith RD. Global analysis of the Deinococcus radiodurans proteome by using accurate mass tags. Proc Natl Acad Sci U S A. 2002 Aug 20; 99(17):11049-54. PMID: 12177431; PMCID: PMC129300.
      Citations: 106     Fields:    Translation:Cells
    82. Kim JH, Skates SJ, Uede T, Wong KK, Schorge JO, Feltmate CM, Berkowitz RS, Cramer DW, Mok SC. Osteopontin as a potential diagnostic biomarker for ovarian cancer. JAMA. 2002 Apr 03; 287(13):1671-9. PMID: 11926891.
      Citations: 114     Fields:    Translation:HumansCells
    83. Mok SC, Chao J, Skates S, Wong K, Yiu GK, Muto MG, Berkowitz RS, Cramer DW. Prostasin, a potential serum marker for ovarian cancer: identification through microarray technology. J Natl Cancer Inst. 2001 Oct 03; 93(19):1458-64. PMID: 11584061.
      Citations: 69     Fields:    Translation:HumansCellsPHPublic Health
    84. Wong KK, Cheng RS, Mok SC. Identification of differentially expressed genes from ovarian cancer cells by MICROMAX cDNA microarray system. Biotechniques. 2001 Mar; 30(3):670-5. PMID: 11252802.
      Citations: 18     Fields:    Translation:HumansCells
    85. Jensen PK, Pasa-Tolic L, Peden KK, Martinovic S, Lipton MS, Anderson GA, Tolic N, Wong KK, Smith RD. Mass spectrometric detection for capillary isoelectric focusing separations of complex protein mixtures. Electrophoresis. 2000 Apr; 21(7):1372-80. PMID: 10826683.
      Citations: 11     Fields:    Translation:Cells
    86. Wong RM, Wong KK, Benson NR, McClelland M. Sample sequencing of a Salmonella typhimurium LT2 lambda library: comparison to the Escherichia coli K12 genome. FEMS Microbiol Lett. 1999 Apr 15; 173(2):411-23. PMID: 10227170.
      Citations: 7     Fields:    Translation:HumansCells
    87. Romine MF, Stillwell LC, Wong KK, Thurston SJ, Sisk EC, Sensen C, Gaasterland T, Fredrickson JK, Saffer JD. Complete sequence of a 184-kilobase catabolic plasmid from Sphingomonas aromaticivorans F199. J Bacteriol. 1999 Mar; 181(5):1585-602. PMID: 10049392; PMCID: PMC93550.
      Citations: 96     Fields:    Translation:CellsPHPublic Health
    88. Markillie LM, Varnum SM, Hradecky P, Wong KK. Targeted mutagenesis by duplication insertion in the radioresistant bacterium Deinococcus radiodurans: radiation sensitivities of catalase (katA) and superoxide dismutase (sodA) mutants. J Bacteriol. 1999 Jan; 181(2):666-9. PMID: 9882685; PMCID: PMC93425.
      Citations: 46     Fields:    Translation:Cells
    89. Wong KK, McClelland M, Stillwell LC, Sisk EC, Thurston SJ, Saffer JD. Identification and sequence analysis of a 27-kilobase chromosomal fragment containing a Salmonella pathogenicity island located at 92 minutes on the chromosome map of Salmonella enterica serovar typhimurium LT2. Infect Immun. 1998 Jul; 66(7):3365-71. PMID: 9632606; PMCID: PMC108353.
      Citations: 30     Fields:    Translation:Cells
    90. Mok SC, Chan WY, Wong KK, Cheung KK, Lau CC, Ng SW, Baldini A, Colitti CV, Rock CO, Berkowitz RS. DOC-2, a candidate tumor suppressor gene in human epithelial ovarian cancer. Oncogene. 1998 May 07; 16(18):2381-7. PMID: 9620555.
      Citations: 52     Fields:    Translation:HumansCells
    91. Wong KK, Markillie LM, Saffer JD. A novel method for producing partial restriction digestion of DNA fragments by PCR with 5-methyl-CTP. Nucleic Acids Res. 1997 Oct 15; 25(20):4169-71. PMID: 9321677; PMCID: PMC147012.
      Citations: 7     Fields:    Translation:Cells
    92. Wong KK, Stillwell LC, Dockery CA, Saffer JD. Use of tagged random hexamer amplification (TRHA) to clone and sequence minute quantities of DNA--application to a 180 kb plasmid isolated from Sphingomonas F199. Nucleic Acids Res. 1996 Oct 01; 24(19):3778-83. PMID: 8871558; PMCID: PMC146178.
      Citations: 8     Fields:    Translation:Cells
    93. Mok SC, Chan WY, Wong KK, Muto MG, Berkowitz RS. SPARC, an extracellular matrix protein with tumor-suppressing activity in human ovarian epithelial cells. Oncogene. 1996 May 02; 12(9):1895-901. PMID: 8649850.
      Citations: 42     Fields:    Translation:HumansAnimalsCells
    94. Wong KK, Wong RM, Rudd KE, McClelland M. High-resolution restriction map for a 240-kilobase region spanning 91 to 96 minutes on the Salmonella typhimurium LT2 chromosome. J Bacteriol. 1994 Sep; 176(18):5729-34. PMID: 8083165; PMCID: PMC196777.
      Citations: 2     Fields:    Translation:Cells
    95. Mok SC, Wong KK, Chan RK, Lau CC, Tsao SW, Knapp RC, Berkowitz RS. Molecular cloning of differentially expressed genes in human epithelial ovarian cancer. Gynecol Oncol. 1994 Feb; 52(2):247-52. PMID: 8314147.
      Citations: 54     Fields:    Translation:HumansCells
    96. Wong KK, McClelland M. Stress-inducible gene of Salmonella typhimurium identified by arbitrarily primed PCR of RNA. Proc Natl Acad Sci U S A. 1994 Jan 18; 91(2):639-43. PMID: 7507252; PMCID: PMC43004.
      Citations: 24     Fields:    Translation:Cells
    97. Wong KK, Kwan HS. Transcription of glpT of Escherichia coli K12 is regulated by anaerobiosis and fnr. FEMS Microbiol Lett. 1992 Jul 01; 73(1-2):15-8. PMID: 1521763.
      Citations: 5     Fields:    Translation:Cells
    98. Wong KK, McClelland M. Dissection of the Salmonella typhimurium genome by use of a Tn5 derivative carrying rare restriction sites. J Bacteriol. 1992 Jun; 174(11):3807-11. PMID: 1317382; PMCID: PMC206072.
      Citations: 11     Fields:    Translation:Cells
    99. Wong KK, McClelland M. A BlnI restriction map of the Salmonella typhimurium LT2 genome. J Bacteriol. 1992 Mar; 174(5):1656-61. PMID: 1311299; PMCID: PMC206563.
      Citations: 24     Fields:    Translation:Cells
    100. Wong KK, McClelland M. PCR with 5-methyl-dCTP replacing dCTP. Nucleic Acids Res. 1991 Mar 11; 19(5):1081-5. PMID: 1850509; PMCID: PMC333784.
      Citations: 12     Fields:    Translation:Cells
    101. Wong KK, Suen KL, Kwan HS. Transcription of pfl is regulated by anaerobiosis, catabolite repression, pyruvate, and oxrA: pfl::Mu dA operon fusions of Salmonella typhimurium. J Bacteriol. 1989 Sep; 171(9):4900-5. PMID: 2549003; PMCID: PMC210295.
      Citations: 4     Fields:    Translation:Cells
    102. Kwan HS, Chui HW, Wong KK. ack::Mu d1-8 (Apr lac) operon fusions of Salmonella typhimurium LT2. Mol Gen Genet. 1988 Jan; 211(1):183-5. PMID: 2830464.
      Citations: 10     Fields:    Translation:Cells
    103. Kwan HS, Wong KK. A general method for isolation of Mu d1-8(Aprlac) operon fusions in Salmonella typhimurium LT2 from Tn10 insertion strains: chlC::Mu d1-8. Mol Gen Genet. 1986 Nov; 205(2):221-4. PMID: 3027501.
      Citations: 4     Fields:    Translation:Cells
    104. Molecular Basis of Gynecologic Diseases. 465-487.
    105. Molecular signatures in ovarian cancer. 423-446.
    106. Impact of mutational status on survival in low-grade serous carcinoma of the ovary or peritoneum. British Journal of Cancer. 113:1254-1258.
    107. Loss of ARID1A expression leads to sensitivity to ROS-inducing agent elesclomol in gynecologic cancer cells. Oncotarget. 7:56933-56943.
    108. Specific TP53 Mutants Overrepresented in Ovarian Cancer Impact CNV, TP53 Activity, Responses to Nutlin-3a, and Cell Survival. Neoplasia (United States). 17:789-803.
    109. DNA methylation promotes paired box 2 expression via myeloid zinc finger 1 in endometrial cancer. Oncotarget. 7:84785-84797.
    110. Molecular Basis of Gynecologic Diseases. 309-322.
    111. DNA methylases as tools. Clinical Chemistry. 37:606.
    112. Identification of differentially expressed RNA in human ovarian carcinoma cells by arbitrarily primed PCR fingerprinting of total RNAs. International Journal of Oncology. 3:13-17.
    113. Mutant p53 promotes epithelial ovarian cancer by regulating tumor differentiation, metastasis, and responsiveness to steroid hormones. Cancer Research. 76:2206-2218.
    114. The efficacy of a novel vaccine approach using tumor cells that ectopically express a codon-optimized murine GM-CSF in a murine tumor model. Vaccine. 34:134-141.
    115. Exosomal transfer of stroma-derived miR21 confers paclitaxel resistance in ovarian cancer cells through targeting APAF1. Nature Communications. 7.
    116. Global visualization and alignments of whole bacterial genomes. IEEE Transactions on Visualization and Computer Graphics. 9:361-377.
    117. KDM4B and KDM4A promote endometrial cancer progression by regulating androgen receptor, c-myc, and p27kip1 . Oncotarget. 6:31702-31720.
    118. The molecular pathology of ovarian serous borderline tumors. Annals of Oncology. 27:i16-i19.
    119. Nutlin-3a. PLoS One. 10.
    120. Organic data memory using the DNA approach. Communications of the ACM. 46:95-98.
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