NICHOLASNAVINNICHOLAS NAVIN9719NAVIN, NICHOLASAssociate Professorprns:coAuthorOfcoauthor ofFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressvivo:address1address line 1vivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provincevivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentDivisionvivo:hasResearchArearesearch areasvivo:hrJobTitleHR job titleInformation Resourcevivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:personInPositionpositionsPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPerson6767 Bertner StHouston77030-2603TXAuthorship 1714763Authorship 1779971Authorship 185611912807903Komuro A, Nagai M, Navin NE, Sudol MThe Journal of biological chemistryWW domain-containing protein YAP associates with ErbB-4 and acts as a co-transcriptional activator for the carboxyl-terminal fragment of ErbB-4 that translocates to the nucleus. J Biol Chem. 2003 Aug 29; 278(35):33334-41.J Biol Chem2003-06-13T00:00:002003WW domain-containing protein YAP associates with ErbB-4 and acts as a co-transcriptional activator for the carboxyl-terminal fragment of ErbB-4 that translocates to the nucleus.15273396Sebat J, Lakshmi B, Troge J, Alexander J, Young J, Lundin P, M?n?r S, Massa H, Walker M, Chi M, Navin N, Lucito R, Healy J, Hicks J, Ye K, Reiner A, Gilliam TC, Trask B, Patterson N, Zetterberg A, Wigler MScience (New York, N.Y.)Large-scale copy number polymorphism in the human genome. Science. 2004 Jul 23; 305(5683):525-8.Science2004-07-23T00:00:002004Large-scale copy number polymorphism in the human genome.16740623Navin N, Grubor V, Hicks J, Leibu E, Thomas E, Troge J, Riggs M, Lundin P, M?n?r S, Sebat J, Zetterberg A, Wigler MBioinformatics (Oxford, England)PROBER: oligonucleotide FISH probe design software. Bioinformatics. 2006 Oct 01; 22(19):2437-8.Bioinformatics2006-06-01T00:00:002006PROBER: oligonucleotide FISH probe design software.GeneticsInvestigational Cancer TherapeuticsLeukemiaSystems BiologyMD AndersonHENRY MARKKUERERHENRY MARK KUERER8727KUERER, HENRY MARKProfessorGORDON BMILLSGORDON B MILLS8620MILLS, GORDON BProfessor7.632460.00885576306research areas1.158130.039111990coauthor of78.554621.268260similar to1196selected publicationsFUNDAMERIC-BERNSTAMFUNDA MERIC-BERNSTAM8778MERIC-BERNSTAM, FUNDAProfessorMEDIGETTESHOMEMEDIGET TESHOME9897TESHOME, MEDIGETAssistant ProfessorAuthorship 2206164Authorship 2290981Authorship 230067115240876Thomas EE, Srebro N, Sebat J, Navin N, Healy J, Mishra B, Wigler MProceedings of the National Academy of Sciences of the United States of AmericaDistribution of short paired duplications in mammalian genomes. Proc Natl Acad Sci U S A. 2004 Jul 13; 101(28):10349-54.Proc Natl Acad Sci U S A2004-07-06T00:00:002004Distribution of short paired duplications in mammalian genomes.21399628Navin N, Kendall J, Troge J, Andrews P, Rodgers L, McIndoo J, Cook K, Stepansky A, Levy D, Esposito D, Muthuswamy L, Krasnitz A, McCombie WR, Hicks J, Wigler MNatureTumour evolution inferred by single-cell sequencing. Nature. 2011 Apr 07; 472(7341):90-4.Nature2011-03-13T00:00:002011Tumour evolution inferred by single-cell sequencing.21631906Navin N, Hicks JGenome medicineFuture medical applications of single-cell sequencing in cancer. Genome Med. 2011 May 31; 3(5):31.Genome Med2011-05-31T00:00:002011Future medical applications of single-cell sequencing in cancer.Authorship 2481744Authorship 2495076Authorship 25187610Authorship 2543921Authorship 2553391Authorship 25702012Authorship 257480217142309Hicks J, Krasnitz A, Lakshmi B, Navin NE, Riggs M, Leibu E, Esposito D, Alexander J, Troge J, Grubor V, Yoon S, Wigler M, Ye K, B?rresen-Dale AL, Naume B, Schlicting E, Norton L, H?gerstr?m T, Skoog L, Auer G, M?n?r S, Lundin P, Zetterberg AGenome researchNovel patterns of genome rearrangement and their association with survival in breast cancer. Genome Res. 2006 Dec; 16(12):1465-79.Genome Res2006-12-01T00:00:002006Novel patterns of genome rearrangement and their association with survival in breast cancer.17167050Pelham RJ, Rodgers L, Hall I, Lucito R, Nguyen KC, Navin N, Hicks J, Mu D, Powers S, Wigler M, Botstein DProceedings of the National Academy of Sciences of the United States of AmericaIdentification of alterations in DNA copy number in host stromal cells during tumor progression. Proc Natl Acad Sci U S A. 2006 Dec 26; 103(52):19848-53.Proc Natl Acad Sci U S A2006-12-13T00:00:002006Identification of alterations in DNA copy number in host stromal cells during tumor progression.18922857Grubor V, Krasnitz A, Troge JE, Meth JL, Lakshmi B, Kendall JT, Yamrom B, Alex G, Pai D, Navin N, Hufnagel LA, Lee YH, Cook K, Allen SL, Rai KR, Damle RN, Calissano C, Chiorazzi N, Wigler M, Esposito DBloodNovel genomic alterations and clonal evolution in chronic lymphocytic leukemia revealed by representational oligonucleotide microarray analysis (ROMA). Blood. 2009 Feb 05; 113(6):1294-303.Blood2008-10-15T00:00:002008Novel genomic alterations and clonal evolution in chronic lymphocytic leukemia revealed by representational oligonucleotide microarray analysis (ROMA).19903760Navin N, Krasnitz A, Rodgers L, Cook K, Meth J, Kendall J, Riggs M, Eberling Y, Troge J, Grubor V, Levy D, Lundin P, M?n?r S, Zetterberg A, Hicks J, Wigler MGenome researchInferring tumor progression from genomic heterogeneity. Genome Res. 2010 Jan; 20(1):68-80.Genome Res2009-11-10T00:00:002009Inferring tumor progression from genomic heterogeneity.20537601Navin NE, Hicks JMolecular oncologyTracing the tumor lineage. Mol Oncol. 2010 Jun; 4(3):267-83.Mol Oncol2010-05-05T00:00:002010Tracing the tumor lineage.21840483Chen M, Pratt CP, Zeeman ME, Schultz N, Taylor BS, O'Neill A, Castillo-Martin M, Nowak DG, Naguib A, Grace DM, Murn J, Navin N, Atwal GS, Sander C, Gerald WL, Cordon-Cardo C, Newton AC, Carver BS, Trotman LCCancer cellIdentification of PHLPP1 as a tumor suppressor reveals the role of feedback activation in PTEN-mutant prostate cancer progression. Cancer Cell. 2011 Aug 16; 20(2):173-86.Cancer Cell2011-08-16T00:00:002011Identification of PHLPP1 as a tumor suppressor reveals the role of feedback activation in PTEN-mutant prostate cancer progression.21965338Russnes HG, Navin N, Hicks J, Borresen-Dale ALThe Journal of clinical investigationInsight into the heterogeneity of breast cancer through next-generation sequencing. J Clin Invest. 2011 Oct; 121(10):3810-8.J Clin Invest2011-10-03T00:00:002011Insight into the heterogeneity of breast cancer through next-generation sequencing.Authorship 2700026Authorship 271936121799334Blake PM, Decker DA, Glennon TM, Liang YM, Losko S, Navin N, Suh KSCancer journal (Sudbury, Mass.)Toward an integrated knowledge environment to support modern oncology. Cancer J. 2011 Jul-Aug; 17(4):257-63.Cancer J2011-07-01T00:00:002011Toward an integrated knowledge environment to support modern oncology.24529750Navin NECell reportsTumor evolution in response to chemotherapy: phenotype versus genotype. Cell Rep. 2014 Feb 13; 6(3):417-9.Cell Rep2014-02-13T00:00:002014Tumor evolution in response to chemotherapy: phenotype versus genotype.Authorship 27447012Authorship 2751341622555242Baslan T, Kendall J, Rodgers L, Cox H, Riggs M, Stepansky A, Troge J, Ravi K, Esposito D, Lakshmi B, Wigler M, Navin N, Hicks JNature protocolsGenome-wide copy number analysis of single cells. Nat Protoc. 2012 May 03; 7(6):1024-41.Nat Protoc2012-05-03T00:00:002012Genome-wide copy number analysis of single cells.25079324Wang Y, Waters J, Leung ML, Unruh A, Roh W, Shi X, Chen K, Scheet P, Vattathil S, Liang H, Multani A, Zhang H, Zhao R, Michor F, Meric-Bernstam F, Navin NENatureClonal evolution in breast cancer revealed by single nucleus genome sequencing. Nature. 2014 Aug 14; 512(7513):155-60.Nature2014-07-30T00:00:002014Clonal evolution in breast cancer revealed by single nucleus genome sequencing.Authorship 2874882Authorship 2916891Authorship 2954337Authorship 2954784Authorship 2957521Authorship 29663015Authorship 2991701Authorship 3026127Authorship 303641223972288Chen K, Navin NE, Wang Y, Schmidt HK, Wallis JW, Niu B, Fan X, Zhao H, McLellan MD, Hoadley KA, Mardis ER, Ley TJ, Perou CM, Wilson RK, Ding LGenome biologyBreakTrans: uncovering the genomic architecture of gene fusions. Genome Biol. 2013 Aug 23; 14(8):R87.Genome Biol2013-08-23T00:00:002013BreakTrans: uncovering the genomic architecture of gene fusions.25222669Navin NEGenome biologyCancer genomics: one cell at a time. Genome Biol. 2014 Aug 30; 15(8):452.Genome Biol2014-08-30T00:00:002014Cancer genomics: one cell at a time.25729435Malhotra A, Wang Y, Waters J, Chen K, Meric-Bernstam F, Hall IM, Navin NEGenome medicinePloidy-Seq: inferring mutational chronology by sequencing polyploid tumor subpopulations. Genome Med. 2015; 7(1):6.Genome Med2015-01-28T00:00:002015Ploidy-Seq: inferring mutational chronology by sequencing polyploid tumor subpopulations.25853327Leung ML, Wang Y, Waters J, Navin NEGenome biologySNES: single nucleus exome sequencing. Genome Biol. 2015 Mar 25; 16:55.Genome Biol2015-03-25T00:00:002015SNES: single nucleus exome sequencing.26000845Wang Y, Navin NEMolecular cellAdvances and applications of single-cell sequencing technologies. Mol Cell. 2015 May 21; 58(4):598-609.Mol Cell2015-05-21T00:00:002015Advances and applications of single-cell sequencing technologies.26180099Navin NEScience translational medicineDelineating cancer evolution with single-cell sequencing. Sci Transl Med. 2015 Jul 15; 7(296):296fs29.Sci Transl Med2015-07-15T00:00:002015Delineating cancer evolution with single-cell sequencing.26248267Alizadeh AA, Aranda V, Bardelli A, Blanpain C, Bock C, Borowski C, Caldas C, Califano A, Doherty M, Elsner M, Esteller M, Fitzgerald R, Korbel JO, Lichter P, Mason CE, Navin N, Pe'er D, Polyak K, Roberts CW, Siu L, Snyder A, Stower H, Swanton C, Verhaak RG, Zenklusen JC, Zuber J, Zucman-Rossi JNature medicineToward understanding and exploiting tumor heterogeneity. Nat Med. 2015 Aug; 21(8):846-53.Nat Med2015-08-01T00:00:002015Toward understanding and exploiting tumor heterogeneity.26430160Navin NEGenome researchThe first five years of single-cell cancer genomics and beyond. Genome Res. 2015 Oct; 25(10):1499-507.Genome Res2015-10-01T00:00:002015The first five years of single-cell cancer genomics and beyond.26741407Leung ML, Wang Y, Kim C, Gao R, Jiang J, Sei E, Navin NENature protocolsHighly multiplexed targeted DNA sequencing from single nuclei. Nat Protoc. 2016 Feb; 11(2):214-235.Nat Protoc2016-01-07T00:00:002016Highly multiplexed targeted DNA sequencing from single nuclei.74Professor10Assistant Professor14Associate Professor42DirectorBreast Surgical OncologyKOICHITAKAHASHIKOICHI TAKAHASHI11823TAKAHASHI, KOICHIAssistant ProfessorSEBASTIANWINOCOURSEBASTIAN WINOCOUR12118WINOCOUR, SEBASTIANProfessor27479497Mann KM, Newberg JY, Black MA, Jones DJ, Amaya-Manzanares F, Guzman-Rojas L, Kodama T, Ward JM, Rust AG, van der Weyden L, Yew CC, Waters JL, Leung ML, Rogers K, Rogers SM, McNoe LA, Selvanesan L, Navin N, Jenkins NA, Copeland NG, Mann MBNature biotechnologyAnalyzing tumor heterogeneity and driver genes in single myeloid leukemia cells with SBCapSeq. Nat Biotechnol. 2016 09; 34(9):962-72.Nat Biotechnol2016-08-01T00:00:002016Analyzing tumor heterogeneity and driver genes in single myeloid leukemia cells with SBCapSeq.Authorship 841233Authorship 841395Authorship 841688Authorship 844915Authorship 845341Authorship 849291Authorship 851331Authorship 852374Authorship 854688Authorship 858114Authorship 860558Authorship 862926Authorship 866498Nature ProtocolsHighly multiplexed targeted DNA sequencing from single nuclei. Nature Protocols. 11:214-235.Highly multiplexed targeted DNA sequencing from single nucleiNature MethodsGenotyping tumor clones from single-cell data. Nature Methods. 13:555-556.Genotyping tumor clones from single-cell dataMolecular OncologyCorrigendum to "Tracing the tumor lineage" [Mol. Oncol. 4 (2010) 267-283]. Molecular Oncology. 5:302.Corrigendum to "Tracing the tumor lineage" [Mol. Oncol. 4 (2010) 267-283]Nature BiotechnologySingle-cell analysis at the threshold. Nature Biotechnology. 34:1111-1118.Single-cell analysis at the thresholdScience Translational MedicineDelineating cancer evolution with single-cell sequencing. Science Translational Medicine. 7.Delineating cancer evolution with single-cell sequencingGenome MedicinePloidy-Seq. Genome Medicine. 7.Ploidy-SeqGenome ResearchThe first five years of single-cell cancer genomics and beyond. Genome Research. 25:1499-1507.The first five years of single-cell cancer genomics and beyondJournal of PathologyGenome evolution in ductal carcinoma in situ. Journal of Pathology. 241:208-218.Genome evolution in ductal carcinoma in situNature BiotechnologyAnalyzing tumor heterogeneity and driver genes in single myeloid leukemia cells with SBCapSeq. Nature Biotechnology. 34:962-972.Analyzing tumor heterogeneity and driver genes in single myeloid leukemia cells with SBCapSeqNature GeneticsPunctuated copy number evolution and clonal stasis in triple-negative breast cancer. Nature Genetics. Punctuated copy number evolution and clonal stasis in triple-negative breast cancerGenome BiologyComputing tumor trees from single cells. Genome Biology. 17.Computing tumor trees from single cellsNature MethodsMonovar. Nature Methods. MonovarNature ProtocolsErratum. Nature Protocols. 11:616.Erratumtrue1ProfessorProfessorAuthorship 88975818D017422Procedures73224820.558848Sequence Analysis, DNAAuthorship 9050092Authorship 9055994Authorship 9056621Authorship 90743613Authorship 9081173Authorship 91069112Authorship 91375920Authorship 91589510Authorship 9178643Authorship 9225393Authorship 9261593Authorship 92699810Authorship 92730310Authorship 93339111Authorship 933720326914320Baslan T, Kendall J, Rodgers L, Cox H, Riggs M, Stepansky A, Troge J, Ravi K, Esposito D, Lakshmi B, Wigler M, Navin N, Hicks JNature protocolsCorrigendum: Genome-wide copy number analysis of single cells. Nat Protoc. 2016 Mar; 11(3):616.Nat Protoc2016-02-25T00:00:002016Corrigendum: Genome-wide copy number analysis of single cells.27088313Zafar H, Wang Y, Nakhleh L, Navin N, Chen KNature methodsMonovar: single-nucleotide variant detection in single cells. Nat Methods. 2016 06; 13(6):505-7.Nat Methods2016-04-18T00:00:002016Monovar: single-nucleotide variant detection in single cells.27230879Davis A, Navin NEGenome biologyComputing tumor trees from single cells. Genome Biol. 2016 05 26; 17(1):113.Genome Biol2016-05-26T00:00:002016Computing tumor trees from single cells.27526321Gao R, Davis A, McDonald TO, Sei E, Shi X, Wang Y, Tsai PC, Casasent A, Waters J, Zhang H, Meric-Bernstam F, Michor F, Navin NENature geneticsPunctuated copy number evolution and clonal stasis in triple-negative breast cancer. Nat Genet. 2016 10; 48(10):1119-30.Nat Genet2016-08-15T00:00:002016Punctuated copy number evolution and clonal stasis in triple-negative breast cancer.27355792Navin NE, Chen KNature methodsGenotyping tumor clones from single-cell data. Nat Methods. 2016 06 29; 13(7):555-6.Nat Methods2016-06-29T00:00:002016Genotyping tumor clones from single-cell data.27824834Chen X, Love JC, Navin NE, Pachter L, Stubbington MJ, Svensson V, Sweedler JV, Teichmann SANature biotechnologySingle-cell analysis at the threshold. Nat Biotechnol. 2016 11 08; 34(11):1111-1118.Nat Biotechnol2016-11-08T00:00:002016Single-cell analysis at the threshold.27861897Casasent AK, Edgerton M, Navin NEThe Journal of pathologyGenome evolution in ductal carcinoma in situ: invasion of the clones. J Pathol. 2017 Jan; 241(2):208-218.J Pathol2016-11-27T00:00:002016Genome evolution in ductal carcinoma in situ: invasion of the clones.28110020Davis A, Gao R, Navin NBiochimica et biophysica acta. Reviews on cancerTumor evolution: Linear, branching, neutral or punctuated? Biochim Biophys Acta Rev Cancer. 2017 Apr; 1867(2):151-161.Biochim Biophys Acta Rev Cancer2017-01-19T00:00:002017Tumor evolution: Linear, branching, neutral or punctuated?28546418Leung ML, Davis A, Gao R, Casasent A, Wang Y, Sei E, Vilar E, Maru D, Kopetz S, Navin NEGenome researchSingle-cell DNA sequencing reveals a late-dissemination model in metastatic colorectal cancer. Genome Res. 2017 08; 27(8):1287-1299.Genome Res2017-05-25T00:00:002017Single-cell DNA sequencing reveals a late-dissemination model in metastatic colorectal cancer.28645942Gausachs M, Borras E, Chang K, Gonzalez S, Azuara D, Delgado Amador A, Lopez-Doriga A, San Lucas FA, Sanjuan X, Paules MJ, Taggart MW, Davies GE, Ehli EA, Fowler J, Moreno V, Pineda M, You YN, Lynch PM, Lazaro C, Navin NE, Scheet PA, Hawk ET, Capella G, Vilar EClinical cancer research : an official journal of the American Association for Cancer ResearchMutational Heterogeneity in APC and KRAS Arises at the Crypt Level and Leads to Polyclonality in Early Colorectal Tumorigenesis. Clin Cancer Res. 2017 Oct 01; 23(19):5936-5947.Clin Cancer Res2017-06-23T00:00:002017Mutational Heterogeneity in APC and KRAS Arises at the Crypt Level and Leads to Polyclonality in Early Colorectal Tumorigenesis.28794488Gao R, Kim C, Sei E, Foukakis T, Crosetto N, Chan LK, Srinivasan M, Zhang H, Meric-Bernstam F, Navin NNature communicationsNanogrid single-nucleus RNA sequencing reveals phenotypic diversity in breast cancer. Nat Commun. 2017 08 09; 8(1):228.Nat Commun2017-08-09T00:00:002017Nanogrid single-nucleus RNA sequencing reveals phenotypic diversity in breast cancer.28927434Zafar H, Tzen A, Navin N, Chen K, Nakhleh LGenome biologySiFit: inferring tumor trees from single-cell sequencing data under finite-sites models. Genome Biol. 2017 09 19; 18(1):178.Genome Biol2017-09-19T00:00:002017SiFit: inferring tumor trees from single-cell sequencing data under finite-sites models.29307488Casasent AK, Schalck A, Gao R, Sei E, Long A, Pangburn W, Casasent T, Meric-Bernstam F, Edgerton ME, Navin NECellMulticlonal Invasion in Breast Tumors Identified by Topographic Single Cell Sequencing. Cell. 2018 01 11; 172(1-2):205-217.e12.Cell2018-01-04T00:00:002018Multiclonal Invasion in Breast Tumors Identified by Topographic Single Cell Sequencing.30077643Schalck A, Bernatchez C, Navin NTrends in molecular medicineResident Breast T Cells: The Troops Are Already There. Trends Mol Med. 2018 10; 24(10):821-822.Trends Mol Med2018-08-01T00:00:002018Resident Breast T Cells: The Troops Are Already There.30262850Zhang Y, Xiong S, Liu B, Pant V, Celii F, Chau G, Elizondo-Fraire AC, Yang P, You MJ, El-Naggar AK, Navin NE, Lozano GNature communicationsSomatic Trp53 mutations differentially drive breast cancer and evolution of metastases. Nat Commun. 2018 09 27; 9(1):3953.Nat Commun2018-09-27T00:00:002018Somatic Trp53 mutations differentially drive breast cancer and evolution of metastases.D018270Disorders28812150.592846Carcinoma, Ductal, BreastDepartment of Molecular & Human GeneticsDepartment of Pathology & ImmunologyDepartment of SurgerySurgery-Plastic Surgery DivMolecular & Human GeneticsPathologyBaylor College of MedicineJAMESLUPSKIJAMES LUPSKI29.71073630000000-95.396604500000003140LUPSKI, JAMESProfessorAuthorship 941425929681456Kim C, Gao R, Sei E, Brandt R, Hartman J, Hatschek T, Crosetto N, Foukakis T, Navin NECellChemoresistance Evolution in Triple-Negative Breast Cancer Delineated by Single-Cell Sequencing. Cell. 2018 05 03; 173(4):879-893.e13.Cell2018-04-19T00:00:002018Chemoresistance Evolution in Triple-Negative Breast Cancer Delineated by Single-Cell Sequencing.RICHARDGIBBSRICHARD GIBBS0.000000000000000.000000000000003131GIBBS, RICHARDDistinguished Service ProfessorD059010Procedures2964700.747709Single-Cell AnalysisD059014Procedures70222850.507539High-Throughput Nucleotide SequencingD060965Physiology1472520.83723Clonal EvolutionAuthorship 947088331096998Zafar H, Tzen A, Navin N, Chen K, Nakhleh LGenome biologyComments on the model parameters in "SiFit: inferring tumor trees from single-cell sequencing data under finite-sites models". Genome Biol. 2019 05 16; 20(1):95.Genome Biol2019-05-16T00:00:002019Comments on the model parameters in "SiFit: inferring tumor trees from single-cell sequencing data under finite-sites models".Authorship 9554301531515154Corn PG, Heath EI, Zurita A, Ramesh N, Xiao L, Sei E, Li-Ning-Tapia E, Tu SM, Subudhi SK, Wang J, Wang X, Efstathiou E, Thompson TC, Troncoso P, Navin N, Logothetis CJ, Aparicio AMThe Lancet. OncologyCabazitaxel plus carboplatin for the treatment of men with metastatic castration-resistant prostate cancers: a randomised, open-label, phase 1-2 trial. Lancet Oncol. 2019 10; 20(10):1432-1443.Lancet Oncol2019-09-09T00:00:002019Cabazitaxel plus carboplatin for the treatment of men with metastatic castration-resistant prostate cancers: a randomised, open-label, phase 1-2 trial.Authorship 957456231628257Zafar H, Navin N, Chen K, Nakhleh LGenome researchSiCloneFit: Bayesian inference of population structure, genotype, and phylogeny of tumor clones from single-cell genome sequencing data. Genome Res. 2019 11; 29(11):1847-1859.Genome Res2019-10-18T00:00:002019SiCloneFit: Bayesian inference of population structure, genotype, and phylogeny of tumor clones from single-cell genome sequencing data.Authorship 958000431658262Wang F, Liang S, Kumar T, Navin N, Chen KPLoS computational biologySCMarker: Ab initio marker selection for single cell transcriptome profiling. PLoS Comput Biol. 2019 10; 15(10):e1007445.PLoS Comput Biol2019-10-28T00:00:002019SCMarker: Ab initio marker selection for single cell transcriptome profiling.Authorship 960917331718533Davis A, Gao R, Navin NEBMC bioinformaticsSCOPIT: sample size calculations for single-cell sequencing experiments. BMC Bioinformatics. 2019 Nov 12; 20(1):566.BMC Bioinformatics2019-11-12T00:00:002019SCOPIT: sample size calculations for single-cell sequencing experiments.Authorship 9873493Authorship 9874422932289270Lim B, Lin Y, Navin NCancer cellAdvancing Cancer Research and Medicine with Single-Cell Genomics. Cancer Cell. 2020 04 13; 37(4):456-470.Cancer Cell2020-04-13T00:00:002020Advancing Cancer Research and Medicine with Single-Cell Genomics.32296058Mitra A, Andrews MC, Roh W, De Macedo MP, Hudgens CW, Carapeto F, Singh S, Reuben A, Wang F, Mao X, Song X, Wani K, Tippen S, Ng KS, Schalck A, Sakellariou-Thompson DA, Chen E, Reddy SM, Spencer CN, Wiesnoski D, Little LD, Gumbs C, Cooper ZA, Burton EM, Hwu P, Davies MA, Zhang J, Bernatchez C, Navin N, Sharma P, Allison JP, Wargo JA, Yee C, Tetzlaff MT, Hwu WJ, Lazar AJ, Futreal PANature communicationsSpatially resolved analyses link genomic and immune diversity and reveal unfavorable neutrophil activation in melanoma. Nat Commun. 2020 04 15; 11(1):1839.Nat Commun2020-04-15T00:00:002020Spatially resolved analyses link genomic and immune diversity and reveal unfavorable neutrophil activation in melanoma.Authorship 9881861232341031Malihi PD, Graf RP, Rodriguez A, Ramesh N, Lee J, Sutton R, Jiles R, Ruiz Velasco C, Sei E, Kolatkar A, Logothetis C, Navin NE, Corn P, Aparicio AM, Dittamore R, Hicks J, Kuhn P, Zurita AJClinical cancer research : an official journal of the American Association for Cancer ResearchSingle-Cell Circulating Tumor Cell Analysis Reveals Genomic Instability as a Distinctive Feature of Aggressive Prostate Cancer. Clin Cancer Res. 2020 08 01; 26(15):4143-4153.Clin Cancer Res2020-04-27T00:00:002020Single-Cell Circulating Tumor Cell Analysis Reveals Genomic Instability as a Distinctive Feature of Aggressive Prostate Cancer.Authorship 9909042432491160Manzo T, Prentice BM, Anderson KG, Raman A, Schalck A, Codreanu GS, Nava Lauson CB, Tiberti S, Raimondi A, Jones MA, Reyzer M, Bates BM, Spraggins JM, Patterson NH, McLean JA, Rai K, Tacchetti C, Tucci S, Wargo JA, Rodighiero S, Clise-Dwyer K, Sherrod SD, Kim M, Navin NE, Caprioli RM, Greenberg PD, Draetta G, Nezi LThe Journal of experimental medicineAccumulation of long-chain fatty acids in the tumor microenvironment drives dysfunction in intrapancreatic CD8+ T cells. J Exp Med. 2020 08 03; 217(8).J Exp Med2020-08-03T00:00:002020Accumulation of long-chain fatty acids in the tumor microenvironment drives dysfunction in intrapancreatic CD8+ T cells.Authorship 9937191032631448Ramesh N, Sei E, Tsai PC, Bai S, Zhao Y, Troncoso P, Corn PG, Logothetis C, Zurita AJ, Navin NEGenome biologyDecoding the evolutionary response to prostate cancer therapy by plasma genome sequencing. Genome Biol. 2020 07 06; 21(1):162.Genome Biol2020-07-06T00:00:002020Decoding the evolutionary response to prostate cancer therapy by plasma genome sequencing.Authorship 994297332658894Mallory XF, Edrisi M, Navin N, Nakhleh LPLoS computational biologyAssessing the performance of methods for copy number aberration detection from single-cell DNA sequencing data. PLoS Comput Biol. 2020 07; 16(7):e1008012.PLoS Comput Biol2020-07-13T00:00:002020Assessing the performance of methods for copy number aberration detection from single-cell DNA sequencing data.Authorship 997345332807205Mallory XF, Edrisi M, Navin N, Nakhleh LGenome biologyMethods for copy number aberration detection from single-cell DNA-sequencing data. Genome Biol. 2020 08 17; 21(1):208.Genome Biol2020-08-17T00:00:002020Methods for copy number aberration detection from single-cell DNA-sequencing data.Authorship 10032993033087716Morita K, Wang F, Jahn K, Hu T, Tanaka T, Sasaki Y, Kuipers J, Loghavi S, Wang SA, Yan Y, Furudate K, Matthews J, Little L, Gumbs C, Zhang J, Song X, Thompson E, Patel KP, Bueso-Ramos CE, DiNardo CD, Ravandi F, Jabbour E, Andreeff M, Cortes J, Bhalla K, Garcia-Manero G, Kantarjian H, Konopleva M, Nakada D, Navin N, Beerenwinkel N, Futreal PA, Takahashi KNature communicationsClonal evolution of acute myeloid leukemia revealed by high-throughput single-cell genomics. Nat Commun. 2020 10 21; 11(1):5327.Nat Commun2020-10-21T00:00:002020Clonal evolution of acute myeloid leukemia revealed by high-throughput single-cell genomics.Authorship 100518420Authorship 10053463033199705Naffar-Abu Amara S, Kuiken HJ, Selfors LM, Butler T, Leung ML, Leung CT, Kuhn EP, Kolarova T, Hage C, Ganesh K, Panayiotou R, Foster R, Rueda BR, Aktipis A, Spellman P, Ince TA, Xiu J, Oberley M, Gatalica Z, Navin N, Mills GB, Bronson RT, Brugge JSNature communicationsTransient commensal clonal interactions can drive tumor metastasis. Nat Commun. 2020 11 16; 11(1):5799.Nat Commun2020-11-16T00:00:002020Transient commensal clonal interactions can drive tumor metastasis.33214561Morita K, Wang F, Jahn K, Hu T, Tanaka T, Sasaki Y, Kuipers J, Loghavi S, Wang SA, Yan Y, Furudate K, Matthews J, Little L, Gumbs C, Zhang J, Song X, Thompson E, Patel KP, Bueso-Ramos CE, DiNardo CD, Ravandi F, Jabbour E, Andreeff M, Cortes J, Bhalla K, Garcia-Manero G, Kantarjian H, Konopleva M, Nakada D, Navin N, Beerenwinkel N, Futreal PA, Takahashi KNature communicationsPublisher Correction: Clonal evolution of acute myeloid leukemia revealed by high-throughput single-cell genomics. Nat Commun. 2020 Nov 19; 11(1):5996.Nat Commun2020-11-19T00:00:002020Publisher Correction: Clonal evolution of acute myeloid leukemia revealed by high-throughput single-cell genomics.Authorship 10094841733462507Gao R, Bai S, Henderson YC, Lin Y, Schalck A, Yan Y, Kumar T, Hu M, Sei E, Davis A, Wang F, Shaitelman SF, Wang JR, Chen K, Moulder S, Lai SY, Navin NENature biotechnologyDelineating copy number and clonal substructure in human tumors from single-cell transcriptomes. Nat Biotechnol. 2021 05; 39(5):599-608.Nat Biotechnol2021-01-18T00:00:002021Delineating copy number and clonal substructure in human tumors from single-cell transcriptomes.Authorship 10122221033622385Wang F, Wang Q, Mohanty V, Liang S, Dou J, Han J, Minussi DC, Gao R, Ding L, Navin N, Chen KGenome biologyMEDALT: single-cell copy number lineage tracing enabling gene discovery. Genome Biol. 2021 02 23; 22(1):70.Genome Biol2021-02-23T00:00:002021MEDALT: single-cell copy number lineage tracing enabling gene discovery.Authorship 10145002733762732Minussi DC, Nicholson MD, Ye H, Davis A, Wang K, Baker T, Tarabichi M, Sei E, Du H, Rabbani M, Peng C, Hu M, Bai S, Lin YW, Schalck A, Multani A, Ma J, McDonald TO, Casasent A, Barrera A, Chen H, Lim B, Arun B, Meric-Bernstam F, Van Loo P, Michor F, Navin NENatureBreast tumours maintain a reservoir of subclonal diversity during expansion. Nature. 2021 04; 592(7853):302-308.Nature2021-03-24T00:00:002021Breast tumours maintain a reservoir of subclonal diversity during expansion.Authorship 10182313033972555Morita K, Wang F, Jahn K, Hu T, Tanaka T, Sasaki Y, Kuipers J, Loghavi S, Wang SA, Yan Y, Furudate K, Matthews J, Little L, Gumbs C, Zhang J, Song X, Thompson E, Patel KP, Bueso-Ramos CE, DiNardo CD, Ravandi F, Jabbour E, Andreeff M, Cortes J, Bhalla K, Garcia-Manero G, Kantarjian H, Konopleva M, Nakada D, Navin N, Beerenwinkel N, Futreal PA, Takahashi KNature communicationsAuthor Correction: Clonal evolution of acute myeloid leukemia revealed by high-throughput single-cell genomics. Nat Commun. 2021 May 10; 12(1):2823.Nat Commun2021-05-10T00:00:002021Author Correction: Clonal evolution of acute myeloid leukemia revealed by high-throughput single-cell genomics.true1Distinguished Service ProfessorDistinguished Service ProfessorAuthorship 10308581434594038Johnson KC, Anderson KJ, Courtois ET, Gujar AD, Barthel FP, Varn FS, Luo D, Seignon M, Yi E, Kim H, Estecio MRH, Zhao D, Tang M, Navin NE, Maurya R, Ngan CY, Verburg N, de Witt Hamer PC, Bulsara K, Samuels ML, Das S, Robson P, Verhaak RGWNature geneticsSingle-cell multimodal glioma analyses identify epigenetic regulators of cellular plasticity and environmental stress response. Nat Genet. 2021 10; 53(10):1456-1468.Nat Genet2021-09-30T00:00:002021Single-cell multimodal glioma analyses identify epigenetic regulators of cellular plasticity and environmental stress response.Authorship 10319691234686316Wang K, Xiao Z, Yan Y, Ye R, Hu M, Bai S, Sei E, Qiao Y, Chen H, Lim B, Lin SH, Navin NEMolecular cellSimple oligonucleotide-based multiplexing of single-cell chromatin accessibility. Mol Cell. 2021 10 21; 81(20):4319-4332.e10.Mol Cell2021-10-21T00:00:002021Simple oligonucleotide-based multiplexing of single-cell chromatin accessibility.Authorship 1038677935314812Wei R, He S, Bai S, Sei E, Hu M, Thompson A, Chen K, Krishnamurthy S, Navin NENature biotechnologySpatial charting of single-cell transcriptomes in tissues. Nat Biotechnol. 2022 08; 40(8):1190-1199.Nat Biotechnol2022-03-21T00:00:002022Spatial charting of single-cell transcriptomes in tissues.Authorship 10434472235385726Han H, Wang Y, Curto J, Gurrapu S, Laudato S, Rumandla A, Chakraborty G, Wang X, Chen H, Jiang Y, Kumar D, Caggiano EG, Capogiri M, Zhang B, Ji Y, Maity SN, Hu M, Bai S, Aparicio AM, Efstathiou E, Logothetis CJ, Navin N, Navone NM, Chen Y, Giancotti FGCell reportsMesenchymal and stem-like prostate cancer linked to therapy-induced lineage plasticity and metastasis. Cell Rep. 2022 04 05; 39(1):110595.Cell Rep2022-04-05T00:00:002022Mesenchymal and stem-like prostate cancer linked to therapy-induced lineage plasticity and metastasis.Authorship 10473554635681052Lips EH, Kumar T, Megalios A, Visser LL, Sheinman M, Fortunato A, Shah V, Hoogstraat M, Sei E, Mallo D, Roman-Escorza M, Ahmed AA, Xu M, van den Belt-Dusebout AW, Brugman W, Casasent AK, Clements K, Davies HR, Fu L, Grigoriadis A, Hardman TM, King LM, Krete M, Kristel P, de Maaker M, Maley CC, Marks JR, Menegaz BA, Mulder L, Nieboer F, Nowinski S, Pinder S, Quist J, Salinas-Souza C, Schaapveld M, Schmidt MK, Shaaban AM, Shami R, Sridharan M, Zhang J, Stobart H, Collyar D, Nik-Zainal S, Wessels LFA, Hwang ES, Navin NE, Futreal PA, Grand Challenge PRECISION consortium, Thompson AM, Wesseling J, Sawyer EJNature geneticsGenomic analysis defines clonal relationships of ductal carcinoma in situ and recurrent invasive breast cancer. Nat Genet. 2022 06; 54(6):850-860.Nat Genet2022-06-09T00:00:002022Genomic analysis defines clonal relationships of ductal carcinoma in situ and recurrent invasive breast cancer.Authorship 10486721735718094Mathew MT, Antoniou A, Ramesh N, Hu M, Gaither J, Mouhlas D, Hashimoto S, Humphrey M, Matthews T, Hunter JM, Reshmi S, Schultz M, Lee K, Pfau R, Cottrell C, McBride KL, Navin NE, Chaudhari BP, Leung MLThe Journal of molecular diagnostics : JMDA Decade's Experience in Pediatric Chromosomal Microarray Reveals Distinct Characteristics Across Ordering Specialties. J Mol Diagn. 2022 09; 24(9):1031-1040.J Mol Diagn2022-06-16T00:00:002022A Decade's Experience in Pediatric Chromosomal Microarray Reveals Distinct Characteristics Across Ordering Specialties.Authorship 10507911835849783Schalck A, Sakellariou-Thompson D, Forget MA, Sei E, Hughes TG, Reuben A, Bai S, Hu M, Kumar T, Hurd MW, Katz MHG, Tzeng CD, Pant S, Javle M, Fogelman DR, Maitra A, Haymaker CL, Kim MP, Navin NE, Bernatchez CCancer discoverySingle-Cell Sequencing Reveals Trajectory of Tumor-Infiltrating Lymphocyte States in Pancreatic Cancer. Cancer Discov. 2022 10 05; 12(10):2330-2349.Cancer Discov2022-10-05T00:00:002022Single-Cell Sequencing Reveals Trajectory of Tumor-Infiltrating Lymphocyte States in Pancreatic Cancer.Authorship 10571068Authorship 105452325Authorship 105828112Authorship 105565112Authorship 105568717Authorship 10618591636261705Casasent AK, Almekinders MM, Mulder C, Bhattacharjee P, Collyar D, Thompson AM, Jonkers J, Lips EH, van Rheenen J, Hwang ES, Nik-Zainal S, Navin NE, Wesseling J, Grand Challenge PRECISION ConsortiumNature reviews. CancerLearning to distinguish progressive and non-progressive ductal carcinoma in situ. Nat Rev Cancer. 2022 12; 22(12):663-678.Nat Rev Cancer2022-10-19T00:00:002022Learning to distinguish progressive and non-progressive ductal carcinoma in situ.36522469Casasent AK, Almekinders MM, Mulder C, Bhattacharjee P, Collyar D, Thompson AM, Jonkers J, Lips EH, van Rheenen J, Hwang ES, Nik-Zainal S, Navin NE, Wesseling J, Grand Challenge PRECISION ConsortiumNature reviews. CancerAuthor Correction: Learning to distinguish progressive and non-progressive ductal carcinoma in situ. Nat Rev Cancer. 2023 Feb; 23(2):112.Nat Rev Cancer2023-02-01T00:00:002023Author Correction: Learning to distinguish progressive and non-progressive ductal carcinoma in situ.36585453Gulhati P, Schalck A, Jiang S, Shang X, Wu CJ, Hou P, Ruiz SH, Soto LS, Parra E, Ying H, Han J, Dey P, Li J, Deng P, Sei E, Maeda DY, Zebala JA, Spring DJ, Kim M, Wang H, Maitra A, Moore D, Clise-Dwyer K, Wang YA, Navin NE, DePinho RANature cancerTargeting T cell checkpoints 41BB and LAG3 and myeloid cell CXCR1/CXCR2 results in antitumor immunity and durable response in pancreatic cancer. Nat Cancer. 2023 01; 4(1):62-80.Nat Cancer2022-12-30T00:00:002022Targeting T cell checkpoints 41BB and LAG3 and myeloid cell CXCR1/CXCR2 results in antitumor immunity and durable response in pancreatic cancer.36419822Wu HJ, Temko D, Maliga Z, Moreira AL, Sei E, Minussi DC, Dean J, Lee C, Xu Q, Hochart G, Jacobson CA, Yapp C, Schapiro D, Sorger PK, Seeley EH, Navin N, Downey RJ, Michor FCell genomicsSpatial intra-tumor heterogeneity is associated with survival of lung adenocarcinoma patients. Cell Genom. 2022 Aug 10; 2(8).Cell Genom2022-08-10T00:00:002022Spatial intra-tumor heterogeneity is associated with survival of lung adenocarcinoma patients.36525493Wang X, Semba T, Manyam GC, Wang J, Shao S, Bertucci F, Finetti P, Krishnamurthy S, Phi LTH, Pearson T, Van Laere SJ, Burks JK, Cohen EN, Reuben JM, Yang F, Min H, Navin N, Trinh VN, Iwase T, Batra H, Shen Y, Zhang X, Tripathy D, Ueno NTScience advancesEGFR is a master switch between immunosuppressive and immunoactive tumor microenvironment in inflammatory breast cancer. Sci Adv. 2022 12 16; 8(50):eabn7983.Sci Adv2022-12-16T00:00:002022EGFR is a master switch between immunosuppressive and immunoactive tumor microenvironment in inflammatory breast cancer.36376909Kaufmann TL, Petkovic M, Watkins TBK, Colliver EC, Laskina S, Thapa N, Minussi DC, Navin N, Swanton C, Van Loo P, Haase K, Tarabichi M, Schwarz RFGenome biologyMEDICC2: whole-genome doubling aware copy-number phylogenies for cancer evolution. Genome Biol. 2022 11 14; 23(1):241.Genome Biol2022-11-14T00:00:002022MEDICC2: whole-genome doubling aware copy-number phylogenies for cancer evolution.Authorship 1063917536777188Leighton J, Hu M, Sei E, Meric-Bernstam F, Navin NECell genomicsReconstructing mutational lineages in breast cancer by multi-patient-targeted single-cell DNA sequencing. Cell Genom. 2023 Jan 11; 3(1):100215.Cell Genom2022-11-09T00:00:002022Reconstructing mutational lineages in breast cancer by multi-patient-targeted single-cell DNA sequencing.Authorship 106841714Authorship 10679372137067911Gencel-Augusto J, Su X, Qi Y, Whitley EM, Pant V, Xiong S, Shah V, Lin J, Perez E, Fiorotto ML, Mahmud I, Jain AK, Lorenzi PL, Navin NE, Richie ER, Lozano GCancer discoveryDimeric p53 Mutant Elicits Unique Tumor-Suppressive Activities through an Altered Metabolic Program. Cancer Discov. 2023 05 04; 13(5):1230-1249.Cancer Discov2023-05-04T00:00:002023Dimeric p53 Mutant Elicits Unique Tumor-Suppressive Activities through an Altered Metabolic Program.37053016Lu L, Wang JR, Henderson YC, Bai S, Yang J, Hu M, Shiau CK, Pan T, Yan Y, Tran TM, Li J, Kieser R, Zhao X, Wang J, Nurieva R, Williams MD, Cabanillas ME, Dadu R, Busaidy NL, Zafereo M, Navin N, Lai SY, Gao RThe Journal of clinical investigationAnaplastic transformation in thyroid cancer revealed by single-cell transcriptomics. J Clin Invest. 2023 06 01; 133(11).J Clin Invest2023-06-01T00:00:002023Anaplastic transformation in thyroid cancer revealed by single-cell transcriptomics.true1ProfessorProfessorAuthorship 10702353737163043Kumar T, Nee K, Wei R, He S, Nguyen QH, Bai S, Blake K, Gong Y, Pein M, Sei E, Hu M, Casasent A, Thennavan A, Li J, Tran T, Chen K, Nilges B, Kashikar N, Braubach O, Cheikh BB, Nikulina N, Chen H, Teshome M, Menegaz B, Javaid H, Nagi C, Montalvan J, Tifrea DF, Edwards R, Lin E, Parajuli R, Winocour S, Thompson A, Lim B, Lawson DA, Kessenbrock K, Navin NbioRxiv : the preprint server for biologyA spatially resolved single cell genomic atlas of the adult human breast. bioRxiv. 2023 Apr 25.bioRxiv2023-04-25T00:00:002023A spatially resolved single cell genomic atlas of the adult human breast.Authorship 107399012Authorship 10731054037254069Truong DD, Lamhamedi-Cherradi SE, Porter RW, Krishnan S, Swaminathan J, Gibson A, Lazar AJ, Livingston JA, Gopalakrishnan V, Gordon N, Daw NC, Navin NE, Gorlick R, Ludwig JABMC cancerDissociation protocols used for sarcoma tissues bias the transcriptome observed in single-cell and single-nucleus RNA sequencing. BMC Cancer. 2023 May 31; 23(1):488.BMC Cancer2023-05-31T00:00:002023Dissociation protocols used for sarcoma tissues bias the transcriptome observed in single-cell and single-nucleus RNA sequencing.37380767Kumar T, Nee K, Wei R, He S, Nguyen QH, Bai S, Blake K, Pein M, Gong Y, Sei E, Hu M, Casasent AK, Thennavan A, Li J, Tran T, Chen K, Nilges B, Kashikar N, Braubach O, Ben Cheikh B, Nikulina N, Chen H, Teshome M, Menegaz B, Javaid H, Nagi C, Montalvan J, Lev T, Mallya S, Tifrea DF, Edwards R, Lin E, Parajuli R, Hanson S, Winocour S, Thompson A, Lim B, Lawson DA, Kessenbrock K, Navin NNatureA spatially resolved single-cell genomic atlas of the adult human breast. Nature. 2023 Aug; 620(7972):181-191.Nature2023-06-28T00:00:002023A spatially resolved single-cell genomic atlas of the adult human breast.Authorship 107762716Authorship 10773113337592035Dou J, Tan Y, Kock KH, Wang J, Cheng X, Tan LM, Han KY, Hon CC, Park WY, Shin JW, Jin H, Wang Y, Chen H, Ding L, Prabhakar S, Navin N, Chen R, Chen KNature biotechnologySingle-nucleotide variant calling in single-cell sequencing data with Monopogen. Nat Biotechnol. 2023 Aug 17.Nat Biotechnol2023-08-17T00:00:002023Single-nucleotide variant calling in single-cell sequencing data with Monopogen.37586362Wang K, Kumar T, Wang J, Minussi DC, Sei E, Li J, Tran TM, Thennavan A, Hu M, Casasent AK, Xiao Z, Bai S, Yang L, King LM, Shah V, Kristel P, van der Borden CL, Marks JR, Zhao Y, Zurita AJ, Aparicio A, Chapin B, Ye J, Zhang J, Gibbons DL, Grand Challenge PRECISION Consortium, Sawyer E, Thompson AM, Futreal A, Hwang ES, Wesseling J, Lips EH, Navin NECellArchival single-cell genomics reveals persistent subclones during DCIS progression. Cell. 2023 08 31; 186(18):3968-3982.e15.Cell2023-08-15T00:00:002023Archival single-cell genomics reveals persistent subclones during DCIS progression.true1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1Assistant ProfessorAssistant Professortrue1Associate ProfessorAssociate Professortrue1Assistant ProfessorAssistant Professortrue1ProfessorProfessorCHANDANDEEPNAGICHANDANDEEP NAGI7639NAGI, CHANDANDEEPProfessor