EUGENIE S KLEINERMAN to Animals
This is a "connection" page, showing publications EUGENIE S KLEINERMAN has written about Animals.
Connection Strength
1.149
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Circulating microRNAs and Cytokines as Prognostic Biomarkers for Doxorubicin-Induced Cardiac Injury and for Evaluating the Effectiveness of an Exercise Intervention. Clin Cancer Res. 2023 11 01; 29(21):4430-4440.
Score: 0.041
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Early skeletal muscle loss in adolescent and young adult cancer patients treated with anthracycline chemotherapy. Cancer Med. 2023 11; 12(22):20798-20809.
Score: 0.041
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Exercise intervention decreases acute and late doxorubicin-induced cardiotoxicity. Cancer Med. 2021 11; 10(21):7572-7584.
Score: 0.035
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Exosomal communication by metastatic osteosarcoma cells modulates alveolar macrophages to an M2 tumor-promoting phenotype and inhibits tumoricidal functions. Oncoimmunology. 2020; 9(1):1747677.
Score: 0.032
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The Fas/FasL Signaling Pathway: Its Role in the Metastatic Process and as a Target for Treating Osteosarcoma Lung Metastases. Adv Exp Med Biol. 2020; 1258:177-187.
Score: 0.031
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Anti-PD-1 therapy redirects macrophages from an M2 to an M1 phenotype inducing regression of OS lung metastases. Cancer Med. 2018 06; 7(6):2654-2664.
Score: 0.028
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miR-20a Regulates FAS Expression in Osteosarcoma Cells by Modulating FAS Promoter Activity and Can be Therapeutically Targeted to Inhibit Lung Metastases. Mol Cancer Ther. 2018 01; 17(1):130-139.
Score: 0.027
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Aerosol interleukin-2 induces natural killer cell proliferation in the lung and combination therapy improves the survival of mice with osteosarcoma lung metastasis. Pediatr Blood Cancer. 2014 Aug; 61(8):1362-8.
Score: 0.021
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EWS-FLI-1 regulates the neuronal repressor gene REST, which controls Ewing sarcoma growth and vascular morphology. Cancer. 2014 Feb 15; 120(4):579-88.
Score: 0.021
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Participation of the Fas/FasL signaling pathway and the lung microenvironment in the development of osteosarcoma lung metastases. Adv Exp Med Biol. 2014; 804:203-17.
Score: 0.021
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Blocking SDF-1a/CXCR4 downregulates PDGF-B and inhibits bone marrow-derived pericyte differentiation and tumor vascular expansion in Ewing tumors. Mol Cancer Ther. 2014 Feb; 13(2):483-91.
Score: 0.020
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Knockdown of autophagy-related protein 5, ATG5, decreases oxidative stress and has an opposing effect on camptothecin-induced cytotoxicity in osteosarcoma cells. BMC Cancer. 2013 Oct 26; 13:500.
Score: 0.020
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Natural killer cell therapy and aerosol interleukin-2 for the treatment of osteosarcoma lung metastasis. Pediatr Blood Cancer. 2014 Apr; 61(4):618-26.
Score: 0.020
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The histone deacetylase inhibitor, MS-275 (entinostat), downregulates c-FLIP, sensitizes osteosarcoma cells to FasL, and induces the regression of osteosarcoma lung metastases. Curr Cancer Drug Targets. 2013 May; 13(4):411-22.
Score: 0.020
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Inhibition of Cdc42-interacting protein 4 (CIP4) impairs osteosarcoma tumor progression. Curr Cancer Drug Targets. 2013 Jan; 13(1):48-56.
Score: 0.019
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Expression of c-FLIP in pulmonary metastases in osteosarcoma patients and human xenografts. Pediatr Blood Cancer. 2013 Apr; 60(4):575-9.
Score: 0.019
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miR-20a encoded by the miR-17-92 cluster increases the metastatic potential of osteosarcoma cells by regulating Fas expression. Cancer Res. 2012 Feb 15; 72(4):908-16.
Score: 0.018
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Genetically modified T cells targeting interleukin-11 receptor a-chain kill human osteosarcoma cells and induce the regression of established osteosarcoma lung metastases. Cancer Res. 2012 Jan 01; 72(1):271-81.
Score: 0.018
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SDF-1a induces PDGF-B expression and the differentiation of bone marrow cells into pericytes. Mol Cancer Res. 2011 Nov; 9(11):1462-70.
Score: 0.018
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CAPER-a alternative splicing regulates the expression of vascular endothelial growth factor165 in Ewing sarcoma cells. Cancer. 2012 Apr 15; 118(8):2106-16.
Score: 0.017
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Effect of the histone deacetylase inhibitor SNDX-275 on Fas signaling in osteosarcoma cells and the feasibility of its topical application for the treatment of osteosarcoma lung metastases. Cancer. 2011 Aug 01; 117(15):3457-67.
Score: 0.017
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Bone marrow cells participate in tumor vessel formation that supports the growth of Ewing's sarcoma in the lung. Angiogenesis. 2011 May; 14(2):125-33.
Score: 0.017
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Delta-like ligand 4-Notch signaling regulates bone marrow-derived pericyte/vascular smooth muscle cell formation. Blood. 2011 Jan 13; 117(2):719-26.
Score: 0.016
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Aerosol therapy for the treatment of osteosarcoma lung metastases: targeting the Fas/FasL pathway and rationale for the use of gemcitabine. J Aerosol Med Pulm Drug Deliv. 2010 Aug; 23(4):189-96.
Score: 0.016
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Vasculogenesis driven by bone marrow-derived cells is essential for growth of Ewing's sarcomas. Cancer Res. 2010 Feb 15; 70(4):1334-43.
Score: 0.016
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Delta-like ligand 4 plays a critical role in pericyte/vascular smooth muscle cell formation during vasculogenesis and tumor vessel expansion in Ewing's sarcoma. Clin Cancer Res. 2010 Feb 01; 16(3):848-56.
Score: 0.016
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Murine bone marrow-derived mesenchymal stem cells as vehicles for interleukin-12 gene delivery into Ewing sarcoma tumors. Cancer. 2009 Jan 01; 115(1):13-22.
Score: 0.015
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VEGF165 promotes the osteolytic bone destruction of ewing's sarcoma tumors by upregulating RANKL. Oncol Res. 2009; 18(2-3):117-25.
Score: 0.015
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The role of Fas/FasL in the metastatic potential of osteosarcoma and targeting this pathway for the treatment of osteosarcoma lung metastases. Cancer Treat Res. 2009; 152:497-508.
Score: 0.015
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Stromal cell-derived factor-1 stimulates vasculogenesis and enhances Ewing's sarcoma tumor growth in the absence of vascular endothelial growth factor. Int J Cancer. 2008 Aug 15; 123(4):831-7.
Score: 0.014
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Targeting Lyn inhibits tumor growth and metastasis in Ewing's sarcoma. Mol Cancer Ther. 2008 Jul; 7(7):1807-16.
Score: 0.014
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Bone marrow subsets differentiate into endothelial cells and pericytes contributing to Ewing's tumor vessels. Mol Cancer Res. 2008 Jun; 6(6):929-36.
Score: 0.014
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VEGF165 expression in the tumor microenvironment influences the differentiation of bone marrow-derived pericytes that contribute to the Ewing's sarcoma vasculature. Angiogenesis. 2008; 11(3):257-67.
Score: 0.014
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The osterix transcription factor down-regulates interleukin-1 alpha expression in mouse osteosarcoma cells. Mol Cancer Res. 2008 Jan; 6(1):119-26.
Score: 0.014
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VEGF165 is necessary to the metastatic potential of Fas(-) osteosarcoma cells but will not rescue the Fas(+) cells. J Exp Ther Oncol. 2008; 7(2):89-97.
Score: 0.014
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Intranasal granulocyte-macrophage colony-stimulating factor reduces the Aspergillus burden in an immunosuppressed murine model of pulmonary aspergillosis. Antimicrob Agents Chemother. 2008 Feb; 52(2):716-8.
Score: 0.013
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VEGF(165), but not VEGF(189), stimulates vasculogenesis and bone marrow cell migration into Ewing's sarcoma tumors in vivo. Mol Cancer Res. 2007 Nov; 5(11):1125-32.
Score: 0.013
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Fas-negative osteosarcoma tumor cells are selected during metastasis to the lungs: the role of the Fas pathway in the metastatic process of osteosarcoma. Mol Cancer Res. 2007 Oct; 5(10):991-9.
Score: 0.013
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Suppression of Ewing's sarcoma tumor growth, tumor vessel formation, and vasculogenesis following anti vascular endothelial growth factor receptor-2 therapy. Clin Cancer Res. 2007 Aug 15; 13(16):4867-73.
Score: 0.013
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Corruption of the Fas pathway delays the pulmonary clearance of murine osteosarcoma cells, enhances their metastatic potential, and reduces the effect of aerosol gemcitabine. Clin Cancer Res. 2007 Aug 01; 13(15 Pt 1):4503-10.
Score: 0.013
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Production of VEGF165 by Ewing's sarcoma cells induces vasculogenesis and the incorporation of CD34+ stem cells into the expanding tumor vasculature. Int J Cancer. 2006 Aug 15; 119(4):839-46.
Score: 0.012
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Intratumor murine interleukin-12 gene therapy suppressed the growth of local and distant Ewing's sarcoma. Cancer Gene Ther. 2006 Oct; 13(10):948-57.
Score: 0.012
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Intranasal interleukin-12 gene therapy enhanced the activity of ifosfamide against osteosarcoma lung metastases. Cancer. 2006 Mar 15; 106(6):1382-8.
Score: 0.012
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Interleukin-12 up-regulates Fas expression in human osteosarcoma and Ewing's sarcoma cells by enhancing its promoter activity. Mol Cancer Res. 2005 Dec; 3(12):685-91.
Score: 0.012
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Zoledronic acid inhibits primary bone tumor growth in Ewing sarcoma. Cancer. 2005 Oct 15; 104(8):1713-20.
Score: 0.012
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Aerosol gemcitabine inhibits the growth of primary osteosarcoma and osteosarcoma lung metastases. Int J Cancer. 2005 Sep 01; 116(3):458-63.
Score: 0.012
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A small interfering RNA targeting vascular endothelial growth factor inhibits Ewing's sarcoma growth in a xenograft mouse model. Clin Cancer Res. 2005 Apr 01; 11(7):2662-9.
Score: 0.011
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Osterix, a transcription factor for osteoblast differentiation, mediates antitumor activity in murine osteosarcoma. Cancer Res. 2005 Feb 15; 65(4):1124-8.
Score: 0.011
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Increased Fas expression reduces the metastatic potential of human osteosarcoma cells. Clin Cancer Res. 2004 Dec 01; 10(23):8114-9.
Score: 0.011
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Association of alphavbeta3 integrin expression with the metastatic potential and migratory and chemotactic ability of human osteosarcoma cells. Clin Exp Metastasis. 2004; 21(8):747-53.
Score: 0.010
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E1A gene therapy inhibits angiogenesis in a Ewing's sarcoma animal model. Mol Cancer Ther. 2003 Dec; 2(12):1313-9.
Score: 0.010
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Aerosol gene therapy with PEI: IL-12 eradicates osteosarcoma lung metastases. Clin Cancer Res. 2003 Aug 15; 9(9):3462-8.
Score: 0.010
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Eradication of osteosarcoma lung metastases following intranasal interleukin-12 gene therapy using a nonviral polyethylenimine vector. Cancer Gene Ther. 2002 Mar; 9(3):260-6.
Score: 0.009
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Eradication of osteosarcoma lung metastasis using intranasal gemcitabine. Anticancer Drugs. 2002 Feb; 13(2):155-61.
Score: 0.009
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Nucleus-mitochondria positive feedback loop formed by ERK5 S496 phosphorylation-mediated poly (ADP-ribose) polymerase activation provokes persistent pro-inflammatory senescent phenotype and accelerates coronary atherosclerosis after chemo-radiation. Redox Biol. 2021 11; 47:102132.
Score: 0.009
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Interleukin (IL)-12 and IL-12 gene transfer up-regulate Fas expression in human osteosarcoma and breast cancer cells. Cancer Res. 2001 May 15; 61(10):4066-71.
Score: 0.009
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Bempegaldesleukin (BEMPEG; NKTR-214) efficacy as a single agent and in combination with checkpoint-inhibitor therapy in mouse models of osteosarcoma. Int J Cancer. 2021 04 15; 148(8):1928-1937.
Score: 0.008
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[131I]MIBG exports via MRP transporters and inhibition of the MRP transporters improves accumulation of [131I]MIBG in neuroblastoma. Nucl Med Biol. 2020 Nov - Dec; 90-91:49-54.
Score: 0.008
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Intranasal therapy with an adenoviral vector containing the murine interleukin-12 gene eradicates osteosarcoma lung metastases. Clin Cancer Res. 2000 Sep; 6(9):3713-8.
Score: 0.008
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Vaccine efficacy against primary and metastatic cancer with in vitro-generated CD103+ conventional dendritic cells. J Immunother Cancer. 2020 04; 8(1).
Score: 0.008
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Vascular modulation through exercise improves chemotherapy efficacy in Ewing sarcoma. Pediatr Blood Cancer. 2019 09; 66(9):e27835.
Score: 0.007
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A nude mouse model of human osteosarcoma lung metastases for evaluating new therapeutic strategies. Clin Exp Metastasis. 1999; 17(6):501-6.
Score: 0.007
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Aerobic Exercise During Early Murine Doxorubicin Exposure Mitigates Cardiac Toxicity. J Pediatr Hematol Oncol. 2018 04; 40(3):208-215.
Score: 0.007
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Diet and exercise interventions for pediatric cancer patients during therapy: tipping the scales for better outcomes. Pediatr Res. 2018 01; 83(1-1):50-56.
Score: 0.007
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BMTP-11 is active in preclinical models of human osteosarcoma and a candidate targeted drug for clinical translation. Proc Natl Acad Sci U S A. 2017 07 25; 114(30):8065-8070.
Score: 0.007
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Induction of NKG2D Ligands on Solid Tumors Requires Tumor-Specific CD8+ T Cells and Histone Acetyltransferases. Cancer Immunol Res. 2017 04; 5(4):300-311.
Score: 0.006
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Hes4: A potential prognostic biomarker for newly diagnosed patients with high-grade osteosarcoma. Pediatr Blood Cancer. 2017 05; 64(5).
Score: 0.006
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Transfection of human topoisomerase II alpha into etoposide-resistant cells: transient increase in sensitivity followed by down-regulation of the endogenous gene. Biochem J. 1996 Oct 01; 319 ( Pt 1):307-13.
Score: 0.006
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Effect of transfection of a Drosophila topoisomerase II gene into a human brain tumour cell line intrinsically resistant to etoposide. Br J Cancer. 1996 Jun; 73(11):1373-80.
Score: 0.006
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Lack of Immunomodulatory Interleukin-27 Enhances Oncogenic Properties of Mutant p53 In Vivo. Clin Cancer Res. 2016 08 01; 22(15):3876-83.
Score: 0.006
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Transfection of a human topoisomerase II alpha gene into etoposide-resistant human breast tumor cells sensitizes the cells to etoposide. Oncol Res. 1996; 8(3):101-10.
Score: 0.006
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Liposomal MTP-PE: a promising new biologic response modifier. Oncol Nurs Forum. 1995 Jun; 22(5):809-16.
Score: 0.006
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Toward a drug development path that targets metastatic progression in osteosarcoma. Clin Cancer Res. 2014 Aug 15; 20(16):4200-9.
Score: 0.005
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CD8+T cell-specific induction of NKG2D receptor by doxorubicin plus interleukin-12 and its contribution to CD8+T cell accumulation in tumors. Mol Cancer. 2014 Feb 24; 13:34.
Score: 0.005
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The narrow-spectrum HDAC inhibitor entinostat enhances NKG2D expression without NK cell toxicity, leading to enhanced recognition of cancer cells. Pharm Res. 2015 Mar; 32(3):779-92.
Score: 0.005
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Therapy of cancer metastasis by systemic activation of macrophages: from the bench to the clinic. Res Immunol. 1993 May; 144(4):284-7; discussion 294-8.
Score: 0.005
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Liposome-encapsulated muramyl tripeptide: a new biologic response modifier for the treatment of osteosarcoma. Cancer Treat Res. 1993; 62:101-7.
Score: 0.005
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Muramyl tripeptide phosphatidylethanolamine encapsulated in liposomes stimulates monocyte production of tumor necrosis factor and interleukin-1 in vitro. Cancer Commun. 1991; 3(10-11):313-21.
Score: 0.004
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Platelet-derived growth factor receptor beta inhibition increases tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) sensitivity: imatinib and TRAIL dual therapy. Cancer. 2010 Aug 15; 116(16):3892-902.
Score: 0.004
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Aerosol gemcitabine: preclinical safety and in vivo antitumor activity in osteosarcoma-bearing dogs. J Aerosol Med Pulm Drug Deliv. 2010 Aug; 23(4):197-206.
Score: 0.004
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Differential release of TNF-alpha, IL 1, and PGE2 by human blood monocytes subsequent to interaction with different bacterial derived agents. Lymphokine Res. 1990; 9(4):449-63.
Score: 0.004
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Liposomal MTP-PE for the adjuvant therapy of osteosarcoma. Prog Clin Biol Res. 1990; 343:263-79.
Score: 0.004
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Antagonism of chemokine receptor CXCR3 inhibits osteosarcoma metastasis to lungs. Int J Cancer. 2009 Dec 01; 125(11):2586-94.
Score: 0.004
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Inhibiting platelet-derived growth factor beta reduces Ewing's sarcoma growth and metastasis in a novel orthotopic human xenograft model. In Vivo. 2009 Nov-Dec; 23(6):903-9.
Score: 0.004
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Immunotherapy for osteosarcoma: genetic modification of T cells overcomes low levels of tumor antigen expression. Mol Ther. 2009 Oct; 17(10):1779-87.
Score: 0.004
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Synthetic peptide corresponding to a conserved domain of the retroviral protein p15E blocks IL-1-mediated signal transduction. J Immunol. 1989 Jun 15; 142(12):4321-8.
Score: 0.004
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Activated human blood monocytes trigger the antitumor activity of blood polymorphonuclear cells. Lymphokine Res. 1989; 8(4):427-37.
Score: 0.004
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The endogenous anti-angiogenic VEGF isoform, VEGF165b inhibits human tumour growth in mice. Br J Cancer. 2008 Apr 08; 98(7):1250-7.
Score: 0.003
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Intravenous administration of the conditionally replicative adenovirus Ad5-Delta24RGD induces regression of osteosarcoma lung metastases. Mol Cancer. 2008 Jan 23; 7:9.
Score: 0.003
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EWS/FLI1 regulates tumor angiogenesis in Ewing's sarcoma via suppression of thrombospondins. Cancer Res. 2007 Jul 15; 67(14):6675-84.
Score: 0.003
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Intracellular activation of human and rodent macrophages by human lymphokines encapsulated in liposomes. J Leukoc Biol. 1985 May; 37(5):571-84.
Score: 0.003
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Adenovirus-mediated human topoisomerase IIalpha gene transfer increases the sensitivity of etoposide-resistant human and mouse breast cancer cells. Acta Oncol. 2005; 44(3):240-7.
Score: 0.003
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9-Nitrocamptothecin liposome aerosol treatment of melanoma and osteosarcoma lung metastases in mice. Clin Cancer Res. 2000 Jul; 6(7):2876-80.
Score: 0.002
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Anti-cancer activity of 9-nitrocamptothecin liposome aerosol in mice. Trans Am Clin Climatol Assoc. 2000; 111:135-45.
Score: 0.002
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Mechanisms of Kupffer cell cytotoxicity in vitro against the syngeneic murine colon adenocarcinoma line MCA26. J Leukoc Biol. 1993 Jun; 53(6):715-21.
Score: 0.001
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Sequential therapy with chemotherapeutic drugs and liposome-encapsulated muramyl tripeptide: determination of potential interactions between these agents. Oncol Res. 1992; 4(10):413-8.
Score: 0.001
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Inhibition of protein kinase C by a peptide conjugate homologous to a domain of the retroviral protein p15E. J Immunol. 1990 Oct 15; 145(8):2566-70.
Score: 0.001
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Macrophages and cancer. Cancer Metastasis Rev. 1990 Feb; 8(4):319-51.
Score: 0.001
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Human recombinant macrophage colony stimulating factor activates murine Kupffer cells to a cytotoxic state. Lymphokine Res. 1990; 9(3):355-63.
Score: 0.001
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B-cell line-derived interleukin 1 is cytotoxic for melanoma cells and promotes the proliferation of an astrocytoma cell line. Lymphokine Res. 1987; 6(2):83-91.
Score: 0.001
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Abrogation of species specificity for activation of tumoricidal properties in macrophages by recombinant mouse or human interferon-gamma encapsulated in liposomes. J Immunol. 1985 Dec; 135(6):4289-96.
Score: 0.001