JUANFUEYO-MARGARETOJUAN FUEYO-MARGARETO8674FUEYO-MARGARETO, JUANProfessorprns:coAuthorOfcoauthor ofFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressvivo:address1address line 1vivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provincevivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentDivisionvivo:hasResearchArearesearch areasvivo:hrJobTitleHR job titleInformation Resourcevivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:personInPositionpositionsPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPerson6767 Bertner StHouston77030-2603TXAuthorship 1636711Authorship 1652111Authorship 1658303Authorship 1658911Authorship 1665282Authorship 1672891Authorship 1683352Authorship 17206614Authorship 17377611Authorship 17405811Authorship 1743481Authorship 17453111Authorship 17556211Authorship 1763385Authorship 1771363Authorship 1780302Authorship 17849910Authorship 17850712Authorship 1789796Authorship 1794764Authorship 1795595Authorship 1804589Authorship 1809182Authorship 18104011Authorship 18168558Authorship 1834835Authorship 1842453Authorship 1856542Authorship 1864351Authorship 18968114Authorship 19380513Authorship 19598241338234Pou Serradell A, Fueyo J, Gomez C, Oliveras C, Espadaler JM, Alameda F, Graus FRevue neurologique[Paraneoplastic encephalomyelitis and Lambert-Eaton syndrome]. Rev Neurol (Paris). 1992; 148(10):605-9.Rev Neurol (Paris)1992-01-01T00:00:001992[Paraneoplastic encephalomyelitis and Lambert-Eaton syndrome].2046439G?mez Manzano C, Fueyo J, Pedro-Botet Montoya J, Fern?ndez-Sol? JMedicina clinica[Bezafibrate-induced necrotizing myopathy]. Med Clin (Barc). 1991 Mar 23; 96(11):439.Med Clin (Barc)1991-03-23T00:00:001991[Bezafibrate-induced necrotizing myopathy].3031778Fueyo Margareto J, Llach Vila J, Valderrama Labarca R, P?rez Ayuso RRevista espanola de las enfermedades del aparato digestivo[Bone metastases as the initial manifestation of hepatocarcinoma]. Rev Esp Enferm Apar Dig. 1986 Dec; 70(6):570-1.Rev Esp Enferm Apar Dig1986-12-01T00:00:001986[Bone metastases as the initial manifestation of hepatocarcinoma].8469424Graus F, Rowe G, Fueyo J, Darnell RB, Dalmau JNeuroscience lettersThe neuronal nuclear antigen recognized by the human anti-Ri autoantibody is expressed in central but not peripheral nervous system neurons. Neurosci Lett. 1993 Feb 19; 150(2):212-4.Neurosci Lett1993-02-19T00:00:001993The neuronal nuclear antigen recognized by the human anti-Ri autoantibody is expressed in central but not peripheral nervous system neurons.9230885Gomez-Manzano C, Fueyo J, Kyritsis AP, McDonnell TJ, Steck PA, Levin VA, Yung WKJournal of the National Cancer InstituteCharacterization of p53 and p21 functional interactions in glioma cells en route to apoptosis. J Natl Cancer Inst. 1997 Jul 16; 89(14):1036-44.J Natl Cancer Inst1997-07-16T00:00:001997Characterization of p53 and p21 functional interactions in glioma cells en route to apoptosis.9623977Fueyo J, Gomez-Manzano C, Yung WK, Liu TJ, Alemany R, McDonnell TJ, Shi X, Rao JS, Levin VA, Kyritsis APNature medicineOverexpression of E2F-1 in glioma triggers apoptosis and suppresses tumor growth in vitro and in vivo. Nat Med. 1998 Jun; 4(6):685-90.Nat Med1998-06-01T00:00:001998Overexpression of E2F-1 in glioma triggers apoptosis and suppresses tumor growth in vitro and in vivo.16037823Guo W, Zhu H, Zhang L, Davis J, Teraishi F, Roth JA, Stephens C, Fueyo J, Jiang H, Conrad C, Fang BCancer gene therapyCombination effect of oncolytic adenovirotherapy and TRAIL gene therapy in syngeneic murine breast cancer models. Cancer Gene Ther. 2006 Jan 01; 13(1):82-90.Cancer Gene Ther2006-01-01T00:00:002006Combination effect of oncolytic adenovirotherapy and TRAIL gene therapy in syngeneic murine breast cancer models.16207474Jiang H, Alemany R, Gomez-Manzano C, Medrano DR, Lemoine MG, Olson MV, Alonso MM, Lee OH, Conrad CC, Yung WK, Fueyo JNeoplasia (New York, N.Y.)Downmodulation of E1A protein expression as a novel strategy to design cancer-selective adenoviruses. Neoplasia. 2005 Aug; 7(8):723-9.Neoplasia2005-08-01T00:00:002005Downmodulation of E1A protein expression as a novel strategy to design cancer-selective adenoviruses.18006852Liu JL, Mao Z, LaFortune TA, Alonso MM, Gallick GE, Fueyo J, Yung WKCancer researchCell cycle-dependent nuclear export of phosphatase and tensin homologue tumor suppressor is regulated by the phosphoinositide-3-kinase signaling cascade. Cancer Res. 2007 Nov 15; 67(22):11054-63.Cancer Res2007-11-15T00:00:002007Cell cycle-dependent nuclear export of phosphatase and tensin homologue tumor suppressor is regulated by the phosphoinositide-3-kinase signaling cascade.18032923Jiang H, White EJ, Gomez-Manzano C, Fueyo JAutophagyAdenovirus's last trick: you say lysis, we say autophagy. Autophagy. 2008 Jan; 4(1):118-20.Autophagy2007-11-05T00:00:002007Adenovirus's last trick: you say lysis, we say autophagy.18089777Alonso MM, Gomez-Manzano C, Bekele BN, Yung WK, Fueyo JCancer researchAdenovirus-based strategies overcome temozolomide resistance by silencing the O6-methylguanine-DNA methyltransferase promoter. Cancer Res. 2007 Dec 15; 67(24):11499-504.Cancer Res2007-12-15T00:00:002007Adenovirus-based strategies overcome temozolomide resistance by silencing the O6-methylguanine-DNA methyltransferase promoter.20886384Gomez-Manzano C, Fueyo JCurrent opinion in molecular therapeuticsOncolytic adenoviruses for the treatment of brain tumors. Curr Opin Mol Ther. 2010 Oct; 12(5):530-7.Curr Opin Mol Ther2010-10-01T00:00:002010Oncolytic adenoviruses for the treatment of brain tumors.21059986Fueyo J, Gomez-Manzano C, Yung WKArchives of neurologyAdvances in translational research in neuro-oncology. Arch Neurol. 2011 Mar; 68(3):303-8.Arch Neurol2010-11-08T00:00:002010Advances in translational research in neuro-oncology.Neuro-OncologyMD AndersonFREDERICK FLANG JRFREDERICK F LANG JR8665LANG JR, FREDERICK FProfessorCANDELARIAGOMEZ-MANZANOCANDELARIA GOMEZ-MANZANO8676GOMEZ-MANZANO, CANDELARIAAssociate ProfessorHONGJIANGHONG JIANG8737JIANG, HONGAssociate ProfessorAMY BHEIMBERGERAMY B HEIMBERGER9035HEIMBERGER, AMY BProfessor5.013360.00481606456research areas5.489450.013114453coauthor of108.32515.088759similar to11124selected publicationsJOHN FREDERICKDE GROOTJOHN FREDERICK DE GROOT9019DE GROOT, JOHN FREDERICKProfessorAuthorship 2122701Authorship 2124451Authorship 2147911Authorship 2156442Authorship 2156861Authorship 2159011Authorship 2163071Authorship 2179881Authorship 2180418Authorship 2187513Authorship 2190111Authorship 2190388Authorship 2191364Authorship 2192458Authorship 2194703Authorship 2195312Authorship 2216204Authorship 2217862Authorship 2236005Authorship 2258995Authorship 2260713Authorship 22615311Authorship 2278036Authorship 231811122057016Fueyo J, Oliveras C, Pou A, Espadaler JMMovement disorders : official journal of the Movement Disorder SocietyProposal for a clinical definition of blepharokolysis. Mov Disord. 1991; 6(2):185-6.Mov Disord1991-01-01T00:00:001991Proposal for a clinical definition of blepharokolysis.2381250G?mez Manzano C, Fueyo J, Garc?s JM, Guti?rrez JMedicina clinica[Internuclear ophthalmoplegia related to opiate overdose]. Med Clin (Barc). 1990 Apr 28; 94(16):637.Med Clin (Barc)1990-04-28T00:00:001990[Internuclear ophthalmoplegia related to opiate overdose].8025201Garc?s JM, Fueyo J, Miralles R, Tous FAnales de medicina interna (Madrid, Spain : 1984)[Pelvic calcinosis. Its accidental diagnosis: multivisceral hydatidosis]. An Med Interna. 1994 Jan; 11(1):49.An Med Interna1994-01-01T00:00:001994[Pelvic calcinosis. Its accidental diagnosis: multivisceral hydatidosis].8121617Fueyo J, Ferrer I, Valldeoriola F, Graus FNeuroscience lettersThe expression of a neuronal nuclear antigen (Ri) recognized by the human anti-Ri autoantibody in the developing rat nervous system. Neurosci Lett. 1993 Nov 12; 162(1-2):141-4.Neurosci Lett1993-11-12T00:00:001993The expression of a neuronal nuclear antigen (Ri) recognized by the human anti-Ri autoantibody in the developing rat nervous system.8895506Fueyo J, Gomez-Manzano C, Bruner JM, Saito Y, Zhang B, Zhang W, Levin VA, Yung WK, Kyritsis APOncogeneHypermethylation of the CpG island of p16/CDKN2 correlates with gene inactivation in gliomas. Oncogene. 1996 Oct 17; 13(8):1615-9.Oncogene1996-10-17T00:00:001996Hypermethylation of the CpG island of p16/CDKN2 correlates with gene inactivation in gliomas.9864390Gomez-Manzano C, Fueyo J, Alameda F, Kyritsis AP, Yung WKInternational journal of molecular medicineGene therapy for gliomas: p53 and E2F-1 proteins and the target of apoptosis. Int J Mol Med. 1999 Jan; 3(1):81-5.Int J Mol Med1999-01-01T00:00:001999Gene therapy for gliomas: p53 and E2F-1 proteins and the target of apoptosis.10199333Fueyo J, Gomez-Manzano C, Yung WK, Kyritsis APArchives of neurologyTargeting in gene therapy for gliomas. Arch Neurol. 1999 Apr; 56(4):445-8.Arch Neurol1999-04-01T00:00:001999Targeting in gene therapy for gliomas.10644974Fueyo J, Gomez-Manzano C, Alemany R, Lee PS, McDonnell TJ, Mitlianga P, Shi YX, Levin VA, Yung WK, Kyritsis APOncogeneA mutant oncolytic adenovirus targeting the Rb pathway produces anti-glioma effect in vivo. Oncogene. 2000 Jan 06; 19(1):2-12.Oncogene2000-01-06T00:00:002000A mutant oncolytic adenovirus targeting the Rb pathway produces anti-glioma effect in vivo.11172602Mitlianga PG, Kyritsis AP, Gomez-Manzano C, Lemoine MG, Hu M, Liu TJ, Yung WK, Fueyo JInternational journal of oncologyCo-expression of E2F-2 enhances the p53 anti-cancer effect in human glioma cells. Int J Oncol. 2001 Feb; 18(2):343-7.Int J Oncol2001-02-01T00:00:002001Co-expression of E2F-2 enhances the p53 anti-cancer effect in human glioma cells.11407598Fueyo J, Gomez-Manzano C, Liu TJ, Yung WKJournal of neuro-oncologyDelivery of cell cycle genes to block astrocytoma growth. J Neurooncol. 2001 Feb; 51(3):277-87.J Neurooncol2001-02-01T00:00:002001Delivery of cell cycle genes to block astrocytoma growth.11445852Gomez-Manzano C, Lemoine MG, Hu M, He J, Mitlianga P, Liu TJ, Yung AW, Fueyo J, Groves MDInternational journal of oncologyAdenovirally-mediated transfer of E2F-1 potentiates chemosensitivity of human glioma cells to temozolomide and BCNU. Int J Oncol. 2001 Aug; 19(2):359-65.Int J Oncol2001-08-01T00:00:002001Adenovirally-mediated transfer of E2F-1 potentiates chemosensitivity of human glioma cells to temozolomide and BCNU.11559537Gomez-Manzano C, Mitlianga P, Fueyo J, Lee HY, Hu M, Spurgers KB, Glass TL, Koul D, Liu TJ, McDonnell TJ, Yung WKCancer researchTransfer of E2F-1 to human glioma cells results in transcriptional up-regulation of Bcl-2. Cancer Res. 2001 Sep 15; 61(18):6693-7.Cancer Res2001-09-15T00:00:002001Transfer of E2F-1 to human glioma cells results in transcriptional up-regulation of Bcl-2.11687897Calb? J, Marotta M, Cascall? M, Roig JM, Gelp? JL, Fueyo J, Mazo ACancer gene therapyAdenovirus-mediated wt-p16 reintroduction induces cell cycle arrest or apoptosis in pancreatic cancer. Cancer Gene Ther. 2001 Oct; 8(10):740-50.Cancer Gene Ther2001-10-01T00:00:002001Adenovirus-mediated wt-p16 reintroduction induces cell cycle arrest or apoptosis in pancreatic cancer.12370749Mitlianga PG, Gomez-Manzano C, Kyritsis AP, Fueyo JInternational journal of oncologyOverexpression of E2F-1 leads to bax-independent cell death in human glioma cells. Int J Oncol. 2002 Nov; 21(5):1015-20.Int J Oncol2002-11-01T00:00:002002Overexpression of E2F-1 leads to bax-independent cell death in human glioma cells.12384532Lamfers ML, Grill J, Dirven CM, Van Beusechem VW, Geoerger B, Van Den Berg J, Alemany R, Fueyo J, Curiel DT, Vassal G, Pinedo HM, Vandertop WP, Gerritsen WRCancer researchPotential of the conditionally replicative adenovirus Ad5-Delta24RGD in the treatment of malignant gliomas and its enhanced effect with radiotherapy. Cancer Res. 2002 Oct 15; 62(20):5736-42.Cancer Res2002-10-15T00:00:002002Potential of the conditionally replicative adenovirus Ad5-Delta24RGD in the treatment of malignant gliomas and its enhanced effect with radiotherapy.12509854Gomez-Manzano C, Fueyo J, Jiang H, Glass TL, Lee HY, Hu M, Liu JL, Jasti SL, Liu TJ, Conrad CA, Yung WKAnnals of neurologyMechanisms underlying PTEN regulation of vascular endothelial growth factor and angiogenesis. Ann Neurol. 2003 Jan; 53(1):109-17.Ann Neurol2003-01-01T00:00:002003Mechanisms underlying PTEN regulation of vascular endothelial growth factor and angiogenesis.15304571Gomez-Manzano C, Yung WK, Alemany R, Fueyo JNeurologyGenetically modified adenoviruses against gliomas: from bench to bedside. Neurology. 2004 Aug 10; 63(3):418-26.Neurology2004-08-10T00:00:002004Genetically modified adenoviruses against gliomas: from bench to bedside.16628012Alonso MM, Fueyo J, Yung WK, Gomez-Manzano CCell cycle (Georgetown, Tex.)E2F1 and telomerase: alliance in the dark side. Cell Cycle. 2006 May; 5(9):930-5.Cell Cycle2006-05-01T00:00:002006E2F1 and telomerase: alliance in the dark side.17134363Jiang H, Alonso MM, Gomez-Manzano C, Piao Y, Fueyo JExpert review of anticancer therapyOncolytic viruses and DNA-repair machinery: overcoming chemoresistance of gliomas. Expert Rev Anticancer Ther. 2006 Nov; 6(11):1585-92.Expert Rev Anticancer Ther2006-11-01T00:00:002006Oncolytic viruses and DNA-repair machinery: overcoming chemoresistance of gliomas.18246408Li JY, Wang H, May S, Song X, Fueyo J, Fuller GN, Wang HJournal of neuro-oncologyConstitutive activation of c-Jun N-terminal kinase correlates with histologic grade and EGFR expression in diffuse gliomas. J Neurooncol. 2008 May; 88(1):11-7.J Neurooncol2008-02-02T00:00:002008Constitutive activation of c-Jun N-terminal kinase correlates with histologic grade and EGFR expression in diffuse gliomas.18366015Martin V, Liu D, Fueyo J, Gomez-Manzano CHistology and histopathologyTie2: a journey from normal angiogenesis to cancer and beyond. Histol Histopathol. 2008 06; 23(6):773-80.Histol Histopathol2008-06-01T00:00:002008Tie2: a journey from normal angiogenesis to cancer and beyond.18927600Piao Y, Jiang H, Alemany R, Krasnykh V, Marini FC, Xu J, Alonso MM, Conrad CA, Aldape KD, Gomez-Manzano C, Fueyo JCancer gene therapyOncolytic adenovirus retargeted to Delta-EGFR induces selective antiglioma activity. Cancer Gene Ther. 2009 Mar; 16(3):256-65.Cancer Gene Ther2008-10-17T00:00:002008Oncolytic adenovirus retargeted to Delta-EGFR induces selective antiglioma activity.20484971Klionsky DJ, Codogno P, Cuervo AM, Deretic V, Elazar Z, Fueyo-Margareto J, Gewirtz DA, Kroemer G, Levine B, Mizushima N, Rubinsztein DC, Thumm M, Tooze SAAutophagyA comprehensive glossary of autophagy-related molecules and processes. Autophagy. 2010 May; 6(4):438-48.Autophagy2010-05-16T00:00:002010A comprehensive glossary of autophagy-related molecules and processes.21997368Klionsky DJ, Baehrecke EH, Brumell JH, Chu CT, Codogno P, Cuervo AM, Debnath J, Deretic V, Elazar Z, Eskelinen EL, Finkbeiner S, Fueyo-Margareto J, Gewirtz D, J??ttel? M, Kroemer G, Levine B, Melia TJ, Mizushima N, Rubinsztein DC, Simonsen A, Thorburn A, Thumm M, Tooze SAAutophagyA comprehensive glossary of autophagy-related molecules and processes (2nd edition). Autophagy. 2011 Nov; 7(11):1273-94.Autophagy2011-11-01T00:00:002011A comprehensive glossary of autophagy-related molecules and processes (2nd edition).Authorship 2362131Authorship 2396522Authorship 2402732Authorship 2405233Authorship 2419171Authorship 2427082Authorship 2431662Authorship 24808811Authorship 24829510Authorship 2484882Authorship 24975611Authorship 2511233Authorship 2512944Authorship 2535035Authorship 2542125Authorship 2544673Authorship 2567537Authorship 2576124Authorship 2577525Authorship 2615877Authorship 26221312087128G?mez Manzano C, Fueyo J, Miralles R, Guti?rrez JMedicina clinica[Wernicke's encephalopathy in a female patient with the acquired immunodeficiency syndrome]. Med Clin (Barc). 1990 Dec 01; 95(19):754-5.Med Clin (Barc)1990-12-01T00:00:001990[Wernicke's encephalopathy in a female patient with the acquired immunodeficiency syndrome].8380908Fueyo J, Gomez-Manzano C, Pascual J, Pou ANeurologyParaneoplastic syndromes. Neurology. 1993 Jan; 43(1):236.Neurology1993-01-01T00:00:001993Paraneoplastic syndromes.8630997Gomez-Manzano C, Fueyo J, Kyritsis AP, Steck PA, Roth JA, McDonnell TJ, Steck KD, Levin VA, Yung WKCancer researchAdenovirus-mediated transfer of the p53 gene produces rapid and generalized death of human glioma cells via apoptosis. Cancer Res. 1996 Feb 15; 56(4):694-9.Cancer Res1996-02-15T00:00:001996Adenovirus-mediated transfer of the p53 gene produces rapid and generalized death of human glioma cells via apoptosis.9592205Ke LD, Fueyo J, Chen X, Steck PA, Shi YX, Im SA, Yung WKInternational journal of oncologyA novel approach to glioma gene therapy: down-regulation of the vascular endothelial growth factor in glioma cells using ribozymes. Int J Oncol. 1998 Jun; 12(6):1391-6.Int J Oncol1998-06-01T00:00:001998A novel approach to glioma gene therapy: down-regulation of the vascular endothelial growth factor in glioma cells using ribozymes.9810797Fueyo J, G?mez-Manzano CNeurologia (Barcelona, Spain)[Molecular control of the cellular cycle and apoptosis: new treatments for gliomas]. Neurologia. 1998 Aug-Sep; 13(7):349-55.Neurologia1998-08-01T00:00:001998[Molecular control of the cellular cycle and apoptosis: new treatments for gliomas].10029081Im SA, Gomez-Manzano C, Fueyo J, Liu TJ, Ke LD, Kim JS, Lee HY, Steck PA, Kyritsis AP, Yung WKCancer researchAntiangiogenesis treatment for gliomas: transfer of antisense-vascular endothelial growth factor inhibits tumor growth in vivo. Cancer Res. 1999 Feb 15; 59(4):895-900.Cancer Res1999-02-15T00:00:001999Antiangiogenesis treatment for gliomas: transfer of antisense-vascular endothelial growth factor inhibits tumor growth in vivo.11205899Suzuki K, Fueyo J, Krasnykh V, Reynolds PN, Curiel DT, Alemany RClinical cancer research : an official journal of the American Association for Cancer ResearchA conditionally replicative adenovirus with enhanced infectivity shows improved oncolytic potency. Clin Cancer Res. 2001 Jan; 7(1):120-6.Clin Cancer Res2001-01-01T00:00:002001A conditionally replicative adenovirus with enhanced infectivity shows improved oncolytic potency.11333782Alemany R, G?mez-Manzano C, Fueyo JNeurologia (Barcelona, Spain)[Oncolytic adenovirus for the treatment of cerebral tumors: past, present and future]. Neurologia. 2001 Mar; 16(3):122-7.Neurologia2001-03-01T00:00:002001[Oncolytic adenovirus for the treatment of cerebral tumors: past, present and future].15720816Jiang H, Gomez-Manzano C, Alemany R, Medrano D, Alonso M, Bekele BN, Lin E, Conrad CC, Yung WK, Fueyo JNeoplasia (New York, N.Y.)Comparative effect of oncolytic adenoviruses with E1A-55 kDa or E1B-55 kDa deletions in malignant gliomas. Neoplasia. 2005 Jan; 7(1):48-56.Neoplasia2005-01-01T00:00:002005Comparative effect of oncolytic adenoviruses with E1A-55 kDa or E1B-55 kDa deletions in malignant gliomas.16264179Alonso MM, Fueyo J, Shay JW, Aldape KD, Jiang H, Lee OH, Johnson DG, Xu J, Kondo Y, Kanzawa T, Kyo S, Bekele BN, Zhou X, Nigro J, McDonald JM, Yung WK, Gomez-Manzano CJournal of the National Cancer InstituteExpression of transcription factor E2F1 and telomerase in glioblastomas: mechanistic linkage and prognostic significance. J Natl Cancer Inst. 2005 Nov 02; 97(21):1589-600.J Natl Cancer Inst2005-11-02T00:00:002005Expression of transcription factor E2F1 and telomerase in glioblastomas: mechanistic linkage and prognostic significance.17065226Jiang H, Olson MV, Medrano DR, Lee OH, Xu J, Piao Y, Alonso MM, Gomez-Manzano C, Hung MC, Yung WK, Fueyo JFASEB journal : official publication of the Federation of American Societies for Experimental BiologyA novel CRM1-dependent nuclear export signal in adenoviral E1A protein regulated by phosphorylation. FASEB J. 2006 Dec; 20(14):2603-5.FASEB J2006-10-25T00:00:002006A novel CRM1-dependent nuclear export signal in adenoviral E1A protein regulated by phosphorylation.17483310Olson MV, Johnson DG, Jiang H, Xu J, Alonso MM, Aldape KD, Fuller GN, Bekele BN, Yung WK, Gomez-Manzano C, Fueyo JCancer researchTransgenic E2F1 expression in the mouse brain induces a human-like bimodal pattern of tumors. Cancer Res. 2007 May 01; 67(9):4005-9.Cancer Res2007-05-01T00:00:002007Transgenic E2F1 expression in the mouse brain induces a human-like bimodal pattern of tumors.18708344Gomez-Manzano C, Holash J, Fueyo J, Xu J, Conrad CA, Aldape KD, de Groot JF, Bekele BN, Yung WKNeuro-oncologyVEGF Trap induces antiglioma effect at different stages of disease. Neuro Oncol. 2008 Dec; 10(6):940-5.Neuro Oncol2008-08-14T00:00:002008VEGF Trap induces antiglioma effect at different stages of disease.18756625Gomez-Manzano C, Alonso M, Jiang H, Fueyo JCancer biology & therapyInterspecies adenovirus fiber shows "evolutionary" advantage for oncolytic therapy of gliomas. Cancer Biol Ther. 2008 May; 7(5):794-6.Cancer Biol Ther2008-05-01T00:00:002008Interspecies adenovirus fiber shows "evolutionary" advantage for oncolytic therapy of gliomas.19216911Jiang H, White EJ, Conrad C, Gomez-Manzano C, Fueyo JMethods in enzymologyAutophagy pathways in glioblastoma. Methods Enzymol. 2009; 453:273-86.Methods Enzymol2009-01-01T00:00:002009Autophagy pathways in glioblastoma.19876078Dembinski JL, Spaeth EL, Fueyo J, Gomez-Manzano C, Studeny M, Andreeff M, Marini FCCancer gene therapyReduction of nontarget infection and systemic toxicity by targeted delivery of conditionally replicating viruses transported in mesenchymal stem cells. Cancer Gene Ther. 2010 Apr; 17(4):289-97.Cancer Gene Ther2009-10-30T00:00:002009Reduction of nontarget infection and systemic toxicity by targeted delivery of conditionally replicating viruses transported in mesenchymal stem cells.20935482Jiang H, Martin V, Alonso M, Gomez-Manzano C, Fueyo JAutophagyRB-E2F1: molecular rheostat for autophagy and apoptosis. Autophagy. 2010 Nov; 6(8):1216-7.Autophagy2010-11-16T00:00:002010RB-E2F1: molecular rheostat for autophagy and apoptosis.21948473Alonso MM, Jiang H, Gomez-Manzano C, Fueyo JMethods in molecular biology (Clifton, N.J.)Targeting brain tumor stem cells with oncolytic adenoviruses. Methods Mol Biol. 2012; 797:111-25.Methods Mol Biol2012-01-01T00:00:002012Targeting brain tumor stem cells with oncolytic adenoviruses.22230451Gomez-Manzano C, Jiang H, Alonso M, Yung WK, Fueyo JHandbook of clinical neurologyGene therapy. Handb Clin Neurol. 2012; 104:331-8.Handb Clin Neurol2012-01-01T00:00:002012Gene therapy.22242123Piya S, White EJ, Klein SR, Jiang H, McDonnell TJ, Gomez-Manzano C, Fueyo JPloS oneThe E1B19K oncoprotein complexes with Beclin 1 to regulate autophagy in adenovirus-infected cells. PLoS One. 2011; 6(12):e29467.PLoS One2011-12-29T00:00:002011The E1B19K oncoprotein complexes with Beclin 1 to regulate autophagy in adenovirus-infected cells.24809734Gabrusiewicz K, Liu D, Cortes-Santiago N, Hossain MB, Conrad CA, Aldape KD, Fuller GN, Marini FC, Alonso MM, Idoate MA, Gilbert MR, Fueyo J, Gomez-Manzano COncotargetAnti-vascular endothelial growth factor therapy-induced glioma invasion is associated with accumulation of Tie2-expressing monocytes. Oncotarget. 2014 Apr 30; 5(8):2208-20.Oncotarget2014-04-30T00:00:002014Anti-vascular endothelial growth factor therapy-induced glioma invasion is associated with accumulation of Tie2-expressing monocytes.Authorship 2632041Authorship 2637414Authorship 2642501Authorship 2646426Authorship 2652908Authorship 2656354Authorship 2660066Authorship 2678284Authorship 2678883Authorship 2680418Authorship 27006310Authorship 27038752236780Fueyo J, Garc?s JM, Soriano JC, Coll J, Rubi?s-Prat JRevista clinica espanola[Adenocarcinoma of the ovary in the ovarian remnant syndrome]. Rev Clin Esp. 1990 May; 186(8):415-6.Rev Clin Esp1990-05-01T00:00:001990[Adenocarcinoma of the ovary in the ovarian remnant syndrome].8351021Escudero D, Barnadas A, Codina M, Fueyo J, Graus FNeurologyAnti-Ri-associated paraneoplastic neurologic disorder without opsoclonus in a patient with breast cancer. Neurology. 1993 Aug; 43(8):1605-6.Neurology1993-08-01T00:00:001993Anti-Ri-associated paraneoplastic neurologic disorder without opsoclonus in a patient with breast cancer.8808318Fueyo J, Gomez-Manzano C, Yung WK, Zhang W, Lee PS, Majumder S, Perhouse M, Levin VA, Kyritsis APMolecular and cellular probesA frequent polymorphism in exon 1 of the p16/CDKN2 gene. Mol Cell Probes. 1995 Dec; 9(6):465-6.Mol Cell Probes1995-12-01T00:00:001995A frequent polymorphism in exon 1 of the p16/CDKN2 gene.10502394Alemany R, Gomez-Manzano C, Balagu? C, Yung WK, Curiel DT, Kyritsis AP, Fueyo JExperimental cell researchGene therapy for gliomas: molecular targets, adenoviral vectors, and oncolytic adenoviruses. 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Cancer Res. 2013 Apr 01; 73(7):2333-44.Cancer Res2013-01-30T00:00:002013TGF-? mediates homing of bone marrow-derived human mesenchymal stem cells to glioma stem cells.Authorship 843874Authorship 844537Authorship 846577Authorship 847682Authorship 848915Authorship 849392Authorship 849835Authorship 853687Authorship 856920Authorship 856993Authorship 857202Authorship 857387Authorship 857760Authorship 858426Authorship 860161Authorship 864278Authorship 866646Authorship 867654Future VirologyAdenovirus, autophagy and lysis. Future Virology. 6:1161-1164.Adenovirus, autophagy and lysisAutophagyErratum to. Autophagy. 12:443.Erratum toPLoS OneCritical role of autophagy in the processing of adenovirus capsid-incorporated cancer-specific antigens. PLoS One. 11.Critical role of autophagy in the processing of adenovirus capsid-incorporated cancer-specific antigensOncotargetSoluble Tie2 overrides the heightened invasion induced by anti-angiogenesis therapies in gliomas. 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Neoplasia. 2006 May; 8(5):419-28.Neoplasia2006-05-01T00:00:002006Sustained angiopoietin-2 expression disrupts vessel formation and inhibits glioma growth.Authorship 8876809Authorship 88827911D050130Procedures952780.77561Oncolytic VirotherapyMARTAALONSOMARTA ALONSO14337ALONSO, MARTAVisiting Assistant ProfessorD050504Living Beings761940.822384Oncolytic VirusesD001343Physiology3699360.612951AutophagyD000256Living Beings38514570.650367AdenoviridaeD005910Disorders38619630.434313GliomaNeurosurgeryDepartment of NeurosurgeryNeurosurgeryBaylor College of MedicineFREDERICKLANGFREDERICK LANG29.70706480000000-95.397162400000001037LANG, FREDERICKAdjunct Professortrue1Adjunct ProfessorAdjunct Professortrue1Visiting Assistant ProfessorVisiting Assistant Professortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1Associate ProfessorAssociate Professortrue1ProfessorProfessortrue1Associate ProfessorAssociate Professor24827739Jiang H, Clise-Dwyer K, Ruisaard KE, Fan X, Tian W, Gumin J, Lamfers ML, Kleijn A, Lang FF, Yung WK, Vence LM, Gomez-Manzano C, Fueyo JPloS oneDelta-24-RGD oncolytic adenovirus elicits anti-glioma immunity in an immunocompetent mouse model. 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