MARY ELIZABETHEDGERTONMARY ELIZABETH EDGERTON9369EDGERTON, MARY ELIZABETHAssociate Professorprns:coAuthorOfcoauthor ofFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressvivo:address1address line 1vivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provincevivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentDivisionvivo:hasResearchArearesearch areasvivo:hrJobTitleHR job titleInformation Resourcevivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:personInPositionpositionsPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPerson1515 Holcombe BlvdHouston77030-4009TXAuthorship 1679991Authorship 1705483Authorship 1853732Authorship 1865074Authorship 1886116Authorship 1888042Authorship 1892644Authorship 192679710086240Edgerton ME, Hoda RS, Gupta PKDiagnostic cytopathologyCytologic diagnosis of metastatic ovarian adenocarcinoma in the urinary bladder: a case report and review of the literature. Diagn Cytopathol. 1999 Mar; 20(3):156-9.Diagn Cytopathol1999-03-01T00:00:001999Cytologic diagnosis of metastatic ovarian adenocarcinoma in the urinary bladder: a case report and review of the literature.11333279Simpson JF, Page DL, Edgerton MEJournal of the National Cancer Institutep53 in Mammary ductal carcinoma in situ, mutations in high-grade lesions only? J Natl Cancer Inst. 2001 May 02; 93(9):666-7.J Natl Cancer Inst2001-05-02T00:00:002001p53 in Mammary ductal carcinoma in situ, mutations in high-grade lesions only?20121597Albarracin C, Edgerton ME, Gilcrease MZ, Huo L, Krishnamurthy S, Middleton LP, Resetkova E, Sahin AA, Sneige N, Fraser WS, Wu YArchives of pathology & laboratory medicineIs it too soon to start reporting HER2 genetic heterogeneity? Arch Pathol Lab Med. 2010 Feb; 134(2):162-3; author reply 163.Arch Pathol Lab Med2010-02-01T00:00:002010Is it too soon to start reporting HER2 genetic heterogeneity?20940121Broom BM, Sulman EP, Do KA, Edgerton ME, Kenneth D. AldapeInternational journal of bioinformatics research and applicationsBagged gene shaving for the robust clustering of high-throughput data. Int J Bioinform Res Appl. 2010; 6(4):326-43.Int J Bioinform Res Appl2010-01-01T00:00:002010Bagged gene shaving for the robust clustering of high-throughput data.22342935Macklin P, Edgerton ME, Thompson AM, Cristini VJournal of theoretical biologyPatient-calibrated agent-based modelling of ductal carcinoma in situ (DCIS): from microscopic measurements to macroscopic predictions of clinical progression. J Theor Biol. 2012 May 21; 301:122-40.J Theor Biol2012-02-09T00:00:002012Patient-calibrated agent-based modelling of ductal carcinoma in situ (DCIS): from microscopic measurements to macroscopic predictions of clinical progression.Bioinformatics & Computational BiologyGeneticsInvestigational Cancer TherapeuticsPalliative Care & Rehabilitation MedicineSystems BiologyMD AndersonHENRY MARKKUERERHENRY MARK KUERER8727KUERER, HENRY MARKProfessorKELLY KHUNTKELLY K HUNT8555HUNT, KELLY KProfessorGORDON BMILLSGORDON B MILLS8620MILLS, GORDON BProfessorEDUARDOBRUERAEDUARDO BRUERA8804BRUERA, EDUARDOProfessor0.5560180.00256313195research areas0.3128570.020640853coauthor of14.75543.3846160similar to1148selected publicationsPHYU PAUNGPHYU P AUNG9707AUNG, PHYU PAssistant ProfessorNICHOLASNAVINNICHOLAS NAVIN9719NAVIN, NICHOLASAssociate ProfessorFUNDAMERIC-BERNSTAMFUNDA MERIC-BERNSTAM8778MERIC-BERNSTAM, FUNDAProfessorCONSTANCEALBARRACINCONSTANCE ALBARRACIN8954ALBARRACIN, CONSTANCEProfessorBRADLEY MCINTOSHBROOMBRADLEY MCINTOSH BROOM9214BROOM, BRADLEY MCINTOSHProfessorAuthorship 2165002Authorship 2213164Authorship 2224372Authorship 2242782Authorship 2255715Authorship 22610912Authorship 2267511Authorship 2277901Authorship 23065738895069Morel DW, Edgerton ME, Warner GE, Johnson WJ, Phillips MC, Rothblat GHJournal of lipid researchComparison of the intracellular metabolism and trafficking of 25-hydroxycholesterol and cholesterol in macrophages. J Lipid Res. 1996 Sep; 37(9):2041-51.J Lipid Res1996-09-01T00:00:001996Comparison of the intracellular metabolism and trafficking of 25-hydroxycholesterol and cholesterol in macrophages.14581339Yamagata N, Shyr Y, Yanagisawa K, Edgerton M, Dang TP, Gonzalez A, Nadaf S, Larsen P, Roberts JR, Nesbitt JC, Jensen R, Levy S, Moore JH, Minna JD, Carbone DPClinical cancer research : an official journal of the American Association for Cancer ResearchA training-testing approach to the molecular classification of resected non-small cell lung cancer. Clin Cancer Res. 2003 Oct 15; 9(13):4695-704.Clin Cancer Res2003-10-15T00:00:002003A training-testing approach to the molecular classification of resected non-small cell lung cancer.16779041Frey L, Edgerton ME, Fisher DH, Tang L, Chen ZAMIA ... Annual Symposium proceedings. AMIA SymposiumUsing prior knowledge and rule induction methods to discover molecular markers of prognosis in lung cancer. AMIA Annu Symp Proc. 2005; 256-60.AMIA Annu Symp Proc2005-01-01T00:00:002005Using prior knowledge and rule induction methods to discover molecular markers of prognosis in lung cancer.17911916Frey L, Edgerton M, Fisher D, Levy SStudies in health technology and informaticsEnsemble stump classifiers and gene expression signatures in lung cancer. Stud Health Technol Inform. 2007; 129(Pt 2):1255-9.Stud Health Technol Inform2007-01-01T00:00:002007Ensemble stump classifiers and gene expression signatures in lung cancer.18300793Khalifeh IM, Albarracin C, Diaz LK, Symmans FW, Edgerton ME, Hwang RF, Sneige NThe American journal of surgical pathologyClinical, histopathologic, and immunohistochemical features of microglandular adenosis and transition into in situ and invasive carcinoma. Am J Surg Pathol. 2008 Apr; 32(4):544-52.Am J Surg Pathol2008-04-01T00:00:002008Clinical, histopathologic, and immunohistochemical features of microglandular adenosis and transition into in situ and invasive carcinoma.19064970Kuerer HM, Albarracin CT, Yang WT, Cardiff RD, Brewster AM, Symmans WF, Hylton NM, Middleton LP, Krishnamurthy S, Perkins GH, Babiera G, Edgerton ME, Czerniecki BJ, Arun BK, Hortobagyi GNJournal of clinical oncology : official journal of the American Society of Clinical OncologyDuctal carcinoma in situ: state of the science and roadmap to advance the field. J Clin Oncol. 2009 Jan 10; 27(2):279-88.J Clin Oncol2008-12-08T00:00:002008Ductal carcinoma in situ: state of the science and roadmap to advance the field.19259407Edgerton ME, Morrison C, LiVolsi VA, Moskaluk CA, Qualman SJ, Washington MK, Grizzle WECancer informaticsA standards based ontological approach to information handling for use by organizations providing human tissue for research. Cancer Inform. 2008; 6:127-37.Cancer Inform2008-04-10T00:00:002008A standards based ontological approach to information handling for use by organizations providing human tissue for research.20525187Edgerton ME, Grizzle WE, Washington MKBMC medical informatics and decision makingThe deployment of a tissue request tracking system for the CHTN: a case study in managing change in informatics for biobanking operations. BMC Med Inform Decis Mak. 2010 Jun 02; 10:32.BMC Med Inform Decis Mak2010-06-02T00:00:002010The deployment of a tissue request tracking system for the CHTN: a case study in managing change in informatics for biobanking operations.21714919Frey LJ, Piccolo SR, Edgerton MEBMC medical genomicsMultiplicity: an organizing principle for cancers and somatic mutations. BMC Med Genomics. 2011 Jun 29; 4:52.BMC Med Genomics2011-06-29T00:00:002011Multiplicity: an organizing principle for cancers and somatic mutations.Authorship 2384491Authorship 2384601Authorship 2436161Authorship 2452494Authorship 2519841Authorship 2520133Authorship 2574921Authorship 25874937213336Edgerton ME, Moore TA, Greenwood CThe Biochemical journalInvestigations into the effect of acid on the spectral and kinetic properties of purple membrane from Halobacterium halobium. Biochem J. 1980 Sep 01; 189(3):413-20.Biochem J1980-09-01T00:00:001980Investigations into the effect of acid on the spectral and kinetic properties of purple membrane from Halobacterium halobium.7306878Edgerton ME, Brimblecombe PCanadian journal of microbiologyThermodynamics of halobacterial environments. Can J Microbiol. 1981 Sep; 27(9):899-909.Can J Microbiol1981-09-01T00:00:001981Thermodynamics of halobacterial environments.12050079Edgerton ME, Taylor R, Powell JI, Hunter L, Simon R, Liu ETBioinformatics (Oxford, England)A bioinformatics tool to select sequences for microarray studies of mouse models of oncogenesis. Bioinformatics. 2002 May; 18(5):774-5.Bioinformatics2002-05-01T00:00:002002A bioinformatics tool to select sequences for microarray studies of mouse models of oncogenesis.14580254Xie L, Law BK, Aakre ME, Edgerton M, Shyr Y, Bhowmick NA, Moses HLBreast cancer research : BCRTransforming growth factor beta-regulated gene expression in a mouse mammary gland epithelial cell line. Breast Cancer Res. 2003; 5(6):R187-98.Breast Cancer Res2003-08-20T00:00:002003Transforming growth factor beta-regulated gene expression in a mouse mammary gland epithelial cell line.18999005Riben M, Wade G, Edgerton M, Kilbourne JAMIA ... Annual Symposium proceedings. AMIA SymposiumAligning tissue banking data models for caBIG interoperability. AMIA Annu Symp Proc. 2008 Nov 06; 1109.AMIA Annu Symp Proc2008-11-06T00:00:002008Aligning tissue banking data models for caBIG interoperability.19455237Edgerton ME, Fisher DH, Tang L, Frey LJ, Chen ZCancer informaticsData mining for gene networks relevant to poor prognosis in lung cancer via backward-chaining rule induction. Cancer Inform. 2007 Feb 10; 3:93-114.Cancer Inform2007-02-10T00:00:002007Data mining for gene networks relevant to poor prognosis in lung cancer via backward-chaining rule induction.21988888Edgerton ME, Chuang YL, Macklin P, Yang W, Bearer EL, Cristini VAnalytical cellular pathology (Amsterdam)A novel, patient-specific mathematical pathology approach for assessment of surgical volume: application to ductal carcinoma in situ of the breast. Anal Cell Pathol (Amst). 2011; 34(5):247-63.Anal Cell Pathol (Amst)2011-01-01T00:00:002011A novel, patient-specific mathematical pathology approach for assessment of surgical volume: application to ductal carcinoma in situ of the breast.23171633Rog CJ, Chekuri SC, Edgerton MEBMC research notesChallenges of the information age: the impact of false discovery on pathway identification. BMC Res Notes. 2012 Nov 21; 5:647.BMC Res Notes2012-11-21T00:00:002012Challenges of the information age: the impact of false discovery on pathway identification.Authorship 2627992Authorship 2628001Authorship 2628011Authorship 2662706Authorship 2684422Authorship 269422426337Moore TA, Edgerton ME, Parr G, Greenwood C, Perham RNThe Biochemical journalStudies of an acid-induced species of purple membrane from Halobacterium halobium. Biochem J. 1978 May 01; 171(2):469-76.Biochem J1978-05-01T00:00:001978Studies of an acid-induced species of purple membrane from Halobacterium halobium.31300Edgerton ME, Moore TA, Greenwood CFEBS lettersSalt reversal of the acid-induced changes in purple membrane from Halobacterium halobium. FEBS Lett. 1978 Nov 01; 95(1):35-9.FEBS Lett1978-11-01T00:00:001978Salt reversal of the acid-induced changes in purple membrane from Halobacterium halobium.41777Edgerton ME, Greenwood CBiochemical Society transactionsEvidence for a model of regeneration of a protonated species, bR, from a phototransient, M, in the photochemical cycle of bacteriorhodopsin from Halobacterium halobium [proceedings]. Biochem Soc Trans. 1979 Oct; 7(5):1075-7.Biochem Soc Trans1979-10-01T00:00:001979Evidence for a model of regeneration of a protonated species, bR, from a phototransient, M, in the photochemical cycle of bacteriorhodopsin from Halobacterium halobium [proceedings].14612504Massion PP, Taflan PM, Jamshedur Rahman SM, Yildiz P, Shyr Y, Edgerton ME, Westfall MD, Roberts JR, Pietenpol JA, Carbone DP, Gonzalez ALCancer researchSignificance of p63 amplification and overexpression in lung cancer development and prognosis. Cancer Res. 2003 Nov 01; 63(21):7113-21.Cancer Res2003-11-01T00:00:002003Significance of p63 amplification and overexpression in lung cancer development and prognosis.19366802Frieboes HB, Edgerton ME, Fruehauf JP, Rose FR, Worrall LK, Gatenby RA, Ferrari M, Cristini VCancer researchPrediction of drug response in breast cancer using integrative experimental/computational modeling. Cancer Res. 2009 May 15; 69(10):4484-92.Cancer Res2009-04-14T00:00:002009Prediction of drug response in breast cancer using integrative experimental/computational modeling.19747394Sanga S, Broom BM, Cristini V, Edgerton MEBMC medical genomicsGene expression meta-analysis supports existence of molecular apocrine breast cancer with a role for androgen receptor and implies interactions with ErbB family. BMC Med Genomics. 2009 Sep 11; 2:59.BMC Med Genomics2009-09-11T00:00:002009Gene expression meta-analysis supports existence of molecular apocrine breast cancer with a role for androgen receptor and implies interactions with ErbB family.Authorship 277145212769826Berman JJ, Edgerton ME, Friedman BABMC medical informatics and decision makingThe tissue microarray data exchange specification: a community-based, open source tool for sharing tissue microarray data. BMC Med Inform Decis Mak. 2003 May 23; 3:5.BMC Med Inform Decis Mak2003-05-23T00:00:002003The tissue microarray data exchange specification: a community-based, open source tool for sharing tissue microarray data.Authorship 279291674Professor10Assistant Professor14Associate ProfessorBreast Surgical Oncology21858162Thompson PA, Brewster AM, Kim-Anh D, Baladandayuthapani V, Broom BM, Edgerton ME, Hahn KM, Murray JL, Sahin A, Tsavachidis S, Wang Y, Zhang L, Hortobagyi GN, Mills GB, Bondy MLPloS oneSelective genomic copy number imbalances and probability of recurrence in early-stage breast cancer. PLoS One. 2011; 6(8):e23543.PLoS One2011-08-12T00:00:002011Selective genomic copy number imbalances and probability of recurrence in early-stage breast cancer.22014043Perry KD, Reynolds C, Rosen DG, Edgerton ME, T Albarracin C, Gilcrease MZ, Sahin AA, Abraham SC, Wu YHistopathologyMetastatic neuroendocrine tumour in the breast: a potential mimic of in-situ and invasive mammary carcinoma. Histopathology. 2011 Oct; 59(4):619-30.Histopathology2011-10-01T00:00:002011Metastatic neuroendocrine tumour in the breast: a potential mimic of in-situ and invasive mammary carcinoma.Authorship 845536Authorship 849595Authorship 850718Authorship 854209Authorship 854589Authorship 859805Authorship 861269Authorship 861470Authorship 862752Journal of PathologyGenome evolution in ductal carcinoma in situ. Journal of Pathology. 241:208-218.Genome evolution in ductal carcinoma in situDiscrete cell modeling. 88-122.Discrete cell modelingSearching for meaningful feature interactions with backward-chaining rule induction. 86-96.Searching for meaningful feature interactions with backward-chaining rule inductionAgent-based cell modeling. 206-234.Agent-based cell modelingBMC Medical Informatics and Decision MakingThe tissue microarray data exchange specification. BMC Medical Informatics and Decision Making. 3:1-9.The tissue microarray data exchange specificationIntelligent Data AnalysisBackward chaining rule induction. Intelligent Data Analysis. 10:397-417.Backward chaining rule inductionNeural network with K-means clustering via PCA for gene expression profile analysis. 670-673.Neural network with K-means clustering via PCA for gene expression profile analysisEnsemble stump classifiers and gene expression signatures in lung cancer. 1255-1259.Ensemble stump classifiers and gene expression signatures in lung cancerClinical Cancer Research2013 HIPAA Changes Provide Opportunities and Challenges for Researchers. Clinical Cancer Research. 22:533-539.2013 HIPAA Changes Provide Opportunities and Challenges for ResearchersD020408Concepts & Ideas15230.978055Health Insurance Portability and Accountability ActD030541Concepts & Ideas3197440.758421Databases, GeneticD012108Living Beings1071470.870966Research PersonnelD002285Disorders1926720.683453Carcinoma, Intraductal, NoninfiltratingAuthorship 9042584Authorship 9158949Authorship 9178632Authorship 922489726832744Freedman RS, Cantor SB, Merriman KW, Edgerton MEClinical cancer research : an official journal of the American Association for Cancer Research2013 HIPAA Changes Provide Opportunities and Challenges for Researchers: Perspectives from a Cancer Center. Clin Cancer Res. 2016 Feb 01; 22(3):533-9.Clin Cancer Res2016-02-01T00:00:0020162013 HIPAA Changes Provide Opportunities and Challenges for Researchers: Perspectives from a Cancer Center.27861897Casasent AK, Edgerton M, Navin NEThe Journal of pathologyGenome evolution in ductal carcinoma in situ: invasion of the clones. J Pathol. 2017 Jan; 241(2):208-218.J Pathol2016-11-27T00:00:002016Genome evolution in ductal carcinoma in situ: invasion of the clones.28928852Kuerer HM, Smith BD, Chavez-MacGregor M, Albarracin C, Barcenas CH, Santiago L, Edgerton ME, Rauch GM, Giordano SH, Sahin A, Krishnamurthy S, Woodward W, Tripathy D, Yang WT, Hunt KKJournal of CancerDCIS Margins and Breast Conservation: MD Anderson Cancer Center Multidisciplinary Practice Guidelines and Outcomes. J Cancer. 2017; 8(14):2653-2662.J Cancer2017-08-22T00:00:002017DCIS Margins and Breast Conservation: MD Anderson Cancer Center Multidisciplinary Practice Guidelines and Outcomes.29307488Casasent AK, Schalck A, Gao R, Sei E, Long A, Pangburn W, Casasent T, Meric-Bernstam F, Edgerton ME, Navin NECellMulticlonal Invasion in Breast Tumors Identified by Topographic Single Cell Sequencing. Cell. 2018 01 11; 172(1-2):205-217.e12.Cell2018-01-04T00:00:002018Multiclonal Invasion in Breast Tumors Identified by Topographic Single Cell Sequencing.D000046ObjectsOrganizations4416630.752995Academic Medical CentersPathology24071849Cancer Genome Atlas Research Network, Weinstein JN, Collisson EA, Mills GB, Shaw KR, Ozenberger BA, Ellrott K, Shmulevich I, Sander C, Stuart JMNature geneticsThe Cancer Genome Atlas Pan-Cancer analysis project. Nat Genet. 2013 Oct; 45(10):1113-20.Nat Genet2013-10-01T00:00:002013The Cancer Genome Atlas Pan-Cancer analysis project.Authorship 954787831473252Wang S, Oh DY, Leventaki V, Drakos E, Zhang R, Sahin AA, Resetkova E, Edgerton ME, Wu W, Claret FXCancer lettersMicroRNA-17 acts as a tumor chemosensitizer by targeting JAB1/CSN5 in triple-negative breast cancer. Cancer Lett. 2019 11 28; 465:12-23.Cancer Lett2019-08-29T00:00:002019MicroRNA-17 acts as a tumor chemosensitizer by targeting JAB1/CSN5 in triple-negative breast cancer.Authorship 10800681237756559Shehabeldin A, Rohra P, Sellen LD, Zhao J, Alqaidy D, Aramin H, Hameed N, Perez YE, Lai Z, Tong YT, Milton DR, Edgerton ME, Fuller G, Hansel D, Prieto VG, Ballester LY, Aung PPArchives of pathology & laboratory medicineUtility of Whole Slide Imaging for Intraoperative Consultation: Experience of a Large Academic Center. Arch Pathol Lab Med. 2023 Sep 26.Arch Pathol Lab Med2023-09-26T00:00:002023Utility of Whole Slide Imaging for Intraoperative Consultation: Experience of a Large Academic Center.true1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1Associate ProfessorAssociate Professortrue1Assistant ProfessorAssistant Professortrue1Associate ProfessorAssociate Professortrue1ProfessorProfessor24999802Han L, Yuan Y, Zheng S, Yang Y, Li J, Edgerton ME, Diao L, Xu Y, Verhaak RGW, Liang HNature communicationsThe Pan-Cancer analysis of pseudogene expression reveals biologically and clinically relevant tumour subtypes. Nat Commun. 2014 Jul 07; 5:3963.Nat Commun2014-07-07T00:00:002014The Pan-Cancer analysis of pseudogene expression reveals biologically and clinically relevant tumour subtypes.