XIAOHUASUXIAOHUA SU8935SU, XIAOHUAAssistant Professorprns:coAuthorOfcoauthor ofFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressvivo:address1address line 1vivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provincevivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentDivisionvivo:hasResearchArearesearch areasvivo:hrJobTitleHR job titleInformation Resourcevivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:personInPositionpositionsPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPerson6565 MD Anderson BlvdHouston77030TXAuthorship 1700103Authorship 1733751Authorship 1748492Authorship 1815671Authorship 1860151Authorship 1950892Authorship 195730511150520Wakabayashi S, Pang T, Su X, Shigekawa MFEBS lettersSecond mutations rescue point mutant of the Na(+)/H(+) exchanger NHE1 showing defective surface expression. FEBS Lett. 2000 Dec 29; 487(2):257-61.FEBS Lett2000-12-29T00:00:002000Second mutations rescue point mutant of the Na(+)/H(+) exchanger NHE1 showing defective surface expression.12549930Su X, Pang T, Wakabayashi S, Shigekawa MBiochemistryEvidence for involvement of the putative first extracellular loop in differential volume sensitivity of the Na+/H+ exchangers NHE1 and NHE2. Biochemistry. 2003 Feb 04; 42(4):1086-94.Biochemistry2003-02-04T00:00:002003Evidence for involvement of the putative first extracellular loop in differential volume sensitivity of the Na+/H+ exchangers NHE1 and NHE2.23589370Liao JM, Zhang Y, Liao W, Zeng SX, Su X, Flores ER, Lu HThe Journal of biological chemistryI?B kinase ? (IKK?) inhibits p63 isoform ? (TAp63?) transcriptional activity. J Biol Chem. 2013 Jun 21; 288(25):18184-93.J Biol Chem2013-04-15T00:00:002013I?B kinase ? (IKK?) inhibits p63 isoform ? (TAp63?) transcriptional activity.Cancer BiologyExperimental Radiation OncologyExperimental TherapeuticsGeneticsLeukemiaMolecular & Cellular OncologySystems BiologyMD AndersonMIEN-CHIEHUNGMIEN-CHIE HUNG8427HUNG, MIEN-CHIEProfessorGREGORY NFULLERGREGORY N FULLER8573FULLER, GREGORY NProfessorGORDON BMILLSGORDON B MILLS8620MILLS, GORDON BProfessorRONALD ADEPINHORONALD A DEPINHO9729DEPINHO, RONALD AProfessorSADHANMAJUMDERSADHAN MAJUMDER8451MAJUMDER, SADHANProfessor1.43840.00509936204research areas0.6098810.016660124coauthor of16.73093.933760similar to1122selected publicationsGEORGE ACALINGEORGE A CALIN9408CALIN, GEORGE AProfessorMARINAKONOPLEVAMARINA KONOPLEVA8702KONOPLEVA, MARINAProfessorAuthorship 2178692Authorship 2210001Authorship 2272521Authorship 233398111350981Pang T, Su X, Wakabayashi S, Shigekawa MThe Journal of biological chemistryCalcineurin homologous protein as an essential cofactor for Na+/H+ exchangers. J Biol Chem. 2001 May 18; 276(20):17367-72.J Biol Chem2001-02-28T00:00:002001Calcineurin homologous protein as an essential cofactor for Na+/H+ exchangers.15340064Su X, Kameoka S, Lentz S, Majumder SMolecular and cellular biologyActivation of REST/NRSF target genes in neural stem cells is sufficient to cause neuronal differentiation. Mol Cell Biol. 2004 Sep; 24(18):8018-25.Mol Cell Biol2004-09-01T00:00:002004Activation of REST/NRSF target genes in neural stem cells is sufficient to cause neuronal differentiation.19570515Su X, Paris M, Gi YJ, Tsai KY, Cho MS, Lin YL, Biernaskie JA, Sinha S, Prives C, Pevny LH, Miller FD, Flores ERCell stem cellTAp63 prevents premature aging by promoting adult stem cell maintenance. Cell Stem Cell. 2009 Jul 02; 5(1):64-75.Cell Stem Cell2009-07-02T00:00:002009TAp63 prevents premature aging by promoting adult stem cell maintenance.23344544Su X, Chakravarti D, Flores ERNature reviews. Cancerp63 steps into the limelight: crucial roles in the suppression of tumorigenesis and metastasis. Nat Rev Cancer. 2013 02; 13(2):136-43.Nat Rev Cancer2013-02-01T00:00:002013p63 steps into the limelight: crucial roles in the suppression of tumorigenesis and metastasis.Authorship 2531151Authorship 253918719228734Lu J, Tan M, Huang WC, Li P, Guo H, Tseng LM, Su XH, Yang WT, Treekitkarnmongkol W, Andreeff M, Symmans F, Yu DClinical cancer research : an official journal of the American Association for Cancer ResearchMitotic deregulation by survivin in ErbB2-overexpressing breast cancer cells contributes to Taxol resistance. Clin Cancer Res. 2009 Feb 15; 15(4):1326-34.Clin Cancer Res2009-02-15T00:00:002009Mitotic deregulation by survivin in ErbB2-overexpressing breast cancer cells contributes to Taxol resistance.20157559Su X, Flores ERAgingTAp63: The fountain of youth. Aging (Albany NY). 2009 Oct 21; 1(10):866-9.Aging (Albany NY)2009-10-21T00:00:002009TAp63: The fountain of youth.Authorship 2653853Authorship 2669151Authorship 271415110713111Wakabayashi S, Pang T, Su X, Shigekawa MThe Journal of biological chemistryA novel topology model of the human Na(+)/H(+) exchanger isoform 1. J Biol Chem. 2000 Mar 17; 275(11):7942-9.J Biol Chem2000-03-17T00:00:002000A novel topology model of the human Na(+)/H(+) exchanger isoform 1.16478988Su X, Gopalakrishnan V, Stearns D, Aldape K, Lang FF, Fuller G, Snyder E, Eberhart CG, Majumder SMolecular and cellular biologyAbnormal expression of REST/NRSF and Myc in neural stem/progenitor cells causes cerebellar tumors by blocking neuronal differentiation. Mol Cell Biol. 2006 Mar; 26(5):1666-78.Mol Cell Biol2006-03-01T00:00:002006Abnormal expression of REST/NRSF and Myc in neural stem/progenitor cells causes cerebellar tumors by blocking neuronal differentiation.23040072Su X, Gi YJ, Chakravarti D, Chan IL, Zhang A, Xia X, Tsai KY, Flores ERCell metabolismTAp63 is a master transcriptional regulator of lipid and glucose metabolism. Cell Metab. 2012 Oct 03; 16(4):511-25.Cell Metab2012-10-03T00:00:002012TAp63 is a master transcriptional regulator of lipid and glucose metabolism.74Professor10Assistant Professor54Instructor47Distinguished Service ProfessorPEIJINGZHANGPEIJING ZHANG11826ZHANG, PEIJINGInstructor15767543Fuller GN, Su X, Price RE, Cohen ZR, Lang FF, Sawaya R, Majumder SMolecular cancer therapeuticsMany human medulloblastoma tumors overexpress repressor element-1 silencing transcription (REST)/neuron-restrictive silencer factor, which can be functionally countered by REST-VP16. Mol Cancer Ther. 2005 Mar; 4(3):343-9.Mol Cancer Ther2005-03-01T00:00:002005Many human medulloblastoma tumors overexpress repressor element-1 silencing transcription (REST)/neuron-restrictive silencer factor, which can be functionally countered by REST-VP16.20962848Su X, Chakravarti D, Cho MS, Liu L, Gi YJ, Lin YL, Leung ML, El-Naggar A, Creighton CJ, Suraokar MB, Wistuba I, Flores ERNatureTAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs. Nature. 2010 Oct 21; 467(7318):986-90.Nature2010-10-21T00:00:002010TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs.Authorship 847298Authorship 864661Authorship 867953Kidney InternationalStructure-function of the Na<sup>+</sup>/H<sup>+</sup> exchangers. Kidney International. 60:403-404.Structure-function of the Na<sup>+</sup>/H<sup>+</sup> exchangersOncotargetInhibiting glutaminase in acute myeloid leukemia. Oncotarget. 7:79722-79735.Inhibiting glutaminase in acute myeloid leukemiaMolecular and Cellular BiologyErratum. Molecular and Cellular Biology. 25:2872.Erratum29669287Zhang P, Xiao Z, Wang S, Zhang M, Wei Y, Hang Q, Kim J, Yao F, Rodriguez-Aguayo C, Ton BN, Lee M, Wang Y, Zhou Z, Zeng L, Hu X, Lawhon SE, Siverly AN, Su X, Li J, Xie X, Cheng X, Liu LC, Chang HW, Chiang SF, Lopez-Berestein G, Sood AK, Chen J, You MJ, Sun SC, Liang H, Huang Y, Yang X, Sun D, Sun Y, Hung MC, Ma LCell reportsZRANB1 Is an EZH2 Deubiquitinase and a Potential Therapeutic Target in Breast Cancer. Cell Rep. 2018 Apr 17; 23(3):823-837.Cell Rep2018-04-17T00:00:002018ZRANB1 Is an EZH2 Deubiquitinase and a Potential Therapeutic Target in Breast Cancer.Authorship 89013218D015534Chemicals & Drugs52315540.60959Trans-ActivatorsD010750Chemicals & Drugs51611540.647395PhosphoproteinsD014157Chemicals & Drugs126352660.358195Transcription FactorsD019588Disorders36380.973606Aging, PrematureAuthorship 90789214Authorship 9332221427806325Matre P, Velez J, Jacamo R, Qi Y, Su X, Cai T, Chan SM, Lodi A, Sweeney SR, Ma H, Davis RE, Baran N, Haferlach T, Su X, Flores ER, Gonzalez D, Konoplev S, Samudio I, DiNardo C, Majeti R, Schimmer AD, Li W, Wang T, Tiziani S, Konopleva MOncotargetInhibiting glutaminase in acute myeloid leukemia: metabolic dependency of selected AML subtypes. Oncotarget. 2016 Nov 29; 7(48):79722-79735.Oncotarget2016-11-29T00:00:002016Inhibiting glutaminase in acute myeloid leukemia: metabolic dependency of selected AML subtypes.29891922Yao F, Zhou Z, Kim J, Hang Q, Xiao Z, Ton BN, Chang L, Liu N, Zeng L, Wang W, Wang Y, Zhang P, Hu X, Su X, Liang H, Sun Y, Ma LNature communicationsSKP2- and OTUD1-regulated non-proteolytic ubiquitination of YAP promotes YAP nuclear localization and activity. Nat Commun. 2018 06 11; 9(1):2269.Nat Commun2018-06-11T00:00:002018SKP2- and OTUD1-regulated non-proteolytic ubiquitination of YAP promotes YAP nuclear localization and activity.D025521Chemicals & Drugs64718230.547934Tumor Suppressor ProteinsPathologyDepartment of MedicineDepartment of Molecular & Cellular BiologyMedicine-Hematology & OncologyMolecular & Cellular BiologyBaylor College of MedicineCHADCREIGHTONCHAD CREIGHTON0.000000000000000.000000000000001109CREIGHTON, CHADProfessorBERTO'MALLEYBERT O'MALLEY0.000000000000000.000000000000002464O'MALLEY, BERTDistinguished Service Professortrue1Distinguished Service ProfessorDistinguished Service Professortrue1ProfessorProfessor19494829Su X, Cho MS, Gi YJ, Ayanga BA, Sherr CJ, Flores ERThe EMBO journalRescue of key features of the p63-null epithelial phenotype by inactivation of Ink4a and Arf. EMBO J. 2009 Jul 08; 28(13):1904-15.EMBO J2009-06-04T00:00:002009Rescue of key features of the p63-null epithelial phenotype by inactivation of Ink4a and Arf.true1ProfessorProfessortrue1Assistant ProfessorAssistant Professortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1InstructorInstructortrue1ProfessorProfessor24449888Chakravarti D, Su X, Cho MS, Bui NH, Coarfa C, Venkatanarayan A, Benham AL, Flores Gonz?lez RE, Alana J, Xiao W, Leung ML, Vin H, Chan IL, Aquino A, M?ller N, Wang H, Cooney AJ, Parker-Thornburg J, Tsai KY, Gunaratne PH, Flores ERProceedings of the National Academy of Sciences of the United States of AmericaInduced multipotency in adult keratinocytes through down-regulation of ?Np63 or DGCR8. Proc Natl Acad Sci U S A. 2014 Feb 04; 111(5):E572-81.Proc Natl Acad Sci U S A2014-01-21T00:00:002014Induced multipotency in adult keratinocytes through down-regulation of ?Np63 or DGCR8.