HONGZHANGHONG ZHANG9174ZHANG, HONGAssociate Professorprns:coAuthorOfcoauthor ofFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressvivo:address1address line 1vivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provincevivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentDivisionvivo:hasResearchArearesearch areasvivo:hrJobTitleHR job titleInformation Resourcevivo:linkAnchorTextlink anchor textvivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:personInPositionpositionsPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titleURLLinkvivo:webpagewebpagerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPerson1515 Holcombe BlvdHouston77030-4009TXAuthorship 1814948Authorship 18273410Authorship 18332510Authorship 18513211Authorship 1855724Authorship 1869164Authorship 1883356Authorship 1890357Authorship 19174013Authorship 19179512Authorship 19259711Authorship 1929995Authorship 19367814Authorship 1942944Authorship 19468523Authorship 19617410Breast Medical OncologyLeukemiaMolecular & Cellular OncologySystems BiologyMD AndersonMIEN-CHIEHUNGMIEN-CHIE HUNG8427HUNG, MIEN-CHIEProfessorLEIHUOLEI HUO9168HUO, LEIAssociate ProfessorNAOTO TUENONAOTO T UENO8465UENO, NAOTO TProfessorHAGOP MKANTARJIANHAGOP M KANTARJIAN8501KANTARJIAN, HAGOP MProfessorKELLY KHUNTKELLY K HUNT8555HUNT, KELLY KProfessorGORDON BMILLSGORDON B MILLS8620MILLS, GORDON BProfessor0.9825370.00370373191research areas0.3095210.023288641coauthor of17.68973.3440960similar to1143selected publicationsHUIYUANZHANGHUIYUAN ZHANG9402ZHANG, HUIYUANInstructorSHAO-CONGSUNSHAO-CONG SUN9405SUN, SHAO-CONGProfessorAuthorship 2304108Authorship 2344848Authorship 234847621668471Tang F, Wei B, Tian Z, Gilcrease MZ, Huo L, Albarracin CT, Resetkova E, Zhang H, Sahin A, Chen J, Bu H, Abraham S, Wu YHistopathologyInvasive mammary carcinoma with neuroendocrine differentiation: histological features and diagnostic challenges. Histopathology. 2011 Jul; 59(1):106-15.Histopathology2011-06-13T00:00:002011Invasive mammary carcinoma with neuroendocrine differentiation: histological features and diagnostic challenges.24119786Nayak A, Carkaci S, Gilcrease MZ, Liu P, Middleton LP, Bassett RL, Zhang J, Zhang H, Coyne RL, Bevers TB, Sneige N, Huo LClinical breast cancerBenign papillomas without atypia diagnosed on core needle biopsy: experience from a single institution and proposed criteria for excision. Clin Breast Cancer. 2013 Dec; 13(6):439-49.Clin Breast Cancer2013-10-08T00:00:002013Benign papillomas without atypia diagnosed on core needle biopsy: experience from a single institution and proposed criteria for excision.25074542Xiang DB, Wei B, Abraham SC, Huo L, Albarracin CT, Zhang H, Babiera G, Caudle AS, Akay CL, Rao P, Zhao YJ, Lu X, Wu YHuman pathologyMolecular cytogenetic characterization of mammary neuroendocrine carcinoma. Hum Pathol. 2014 Sep; 45(9):1951-6.Hum Pathol2014-06-18T00:00:002014Molecular cytogenetic characterization of mammary neuroendocrine carcinoma.Authorship 258845622963676Huo L, Zhang J, Gilcrease MZ, Gong Y, Wu Y, Zhang H, Resetkova E, Hunt KK, Deavers MTHistopathologyGross cystic disease fluid protein-15 and mammaglobin A expression determined by immunohistochemistry is of limited utility in triple-negative breast cancer. Histopathology. 2013 Jan; 62(2):267-74.Histopathology2012-09-11T00:00:002012Gross cystic disease fluid protein-15 and mammaglobin A expression determined by immunohistochemistry is of limited utility in triple-negative breast cancer.24136008Lynch SP, Lei X, Hsu L, Meric-Bernstam F, Buchholz TA, Zhang H, Hortob?gyi GN, Gonzalez-Angulo AM, Valero VThe oncologistBreast cancer multifocality and multicentricity and locoregional recurrence. Oncologist. 2013; 18(11):1167-73.Oncologist2013-10-17T00:00:002013Breast cancer multifocality and multicentricity and locoregional recurrence.25079324Wang Y, Waters J, Leung ML, Unruh A, Roh W, Shi X, Chen K, Scheet P, Vattathil S, Liang H, Multani A, Zhang H, Zhao R, Michor F, Meric-Bernstam F, Navin NENatureClonal evolution in breast cancer revealed by single nucleus genome sequencing. Nature. 2014 Aug 14; 512(7513):155-60.Nature2014-07-30T00:00:002014Clonal evolution in breast cancer revealed by single nucleus genome sequencing.25584488Gonzalez-Angulo AM, Parinyanitikul N, Lei X, Mittendorf EA, Zhang H, Valero V, Hunt KK, Hortobagyi GN, Chavez-MacGregor MBritish journal of cancerEffect of adjuvant trastuzumab among patients treated with anti-HER2-based neoadjuvant therapy. Br J Cancer. 2015 Feb 17; 112(4):630-5.Br J Cancer2015-01-13T00:00:002015Effect of adjuvant trastuzumab among patients treated with anti-HER2-based neoadjuvant therapy.25626809Chang EI, Chang EI, Ito R, Zhang H, Nguyen AT, Skoracki RJ, Hanasono MM, Crosby MA, Ueno NT, Hunt KKPlastic and reconstructive surgeryChallenging a traditional paradigm: 12-year experience with autologous free flap breast reconstruction for inflammatory breast cancer. Plast Reconstr Surg. 2015 Feb; 135(2):262e-269e.Plast Reconstr Surg2015-02-01T00:00:002015Challenging a traditional paradigm: 12-year experience with autologous free flap breast reconstruction for inflammatory breast cancer.74Professor54Instructor14Associate ProfessorBreast Surgical Oncology19874889Sun W, Tan X, Shi Y, Xu G, Mao R, Gu X, Fan Y, Yu Y, Burlingame S, Zhang H, Rednam SP, Lu X, Zhang T, Fu S, Cao G, Qin J, Yang JCellular signallingUSP11 negatively regulates TNFalpha-induced NF-kappaB activation by targeting on IkappaBalpha. Cell Signal. 2010 Mar; 22(3):386-94.Cell Signal2010-03-01T00:00:002010USP11 negatively regulates TNFalpha-induced NF-kappaB activation by targeting on IkappaBalpha.Authorship 37385415Authorship 3738694Authorship 3738705Authorship 3738856Authorship 3738871222750291Zhao Y, Liang L, Fan Y, Sun S, An L, Shi Z, Cheng J, Jia W, Sun W, Mori-Akiyama Y, Zhang H, Fu S, Yang JCellular signallingPPM1B negatively regulates antiviral response via dephosphorylating TBK1. Cell Signal. 2012 Nov; 24(11):2197-204.Cell Signal2012-06-30T00:00:002012PPM1B negatively regulates antiviral response via dephosphorylating TBK1.20038579Fan Y, Yu Y, Shi Y, Sun W, Xie M, Ge N, Mao R, Chang A, Xu G, Schneider MD, Zhang H, Fu S, Qin J, Yang JThe Journal of biological chemistryLysine 63-linked polyubiquitination of TAK1 at lysine 158 is required for tumor necrosis factor alpha- and interleukin-1beta-induced IKK/NF-kappaB and JNK/AP-1 activation. J Biol Chem. 2010 Feb 19; 285(8):5347-60.J Biol Chem2009-12-28T00:00:002009Lysine 63-linked polyubiquitination of TAK1 at lysine 158 is required for tumor necrosis factor alpha- and interleukin-1beta-induced IKK/NF-kappaB and JNK/AP-1 activation.Authorship 841722Authorship 843068Authorship 844642Authorship 845714Authorship 850369Authorship 851147Authorship 853475Authorship 854158Authorship 854337Authorship 855078Authorship 863178Authorship 863559Authorship 863819Authorship 864064Authorship 864234Authorship 865327Authorship 866080Scientific ReportsNext-generation proteasome inhibitor MLN9708 sensitizes breast cancer cells to doxorubicin-induced apoptosis. Scientific Reports. 6.Next-generation proteasome inhibitor MLN9708 sensitizes breast cancer cells to doxorubicin-induced apoptosisOncotargetSecond-generation proteasome inhibitor carfilzomib enhances doxorubicin-induced cytotoxicity and apoptosis in breast cancer cells. Oncotarget. 7:73697-73710.Second-generation proteasome inhibitor carfilzomib enhances doxorubicin-induced cytotoxicity and apoptosis in breast cancer cellsAnnals of Plastic SurgeryChoosing the optimal timing for contralateral symmetry procedures after unilateral free flap breast reconstruction. Annals of Plastic Surgery. 74:12-16.Choosing the optimal timing for contralateral symmetry procedures after unilateral free flap breast reconstructionPLoS OneThe status of STAT3 and STAT5 in human breast atypical ductal hyperplasia. PLoS One. 10.The status of STAT3 and STAT5 in human breast atypical ductal hyperplasiaAnnals of Surgical OncologyOptimization of Free-Flap Limb Salvage and Maximizing Function and Quality of Life Following Oncologic Resection. Annals of Surgical Oncology. 23:1036-1043.Optimization of Free-Flap Limb Salvage and Maximizing Function and Quality of Life Following Oncologic ResectionScientific ReportsMultiple CDK inhibitor dinaciclib suppresses neuroblastoma growth via inhibiting CDK2 and CDK9 activity. Scientific Reports. 6.Multiple CDK inhibitor dinaciclib suppresses neuroblastoma growth via inhibiting CDK2 and CDK9 activityHistopathologyGATA-binding protein 3 enhances the utility of gross cystic disease fluid protein-15 and mammaglobin A in triple-negative breast cancer by immunohistochemistry. Histopathology. GATA-binding protein 3 enhances the utility of gross cystic disease fluid protein-15 and mammaglobin A in triple-negative breast cancer by immunohistochemistryScientific ReportsNovel ALK inhibitor AZD3463 inhibits neuroblastoma growth by overcoming crizotinib resistance and inducing apoptosis. Scientific Reports. 6.Novel ALK inhibitor AZD3463 inhibits neuroblastoma growth by overcoming crizotinib resistance and inducing apoptosisApoptosisMTOR ATP-competitive inhibitor INK128 inhibits neuroblastoma growth via blocking mTORC signaling. Apoptosis. 20:50-62.MTOR ATP-competitive inhibitor INK128 inhibits neuroblastoma growth via blocking mTORC signalingPlastic and Reconstructive SurgeryDeciphering the Sensitivity and Specificity of the Implantable Doppler in Free Flap Monitoring. Plastic and Reconstructive Surgery. Deciphering the Sensitivity and Specificity of the Implantable Doppler in Free Flap MonitoringInternational Journal of OncologyThe novel mTORC1/2 dual inhibitor INK128 enhances radiosensitivity of breast cancer cell line MCF-7. International Journal of Oncology. 49:1039-1045.The novel mTORC1/2 dual inhibitor INK128 enhances radiosensitivity of breast cancer cell line MCF-7Nature GeneticsPunctuated copy number evolution and clonal stasis in triple-negative breast cancer. Nature Genetics. Punctuated copy number evolution and clonal stasis in triple-negative breast cancerOncotargetNovel Src/Abl tyrosine kinase inhibitor bosutinib suppresses neuroblastoma growth via inhibiting Src/Abl signaling. Oncotarget. 8:1469-1480.Novel Src/Abl tyrosine kinase inhibitor bosutinib suppresses neuroblastoma growth via inhibiting Src/Abl signalingScientific ReportsTAK1 inhibitor NG25 enhances doxorubicin-mediated apoptosis in breast cancer cells. Scientific Reports. 6.TAK1 inhibitor NG25 enhances doxorubicin-mediated apoptosis in breast cancer cellsScientific ReportsWip1 inhibitor GSK2830371 inhibits neuroblastoma growth by inducing Chk2/p53-mediated apoptosis. Scientific Reports. 6.Wip1 inhibitor GSK2830371 inhibits neuroblastoma growth by inducing Chk2/p53-mediated apoptosisAnnals of Plastic SurgeryComprehensive evaluation of risk factors and management of impending flap loss in 2138 breast free flaps. Annals of Plastic Surgery. Comprehensive evaluation of risk factors and management of impending flap loss in 2138 breast free flapsHead and NeckAnalysis of risk factors for flap loss and salvage in free flap head and neck reconstruction. Head and Neck. Analysis of risk factors for flap loss and salvage in free flap head and neck reconstructiontrue1ProfessorProfessorD016328Chemicals & DrugsPhysiology60215430.590431NF-kappa BD054875Phenomena2775750.794134UbiquitinationD020930Chemicals & Drugs1221900.899816MAP Kinase Kinase KinasesD008239Chemicals & Drugs2254230.822722LysineImmunologyPathologyDepartment of MedicineDepartment of PediatricsMedicine-Hematology & OncologyBaylor College of MedicineHANUMANTHAPULIVARTHIHANUMANTHA PULIVARTHI0.000000000000000.00000000000000108PULIVARTHI, HANUMANTHAProfessorSUSANHILSENBECKSUSAN HILSENBECK0.000000000000000.000000000000003634HILSENBECK, SUSANProfessorD061108Activities & BehaviorsConcepts & Ideas1122030.723325Social Media23700229Fan Y, Cheng J, Vasudevan SA, Patel RH, Liang L, Xu X, Zhao Y, Jia W, Lu F, Zhang H, Nuchtern JG, Kim ES, Yang JApoptosis : an international journal on programmed cell deathTAK1 inhibitor 5Z-7-oxozeaenol sensitizes neuroblastoma to chemotherapy. Apoptosis. 2013 Oct; 18(10):1224-34.Apoptosis2013-10-01T00:00:002013TAK1 inhibitor 5Z-7-oxozeaenol sensitizes neuroblastoma to chemotherapy.24136231Fan YH, Cheng J, Vasudevan SA, Dou J, Zhang H, Patel RH, Ma IT, Rojas Y, Zhao Y, Yu Y, Zhang H, Shohet JM, Nuchtern JG, Kim ES, Yang JCell death & diseaseUSP7 inhibitor P22077 inhibits neuroblastoma growth via inducing p53-mediated apoptosis. Cell Death Dis. 2013 Oct 17; 4:e867.Cell Death Dis2013-10-17T00:00:002013USP7 inhibitor P22077 inhibits neuroblastoma growth via inducing p53-mediated apoptosis.true1ProfessorProfessorhttp://http://txch.org/doctors/dr-pulivarthi-rao/24122835Fan Y, Ge N, Wang X, Sun W, Mao R, Bu W, Creighton CJ, Zheng P, Vasudevan S, An L, Yang J, Zhao YJ, Zhang H, Li XN, Rao PH, Leung E, Lu YJ, Gray JW, Schiff R, Hilsenbeck SG, Osborne CK, Yang J, Zhang HThe Journal of pathologyAmplification and over-expression of MAP3K3 gene in human breast cancer promotes formation and survival of breast cancer cells. J Pathol. 2014 Jan; 232(1):75-86.J Pathol2014-01-01T00:00:002014Amplification and over-expression of MAP3K3 gene in human breast cancer promotes formation and survival of breast cancer cells.21130870Fan Y, Yu Y, Mao R, Zhang H, Yang JCellular signallingTAK1 Lys-158 but not Lys-209 is required for IL-1?-induced Lys63-linked TAK1 polyubiquitination and IKK/NF-?B activation. Cell Signal. 2011 Apr; 23(4):660-5.Cell Signal2010-12-03T00:00:002010TAK1 Lys-158 but not Lys-209 is required for IL-1?-induced Lys63-linked TAK1 polyubiquitination and IKK/NF-?B activation.22981905Liang L, Fan Y, Cheng J, Cheng D, Zhao Y, Cao B, Ma L, An L, Jia W, Su X, Yang J, Zhang HCellular signallingTAK1 ubiquitination regulates doxorubicin-induced NF-?B activation. Cell Signal. 2013 Jan; 25(1):247-54.Cell Signal2012-09-07T00:00:002012TAK1 ubiquitination regulates doxorubicin-induced NF-?B activation.23907581An L, Jia W, Yu Y, Zou N, Liang L, Zhao Y, Fan Y, Cheng J, Shi Z, Xu G, Li G, Yang J, Zhang HScientific reportsLys63-linked polyubiquitination of BRAF at lysine 578 is required for BRAF-mediated signaling. Sci Rep. 2013; 3:2344.Sci Rep2013-01-01T00:00:002013Lys63-linked polyubiquitination of BRAF at lysine 578 is required for BRAF-mediated signaling.24381245Haricharan S, Dong J, Hein S, Reddy JP, Du Z, Toneff M, Holloway K, Hilsenbeck SG, Huang S, Atkinson R, Woodward W, Jindal S, Borges VF, Gutierrez C, Zhang H, Schedin PJ, Osborne CK, Tweardy DJ, Li YeLifeMechanism and preclinical prevention of increased breast cancer risk caused by pregnancy. Elife. 2013 Dec 31; 2:e00996.Elife2013-12-31T00:00:002013Mechanism and preclinical prevention of increased breast cancer risk caused by pregnancy.19465115Sun W, Li H, Yu Y, Fan Y, Grabiner BC, Mao R, Ge N, Zhang H, Fu S, Lin X, Yang JCellular signallingMEKK3 is required for lysophosphatidic acid-induced NF-kappaB activation. Cell Signal. 2009 Oct; 21(10):1488-94.Cell Signal2009-05-22T00:00:002009MEKK3 is required for lysophosphatidic acid-induced NF-kappaB activation.22406003Fan Y, Shi Y, Liu S, Mao R, An L, Zhao Y, Zhang H, Zhang F, Xu G, Qin J, Yang JCellular signallingLys48-linked TAK1 polyubiquitination at lysine-72 downregulates TNFa-induced NF-?B activation via mediating TAK1 degradation. Cell Signal. 2012 Jul; 24(7):1381-9.Cell Signal2012-03-03T00:00:002012Lys48-linked TAK1 polyubiquitination at lysine-72 downregulates TNFa-induced NF-?B activation via mediating TAK1 degradation.20837137Mao R, Fan Y, Mou Y, Zhang H, Fu S, Yang JCellular signallingTAK1 lysine 158 is required for TGF-?-induced TRAF6-mediated Smad-independent IKK/NF-?B and JNK/AP-1 activation. Cell Signal. 2011 Jan; 23(1):222-7.Cell Signal2010-09-16T00:00:002010TAK1 lysine 158 is required for TGF-?-induced TRAF6-mediated Smad-independent IKK/NF-?B and JNK/AP-1 activation.Authorship 1049998135805646Zhang HT, Tham JS, Waheed MInternational journal of environmental research and public healthThe Effects of Receiving and Expressing Health Information on Social Media during the COVID-19 Infodemic: An Online Survey among Malaysians. Int J Environ Res Public Health. 2022 06 29; 19(13).Int J Environ Res Public Health2022-06-29T00:00:002022The Effects of Receiving and Expressing Health Information on Social Media during the COVID-19 Infodemic: An Online Survey among Malaysians.true1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1Associate ProfessorAssociate Professortrue1Associate ProfessorAssociate Professortrue1InstructorInstructortrue1ProfessorProfessor19706600Fan Y, Mao R, Zhao Y, Yu Y, Sun W, Song P, Shi Z, Zhang D, Yvon E, Zhang H, Fu S, Yang JThe Journal of biological chemistryTumor necrosis factor-alpha induces RelA degradation via ubiquitination at lysine 195 to prevent excessive nuclear factor-kappaB activation. J Biol Chem. 2009 Oct 23; 284(43):29290-7.J Biol Chem2009-08-25T00:00:002009Tumor necrosis factor-alpha induces RelA degradation via ubiquitination at lysine 195 to prevent excessive nuclear factor-kappaB activation.21331078Fan YH, Yu Y, Mao RF, Tan XJ, Xu GF, Zhang H, Lu XB, Fu SB, Yang JCell death and differentiationUSP4 targets TAK1 to downregulate TNFa-induced NF-?B activation. Cell Death Differ. 2011 Oct; 18(10):1547-60.Cell Death Differ2011-02-18T00:00:002011USP4 targets TAK1 to downregulate TNFa-induced NF-?B activation.24493797Fan Y, Mao R, Yu Y, Liu S, Shi Z, Cheng J, Zhang H, An L, Zhao Y, Xu X, Chen Z, Kogiso M, Zhang D, Zhang H, Zhang P, Jung JU, Li X, Xu G, Yang JThe Journal of experimental medicineUSP21 negatively regulates antiviral response by acting as a RIG-I deubiquitinase. J Exp Med. 2014 Feb 10; 211(2):313-28.J Exp Med2014-02-03T00:00:002014USP21 negatively regulates antiviral response by acting as a RIG-I deubiquitinase.24556694Cheng J, Fan YH, Xu X, Zhang H, Dou J, Tang Y, Zhong X, Rojas Y, Yu Y, Zhao Y, Vasudevan SA, Zhang H, Nuchtern JG, Kim ES, Chen X, Lu F, Yang JCell death & diseaseA small-molecule inhibitor of UBE2N induces neuroblastoma cell death via activation of p53 and JNK pathways. Cell Death Dis. 2014 Feb 20; 5:e1079.Cell Death Dis2014-02-20T00:00:002014A small-molecule inhibitor of UBE2N induces neuroblastoma cell death via activation of p53 and JNK pathways.Pediatrics-Hem-Onc Res/Core Labs