Connection

WILLIAM K PLUNKETT JR to Drug Synergism

This is a "connection" page, showing publications WILLIAM K PLUNKETT JR has written about Drug Synergism.
Connection Strength

0.557
  1. Killing of chronic lymphocytic leukemia by the combination of fludarabine and oxaliplatin is dependent on the activity of XPF endonuclease. Clin Cancer Res. 2011 Jul 15; 17(14):4731-41.
    View in: PubMed
    Score: 0.074
  2. Homoharringtonine reduced Mcl-1 expression and induced apoptosis in chronic lymphocytic leukemia. Blood. 2011 Jan 06; 117(1):156-64.
    View in: PubMed
    Score: 0.071
  3. A sequential blockade strategy for the design of combination therapies to overcome oncogene addiction in chronic myelogenous leukemia. Cancer Res. 2006 Nov 15; 66(22):10959-66.
    View in: PubMed
    Score: 0.054
  4. Fludarabine increases oxaliplatin cytotoxicity in normal and chronic lymphocytic leukemia lymphocytes by suppressing interstrand DNA crosslink removal. Blood. 2006 Dec 15; 108(13):4187-93.
    View in: PubMed
    Score: 0.053
  5. Targeting Hsp90 by 17-AAG in leukemia cells: mechanisms for synergistic and antagonistic drug combinations with arsenic trioxide and Ara-C. Leukemia. 2006 Apr; 20(4):610-9.
    View in: PubMed
    Score: 0.052
  6. S-Phase arrest by nucleoside analogues and abrogation of survival without cell cycle progression by 7-hydroxystaurosporine. Cancer Res. 2001 Feb 01; 61(3):1065-72.
    View in: PubMed
    Score: 0.036
  7. Expression of ERCC1 antisense RNA abrogates gemicitabine-mediated cytotoxic synergism with cisplatin in human colon tumor cells defective in mismatch repair but proficient in nucleotide excision repair. Clin Cancer Res. 2000 Mar; 6(3):773-81.
    View in: PubMed
    Score: 0.034
  8. Gemcitabine: metabolism, mechanisms of action, and self-potentiation. Semin Oncol. 1995 Aug; 22(4 Suppl 11):3-10.
    View in: PubMed
    Score: 0.025
  9. Arabinosyl-2-fluoroadenine augments cisplatin cytotoxicity and inhibits cisplatin-DNA cross-link repair. Mol Pharmacol. 1995 May; 47(5):1072-9.
    View in: PubMed
    Score: 0.024
  10. Combination of fludarabine and arabinosylcytosine for treatment of chronic lymphocytic leukemia: clinical efficacy and modulation of arabinosylcytosine pharmacology. Cancer Chemother Pharmacol. 1994; 34(1):30-6.
    View in: PubMed
    Score: 0.022
  11. Fludarabine potentiates metabolism of cytarabine in patients with acute myelogenous leukemia during therapy. J Clin Oncol. 1993 Jan; 11(1):116-24.
    View in: PubMed
    Score: 0.021
  12. Fludarabine infusion potentiates arabinosylcytosine metabolism in lymphocytes of patients with chronic lymphocytic leukemia. Cancer Res. 1992 Feb 15; 52(4):897-903.
    View in: PubMed
    Score: 0.019
  13. Cell cycle-specific metabolism of arabinosyl nucleosides in K562 human leukemia cells. Cancer Chemother Pharmacol. 1992; 31(1):11-7.
    View in: PubMed
    Score: 0.019
  14. Mitoxantrone-induced DNA damage in leukemia cells is enhanced by treatment with high-dose arabinosylcytosine. Cancer Chemother Pharmacol. 1988; 22(3):205-10.
    View in: PubMed
    Score: 0.015
  15. Mdm2 inhibitor Nutlin-3a induces p53-mediated apoptosis by transcription-dependent and transcription-independent mechanisms and may overcome Atm-mediated resistance to fludarabine in chronic lymphocytic leukemia. Blood. 2006 Aug 01; 108(3):993-1000.
    View in: PubMed
    Score: 0.013
  16. Inhibition of adenosine deaminase to increase the antitumor activity of adenine nucleoside analogues. Ann N Y Acad Sci. 1985; 451:150-9.
    View in: PubMed
    Score: 0.012
  17. Increased toxicity of 9-beta-D-arabinofuranosyladenine in the presence of an inhibitor of adenosine deaminase. Ann N Y Acad Sci. 1977 Mar 04; 284:91-102.
    View in: PubMed
    Score: 0.007
  18. Two approaches that increase the activity of analogs of adenine nucleosides in animal cells. Cancer Res. 1975 Jun; 35(6):1547-54.
    View in: PubMed
    Score: 0.006
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.