EDWIN JUSTIN OSTRIN

TitleAssistant Professor
InstitutionMD Anderson
DepartmentGeneral Internal Medicine
Address1515 Holcombe Blvd.
Houston TX 77030
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Irajizad E, Fahrmann JF, Toumazis I, Vykoukal J, Dennison JB, Shen Y, Do KA, Ostrin EJ, Feng Z, Hanash S. Biomarker trajectory for earlier detection of lung cancer. EBioMedicine. 2024 Oct; 108:105377. PMID: 39353277; PMCID: PMC11472629.
      Citations:    Fields:    Translation:Humans
    2. Moghaddam SJ, Document S, Savai R, Salehi-Rad R, Sengupta S, Kammer MN, Massion P, Beane JE, Ostrin EJ, Priolo C, Tennis MA, Stabile LP, Bauer AK, Sears CR, Szabo E, Rivera MP, Powell CA, Kadara H, Jenkins BJ, Dubinett SM, Houghton AM, Kim CF, Keith RL, Moghaddam SJ, Jenkins BJ, Moghaddam SJ, Savai R, Salehi-Rad R, Sengupta S, Kammer MN, Massion P, Beane JE, Ostrin EJ, Priolo C, Tennis MA, Stabile LP, Bauer AK, Sears CR, Szabo E, Rivera MP, Powell CA, Kadara H, Jenkins BJ, Dubinett SM, Houghton AM, Kim CF, Keith RL. Premalignant Progression in the Lung: Knowledge Gaps and Novel Opportunities for Interception of Non-Small Cell Lung Cancer. An Official American Thoracic Society Research Statement. Am J Respir Crit Care Med. 2024 Sep 01; 210(5):548-571. PMID: 39115548; PMCID: PMC11389570.
      Citations:    Fields:    Translation:Humans
    3. Pan K, Owens J, Elamin Y, Lu C, Routbort M, Zhang J, Fossella F, Negrao MV, Altan M, Pozadzides J, Skoulidis F, Tsao A, Cascone T, Heymach JV, Ostrin E, Le X, Pan K, Owens J, Elamin Y, Lu C, Routbort M, Zhang J, Fossella F, Negrao MV, Altan M, Pozadzides J, Skoulidis F, Tsao A, Cascone T, Heymach JV, Ostrin E, Le X. Mutational Characteristics and Clinical Outcomes for Lung Adenocarcinoma With EGFR Germline Mutations. J Thorac Oncol. 2024 Oct; 19(10):1438-1448. PMID: 38866326.
      Citations: 1     Fields:    Translation:Humans
    4. Song L, Irajizad E, Rundle A, Sesso HD, Gaziano JM, Vykoukal JV, Do KA, Dennison JB, Ostrin EJ, Fahrmann JF, Perera F, Hanash S. Validation of a Blood-Based Protein Biomarker Panel for a Risk Assessment of Lethal Lung Cancer in the Physicians' Health Study. Cancers (Basel). 2024 May 30; 16(11). PMID: 38893188; PMCID: PMC11171146.
      Citations:    
    5. Hu X, Zhu B, Vokes N, Fujimoto J, Rojas Alvarez FR, Heeke S, Moreira AL, Solis LM, Haymaker C, Velcheti V, Sterman DH, Pass HI, Cheng C, Lee JJ, Zhang J, Wei Z, Wu J, Le X, Ostrin E, Toumazis I, Gibbons D, Su D, Fukuoka J, Antonoff MB, Gerber DE, Li C, Kadara H, Wang L, Davis M, Heymach JV, Hannash S, Wistuba I, Dubinett S, Alexandrov L, Lippman S, Spira A, Futreal AP, Reuben A, Zhang J. The evolution of lung adenocarcinoma precursors is associated with chromosomal instability and transition from innate to adaptive immune response/evasion. Res Sq. 2024 May 15. PMID: 38798564; PMCID: PMC11118701.
      Citations:    
    6. Salehjahromi M, Karpinets TV, Sujit SJ, Qayati M, Chen P, Aminu M, Saad MB, Bandyopadhyay R, Hong L, Sheshadri A, Lin J, Antonoff MB, Sepesi B, Ostrin EJ, Toumazis I, Huang P, Cheng C, Cascone T, Vokes NI, Behrens C, Siewerdsen JH, Hazle JD, Chang JY, Zhang J, Lu Y, Godoy MCB, Chung C, Jaffray D, Wistuba I, Lee JJ, Vaporciyan AA, Gibbons DL, Gladish G, Heymach JV, Wu CC, Zhang J, Wu J. Synthetic PET from CT improves diagnosis and prognosis for lung cancer: Proof of concept. Cell Rep Med. 2024 Mar 19; 5(3):101463. PMID: 38471502; PMCID: PMC10983039.
      Citations: 2     Fields:    Translation:Humans
    7. Nofal S, Niu J, Resong P, Jin J, Merriman KW, Le X, Katki H, Heymach J, Antonoff MB, Ostrin E, Wu J, Zhang J, Toumazis I. Personal history of cancer as a risk factor for second primary lung cancer: Implications for lung cancer screening. Cancer Med. 2024 Mar; 13(5):e7069. PMID: 38466021; PMCID: PMC10926882.
      Citations: 2     Fields:    Translation:Humans
    8. Tai MC, Bantis LE, Parhy G, Kato T, Tanaka I, Chow CW, Fujimoto J, Behrens C, Hase T, Kawaguchi K, Fahrmann JF, Ostrin EJ, Yokoi K, Chen-Yoshikawa TF, Hasegawa Y, Hanash SM, Wistuba II, Taguchi A. Circulating microRNA Panel for Prediction of Recurrence and Survival in Early-Stage Lung Adenocarcinoma. Int J Mol Sci. 2024 Feb 16; 25(4). PMID: 38397007; PMCID: PMC10888571.
      Citations: 1     Fields:    Translation:Humans
    9. Le?n-Letelier RA, Dou R, Vykoukal J, Sater AHA, Ostrin E, Hanash S, Fahrmann JF. The kynurenine pathway presents multi-faceted metabolic vulnerabilities in cancer. Front Oncol. 2023; 13:1256769. PMID: 37876966; PMCID: PMC10591110.
      Citations:    
    10. Irajizad E, Fahrmann JF, Marsh T, Vykoukal J, Dennison JB, Long JP, Do KA, Feng Z, Hanash S, Ostrin EJ. Mortality Benefit of a Blood-Based Biomarker Panel for Lung Cancer on the Basis of the Prostate, Lung, Colorectal, and Ovarian Cohort. J Clin Oncol. 2023 09 20; 41(27):4360-4368. PMID: 37379494; PMCID: PMC10522105.
      Citations: 4     Fields:    Translation:Humans
    11. Ostrin EJ, Rider NL, Alousi AM, Irajizad E, Li L, Peng Q, Kim ST, Bashoura L, Arain MH, Noor LZ, Patel N, Mehta R, Popat UR, Hosing C, Jenq RR, Rondon G, Hanash SM, Paczesny S, Shpall EJ, Champlin RE, Dickey BF, Sheshadri A. A Nasal Inflammatory Cytokine Signature Is Associated with Early Graft-versus-Host Disease of the Lung after Allogeneic Hematopoietic Cell Transplantation: Proof of Concept. Immunohorizons. 2023 Jun 01; 7(6):421-430. PMID: 37289498; PMCID: PMC10491477.
      Citations:    Fields:    Translation:Humans
    12. Deboever N, Ostrin EJ, Antonoff MB. Liquid Biopsy as an Adjunct to Lung Screening Imaging. Thorac Surg Clin. 2023 Nov; 33(4):411-419. PMID: 37806743.
      Citations: 1     Fields:    Translation:HumansPHPublic Health
    13. Le?n-Letelier RA, Abdel Sater AH, Chen Y, Park S, Wu R, Irajizad E, Dennison JB, Katayama H, Vykoukal JV, Hanash S, Ostrin EJ, Fahrmann JF. Kynureninase Upregulation Is a Prominent Feature of NFR2-Activated Cancers and Is Associated with Tumor Immunosuppression and Poor Prognosis. Cancers (Basel). 2023 Jan 29; 15(3). PMID: 36765792; PMCID: PMC9913753.
      Citations: 1     
    14. Vykoukal J, Fahrmann JF, Patel N, Shimizu M, Ostrin EJ, Dennison JB, Ivan C, Goodman GE, Thornquist MD, Barnett MJ, Feng Z, Calin GA, Hanash SM. Contributions of Circulating microRNAs for Early Detection of Lung Cancer. Cancers (Basel). 2022 Aug 30; 14(17). PMID: 36077759; PMCID: PMC9454665.
      Citations:    
    15. Irajizad E, Fahrmann JF, Long JP, Vykoukal J, Kobayashi M, Capello M, Yu CY, Cai Y, Hsiao FC, Patel N, Park S, Peng Q, Dennison JB, Kato T, Tai MC, Taguchi A, Kadara H, Wistuba II, Katayama H, Do KA, Hanash SM, Ostrin EJ. A Comprehensive Search of Non-Canonical Proteins in Non-Small Cell Lung Cancer and Their Impact on the Immune Response. Int J Mol Sci. 2022 Aug 11; 23(16). PMID: 36012199; PMCID: PMC9409146.
      Citations:    
    16. Yuan B, Clowers MJ, Velasco WV, Peng S, Peng Q, Shi Y, Ramos-Castaneda M, Zarghooni M, Yang S, Babcock RL, Chang SH, Heymach JV, Zhang J, Ostrin EJ, Watowich SS, Kadara H, Moghaddam SJ. Targeting IL-1? as an immunopreventive and therapeutic modality for K-ras-mutant lung cancer. JCI Insight. 2022 06 08; 7(11). PMID: 35471938; PMCID: PMC9220853.
      Citations:    Fields:    Translation:HumansAnimalsCells
    17. Fahrmann JF, Tanaka I, Irajizad E, Mao X, Dennison JB, Murage E, Casabar J, Mayo J, Peng Q, Celiktas M, Vykoukal JV, Park S, Taguchi A, Delgado O, Tripathi SC, Katayama H, Soto LMS, Rodriguez-Canales J, Behrens C, Wistuba I, Hanash S, Ostrin EJ. Mutational Activation of the NRF2 Pathway Upregulates Kynureninase Resulting in Tumor Immunosuppression and Poor Outcome in Lung Adenocarcinoma. Cancers (Basel). 2022 May 21; 14(10). PMID: 35626147; PMCID: PMC9139317.
      Citations:    
    18. Tanaka I, Dayde D, Tai MC, Mori H, Solis LM, Tripathi SC, Fahrmann JF, Unver N, Parhy G, Jain R, Parra ER, Murakami Y, Aguilar-Bonavides C, Mino B, Celiktas M, Dhillon D, Casabar JP, Nakatochi M, Stingo F, Baladandayuthapani V, Wang H, Katayama H, Dennison JB, Lorenzi PL, Do KA, Fujimoto J, Behrens C, Ostrin EJ, Rodriguez-Canales J, Hase T, Fukui T, Kajino T, Kato S, Yatabe Y, Hosoda W, Kawaguchi K, Yokoi K, Chen-Yoshikawa TF, Hasegawa Y, Gazdar AF, Wistuba II, Hanash S, Taguchi A. SRGN-Triggered Aggressive and Immunosuppressive Phenotype in a Subset of TTF-1-Negative Lung Adenocarcinomas. J Natl Cancer Inst. 2022 02 07; 114(2):290-301. PMID: 34524427; PMCID: PMC8826620.
      Citations: 2     Fields:    Translation:HumansAnimals
    19. Fahrmann JF, Marsh T, Irajizad E, Patel N, Murage E, Vykoukal J, Dennison JB, Do KA, Ostrin E, Spitz MR, Lam S, Shete S, Meza R, Feng Z, Hanash SM, Tammem?gi MC. Blood-Based Biomarker Panel for Personalized Lung Cancer Risk Assessment. J Clin Oncol. 2022 03 10; 40(8):876-883. PMID: 34995129; PMCID: PMC8906454.
      Citations: 3     Fields:    Translation:HumansPHPublic Health
    20. Tripathi SC, Vedpathak D, Ostrin EJ. The Functional and Mechanistic Roles of Immunoproteasome Subunits in Cancer. Cells. 2021 12 20; 10(12). PMID: 34944095; PMCID: PMC8700164.
      Citations: 1     Fields:    Translation:HumansAnimals
    21. Fahrmann JF, Katayama H, Irajizad E, Chakraborty A, Kato T, Mao X, Park S, Murage E, Rusling L, Yu CY, Cai Y, Hsiao FC, Dennison JB, Tran H, Ostrin E, Wilson DO, Yuan JM, Vykoukal J, Hanash S. Plasma Based Protein Signatures Associated with Small Cell Lung Cancer. Cancers (Basel). 2021 Aug 06; 13(16). PMID: 34439128; PMCID: PMC8391533.
      Citations: 1     
    22. Hu X, Fujimoto J, Ying L, Fukuoka J, Ashizawa K, Sun W, Reuben A, Chow CW, McGranahan N, Chen R, Hu J, Godoy MC, Tabata K, Kuroda K, Shi L, Li J, Behrens C, Parra ER, Little LD, Gumbs C, Mao X, Song X, Tippen S, Thornton RL, Kadara H, Scheet P, Roarty E, Ostrin EJ, Wang X, Carter BW, Antonoff MB, Zhang J, Vaporciyan AA, Pass H, Swisher SG, Heymach JV, Lee JJ, Wistuba II, Hong WK, Futreal PA, Su D, Zhang J. Author Correction: Multi-region exome sequencing reveals genomic evolution from preneoplasia to lung adenocarcinoma. Nat Commun. 2021 May 12; 12(1):2888. PMID: 33980839; PMCID: PMC8116337.
      Citations:    Fields:    
    23. Sinjab A, Han G, Treekitkarnmongkol W, Hara K, Brennan PM, Dang M, Hao D, Wang R, Dai E, Dejima H, Zhang J, Bogatenkova E, Sanchez-Espiridion B, Chang K, Little DR, Bazzi S, Tran LM, Krysan K, Behrens C, Duose DY, Parra ER, Raso MG, Solis LM, Fukuoka J, Zhang J, Sepesi B, Cascone T, Byers LA, Gibbons DL, Chen J, Moghaddam SJ, Ostrin EJ, Rosen D, Heymach JV, Scheet P, Dubinett SM, Fujimoto J, Wistuba II, Stevenson CS, Spira A, Wang L, Kadara H. Resolving the Spatial and Cellular Architecture of Lung Adenocarcinoma by Multiregion Single-Cell Sequencing. Cancer Discov. 2021 10; 11(10):2506-2523. PMID: 33972311; PMCID: PMC8487926.
      Citations: 12     Fields:    Translation:HumansCells
    24. Han G, Sinjab A, Hara K, Treekitkarnmongkol W, Brennan P, Chang K, Bogatenkova E, Sanchez-Espiridion B, Behrens C, Solis LM, Gao B, Girard L, Zhang J, Sepesi B, Cascone T, Byers LA, Gibbons DL, Chen J, Moghaddam SJ, Ostrin EJ, Scheet P, Fujimoto J, Shay J, Heymach JV, Minna JD, Dubinett S, Wistuba II, Stevenson CS, Spira AE, Wang L, Kadara H. Single-Cell Expression Landscape of SARS-CoV-2 Receptor ACE2 and Host Proteases in Normal and Malignant Lung Tissues from Pulmonary Adenocarcinoma Patients. Cancers (Basel). 2021 Mar 12; 13(6). PMID: 33809063; PMCID: PMC7998226.
      Citations: 3     
    25. Treekitkarnmongkol W, Hassane M, Sinjab A, Chang K, Hara K, Rahal Z, Zhang J, Lu W, Sivakumar S, McDowell TL, Kantrowitz J, Zhou J, Lang W, Xu L, Ochieng JK, Nunomura-Nakamura S, Deng S, Behrens C, Raso MG, Fukuoka J, Reuben A, Ostrin EJ, Parra E, Solis LM, Spira AE, McAllister F, Cascone T, Wistuba II, Moghaddam SJ, Scheet PA, Fujimoto J, Kadara H. Augmented Lipocalin-2 Is Associated with Chronic Obstructive Pulmonary Disease and Counteracts Lung Adenocarcinoma Development. Am J Respir Crit Care Med. 2021 01 01; 203(1):90-101. PMID: 32730093; PMCID: PMC7781147.
      Citations: 8     Fields:    Translation:HumansAnimals
    26. Deng S, Ramos-Castaneda M, Velasco WV, Clowers MJ, Gutierrez BA, Noble O, Dong Y, Zarghooni M, Alvarado L, Caetano MS, Yang S, Ostrin EJ, Behrens C, Wistuba II, Stabile LP, Kadara H, Watowich SS, Moghaddam SJ. Interplay between estrogen and Stat3/NF-?B-driven immunomodulation in lung cancer. Carcinogenesis. 2020 11 13; 41(11):1529-1542. PMID: 32603404; PMCID: PMC7896112.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    27. Ostrin EJ, Bantis LE, Wilson DO, Patel N, Wang R, Kundnani D, Adams-Haduch J, Dennison JB, Fahrmann JF, Chiu HT, Gazdar A, Feng Z, Yuan JM, Hanash SM. Contribution of a Blood-Based Protein Biomarker Panel to the Classification of Indeterminate Pulmonary Nodules. J Thorac Oncol. 2021 02; 16(2):228-236. PMID: 33137463; PMCID: PMC8218328.
      Citations: 3     Fields:    Translation:Humans
    28. Ostrin EJ, Sidransky D, Spira A, Hanash SM. Biomarkers for Lung Cancer Screening and Detection. Cancer Epidemiol Biomarkers Prev. 2020 12; 29(12):2411-2415. PMID: 33093160; PMCID: PMC7710615.
      Citations: 10     Fields:    Translation:Humans
    29. Fahrmann JF, Mao X, Irajizad E, Katayama H, Capello M, Tanaka I, Kato T, Wistuba II, Maitra A, Ostrin EJ, Hanash SM, Vykoukal J. Plasma-Derived Extracellular Vesicles Convey Protein Signatures that Reflect Pathophysiology in Lung and Pancreatic Adenocarcinomas. Cancers (Basel). 2020 May 02; 12(5). PMID: 32370304; PMCID: PMC7281335.
      Citations: 10     
    30. Fahrmann JF, Vykoukal JV, Ostrin EJ. Amino Acid Oncometabolism and Immunomodulation of the Tumor Microenvironment in Lung Cancer. Front Oncol. 2020; 10:276. PMID: 32266129; PMCID: PMC7105613.
      Citations: 7     
    31. Cain MP, Hutchison V, Flodby P, Crandall ED, Borok Z, Zhou B, Ostrin EJ, Wythe JD, Chen J, Vila Ellis L. Epithelial Vegfa Specifies a Distinct Endothelial Population in the Mouse Lung. Dev Cell. 2020 03 09; 52(5):617-630.e6. PMID: 32059772; PMCID: PMC7170573.
      Citations: 44     Fields:    Translation:AnimalsCells
    32. Little DR, Gerner-Mauro KN, Flodby P, Crandall ED, Borok Z, Akiyama H, Kimura S, Ostrin EJ, Chen J. Transcriptional control of lung alveolar type 1 cell development and maintenance by NK homeobox 2-1. Proc Natl Acad Sci U S A. 2019 10 08; 116(41):20545-20555. PMID: 31548395; PMCID: PMC6789920.
      Citations: 33     Fields:    Translation:AnimalsCells
    33. Hu X, Fujimoto J, Ying L, Fukuoka J, Ashizawa K, Sun W, Reuben A, Chow CW, McGranahan N, Chen R, Hu J, Godoy MC, Tabata K, Kuroda K, Shi L, Li J, Behrens C, Parra ER, Little LD, Gumbs C, Mao X, Song X, Tippen S, Thornton RL, Kadara H, Scheet P, Roarty E, Ostrin EJ, Wang X, Carter BW, Antonoff MB, Zhang J, Vaporciyan AA, Pass H, Swisher SG, Heymach JV, Lee JJ, Wistuba II, Hong WK, Futreal PA, Su D, Zhang J. Multi-region exome sequencing reveals genomic evolution from preneoplasia to lung adenocarcinoma. Nat Commun. 2019 07 05; 10(1):2978. PMID: 31278276; PMCID: PMC6611767.
      Citations: 34     Fields:    Translation:Humans
    34. Williams R, Bakshi S, Ostrin EJ, Ostrin LA. Continuous Objective Assessment of Near Work. Sci Rep. 2019 05 06; 9(1):6901. PMID: 31061427; PMCID: PMC6503122.
      Citations: 17     Fields:    Translation:Humans
    35. Park YH, Snook JD, Ostrin EJ, Kim S, Chen R, Frankfort BJ. Transcriptomic profiles of retinal ganglion cells are defined by the magnitude of intraocular pressure elevation in adult mice. Sci Rep. 2019 02 22; 9(1):2594. PMID: 30796289; PMCID: PMC6385489.
      Citations: 11     Fields:    Translation:AnimalsCells
    36. De la Garza MM, Cumpian AM, Daliri S, Castro-Pando S, Umer M, Gong L, Khosravi N, Caetano MS, Tran HT, Tuvim MJ, Ostrin EJ, Dickey BF, Evans CM, Moghaddam SJ, Ramos-Casta?eda M, Flores AG, Beltran EC. COPD-Type lung inflammation promotes K-ras mutant lung cancer through epithelial HIF-1a mediated tumor angiogenesis and proliferation. Oncotarget. 2018 Aug 31; 9(68):32972-32983. PMID: 30250643; PMCID: PMC6152479.
      Citations: 9     Fields:    
    37. Hanash SM, Ostrin EJ, Fahrmann JF. Blood based biomarkers beyond genomics for lung cancer screening. Transl Lung Cancer Res. 2018 Jun; 7(3):327-335. PMID: 30050770; PMCID: PMC6037962.
      Citations: 14     
    38. Khosravi N, Caetano MS, Cumpian AM, Unver N, Daliri S, Hernandez BJ, Gutierrez BA, Evans SE, Hanash S, Alekseev AM, Yang Y, Chang SH, Nurieva R, Kadara H, Chen J, Ostrin EJ, Moghaddam SJ, De la Garza Ramos C, Noble O. IL22 Promotes Kras-Mutant Lung Cancer by Induction of a Protumor Immune Response and Protection of Stemness Properties. Cancer Immunol Res. 2018 07; 6(7):788-797. PMID: 29764837; PMCID: PMC6030457.
      Citations: 33     Fields:    Translation:HumansAnimalsCells
    39. Ostrin EJ, Little DR, Gerner-Mauro KN, Sumner EA, Holt SE, Forcioli-Conti N, Akiyama H, Hanash SM, Kimura S, Huang SXL, Chen J, R?os-Corzo R, Ambrosio E. ?-Catenin maintains lung epithelial progenitors after lung specification. Development. 2018 03 09; 145(5). PMID: 29440304; PMCID: PMC5868997.
      Citations: 21     Fields:    Translation:AnimalsCells
    40. Unver N, Delgado O, Zeleke K, Cumpian A, Tang X, Caetano MS, Wang H, Katayama H, Yu H, Szabo E, Wistuba II, Moghaddam SJ, Hanash SM, Ostrin EJ. Reduced IL-6 levels and tumor-associated phospho-STAT3 are associated with reduced tumor development in a mouse model of lung cancer chemoprevention with myo-inositol. Int J Cancer. 2018 04 01; 142(7):1405-1417. PMID: 29134640; PMCID: PMC5805587.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    41. Vykoukal J, Sun N, Aguilar-Bonavides C, Katayama H, Tanaka I, Fahrmann JF, Capello M, Fujimoto J, Aguilar M, Wistuba II, Taguchi A, Ostrin EJ, Hanash SM. Plasma-derived extracellular vesicle proteins as a source of biomarkers for lung adenocarcinoma. Oncotarget. 2017 Nov 10; 8(56):95466-95480. PMID: 29221141; PMCID: PMC5707035.
      Citations: 35     Fields:    
    42. Tripathi SC, Fahrmann JF, Celiktas M, Aguilar M, Marini KD, Jolly MK, Katayama H, Wang H, Murage EN, Dennison JB, Watkins DN, Levine H, Ostrin EJ, Taguchi A, Hanash SM. MCAM Mediates Chemoresistance in Small-Cell Lung Cancer via the PI3K/AKT/SOX2 Signaling Pathway. Cancer Res. 2017 08 15; 77(16):4414-4425. PMID: 28646020; PMCID: PMC5880621.
      Citations: 43     Fields:    Translation:HumansAnimalsCells
    43. Tanaka I, Tripathi SC, Fahrmann JF, Aguilar-Bonavides C, Villalobos P, Delgado O, Dhillon D, Dennison JB, Ostrin EJ, Wang H, Behrens C, Do KA, Gazdar AF, Hanash SM, Taguchi A, ?eliktas M. Role of CPS1 in Cell Growth, Metabolism and Prognosis in LKB1-Inactivated Lung Adenocarcinoma. J Natl Cancer Inst. 2017 03 01; 109(3):1-9. PMID: 28376202; PMCID: PMC5198847.
      Citations: 39     Fields:    Translation:HumansCells
    44. Tsou P, Katayama H, Ostrin EJ, Hanash SM. The Emerging Role of B Cells in Tumor Immunity. Cancer Res. 2016 10 01; 76(19):5597-5601. PMID: 27634765.
      Citations: 131     Fields:    Translation:HumansCells
    45. Caetano MS, Zhang H, Cumpian AM, Gong L, Unver N, Ostrin EJ, Daliri S, Chang SH, Ochoa CE, Hanash S, Behrens C, Wistuba II, Sternberg C, Kadara H, Ferreira CG, Watowich SS, Moghaddam SJ. IL6 Blockade Reprograms the Lung Tumor Microenvironment to Limit the Development and Progression of K-ras-Mutant Lung Cancer. Cancer Res. 2016 06 01; 76(11):3189-99. PMID: 27197187; PMCID: PMC4891282.
      Citations: 83     Fields:    Translation:HumansAnimalsCells
    46. Tripathi SC, Peters HL, Taguchi A, Katayama H, Wang H, Momin A, Jolly MK, Celiktas M, Rodriguez-Canales J, Liu H, Behrens C, Wistuba II, Ben-Jacob E, Levine H, Molldrem JJ, Hanash SM, Ostrin EJ. Immunoproteasome deficiency is a feature of non-small cell lung cancer with a mesenchymal phenotype and is associated with a poor outcome. Proc Natl Acad Sci U S A. 2016 Mar 15; 113(11):E1555-64. PMID: 26929325; PMCID: PMC4801290.
      Citations: 77     Fields:    Translation:HumansCells
    47. Hanash S, Taguchi A, Wang H, Ostrin EJ. Deciphering the complexity of the cancer proteome for diagnostic applications. Expert Rev Mol Diagn. 2016; 16(4):399-405. PMID: 26694525.
      Citations: 3     Fields:    Translation:Humans
    48. Yang J, Hernandez BJ, Martinez Alanis D, Narvaez del Pilar O, Vila-Ellis L, Akiyama H, Evans SE, Ostrin EJ, Chen J. The development and plasticity of alveolar type 1 cells. Development. 2016 Jan 01; 143(1):54-65. PMID: 26586225; PMCID: PMC4725210.
      Citations: 56     Fields:    Translation:AnimalsCells
    49. Solberg OD, Ostrin EJ, Love MI, Peng JC, Bhakta NR, Hou L, Nguyen C, Solon M, Nguyen C, Barczak AJ, Zlock LT, Blagev DP, Finkbeiner WE, Ansel KM, Arron JR, Erle DJ, Woodruff PG. Airway epithelial miRNA expression is altered in asthma. Am J Respir Crit Care Med. 2012 Nov 15; 186(10):965-74. PMID: 22955319; PMCID: PMC3530212.
      Citations: 120     Fields:    Translation:HumansCellsCTClinical Trials
    50. Zeidner JF, Ostrin EJ, Sydnor E, Fine D, Sperati CJ. The tissue's the issue. Am J Med. 2010 May; 123(5):420-2. PMID: 20399317.
      Citations:    Fields:    Translation:Humans
    51. Ostrin EJ, Li Y, Hoffman K, Liu J, Wang K, Zhang L, Mardon G, Chen R. Genome-wide identification of direct targets of the Drosophila retinal determination protein Eyeless. Genome Res. 2006 Apr; 16(4):466-76. PMID: 16533912; PMCID: PMC1457028.
      Citations: 61     Fields:    Translation:Animals
    52. Pappu KS, Ostrin EJ, Middlebrooks BW, Sili BT, Chen R, Atkins MR, Gibbs R, Mardon G. Dual regulation and redundant function of two eye-specific enhancers of the Drosophila retinal determination gene dachshund. Development. 2005 Jun; 132(12):2895-905. PMID: 15930118.
      Citations: 48     Fields:    Translation:AnimalsCells
    53. Tavsanli BC, Ostrin EJ, Burgess HK, Middlebrooks BW, Pham TA, Mardon G. Structure-function analysis of the Drosophila retinal determination protein Dachshund. Dev Biol. 2004 Aug 01; 272(1):231-47. PMID: 15242803.
      Citations: 13     Fields:    Translation:AnimalsCells
    54. Rayapureddi JP, Kattamuri C, Steinmetz BD, Frankfort BJ, Ostrin EJ, Mardon G, Hegde RS. Eyes absent represents a class of protein tyrosine phosphatases. Nature. 2003 Nov 20; 426(6964):295-8. PMID: 14628052.
      Citations: 102     Fields:    Translation:AnimalsCells
    55. Lloyd TE, Verstreken P, Ostrin EJ, Phillippi A, Lichtarge O, Bellen HJ. A genome-wide search for synaptic vesicle cycle proteins in Drosophila. Neuron. 2000 Apr; 26(1):45-50. PMID: 10798391.
      Citations: 47     Fields:    Translation:AnimalsCells
    56. Geissler HJ, Davis KL, Laine GA, Ostrin EJ, Mehlhorn U, Hekmat K, Warters RD, Allen SJ. Myocardial protection with high-dose beta-blockade in acute myocardial ischemia. Eur J Cardiothorac Surg. 2000 Jan; 17(1):63-70. PMID: 10735414.
      Citations: 1     Fields:    Translation:Animals
    57. Deciphering the complexity of the cancer proteome for diagnostic applications. Expert Review of Molecular Diagnostics. 1-7.
    58. The emerging role of b cells in tumor immunity. Cancer Research. 76:5591-5601.
    59. IL6 blockade reprograms the lung tumor microenvironment to limit the development and progression of K-ras-mutant lung cancer. Cancer Research. 76:3189-3199.
    60. Immunoproteasome deficiency is a feature of non-small cell lung cancer with a mesenchymal phenotype and is associated with a poor outcome. Proceedings of the National Academy of Sciences of the United States of America. 113:E1555-E1564.
    61. The development and plasticity of alveolar type 1 cells. Development (Cambridge). 143:54-65.
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